MCID: PSY004
MIFTS: 61

Psychotic Disorder malady

Mental diseases, Neuronal diseases categories
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Summaries for Psychotic Disorder

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MedlinePlus:33 Mental disorders include a wide range of problems, including anxiety disorders, including panic disorder, obsessive-compulsive disorder, post-traumatic stress disorder, and phobias bipolar disorder depression mood disorders personality disorders psychotic disorders, including schizophrenia there are many causes of mental disorders. your genes and family history may play a role. your life experiences, such as stress or a history of abuse, may also matter. biological factors can also be part of the cause. a traumatic brain injury can lead to a mental disorder. a mother's exposure to viruses or toxic chemicals while pregnant may play a part. other factors may increase your risk, such as use of illegal drugs or having a serious medical condition like cancer. medications and counseling can help many mental disorders.

MalaCards based summary: Psychotic Disorder, also known as psychotic disorders, is related to schizoaffective disorder and amyotrophic lateral sclerosis type 14. An important gene associated with Psychotic Disorder is MOG (myelin oligodendrocyte glycoprotein), and among its related pathways are Phenylalanine metabolism and Tyrosine metabolism p.1 dopamine . The drugs carbamazepine and chlorpromazine and the compounds 7-nitroindazole and flavin semiquinone have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and pituitary, and related mouse phenotypes are renal/urinary system and homeostasis/metabolism.

Disease Ontology:8 A cognitive disorder that involves abnormal thinking and perceptions resulting in a disconnection with reality.

Wikipedia:65 Psychosis (from the Greek ???? psyche, \"mind/soul,\" and -???? -osis, \"abnormal condition or... more...

Aliases & Classifications for Psychotic Disorder

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Related Diseases for Psychotic Disorder

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Diseases related to Psychotic Disorder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 287)
idRelated DiseaseScoreTop Affiliating Genes
1schizoaffective disorder30.5NOS1, PRODH
2amyotrophic lateral sclerosis type 1430.2NOS1, MAOB
3huntington's disease30.1MAOB, NOS1
4schizophrenia30.1MAOB, PAH, NOS1, MOG, PRODH
5hepatic encephalopathy30.1NOS1, MAOB
6mood disorder30.0NOS1, MAOB
7alzheimer's disease29.8MAOB, CFI, NOS1
8dementia29.8NOS1, CFI, MAOB
9bipolar disorder29.8NOS1, PRODH, PAH, MAOB
10mental retardation29.7SHANK3, PAH, CFI
11parkinson's disease29.6NOS1, MAOB, PAH
12brain injury10.4
13traumatic brain injury10.4
14narcolepsy10.4
15major depressive disorder10.3
16melancholia10.2
17tardive dyskinesia10.2
18mental retardation, with or without nystagmus10.2
19endogenous depression10.2
20hepatitis10.2
21post-traumatic stress disorder10.2
22drug psychosis10.2
23hyperprolactinemia10.2
24alcohol dependence10.2
25schizophreniform disorder10.2
26acute orbital inflammation10.2
27delusional disorder10.2
28multiple system atrophy10.1
29transvestism10.1
30mental retardation, severe, with spasticity and tapetoretinal degeneration10.1
31nicotine dependence10.1
32alcohol-induced mental disorder10.1
33postpartum depression10.1
34narcissistic personality disorder10.1
35drug-induced mental disorder10.1
36physical disorder10.1
37attention deficit hyperactivity disorder10.1
38rett syndrome10.1
39conduct disorder10.1
40progressive supranuclear palsy10.1
41pedophilia10.1
42ego-dystonic sexual orientation10.1
43exhibitionism10.1
44neurotic disorder10.1
45trichotillomania10.1
46atypical autism10.1
47voyeurism10.1
48social phobia10.1
49anxiety disorder10.1
50dissociative disorder10.1

Graphical network of the top 20 diseases related to Psychotic Disorder:



Diseases related to psychotic disorder

Symptoms for Psychotic Disorder

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Genetic Tests for Psychotic Disorder

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Anatomical Context for Psychotic Disorder

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MalaCards organs/tissues related to Psychotic Disorder:

32
Brain, Heart, Pituitary, Bone, Testes, Temporal lobe

Animal Models for Psychotic Disorder or affiliated genes

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MGI Mouse Phenotypes related to Psychotic Disorder:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053677.9CFI, NOS1, MAOB, PAH
2MP:00053767.6NOS1, MAOB, PRODH, PAH, CFI
3MP:00053787.5MOG, PRODH, PAH, SHANK3, NOS1
4MP:00053867.3PRODH, NOS1, MOG, PAH, SHANK3, MAOB
5MP:00036317.3NOS1, MAOB, MOG, SHANK3, PRODH, PAH

Publications for Psychotic Disorder

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Articles related to Psychotic Disorder:

(show top 50)    (show all 267)
idTitleAuthorsYear
1
Neuropsychological effects of maintenance treatment with Clozapine in Treatment-Resistant Psychotic Disorder. (24715364)
2014
2
Intermediate phenotype analysis of patients, unaffected siblings, and healthy controls identifies VMAT2 as a candidate gene for psychotic disorder and neurocognition. (22532702)
2013
3
The prevalence of diabetes mellitus is increased in relatives of patients with a non-affective psychotic disorder. (23245702)
2013
4
Beliefs about health, health risks and health expectations from the perspective of people with a psychotic disorder. (24039643)
2013
5
Mortality and its determinants in people with psychotic disorder. (23257931)
2013
6
Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: implications for brain energy metabolism and neurotrophic signaling. (22018957)
2012
7
Psychotic disorder, hypertension and seizures associated with vitamin B12 deficiency: a case report. (22027500)
2012
8
Cognitive functioning and age at onset in non-affective psychotic disorder. (22582732)
2012
9
A case of diagnosing a long-standing psychotic disorder during medical withdrawal. (22494235)
2012
10
Pituitary volume, stress reactivity and genetic risk for psychotic disorder. (22130309)
2012
11
Psychotic disorder due to traumatic brain injury: analysis of case studies in the literature. (23037642)
2012
12
Mismanagement of Wilson's disease as psychotic disorder. (23326792)
2012
13
Wernicke's encephalopathy mimicking an acute psychotic disorder. (23224464)
2012
14
Reflections on Asperger syndrome and comorbidity with psychotic disorders. (21404153)
2011
15
Elevated bilirubin in acute and transient psychotic disorder. (20178091)
2010
16
The varying impact of type, timing and frequency of exposure to childhood adversity on its association with adult psychotic disorder. (20178679)
2010
17
Shared obsessive-compulsive disorder: broadening the concept of shared psychotic disorder. (20815674)
2010
18
Risperidone associated weight, leptin, and anthropometric changes in children and adolescents with psychotic disorders in early treatment. (20196182)
2010
19
Developing a risk-model of time to first-relapse for children and adolescents with a psychotic disorder. (19155804)
2009
20
Alcohol-induced psychotic disorder: a comparative study on the clinical characteristics of patients with alcohol dependence and schizophrenia. (19895763)
2009
21
Acute disseminated encephalomyelitis presenting as acute psychotic disorder. (19129570)
2008
22
Psychotic disorder and focal epilepsy in a left-handed patient with chromosome XYY abnormality. (19239080)
2008
23
Efficacy of atypical antipsychotics in early-onset schizophrenia and other psychotic disorders. (18533765)
2008
24
A cross-cultural study of employers' concerns about hiring people with psychotic disorder: implications for recovery. (17522747)
2007
25
Symptoms at first contact for psychotic disorder: comparison between native Dutch and ethnic minorities. (17669627)
2007
26
Psychotic disorder in a patient with central and extrapontine myelinolysis. (17472602)
2007
27
Shared psychotic disorder and mental retardation. (17667742)
2007
28
Psychotic disorder induced by oxybutynin: Presentation of two cases. (17163294)
2006
29
Revisiting cycloid psychosis: a case of an acute, transient and recurring psychotic disorder. (16442782)
2006
30
Transition rates from schizotypal disorder to psychotic disorder for first-contact patients included in the OPUS trial. A randomized clinical trial of integrated treatment and standard treatment. (16504481)
2006
31
Acute psychotic disorder after gastric bypass surgery: differential diagnosis and treatment. (16390883)
2006
32
A randomized controlled trial of a smoking cessation intervention among people with a psychotic disorder. (17074945)
2006
33
Klinefelter's syndrome (XXY) as a genetic model for psychotic disorders. (15729733)
2005
34
Hallucinatory experiences and onset of psychotic disorder: evidence that the risk is mediated by delusion formation. (15352927)
2004
35
Psychotic disorder and traumatic brain injury. (12773272)
2003
36
Ecstasy-induced psychotic disorder: six-month follow-up study. (12065963)
2002
37
Characteristics of psychotic disorder due to traumatic brain injury: an analysis of case studies in the literature. (11983787)
2002
38
An interferon-alpha-induced psychotic disorder in a patient with chronic hepatitis C. (11311181)
2001
39
Prevalence of psychotic disorder and community level of psychotic symptoms: an urban-rural comparison. (11448373)
2001
40
Treatment and 9-year outcome of butane-induced psychotic disorder in a butane-dependent Japanese male adolescent. (11285098)
2001
41
Risperidone versus haloperidol in acute and transient psychotic disorder. (21407958)
2000
42
Suicidality and substance misuse in first-admitted subjects with psychotic disorder. (10563457)
1999
43
Frontal lobe epilepsy presenting as a psychotic disorder with delusions and hallucinations: a case study. (18438324)
1999
44
Acute and transient psychotic disorder: comorbidity with personality disorder. (9021000)
1996
45
Psychotic disorder associated with isoniazid. (8961730)
1996
46
Implosive therapy as an adjunctive treatment in a psychotic disorder: a case report. (7593689)
1995
47
Psychotic disorder caused by a general medical condition, with delusions. Secondary "organic" delusional syndromes. (7659604)
1995
48
Shared psychotic disorder: a critical review of the literature. (8548718)
1995
49
The concept of cycloid psychotic disorder. (3050983)
1988
50
Use of the Proverbs Test for the identification of psychotic disorder. (5542466)
1971

Variations for Psychotic Disorder

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Expression for genes affiliated with Psychotic Disorder

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Expression patterns in normal tissues for genes affiliated with Psychotic Disorder

Search GEO for disease gene expression data for Psychotic Disorder.

Pathways for genes affiliated with Psychotic Disorder

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Pathways related to Psychotic Disorder according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
phenylalanine utilization37
noradrenaline and adrenaline degradation37
phenylalanine degradation IV37
9.1PAH, MAOB
29.1MAOB, PAH
3
Show member pathways
citrulline-nitric oxide cycle37
arginine degradation I (arginase pathway)37
proline degradation37
glutamine degradation I37
proline biosynthesis I37
superpathway of citrulline metabolism37
proline biosynthesis II (from arginine)37
citrulline biosynthesis37
arginine degradation VI (arginase 2 pathway)37
Urea cycle and metabolism of amino groups37
asparagine biosynthesis I37
4-hydroxyproline degradation I37
citrulline degradation37
8.9PRODH, MAOB, NOS1
4
Show member pathways
8.9SHANK3, MAOB, NOS1
5
Show member pathways
8.1NOS1, MAOB, PRODH, PAH

Compounds for genes affiliated with Psychotic Disorder

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Sources:
44Novoseek, 11DrugBank, 50PharmGKB, 28IUPHAR, 24HMDB
See all sources

Compounds related to Psychotic Disorder according to GeneCards/GeneDecks:

(show all 32)
idCompoundScoreTop Affiliating Genes
17-nitroindazole44 1110.7NOS1, MAOB
2flavin semiquinone449.7MAOB, NOS1
3flavin-adenine dinucleotide44 1110.7MAOB, NOS1
4flavin449.7MAOB, NOS1
5methamphetamine44 50 1111.6NOS1, MAOB
6fluoxetine44 50 28 1112.6MAOB, NOS1
7mptp449.6NOS1, MAOB
8imipramine44 28 50 24 1113.6NOS1, MAOB
9cocaine44 1110.4MAOB, NOS1
10dihydrobiopterin44 2410.4NOS1, PAH
11sepiapterin44 2410.4NOS1, PAH
125-hydroxytryptamine449.4MAOB, NOS1
13pterin44 2410.4PAH, NOS1
14tetrahydrobiopterin44 24 1111.4NOS1, PAH
15levodopa44 1110.4PAH, MAOB
16choline44 24 1111.3NOS1, MAOB
17amine449.3PAH, MAOB
18nicotine44 28 50 1112.3NOS1, MAOB
19catecholamine449.3PAH, MAOB
20FAD249.3NOS1, MAOB, PRODH
21creatinine449.1NOS1, MAOB, CFI
22carbon449.0NOS1, MAOB
23folate448.9MAOB, NOS1, PAH
24norepinephrine44 24 1110.8PAH, NOS1, MAOB
25glutamate448.8NOS1, MAOB, SHANK3, PRODH
26nitric oxide44 24 1110.8NOS1, MOG, PAH
27dopamine44 28 24 1111.8NOS1, MAOB, PAH
28h2o2448.8MAOB, NOS1, PAH
29oxygen44 249.5NOS1, PAH, MOG, MAOB
30Water248.5NOS1, PAH, PRODH, MAOB
31calcium44 50 24 1111.0PAH, CFI, NOS1, MOG
32serine448.0PAH, MAOB, NOS1, MOG, CFI

GO Terms for genes affiliated with Psychotic Disorder

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Biological processes related to Psychotic Disorder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neurotransmitter biosynthetic processGO:0421369.0NOS1, PAH

Molecular functions related to Psychotic Disorder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1scaffold protein bindingGO:0971109.3NOS1, SHANK3
2amino acid bindingGO:0165979.2PRODH, PAH
3flavin adenine dinucleotide bindingGO:0506609.0NOS1, MAOB
4iron ion bindingGO:0055069.0NOS1, PAH

Products for genes affiliated with Psychotic Disorder

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  • Antibodies
  • Proteins
  • Lysates

Sources for Psychotic Disorder

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet