MCID: PTH001
MIFTS: 20

Pthirus Pubis Infestation

Categories: Infectious diseases

Aliases & Classifications for Pthirus Pubis Infestation

MalaCards integrated aliases for Pthirus Pubis Infestation:

Name: Pthirus Pubis Infestation 12 14
Infestation by Phthirus Pubis 12 69
Phthirus/pediculus Pubis - Pubic Lice - Crabs 12
Phthirus Pubis [pubic Louse] 12
Pediculosis Pubis 12
Phthiriasis Pubis 12
Pediculus Pubis 12
Phthirus Pubis 12
Crabs 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13760
ICD10 32 B85.3
ICD9CM 34 132.2
NCIt 46 C35777
UMLS 69 C0030759

Summaries for Pthirus Pubis Infestation

Disease Ontology : 12 A lice infestation that involves parasitic infestation by pubic lice Pthirus pubis, which are found in the pubic hair, less commonly in eyebrows, eyelashes, beard, mustache, armpit, perianal area, groin, trunk and scalp. The symptoms include itching in the pubic and groin area. Intense itching leads to scratching which can cause sores and secondary bacterial infection of the skin.

MalaCards based summary : Pthirus Pubis Infestation, also known as infestation by phthirus pubis, is related to green mud crab allergy and late yaws. An important gene associated with Pthirus Pubis Infestation is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I). The drugs Daratumumab and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include skin, and related phenotype is Increased mitotic index.

Related Diseases for Pthirus Pubis Infestation

Graphical network of the top 20 diseases related to Pthirus Pubis Infestation:



Diseases related to Pthirus Pubis Infestation

Symptoms & Phenotypes for Pthirus Pubis Infestation

GenomeRNAi Phenotypes related to Pthirus Pubis Infestation according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased mitotic index GR00110-A-0 8.62 MAPK13 TMPRSS15

Drugs & Therapeutics for Pthirus Pubis Infestation

Drugs for Pthirus Pubis Infestation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 69)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Daratumumab Approved Phase 3 945721-28-8
2 Antibodies Phase 3
3 Antibodies, Monoclonal Phase 3
4 Immunoglobulins Phase 3
5
Bevacizumab Approved, Investigational Phase 2,Phase 1 216974-75-3
6
Capecitabine Approved, Investigational Phase 2 154361-50-9 60953
7
Iron Approved Phase 1, Phase 2 7439-89-6 23925
8
Irinotecan Approved, Investigational Phase 1, Phase 2 97682-44-5, 100286-90-6 60838
9
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
10
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
11
Lenalidomide Approved Phase 2 191732-72-6 216326
12
Camptothecin Experimental Phase 1, Phase 2 7689-03-4
13 Angiogenesis Inhibitors Phase 2,Phase 1
14 Angiogenesis Modulating Agents Phase 2,Phase 1
15 Antimetabolites Phase 2,Not Applicable
16 Antimetabolites, Antineoplastic Phase 2
17 Micronutrients Phase 1, Phase 2
18 Trace Elements Phase 1, Phase 2
19 Anti-Bacterial Agents Phase 2,Phase 1
20 Anti-Infective Agents Phase 2,Phase 1
21 Immunosuppressive Agents Phase 2,Phase 1
22 Antineoplastic Agents, Phytogenic Phase 1, Phase 2
23 topoisomerase I inhibitors Phase 1, Phase 2
24 Topoisomerase Inhibitors Phase 1, Phase 2
25 Alkylating Agents Phase 2
26 Antiemetics Phase 2
27 Anti-Inflammatory Agents Phase 2,Not Applicable
28 Antineoplastic Agents, Hormonal Phase 2
29 Antirheumatic Agents Phase 2
30 Autonomic Agents Phase 2
31 BB 1101 Phase 2
32 Dexamethasone acetate Phase 2 1177-87-3
33 Gastrointestinal Agents Phase 2
34 glucocorticoids Phase 2
35 HIV Protease Inhibitors Phase 2
36 Hormone Antagonists Phase 2
37 Hormones Phase 2
38 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
39 Peripheral Nervous System Agents Phase 2
40
protease inhibitors Phase 2
41
Carboplatin Approved Phase 1 41575-94-4 10339178 38904 498142
42
Everolimus Approved Phase 1 159351-69-6 6442177
43
Miconazole Approved, Investigational, Vet_approved Phase 1 22916-47-8 4189
44
Pemetrexed Approved, Investigational Phase 1 150399-23-8, 137281-23-3 60843 446556
45
Sirolimus Approved, Investigational Phase 1 53123-88-9 46835353 6436030 5284616
46
Folic Acid Approved, Nutraceutical, Vet_approved Phase 1 59-30-3 6037
47
leucovorin Approved, Nutraceutical Phase 1 58-05-9 143 6006
48 Antibiotics, Antitubercular Phase 1
49 Antifungal Agents Phase 1
50 Folic Acid Antagonists Phase 1

Interventional clinical trials:

(show all 18)

# Name Status NCT ID Phase Drugs
1 Pom-dex Versus Pom-Cyclo-dex in MM Patients With Biochemical or Clinical Relapse, During Lena Maintenance Treatment Recruiting NCT03440411 Phase 3 Pomalidomide;Cyclophosphamide;Dexamethasone
2 A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma Recruiting NCT03301220 Phase 3 Daratumumab SC: daratumumab + rHuPH20
3 Preoperative Radiotherapy With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer: CRAB Phase II Study Unknown status NCT00842686 Phase 2 bevacizumab, capecitabine
4 Effect of Ejiao Compound in the Treatment of Postpartum Anemia of Qi-blood Deficiency Syndrome Unknown status NCT02656225 Phase 1, Phase 2 Ejiao compound;Niferex
5 Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients Recruiting NCT01941316 Phase 1, Phase 2 Carfilzomib;Irinotecan
6 Cyclophosphamide With Biochemical Progression During Lenalidomide-Dexamethasone Treatment for Relapsed/Refractory Multiple Myeloma (MM) Active, not recruiting NCT02206503 Phase 2 Cyclophosphamide;Lenalidomide;Dexamethasone
7 Study of Everolimus, Pemetrexed, Carboplatin, and Bevacizumab to Treat Stage IV Lung Cancer Completed NCT01700400 Phase 1 Everolimus;Pemetrexed;Carboplatin;Bevacizumab
8 Randomized Double-Blind Placebo-Controlled Crab or Shrimp Allergy Reduction Study Using Nambudripad Allergy Elimination Techniques Unknown status NCT02208414 Not Applicable
9 Impact of Plasma Levels of Colistin in Patients With Carbapenem Resistant Acinetobacter Baumannii Infection Unknown status NCT02482961 colistimethate sodium
10 Crabmeat and Health Study Completed NCT03104530
11 "Association Splitting" in Obsessive-Compulsive Disorder (OCD) Completed NCT01035242 Not Applicable
12 Correlation Between Estimated Right Atrial Pressure and BNP in Pulmonary HTN (CRAB-PH) Recruiting NCT02873039
13 Pilot Study on Traditional Chinese Medicine and Food Allergy Recruiting NCT02490813 Not Applicable
14 European Prospective Cohort Study on Enterobacteriaceae Showing Resistance to Carbapenems Recruiting NCT02709408
15 Project Survival-Prospective Biomarker Discovery Recruiting NCT02781012
16 Real-world Use of Carfilzomib Among Patients With Relapsed MM in Europe Recruiting NCT03091127
17 High Dose Therapy Followed by Autologous Transplantation for Myeloma Patients With Severe Renal Impairment Not yet recruiting NCT03234335
18 Treatment of Mild to Moderate Peri-implantitis Using an Oscillating Chitosan Device Not yet recruiting NCT03373448 Not Applicable

Search NIH Clinical Center for Pthirus Pubis Infestation

Genetic Tests for Pthirus Pubis Infestation

Anatomical Context for Pthirus Pubis Infestation

MalaCards organs/tissues related to Pthirus Pubis Infestation:

38
Skin

Publications for Pthirus Pubis Infestation

Articles related to Pthirus Pubis Infestation:

# Title Authors Year
1
The treatment of Pthirus pubis infestation of the eyelashes. ( 3322357 )
1987

Variations for Pthirus Pubis Infestation

Expression for Pthirus Pubis Infestation

Search GEO for disease gene expression data for Pthirus Pubis Infestation.

Pathways for Pthirus Pubis Infestation

GO Terms for Pthirus Pubis Infestation

Sources for Pthirus Pubis Infestation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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