PMP
MCID: PSD007
MIFTS: 67

Pseudomyxoma Peritonei (PMP) malady

Rare diseases, Cancer diseases categories

Summaries for Pseudomyxoma Peritonei

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44NIH Rare Diseases, 66Wikipedia, 34MalaCards
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NIH Rare Diseases:44 Pseudomyxoma peritonei is a tumor that most often begins in the appendix.  as the tumor grows, tumor cells may spread into the peritoneal cavity and land on other nearby organs (such as the ovaries or intestines), sometimes forming additional tumors on the surface of these organs.  pseudomyxoma peritonei is extremely unlikely to grow into these organs (to become invasive) or spread to more distant parts of the body (metastasize); therefore, it is not usually thought of as a malignant tumor.  it is rare, occurring in approximately two out of a million people, and women are affected two to three times more frequently than men.  the first symptoms of pseudomyxoma peritonei are an increase in the size of the belly, appendicitis, or the finding of a mass on the ovary during medical imaging tests.   last updated: 9/27/2011

MalaCards: Pseudomyxoma Peritonei, also known as PMP, is related to cystadenocarcinoma and mucinous cystadenocarcinoma, and has symptoms including peritoneal diseases, anomalies of the abdominal wall and lymphadenopathy/polyadenopathies. An important gene associated with Pseudomyxoma Peritonei is MUC2 (mucin 2, oligomeric mucus/gel-forming), and among its related pathways are Incretin Synthesis, Secretion, and Inactivation and Selected targets of Oct 3 4. The compounds exisulind and sodium bisulfite have been mentioned in the context of this disorder. Affiliated tissues include appendix, ovary and colon, and related mouse phenotypes are pigmentation and tumorigenesis.

Wikipedia:66 Pseudomyxoma peritonea is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that... more...

Aliases & Classifications for Pseudomyxoma Peritonei

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Sources:
9Disease Ontology, 44NIH Rare Diseases, 11DISEASES, 46Novoseek, 50Orphanet, 63UMLS, 41NCIt, 59SNOMED-CT, 36MeSH, 37MESH via Orphanet, 27ICD10 via Orphanet, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Orphanet: 50 
Rare tumors


Characteristics (Orphanet epidemiological data):

50
pseudomyxoma peritonei:
Age of onset: Adulthood; Age of death: Any age


Aliases & Descriptions:

pseudomyxoma peritonei 9 44 11 46 50 63
pmp 44 50
syndrome of pseudomyxoma peritonei 44
gelatinous ascites 50
mucinous ascites 9
adenomucinosis 50


External Ids:

Disease Ontology9 DOID:3559
NCIt41 C3345
MeSH36 D011553
MESH via Orphanet37 D011553
ICD10 via Orphanet27 C78.6
SNOMED-CT via Orphanet60 112679004, 307601000
UMLS via Orphanet64 C0033822

Related Diseases for Pseudomyxoma Peritonei

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18GeneCards, 19GeneDecks
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Diseases related to Pseudomyxoma Peritonei via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 153)
idRelated DiseaseScoreTop Affiliating Genes
1cystadenocarcinoma31.3CEACAM5, MUC5AC, MUC2
2mucinous cystadenocarcinoma31.2KRT20, KRT7, CEACAM7
3cystadenoma31.0KRT7, KRAS
4adenocarcinoma30.7CTNNB1, CDH2, CDH1, CDX2, KRT20, KRT7
5villous adenoma30.5MUC5AC, APC
6breast cancer30.3CTNNB1, CDH1, KRAS, APC
7ovarian cancer30.1CTNNB1, CDH2, CDH1, KRT7, KRAS, PSG2
8adenoma30.0CTNNB1, CDH2, CDH1, CDX2, KRT20, KRT7
9colorectal cancer29.9CTNNB1, CDH1, CDX2, KRT20, KRT7, KRAS
10melanoma29.7CTNNB1, CDH2, CDH1, CDX2, KRAS, PSG2
11peritonitis10.9
12mucinous adenocarcinoma10.9
13teratoma10.7
14cystic teratoma10.6
15mucinous adenocarcinoma of the appendix10.6
16endometriosis10.5
17peritoneal mesothelioma10.5
18appendiceal neoplasm10.5
19ovarian mucinous cystadenocarcinoma10.4
20hepatitis10.4
21intestinal obstruction10.4
22gelatinous ascites10.4
23urachal cyst10.4
24neurofibromatosis10.2
25malignant peritoneal mesothelioma10.2
26acute pancreatitis10.2
27pyometritis10.2
28melioidosis10.2
29acromegaly10.2
30colloid carcinoma of the pancreas10.2
31appendicitis10.2
32infertility10.2
33abdominal tuberculosis10.2
34cervicitis10.2
35dermatomyositis10.2
36hyperglycemia10.2
37mature teratoma10.2
38ovarian cyst10.2
39ovarian cystadenocarcinoma10.2
40pancreatitis10.2
41retinitis10.2
42tuberculosis10.2
43cerebellar degeneration10.2
44paraneoplastic cerebellar degeneration10.2
45sacrococcygeal teratoma10.2
46ampulla of vater carcinoma10.1MUC2
47bladder adenocarcinoma10.1CDX2
48metanephric adenoma10.1KRT7
49inverted papilloma10.1KRT20
50intestinal neoplasm10.1APC

Graphical network of the top 20 diseases related to Pseudomyxoma Peritonei:



Diseases related to pseudomyxoma peritonei

Symptoms for Pseudomyxoma Peritonei

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50Orphanet
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Symptoms:

50 (show all 19)
  • peritoneal diseases
  • anomalies of the abdominal wall
  • lymphadenopathy/polyadenopathies
  • estomach/gastric neoplasm/tumor/carcinoma/cancer
  • pancreatic/pancreas neoplasm/tumor/carcinoma/cancer
  • constipation
  • pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • early death/lethality
  • ascitis
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • herniae
  • acute abdominal pain/colic
  • intestinal obstruction/ileus
  • colon neoplasm/tumor/carcinoma/cancer
  • inflammatory intestinal disease
  • ovary/fallopian tube neoplasm/tumor/carcinoma/cancer (excl. teratoma/germinoma)
  • digestive neoplasm/tumor/carcinoma/cancer
  • nausea/vomiting/regurgitation/merycism/hyperemesis

Drugs & Therapeutics for Pseudomyxoma Peritonei

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Pseudomyxoma Peritonei

Drug clinical trials:

Search ClinicalTrials for Pseudomyxoma Peritonei

Search NIH Clinical Center for Pseudomyxoma Peritonei

Search CenterWatch for Pseudomyxoma Peritonei

Genetic Tests for Pseudomyxoma Peritonei

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Anatomical Context for Pseudomyxoma Peritonei

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34MalaCards
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MalaCards organs/tissues related to Pseudomyxoma Peritonei:

34
Appendix, Ovary, Colon, Testes, Small intestine, Pancreas, Lung, Breast, Spleen, Skin, Liver, Kidney

Animal Models for Pseudomyxoma Peritonei or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Pseudomyxoma Peritonei:

38 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.2TP53, KRAS, CTNNB1, APC
2MP:00020068.8TP53, APC, MUC2, KRAS, CDX2, CDH1
3MP:00053718.8TP53, APC, KRAS, CTNNB1, CDX2
4MP:00053798.7CDH1, APC, TP53, MUC2, KRAS, CTNNB1
5MP:00053698.7TP53, VIM, KRAS, CDH2, CTNNB1, APC
6MP:00107718.7KRAS, TP53, F2, CDH1, CTNNB1, APC
7MP:00028738.5CTNNB1, CDH1, KRAS, TP53, APC, F2
8MP:00053898.4VIM, F2, CTNNB1, APC, TP53, KRAS
9MP:00053818.2KRAS, CDH1, F2, CDX2, TP53, MUC2
10MP:00053808.2F2, APC, TP53, VIM, KRAS, CDH1
11MP:00053858.0MUC2, CTNNB1, CDH2, CDH1, CDX2, F2
12MP:00053877.9F2, APC, VIM, TP53, MUC2, MUC5AC
13MP:00053787.9CDH1, F2, APC, TP53, VIM, MUC2
14MP:00107687.8CDH1, CTNNB1, TP53, VIM, MUC2, KRAS
15MP:00053767.5F2, MUC2, APC, MUC5AC, KRAS, CDX2
16MP:00053847.5KRT7, CDX2, CDH2, CDH1, VIM, MUC2

Publications for Pseudomyxoma Peritonei

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53PubMed
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Articles related to Pseudomyxoma Peritonei:

(show top 50)    (show all 490)
idTitleAuthorsYear
1
Kras mutations and p53 overexpression in pseudomyxoma peritonei: association with phenotype and prognosis. (23199549)
2013
2
Aggressive pseudomyxoma peritonei: a case report with an unusual clinical presentation. (24324903)
2013
3
Role of preoperative sonography in the diagnosis and pathologic staging of pseudomyxoma peritonei. (23980216)
2013
4
Potential mucolytic agents for mucinous ascites from pseudomyxoma peritonei. (22359216)
2012
5
Pseudomyxoma peritonei (mucinous carcinoma peritonei) preceded by intraductal papillary neoplasm of the bile duct. (22406366)
2012
6
Mucolysis by ascorbic acid and hydrogen peroxide on compact mucin secreted in pseudomyxoma peritonei. (22261589)
2012
7
Evaluation of complete cytoreductive surgery and two intraperitoneal chemotherapy techniques in Pseudomyxoma peritonei. (22763244)
2012
8
Early- and long-term outcome data of patients with pseudomyxoma peritonei from appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. (22614976)
2012
9
Extraperitoneal presentation of pseudomyxoma peritonei as retroperitoneal invasion with skin fistula-a case report. (22202264)
2011
10
Commentary on 'Survival of patients with pseudomyxoma peritonei treated by serial debulking'. (20718839)
2010
11
Re: JSLS. 2009;13(2):203-206 Laparoscopic mucin removal in patients with pseudomyxoma peritonei. (20529543)
2010
12
Presumed fungal retinitis associated with pseudomyxoma peritonei. (21686849)
2009
13
Tailgut cyst, an unusual cause of pseudomyxoma peritonei. (19856666)
2009
14
Incidental finding of pseudomyxoma peritonei at primary cesarean section. (19399708)
2009
15
Chemo-hyperthermic peritoneal perfusion (CHPP) for appendiceal pseudomyxoma peritonei. (19390942)
2009
16
Adenocarcinoma of urachal cyst associated with pseudomyxoma peritonei masquerading as abdominal tuberculosis: A case report and review of literature. (19468408)
2008
17
Low-grade mucinous epithelial neoplasm (intestinal type) arising in a mature sacrococcygeal teratoma with late recurrence as pseudomyxoma peritonei. (18289636)
2008
18
Re: An evidence-based approach: Sugarbaker protocol and pseudomyxoma peritonei of appendiceal origin. (18959716)
2008
19
A phase II study evaluating the use of concurrent mitomycin C and capecitabine in patients with advanced unresectable pseudomyxoma peritonei. (18682713)
2008
20
Incidental finding of pseudomyxoma peritonei in a deceased organ donor: implications on organ donation. (17239029)
2007
21
Pseudomyxoma peritonei presenting with femoral hernias and peritonitis. (17508254)
2007
22
How safe and effective is surgery with intraperitoneal chemotherapy for pseudomyxoma peritonei? (17667901)
2007
23
Toxicity and mortality of cytoreduction and intraoperative hyperthermic intraperitoneal chemotherapy in pseudomyxoma peritonei--a report of 103 procedures. (16303281)
2006
24
Pseudomyxoma peritonei: A rose by any other name... (17063093)
2006
25
Ten years experience in the treatment of pseudomyxoma peritonei by cytoreduction, peritonectomy and semi-closed hyperthermic antiblastic peritoneal perfusion. (17203755)
2006
26
The etiology, clinical presentation, and management of pseudomyxoma peritonei. (14567019)
2003
27
Successful treatment of pseudomyxoma peritonei with intraperitoneal 10 per cent dextrose, sizofiran and cisplatin. (12521714)
2002
28
The subpyloric space: an important surgical and radiologic feature in pseudomyxoma peritonei. (12099657)
2002
29
Extensive surgical cytoreduction and intraoperative hyperthermic intraperitoneal chemotherapy in patients with pseudomyxoma peritonei (Br J Surg 2001; 88: 458-63). (11488802)
2001
30
Use of ultrasonic surgical aspirator in operative cytoreduction of pseudomyxoma peritonei. (10789759)
2000
31
Pseudomyxoma peritonei in the pleural cavity: report of a case. (10211530)
1999
32
Pseudomyxoma peritonei. (9660531)
1998
33
Pseudomyxoma peritonei: a report of eight cases. (7829144)
1994
34
Pseudomyxoma peritonei with progressive calcifications: CT findings. (1544550)
1992
35
Pseudomyxoma peritonei from metastatic colloid carcinoma of the breast. (1846836)
1991
36
Pseudomyxoma peritonei--experience from a tertiary referral centre. (1930042)
1991
37
Clinical and radiological features of pseudomyxoma peritonei. (2530349)
1989
38
Abdominal plexiform neurofibromatosis simulating pseudomyxoma peritonei on computed tomography. (2501362)
1989
39
Pseudomyxoma peritonei--preoperative diagnosis on CT scan. A report of 2 cases. (3150267)
1988
40
Pseudomyxoma peritonei--benign or malignant. (3758624)
1986
41
Computed tomography and magnetic resonance of pseudomyxoma peritonei. (4056150)
1985
42
Successful treatment of pseudomyxoma peritonei of ovarian origin with cis-platinum, doxorubicin, and cyclophosphamide. (4054721)
1985
43
Pseudomyxoma peritonei associated with mucinous adenocarcinoma of the pancreas: CT findings and CT-guided biopsy. (6323557)
1984
44
Pseudomyxoma peritonei of ovarian origin--an autopsy case. (161472)
1979
45
Pseudomyxoma peritonei. (4645609)
1972
46
Pseudomyxoma peritonei. New concepts in management with a report of seventeen patients. (5773930)
1969
47
Bluish translucent umbilical lesions of pseudomyxoma peritonei. (6046394)
1967
48
"MUCOCELE APPENDICIS" WITH PSEUDOMYXOMA PERITONEI AND PULMONARY METASTASES. (14154710)
1964
49
Pseudomyxoma peritonei due to mucocele of the appendix. A report of four cases and review of the literature. (13777126)
1961
50
Pseudomyxoma peritonei. (13655140)
1959

Variations for Pseudomyxoma Peritonei

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Expression for genes affiliated with Pseudomyxoma Peritonei

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pseudomyxoma Peritonei

Search GEO for disease gene expression data for Pseudomyxoma Peritonei.

Pathways for genes affiliated with Pseudomyxoma Peritonei

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Sources:
51PathCards, 56Reactome, 13EMD Millipore, 5Cell Signaling Technology, 39NCBI BioSystems Database, 61Thomson Reuters, 31KEGG, 62Tocris Bioscience, 54QIAGEN, 58SinoBiological, 55R&D Systems
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Pathways related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

(show all 39)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.9CDX2, CTNNB1
29.6CDH1, CDX2, TP53
39.6CDX2, APC, CTNNB1
49.6APC, CTNNB1, CDH2
59.6CDH1, CDH2, CTNNB1
69.6CTNNB1, CDH2, CDH1
7
Show member pathways
9.6CTNNB1, CDH2, CDH1
89.6APC, CTNNB1, CDH1
99.6CDH1, CTNNB1, APC
10
Show member pathways
RAC1 signaling pathway39
9.6CDH1, APC, CTNNB1
119.6CTNNB1, CDH1, APC
129.5CDH2, VIM, CTNNB1
139.5TP53, CTNNB1, KRAS
14
Show member pathways
9.5CTNNB1, KRAS, TP53
159.5APC, TP53, CTNNB1
16
Show member pathways
DNA damage response (only ATM dependent)39
Wnt Signaling Pathway and Pluripotency39
9.5CTNNB1, APC, TP53
179.5CDH1, TP53, CTNNB1
18
Show member pathways
9.4MUC5AC, MUC2, MUC6, MUC5B
19
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways61
Immune response IL 1 signaling pathway61
9.4KRAS, MUC5AC, MUC5B, MUC2
209.3TP53, KRAS, VIM, APC
219.3CDH1, APC, CDH2, CTNNB1
229.3TP53, KRAS, CTNNB1, APC
239.3APC, CTNNB1, KRAS, TP53
24
Show member pathways
9.3KRAS, CTNNB1, TP53, APC
259.2TP53, CTNNB1, KRAS, CDH1
269.2KRAS, CDH1, TP53, CTNNB1
27
Show member pathways
Signaling Pathways in Glioblastoma39
9.2KRAS, TP53, CTNNB1, CDH1
28
Show member pathways
9.2APC, VIM, CDH1, CTNNB1
299.2APC, CTNNB1, TP53, CDH1
30
Show member pathways
Wnt Signaling Pathway NetPath39
9.2CTNNB1, CDH1, TP53, APC
319.0CDH1, CEACAM5, CTNNB1, CDH2
329.0F2, CDH2, CDH1, APC, CTNNB1
33
Show member pathways
9.0APC, VIM, CDH1, CDH2, CTNNB1
34
Show member pathways
Signal transduction PTEN pathway61
9.0APC, CTNNB1, CDH1, KRAS, TP53
359.0CTNNB1, KRAS, CDH1, TP53, APC
36
Show member pathways
Proteasome Degradation39
Immune response Antigen presentation by MHC class I61
8.9VIM, CDH1, TP53, APC, CTNNB1
37
Show member pathways
8.6CDH1, VIM, APC, CDH2, CTNNB1, TP53
388.6CDH1, APC, TP53, CTNNB1, CDH2, VIM
39
Show member pathways
8.5CDX2, MUC5AC, MUC6, CTNNB1, MUC5B, MUC2

Compounds for genes affiliated with Pseudomyxoma Peritonei

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Sources:
46Novoseek, 3BitterDB, 12DrugBank, 25HMDB, 52PharmGKB, 30IUPHAR, 62Tocris Bioscience
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Compounds related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

(show top 50)    (show all 115)
idCompoundScoreTop Affiliating Genes
1exisulind469.8APC, CDH1, CTNNB1
2sodium bisulfite469.8CDH1, CTNNB1, APC
3aristolochic acid46 310.7TP53, CDH1, VIM
4o6-methylguanine469.7TP53, APC, CDH1, KRAS
5dicoumarol469.6TP53, F2, MUC5AC
6sulindac46 1210.5CTNNB1, APC, TP53, CDH1
75-methylcytosine46 2510.5APC, TP53, CDH1
8irinotecan46 52 1211.3TP53, CEACAM5, KRAS, CDH1
9cytosine46 2510.3CEACAM5, PSG2, CDH1, APC
10latex469.3CDH1, PSG2, CDH2, CEACAM5
11nocodazole46 1210.3VIM, CTNNB1, CDH1, TP53, APC
12p002469.2CDH1, CTNNB1, KRAS, PSG2, CEACAM5
13vitamin d469.1APC, CDH1, CTNNB1, CDX2, KRAS, VIM
14matrigel469.1CTNNB1, VIM, KRT7, CDH1, CDH2
15tamoxifen46 52 30 1212.0F2, TP53, VIM, CDH1, CTNNB1
16rapamycin469.0KRAS, VIM, APC, CTNNB1, CDH1
17n acetylcysteine469.0CDH1, MUC5AC, CTNNB1, F2, TP53
18carbohydrates468.9CDH1, CEACAM5, MUC5AC, MUC2, KRT7
19sb 20358046 629.9TP53, MUC5AC, VIM, MUC2, CDH1, CTNNB1
20methotrexate52 46 1210.9MUC2, VIM, KRT7, CDH1, MUC5AC, F2
21adriamycin468.8TP53, VIM, CDH1, CTNNB1, PSG2, CEACAM5
22crcs468.7CTNNB1, CDH1, APC, TP53, MUC2, CEACAM5
23formaldehyde46 259.7CDH1, VIM, KRT20, KRT7, PSG2
24retinoid468.7CDH1, MUC5AC, VIM, TP53, KRT7, CTNNB1
25paclitaxel46 52 1210.6CTNNB1, CDH1, KRAS, TP53, VIM
26polysaccharide468.6CTNNB1, CEACAM5, KRT7, MUC6, CDH2, MUC5AC
27sialic acid468.6PSG2, KRT7, CDH1, CEACAM5, MUC2, CDH2
28hyaluronic acid46 259.5CDH1, KRT20, CEACAM5, VIM, F2
29gefitinib46 52 1210.5KRAS, CDH1, CEACAM7, CTNNB1, CEACAM5, VIM
30thymidine46 259.5CEACAM7, PSG2, TP53, CEACAM5, CTNNB1, CDX2
31phosphatidylinositol468.4MUC5AC, APC, CEACAM5, KRAS, CDH1, CTNNB1
32cysteine468.3CTNNB1, MUC5AC, MUC2, CEACAM5, CDX2, CDH1
335-aza-2deoxycytidine468.2KRT7, CDX2, CDH1, CDH2, CTNNB1, MUC2
34glycogen46 259.2PSG2, CDH1, CDH2, KRT7, CEACAM5, VIM
35glucose468.2MUC2, CDH2, KRT7, PSG2, CEACAM5, MUC5AC
36mucicarmine468.2KRT20, KRT7, CEACAM7, CEACAM5, VIM
37oligonucleotide468.1CDH2, VIM, MUC2, MUC5AC, TP53, APC
38doxorubicin46 52 1210.0TP53, CEACAM5, KRT20, PSG2, VIM, CTNNB1
39serine467.9CTNNB1, CDH1, KRAS, CDH2, MUC2, MUC5AC
40butyrate467.8TP53, CDH1, VIM, CDX2, CEACAM7, KRAS
41hematoxylin467.7VIM, MUC2, MUC5AC, CEACAM5, PSG2, KRT7
42testosterone46 62 25 1210.7KRT7, APC, VIM, MUC5AC, CTNNB1, CDH2
435fluorouracil467.5TP53, MUC2, MUC5AC, CEACAM5, CEACAM7, PSG2
44b 723467.4CDH2, CDH1, KRT20, VIM, CEACAM5, KRT7
45retinoic acid46 258.1MUC2, CEACAM7, VIM, KRAS, KRT7, CDH1
46vegf467.1KRT20, TP53, CTNNB1, CEACAM5, PSG2, KRAS
47tyrosine467.0CTNNB1, APC, KRT20, CDH2, MUC5AC, CEACAM5
48paraffin465.8KRT7, KRAS, PSG2, CEACAM5, MUC5AC, MUC6
49progesterone46 30 62 25 129.6CTNNB1, CDH2, CDH1, CDX2, KRT20, KRT7
50estrogen465.1KRAS, CTNNB1, CDH1, CDX2, KRT20, KRT7

GO Terms for genes affiliated with Pseudomyxoma Peritonei

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Sources:
17Gene Ontology
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Cellular components related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1beta-catenin destruction complexGO:0308779.9CTNNB1, APC
2fascia adherensGO:0059169.9CTNNB1, CDH2
3catenin complexGO:0163429.7CDH1, CDH2, CTNNB1
4lateral plasma membraneGO:0163289.7CTNNB1, CDH1, APC
5cell-cell adherens junctionGO:0059139.5APC, CDH1, CDH2, CTNNB1
6lamellipodiumGO:0300279.5CTNNB1, CDH2, APC
7Golgi lumenGO:0057969.3MUC5AC, MUC6, MUC5B, MUC2, F2
8basolateral plasma membraneGO:0163239.3CTNNB1, CDH1, CEACAM5
9intermediate filamentGO:0058828.9VIM, KRT7, KRT20
10extracellular regionGO:0055768.4F2, MUC5B, MUC6, REG4, PSG2, CDH1

Biological processes related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1maintenance of gastrointestinal epitheliumGO:03027710.1MUC2, MUC6
2regulation of protein localization to cell surfaceGO:200000810.1CDH1, CTNNB1
3canonical Wnt signaling pathway involved in negative regulation of apoptotic processGO:04433610.1CTNNB1, APC
4cellular response to indole-3-methanolGO:07168110.0CDH1, CTNNB1
5striated muscle cell differentiationGO:05114610.0CDH2, KRAS
6proximal/distal pattern formationGO:0099549.8CTNNB1, APC
7negative regulation of canonical Wnt signaling pathwayGO:0900909.8CDH2, CDH1, APC
8T cell differentiation in thymusGO:0330779.7CTNNB1, APC, TP53
9O-glycan processingGO:0162669.7MUC5AC, MUC6, MUC5B, MUC2
10trophectodermal cell differentiationGO:0018299.7CDX2, CDH1
11cell migrationGO:0164779.6PSG2, APC, CDH2
12cellular component disassembly involved in execution phase of apoptosisGO:0069219.5APC, VIM, CDH1, CTNNB1
13intermediate filament organizationGO:0451099.4VIM, KRT20
14post-translational protein modificationGO:0436879.4F2, MUC2, MUC5B, MUC6, MUC5AC
15cellular protein metabolic processGO:0442679.3F2, MUC2, MUC5B, MUC6, MUC5AC
16apoptotic processGO:0069158.3TP53, APC, CTNNB1, VIM, KRT20, CDH1

Molecular functions related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1alpha-catenin bindingGO:0452949.8CTNNB1, CDH2
2gamma-catenin bindingGO:0452959.7APC, CDH1, CDH2
3beta-catenin bindingGO:0080139.4CDH2, CDH1, APC
4protein phosphatase bindingGO:0199039.3CTNNB1, CDH2, CDH1, TP53
5protein bindingGO:0055156.3F2, APC, TP53, VIM, MUC2, MUC5B

Products for genes affiliated with Pseudomyxoma Peritonei

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  • Antibodies
  • Proteins
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Sources for Pseudomyxoma Peritonei

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet