MCID: PSR004
MIFTS: 15

Psoriasis Susceptibility 1 malady

Summaries for Psoriasis Susceptibility 1

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47OMIM, 33MalaCards
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MalaCards: Psoriasis Susceptibility 1 is related to psoriatic arthritis and hiv-1 viremia. An important gene associated with Psoriasis Susceptibility 1 is PSORS1 (psoriasis susceptibility 1). The compound allopurinol have been mentioned in the context of this disorder. Affiliated tissues include skin.

Description from OMIM:47 177900

Aliases & Classifications for Psoriasis Susceptibility 1

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47OMIM, 61UMLS
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Aliases & Descriptions:

psoriasis susceptibility 1 47 61


Related Diseases for Psoriasis Susceptibility 1

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17GeneCards, 18GeneDecks
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Clinical Features for Psoriasis Susceptibility 1

Sources:
47OMIM
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Clinical features from OMIM:

177900

Clinical synopsis from OMIM:

177900

Drugs & Therapeutics for Psoriasis Susceptibility 1

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Psoriasis Susceptibility 1

Drug clinical trials:

Search ClinicalTrials for Psoriasis Susceptibility 1

Search NIH Clinical Center for Psoriasis Susceptibility 1

Search CenterWatch for Psoriasis Susceptibility 1

Genetic Tests for Psoriasis Susceptibility 1

Anatomical Context for Psoriasis Susceptibility 1

Sources:
33MalaCards
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MalaCards organs/tissues related to Psoriasis Susceptibility 1:

33
Skin

Animal Models for Psoriasis Susceptibility 1 or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Psoriasis Susceptibility 1

Sources:
51PubMed
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Articles related to Psoriasis Susceptibility 1:

idTitleAuthorsYear
1
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. (19169255)
2009
2
Co-localization of susceptibility loci for psoriasis (PSORS4) and atopic dermatitis (ATOD2) on human chromosome 1q21. (16912508)
2006
3
Vitamin D receptor gene polymorphisms, particularly the novel A-1012G promoter polymorphism, are associated with vitamin D3 responsiveness and non-familial susceptibility in psoriasis. (15864137)
2005
4
Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25, linked to psoriasis susceptibility. (12483297)
2003
5
Fine mapping of the PSORS4 psoriasis susceptibility region on chromosome 1q21. (11348461)
2001
6
Genomewide scan in german families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13. (10986047)
2000
7
Association analysis using refined microsatellite markers localizes a susceptibility locus for psoriasis vulgaris within a 111kb segment telomeric to the HLA-C gene. (10545595)
1999
8
A susceptibility locus for epidermodysplasia verruciformis, an abnormal predisposition to infection with the oncogenic human papillomavirus type 5, maps to chromosome 17qter in a region containing a psoriasis locus. (10084299)
1999
9
HLA-DRB1*0701 and DRB1*1401 are associated with genetic susceptibility to psoriasis vulgaris in a Taiwanese population. (9990359)
1998

Genetic Variations for Psoriasis Susceptibility 1

Expression for genes affiliated with Psoriasis Susceptibility 1

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Psoriasis Susceptibility 1

Search GEO for disease gene expression data for Psoriasis Susceptibility 1.

Pathways for genes affiliated with Psoriasis Susceptibility 1

Compounds for genes affiliated with Psoriasis Susceptibility 1

Sources:
45Novoseek, 50PharmGKB, 11DrugBank
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Compounds related to Psoriasis Susceptibility 1 according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1allopurinol45 50 1111.7PSORS1C2, PSORS1C3, PSORS1C1

GO Terms for genes affiliated with Psoriasis Susceptibility 1

Products for genes affiliated with Psoriasis Susceptibility 1

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Psoriasis Susceptibility 1

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet