MCID: PRT019
MIFTS: 39

Protein-Losing Enteropathy malady

Category: Gastrointestinal diseases

Aliases & Classifications for Protein-Losing Enteropathy

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Aliases & Descriptions for Protein-Losing Enteropathy:

Name: Protein-Losing Enteropathy 10 12
Protein-Losing Enteropathies 47 36 65
 
Enteropathy, Exudative 10
Exudative Enteropathy 10

Characteristics:



Classifications:



External Ids:

Disease Ontology10 DOID:10611
SNOMED-CT59 22542007, 66972006
MeSH36 D011504
UMLS65 C0033680

Summaries for Protein-Losing Enteropathy

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Wikipedia:68 Protein losing enteropathy refers to any condition of the gastrointestinal tract (e.g. damage to the gut... more...

MalaCards based summary: Protein-Losing Enteropathy, also known as protein-losing enteropathies, is related to neurofibroma and cholestasis, and has symptoms including hypoproteinemia, budd-chiari syndrome and abnormality of the intestine. An important gene associated with Protein-Losing Enteropathy is MPI (Mannose Phosphate Isomerase), and among its related pathways are N-Glycan biosynthesis and Synthesis of substrates in N-glycan biosythesis. Affiliated tissues include lung, breast and bone.

Related Diseases for Protein-Losing Enteropathy

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Graphical network of the top 20 diseases related to Protein-Losing Enteropathy:



Diseases related to protein-losing enteropathy

Symptoms for Protein-Losing Enteropathy

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HPO human phenotypes related to Protein-Losing Enteropathy:

(show all 10)
id Description Frequency HPO Source Accession
1 hypoproteinemia HP:0003075
2 budd-chiari syndrome HP:0002639
3 abnormality of the intestine HP:0002242
4 abdominal pain HP:0002027
5 diarrhea HP:0002014
6 iron deficiency anemia HP:0001891
7 ascites HP:0001541
8 growth delay HP:0001510
9 clubbing HP:0001217
10 edema HP:0000969

Drugs & Therapeutics for Protein-Losing Enteropathy

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Drugs for Protein-Losing Enteropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Heparinapproved, investigationalPhase 17199005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
2calcium heparinPhase 1719
3
substance Pinvestigational21733507-63-036511, 44359816
Synonyms:
 
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
4Vasodilator Agents2926
5Vasoactive intestinal peptide640077-57-4
6Neuroprotective Agents1376
7Gastrointestinal Agents6401
8neurokinin A220
9Protective Agents5651

Interventional clinical trials:

idNameStatusNCT IDPhase
1Pilot/Ph I Safety and Efficacy of ODSH in Protein Losing Enteropathy Secondary to Single Ventricle Palliative SurgeryTerminatedNCT01161641Phase 1
2Plastic Bronchitis and Protein Losing Enteropathy in Children With Single Ventricle PhysiologyCompletedNCT01563757
3National Lymphatic Disease and Lymphedema RegistryRecruitingNCT01336790

Search NIH Clinical Center for Protein-Losing Enteropathy


Cochrane evidence based reviews: protein-losing enteropathies

Genetic Tests for Protein-Losing Enteropathy

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Anatomical Context for Protein-Losing Enteropathy

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MalaCards organs/tissues related to Protein-Losing Enteropathy:

33
Lung, Breast, Bone, Thyroid, Prostate, T cells, Endothelial

Animal Models for Protein-Losing Enteropathy or affiliated genes

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Publications for Protein-Losing Enteropathy

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Articles related to Protein-Losing Enteropathy:

(show top 50)    (show all 538)
idTitleAuthorsYear
1
Global Perceptions of Food Allergy Thresholds in 16 Countries. (27176492)
2016
2
Spontaneous regression of laryngeal squamous cell carcinoma. (26443436)
2015
3
Clinical Efficacy Observation of Acupuncture Treatment for Nonarteritic Anterior Ischemic Optic Neuropathy. (26089945)
2015
4
Fecal stream diversion and mucosal cytokine levels in collagenous colitis: A case report. (26019474)
2015
5
Veterinary Medicine and Multi-Omics Research for Future Nutrition Targets: Metabolomics and Transcriptomics of the Common Degenerative Mitral Valve Disease in Dogs. (26154239)
2015
6
Management of congenital fourth cranial nerve palsy. (24661367)
2014
7
A rare cause of acute pancreatitis: Percutaneous mechanical rheolytic thrombectomy of deep venous thrombosis. (25403575)
2014
8
Methemoglobinemia and hemolytic anemia after rasburicase administration in a child with leukemia. (21057874)
2013
9
Prognostic significance of autophagy-related protein expression in resected pancreatic ductal adenocarcinoma. (23429496)
2013
10
Basic research: Salt wasting in distal renal tubular acidosis-new look, old problem. (24189652)
2013
11
The blame game: cervical cancer, knowledge of its link to human papillomavirus and stigma. (24006882)
2013
12
Duration of treatment for candidemia and risk for late-onset ocular candidiasis. (23212461)
2013
13
Less-Invasive Pedicled Omental-Cranial Transposition in Pediatric Patients with Moyamoya Disease and Failed Prior Revascularization. (23921707)
2013
14
Icariin enhances the healing of rapid palatal expansion induced root resorption in rats. (22818561)
2012
15
SNX3-dependent regulation of epidermal growth factor receptor (EGFR) trafficking and degradation by aspirin in epidermoid carcinoma (A-431) cells. (22159558)
2012
16
Assessment of liver fibrosis and cirrhosis by aspartate aminotransferase-to-platelet ratio index in children with biliary atresia. (20531020)
2010
17
Portal vein thrombosis and budd-Chiari syndrome. (19150317)
2009
18
Safety and efficacy of purified human C1-esterase inhibitor in the treatment of patients with sepsis]. (19499717)
2009
19
Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism. (19295164)
2009
20
Leptin as a neuroprotective agent. (18222172)
2008
21
A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice. (18316591)
2008
22
Primary hyperparathyroidism is associated with marked impairment of GH response to acylated ghrelin. (18221398)
2008
23
DISC1-kendrin interaction is involved in centrosomal microtubule network formation. (18955030)
2008
24
Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. (18030365)
2007
25
Sexual fetishism in a quail (Coturnix japonica) model system: test of reproductive success. (17115864)
2006
26
Acrylamide and glycidamide: genotoxic effects in V79-cells and human blood. (15668108)
2005
27
Altered structure and expression of RB1 gene and increased phosphorylation of pRb in human vestibular schwannomas. (15881662)
2005
28
The role of pentraxin 3 in the inflammatory and immune response]. (16047839)
2005
29
Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis. (14729469)
2004
30
Sildenafil citrate alleviates pulmonary hypertension after hypoxia and reoxygenation with cardiopulmonary bypass. (15454147)
2004
31
The role of the LRPPRC (leucine-rich pentatricopeptide repeat cassette) gene in cytochrome oxidase assembly: mutation causes lowered levels of COX (cytochrome c oxidase) I and COX III mRNA. (15139850)
2004
32
Monitoring manufacturing process yields, purity and stability of structural variants of PEGylated staphylokinase mutant SY161 by quantitative reverse-phase chromatography. (12884399)
2003
33
Disease-associated bias in T helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma or melanoma. (12208877)
2002
34
Unilateral absence of the external oblique muscle with hypoplasia of the rectus abdominis muscle in a patient with Poland syndrome. (12447072)
2002
35
Treatment of hairy cell leukemia with cladribine (2-chlorodeoxyadenosine) by subcutaneous bolus injection: a phase II study. (12377655)
2002
36
Multiple lesions of granuloma annulare following BCG vaccination: case report and review of the literature. (11737453)
2001
37
Site-specific risk of cutaneous malignant melanoma and pattern of sun exposure in New Zealand. (10699940)
2000
38
The role of vitamin D3 receptor mRNA in the proliferation of hepatocellular carcinoma. (10791215)
2000
39
Expression of a subset of steroid receptor cofactors is associated with progesterone receptor expression in meningiomas. (10999746)
2000
40
Prolonged extreme thrombocytosis associated with neurofibromatosis type 1. (9042140)
1997
41
Purification and characterization of a eukaryotic type 1 topoisomerase from pea chloroplast. (8106424)
1994
42
Renal and electrolyte complications of congestive heart failure and effects of therapy with angiotensin-converting enzyme inhibitors. (1558426)
1992
43
Coexpression of type I and type II human macrophage scavenger receptors in macrophages of various organs and foam cells in atherosclerotic lesions. (1519666)
1992
44
Human recombinant interleukin-1 alpha protection against the lethality of endotoxin and experimental sepsis in mice. (2038179)
1991
45
Diastematomyelia in 172 children: the impact of modern neuroradiology. (2135195)
1990-1991
46
Biochemical and molecular genetic characterization of a new variant prealbumin associated with hereditary amyloidosis. (3722385)
1986
47
The effect of triiodothyronine on cervical lymphoid structures, thyroid activity, IgG and IgM immunoglobulin level and exophthalmos in Graves' disease. (4184992)
1969
48
DYSGERMINOMA OF THE OVARY: A CLINICAL REPORT OF 20 CASES. (14248209)
1964
49
Kernicterus. (14819084)
1951
50
DIFFERENTIATION BETWEEN YAWS AND SYPHILIS. (18741593)
1930

Variations for Protein-Losing Enteropathy

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Expression for genes affiliated with Protein-Losing Enteropathy

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Search GEO for disease gene expression data for Protein-Losing Enteropathy.

Pathways for genes affiliated with Protein-Losing Enteropathy

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GO Terms for genes affiliated with Protein-Losing Enteropathy

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Cellular components related to Protein-Losing Enteropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endosome membraneGO:00100089.3ANTXR2, TF

Biological processes related to Protein-Losing Enteropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1dolichol-linked oligosaccharide biosynthetic processGO:00064889.3ALG6, ALG8, MPI
2protein N-linked glycosylation via asparagineGO:00182798.9ALG8, MPI, SERPINA1
3post-translational protein modificationGO:00436878.4ALG6, ALG8, MPI, SERPINA1

Molecular functions related to Protein-Losing Enteropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activityGO:00422819.2ALG6, ALG8

Sources for Protein-Losing Enteropathy

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet