MCID: PSR004
MIFTS: 19

Psoriasis Susceptibility 1 malady

Genetic diseases (common) category

Aliases & Classifications for Psoriasis Susceptibility 1

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Aliases & Descriptions for Psoriasis Susceptibility 1:

Name: Psoriasis Susceptibility 1 46 9 61
 
Psoriasis 1 46


Classifications:



External Ids:

OMIM46 177900

Summaries for Psoriasis Susceptibility 1

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OMIM:46 Psoriasis (psoriasis vulgaris; PV) is a chronic inflammatory dermatosis that affects approximately 2% of the... (177900) more...

MalaCards based summary: Psoriasis Susceptibility 1, also known as psoriasis 1, is related to psoriasis and herpes simplex, and has symptoms including arthritis, multifactorial inheritance and nail pits. An important gene associated with Psoriasis Susceptibility 1 is HLA-C (major histocompatibility complex, class I, C). Affiliated tissues include skin.

Related Diseases for Psoriasis Susceptibility 1

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Diseases in the Psoriasis Susceptibility 1 family:

Psoriasis Susceptibility 13 Psoriasis Susceptibility 2

Diseases related to Psoriasis Susceptibility 1 via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1psoriasis29.7CDSN, PSORS1C2, HLA-C
2herpes simplex10.1
3skin disease9.9CDSN, HLA-C
4hypersensitivity syndrome, carbamazepine-induced9.7PSORS1C1, HLA-C

Symptoms for Psoriasis Susceptibility 1

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Symptoms by clinical synopsis from OMIM:

177900

Clinical features from OMIM:

177900

HPO human phenotypes related to Psoriasis Susceptibility 1:

id Description Frequency HPO Source Accession
1 arthritis HP:0001369
2 multifactorial inheritance HP:0001426
3 nail pits HP:0001803
4 onycholysis HP:0001806
5 psoriasis HP:0003765

Drugs & Therapeutics for Psoriasis Susceptibility 1

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Drug clinical trials:

Search ClinicalTrials for Psoriasis Susceptibility 1

Search NIH Clinical Center for Psoriasis Susceptibility 1

Genetic Tests for Psoriasis Susceptibility 1

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Anatomical Context for Psoriasis Susceptibility 1

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MalaCards organs/tissues related to Psoriasis Susceptibility 1:

31
Skin

Animal Models for Psoriasis Susceptibility 1 or affiliated genes

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Publications for Psoriasis Susceptibility 1

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Articles related to Psoriasis Susceptibility 1:

idTitleAuthorsYear
1
Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene. (16642438)
2006

Variations for Psoriasis Susceptibility 1

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Clinvar genetic disease variations for Psoriasis Susceptibility 1:

5
id Gene Variation Type Significance SNP ID Assembly Location
1HLA-CHLA-C, HLA-Cw6undetermined variantrisk factor

Expression for genes affiliated with Psoriasis Susceptibility 1

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Search GEO for disease gene expression data for Psoriasis Susceptibility 1.

Pathways for genes affiliated with Psoriasis Susceptibility 1

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Compounds for genes affiliated with Psoriasis Susceptibility 1

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GO Terms for genes affiliated with Psoriasis Susceptibility 1

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Cellular components related to Psoriasis Susceptibility 1 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.7CDSN, PSORS1C2, HLA-C

Sources for Psoriasis Susceptibility 1

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet