MCID: PSY004
MIFTS: 60

Psychotic Disorder malady

Mental diseases, Neuronal diseases categories
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Summaries for Psychotic Disorder

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Sources:
8Disease Ontology, 34MedlinePlus, 65Wikipedia, 33MalaCards
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Fully expand this MalaCard
MedlinePlus:34 Mental disorders include a wide range of problems, including anxiety disorders, including panic disorder, obsessive-compulsive disorder, post-traumatic stress disorder, and phobias bipolar disorder depression mood disorders personality disorders psychotic disorders, including schizophrenia there are many causes of mental disorders. your genes and family history may play a role. your life experiences, such as stress or a history of abuse, may also matter. biological factors can also be part of the cause. a traumatic brain injury can lead to a mental disorder. a mother's exposure to viruses or toxic chemicals while pregnant may play a part. other factors may increase your risk, such as use of illegal drugs or having a serious medical condition like cancer. medications and counseling can help many mental disorders.

MalaCards: Psychotic Disorder, also known as psychotic disorders, is related to schizophrenia and schizoaffective disorder. An important gene associated with Psychotic Disorder is MOG (myelin oligodendrocyte glycoprotein), and among its related pathways are Phenylalanine metabolism and Tyrosine metabolism p.1 dopamine . The drugs carbamazepine and chlorpromazine and the compounds 7-nitroindazole and flavin semiquinone have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and pituitary, and related mouse phenotypes are renal/urinary system and homeostasis/metabolism.

Disease Ontology:8 A cognitive disorder that involves abnormal thinking and perceptions resulting in a disconnection with reality.

Wikipedia:65 Psychosis (from the Greek ???? psyche, \"mind/soul\", and -???? -osis, \"abnormal condition or... more...

Aliases & Classifications for Psychotic Disorder

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Sources:
8Disease Ontology, 45Novoseek, 34MedlinePlus, 62UMLS, 27ICD9CM, 25ICD10
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Related Diseases for Psychotic Disorder

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Psychotic Disorder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 275)
idRelated DiseaseScoreTop Affiliating Genes
1schizophrenia30.8MAOB, PAH, NOS1, MOG, PRODH
2schizoaffective disorder30.4NOS1, PRODH
3amyotrophic lateral sclerosis30.2NOS1, MAOB
4bipolar disorder30.2NOS1, PRODH, PAH, MAOB
5huntington's disease30.1MAOB, NOS1
6alzheimer's disease30.1MAOB, CFI, NOS1
7hepatic encephalopathy30.0NOS1, MAOB
8mood disorder30.0NOS1, MAOB
9parkinson's disease30.0NOS1, MAOB, PAH
10dementia29.9NOS1, CFI, MAOB
11mental retardation29.9SHANK3, PAH, CFI
12intellectual disability29.8PAH, SHANK3
13brain injury10.4
14traumatic brain injury10.4
15narcolepsy10.4
16major depressive disorder10.3
17melancholia10.3
18mental retardation, with or without nystagmus10.2
19endogenous depression10.2
20tardive dyskinesia10.2
21drug psychosis10.1
22post-traumatic stress disorder10.1
23schizophreniform disorder10.1
24hyperprolactinemia10.1
25alcohol dependence10.1
26acute orbital inflammation10.1
27delusional disorder10.1
28transvestism10.1
29multiple system atrophy10.1
30mental retardation, severe, with spasticity and tapetoretinal degeneration10.1
31postpartum depression10.1
32narcissistic personality disorder10.0
33nicotine dependence10.0
34alcohol-induced mental disorder10.0
35drug-induced mental disorder10.0
36physical disorder10.0
37atypical autism10.0
38rett syndrome10.0
39conduct disorder10.0
40voyeurism10.0
41progressive supranuclear palsy10.0
42exhibitionism10.0
43neurotic disorder10.0
44trichotillomania10.0
45pedophilia10.0
46ego-dystonic sexual orientation10.0
47anxiety disorder10.0
48dissociative disorder10.0
49eating disorder10.0
50fetishism10.0

Graphical network of the top 20 diseases related to Psychotic Disorder:



Diseases related to psychotic disorder

Symptoms for Psychotic Disorder

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Genetic Tests for Psychotic Disorder

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Anatomical Context for Psychotic Disorder

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Sources:
33MalaCards
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MalaCards organs/tissues related to Psychotic Disorder:

33
Brain, Heart, Pituitary, Bone, Testes, Temporal lobe

Animal Models for Psychotic Disorder or affiliated genes

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Sources:
37MGI
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MGI Mouse Phenotypes related to Psychotic Disorder:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053677.9CFI, NOS1, MAOB, PAH
2MP:00053767.6NOS1, MAOB, PRODH, PAH, CFI
3MP:00053787.5MOG, PRODH, PAH, SHANK3, NOS1
4MP:00053867.3PRODH, NOS1, MOG, PAH, SHANK3, MAOB
5MP:00036317.3NOS1, MAOB, MOG, SHANK3, PRODH, PAH

Publications for Psychotic Disorder

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Sources:
52PubMed
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Articles related to Psychotic Disorder:

(show top 50)    (show all 243)
idTitleAuthorsYear
1
Intermediate phenotype analysis of patients, unaffected siblings, and healthy controls identifies VMAT2 as a candidate gene for psychotic disorder and neurocognition. (22532702)
2013
2
The prevalence of diabetes mellitus is increased in relatives of patients with a non-affective psychotic disorder. (23245702)
2013
3
Beliefs about health, health risks and health expectations from the perspective of people with a psychotic disorder. (24039643)
2013
4
Mortality and its determinants in people with psychotic disorder. (23257931)
2013
5
Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: implications for brain energy metabolism and neurotrophic signaling. (22018957)
2012
6
Psychotic disorder, hypertension and seizures associated with vitamin B12 deficiency: a case report. (22027500)
2012
7
Cognitive functioning and age at onset in non-affective psychotic disorder. (22582732)
2012
8
A case of diagnosing a long-standing psychotic disorder during medical withdrawal. (22494235)
2012
9
Pituitary volume, stress reactivity and genetic risk for psychotic disorder. (22130309)
2012
10
Psychotic disorder due to traumatic brain injury: analysis of case studies in the literature. (23037642)
2012
11
Mismanagement of Wilson's disease as psychotic disorder. (23326792)
2012
12
Wernicke's encephalopathy mimicking an acute psychotic disorder. (23224464)
2012
13
Reflections on Asperger syndrome and comorbidity with psychotic disorders. (21404153)
2011
14
Elevated bilirubin in acute and transient psychotic disorder. (20178091)
2010
15
The varying impact of type, timing and frequency of exposure to childhood adversity on its association with adult psychotic disorder. (20178679)
2010
16
Shared obsessive-compulsive disorder: broadening the concept of shared psychotic disorder. (20815674)
2010
17
Risperidone associated weight, leptin, and anthropometric changes in children and adolescents with psychotic disorders in early treatment. (20196182)
2010
18
Developing a risk-model of time to first-relapse for children and adolescents with a psychotic disorder. (19155804)
2009
19
Alcohol-induced psychotic disorder: a comparative study on the clinical characteristics of patients with alcohol dependence and schizophrenia. (19895763)
2009
20
Acute disseminated encephalomyelitis presenting as acute psychotic disorder. (19129570)
2008
21
Psychotic disorder and focal epilepsy in a left-handed patient with chromosome XYY abnormality. (19239080)
2008
22
Efficacy of atypical antipsychotics in early-onset schizophrenia and other psychotic disorders. (18533765)
2008
23
A cross-cultural study of employers' concerns about hiring people with psychotic disorder: implications for recovery. (17522747)
2007
24
Symptoms at first contact for psychotic disorder: comparison between native Dutch and ethnic minorities. (17669627)
2007
25
Psychotic disorder in a patient with central and extrapontine myelinolysis. (17472602)
2007
26
Shared psychotic disorder and mental retardation. (17667742)
2007
27
Psychotic disorder induced by oxybutynin: Presentation of two cases. (17163294)
2006
28
Revisiting cycloid psychosis: a case of an acute, transient and recurring psychotic disorder. (16442782)
2006
29
Transition rates from schizotypal disorder to psychotic disorder for first-contact patients included in the OPUS trial. A randomized clinical trial of integrated treatment and standard treatment. (16504481)
2006
30
Acute psychotic disorder after gastric bypass surgery: differential diagnosis and treatment. (16390883)
2006
31
A randomized controlled trial of a smoking cessation intervention among people with a psychotic disorder. (17074945)
2006
32
Klinefelter's syndrome (XXY) as a genetic model for psychotic disorders. (15729733)
2005
33
Hallucinatory experiences and onset of psychotic disorder: evidence that the risk is mediated by delusion formation. (15352927)
2004
34
Psychotic disorder and traumatic brain injury. (12773272)
2003
35
Ecstasy-induced psychotic disorder: six-month follow-up study. (12065963)
2002
36
Characteristics of psychotic disorder due to traumatic brain injury: an analysis of case studies in the literature. (11983787)
2002
37
Prevalence of psychotic disorder and community level of psychotic symptoms: an urban-rural comparison. (11448373)
2001
38
Treatment and 9-year outcome of butane-induced psychotic disorder in a butane-dependent Japanese male adolescent. (11285098)
2001
39
Changes in insurance coverage and extent of care during the two years after first hospitalization for a psychotic disorder. (11141534)
2001
40
Risperidone versus haloperidol in acute and transient psychotic disorder. (21407958)
2000
41
Suicidality and substance misuse in first-admitted subjects with psychotic disorder. (10563457)
1999
42
Frontal lobe epilepsy presenting as a psychotic disorder with delusions and hallucinations: a case study. (18438324)
1999
43
Substance use among patients with a psychotic disorder in a psychiatric emergency room. (9057237)
1997
44
Acute and transient psychotic disorder: comorbidity with personality disorder. (9021000)
1996
45
Psychotic disorder associated with isoniazid. (8961730)
1996
46
Implosive therapy as an adjunctive treatment in a psychotic disorder: a case report. (7593689)
1995
47
Psychotic disorder caused by a general medical condition, with delusions. Secondary "organic" delusional syndromes. (7659604)
1995
48
Shared psychotic disorder: a critical review of the literature. (8548718)
1995
49
The concept of cycloid psychotic disorder. (3050983)
1988
50
Use of the Proverbs Test for the identification of psychotic disorder. (5542466)
1971

Variations for Psychotic Disorder

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Expression for genes affiliated with Psychotic Disorder

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Psychotic Disorder

Search GEO for disease gene expression data for Psychotic Disorder.

Pathways for genes affiliated with Psychotic Disorder

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Sources:
50PathCards, 30KEGG, 38NCBI BioSystems Database, 60Thomson Reuters, 55Reactome
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Pathways related to Psychotic Disorder according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
phenylalanine utilization38
noradrenaline and adrenaline degradation38
phenylalanine degradation IV38
9.1PAH, MAOB
29.1MAOB, PAH
3
Show member pathways
citrulline-nitric oxide cycle38
arginine degradation I (arginase pathway)38
proline degradation38
glutamine degradation I38
proline biosynthesis I38
superpathway of citrulline metabolism38
proline biosynthesis II (from arginine)38
citrulline biosynthesis38
arginine degradation VI (arginase 2 pathway)38
Urea cycle and metabolism of amino groups38
asparagine biosynthesis I38
4-hydroxyproline degradation I38
citrulline degradation38
8.9PRODH, MAOB, NOS1
4
Show member pathways
8.9SHANK3, MAOB, NOS1
5
Show member pathways
8.1NOS1, MAOB, PRODH, PAH

Compounds for genes affiliated with Psychotic Disorder

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Sources:
45Novoseek, 11DrugBank, 51PharmGKB, 29IUPHAR, 24HMDB
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Compounds related to Psychotic Disorder according to GeneCards/GeneDecks:

(show all 32)
idCompoundScoreTop Affiliating Genes
17-nitroindazole45 1110.7NOS1, MAOB
2flavin semiquinone459.7MAOB, NOS1
3flavin-adenine dinucleotide45 1110.7MAOB, NOS1
4flavin459.7MAOB, NOS1
5methamphetamine45 51 1111.6NOS1, MAOB
6fluoxetine45 51 29 1112.6MAOB, NOS1
7mptp459.6NOS1, MAOB
8imipramine45 29 51 24 1113.6NOS1, MAOB
9cocaine45 1110.4MAOB, NOS1
10dihydrobiopterin45 2410.4NOS1, PAH
11sepiapterin45 2410.4NOS1, PAH
125-hydroxytryptamine459.4MAOB, NOS1
13pterin45 2410.4PAH, NOS1
14tetrahydrobiopterin45 24 1111.4NOS1, PAH
15levodopa45 1110.4PAH, MAOB
16choline45 24 1111.3NOS1, MAOB
17amine459.3PAH, MAOB
18nicotine45 29 51 1112.3NOS1, MAOB
19catecholamine459.3PAH, MAOB
20FAD249.3NOS1, MAOB, PRODH
21creatinine459.1NOS1, MAOB, CFI
22carbon459.0NOS1, MAOB
23folate458.9MAOB, NOS1, PAH
24norepinephrine45 24 1110.8PAH, NOS1, MAOB
25glutamate458.8NOS1, MAOB, SHANK3, PRODH
26nitric oxide45 24 1110.8NOS1, MOG, PAH
27dopamine45 29 24 1111.8NOS1, MAOB, PAH
28h2o2458.8MAOB, NOS1, PAH
29oxygen45 249.5NOS1, PAH, MOG, MAOB
30Water248.5NOS1, PAH, PRODH, MAOB
31calcium45 51 24 1111.0PAH, CFI, NOS1, MOG
32serine458.0PAH, MAOB, NOS1, MOG, CFI

GO Terms for genes affiliated with Psychotic Disorder

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16Gene Ontology
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Biological processes related to Psychotic Disorder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neurotransmitter biosynthetic processGO:0421369.0NOS1, PAH

Molecular functions related to Psychotic Disorder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1scaffold protein bindingGO:0971109.3NOS1, SHANK3
2amino acid bindingGO:0165979.2PRODH, PAH
3flavin adenine dinucleotide bindingGO:0506609.0NOS1, MAOB
4iron ion bindingGO:0055069.0NOS1, PAH

Products for genes affiliated with Psychotic Disorder

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Psychotic Disorder

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet