MCID: PSR004
MIFTS: 17

Psoriasis Susceptibility 1 malady

Genetic diseases (common) category
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Summaries for Psoriasis Susceptibility 1

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MalaCards based summary: Psoriasis Susceptibility 1 is related to psoriasis and skin disease, and has symptoms including An important gene associated with Psoriasis Susceptibility 1 is HLA-C (major histocompatibility complex, class I, C). Affiliated tissues include skin.

Description from OMIM:46 177900

Aliases & Classifications for Psoriasis Susceptibility 1

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Psoriasis Susceptibility 1, Aliases & Descriptions:

Name: Psoriasis Susceptibility 1 46 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Related Diseases for Psoriasis Susceptibility 1

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Symptoms for Psoriasis Susceptibility 1

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Symptoms by clinical synopsis from OMIM:

177900

Clinical features from OMIM:

177900

HPO human phenotypes related to Psoriasis Susceptibility 1:

id Description Frequency HPO Source Accession
1 arthritis HP:0001369
2 multifactorial inheritance HP:0001426
3 nail pits HP:0001803
4 onycholysis HP:0001806
5 psoriasis HP:0003765

Drugs & Therapeutics for Psoriasis Susceptibility 1

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Drug clinical trials:

Search ClinicalTrials for Psoriasis Susceptibility 1

Search NIH Clinical Center for Psoriasis Susceptibility 1

Genetic Tests for Psoriasis Susceptibility 1

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Anatomical Context for Psoriasis Susceptibility 1

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MalaCards organs/tissues related to Psoriasis Susceptibility 1:

32
Skin

Animal Models for Psoriasis Susceptibility 1 or affiliated genes

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Publications for Psoriasis Susceptibility 1

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Articles related to Psoriasis Susceptibility 1:

idTitleAuthorsYear
1
Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene. (16642438)
2006

Variations for Psoriasis Susceptibility 1

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Clinvar genetic disease variations for Psoriasis Susceptibility 1:

6
id Gene Name Type Significance SNP ID Assembly Location
1HLA-CHLA-C, HLA-Cw6undetermined variantrisk factor

Expression for genes affiliated with Psoriasis Susceptibility 1

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Expression patterns in normal tissues for genes affiliated with Psoriasis Susceptibility 1

Search GEO for disease gene expression data for Psoriasis Susceptibility 1.

Pathways for genes affiliated with Psoriasis Susceptibility 1

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Compounds for genes affiliated with Psoriasis Susceptibility 1

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GO Terms for genes affiliated with Psoriasis Susceptibility 1

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Cellular components related to Psoriasis Susceptibility 1 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.7CDSN, PSORS1C2, HLA-C

Products for genes affiliated with Psoriasis Susceptibility 1

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  • Antibodies
  • Proteins
  • Lysates

Sources for Psoriasis Susceptibility 1

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet