MCID: PSR016
MIFTS: 17

Psoriatic Juvenile Idiopathic Arthritis malady

Summaries for Psoriatic Juvenile Idiopathic Arthritis

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32MalaCards
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MalaCards: Psoriatic Juvenile Idiopathic Arthritis is related to arthritis and psoriatic arthritis. An important gene associated with Psoriatic Juvenile Idiopathic Arthritis is MEFV (Mediterranean fever), and among its related pathways are Toll-Like receptor Signaling Pathways and Immune System. The compounds endotoxin and mevalonate have been mentioned in the context of this disorder. Related mouse phenotype immune system.

Aliases & Classifications for Psoriatic Juvenile Idiopathic Arthritis

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42NIH Rare Diseases
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Aliases & Descriptions:

psoriatic juvenile idiopathic arthritis 42


Related Diseases for Psoriatic Juvenile Idiopathic Arthritis

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Psoriatic Juvenile Idiopathic Arthritis:



Diseases related to psoriatic juvenile idiopathic arthritis

Clinical Features for Psoriatic Juvenile Idiopathic Arthritis

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Drugs & Therapeutics for Psoriatic Juvenile Idiopathic Arthritis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Psoriatic Juvenile Idiopathic Arthritis

Search NIH Clinical Center for Psoriatic Juvenile Idiopathic Arthritis

Search CenterWatch for Psoriatic Juvenile Idiopathic Arthritis

Genetic Tests for Psoriatic Juvenile Idiopathic Arthritis

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Anatomical Context for Psoriatic Juvenile Idiopathic Arthritis

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Animal Models for Psoriatic Juvenile Idiopathic Arthritis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Psoriatic Juvenile Idiopathic Arthritis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.0NOD2, MEFV, PSTPIP1, NLRP3

Publications for Psoriatic Juvenile Idiopathic Arthritis

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Genetic Variations for Psoriatic Juvenile Idiopathic Arthritis

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Expression for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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Pathways for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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52R&D Systems, 53Reactome, 37NCBI BioSystems Database, 29KEGG
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Compounds for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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44Novoseek
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Compounds related to Psoriatic Juvenile Idiopathic Arthritis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1endotoxin449.4NOD2, MEFV
2mevalonate448.8MEFV, NLRP3

GO Terms for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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16Gene Ontology
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Cellular components related to Psoriatic Juvenile Idiopathic Arthritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:0058298.0NOD2, MEFV, PSTPIP1, NLRP3

Biological processes related to Psoriatic Juvenile Idiopathic Arthritis according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of interleukin-12 productionGO:0326959.6NOD2, MEFV
2detection of biotic stimulusGO:0095959.3NOD2, NLRP3
3positive regulation of interleukin-1 beta secretionGO:0507189.2NLRP3, NOD2
4protein oligomerizationGO:0512599.2NOD2, NLRP3
5negative regulation of inflammatory responseGO:0507289.1MEFV, NLRP3
6positive regulation of NF-kappaB transcription factor activityGO:0510929.1NOD2, NLRP3
7negative regulation of NF-kappaB transcription factor activityGO:0320889.0NLRP3, NOD2
8defense responseGO:0069528.8NLRP3, NOD2
9nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayGO:0358728.2NOD2, MEFV, PSTPIP1, NLRP3
10innate immune responseGO:0450878.2NLRP3, PSTPIP1, MEFV, NOD2

Molecular functions related to Psoriatic Juvenile Idiopathic Arthritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1peptidoglycan bindingGO:0428349.1NOD2, NLRP3

Products for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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  • Antibodies
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  • Antibodies

Sources for Psoriatic Juvenile Idiopathic Arthritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet