MCID: PSD007
MIFTS: 68

Pseudomyxoma Peritonei malady

Rare diseases, Cancer diseases categories

Summaries for Pseudomyxoma Peritonei

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NIH Rare Diseases:43 Pseudomyxoma peritonei is a tumor that most often begins in the appendix.  as the tumor grows, tumor cells may spread into the peritoneal cavity and land on other nearby organs (such as the ovaries or intestines), sometimes forming additional tumors on the surface of these organs.  pseudomyxoma peritonei is extremely unlikely to grow into these organs (to become invasive) or spread to more distant parts of the body (metastasize); therefore, it is not usually thought of as a malignant tumor.  it is rare, occurring in approximately two out of a million people, and women are affected two to three times more frequently than men.  the first symptoms of pseudomyxoma peritonei are an increase in the size of the belly, appendicitis, or the finding of a mass on the ovary during medical imaging tests.   last updated: 9/27/2011

MalaCards based summary: Pseudomyxoma Peritonei, also known as syndrome of pseudomyxoma peritonei, is related to cystadenocarcinoma and mucinous cystadenocarcinoma, and has symptoms including ascites, abnormality of the peritoneum and abnormality of the abdominal wall. An important gene associated with Pseudomyxoma Peritonei is MUC2 (mucin 2, oligomeric mucus/gel-forming), and among its related pathways are Incretin Synthesis, Secretion, and Inactivation and Selected targets of Oct 3 4. The compounds exisulind and sodium bisulfite have been mentioned in the context of this disorder. Affiliated tissues include appendix, colon and ovary, and related mouse phenotypes are pigmentation and tumorigenesis.

Disease Ontology:10 An appendix cancer that is characterized by progressive accumulation of mucus-secreting tumor cells within the abdomen and pelvis.

Wikipedia:65 Pseudomyxoma peritonei is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that... more...

Aliases & Classifications for Pseudomyxoma Peritonei

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Sources:
10Disease Ontology, 43NIH Rare Diseases, 12DISEASES, 45Novoseek, 49Orphanet, 62UMLS, 57SNOMED-CT, 35MeSH, 40NCIt, 28ICD10 via Orphanet, 63UMLS via Orphanet, 36MESH via Orphanet
See all sources

Pseudomyxoma Peritonei, Aliases & Descriptions:

Name: Pseudomyxoma Peritonei 10 43 12 45 49 62
Syndrome of Pseudomyxoma Peritonei 43 62
Gelatinous Ascites 43 49
Adenomucinosis 43 49
 
Pmp 43 49
Ascites, Gelatinous 62
Mucinous Ascites 10


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Orphanet: 49 
Rare tumors


Characteristics (Orphanet epidemiological data):

49
pseudomyxoma peritonei:
Prevalence: 1-9/1000000 (Worldwide); Age of onset: Adult; Age of death: any age


External Ids:

Disease Ontology10 DOID:3559
MeSH35 D011553
NCIt40 C3345
Orphanet49 26790
ICD10 via Orphanet28 C78.6
UMLS via Orphanet63 C0033822
MESH via Orphanet36 D011553

Related Diseases for Pseudomyxoma Peritonei

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Diseases related to Pseudomyxoma Peritonei via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 150)
idRelated DiseaseScoreTop Affiliating Genes
1cystadenocarcinoma31.3CEACAM5, MUC5AC, MUC2
2mucinous cystadenocarcinoma31.2KRT20, KRT7, CEACAM7
3adenocarcinoma31.0CTNNB1, CDH2, CDH1, CDX2, KRT20, KRT7
4cystadenoma31.0KRT7, KRAS
5mesothelioma30.7CDH2, KRT20, KRT7, PSG2, CEACAM7, CEACAM5
6villous adenoma30.4MUC5AC, APC
7colorectal cancer30.4CTNNB1, APC
8breast cancer30.3CDH1, TP53
9adenoma30.3CTNNB1, CDH2, CDH1, CDX2, KRT20, KRT7
10melanoma29.9CTNNB1, CDH2, CDH1, CDX2, KRAS, PSG2
11peritonitis11.0
12mucinous adenocarcinoma10.9
13teratoma10.7
14cystic teratoma10.7
15mucinous adenocarcinoma of the appendix10.6
16endometriosis10.5
17peritoneal mesothelioma10.5
18appendiceal neoplasm10.5
19hepatitis10.4
20ovarian mucinous cystadenocarcinoma10.4
21intestinal obstruction10.4
22gelatinous ascites10.4
23urachal cyst10.4
24sacrococcygeal teratoma10.2
25acute pancreatitis10.2
26pyometritis10.2
27melioidosis10.2
28neurofibromatosis10.2
29acromegaly10.2
30colloid carcinoma of the pancreas10.2
31appendicitis10.2
32infertility10.2
33abdominal tuberculosis10.2
34cervicitis10.2
35dermatomyositis10.2
36hyperglycemia10.2
37mature teratoma10.2
38ovarian cyst10.2
39ovarian cystadenocarcinoma10.2
40pancreatitis10.2
41retinitis10.2
42tuberculosis10.2
43cerebellar degeneration10.2
44paraneoplastic cerebellar degeneration10.2
45paraneoplastic syndromes10.2
46malignant peritoneal mesothelioma10.2
47ampulla of vater carcinoma10.1MUC2
48endometrial adenocarcinoma10.1
49bladder adenocarcinoma10.1CDX2
50metanephric adenoma10.1KRT7

Graphical network of the top 20 diseases related to Pseudomyxoma Peritonei:



Diseases related to pseudomyxoma peritonei

Symptoms for Pseudomyxoma Peritonei

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Symptoms:

 49 (show all 19)
  • anomalies of the abdominal wall
  • ascitis
  • peritoneal diseases
  • inflammatory intestinal disease
  • herniae
  • nausea/vomiting/regurgitation/merycism/hyperemesis
  • acute abdominal pain/colic
  • constipation
  • intestinal obstruction/ileus
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • lymphadenopathy/polyadenopathies
  • pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria
  • digestive neoplasm/tumor/carcinoma/cancer
  • estomach/gastric neoplasm/tumor/carcinoma/cancer
  • colon neoplasm/tumor/carcinoma/cancer
  • pancreatic/pancreas neoplasm/tumor/carcinoma/cancer
  • ovary/fallopian tube neoplasm/tumor/carcinoma/cancer (excl. teratoma/germinoma)
  • early death/lethality
  • weight loss/loss of appetite/break in weight curve/general health alteration

HPO human phenotypes related to Pseudomyxoma Peritonei:

(show all 17)
id Description Frequency HPO Source Accession
1 ascites hallmark (90%) HP:0001541
2 abnormality of the peritoneum hallmark (90%) HP:0002585
3 abnormality of the abdominal wall hallmark (90%) HP:0004298
4 inflammation of the large intestine typical (50%) HP:0002037
5 weight loss occasional (7.5%) HP:0001824
6 nausea and vomiting occasional (7.5%) HP:0002017
7 constipation occasional (7.5%) HP:0002019
8 abdominal pain occasional (7.5%) HP:0002027
9 respiratory insufficiency occasional (7.5%) HP:0002093
10 lymphadenopathy occasional (7.5%) HP:0002716
11 neoplasm of the pancreas occasional (7.5%) HP:0002894
12 intestinal obstruction occasional (7.5%) HP:0005214
13 neoplasm of the stomach occasional (7.5%) HP:0006753
14 abnormal renal physiology occasional (7.5%) HP:0012211
15 neoplasm of the colon occasional (7.5%) HP:0100273
16 ovarian neoplasm occasional (7.5%) HP:0100615
17 hernia occasional (7.5%) HP:0100790

Drugs & Therapeutics for Pseudomyxoma Peritonei

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Drug clinical trials:

Search ClinicalTrials for Pseudomyxoma Peritonei

Search NIH Clinical Center for Pseudomyxoma Peritonei

Genetic Tests for Pseudomyxoma Peritonei

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Anatomical Context for Pseudomyxoma Peritonei

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MalaCards organs/tissues related to Pseudomyxoma Peritonei:

33
Appendix, Colon, Ovary, Testes, Pancreas, Small intestine, Lung, Breast, Bone, Spleen, Kidney, Liver, Skin

Animal Models for Pseudomyxoma Peritonei or affiliated genes

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MGI Mouse Phenotypes related to Pseudomyxoma Peritonei:

37 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.2TP53, KRAS, CTNNB1, APC
2MP:00020068.8TP53, APC, MUC2, KRAS, CDX2, CDH1
3MP:00053718.8TP53, APC, KRAS, CTNNB1, CDX2
4MP:00053798.7CDH1, APC, TP53, MUC2, KRAS, CTNNB1
5MP:00053698.7TP53, VIM, KRAS, CDH2, CTNNB1, APC
6MP:00107718.7KRAS, TP53, F2, CDH1, CTNNB1, APC
7MP:00028738.5CTNNB1, CDH1, KRAS, TP53, APC, F2
8MP:00053898.4VIM, F2, CTNNB1, APC, TP53, KRAS
9MP:00053818.2KRAS, CDH1, F2, CDX2, TP53, MUC2
10MP:00053808.2F2, APC, TP53, VIM, KRAS, CDH1
11MP:00053858.0MUC2, CTNNB1, CDH2, CDH1, CDX2, F2
12MP:00053877.9F2, APC, VIM, TP53, MUC2, MUC5AC
13MP:00053787.9CDH1, F2, APC, TP53, VIM, MUC2
14MP:00107687.8CDH1, CTNNB1, TP53, VIM, MUC2, KRAS
15MP:00053767.5F2, MUC2, APC, MUC5AC, KRAS, CDX2
16MP:00053847.5KRT7, CDX2, CDH2, CDH1, VIM, MUC2

Publications for Pseudomyxoma Peritonei

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Articles related to Pseudomyxoma Peritonei:

(show top 50)    (show all 515)
idTitleAuthorsYear
1
A rare cause of ascites: pseudomyxoma peritonei and a review of the literature. (25838904)
2015
2
Multicentre study of the learning curve and surgical performance of cytoreductive surgery with intraperitoneal chemotherapy for pseudomyxoma peritonei. (25329419)
2014
3
Appendiceal mucocele and pseudomyxoma peritonei; the clinical boundaries of a subtle disease. (25163976)
2014
4
Kras mutations and p53 overexpression in pseudomyxoma peritonei: association with phenotype and prognosis. (23199549)
2013
5
Aggressive pseudomyxoma peritonei: a case report with an unusual clinical presentation. (24324903)
2013
6
Role of preoperative sonography in the diagnosis and pathologic staging of pseudomyxoma peritonei. (23980216)
2013
7
Potential mucolytic agents for mucinous ascites from pseudomyxoma peritonei. (22359216)
2012
8
Pseudomyxoma peritonei (mucinous carcinoma peritonei) preceded by intraductal papillary neoplasm of the bile duct. (22406366)
2012
9
Mucolysis by ascorbic acid and hydrogen peroxide on compact mucin secreted in pseudomyxoma peritonei. (22261589)
2012
10
Evaluation of complete cytoreductive surgery and two intraperitoneal chemotherapy techniques in Pseudomyxoma peritonei. (22763244)
2012
11
Early- and long-term outcome data of patients with pseudomyxoma peritonei from appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. (22614976)
2012
12
Extraperitoneal presentation of pseudomyxoma peritonei as retroperitoneal invasion with skin fistula-a case report. (22202264)
2011
13
Commentary on 'Survival of patients with pseudomyxoma peritonei treated by serial debulking'. (20718839)
2010
14
Re: JSLS. 2009;13(2):203-206 Laparoscopic mucin removal in patients with pseudomyxoma peritonei. (20529543)
2010
15
Presumed fungal retinitis associated with pseudomyxoma peritonei. (21686849)
2009
16
Tailgut cyst, an unusual cause of pseudomyxoma peritonei. (19856666)
2009
17
Incidental finding of pseudomyxoma peritonei at primary cesarean section. (19399708)
2009
18
Chemo-hyperthermic peritoneal perfusion (CHPP) for appendiceal pseudomyxoma peritonei. (19390942)
2009
19
Adenocarcinoma of urachal cyst associated with pseudomyxoma peritonei masquerading as abdominal tuberculosis: A case report and review of literature. (19468408)
2008
20
Low-grade mucinous epithelial neoplasm (intestinal type) arising in a mature sacrococcygeal teratoma with late recurrence as pseudomyxoma peritonei. (18289636)
2008
21
Re: An evidence-based approach: Sugarbaker protocol and pseudomyxoma peritonei of appendiceal origin. (18959716)
2008
22
A phase II study evaluating the use of concurrent mitomycin C and capecitabine in patients with advanced unresectable pseudomyxoma peritonei. (18682713)
2008
23
Incidental finding of pseudomyxoma peritonei in a deceased organ donor: implications on organ donation. (17239029)
2007
24
Pseudomyxoma peritonei presenting with femoral hernias and peritonitis. (17508254)
2007
25
How safe and effective is surgery with intraperitoneal chemotherapy for pseudomyxoma peritonei? (17667901)
2007
26
Toxicity and mortality of cytoreduction and intraoperative hyperthermic intraperitoneal chemotherapy in pseudomyxoma peritonei--a report of 103 procedures. (16303281)
2006
27
Pseudomyxoma peritonei: A rose by any other name... (17063093)
2006
28
The etiology, clinical presentation, and management of pseudomyxoma peritonei. (14567019)
2003
29
Successful treatment of pseudomyxoma peritonei with intraperitoneal 10 per cent dextrose, sizofiran and cisplatin. (12521714)
2002
30
The subpyloric space: an important surgical and radiologic feature in pseudomyxoma peritonei. (12099657)
2002
31
Extensive surgical cytoreduction and intraoperative hyperthermic intraperitoneal chemotherapy in patients with pseudomyxoma peritonei (Br J Surg 2001; 88: 458-63). (11488802)
2001
32
Use of ultrasonic surgical aspirator in operative cytoreduction of pseudomyxoma peritonei. (10789759)
2000
33
Pseudomyxoma peritonei in the pleural cavity: report of a case. (10211530)
1999
34
Pseudomyxoma peritonei. (9660531)
1998
35
Pseudomyxoma peritonei: a report of eight cases. (7829144)
1994
36
Pseudomyxoma peritonei with progressive calcifications: CT findings. (1544550)
1992
37
Pseudomyxoma peritonei from metastatic colloid carcinoma of the breast. (1846836)
1991
38
Pseudomyxoma peritonei--experience from a tertiary referral centre. (1930042)
1991
39
Clinical and radiological features of pseudomyxoma peritonei. (2530349)
1989
40
Pseudomyxoma peritonei--preoperative diagnosis on CT scan. A report of 2 cases. (3150267)
1988
41
Pseudomyxoma peritonei--benign or malignant. (3758624)
1986
42
Computed tomography and magnetic resonance of pseudomyxoma peritonei. (4056150)
1985
43
Successful treatment of pseudomyxoma peritonei of ovarian origin with cis-platinum, doxorubicin, and cyclophosphamide. (4054721)
1985
44
Pseudomyxoma peritonei associated with mucinous adenocarcinoma of the pancreas: CT findings and CT-guided biopsy. (6323557)
1984
45
Pseudomyxoma peritonei of ovarian origin--an autopsy case. (161472)
1979
46
Pseudomyxoma peritonei. (4645609)
1972
47
Pseudomyxoma peritonei. New concepts in management with a report of seventeen patients. (5773930)
1969
48
Bluish translucent umbilical lesions of pseudomyxoma peritonei. (6046394)
1967
49
Pseudomyxoma peritonei due to mucocele of the appendix. A report of four cases and review of the literature. (13777126)
1961
50
Pseudomyxoma peritonei. (13655140)
1959

Variations for Pseudomyxoma Peritonei

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Cosmic variations for Pseudomyxoma Peritonei:

8
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
1521KRASperitoneum,appendix,other,pseudomyxoma peritonei1

Expression for genes affiliated with Pseudomyxoma Peritonei

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Search GEO for disease gene expression data for Pseudomyxoma Peritonei.

Pathways for genes affiliated with Pseudomyxoma Peritonei

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Pathways related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

(show all 39)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.9CDX2, CTNNB1
29.6CDH1, CDX2, TP53
39.6CDX2, APC, CTNNB1
49.6APC, CTNNB1, CDH2
59.6CDH1, CDH2, CTNNB1
69.6CTNNB1, CDH2, CDH1
7
Show member pathways
9.6CTNNB1, CDH2, CDH1
89.6APC, CTNNB1, CDH1
99.6CDH1, CTNNB1, APC
10
Show member pathways
RAC1 signaling pathway38
9.6CDH1, APC, CTNNB1
119.6CTNNB1, CDH1, APC
129.5CDH2, VIM, CTNNB1
139.5TP53, CTNNB1, KRAS
14
Show member pathways
9.5CTNNB1, KRAS, TP53
159.5APC, TP53, CTNNB1
16
Show member pathways
DNA damage response (only ATM dependent)38
Wnt Signaling Pathway and Pluripotency38
9.5CTNNB1, APC, TP53
179.5CDH1, TP53, CTNNB1
18
Show member pathways
9.4MUC5AC, MUC2, MUC6, MUC5B
19
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways60
Immune response IL 1 signaling pathway60
9.4KRAS, MUC5AC, MUC5B, MUC2
209.3TP53, KRAS, VIM, APC
219.3CDH1, APC, CDH2, CTNNB1
229.3TP53, KRAS, CTNNB1, APC
239.3APC, CTNNB1, KRAS, TP53
24
Show member pathways
9.3KRAS, CTNNB1, TP53, APC
259.2TP53, CTNNB1, KRAS, CDH1
269.2KRAS, CDH1, TP53, CTNNB1
27
Show member pathways
Signaling Pathways in Glioblastoma38
9.2KRAS, TP53, CTNNB1, CDH1
28
Show member pathways
9.2APC, VIM, CDH1, CTNNB1
299.2APC, CTNNB1, TP53, CDH1
30
Show member pathways
Wnt Signaling Pathway NetPath38
9.2CTNNB1, CDH1, TP53, APC
319.0CDH1, CEACAM5, CTNNB1, CDH2
329.0F2, CDH2, CDH1, APC, CTNNB1
33
Show member pathways
9.0APC, VIM, CDH1, CDH2, CTNNB1
34
Show member pathways
Signal transduction PTEN pathway60
9.0APC, CTNNB1, CDH1, KRAS, TP53
359.0CTNNB1, KRAS, CDH1, TP53, APC
36
Show member pathways
Proteasome Degradation38
Immune response Antigen presentation by MHC class I60
8.9VIM, CDH1, TP53, APC, CTNNB1
37
Show member pathways
8.6CDH1, VIM, APC, CDH2, CTNNB1, TP53
388.6CDH1, APC, TP53, CTNNB1, CDH2, VIM
39
Show member pathways
8.5CDX2, MUC5AC, MUC6, CTNNB1, MUC5B, MUC2

Compounds for genes affiliated with Pseudomyxoma Peritonei

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Compounds related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

(show top 50)    (show all 115)
idCompoundScoreTop Affiliating Genes
1exisulind459.8APC, CDH1, CTNNB1
2sodium bisulfite459.8CDH1, CTNNB1, APC
3aristolochic acid45 310.7TP53, CDH1, VIM
4o6-methylguanine459.7TP53, APC, CDH1, KRAS
5dicoumarol459.6TP53, F2, MUC5AC
6sulindac45 1310.5CTNNB1, APC, TP53, CDH1
75-methylcytosine45 2610.5APC, TP53, CDH1
8irinotecan45 51 1311.3TP53, CEACAM5, KRAS, CDH1
9cytosine45 2610.3CEACAM5, PSG2, CDH1, APC
10latex459.3CDH1, PSG2, CDH2, CEACAM5
11nocodazole45 1310.3VIM, CTNNB1, CDH1, TP53, APC
12p002459.2CDH1, CTNNB1, KRAS, PSG2, CEACAM5
13vitamin d459.1APC, CDH1, CTNNB1, CDX2, KRAS, VIM
14matrigel459.1CTNNB1, VIM, KRT7, CDH1, CDH2
15tamoxifen45 51 30 1312.0F2, TP53, VIM, CDH1, CTNNB1
16rapamycin459.0KRAS, VIM, APC, CTNNB1, CDH1
17n acetylcysteine459.0CDH1, MUC5AC, CTNNB1, F2, TP53
18carbohydrates458.9CDH1, CEACAM5, MUC5AC, MUC2, KRT7
19sb 20358045 619.9TP53, MUC5AC, VIM, MUC2, CDH1, CTNNB1
20methotrexate51 45 1310.9MUC2, VIM, KRT7, CDH1, MUC5AC, F2
21adriamycin458.8TP53, VIM, CDH1, CTNNB1, PSG2, CEACAM5
22crcs458.7CTNNB1, CDH1, APC, TP53, MUC2, CEACAM5
23formaldehyde45 269.7CDH1, VIM, KRT20, KRT7, PSG2
24retinoid458.7CDH1, MUC5AC, VIM, TP53, KRT7, CTNNB1
25paclitaxel45 51 1310.6CTNNB1, CDH1, KRAS, TP53, VIM
26polysaccharide458.6CTNNB1, CEACAM5, KRT7, MUC6, CDH2, MUC5AC
27sialic acid458.6PSG2, KRT7, CDH1, CEACAM5, MUC2, CDH2
28hyaluronic acid45 269.5CDH1, KRT20, CEACAM5, VIM, F2
29gefitinib45 51 1310.5KRAS, CDH1, CEACAM7, CTNNB1, CEACAM5, VIM
30thymidine45 269.5CEACAM7, PSG2, TP53, CEACAM5, CTNNB1, CDX2
31phosphatidylinositol458.4MUC5AC, APC, CEACAM5, KRAS, CDH1, CTNNB1
32cysteine458.3CTNNB1, MUC5AC, MUC2, CEACAM5, CDX2, CDH1
335-aza-2deoxycytidine458.2KRT7, CDX2, CDH1, CDH2, CTNNB1, MUC2
34glycogen45 269.2PSG2, CDH1, CDH2, KRT7, CEACAM5, VIM
35glucose458.2MUC2, CDH2, KRT7, PSG2, CEACAM5, MUC5AC
36mucicarmine458.2KRT20, KRT7, CEACAM7, CEACAM5, VIM
37oligonucleotide458.1CDH2, VIM, MUC2, MUC5AC, TP53, APC
38doxorubicin45 51 1310.0TP53, CEACAM5, KRT20, PSG2, VIM, CTNNB1
39serine457.9CTNNB1, CDH1, KRAS, CDH2, MUC2, MUC5AC
40butyrate457.8TP53, CDH1, VIM, CDX2, CEACAM7, KRAS
41hematoxylin457.7VIM, MUC2, MUC5AC, CEACAM5, PSG2, KRT7
42testosterone45 61 26 1310.7KRT7, APC, VIM, MUC5AC, CTNNB1, CDH2
435fluorouracil457.5TP53, MUC2, MUC5AC, CEACAM5, CEACAM7, PSG2
44b 723457.4CDH2, CDH1, KRT20, VIM, CEACAM5, KRT7
45retinoic acid45 268.1MUC2, CEACAM7, VIM, KRAS, KRT7, CDH1
46vegf457.1KRT20, TP53, CTNNB1, CEACAM5, PSG2, KRAS
47tyrosine457.0CTNNB1, APC, KRT20, CDH2, MUC5AC, CEACAM5
48paraffin455.8KRT7, KRAS, PSG2, CEACAM5, MUC5AC, MUC6
49progesterone45 30 61 26 139.6CTNNB1, CDH2, CDH1, CDX2, KRT20, KRT7
50estrogen455.1KRAS, CTNNB1, CDH1, CDX2, KRT20, KRT7

GO Terms for genes affiliated with Pseudomyxoma Peritonei

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Cellular components related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1beta-catenin destruction complexGO:00308779.9CTNNB1, APC
2fascia adherensGO:00059169.9CTNNB1, CDH2
3catenin complexGO:00163429.7CDH1, CDH2, CTNNB1
4lateral plasma membraneGO:00163289.7CTNNB1, CDH1, APC
5cell-cell adherens junctionGO:00059139.5APC, CDH1, CDH2, CTNNB1
6lamellipodiumGO:00300279.5CTNNB1, CDH2, APC
7Golgi lumenGO:00057969.3MUC5AC, MUC6, MUC5B, MUC2, F2
8basolateral plasma membraneGO:00163239.3CTNNB1, CDH1, CEACAM5
9intermediate filamentGO:00058828.9VIM, KRT7, KRT20
10extracellular regionGO:00055768.4F2, MUC5B, MUC6, REG4, PSG2, CDH1

Biological processes related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1maintenance of gastrointestinal epitheliumGO:003027710.1MUC2, MUC6
2regulation of protein localization to cell surfaceGO:0200000810.1CDH1, CTNNB1
3canonical Wnt signaling pathway involved in negative regulation of apoptotic processGO:004433610.1CTNNB1, APC
4cellular response to indole-3-methanolGO:007168110.0CDH1, CTNNB1
5striated muscle cell differentiationGO:005114610.0CDH2, KRAS
6proximal/distal pattern formationGO:00099549.8CTNNB1, APC
7negative regulation of canonical Wnt signaling pathwayGO:00900909.8CDH2, CDH1, APC
8T cell differentiation in thymusGO:00330779.7CTNNB1, APC, TP53
9O-glycan processingGO:00162669.7MUC5AC, MUC6, MUC5B, MUC2
10trophectodermal cell differentiationGO:00018299.7CDX2, CDH1
11cell migrationGO:00164779.6PSG2, APC, CDH2
12cellular component disassembly involved in execution phase of apoptosisGO:00069219.5APC, VIM, CDH1, CTNNB1
13intermediate filament organizationGO:00451099.4VIM, KRT20
14post-translational protein modificationGO:00436879.4F2, MUC2, MUC5B, MUC6, MUC5AC
15cellular protein metabolic processGO:00442679.3F2, MUC2, MUC5B, MUC6, MUC5AC
16apoptotic processGO:00069158.3TP53, APC, CTNNB1, VIM, KRT20, CDH1

Molecular functions related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1alpha-catenin bindingGO:00452949.8CTNNB1, CDH2
2gamma-catenin bindingGO:00452959.7APC, CDH2, CDH1
3beta-catenin bindingGO:00080139.4APC, CDH1, CDH2
4protein phosphatase bindingGO:00199039.3CDH2, CTNNB1, TP53, CDH1
5protein bindingGO:00055156.3CTNNB1, F2, APC, TP53, CDH2, CDH1

Products for genes affiliated with Pseudomyxoma Peritonei

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Sources for Pseudomyxoma Peritonei

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet