MCID: PSR001
MIFTS: 64

Psoriatic Arthritis malady

Categories: Genetic diseases (common), Skin diseases

Aliases & Classifications for Psoriatic Arthritis

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Aliases & Descriptions for Psoriatic Arthritis:

Name: Psoriatic Arthritis 52 11 25 70 27 38 13
Psoriatic Arthropathy 11 25 70
Arthropathic Psoriasis 11 25
Arthritis, Psoriatic 39 68
Psoriatic Arthritis, Susceptibility to 12
 
Psoriasis Arthropathica 70
Arthritis Psoriatica 11
Arthritic Psoriasis 70
Arthritis Psoriatic 50
Psoras 70

Classifications:



External Ids:

OMIM52 607507
Disease Ontology11 DOID:9008
ICD1030 L40.5, L40.50
ICD9CM32 696.0
MeSH39 D015535
NCIt45 C61277

Summaries for Psoriatic Arthritis

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MedlinePlus:38 Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales. you usually get them on your elbows, knees, scalp, back, face, palms and feet, but they can show up on other parts of your body. some people with psoriasis have psoriatic arthritis. it causes pain, stiffness, and swelling of the joints. it is often mild, but can sometimes be serious and affect many joints. the joint and skin problems don't always happen at the same time. your doctor will do a physical exam and imaging tests to diagnose psoriatic arthritis. there is no cure, but medicines can help control inflammation and pain. in rare cases, you might need surgery to repair or replace damaged joints.

MalaCards based summary: Psoriatic Arthritis, also known as psoriatic arthropathy, is related to skin disease and systemic lupus erythematosus, and has symptoms including pathergy reaction, joint related signs and symptoms and sciatica. An important gene associated with Psoriatic Arthritis is LTA (Lymphotoxin Alpha), and among its related pathways are Canonical NF-kappaB pathway and Osteoblast Signaling. The drugs etanercept and auranofin have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and bone, and related mouse phenotypes are Increased shRNA abundance (Z-score > 2) and Synthetic lethal with MLN4924 (a NAE inhibitor).

UniProtKB/Swiss-Prot:70 Psoriatic arthritis: An inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoid like pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis).

Genetics Home Reference:25 Psoriatic arthritis is a condition involving joint inflammation (arthritis) that usually occurs in combination with a skin disorder called psoriasis. Psoriasis is a chronic inflammatory condition characterized by patches of red, irritated skin that are often covered by flaky white scales. People with psoriasis may also have changes in their fingernails and toenails, such as nails that become pitted or ridged, crumble, or separate from the nail beds.

OMIM:52 Psoriasis (177900) is a chronic inflammatory skin disease that may have an autoimmune basis. The disorder has a strong... (607507) more...

Disease Ontology:11 A syndrome that occurs in humans with psoriasis who also experience symptoms similar to arthritis.

Wikipedia:71 Psoriatic arthritis (also arthritis psoriatica, arthropathic psoriasis or psoriatic arthropathy) is a... more...

Related Diseases for Psoriatic Arthritis

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Diseases related to Psoriatic Arthritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 286)
idRelated DiseaseScoreTop Affiliating Genes
1skin disease30.5IL13, IL1B, TNF
2systemic lupus erythematosus29.7CRP, LTA, PTPN22, TNF, TNFRSF1B, TNIP1
3myelitis29.5IL1B, TNF, TNFRSF1A
4atherosclerosis29.4IL1B, LTA, MICA, MMP3, PTPN22, TNF
5rheumatoid arthritis27.7COMP, CRP, HLA-B, IL1B, MMP3, PTPN22
6spondyloarthropathy 111.7
7arthritis11.6
8psoriasis11.6
9psoriatic juvenile idiopathic arthritis11.3
10thyroid malformation10.8IL1B, TNF
11panuveitis10.7HLA-C, LTA, TNF
12keratomalacia10.7HLA-B, HLA-C, TNF
13lipodermatosclerosis10.7HLA-B, HLA-C, TNF
14arachnoiditis10.7HLA-B, HLA-C, TNF
15hypospadias, hypertelorism, upper lid coloboma, and mixed-type hearing loss10.7IL1B, TNF
16hemophagocytic lymphohistiocytosis10.7HLA-B, HLA-C, TNF
17epstein-barr virus hepatitis10.7CRP, HLA-B, TNF
18gonococcal iridocyclitis10.7HLA-B, HLA-C
19panner disease10.7CRP, TNF
20cartilage disease10.7CRP, IL1B, TNF
21gastric dilatation10.7HLA-B, IL1B, TNF
22haemophilus influenzae10.6HLA-C, NOD2
23common cold10.6IL1B, LTA, TNF
24bacteriuria10.6IL1B, LTA, TNF
25corneal intraepithelial neoplasm10.6HLA-B, IL1B, TNF
26paraneoplastic polyneuropathy10.6CRP, IL1B, TNF
27oral candidiasis10.6CRP, IL1B, TNF
28antigen-peptide-transporter 2 deficiency10.6HLA-B, PTPN22, TNF
29allergic hypersensitivity disease10.6HLA-B, TNF, TNFRSF1B
30cervix erosion10.6CRP, IL1B, TNF
31meier-gorlin syndrome 310.6IL1B, NOD2, TNF
32intestinal variant cervical mucinous adenocarcinoma10.6CRP, IL1B, TNF
33neonatal period electroclinical syndrome10.6CRP, IL1B, TNF
34ascending cholangitis10.6HLA-B, HLA-C, MICA, TNF
35spondylolysis10.6CRP, IL1B, TNF
36steroid-induced glaucoma10.6CRP, MMP3, TNF
37diphtheria10.6CRP, IL1B, TNF
38mononeuritis of lower limb10.6CRP, IL1B, TNF
39early congenital syphilis10.6CRP, TNF, TNFRSF1B
40baetz-greenwalt syndrome10.6IL1B, TNF
41lipid storage disease10.6CRP, HLA-B, TNF
42lymphopenia10.6CRP, IL1B, TNF
43chromosome 9p deletion syndrome10.6NOD2, TNF, TNFRSF1B
44night blindness10.6MMP3, TNF, TNFRSF1B
45lacrimal system cancer10.6NOD2, TNF, TNFRSF1B
46opportunistic bacterial infectious disease10.6CRP, IL1B, TNF
47common variable immunodeficiency10.6HLA-B, TNF
48spinal canal and spinal cord meningioma10.6CRP, IL1B, TNF
49mandibular cancer10.6CRP, IL1B, TNF
50conjunctival pigmentation10.6HLA-B, HLA-C, PTPN22

Graphical network of the top 20 diseases related to Psoriatic Arthritis:



Diseases related to psoriatic arthritis

Symptoms & Phenotypes for Psoriatic Arthritis

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Clinical features from OMIM:

607507

UMLS symptoms related to Psoriatic Arthritis:


pathergy reaction, joint related signs and symptoms, sciatica, muscle cramp, exanthema, back pain

GenomeRNAi Phenotypes related to Psoriatic Arthritis according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-359.5HLA-B, HLA-C, MICA, NOD2, SELE
2GR00250-A-18.1IL1B, LTA, NOD2, TNF, TNFRSF11B, TNFRSF1A

MGI Mouse Phenotypes related to Psoriatic Arthritis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.5LTA, PTPN22, SELE, TNF, TNFRSF1A, TNFRSF1B
2MP:00053819.2IL13, NOD2, PTPN22, TNF, TNFRSF1A, TNFRSF1B
3MP:00053889.1IL13, LTA, PTPN22, SELE, TNF, TNFRSF1A
4MP:00107719.0IL13, IL1B, SELE, TNF, TNFRSF1A, TNFRSF1B
5MP:00053908.4COMP, IL13, IL1B, LTA, MMP3, NOD2
6MP:00053858.3COMP, CRP, IL1B, LTA, PTPN22, SELE
7MP:00053788.1COMP, IL13, LTA, NOD2, PTPN22, SELE
8MP:00053977.9IL13, IL1B, LTA, MMP3, NOD2, PTPN22
9MP:00053767.6COMP, CRP, IL13, IL1B, LTA, MMP3
10MP:00053877.5COMP, CRP, IL13, IL1B, LTA, MMP3

Drugs & Therapeutics for Psoriatic Arthritis

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Drugs for Psoriatic Arthritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 164)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Etanerceptapproved, investigationalPhase 4, Phase 3, Phase 2397185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
2
AdalimumabapprovedPhase 4, Phase 3, Phase 2478331731-18-116219006
Synonyms:
331731-18-1
Adalimumab
Adalimumab (USAN/INN)
Adalimumab (genetical recombination)
 
Adalimumab (genetical recombination) (JAN)
D02597
Humira
Humira (TN)
Humira Pen
Ig gamma-1 chain C region
3
Certolizumab pegolapprovedPhase 4, Phase 3, Phase 1122428863-50-7
Synonyms:
428863-50-7
CDP870
Certolizumab pegol
 
Certolizumab pegol (USAN/INN)
Certolizumab pegol (genetical recombination)
Certolizumab pegol (genetical recombination) (JAN)
D03441
cimzia
4
ZincapprovedPhase 422317440-66-632051, 23994
Synonyms:
30Zn
Cinc
Zinc
Zinc ion
 
Zincum
Zink
Zn
Zn(ii)
Zn2+
5
Dimethyl fumarateapproved, investigationalPhase 4, Phase 3, Phase 281624-49-75271565, 637568
Synonyms:
(E)-CH3OC(O)CH=CHC(O)OCH3
(e)-But-2-enedioic acid dimethyl ester
1,2-Bis(methoxycarbonyl)-trans-Ethylene
1,2-Bis(methoxycarbonyl)-trans-ethylene
2-Butenedioic acid (2E)-, 1,4-dimethyl ester
2-Butenedioic acid (2E)-, dimethyl ester
2-Butenedioic acid (E)-, dimethyl ester
2-Butenedioic acid, dimethyl ester
Allomaleic acid dimethyl ester
BG 12 compound
BG-12
Boletic acid dimethyl ester
But-2-enedioic acid, dimethyl ester
Dimethyl (2E)-2-butenedioate
Dimethyl (2E)-but-2-enedioate
Dimethyl (E)-but-2-enedioate
Dimethyl but-2-enedioate
Dimethyl ester(2E)-2-Butenedioic acid
 
Dimethyl ester(E)-2-Butenedioic acid
Dimethyl fumarate
Dimethyl fumarate (usan)
Dimethyl trans-ethylenedicarboxylate
Dimethylester kyseliny fumarove
Dimethylfumarate
Fumaderm
Fumaric acid dimethyl ester
Fumaric acid, dimethyl ester
Fumaric acid, dimethyl ester (8CI)
Maleic acid, dimethyl ester
Methyl fumarate
Tecfidera
Trans-butenedioic acid dimethyl ester
dimethyl (E) butenedioate
trans-1, 2-Ethylenedicarboxylic acid dimethyl ester
trans-1,2-Ethylenedicarboxylic Acid dimethyl ester
trans-1,2-Ethylenedicarboxylic acid dimethyl ester
trans-Butenedioic acid dimethyl ester
6
InfliximabapprovedPhase 4, Phase 3, Phase 2378170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
7
Apremilastapproved, investigationalPhase 4, Phase 3, Phase 2, Phase 164608141-41-911561674
Synonyms:
Apremilast
Apremilast (USAN)
Apremilastum
Aprémilast
CC-10004
 
CHEBI:558773
CHEMBL514800
CID11561674
D08860
N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide
N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide
8
MentholapprovedPhase 4, Phase 323532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
9
MethotrexateapprovedPhase 4, Phase 3, Phase 2, Phase 115181959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
10
BenzocaineapprovedPhase 4, Phase 3, Phase 218921994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
11
Ustekinumabapproved, investigationalPhase 4, Phase 3, Phase 282815610-63-0
Synonyms:
 
Stelera
12
Cyclosporineapproved, investigational, vet_approvedPhase 4, Phase 1, Phase 291579217-60-0, 59865-13-35284373, 6435893
Synonyms:
1c5f
1cyn
30024_FLUKA
30024_SIGMA
59865-13-3
79217-60-0
AC1L1EQW
AC1NQXJE
AC1NR4C4
AC1NUQK3
AC1NUZNC
AC1O5KOG
AC1Q2UDG
Ambap59865-13-3
Ambotz59865-13-3
Antibiotic S 7481F1
BMT-ABA-SAR-MLE-VAL-MLE-ALA-ALA-MLE-MLE-MVA
BMT-ABA-SAR-MLE-VAL-MLE-ALA-DAL-MLE-MLE-MVA
BPBio1_000496
BRD-A64290322-001-01-6
BRD-A69815203-001-04-3
BRD-K13533483-001-03-0
BSPBio_000450
BSPBio_001596
BSPBio_003186
C 3662
C05086
C1832_SIGMA
C3662_SIGMA
C62H111N11O12
CB-01-09 MMX
CHEBI:106343
CHEBI:328305
CHEBI:4031
CHEMBL160
CHEMBL386389
CHEMBL532318
CID2909
CID5280754
CID5284373
CID5458585
CID5497195
CID6435893
CSA
CYCLOSPORIN A (SEE ALSO TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A))
CYCLOSPORIN A, USP
Ciclosporin
Ciclosporin (JP15)
Ciclosporina
Ciclosporine
Ciclosporinum
Cipol N
Cipol-N
Consupren
Consupren S
CsA
CsA & IFN.alpha.
CyA
Cyclokat
Cyclosporin
Cyclosporin A
Cyclosporin A & IFN.alpha.
Cyclosporin A Implant
Cyclosporin A, Tolypocladium inflatum
Cyclosporine (USP)
Cyclosporine A
Cyclosporine [USAN]
D00184
DE-076
DivK1c_000871
EU-0100242
Equoral
GNF-Pf-2808
Gengraf
Gengraf (TN)
HMS1569G12
HMS1791P18
HMS1921L20
HMS1989P18
HMS2089A09
HMS2092F06
HMS502L13
Helv Chim Acta 60: 1568 (1977)
 
I06-0379
I06-0966
IDI1_000871
KBio1_000871
KBio2_000780
KBio2_003348
KBio2_005916
KBio3_002686
KBioGR_001898
KBioSS_000780
LMPK14000003
LS-257
LS-58836
Lopac0_000242
MLS000028376
MLS001333756
MLS002153454
MLS002207033
Mitogard
Modusik-A
MolPort-000-760-988
MolPort-005-934-008
MolPort-006-705-994
NCGC00093704-01
NCGC00093704-02
NCGC00093704-03
NCGC00093704-04
NCGC00093704-05
NCGC00093704-06
NCGC00093704-07
NCGC00093704-08
NCGC00164258-01
NCGC00164258-02
NINDS_000871
NSC290193
Neoplanta
Neoral
Neoral (TN)
NeuroSTAT
Nova-22007
OL 27-400
OL-27400
OLO-400
Papilock
Prestwick2_000435
Prestwick3_000435
Prestwick_731
Pulminiq
Ramihyphin A
Restasis
Restasis (TN)
S-Neoral
S1514_Selleck
SDZ-OXL 400
SMR000058578
SPBio_001467
SPECTRUM1502202
ST-603
Sandimmun
Sandimmun Neoral
Sandimmune
Sandimmune (TN)
Sandimmune, Gengraf, Restasis, Atopica, Sangcya, Cyclosporine
Sang-2000
Sang-35
SangCyA
Sangcya
Sigmasporin
Sigmasporin Microoral
Spectrum2_001484
Spectrum3_001593
Spectrum4_001279
Spectrum5_001628
Spectrum_000300
TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A)
Vekacia
Zyclorin
cyclophorine
cyclosporin A
cyclosporine
from Tolypocladium inflatum (Trichoderma polysporin)
nchembio.184-comp6
nchembio.301-comp5
nchembio.342-comp1
13
Triamcinoloneapproved, vet_approvedPhase 4482124-94-731307
Synonyms:
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione
11.Beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11.beta.,16.alpha.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
124-94-7
4-08-00-03629 (Beilstein Handbook Reference)
83474-03-7
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-16-alpha-hydroxyprednisolone
9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahy
9.Alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-d
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-Fluoro-16alpha-hydroxyprednisolone
9α-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-16α-hydroxyprednisolone
AC-2072
AC1L1LDH
AC1Q5HJC
Adcortyl
Aristocort
Aristocort A
Aristocort Tablets
Aristogel
Aristospan
Azmacort
BPBio1_000154
BRD-K77554836-001-03-3
BRN 2341955
BSPBio_000140
Bio-0662
C21H27FO6
CHEMBL1451
CID31307
CL 19823
Celeste
Cinolone
Cinolone-T
D00385
D014221
DB00620
Delphicort
EINECS 204-718-7
EU-0101179
Fluoxiprednisolone
Fluoxyprednisolone
Flutex
Fougera
HMS1568G22
HMS2090D12
HSDB 3194
Kenacort
Kenacort (TN)
Kenacort-A
Kenacort-AG
Kenacort-Ag
Kenalog
Kenalog in Orabase
Kenalog-10
Kenalog-40
Kenalog-H
LS-698
Ledercort
Lopac0_001179
 
MLS000028542
MLS001066543
MLS002695935
MolPort-002-528-981
Mycolog
NCGC00021580-03
NCGC00021580-04
NCGC00021580-05
NCGC00021580-06
NCGC00021580-07
NCI60_000750
NSC 13397
NSC13397
Nasacort
Nasacort Aq
Nasacort Hfa
Omcilon
Omicilon
Oracort
Oralone
Orion
Polcortolon
Pregna-1,4-diene-3,20-dio
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy- (8CI)
Prestwick0_000120
Prestwick1_000120
Prestwick2_000120
Prestwick3_000120
Prestwick_438
Rodinolone
S1933_Selleck
SK-Triamcinolone
SMP1_000300
SMR000058333
SPBio_002079
Sk-Triamcinolone
T6376_SIGMA
TRIAMCINOLONE (SEE ALSO TRIAMCINOLONE ACETONIDE (76-25-5) AND TRIAMCINOLONE DIACETATE (67-78-7))
Tiamcinolonum
Tiamcinolonum [INN-Latin]
Tri-Nasal
Triacet
Triacort
Triam-Tablinen
Triamcet
Triamcinalone
Triamcinlon
Triamcinolon
Triamcinolona
Triamcinolona [INN-Spanish]
Triamcinolone (JP15/USP/INN)
Triamcinolone [USAN:INN:BAN:JAN]
Triamcinolone acetonide
Triamcinolone diacetate
Triamcinolone hexacetonide
Triamcinolonum
Triamcinolonum [INN]
Triatex
Tricortale
Triderm
Trilone
Tristoject
Trymex
UNII-1ZK20VI6TY
Vetalog
Volon
Volon A
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ GQ
ZINC03882036
droxypregna-1,4-diene-3,20-dione
ione
nchembio.2007.53-comp7
triamcinolone
14
AcitretinapprovedPhase 43055079-83-96437841, 5284513
Synonyms:
(2E,4E,6E,8E)-3,7-dimethyl-9-[2,3,6-trimethyl-4-(methyloxy)phenyl]nona-2,4,6,8-tetraenoic acid
(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
(all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
(all-e)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
13-cis-Acitretin
44707_FLUKA
44707_SIGMA
54757-46-9
55079-83-9
9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
AC-4702
AC1NR4LJ
AC1Q5T6I
Acetretin
Acitretin
Acitretin (USAN/INN)
Acitretin [USAN:INN:BAN]
Acitretina
Acitretina [Spanish]
Acitretine
Acitretine [French]
Acitretinum
Acitretinum [Latin]
BIDD:GT0617
Bio-0002
CCRIS 5534
CHEBI:50173
CHEMBL1131
CID5284513
CPD000499573
 
D02754
EINECS 259-474-4
Etretin
FT-0082892
HSDB 7187
Isoacitretin
Isoetretin
LS-96920
MLS001076667
MolPort-003-925-892
NCGC00163127-01
NCGC00163127-02
Neotigason
Retinoid etretin
Ro 10-1670
Ro 10-1670/000
Ro 13-7652
Ro-10-1670
Ro-10-1670/000
Ro-13-7652
S1368_Selleck
SAM002589973
SBB064171
SMR000499573
Soriatane
Soriatane (TN)
Soriatane, Acitretin
Spectrum5_002065
TMMP
U0279
UNII-LCH760E9T7
all-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid
all-trans-Acitretin
15tannic acidapproved, NutraceuticalPhase 4, Phase 3, Phase 21892
16
Folic Acidapproved, nutraceutical, vet_approvedPhase 4, Phase 3, Phase 2, Phase 1427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
17VaccinesPhase 4, Phase 26428
18Anti-Infective AgentsPhase 4, Phase 3, Phase 2, Phase 121402
19ImmunoglobulinsPhase 4, Phase 3, Phase 2, Phase 16045
20Adrenocorticotropic HormonePhase 4155
21Calcium, DietaryPhase 45525
22Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 2, Phase 110355
23Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 3, Phase 2, Phase 14295
24Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 1, Phase 212767
25AntibodiesPhase 4, Phase 3, Phase 2, Phase 16045
26Melanocyte-Stimulating HormonesPhase 4132
27Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 2, Phase 16260
28HormonesPhase 4, Phase 1, Phase 213979
29Antirheumatic AgentsPhase 4, Phase 3, Phase 2, Phase 110627
30Immunosuppressive AgentsPhase 4, Phase 3, Phase 2, Phase 112770
31Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 122776
32Gastrointestinal AgentsPhase 4, Phase 3, Phase 2, Phase 18109
33beta-endorphinPhase 4133
34Dermatologic AgentsPhase 4, Phase 3, Phase 2, Phase 15674
35Hormone AntagonistsPhase 4, Phase 1, Phase 212778
36AnalgesicsPhase 4, Phase 3, Phase 2, Phase 111287
37Angiogenesis InhibitorsPhase 4, Phase 3, Phase 2, Phase 14143
38Angiogenesis Modulating AgentsPhase 4, Phase 3, Phase 2, Phase 14072
39Anti-Bacterial AgentsPhase 4, Phase 3, Phase 2, Phase 110884
40Vitamin B ComplexPhase 4, Phase 3, Phase 2, Phase 14229
41Antimetabolites, AntineoplasticPhase 4, Phase 3, Phase 2, Phase 17171
42AntimetabolitesPhase 4, Phase 3, Phase 2, Phase 111774
43Folic Acid AntagonistsPhase 4, Phase 3, Phase 2, Phase 12200
44Nucleic Acid Synthesis InhibitorsPhase 4, Phase 3, Phase 2, Phase 14855
45Antibodies, MonoclonalPhase 4, Phase 3, Phase 2, Phase 13795
46glucocorticoidsPhase 4, Phase 1, Phase 24920
47Triamcinolone hexacetonidePhase 4482
48Triamcinolone diacetatePhase 4482
49triamcinolone acetonidePhase 4482
50Folinic AcidNutraceuticalPhase 4, Phase 3, Phase 2, Phase 13150

Interventional clinical trials:

(show top 50)    (show all 265)
idNameStatusNCT IDPhase
1Protocol for H.P. Acthar Gel in Moderately to Severely Active Psoriatic ArthritisUnknown statusNCT01939132Phase 4
2Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing SpondylitisUnknown statusNCT02132234Phase 4
3Sensitivity and Specificity of QuantiFeron -TB Gold Test (QFT-G)in Patients With PsoriasisUnknown statusNCT01223976Phase 4
4Safety and Efficacy of Gardasil in Females With Juvenile Idiopathic Arthritis (JIA)/Seronegative ArthritisUnknown statusNCT00573651Phase 4
5The Influence of Adalimumab on Cardiovascular and Metabolic Risk in PsoriasisUnknown statusNCT01088165Phase 4
6A Study in Participants With Psoriatic Arthritis Attending Dermatology ClinicsCompletedNCT02470481Phase 4
7Prevalence of Psoriatic Arthritis in Adults With Psoriasis: An Estimate From Dermatology PracticeCompletedNCT01147874Phase 4
8Study Evaluating Etanercept on Skin and Joint Disease in Psoriatic ArthritisCompletedNCT00245960Phase 4
9HUmira in Psoriatic ArthritisCompletedNCT01465438Phase 4
10REPArE: Rating Evaluations in Psoriatic Arthritis (PsA) With Etanercept (Enbrel®)CompletedNCT00127842Phase 4
11Tumor Necrosis Factors (TNF)-α Blockade for Psoriatic ArthritisCompletedNCT00432406Phase 4
12An Observational Study of Infliximab Injection in Ankylosing Spondylitis, Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis ParticipantsCompletedNCT00760669Phase 4
13Enbrel® in Psoriatic ArthritisCompletedNCT00111124Phase 4
14Study Evaluating Etanercept in Patients With Rheumatoid Arthritis(RA), Juvenile Idiopathic Arthritis (JIA), or Psoriatic Arthritis (PsA) in SpainCompletedNCT00195377Phase 4
15National Psoriasis Foundation - Dendritic Cell-Specific Transmembrane Protein (DC-Stamp) Biomarker StudyCompletedNCT01123265Phase 4
16Study Evaluating Etanercept and Methotrexate in Plaque PsoriasisCompletedNCT00161655Phase 4
17TNFalfa Blocking Treatment of SpondylarthropathiesCompletedNCT00133315Phase 4
18Evaluation of a Protocol for Dose Reduction in Patients With Spondylarthropathies and Clinical Remission With Anti-TNFCompletedNCT01604629Phase 4
19Centocor Microarray Study of PatientsCompletedNCT00462072Phase 4
20Controlled Study of Humira in Subjects With Chronic Plaque Psoriasis of the Hands and/or FeetCompletedNCT00735787Phase 4
21Study Evaluating Etanercept for the Treatment of Moderate to Severe PsoriasisCompletedNCT00663052Phase 4
22A Study on Assessment of STELARA and Tumor Necrosis Factor Alpha Inhibitor Therapies in Participants With Psoriatic ArthritisRecruitingNCT02627768Phase 4
23A Study of Subjects With Psoriatic Arthritis to Investigate the Effectiveness of Adalimumab Introduction Compared With Methotrexate Dose EscalationRecruitingNCT02814175Phase 4
24Study to Evaluate the Safety and Efficacy of Secukinumab 300 mg and 150 mg in Adult Patients With Active Psoriatic Arthritis (PsA) After 16 Weeks of Treatment Compared to PlaceboRecruitingNCT02798211Phase 4
25Assess the Injection Site Pain Associated With a New Etanercept Formulation in Adult Subjects With RA or PsARecruitingNCT02986139Phase 4
26Tracking Biologics Along the Silk RoadRecruitingNCT03006198Phase 4
27Biologic Treatment Registry Across CanadaRecruitingNCT00741793Phase 4
28Dosing of Intra-articular Triamcinolone Hexacetonide for Knee Synovitis in Chronic PolyarthritisRecruitingNCT02437461Phase 4
29Analysis of Birth Outcomes of Swedish, Danish and Finnish Women Exposed to Remicade With Inflammatory Bowel Disease, Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and PsoriasisActive, not recruitingNCT00658827Phase 4
30Psoriasis Longitudinal Assessment and Registry (PSOLAR)Active, not recruitingNCT00508547Phase 4
31The NOR-SWITCH StudyActive, not recruitingNCT02148640Phase 4
32An Investigator Initiated Open Label Study Evaluating the Efficacy and Tolerability of Oral Apremilast for the Treatment of Nail PsoriasisNot yet recruitingNCT03022617Phase 4
33A Study to Assess the Safety and Effectiveness of Golimumab in Filipino Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing SpondylitisWithdrawnNCT01692457Phase 4
34Treatment With Apremilast in Patients With Psoriatic ArthritisWithdrawnNCT02558361Phase 4
35Study of Anti-Viral Prophylaxis for HBsAg(+) or HBcAb(+)/HBsAb(-) Patients Starting Anti-TNFαUnknown statusNCT01694264Phase 3
36Certolizumab Pegol in Subjects With Adult Onset Active and Progressive Psoriatic ArthritisCompletedNCT01087788Phase 3
37A Study of the Safety and Effectiveness of Infliximab for the Treatment of Psoriatic ArthritisCompletedNCT00051623Phase 3
38TIght COntrol of Psoriatic ArthritisCompletedNCT01106079Phase 3
39A Study of the Safety and Effectiveness of Ustekinumab in Patients With Psoriatic ArthritisCompletedNCT01009086Phase 3
40A Study of the Safety and Efficacy of Golimumab in Patients With Active Psoriatic ArthritisCompletedNCT00265096Phase 3
41A Study of the Safety and Efficacy of Ustekinumab in Patients With Psoriatic Arthritis With and Without Prior Exposure to Anti-TNF AgentsCompletedNCT01077362Phase 3
42Safety and Efficacy Study of Adalimumab in Patients With Active Psoriatic Arthritis (PsA)CompletedNCT00235885Phase 3
43Study of Efficacy and Safety of Brodalumab in Subjects With Psoriatic ArthritisCompletedNCT02024646Phase 3
44Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Naïve Disease (RESPOND) (Study P04422)CompletedNCT00367237Phase 3
45Efficacy And Safety Of Tofacitinib In Psoriatic Arthritis: Comparator StudyCompletedNCT01877668Phase 3
46Tofacitinib In Psoriatic Arthritis Subjects With Inadequate Response to TNF InhibitorsCompletedNCT01882439Phase 3
47Efficacy at 24 Weeks and Long Term Safety, Tolerability and Efficacy up to 2 Years of Secukinumab (AIN457) in Patients With Active Psoriatic Arthritis (PsA)CompletedNCT01392326Phase 3
48Safety and Efficacy of Adalimumab in Patients With Moderate to Severely Active Psoriatic ArthritisCompletedNCT00195689Phase 3
49Study to Evaluate the Ability of Subjects With Rheumatoid Arthritis or Psoriatic Arthritis to Effectively Use a Reusable Autoinjector to Self-inject EtanerceptCompletedNCT01901185Phase 3
50Does Etanercept Influence Tweak Modulation of Inflammation During Inflammatory Rheumatisms (Psoriatic Arthritis and Rheumatoid Arthritis)?CompletedNCT02164214Phase 3

Search NIH Clinical Center for Psoriatic Arthritis

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: arthritis, psoriatic

Genetic Tests for Psoriatic Arthritis

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Genetic tests related to Psoriatic Arthritis:

id Genetic test Affiliating Genes
1 Psoriatic Arthritis, Susceptibility to27

Anatomical Context for Psoriatic Arthritis

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MalaCards organs/tissues related to Psoriatic Arthritis:

36
Skin, Testes, Bone, Liver, Endothelial, T cells, Placenta

Publications for Psoriatic Arthritis

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Articles related to Psoriatic Arthritis:

(show top 50)    (show all 1007)
idTitleAuthorsYear
1
Early recognition and detection of juvenile psoriatic arthritis: a call for a standardized approach to screening. (28044348)
2017
2
Rapid dactylitis resolution in a patient with psoriatic arthritis after treatment with ustekinumab. (28073691)
2017
3
Increased prevalence of coronary plaque in patients with psoriatic arthritis without prior diagnosis of coronary artery disease. (28052860)
2017
4
Pregnancy Outcomes in Patients with Psoriatic Arthritis. (28042130)
2017
5
Radiographic scoring instruments have moderate sensitivity but high specificity for detecting change in axial psoriatic arthritis. (28085226)
2017
6
ERAP1 and ERAP2 Gene Variations Influence the Risk of Psoriatic Arthritis in Romanian Population. (28083616)
2017
7
Umbilical Plaque in Psoriatic Arthritis. (28090061)
2017
8
Effectiveness of conventional disease-modifying antirheumatic drugs in psoriatic arthritis: A systematic review. (28089501)
2017
9
Changes in Treatment Patterns in Patients with Psoriatic Arthritis Initiating Biologic and Nonbiologic Therapy in a Clinical Registry. (28089969)
2017
10
New GRAPPA and EULAR recommendations for the management of psoriatic arthritis: Process and challenges faced. (28077693)
2017
11
Impaired myocardial deformation in psoriatic arthritis patients assessment by speckle tracking echocardiography. (27606472)
2016
12
Symptomless Pulmonary Cryptococcosis in a Psoriatic Arthritis Patient during Infliximab Therapy. (27081286)
2016
13
Incidence and Prevalence of Cardiovascular Risk Factors Among Patients With Rheumatoid Arthritis, Psoriasis, or Psoriatic Arthritis. (27998029)
2016
14
The Psoriatic Arthritis Impact of Disease 12-item questionnaire: equivalence, reliability, validity, and feasibility of the touch-screen administration versus the paper-and-pencil version. (27143906)
2016
15
Spondyloarthropathies: IL-6 blockade in psoriatic arthritis - a new therapeutic option? (27215204)
2016
16
Psoriatic arthritis and psoriasis: differential diagnosis. (27156076)
2016
17
Association of IL1I9 (-511 A/C) and IL6 (-174 G > C) polymorphisms with higher disease activity and clinical pattern of psoriatic arthritis. (27188858)
2016
18
Association of Toll-like receptor 4 (TLR4) with chronic plaque type psoriasis and psoriatic arthritis. (26830904)
2016
19
The influence of obesity on response to tumour necrosis factor-I+ inhibitors in psoriatic arthritis: results from the DANBIO and ICEBIO registries. (27651526)
2016
20
Reduced CLEC9A expression in synovial tissue of psoriatic arthritis patients after adalimumab therapy. (27179104)
2016
21
Risk of cardiovascular morbidity in patients with psoriatic arthritis: A meta-analysis of observational studies. (27111228)
2016
22
Incidence and Prognosis of Psoriasis and Psoriatic Arthritis in Patients Undergoing Bariatric Surgery. (28002543)
2016
23
Anti-MDA5 dermatomyositis mimicking psoriatic arthritis. (28040421)
2016
24
Previously undiagnosed diastematomyelia with bony spur as a cause of back pain in a 49-year-old patient with known psoriatic arthritis. (27665760)
2016
25
Subacute thyroiditis in psoriatic arthritis treated by adalimumab. (27825573)
2016
26
Prologue: 2015 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA). (27134267)
2016
27
Aortitis due to giant cell arteritis and psoriatic arthritis: An uncommon association. (27131857)
2016
28
An ultrasonographic study of enthesis in early psoriatic arthritis patients naive to traditional and biologic DMARDs treatment. (27600991)
2016
29
Serum Interleukin-18, Fetuin-A, Soluble Intercellular Adhesion Molecule-1, and Endothelin-1 in Ankylosing Spondylitis, Psoriatic Arthritis, and SAPHO Syndrome. (27527149)
2016
30
Limited association between scalp psoriasis and psoriatic arthritis severity and treatment response. (27606545)
2016
31
Disease-modifying antirheumatic drugs improve cardiovascular autonomic neuropathy in psoriatic arthritis. (27047572)
2016
32
Maintenance of remission and monotherapy status over 66 months in patients with psoriatic arthritis receiving etanercept. (27606973)
2016
33
Detection of subclinical ultrasound enthesopathy and nail disease in patients at risk of psoriatic arthritis. (27932277)
2016
34
Polyarteritis nodosa. Diagnostic challenges in a patient with cutaneous vasculitis, psoriasis, psoriatic arthritis and pancytopenia: fatal progression after treatment with G-CSF. (27123310)
2016
35
Psoriatic arthritis in Japan: difference in clinical features and approach to precision medicine. (27586804)
2016
36
Psoriatic arthritis treated by anti-TNFs: a monocentric trial of 102 cases in Auvergne (France). (27607233)
2016
37
Superficial spreading melanoma in a psoriatic plaque of a patient with psoriatic arthritis. (27099025)
2016
38
Cartilage collagen type II seromarker patterns in axial spondyloarthritis and psoriatic arthritis: associations with disease activity, smoking and HLA-B27. (26620690)
2016
39
No Evidence for Depression Screening in Rheumatoid Arthritis, Psoriasis, or Psoriatic Arthritis. (27134277)
2016
40
Sensitivity of the GEPARD Patient Questionnaire to Identify Psoriatic Arthritis in Patients with Psoriasis in Daily Practice: The GEPARD-Life Study. (27603046)
2016
41
Autoimmune Arthritides, Rheumatoid Arthritis, Psoriatic Arthritis, or Peripheral Spondyloarthropathy, Following Lyme Disease. (27636905)
2016
42
Certain class I HLA alleles and haplotypes implicated in susceptibility play a role in determining specific features of the psoriatic arthritis phenotype. (25261574)
2016
43
Comparison of Etanercept Monotherapy and Combination Therapy with Methotrexate in Psoriatic Arthritis: Results from 2 Clinical Trials. (27134249)
2016
44
A national survey on the management of psoriatic arthritis using the Delphi method. (27607572)
2016
45
Associations between five important domains of health and the Patient Acceptable Symptom State in rheumatoid arthritis and psoriatic arthritis: A cross sectional study of 977 patients. (27998030)
2016
46
Defining Low Disease Activity States in Psoriatic Arthritis Using Novel Composite Disease Instruments. (27587014)
2016
47
Development of Eosinophilic Fasciitis during Infliximab Therapy for Psoriatic Arthritis. (27293946)
2016
48
Orthopaedic interventions in patients with psoriatic arthritis: a descriptive report from the SPAR cohort. (27651927)
2016
49
Efficacy and safety of anti-TNF therapies in psoriatic arthritis: an observational study from the British Society for Rheumatology Biologics Register. (28003495)
2016
50
Case of Legionella pneumophila pneumonia (legionellosis) developed in a psoriatic arthritis patient receiving adalimumab. (27651216)
2016

Variations for Psoriatic Arthritis

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Clinvar genetic disease variations for Psoriatic Arthritis:

5
id Gene Variation Type Significance SNP ID Assembly Location
1LTANM_001159740.2(LTA): c.-9-198A> GSNVrisk factorrs909253GRCh37Chr 6, 31540313: 31540313

Expression for genes affiliated with Psoriatic Arthritis

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Search GEO for disease gene expression data for Psoriatic Arthritis.

Pathways for genes affiliated with Psoriatic Arthritis

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Pathways related to Psoriatic Arthritis according to GeneCards Suite gene sharing:

(show all 33)
idSuper pathwaysScoreTop Affiliating Genes
19.9NOD2, TNF, TNFRSF1A
29.9TNFRSF11B, TNFSF11
39.9TNF, TNFRSF1A, TNFRSF1B
49.9TNF, TNFRSF1A, TNFRSF1B
5
Show member pathways
9.9TNF, TNFRSF1A, TNFRSF1B
69.8LTA, TNF, TNFRSF1A, TNFRSF1B
7
Show member pathways
9.8LTA, TNF, TNFRSF1A, TNFRSF1B
89.8IL1B, SELE, TNF
9
Show member pathways
9.7IL1B, TNF, TNFRSF11B
109.7IL13, IL1B, TNF
11
Show member pathways
9.7TNF, TNFRSF1A, TNFRSF1B, TNFSF11
129.7IL1B, NOD2, TNF, TNFRSF1A
139.6HLA-B, HLA-C, LTA, TNF, TNFRSF1A
149.6IL1B, MMP3, TNF, TNFSF11
159.6IL13, IL1B, LTA, TNF
169.5IL1B, TNF, TNFRSF11B, TNFSF11
179.5COMP, IL1B, SELE, TNF
18
Show member pathways
9.5IL1B, LTA, TNF, TNFRSF1A, TNFRSF1B
19
Show member pathways
9.5IL1B, LTA, TNF, TNFRSF1A, TNFRSF1B
209.5CD58, HLA-B, HLA-C, SELE
21
Show member pathways
9.5LTA, TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B
229.5IL1B, LTA, TNF, TNFRSF1A, TNFSF11
239.3IL13, IL1B, LTA, TNF, TNFSF11
249.3IL1B, TNF, TNFRSF11B, TNFRSF1A, TNFSF11
25
Show member pathways
9.2HLA-B, HLA-C, IL13, IL1B, LTA, TNF
26
Show member pathways
9.0HLA-C, LTA, TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B
279.0IL1B, PTPN22, TNF, TNFRSF1A, TNFRSF1B, TNFSF11
28
Show member pathways
9.0HLA-B, HLA-C, IL13, IL1B, LTA, TNF
29
Show member pathways
8.9HLA-B, HLA-C, IL13, IL1B, LTA, MICA
308.8IL1B, LTA, MMP3, NOD2, SELE, TNF
31
Show member pathways
8.8IL1B, LTA, TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B
32
Show member pathways
8.7IL13, IL1B, LTA, PTPN22, TNF, TNFRSF1A
33
Show member pathways
7.4CRP, HLA-B, HLA-C, IL13, IL1B, LTA

GO Terms for genes affiliated with Psoriatic Arthritis

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Cellular components related to Psoriatic Arthritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class I protein complexGO:004261210.9HLA-B, HLA-C
2membrane raftGO:004512110.4SELE, TNF, TNFRSF1A, TNFRSF1B
3cell surfaceGO:00099869.9CD58, HLA-B, HLA-C, MICA, NOD2, TNF
4extracellular regionGO:00055768.5COMP, CRP, IL13, IL1B, MMP3, S100A12
5extracellular spaceGO:00056158.5COMP, CRP, IL13, IL1B, LTA, MICA
6plasma membraneGO:00058867.6CD58, HLA-B, HLA-C, LTA, MICA, NOD2

Biological processes related to Psoriatic Arthritis according to GeneCards Suite gene sharing:

(show all 40)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chronic inflammatory response to antigenic stimulusGO:000287610.9LTA, TNF
2positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292510.9LTA, TNF
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentGO:000248010.9HLA-B, HLA-C
4death-inducing signaling complex assemblyGO:007155010.9TNF, TNFRSF1A
5cellular response to muramyl dipeptideGO:007122510.9NOD2, PTPN22
6negative regulation of lipid storageGO:001088810.8CRP, TNF
7positive regulation of ceramide biosynthetic processGO:200030410.8TNF, TNFRSF1A
8chronic inflammatory response to antigenic stimulusGO:000243910.8IL1B, TNF
9positive regulation of calcidiol 1-monooxygenase activityGO:006055910.8IL1B, TNF
10positive regulation of chemokine biosynthetic processGO:004508010.8IL1B, TNF
11positive regulation of fever generationGO:003162210.8IL1B, TNF
12positive regulation of heterotypic cell-cell adhesionGO:003411610.8IL1B, TNF
13leukocyte tethering or rollingGO:005090110.8SELE, TNF
14defense response to Gram-positive bacteriumGO:005083010.7CRP, LTA, TNF
15antigen processing and presentationGO:001988210.7HLA-B, HLA-C, MICA
16cellular response to organic cyclic compoundGO:007140710.7IL1B, NOD2, TNF
17intrinsic apoptotic signaling pathway in response to DNA damageGO:000863010.7TNF, TNFRSF1A, TNFRSF1B
18apoptotic signaling pathwayGO:009719010.6TNF, TNFRSF11B, TNFRSF1B
19positive regulation of interferon-gamma productionGO:003272910.6IL1B, LTA, TNF
20sequestering of triglycerideGO:003073010.6IL1B, TNF
21positive regulation of interleukin-6 productionGO:003275510.6IL1B, NOD2, TNF
22positive regulation of interleukin-8 productionGO:003275710.6IL1B, NOD2, TNF
23lipopolysaccharide-mediated signaling pathwayGO:003166310.5IL1B, PTPN22, TNF
24positive regulation of membrane protein ectodomain proteolysisGO:005104410.5IL1B, TNF, TNFRSF1B
25defense responseGO:000695210.5NOD2, TNF, TNFRSF1A, TNIP1
26regulation of establishment of endothelial barrierGO:190314010.5IL1B, TNF, TNFRSF1A
27cellular response to mechanical stimulusGO:007126010.4IL13, IL1B, TNFRSF1A
28positive regulation of inflammatory responseGO:005072910.4S100A12, TNFRSF1A, TNIP1
29positive regulation of MAP kinase activityGO:004340610.4S100A12, TNF, TNFSF11
30positive regulation of ERK1 and ERK2 cascadeGO:007037410.4IL1B, NOD2, PTPN22, TNF
31positive regulation of JNK cascadeGO:004633010.3IL1B, NOD2, TNF, TNFSF11
32regulation of cell proliferationGO:004212710.2TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B
33leukocyte migrationGO:005090010.2CD58, IL1B, SELE, TNF
34defense response to bacteriumGO:004274210.2MICA, NOD2, S100A12, TNF, TNFRSF1A
35immune responseGO:000695510.0IL13, TNFRSF11B, TNFRSF1A, TNFRSF1B, TNFSF11
36positive regulation of NF-kappaB transcription factor activityGO:00510929.9IL1B, NOD2, S100A12, TNF, TNFSF11
37positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431239.8IL1B, NOD2, S100A12, TNF, TNFRSF1A, TNFSF11
38tumor necrosis factor-mediated signaling pathwayGO:00332099.2LTA, TNF, TNFRSF11B, TNFRSF1A, TNFRSF1B, TNFSF11
39response to lipopolysaccharideGO:00324969.1IL13, IL1B, LTA, PTPN22, SELE, TNFRSF11B
40inflammatory responseGO:00069548.7CRP, IL13, IL1B, S100A12, SELE, TNF

Molecular functions related to Psoriatic Arthritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1antigen bindingGO:000382310.5HLA-B, HLA-C, MICA
2tumor necrosis factor receptor bindingGO:000516410.3LTA, TNF, TNFSF11
3tumor necrosis factor-activated receptor activityGO:00050319.8TNFRSF11B, TNFRSF1A, TNFRSF1B
4cytokine activityGO:00051259.5IL13, IL1B, LTA, TNF, TNFRSF11B, TNFSF11

Sources for Psoriatic Arthritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet