MCID: PSR016
MIFTS: 19

Psoriatic Juvenile Idiopathic Arthritis malady

Summaries for Psoriatic Juvenile Idiopathic Arthritis

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33MalaCards
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MalaCards: Psoriatic Juvenile Idiopathic Arthritis is related to arthritis and psoriatic arthritis. An important gene associated with Psoriatic Juvenile Idiopathic Arthritis is MEFV (Mediterranean fever), and among its related pathways are Toll-Like receptor Signaling Pathways and Immune System. The compounds endotoxin and mevalonate have been mentioned in the context of this disorder. Related mouse phenotype immune system.

Aliases & Classifications for Psoriatic Juvenile Idiopathic Arthritis

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43NIH Rare Diseases
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Aliases & Descriptions:

psoriatic juvenile idiopathic arthritis 43


Related Diseases for Psoriatic Juvenile Idiopathic Arthritis

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Psoriatic Juvenile Idiopathic Arthritis:



Diseases related to psoriatic juvenile idiopathic arthritis

Clinical Features for Psoriatic Juvenile Idiopathic Arthritis

Drugs & Therapeutics for Psoriatic Juvenile Idiopathic Arthritis

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5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Psoriatic Juvenile Idiopathic Arthritis

Search CenterWatch for Psoriatic Juvenile Idiopathic Arthritis

Genetic Tests for Psoriatic Juvenile Idiopathic Arthritis

Anatomical Context for Psoriatic Juvenile Idiopathic Arthritis

Animal Models for Psoriatic Juvenile Idiopathic Arthritis or affiliated genes

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37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Psoriatic Juvenile Idiopathic Arthritis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.0NOD2, MEFV, PSTPIP1, NLRP3

Publications for Psoriatic Juvenile Idiopathic Arthritis

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51PubMed
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Articles related to Psoriatic Juvenile Idiopathic Arthritis:

idTitleAuthorsYear
1
Psoriatic juvenile idiopathic arthritis associated with uveitis: a case report. (24191219)
2013
2
Adalimumab: long-term safety in 23 458 patients from global clinical trials in rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis and Crohn's disease. (22562972)
2013
3
Efficacy and safety of open-label etanercept on extended oligoarticular juvenile idiopathic arthritis, enthesitis-related arthritis and psoriatic arthritis: part 1 (week 12) of the CLIPPER study. (23696632)
2013
4
Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis. (21281511)
2011
5
Juvenile psoriatic arthritis: longterm outcome and differentiation from other subtypes of juvenile idiopathic arthritis. (19208605)
2009
6
Comparison of patients with juvenile psoriatic arthritis and nonpsoriatic juvenile idiopathic arthritis: how different are they? (19648305)
2009
7
Autoinflammatory genes and susceptibility to psoriatic juvenile idiopathic arthritis. (18576390)
2008

Genetic Variations for Psoriatic Juvenile Idiopathic Arthritis

Expression for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

Search GEO for disease gene expression data for Psoriatic Juvenile Idiopathic Arthritis.

Pathways for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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53R&D Systems, 54Reactome, 38NCBI BioSystems Database, 30KEGG
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Compounds for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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45Novoseek
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Compounds related to Psoriatic Juvenile Idiopathic Arthritis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1endotoxin459.4NOD2, MEFV
2mevalonate458.8MEFV, NLRP3

GO Terms for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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16Gene Ontology
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Cellular components related to Psoriatic Juvenile Idiopathic Arthritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:0058298.0NOD2, MEFV, PSTPIP1, NLRP3

Biological processes related to Psoriatic Juvenile Idiopathic Arthritis according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of interleukin-12 productionGO:0326959.6NOD2, MEFV
2detection of biotic stimulusGO:0095959.3NOD2, NLRP3
3positive regulation of interleukin-1 beta secretionGO:0507189.2NLRP3, NOD2
4protein oligomerizationGO:0512599.2NOD2, NLRP3
5negative regulation of inflammatory responseGO:0507289.1MEFV, NLRP3
6positive regulation of NF-kappaB transcription factor activityGO:0510929.1NOD2, NLRP3
7negative regulation of NF-kappaB transcription factor activityGO:0320889.0NLRP3, NOD2
8defense responseGO:0069528.8NLRP3, NOD2
9nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayGO:0358728.2NOD2, MEFV, PSTPIP1, NLRP3
10innate immune responseGO:0450878.2NLRP3, PSTPIP1, MEFV, NOD2

Molecular functions related to Psoriatic Juvenile Idiopathic Arthritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1peptidoglycan bindingGO:0428349.1NOD2, NLRP3

Products for genes affiliated with Psoriatic Juvenile Idiopathic Arthritis

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  • Proteins
  • Lysates
  • Antibodies

Sources for Psoriatic Juvenile Idiopathic Arthritis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet