PMP
MCID: PSD007
MIFTS: 68

Pseudomyxoma Peritonei (PMP) malady

Rare diseases, Cancer diseases categories
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Summaries for Pseudomyxoma Peritonei

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NIH Rare Diseases:42 Pseudomyxoma peritonei is a tumor that most often begins in the appendix.  as the tumor grows, tumor cells may spread into the peritoneal cavity and land on other nearby organs (such as the ovaries or intestines), sometimes forming additional tumors on the surface of these organs.  pseudomyxoma peritonei is extremely unlikely to grow into these organs (to become invasive) or spread to more distant parts of the body (metastasize); therefore, it is not usually thought of as a malignant tumor.  it is rare, occurring in approximately two out of a million people, and women are affected two to three times more frequently than men.  the first symptoms of pseudomyxoma peritonei are an increase in the size of the belly, appendicitis, or the finding of a mass on the ovary during medical imaging tests.   last updated: 9/27/2011

MalaCards based summary: Pseudomyxoma Peritonei, also known as syndrome of pseudomyxoma peritonei, is related to cystadenocarcinoma and mucinous cystadenocarcinoma, and has symptoms including anomalies of the abdominal wall, ascitis and peritoneal diseases. An important gene associated with Pseudomyxoma Peritonei is MUC2 (mucin 2, oligomeric mucus/gel-forming), and among its related pathways are Incretin Synthesis, Secretion, and Inactivation and Selected targets of Oct 3 4. The compounds exisulind and sodium bisulfite have been mentioned in the context of this disorder. Affiliated tissues include appendix, ovary and colon, and related mouse phenotypes are pigmentation and tumorigenesis.

Disease Ontology:8 An appendix cancer that is characterized by progressive accumulation of mucus-secreting tumor cells within the abdomen and pelvis.

Wikipedia:65 Pseudomyxoma peritonea is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that... more...

Aliases & Classifications for Pseudomyxoma Peritonei

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 48Orphanet, 62UMLS, 39NCIt, 57SNOMED-CT, 34MeSH, 26ICD10 via Orphanet, 63UMLS via Orphanet, 35MESH via Orphanet
See all sources

Pseudomyxoma Peritonei, Aliases & Descriptions:

Name: Pseudomyxoma Peritonei 8 42 10 44 48 62
Syndrome of Pseudomyxoma Peritonei 42 62
Pmp 42 48
Ascites, Gelatinous 62
 
Gelatinous Ascites 48
Mucinous Ascites 8
Adenomucinosis 48


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Orphanet: 48 
Rare tumors


Characteristics (Orphanet epidemiological data):

48
pseudomyxoma peritonei:
Age of onset: Adulthood; Age of death: Any age


External Ids:

Disease Ontology8 DOID:3559
NCIt39 C3345
MeSH34 D011553
ICD10 via Orphanet26 C78.6
UMLS via Orphanet63 C0033822
MESH via Orphanet35 D011553

Related Diseases for Pseudomyxoma Peritonei

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Diseases related to Pseudomyxoma Peritonei via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 155)
idRelated DiseaseScoreTop Affiliating Genes
1cystadenocarcinoma31.8CEACAM5, MUC5AC, MUC2
2mucinous cystadenocarcinoma31.7KRT20, KRT7, CEACAM7
3cystadenoma31.4KRT7, KRAS
4villous adenoma31.0MUC5AC, APC
5breast cancer30.3CTNNB1, CDH1, KRAS, APC
6ovarian cancer29.4CTNNB1, CDH2, CDH1, KRT7, KRAS, PSG2
7adenocarcinoma28.7CTNNB1, CDH2, CDH1, CDX2, KRT20, KRT7
8melanoma28.6CTNNB1, CDH2, CDH1, CDX2, KRAS, PSG2
9colorectal cancer28.3CTNNB1, CDH1, CDX2, KRT20, KRT7, KRAS
10adenoma28.1CTNNB1, CDH2, CDH1, CDX2, KRT20, KRT7
11peritonitis11.0
12mucinous adenocarcinoma10.9
13teratoma10.7
14cystic teratoma10.7
15ampulla of vater carcinoma10.6MUC2
16mucinous adenocarcinoma of the appendix10.6
17bladder adenocarcinoma10.6CDX2
18endometriosis10.5
19metanephric adenoma10.5KRT7
20inverted papilloma10.5KRT20
21peritoneal mesothelioma10.5
22appendiceal neoplasm10.5
23intestinal neoplasm10.5APC
24papilloma10.5MUC5AC, MUC2
25hereditary diffuse gastric cancer10.4CDH1
26mammary paget's disease10.4KRT20, KRT7
27ovarian brenner tumor10.4KRT20, KRT7
28juvenile polyposis syndrome10.4APC
29pericardial effusion10.4PSG2
30adenomatoid tumor10.4VIM
31bronchogenic carcinoma10.4PSG2, CEACAM7
32papillary adenocarcinoma10.4CEACAM5, MUC2
33pleural tuberculosis10.4PSG2, CEACAM7
34hepatitis10.4
35ovarian mucinous cystadenocarcinoma10.4
36intestinal obstruction10.4
37gelatinous ascites10.4
38urachal cyst10.4
39cutaneous paget's disease10.4KRT20, KRT7, CEACAM7
40endodermal sinus tumor10.4KRT7, CEACAM5
41lung squamous cell carcinoma10.4PSG2, CEACAM5
42papillary craniopharyngioma10.3CTNNB1, KRT7
43stomach cancer10.3KRAS, APC
44biliary papillomatosis10.3MUC6, MUC5B, MUC2
45neuroendocrine tumor10.3CDX2, KRT20, PSG2
46gastrointestinal carcinoma10.3KRT20, CEACAM7, CEACAM5
47gastric cancer, somatic10.3KRAS, APC
48acinar cell carcinoma10.3CTNNB1, KRT7
49meningioma10.3PSG2, VIM
50turcot syndrome10.3CTNNB1, APC

Graphical network of the top 20 diseases related to Pseudomyxoma Peritonei:



Diseases related to pseudomyxoma peritonei

Symptoms for Pseudomyxoma Peritonei

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Symptoms:

48 (show all 19)
  • anomalies of the abdominal wall
  • ascitis
  • peritoneal diseases
  • inflammatory intestinal disease
  • herniae
  • nausea/vomiting/regurgitation/merycism/hyperemesis
  • acute abdominal pain/colic
  • constipation
  • intestinal obstruction/ileus
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • lymphadenopathy/polyadenopathies
  • pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria
  • digestive neoplasm/tumor/carcinoma/cancer
  • estomach/gastric neoplasm/tumor/carcinoma/cancer
  • colon neoplasm/tumor/carcinoma/cancer
  • pancreatic/pancreas neoplasm/tumor/carcinoma/cancer
  • ovary/fallopian tube neoplasm/tumor/carcinoma/cancer (excl. teratoma/germinoma)
  • early death/lethality
  • weight loss/loss of appetite/break in weight curve/general health alteration

HPO human phenotypes related to Pseudomyxoma Peritonei:

(show all 17)
id Description Frequency HPO Source Accession
1 ascites hallmark (90%) HP:0001541
2 abnormality of the peritoneum hallmark (90%) HP:0002585
3 abnormality of the abdominal wall hallmark (90%) HP:0004298
4 inflammation of the large intestine typical (50%) HP:0002037
5 weight loss occasional (7.5%) HP:0001824
6 nausea and vomiting occasional (7.5%) HP:0002017
7 constipation occasional (7.5%) HP:0002019
8 abdominal pain occasional (7.5%) HP:0002027
9 respiratory insufficiency occasional (7.5%) HP:0002093
10 lymphadenopathy occasional (7.5%) HP:0002716
11 neoplasm of the pancreas occasional (7.5%) HP:0002894
12 intestinal obstruction occasional (7.5%) HP:0005214
13 neoplasm of the stomach occasional (7.5%) HP:0006753
14 abnormal renal physiology occasional (7.5%) HP:0012211
15 neoplasm of the colon occasional (7.5%) HP:0100273
16 ovarian neoplasm occasional (7.5%) HP:0100615
17 hernia occasional (7.5%) HP:0100790

Drugs & Therapeutics for Pseudomyxoma Peritonei

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Drug clinical trials:

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Search NIH Clinical Center for Pseudomyxoma Peritonei

Genetic Tests for Pseudomyxoma Peritonei

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Anatomical Context for Pseudomyxoma Peritonei

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MalaCards organs/tissues related to Pseudomyxoma Peritonei:

32
Appendix, Ovary, Colon, Testes, Small intestine, Pancreas, Lung, Spleen, Breast, Bone, Kidney, Liver, Skin

Animal Models for Pseudomyxoma Peritonei or affiliated genes

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MGI Mouse Phenotypes related to Pseudomyxoma Peritonei:

36 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.2CTNNB1, KRAS, TP53, APC
2MP:00020068.8APC, TP53, MUC2, KRAS, CDX2, CDH1
3MP:00053718.8APC, TP53, KRAS, CDX2, CTNNB1
4MP:00053798.7APC, TP53, MUC2, KRAS, CDX2, CDH1
5MP:00053698.7APC, TP53, VIM, KRAS, CDH2, CTNNB1
6MP:00107718.7CTNNB1, CDH1, KRAS, TP53, APC, F2
7MP:00028738.5F2, APC, TP53, KRAS, CDX2, CDH1
8MP:00053898.4F2, APC, TP53, VIM, KRAS, CDX2
9MP:00053818.2CTNNB1, F2, APC, TP53, MUC2, MUC5AC
10MP:00053808.2F2, APC, TP53, VIM, KRAS, CDX2
11MP:00053858.0F2, APC, TP53, VIM, MUC2, KRAS
12MP:00053877.9F2, APC, TP53, VIM, MUC2, MUC5AC
13MP:00053787.9F2, APC, TP53, VIM, MUC2, KRAS
14MP:00107687.8F2, APC, TP53, VIM, MUC2, KRAS
15MP:00053767.5F2, APC, TP53, VIM, MUC2, MUC5AC
16MP:00053847.5VIM, TP53, APC, F2, MUC2, KRAS

Publications for Pseudomyxoma Peritonei

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Articles related to Pseudomyxoma Peritonei:

(show top 50)    (show all 507)
idTitleAuthorsYear
1
Multicentre study of the learning curve and surgical performance of cytoreductive surgery with intraperitoneal chemotherapy for pseudomyxoma peritonei. (25329419)
2014
2
Appendiceal mucocele and pseudomyxoma peritonei; the clinical boundaries of a subtle disease. (25163976)
2014
3
Kras mutations and p53 overexpression in pseudomyxoma peritonei: association with phenotype and prognosis. (23199549)
2013
4
Aggressive pseudomyxoma peritonei: a case report with an unusual clinical presentation. (24324903)
2013
5
Role of preoperative sonography in the diagnosis and pathologic staging of pseudomyxoma peritonei. (23980216)
2013
6
Potential mucolytic agents for mucinous ascites from pseudomyxoma peritonei. (22359216)
2012
7
Pseudomyxoma peritonei (mucinous carcinoma peritonei) preceded by intraductal papillary neoplasm of the bile duct. (22406366)
2012
8
Mucolysis by ascorbic acid and hydrogen peroxide on compact mucin secreted in pseudomyxoma peritonei. (22261589)
2012
9
Evaluation of complete cytoreductive surgery and two intraperitoneal chemotherapy techniques in Pseudomyxoma peritonei. (22763244)
2012
10
Early- and long-term outcome data of patients with pseudomyxoma peritonei from appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. (22614976)
2012
11
Extraperitoneal presentation of pseudomyxoma peritonei as retroperitoneal invasion with skin fistula-a case report. (22202264)
2011
12
Commentary on 'Survival of patients with pseudomyxoma peritonei treated by serial debulking'. (20718839)
2010
13
Re: JSLS. 2009;13(2):203-206 Laparoscopic mucin removal in patients with pseudomyxoma peritonei. (20529543)
2010
14
Presumed fungal retinitis associated with pseudomyxoma peritonei. (21686849)
2009
15
Tailgut cyst, an unusual cause of pseudomyxoma peritonei. (19856666)
2009
16
Incidental finding of pseudomyxoma peritonei at primary cesarean section. (19399708)
2009
17
Chemo-hyperthermic peritoneal perfusion (CHPP) for appendiceal pseudomyxoma peritonei. (19390942)
2009
18
Adenocarcinoma of urachal cyst associated with pseudomyxoma peritonei masquerading as abdominal tuberculosis: A case report and review of literature. (19468408)
2008
19
Low-grade mucinous epithelial neoplasm (intestinal type) arising in a mature sacrococcygeal teratoma with late recurrence as pseudomyxoma peritonei. (18289636)
2008
20
Re: An evidence-based approach: Sugarbaker protocol and pseudomyxoma peritonei of appendiceal origin. (18959716)
2008
21
A phase II study evaluating the use of concurrent mitomycin C and capecitabine in patients with advanced unresectable pseudomyxoma peritonei. (18682713)
2008
22
Incidental finding of pseudomyxoma peritonei in a deceased organ donor: implications on organ donation. (17239029)
2007
23
Pseudomyxoma peritonei presenting with femoral hernias and peritonitis. (17508254)
2007
24
How safe and effective is surgery with intraperitoneal chemotherapy for pseudomyxoma peritonei? (17667901)
2007
25
Toxicity and mortality of cytoreduction and intraoperative hyperthermic intraperitoneal chemotherapy in pseudomyxoma peritonei--a report of 103 procedures. (16303281)
2006
26
Pseudomyxoma peritonei: A rose by any other name... (17063093)
2006
27
The etiology, clinical presentation, and management of pseudomyxoma peritonei. (14567019)
2003
28
Successful treatment of pseudomyxoma peritonei with intraperitoneal 10 per cent dextrose, sizofiran and cisplatin. (12521714)
2002
29
The subpyloric space: an important surgical and radiologic feature in pseudomyxoma peritonei. (12099657)
2002
30
Extensive surgical cytoreduction and intraoperative hyperthermic intraperitoneal chemotherapy in patients with pseudomyxoma peritonei (Br J Surg 2001; 88: 458-63). (11488802)
2001
31
Use of ultrasonic surgical aspirator in operative cytoreduction of pseudomyxoma peritonei. (10789759)
2000
32
Pseudomyxoma peritonei in the pleural cavity: report of a case. (10211530)
1999
33
Pseudomyxoma peritonei. (9660531)
1998
34
Pseudomyxoma peritonei: a report of eight cases. (7829144)
1994
35
Pseudomyxoma peritonei with progressive calcifications: CT findings. (1544550)
1992
36
Pseudomyxoma peritonei from metastatic colloid carcinoma of the breast. (1846836)
1991
37
Pseudomyxoma peritonei--experience from a tertiary referral centre. (1930042)
1991
38
Clinical and radiological features of pseudomyxoma peritonei. (2530349)
1989
39
Pseudomyxoma peritonei--preoperative diagnosis on CT scan. A report of 2 cases. (3150267)
1988
40
Pseudomyxoma peritonei--benign or malignant. (3758624)
1986
41
Computed tomography and magnetic resonance of pseudomyxoma peritonei. (4056150)
1985
42
Successful treatment of pseudomyxoma peritonei of ovarian origin with cis-platinum, doxorubicin, and cyclophosphamide. (4054721)
1985
43
Pseudomyxoma peritonei associated with mucinous adenocarcinoma of the pancreas: CT findings and CT-guided biopsy. (6323557)
1984
44
Pseudomyxoma peritonei of ovarian origin--an autopsy case. (161472)
1979
45
Pseudomyxoma peritonei. (4645609)
1972
46
Pseudomyxoma peritonei. New concepts in management with a report of seventeen patients. (5773930)
1969
47
Bluish translucent umbilical lesions of pseudomyxoma peritonei. (6046394)
1967
48
"MUCOCELE APPENDICIS" WITH PSEUDOMYXOMA PERITONEI AND PULMONARY METASTASES. (14154710)
1964
49
Pseudomyxoma peritonei due to mucocele of the appendix. A report of four cases and review of the literature. (13777126)
1961
50
Pseudomyxoma peritonei. (13655140)
1959

Variations for Pseudomyxoma Peritonei

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Expression for genes affiliated with Pseudomyxoma Peritonei

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Expression patterns in normal tissues for genes affiliated with Pseudomyxoma Peritonei

Search GEO for disease gene expression data for Pseudomyxoma Peritonei.

Pathways for genes affiliated with Pseudomyxoma Peritonei

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Pathways related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

(show all 39)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.9CTNNB1, CDX2
29.6TP53, CDX2, CDH1
39.6APC, CDX2, CTNNB1
49.6CTNNB1, CDH2, APC
59.6CTNNB1, CDH2, CDH1
69.6CDH1, CDH2, CTNNB1
7
Show member pathways
9.6CTNNB1, CDH2, CDH1
89.6APC, CDH1, CTNNB1
99.6APC, CDH1, CTNNB1
10
Show member pathways
RAC1 signaling pathway37
9.6CTNNB1, CDH1, APC
119.6CTNNB1, CDH1, APC
129.5CTNNB1, CDH2, VIM
13
Show member pathways
9.5TP53, KRAS, CTNNB1
149.5CTNNB1, KRAS, TP53
159.5APC, TP53, CTNNB1
16
Show member pathways
DNA damage response (only ATM dependent)37
Wnt Signaling Pathway and Pluripotency37
9.5CTNNB1, TP53, APC
179.5CTNNB1, CDH1, TP53
18
Show member pathways
9.4MUC5AC, MUC6, MUC5B, MUC2
19
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways60
Immune response IL 1 signaling pathway60
9.4MUC2, MUC5B, MUC5AC, KRAS
209.3KRAS, VIM, TP53, APC
219.3APC, CDH1, CDH2, CTNNB1
229.3CTNNB1, KRAS, TP53, APC
239.3APC, TP53, KRAS, CTNNB1
24
Show member pathways
9.3APC, TP53, KRAS, CTNNB1
259.2TP53, KRAS, CDH1, CTNNB1
269.2CTNNB1, CDH1, KRAS, TP53
27
Show member pathways
Signaling Pathways in Glioblastoma37
9.2CTNNB1, CDH1, KRAS, TP53
28
Show member pathways
9.2CTNNB1, CDH1, VIM, APC
29
Show member pathways
Wnt Signaling Pathway NetPath37
9.2CTNNB1, CDH1, TP53, APC
309.2APC, TP53, CDH1, CTNNB1
319.0CEACAM5, CDH1, CDH2, CTNNB1
329.0CTNNB1, CDH2, CDH1, APC, F2
33
Show member pathways
9.0APC, VIM, CDH1, CDH2, CTNNB1
34
Show member pathways
Signal transduction PTEN pathway60
9.0APC, TP53, KRAS, CDH1, CTNNB1
359.0CTNNB1, CDH1, KRAS, TP53, APC
36
Show member pathways
Proteasome Degradation37
Immune response Antigen presentation by MHC class I60
8.9APC, TP53, VIM, CDH1, CTNNB1
37
Show member pathways
8.6APC, TP53, VIM, CDH1, CDH2, CTNNB1
388.6CTNNB1, CDH2, CDH1, VIM, TP53, APC
39
Show member pathways
8.5F2, MUC2, MUC5B, MUC6, MUC5AC, CDX2

Compounds for genes affiliated with Pseudomyxoma Peritonei

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Compounds related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

(show top 50)    (show all 115)
idCompoundScoreTop Affiliating Genes
1exisulind449.8APC, CDH1, CTNNB1
2sodium bisulfite449.8CDH1, CTNNB1, APC
3aristolochic acid44 210.7TP53, CDH1, VIM
4o6-methylguanine449.7TP53, APC, CDH1, KRAS
5dicoumarol449.6TP53, F2, MUC5AC
6sulindac44 1110.5CTNNB1, APC, TP53, CDH1
75-methylcytosine44 2410.5APC, TP53, CDH1
8irinotecan44 50 1111.3TP53, CEACAM5, KRAS, CDH1
9cytosine44 2410.3CEACAM5, PSG2, CDH1, APC
10latex449.3CDH1, PSG2, CDH2, CEACAM5
11nocodazole44 1110.3VIM, CTNNB1, CDH1, TP53, APC
12p002449.2CDH1, CTNNB1, KRAS, PSG2, CEACAM5
13vitamin d449.1APC, CDH1, CTNNB1, CDX2, KRAS, VIM
14matrigel449.1CTNNB1, VIM, KRT7, CDH1, CDH2
15tamoxifen44 50 28 1112.0F2, TP53, VIM, CDH1, CTNNB1
16rapamycin449.0KRAS, VIM, APC, CTNNB1, CDH1
17n acetylcysteine449.0CDH1, MUC5AC, CTNNB1, F2, TP53
18carbohydrates448.9CDH1, CEACAM5, MUC5AC, MUC2, KRT7
19sb 20358044 619.9TP53, MUC5AC, VIM, MUC2, CDH1, CTNNB1
20methotrexate50 44 1110.9MUC2, VIM, KRT7, CDH1, MUC5AC, F2
21adriamycin448.8TP53, VIM, CDH1, CTNNB1, PSG2, CEACAM5
22crcs448.7CTNNB1, CDH1, APC, TP53, MUC2, CEACAM5
23formaldehyde44 249.7CDH1, VIM, KRT20, KRT7, PSG2
24retinoid448.7CDH1, MUC5AC, VIM, TP53, KRT7, CTNNB1
25paclitaxel44 50 1110.6CTNNB1, CDH1, KRAS, TP53, VIM
26polysaccharide448.6CTNNB1, CEACAM5, KRT7, MUC6, CDH2, MUC5AC
27sialic acid448.6PSG2, KRT7, CDH1, CEACAM5, MUC2, CDH2
28hyaluronic acid44 249.5CDH1, KRT20, CEACAM5, VIM, F2
29gefitinib44 50 1110.5KRAS, CDH1, CEACAM7, CTNNB1, CEACAM5, VIM
30thymidine44 249.5CEACAM7, PSG2, TP53, CEACAM5, CTNNB1, CDX2
31phosphatidylinositol448.4MUC5AC, APC, CEACAM5, KRAS, CDH1, CTNNB1
32cysteine448.3CTNNB1, MUC5AC, MUC2, CEACAM5, CDX2, CDH1
335-aza-2deoxycytidine448.2KRT7, CDX2, CDH1, CDH2, CTNNB1, MUC2
34glycogen44 249.2PSG2, CDH1, CDH2, KRT7, CEACAM5, VIM
35glucose448.2MUC2, CDH2, KRT7, PSG2, CEACAM5, MUC5AC
36mucicarmine448.2KRT20, KRT7, CEACAM7, CEACAM5, VIM
37oligonucleotide448.1CDH2, VIM, MUC2, MUC5AC, TP53, APC
38doxorubicin44 50 1110.0TP53, CEACAM5, KRT20, PSG2, VIM, CTNNB1
39serine447.9CTNNB1, CDH1, KRAS, CDH2, MUC2, MUC5AC
40butyrate447.8TP53, CDH1, VIM, CDX2, CEACAM7, KRAS
41hematoxylin447.7VIM, MUC2, MUC5AC, CEACAM5, PSG2, KRT7
42testosterone44 61 24 1110.7KRT7, APC, VIM, MUC5AC, CTNNB1, CDH2
435fluorouracil447.5TP53, MUC2, MUC5AC, CEACAM5, CEACAM7, PSG2
44b 723447.4CDH2, CDH1, KRT20, VIM, CEACAM5, KRT7
45retinoic acid44 248.1MUC2, CEACAM7, VIM, KRAS, KRT7, CDH1
46vegf447.1KRT20, TP53, CTNNB1, CEACAM5, PSG2, KRAS
47tyrosine447.0CTNNB1, APC, KRT20, CDH2, MUC5AC, CEACAM5
48paraffin445.8KRT7, KRAS, PSG2, CEACAM5, MUC5AC, MUC6
49progesterone44 28 61 24 119.6CTNNB1, CDH2, CDH1, CDX2, KRT20, KRT7
50estrogen445.1KRAS, CTNNB1, CDH1, CDX2, KRT20, KRT7

GO Terms for genes affiliated with Pseudomyxoma Peritonei

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Cellular components related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1beta-catenin destruction complexGO:0308779.9CTNNB1, APC
2fascia adherensGO:0059169.9CTNNB1, CDH2
3catenin complexGO:0163429.7CDH1, CDH2, CTNNB1
4lateral plasma membraneGO:0163289.7CTNNB1, CDH1, APC
5cell-cell adherens junctionGO:0059139.5APC, CDH1, CDH2, CTNNB1
6lamellipodiumGO:0300279.5CTNNB1, CDH2, APC
7Golgi lumenGO:0057969.3MUC5AC, MUC6, MUC5B, MUC2, F2
8basolateral plasma membraneGO:0163239.3CTNNB1, CDH1, CEACAM5
9intermediate filamentGO:0058828.9VIM, KRT7, KRT20
10extracellular regionGO:0055768.4F2, MUC5B, MUC6, REG4, PSG2, CDH1

Biological processes related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1maintenance of gastrointestinal epitheliumGO:03027710.1MUC2, MUC6
2regulation of protein localization to cell surfaceGO:200000810.1CDH1, CTNNB1
3cellular response to indole-3-methanolGO:07168110.0CDH1, CTNNB1
4canonical Wnt signaling pathway involved in negative regulation of apoptotic processGO:04433610.0APC, CTNNB1
5striated muscle cell differentiationGO:05114610.0CDH2, KRAS
6proximal/distal pattern formationGO:0099549.8CTNNB1, APC
7negative regulation of canonical Wnt signaling pathwayGO:0900909.8CDH2, CDH1, APC
8T cell differentiation in thymusGO:0330779.7CTNNB1, TP53, APC
9O-glycan processingGO:0162669.7MUC2, MUC5B, MUC6, MUC5AC
10trophectodermal cell differentiationGO:0018299.7CDH1, CDX2
11cell migrationGO:0164779.6APC, PSG2, CDH2
12cellular component disassembly involved in execution phase of apoptosisGO:0069219.5CTNNB1, CDH1, VIM, APC
13intermediate filament organizationGO:0451099.4VIM, KRT20
14post-translational protein modificationGO:0436879.4F2, MUC2, MUC5B, MUC6, MUC5AC
15cellular protein metabolic processGO:0442679.3F2, MUC2, MUC5B, MUC6, MUC5AC
16apoptotic processGO:0069158.3APC, TP53, VIM, KRT20, CDH1, CTNNB1

Molecular functions related to Pseudomyxoma Peritonei according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1alpha-catenin bindingGO:0452949.8CTNNB1, CDH2
2gamma-catenin bindingGO:0452959.7APC, CDH1, CDH2
3beta-catenin bindingGO:0080139.4CDH2, CDH1, APC
4protein phosphatase bindingGO:0199039.3CTNNB1, CDH2, CDH1, TP53
5protein bindingGO:0055156.3F2, APC, TP53, VIM, MUC2, MUC5B

Products for genes affiliated with Pseudomyxoma Peritonei

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  • Antibodies
  • Proteins
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Sources for Pseudomyxoma Peritonei

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet