MCID: PSY012
MIFTS: 25

Psychogenic Movement

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Psychogenic Movement

MalaCards integrated aliases for Psychogenic Movement:

Name: Psychogenic Movement 50
Psychogenic Movement Disorders 55
Psychogenic Dystonia 55
Pseudodystonia 69

Characteristics:

Orphanet epidemiological data:

55
psychogenic movement disorders
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 55  
Rare neurological diseases


External Ids:

Orphanet 55 ORPHA71519
UMLS via Orphanet 70 C3267131
ICD10 via Orphanet 33 F44.4
SNOMED-CT via HPO 65 22325002
UMLS 69 C0752208

Summaries for Psychogenic Movement

NINDS : 50 Psychogenic movement is an unwanted muscle movement such as a spasm or tremor that is caused by an underlying psychological condition. Psychogenic movement can involve any part of the body and resemble the same muscle movements that occur with a biological condition or structural abnormality. Most psychogenic movement is involuntary—done without being consciously initiated by the individual. Psychogenic movement may develop as part of a conversion disorder (in which a psychological event causes physical symptoms with no known medical cause). It also may result from a somatoform disorder (characterized predominantly by multi-system symptoms that are associated with distress and/or dysfunction), factitious disorder (an illness that simulates symptoms for psychological reasons), or malingering (not characterized as a psychiatric disorder but where illness is pretended as a way to achieve a secondary goal such as the acquisition of drugs or disability benefits). Unlike movement disorders caused by biological or structural conditions, psychogenic movement disorders commonly develop suddenly, progress rapidly to maximum severity, may increase in intensity, and come and go with complete or partial remissions.  The movement may be less when the person is distracted, and the severity of symptoms varies among individuals.  The course of the psychological condition may be short-lived or lead to chronic disability. Psychogenic movement is uncommon before the age of 10 years. In children, the dominant limb is most often affected, while adults most frequently see movement in the nondominant limb. Psychogenic movement disorders include: Psychogenic tremor (also called functional tremor) can appear as any form of tremor movement. Characteristics may vary but generally include sudden onset and remission, increased incidence with stress, change in tremor direction and/or body part affected, and greatly decreased or disappearing tremor activity when the person is being distracted. Many individuals with psychogenic tremor have a conversion disorder. Psychogenic dystonia involves involuntary muscle contractions that cause slow, repetitive movements or abnormal postures that are often severely painful. Onset may be abrupt or appear as part of a recurring attack. Psychogenic dystonia typically involves fixed postures, particularly from the start, whereas dystonia caused by a muscle or structural abnormality tends to involve more mobility and be action induced. Psychogenic myoclonus refers to sudden, involuntary muscle contractions (twitches) or jerking of a muscle or group of muscles that are caused by a psychological condition. Myoclonic jerks may occur alone or in sequence, in a pattern or without pattern. Increased startle or startle-like movements are frequent. Psychogenic myoclonus may occur spontaneously or be generated by an action or reflex. The twitching cannot be controlled by the person experiencing it. Psychogenic parkinsonism involves rigid movements that are extremely slow and often associated with a great sense of effort and rapid onset of severe fatigue. Individuals with psychogenic parkinsonism may also have tremor. Symptoms are usually seen on both sides of the body. Psychogenic gait disturbances feature unusual patterns of stance and gait. Individuals may stagger or veer from side to side when walking and appear to be losing their balance, but only rarely fall. Sudden knee buckling without falling is common.

MalaCards based summary : Psychogenic Movement, also known as psychogenic movement disorders, is related to dystonia and aging, and has symptoms including gait disturbance, neurological speech impairment and abnormality of movement. The drugs Acetylcholine and abobotulinumtoxinA have been mentioned in the context of this disorder. Affiliated tissues include brain and testes.

Related Diseases for Psychogenic Movement

Diseases related to Psychogenic Movement via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 dystonia 10.0
2 aging 9.8
3 myoclonus 9.8
4 tremor 9.8

Symptoms & Phenotypes for Psychogenic Movement

Human phenotypes related to Psychogenic Movement:

55 31
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 gait disturbance 55 31 frequent (33%) Frequent (79-30%) HP:0001288
2 neurological speech impairment 55 31 frequent (33%) Frequent (79-30%) HP:0002167
3 abnormality of movement 55 Very frequent (99-80%)

Drugs & Therapeutics for Psychogenic Movement

Drugs for Psychogenic Movement (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved Phase 4 51-84-3 187
2 abobotulinumtoxinA Phase 4
3 Cholinergic Agents Phase 4
4 Neuromuscular Agents Phase 4
5 Neurotransmitter Agents Phase 4
6 onabotulinumtoxinA Phase 4
7 Peripheral Nervous System Agents Phase 4
8 Botulinum Toxins Phase 4
9 Botulinum Toxins, Type A Phase 4

Interventional clinical trials:

(show all 14)

# Name Status NCT ID Phase Drugs
1 OnabotulinumtoxinA in the Management of Psychogenic Dystonia Recruiting NCT02618889 Phase 4
2 rTMS Effect in Functional Psychogenic Movement Disorders Applied Alone Then Combined With Hypnotherapy Unknown status NCT02471066 Phase 2, Phase 3
3 Psychiatric Correlates of Psychogenic Movement Disorder and Non-Epileptic Seizure Completed NCT00255411
4 Treatment for Psychogenic Disorders Completed NCT00314444
5 Neurophysiological Studies in Patients With Paroxysmal Hyperkinetic Movement Disorders Completed NCT00056888
6 Treatment of Functional Movement Disorders With Psychotherapy Completed NCT01778517
7 Physiology of Weakness in Movement Disorders Completed NCT00307346
8 Brain Activity in People With Functional Movement Disorders Completed NCT00448084
9 Single Photon Emission Computed Tomography (SPECT) to Study Paroxysmal Hyperkinetic Movement Disorders Completed NCT00051337
10 Feasibility Study of Physiotherapy for Functional Motor Symptoms Completed NCT02275000
11 Neurobiology of Psychogenic Movement Disorder and Non-Epileptic Seizures Recruiting NCT00500994
12 Modulating Movement Intention Recruiting NCT03233399
13 Subjective Perception of Motor Control During Psychogenic Disorders Recruiting NCT02843932
14 Embodied Virtual Reality Therapy for Functional Neurological Symptom/ Conversion Disorder Recruiting NCT02764476

Search NIH Clinical Center for Psychogenic Movement

Genetic Tests for Psychogenic Movement

Anatomical Context for Psychogenic Movement

MalaCards organs/tissues related to Psychogenic Movement:

38
Brain, Testes

Publications for Psychogenic Movement

Articles related to Psychogenic Movement:

(show all 30)
# Title Authors Year
1
Psychogenic Movement Disorders and Dopamine Transporter Scans: Still a Clinical Diagnosis? ( 27889083 )
2017
2
The most promising advances in our understanding and treatment of functional (psychogenic) movement disorders. ( 28709746 )
2017
3
Personality traits in psychogenic nonepileptic seizures (PNES) and psychogenic movement disorder (PMD): Neuroticism and perfectionism. ( 28606495 )
2017
4
Psychodynamic Psychotherapy for Functional (Psychogenic) Movement Disorders. ( 28122424 )
2017
5
Hyperkinetic psychogenic movement disorders remain a diagnosis at first sight. ( 27913698 )
2017
6
Examiner manoeuvres 'sensory tricks' in functional (psychogenic) movement disorders. ( 27986829 )
2016
7
Deep brain stimulation of a patient with psychogenic movement disorder. ( 27990313 )
2016
8
Gender and Age Determinants of Psychogenic Movement Disorders: A Clinical Profile of 73 Patients. ( 26757796 )
2016
9
Psychogenic movement disorder in human T-lymphotropic virus type 1 associated myelopathy. ( 26603645 )
2016
10
Cranial functional (psychogenic) movement disorders. ( 26581970 )
2015
11
Functional (psychogenic) movement disorders - Clinical presentations. ( 26365778 )
2015
12
Functional or psychogenic movement disorders: an endless enigmatic tale. ( 25774148 )
2015
13
Psychogenic movement disorders. ( 25432730 )
2015
14
Paroxysmal non-kinesigenic dyskinesia, post-streptococcal syndromes and psychogenic movement disorders: a diagnostic challenge. ( 25795754 )
2015
15
Mitchell's case of "pendulum spasms": psychogenic movement disorder considered as male hysteria. ( 25628430 )
2015
16
Functional (psychogenic) movement disorders associated with normal scores in psychological questionnaires: A case control study. ( 26113484 )
2015
17
Phenotype-specific diagnosis of functional (psychogenic) movement disorders. ( 25900093 )
2015
18
Speech and voice disorders in patients with psychogenic movement disorders. ( 26194199 )
2015
19
Electrophysiological evaluation of psychogenic movement disorders. ( 26403429 )
2015
20
Reply to: psychogenic movement disorders: what's in a name? ( 25308926 )
2014
21
Psychogenic movement disorders: an unusual presentation in childhood with improvement after placebo test. ( 25252240 )
2014
22
Psychogenic nonepileptic seizures and psychogenic movement disorders: two sides of the same coin? ( 25337733 )
2014
23
The clinical features of psychogenic movement disorders resembling tics. ( 24259592 )
2014
24
Immediate vs. delayed treatment of psychogenic movement disorders with short term psychodynamic psychotherapy: randomized clinical trial. ( 24120952 )
2014
25
Treatment of functional (psychogenic) movement disorders. ( 24356785 )
2014
26
Clinical neurophysiology of psychogenic movement disorders: How to diagnose psychogenic tremor and myoclonus. ( 25306082 )
2014
27
"Psychogenic movement disorders": they are what they are. ( 24797587 )
2014
28
Functional/psychogenic movement disorders: do we know what they are? ( 25284581 )
2014
29
Loss of sensory attenuation in patients with functional (psychogenic) movement disorders. ( 25161293 )
2014
30
Psychogenic movement disorders. ( 24092294 )
2013

Variations for Psychogenic Movement

Expression for Psychogenic Movement

Search GEO for disease gene expression data for Psychogenic Movement.

Pathways for Psychogenic Movement

GO Terms for Psychogenic Movement

Sources for Psychogenic Movement

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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