MCID: PSY004
MIFTS: 53

Psychotic Disorder malady

Mental diseases, Neuronal diseases categories

Summaries for Psychotic Disorder

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MedlinePlus:32 Mental disorders include a wide range of problems, including anxiety disorders, including panic disorder, obsessive-compulsive disorder, post-traumatic stress disorder, and phobias bipolar disorder depression mood disorders personality disorders psychotic disorders, including schizophrenia there are many causes of mental disorders. your genes and family history may play a role. your life experiences, such as stress or a history of abuse, may also matter. biological factors can also be part of the cause. a traumatic brain injury can lead to a mental disorder. a mother's exposure to viruses or toxic chemicals while pregnant may play a part. other factors may increase your risk, such as use of illegal drugs or having a serious medical condition like cancer. medications and counseling can help many mental disorders.

MalaCards based summary: Psychotic Disorder, also known as psychotic disorders, is related to schizophrenia and hepatic encephalopathy. An important gene associated with Psychotic Disorder is MOG (myelin oligodendrocyte glycoprotein), and among its related pathways are Phenylalanine metabolism and Tyrosine metabolism p.1 dopamine . The drugs carbamazepine and chlorpromazine and the compounds 7-nitroindazole and flavin semiquinone have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and pituitary, and related mouse phenotypes are renal/urinary system and homeostasis/metabolism.

Disease Ontology:9 A cognitive disorder that involves abnormal thinking and perceptions resulting in a disconnection with reality.

Aliases & Classifications for Psychotic Disorder

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Related Diseases for Psychotic Disorder

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Graphical network of the top 20 diseases related to Psychotic Disorder:



Diseases related to psychotic disorder

Symptoms for Psychotic Disorder

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Genetic Tests for Psychotic Disorder

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Anatomical Context for Psychotic Disorder

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MalaCards organs/tissues related to Psychotic Disorder:

31
Brain, Heart, Pituitary, Eye, Bone, Small intestine, Testes, Temporal lobe

Animal Models for Psychotic Disorder or affiliated genes

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MGI Mouse Phenotypes related to Psychotic Disorder:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053677.9CFI, PAH, MAOB, NOS1
2MP:00053767.6NOS1, MAOB, PRODH, PAH, CFI
3MP:00053787.5SHANK3, PAH, PRODH, MOG, NOS1
4MP:00053867.3NOS1, MAOB, MOG, PRODH, PAH, SHANK3
5MP:00036317.3SHANK3, PAH, PRODH, MOG, MAOB, NOS1

Publications for Psychotic Disorder

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Articles related to Psychotic Disorder:

(show top 50)    (show all 282)
idTitleAuthorsYear
1
Neuropsychological effects of maintenance treatment with Clozapine in Treatment-Resistant Psychotic Disorder. (24715364)
2014
2
Intermediate phenotype analysis of patients, unaffected siblings, and healthy controls identifies VMAT2 as a candidate gene for psychotic disorder and neurocognition. (22532702)
2013
3
The prevalence of diabetes mellitus is increased in relatives of patients with a non-affective psychotic disorder. (23245702)
2013
4
Beliefs about health, health risks and health expectations from the perspective of people with a psychotic disorder. (24039643)
2013
5
Mortality and its determinants in people with psychotic disorder. (23257931)
2013
6
Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: implications for brain energy metabolism and neurotrophic signaling. (22018957)
2012
7
Psychotic disorder, hypertension and seizures associated with vitamin B12 deficiency: a case report. (22027500)
2012
8
Cognitive functioning and age at onset in non-affective psychotic disorder. (22582732)
2012
9
A case of diagnosing a long-standing psychotic disorder during medical withdrawal. (22494235)
2012
10
Pituitary volume, stress reactivity and genetic risk for psychotic disorder. (22130309)
2012
11
Psychotic disorder due to traumatic brain injury: analysis of case studies in the literature. (23037642)
2012
12
Mismanagement of Wilson's disease as psychotic disorder. (23326792)
2012
13
Wernicke's encephalopathy mimicking an acute psychotic disorder. (23224464)
2012
14
Reflections on Asperger syndrome and comorbidity with psychotic disorders. (21404153)
2011
15
Elevated bilirubin in acute and transient psychotic disorder. (20178091)
2010
16
The varying impact of type, timing and frequency of exposure to childhood adversity on its association with adult psychotic disorder. (20178679)
2010
17
Shared obsessive-compulsive disorder: broadening the concept of shared psychotic disorder. (20815674)
2010
18
Risperidone associated weight, leptin, and anthropometric changes in children and adolescents with psychotic disorders in early treatment. (20196182)
2010
19
Developing a risk-model of time to first-relapse for children and adolescents with a psychotic disorder. (19155804)
2009
20
Alcohol-induced psychotic disorder: a comparative study on the clinical characteristics of patients with alcohol dependence and schizophrenia. (19895763)
2009
21
Acute disseminated encephalomyelitis presenting as acute psychotic disorder. (19129570)
2008
22
Psychotic disorder and focal epilepsy in a left-handed patient with chromosome XYY abnormality. (19239080)
2008
23
Efficacy of atypical antipsychotics in early-onset schizophrenia and other psychotic disorders. (18533765)
2008
24
A cross-cultural study of employers' concerns about hiring people with psychotic disorder: implications for recovery. (17522747)
2007
25
Symptoms at first contact for psychotic disorder: comparison between native Dutch and ethnic minorities. (17669627)
2007
26
Psychotic disorder in a patient with central and extrapontine myelinolysis. (17472602)
2007
27
Shared psychotic disorder and mental retardation. (17667742)
2007
28
Psychotic disorder induced by oxybutynin: Presentation of two cases. (17163294)
2006
29
Revisiting cycloid psychosis: a case of an acute, transient and recurring psychotic disorder. (16442782)
2006
30
Transition rates from schizotypal disorder to psychotic disorder for first-contact patients included in the OPUS trial. A randomized clinical trial of integrated treatment and standard treatment. (16504481)
2006
31
Acute psychotic disorder after gastric bypass surgery: differential diagnosis and treatment. (16390883)
2006
32
A randomized controlled trial of a smoking cessation intervention among people with a psychotic disorder. (17074945)
2006
33
Klinefelter's syndrome (XXY) as a genetic model for psychotic disorders. (15729733)
2005
34
Hallucinatory experiences and onset of psychotic disorder: evidence that the risk is mediated by delusion formation. (15352927)
2004
35
Psychotic disorder and traumatic brain injury. (12773272)
2003
36
Ecstasy-induced psychotic disorder: six-month follow-up study. (12065963)
2002
37
Characteristics of psychotic disorder due to traumatic brain injury: an analysis of case studies in the literature. (11983787)
2002
38
An interferon-alpha-induced psychotic disorder in a patient with chronic hepatitis C. (11311181)
2001
39
Prevalence of psychotic disorder and community level of psychotic symptoms: an urban-rural comparison. (11448373)
2001
40
Treatment and 9-year outcome of butane-induced psychotic disorder in a butane-dependent Japanese male adolescent. (11285098)
2001
41
Risperidone versus haloperidol in acute and transient psychotic disorder. (21407958)
2000
42
Suicidality and substance misuse in first-admitted subjects with psychotic disorder. (10563457)
1999
43
Frontal lobe epilepsy presenting as a psychotic disorder with delusions and hallucinations: a case study. (18438324)
1999
44
Acute and transient psychotic disorder: comorbidity with personality disorder. (9021000)
1996
45
Psychotic disorder associated with isoniazid. (8961730)
1996
46
Implosive therapy as an adjunctive treatment in a psychotic disorder: a case report. (7593689)
1995
47
Psychotic disorder caused by a general medical condition, with delusions. Secondary "organic" delusional syndromes. (7659604)
1995
48
Shared psychotic disorder: a critical review of the literature. (8548718)
1995
49
The concept of cycloid psychotic disorder. (3050983)
1988
50
Use of the Proverbs Test for the identification of psychotic disorder. (5542466)
1971

Variations for Psychotic Disorder

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Expression for genes affiliated with Psychotic Disorder

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Search GEO for disease gene expression data for Psychotic Disorder.

Pathways for genes affiliated with Psychotic Disorder

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Pathways related to Psychotic Disorder according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
phenylalanine utilization36
noradrenaline and adrenaline degradation36
phenylalanine degradation IV36
9.1MAOB, PAH
29.1MAOB, PAH
3
Show member pathways
citrulline-nitric oxide cycle36
arginine degradation I (arginase pathway)36
proline degradation36
glutamine degradation I36
proline biosynthesis I36
superpathway of citrulline metabolism36
proline biosynthesis II (from arginine)36
citrulline biosynthesis36
arginine degradation VI (arginase 2 pathway)36
Urea cycle and metabolism of amino groups36
asparagine biosynthesis I36
4-hydroxyproline degradation I36
citrulline degradation36
8.9NOS1, MAOB, PRODH
4
Show member pathways
8.9SHANK3, MAOB, NOS1
5
Show member pathways
8.1NOS1, MAOB, PRODH, PAH

Compounds for genes affiliated with Psychotic Disorder

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Sources:
43Novoseek, 12DrugBank, 49PharmGKB, 28IUPHAR, 24HMDB
See all sources

Compounds related to Psychotic Disorder according to GeneCards Suite gene sharing:

(show all 32)
idCompoundScoreTop Affiliating Genes
17-nitroindazole43 1210.7NOS1, MAOB
2flavin semiquinone439.7NOS1, MAOB
3flavin-adenine dinucleotide43 1210.7NOS1, MAOB
4flavin439.7MAOB, NOS1
5methamphetamine43 49 1211.6NOS1, MAOB
6fluoxetine43 49 28 1212.6NOS1, MAOB
7mptp439.6NOS1, MAOB
8imipramine43 28 49 24 1213.6NOS1, MAOB
9cocaine43 1210.4NOS1, MAOB
10dihydrobiopterin43 2410.4NOS1, PAH
11sepiapterin43 2410.4NOS1, PAH
125-hydroxytryptamine439.4NOS1, MAOB
13pterin43 2410.4NOS1, PAH
14tetrahydrobiopterin43 24 1211.4NOS1, PAH
15levodopa43 1210.4MAOB, PAH
16choline43 24 1211.3MAOB, NOS1
17amine439.3PAH, MAOB
18nicotine43 28 49 1212.3NOS1, MAOB
19catecholamine439.3MAOB, PAH
20FAD249.3NOS1, MAOB, PRODH
21creatinine439.1CFI, MAOB, NOS1
22carbon439.0NOS1, MAOB
23folate438.9PAH, MAOB, NOS1
24norepinephrine43 24 1210.8PAH, MAOB, NOS1
25glutamate438.8SHANK3, PRODH, MAOB, NOS1
26nitric oxide43 24 1210.8PAH, MOG, NOS1
27dopamine43 28 24 1211.8PAH, MAOB, NOS1
28h2o2438.8NOS1, MAOB, PAH
29oxygen43 249.5PAH, MOG, MAOB, NOS1
30Water248.5PAH, PRODH, MAOB, NOS1
31calcium43 49 24 1211.0NOS1, MOG, PAH, CFI
32serine438.0CFI, PAH, MOG, MAOB, NOS1

GO Terms for genes affiliated with Psychotic Disorder

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Biological processes related to Psychotic Disorder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1neurotransmitter biosynthetic processGO:00421369.0NOS1, PAH

Molecular functions related to Psychotic Disorder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1scaffold protein bindingGO:00971109.3NOS1, SHANK3
2amino acid bindingGO:00165979.2PRODH, PAH
3flavin adenine dinucleotide bindingGO:00506609.0NOS1, MAOB
4iron ion bindingGO:00055069.0NOS1, PAH

Products for genes affiliated with Psychotic Disorder

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Psychotic Disorder

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet