MCID: PLM032
MIFTS: 49

Pulmonary Blastoma malady

Categories: Respiratory diseases, Rare diseases, Cancer diseases

Aliases & Classifications for Pulmonary Blastoma

About this section
Sources:
11Disease Ontology, 13DISEASES, 52Orphanet, 48Novoseek, 37MeSH, 66UMLS, 43NCIt, 38MESH via Orphanet, 29ICD10 via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Pulmonary Blastoma:

Name: Pulmonary Blastoma 11 13 52 48 37 66
Blastoma of Lung 11
 
Pneumoblastoma 52

Characteristics:

Orphanet epidemiological data:

52
pulmonary blastoma:
Inheritance: Multigenic/multifactorial; Age of onset: Adult; Age of death: adult

Classifications:



External Ids:

Disease Ontology11 DOID:4765
MeSH37 D018202
NCIt43 C3732
Orphanet52 ORPHA64741
SNOMED-CT60 189815007, 43149009
MESH via Orphanet38 D018202
ICD10 via Orphanet29 C34.1, C34.8, C34.9 C34.2, C34.3, more
UMLS via Orphanet67 C0206629

Summaries for Pulmonary Blastoma

About this section
Disease Ontology:11 An embryoma and malignant neoplasm of lung that derives from tissues of the lung and derives from pleura (a thin layer of tissue that covers the lungs and lines the interior wall of the chest cavity). it is most commonly effects children.

MalaCards based summary: Pulmonary Blastoma, also known as blastoma of lung, is related to epithelial predominant pulmonary blastoma and classic pulmonary blastoma, and has symptoms including hemoptysis, neoplasm of the lung and chest pain. An important gene associated with Pulmonary Blastoma is DICER1 (Dicer 1, Ribonuclease III), and among its related pathways are Thyroid cancer and Gastric cancer network 2. Affiliated tissues include lung, brain and fetal lung, and related mouse phenotypes are respiratory system and neoplasm.

Related Diseases for Pulmonary Blastoma

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Diseases related to Pulmonary Blastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 214)
idRelated DiseaseScoreTop Affiliating Genes
1epithelial predominant pulmonary blastoma34.0DICER1, SYP
2classic pulmonary blastoma29.5CHGA, DES, DICER1, EGFR, KRAS, NKX2-1
3pleuropulmonary blastoma11.8
4blastoma10.9
5spontaneous tension pneumothorax10.6DICER1, SYP
6vulvar benign neoplasm10.6SYP, TP53
7hypersensitivity reaction type ii disease10.6SYP, TP53
8goiter, multinodular 1, with or without sertoli-leydig cell tumors10.6DICER1, TP53
9brainstem intraparenchymal clear cell meningioma10.6SYP, TP53
10atypical choroid plexus papilloma10.6SYP, TP53
11sm-ahnmd10.6SYP, TP53
12vulva fibroepithelial polyp10.6SYP, TP53
13plexopathy10.6SYP, TP53
14malignant pineal area germ cell neoplasm10.6SYP, TP53
15peptic ulcer disease10.6EGFR, TP53
16tamoxifen-related endometrial lesion10.5EGFR, TP53
17pulmonary plasma cell granuloma10.5SYP, TP53
18animal phobia10.5EGFR, TP53
19immune system organ benign neoplasm10.5SYP, TP53
20cerebellum cancer10.5EGFR, TP53
21benign mastocytoma10.5SYP, TP53
22spinal cord glioma10.5SYP, TP53
23l-cell glucagon-like peptide producing tumor10.5SYP, TP53
24uterine corpus epithelioid leiomyosarcoma10.5EGFR, TP53
25herpes simplex10.5EGFR, TP53
26dysembryoplastic neuroepithelial tumor10.5DES, DICER1
27peritoneal benign neoplasm10.5SYP, TP53
28stampe sorensen syndrome10.5EGFR, TP53
29frontal sinus inverted papilloma10.5CHGA, TP53
30ovarian small cell carcinoma10.5EGFR, TP53
31ovary mixed epithelial carcinoma10.5CHGA, SYP
32esophagus small cell carcinoma10.5CHGA, SYP
33lice infestation10.5CHGA, SYP
34early myoclonic encephalopathy10.5EGFR, TP53
35central nervous system germinoma10.4CHGA, TP53
36pediatric ependymoma10.4SYP, TP53
37childhood malignant schwannoma10.4CHGA, SYP
38microglandular adenosis of breast10.4CHGA, SYP
39clear cell adenoma10.4CHGA, SYP
40focal facial dermal dysplasia10.4CHGA, SYP
41osteoblastoma10.4CHGA, SYP
42esophagus adenocarcinoma10.4CHGA, SYP
43fraxf syndrome10.4CHGA, SYP
44froelich syndrome10.4CHGA, SYP
45mature b-cell neoplasm10.4EGFR, TP53
46cervical benign neoplasm10.4EGFR, TP53
47lumbar plexus neoplasm10.4CHGA, SYP
48cutaneous mastocytosis10.4CHGA, SYP
49pancreatic serous cystic neoplasm10.4CHGA, SYP
50pilocytic astrocytoma10.4CHGA, SYP

Graphical network of the top 20 diseases related to Pulmonary Blastoma:



Diseases related to pulmonary blastoma

Symptoms for Pulmonary Blastoma

About this section

Symptoms:

 52 (show all 9)
  • weight loss
  • fever
  • dyspnea
  • hemoptysis
  • pulmonary infiltrates
  • recurrent pneumonia
  • cough
  • pleuropulmonary blastoma
  • chest pain

HPO human phenotypes related to Pulmonary Blastoma:

(show all 8)
id Description Frequency HPO Source Accession
1 hemoptysis hallmark (90%) HP:0002105
2 neoplasm of the lung hallmark (90%) HP:0100526
3 chest pain hallmark (90%) HP:0100749
4 weight loss typical (50%) HP:0001824
5 respiratory insufficiency typical (50%) HP:0002093
6 recurrent respiratory infections typical (50%) HP:0002205
7 abnormality of temperature regulation typical (50%) HP:0004370
8 abnormality of the pleura occasional (7.5%) HP:0002103

UMLS symptoms related to Pulmonary Blastoma:


coughing, dyspnea, hemoptysis

Drugs & Therapeutics for Pulmonary Blastoma

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Drugs for Pulmonary Blastoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
trastuzumabPhase 2751180288-69-19903
Synonyms:
180288-69-1
Anti HER2
Anti-erbB2 Monoclonal Antibody
D03257
HER2 Monoclonal Antibody
Herceptin
 
Herceptin (TN)
Ig gamma-1 chain C region
Trastuzumab
Trastuzumab (INN)
Trastuzumab (genetical recombination)
Trastuzumab (genetical recombination) (JAN)
trastuzumab
2
DoxilApproved June 1999167631703
Synonyms:
Dox-SL
Doxil
 
Evacet
LipoDox
Pegylated Liposomal Doxorubicin Hydrochloride
liposomal doxorubicin
3Isophosphamide mustard386
4
Mechlorethamine36351-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
 
KBioGR_001448
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
╬▓,╬▓'-dichlorodiethyl-N-methylamine
5
Vincristine8882068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
6
Ifosfamide3863778-73-23690
Synonyms:
(+-)-Ifosfamid
(+-)-Ifosphamide
(+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
(D,L)-Ifosfamide
(R,S)-Ifosphamide
(R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd
2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI)
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
3,} 2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
36341-88-5
3778-73-2
84711-20-6
A 4942
AB00513932
AC-2113
AC1L1GHW
ASTA Z 4942
Ambap3778-73-2
Asta Z 4942
BPBio1_000865
BRN 0611835
BSPBio_000785
C07047
CAS-3778-73-2
CCRIS 352
CHEBI:5864
CHEMBL1024
CID3690
Cyfos
D00343
D007069
DB01181
EINECS 223-237-3
HMS1570H07
HMS2090M12
HMS2093N07
HSDB 7023
Holoxan
Holoxan 1000
I-Phosphamide
I06-0494
IFEX (TN)
Ifex
Ifosfamid
Ifosfamida
Ifosfamida [INN-Spanish]
Ifosfamide (JAN/USP/INN)
 
Ifosfamide Sterile
Ifosfamide [USAN:INN:BAN:JAN]
Ifosfamidum
Ifosfamidum [INN-Latin]
Ifosphamide
Ifsofamide
Iphosphamid
Iphosphamid(e)
Iphosphamide
Iso Endoxan
Iso-Endoxan
Isoendoxan
Isofosfamide
Isophosphamide
Isosfamide
LS-102
LS-99799
MJF 9325
MJF-9325
MLS002154021
Mitoxana
Mitoxana, Ifex, Ifosfamide
MolPort-003-666-704
N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide
N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine
NCGC00016639-01
NCGC00179435-01
NCI-C01638
NCI60_000233
NPFAPI-04
NSC 109,724
NSC 109724
NSC-109,724
NSC-109724
NSC109,724
NSC109724
Naxamide
Prestwick0_000833
Prestwick1_000833
Prestwick2_000833
Prestwick3_000833
S1302_Selleck
SMR001233348
SPBio_002706
STL058690
UNII-UM20QQM95Y
WLN: T6NPOTJ AM2G BO B2G
Z 4942
Z-4942
Z4942
ifosfamide
isosfamide
{3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,
7
Doxorubicin167623214-92-831703
Synonyms:
(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(8S-cis)-10-((3-amino-2,3,6-Trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
111266-55-8
14-Hydroxydaunomycin
14-Hydroxydaunorubicine
14-hydroxydaunomycin
14-hydroxydaunorubicine
23214-92-8
23257-17-2
24385-08-8
25311-50-6
25316-40-9
25316-40-9 (hydrochloride)
29042-30-6
AC1L1M5T
AC1Q29OJ
ADM
ADR
Adriablastin
Adriacin (hydrochloride salt)
Adriamycin
Adriamycin PFS
Adriamycin PFS (hydrochloride salt)
Adriamycin RDF
Adriamycin RDF (hydrochloride salt)
Adriamycin Semiquinone
Adriamycin semiquinone
Adriblas tina
Adriblastin
Adriblastina
Adriblastina (TN)
Adriblastina (hydrochloride salt)
Aerosolized Doxorubicin
BPBio1_000502
BRD-K92093830-003-04-3
BSPBio_000456
BSPBio_001031
C01661
C27H29NO11
CCRIS 739
CHEBI:28748
CHEMBL179
CID31703
Caelyx
Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74
Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120
D03899
DB00997
DM2
DOX-SL
Doxil
Doxo
Doxorubicin
Doxorubicin (USAN/INN)
Doxorubicin HCl
 
Doxorubicin Hydrochloride
Doxorubicin [USAN:INN:BAN]
Doxorubicin citrate
Doxorubicin hydrochloride (hydrochloride salt)
Doxorubicin-P4/D10
Doxorubicin-P4/D10 conjugate
Doxorubicin-hLL1
Doxorubicin-hLL1 conjugate
Doxorubicina
Doxorubicina [INN-Spanish]
Doxorubicine
Doxorubicine [INN-French]
Doxorubicinum
Doxorubicinum [INN-Latin]
EINECS 245-495-6
FI 106
Farmablastina (hydrochloride salt)
HMS2089H06
HSDB 3070
Hydroxydaunomycin hydrochlor ide (hydrochloride salt)
Hydroxydaunomycin hydrochloride (hydrochloride salt)
Hydroxydaunorubicin
Hydroxydaunorubicin hydrochloride (hydrochloride salt)
JT9100000
LMPK13050001
LS-1029
LS-165655
MLS000759533
Myocet
NCI-C01514
NChemBio.2007.10-comp13
NDC 38242-874
NIOSH/JT9100000
NSC 123127
Prestwick0_000438
Prestwick1_000438
Prestwick2_000438
Prestwick3_000438
Probes1_000151
Probes2_000129
RDF Rubex
Resmycin
Rubex
Rubex (hydrochloride salt)
SMP1_000106
SPBio_002395
TLC D-99
ThermoDox
Triferric doxorubicin
UNII-80168379AG
adiblastine (hydrochloride salt)
adr iablatina (hydrochloride salt)
adriablastine (hydrochloride salt)
adriablatina (hydrochloride salt)
adriblatina (hydrochloride salt)
doxorubicin
nchembio809-comp5
8
Dactinomycin4750-76-02019, 457193
Synonyms:
(- )-actinomycin d
(-)-actinomycin d
-pentone
01815_FLUKA
1H-Pyrrolo(2,1-1)-(1,4,7,10,13)oxatetraazacyclohexadecine
2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-I)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
50-76-0
A1410_SIGMA
A4262_SIGMA
A9415_SIGMA
AC1L1CQX
AC1L9W52
ACT
ACT D
ACTINOMYCIN D
ACTINOMYCIN D AMP
ACTINOMYCIN-D
ACTO-D
ACon0_000471
ACon1_001004
AD
AD (VAN)
AI3-26374
ActD
Actactinomycin A IV
Actactinomycin a Iv
Actinomycin 11 Cosmegen
Actinomycin 11 cosmegen
Actinomycin 7
Actinomycin A IV
Actinomycin Aiv
Actinomycin C (sub1)
Actinomycin C(sub1)
Actinomycin C1
Actinomycin D
Actinomycin D (JP15)
Actinomycin D deriv. of 3H-phenoxaocardazine
Actinomycin D, sodium deoxyribonucleic acid complex
Actinomycin I
Actinomycin I (sub1)
Actinomycin I(sub 1)
Actinomycin I(sub1)
Actinomycin I1
Actinomycin IV
Actinomycin Iv
Actinomycin X 1
Actinomycin X1
Actinomycin iv
Actinomycin-(threo-val-pro-sar-meval)
Actinomycin-?IV
Actinomycin-[threo-val-pro-sar-meval]
Actinomycindioic D Acid, Dilactone
Actinomycindioic D acid, dilactone
Acto-D
Antibiotic From Streptomyces Parvullus
Antibiotic from Streptomyces parvullus
BCBcMAP01_000155
BRD-A42383464-001-02-2
Bio1_000342
Bio1_000831
Bio1_001320
C06770
C1
C62H86N12O16
CBiol_002056
CCRIS 9
CHEBI:123721
CHEBI:27666
CHEMBL1554
CHEMBL427947
CID2019
 
CID457193
COSMEGEN (TN)
CPD000469227
Chounghwamycin B
Cosmegen
D Actinomycin
D00214
DACTINOMYCIN
DB00970
DVA-DPR-SAR-MVA-(c1)DTH-PXZ-(c11)DTH-DVA-DPR-SAR-MVA
Dactinomicina
Dactinomicina [INN-Spanish]
Dactinomycin
Dactinomycin (USP)
Dactinomycin D
Dactinomycin [USAN:BAN]
Dactinomycine
Dactinomycine [INN-French]
Dactinomycinum
Dactinomycinum [INN-Latin]
Dilactone Actinomycin D Acid
Dilactone Actinomycindioic D Acid
Dilactone actin omycindioic D acid
Dilactone actinomycin D acid
Dilactone actinomycindioic D acid
EINECS 200-063-6
FT-0080366
GNF-PF-1977
HBF 386
HBF 386 Meractinomycin
HBF 386 meractinomycin
HMS2052O17
HSDB 3220
LMPK14000005
LS-142
Lyovac Cosmegen
Lyovac cosmegen
MEGxm0_000350
MLS001424196
Meractinomycin
MolPort-001-739-741
MolPort-003-925-177
NCGC00025059-02
NCGC00090796-01
NCGC00161622-01
NCGC00161622-02
NCGC00169767-01
NCI-C04682
NCI60_030539
NP-005932
NSC 3053
NSC-3053
NSC191297
NSC3053
Neuro_000003
Oncostatin K
Oxamide
PXZ-THR-DVA-PRO-SAR-MVA-THR-DVA-PRO-SAR-MVA
SAM001246846
SMP1_000005
SMR000469227
UNII-1CC1JFE158
UPCMLD-DP055
UPCMLD-DP055:001
UPCMLD-DP055:002
WLN: 16- AN FVN IVN LVO PVM SVTJ G1 J1 KY1&1 N1 RY1&1
X 97
actd
actinomycin D
actinomycin cl
actinomycin x i
actinomyein-theo-val-pro-sar-meval
dactinomyein d
o)-(1-oxo-1,2-ethanediyl)]bis(N-methyl)L-valine
9Alkylating Agents4573
10
Cyclophosphamide275650-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Anhydrous cyclophosphamide
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
 
DB00531
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide

Interventional clinical trials:

idNameStatusNCT IDPhase
1Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial SarcomaRecruitingNCT02452554Phase 2
2Gene Mutation in Samples From Young Patients With Pleuropulmonary Blastoma Syndrome at Risk for Developing CancerCompletedNCT01353300
3Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer SyndromeRecruitingNCT00565903
4International Pleuropulmonary Blastoma (PPB) Treatment and Biology RegistryRecruitingNCT01464606
5DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History StudyRecruitingNCT01247597
6International Ovarian & Testicular Stromal Tumor RegistryRecruitingNCT01970696

Search NIH Clinical Center for Pulmonary Blastoma


Cochrane evidence based reviews: pulmonary blastoma

Genetic Tests for Pulmonary Blastoma

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Anatomical Context for Pulmonary Blastoma

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MalaCards organs/tissues related to Pulmonary Blastoma:

34
Lung, Brain, Fetal lung, Ovary, Thyroid, Liver, Lymph node

Animal Models for Pulmonary Blastoma or affiliated genes

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MGI Mouse Phenotypes related to Pulmonary Blastoma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.5DICER1, EGFR, KRAS, NKX2-1, TP53
2MP:00020068.5DICER1, EGFR, KRAS, NKX2-1, TP53
3MP:00030128.5DICER1, EGFR, KRAS, NKX2-1, TP53
4MP:00028737.8DICER1, EGFR, KRAS, NKX2-1, SYP, TP53
5MP:00053897.7CHGA, DICER1, EGFR, KRAS, NKX2-1, TP53
6MP:00053677.5CHGA, DICER1, EGFR, KRAS, TP53
7MP:00053797.3CHGA, DICER1, EGFR, KRAS, NKX2-1, TP53
8MP:00107687.0CHGA, DES, DICER1, EGFR, KRAS, NKX2-1
9MP:00053856.9CHGA, DES, DICER1, EGFR, KRAS, NKX2-1
10MP:00053766.9CHGA, DES, DICER1, EGFR, KRAS, NKX2-1

Publications for Pulmonary Blastoma

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Articles related to Pulmonary Blastoma:

(show top 50)    (show all 203)
idTitleAuthorsYear
1
Somatic DICER1 mutations in adult-onset pulmonary blastoma. (27126690)
2016
2
Pulmonary blastoma: a case report and brief review of the literature of tumor-induced hypoglycemia. (27532029)
2015
3
A case of biphasic pulmonary blastoma showing good response to preoperative chemotherapy. (26842180)
2014
4
Adult biphasic pulmonary blastoma. (23427368)
2013
5
Pulmonary blastoma: a rare primary lung malignancy. (23049565)
2012
6
Pulmonary blastoma with yolk sac elements. (21045461)
2010
7
Pulmonary blastoma in a neonate: a lesion distinct from pleuropulmonary blastoma with unique cytogenetic features. (19902198)
2010
8
A rare association; pulmonary blastoma developing on extrapulmonary sequestration basis. (20395246)
2010
9
Pulmonary blastoma metastatic to the ovary. (19047906)
2009
10
Pulmonary blastoma with endobronchial growth. (19333073)
2009
11
Biphasic pulmonary blastoma with germ cell differentiation in a 36-year-old man. (18827617)
2008
12
Biphagic pulmonary blastoma with a lesion of yolk sac tumor. (17642278)
2007
13
Survival of biphasic pulmonary blastoma. (16332433)
2006
14
Solitary brain metastasis from classic biphasic pulmonary blastoma: a case report and review of the literature. (17202827)
2006
15
Cyopathologic and histologic features of biphasic pulmonary blastoma: a case report. (15717762)
2005
16
Biphasic pulmonary blastoma presenting as endobronchial polyp with a long stalk. (15942110)
2005
17
Pulmonary blastoma: radiologic findings in five patients. (15050223)
2004
18
Expression of KIT (CD117) in biphasic pulmonary blastoma. Novel data on histogenesis. (14692559)
2003
19
Unexpected response of a pulmonary blastoma on radiotherapy: a case report and review of the literature. (11955657)
2002
20
Pulmonary blastoma. (11563261)
2001
21
Extension of a pulmonary blastoma into the left atrium. (11393507)
2001
22
Pulmonary blastoma: report of a case. (10211577)
1999
23
Pulmonary blastoma. (9495909)
1998
24
Pulmonary blastoma: case report of a patient with a 7-year remission and review of chemotherapy experience in the world literature. (9452262)
1998
25
Pulmonary blastoma in an adult. A case with rapid progression. (9802145)
1998
26
Resection and adjuvant chemotherapy of pulmonary blastoma. A case report. (8697409)
1996
27
Resection and adjuvant chemotherapy of pulmonary blastoma: a case report. (8635054)
1995
28
Pulmonary blastoma in an adult presenting as a chronic loculated effusion: a diagnostic problem. (8091334)
1994
29
Pulmonary blastoma presenting with massive hemothorax. (1322815)
1992
30
Pulmonary blastoma with a topographic transition from blastic to more differentiated areas. An immunohistochemical assessment of its embryonic nature using stage-specific embryonic antigens. (1661048)
1991
31
Pulmonary blastomas. (1849449)
1991
32
Pulmonary blastoma with germ cell (yolk sac) differentiation: report of two cases. (1722041)
1991
33
Persistent polyclonal B lymphocytosis with Epstein-Barr virus antibodies and subsequent malignant pulmonary blastoma. (1661303)
1991
34
Pulmonary blastoma with neuroendocrine differentiation in cell morules resembling neuroepithelial bodies. (2124206)
1990
35
Role of chemotherapy in pediatric pulmonary blastoma. (2152957)
1990
36
Pulmonary blastoma. (2176642)
1990
37
Pulmonary blastoma--report of a case. (2848950)
1988
38
Pleuropulmonary blastoma. The so-called pulmonary blastoma of childhood. (3048630)
1988
39
Pulmonary blastoma. Case report and literature review of chemotherapy experience. (6370414)
1984
40
Six cases of well-differentiated adenocarcinoma simulating fetal lung tubules in pseudoglandular stage. Comparison with pulmonary blastoma. (6496842)
1984
41
Pulmonary blastoma with hilar lymph node metastases: survival for 24 years. (7459803)
1981
42
Pulmonary blastoma. An ultrastructural study of a case and its transplanted tumor in athymic nude mice. (7417940)
1980
43
Pulmonary blastoma. (158135)
1979
44
Cytopathologic findings in pulmonary blastoma. (295162)
1979
45
Pulmonary blastoma. (199865)
1977
46
Pulmonary blastoma: report of two cases. (1126201)
1975
47
Pulmonary blastoma (embryoma lung). A case report with review of literature. (1193668)
1975
48
Pulmonary blastoma. A case report and review of the literature. (4811746)
1974
49
Pulmonary blastoma with diverse mesenchymal proliferation. (5075621)
1972
50
Pulmonary blastoma. A case report in an infant and review of the literature. (5013920)
1972

Variations for Pulmonary Blastoma

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Expression for genes affiliated with Pulmonary Blastoma

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Search GEO for disease gene expression data for Pulmonary Blastoma.

Pathways for genes affiliated with Pulmonary Blastoma

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Pathways related to Pulmonary Blastoma according to GeneCards Suite gene sharing:

(show all 21)
idSuper pathwaysScoreTop Affiliating Genes
19.5KRAS, TP53
29.4EGFR, TP53
39.3EGFR, KRAS
49.3EGFR, KRAS
5
Show member pathways
9.3EGFR, KRAS
69.3EGFR, KRAS
78.9EGFR, KRAS, TP53
8
Show member pathways
8.9EGFR, KRAS, TP53
9
Show member pathways
8.9EGFR, KRAS, TP53
10
Show member pathways
8.9EGFR, KRAS, TP53
118.9EGFR, KRAS, TP53
128.9EGFR, KRAS, TP53
138.9EGFR, KRAS, TP53
148.9EGFR, KRAS, TP53
158.9EGFR, KRAS, TP53
16
Show member pathways
8.9EGFR, KRAS, TP53
178.9EGFR, KRAS, TP53
188.9EGFR, KRAS, TP53
19
Show member pathways
8.9EGFR, KRAS, TP53
208.9EGFR, KRAS, TP53
218.6DICER1, EGFR, KRAS, TP53

GO Terms for genes affiliated with Pulmonary Blastoma

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Biological processes related to Pulmonary Blastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cerebral cortex cell migrationGO:00217959.5EGFR, NKX2-1
2ERBB2 signaling pathwayGO:00381289.5EGFR, KRAS
3regulation of long-term neuronal synaptic plasticityGO:00481699.5KRAS, SYP
4epithelial tube branching involved in lung morphogenesisGO:00604419.5KRAS, NKX2-1
5ovulation cycleGO:00426989.3CHGA, EGFR

Molecular functions related to Pulmonary Blastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:00428028.5DES, EGFR, SYP, TP53

Sources for Pulmonary Blastoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet