MCID: PLM032
MIFTS: 49

Pulmonary Blastoma malady

Categories: Respiratory diseases, Rare diseases, Cancer diseases

Aliases & Classifications for Pulmonary Blastoma

About this section
Sources:
11Disease Ontology, 13DISEASES, 31ICD10 via Orphanet, 39MeSH, 40MESH via Orphanet, 45NCIt, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Pulmonary Blastoma:

Name: Pulmonary Blastoma 11 54 50 39 13 68
Blastoma of Lung 11
 
Pneumoblastoma 54

Characteristics:

Orphanet epidemiological data:

54
pulmonary blastoma:
Inheritance: Multigenic/multifactorial; Age of onset: Adult; Age of death: adult

Classifications:



External Ids:

Disease Ontology11 DOID:4765
MeSH39 D018202
NCIt45 C3732
Orphanet54 ORPHA64741
SNOMED-CT62 189815007, 43149009
ICD10 via Orphanet31 C34.2, C34.8, C34.9 C34.1, C34.3, more
MESH via Orphanet40 D018202
UMLS via Orphanet69 C0206629

Summaries for Pulmonary Blastoma

About this section
Disease Ontology:11 An embryoma and malignant neoplasm of lung that derives from tissues of the lung and derives from pleura (a thin layer of tissue that covers the lungs and lines the interior wall of the chest cavity). It is most commonly effects children.

MalaCards based summary: Pulmonary Blastoma, also known as blastoma of lung, is related to pneumothorax and classic pulmonary blastoma, and has symptoms including coughing, dyspnea and fever. An important gene associated with Pulmonary Blastoma is NKX2-1 (NK2 Homeobox 1), and among its related pathways are Thyroid cancer and Gastric Cancer Network 2. Affiliated tissues include lung, brain and fetal lung, and related mouse phenotypes are neoplasm and no phenotypic analysis.

Related Diseases for Pulmonary Blastoma

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Diseases related to Pulmonary Blastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 189)
idRelated DiseaseScoreTop Affiliating Genes
1pneumothorax30.0DICER1, SYP
2classic pulmonary blastoma12.1
3epithelial predominant pulmonary blastoma11.9
4pleuropulmonary blastoma11.9
5blastoma10.8
6cervical benign neoplasm10.3SYP, TP53
7clear cell meningioma10.3SYP, TP53
8verruciform xanthoma of skin10.3DES, TP53
9blood group incompatibility10.3SYP, TP53
10mast-cell sarcoma10.3SYP, TP53
11olfactory neuroblastoma10.3SYP, TP53
12paraphimosis10.3SYP, TP53
13pineoblastoma10.3SYP, TP53
14tmem70 defect10.2NKX2-1, TP53
15gallbladder pleomorphic giant cell adenocarcinoma10.2SYP, TP53
16adult epithelioid sarcoma10.2SYP, TP53
17male reproductive system disease10.2DES, SYP
18porokeratosis10.2NKX2-1, TP53
19coronary stenosis10.2DES, TP53
20breast pericanalicular fibroadenoma10.2NKX2-1, TP53
21breast ductal carcinoma10.2KRAS, TP53
22sebaceous adenoma10.2DES, SYP
23mitochondrial neurogastrointestinal encephalopathy disease10.2KRAS, TP53
24bone benign neoplasm10.2SYP, TP53
25house allergic alveolitis10.2DES, TP53
26infantile thalamic degeneration10.2KRAS, TP53
27proliferative glomerulonephritis10.2DICER1, SYP
28adult syndrome10.2KRAS, TP53
29postpoliomyelitis syndrome10.2KRAS, TP53
30inhibited male orgasm10.2KRAS, TP53
31urethral cancer10.2DES, KRAS
32biliary papillomatosis10.2DES, KRAS
33wolffian adnexal neoplasm10.2EGFR, TP53
34nipple neoplasm10.2DICER1, SYP
35brain oligodendroglioma10.2SYP, TP53
36liver angiosarcoma10.2DES, DICER1
37rhabdomyosarcoma, embryonal, 210.2DICER1, TP53
38pelvic inflammatory disease10.2KRAS, SYP
39brainstem intraparenchymal clear cell meningioma10.2EGFR, TP53
40parachordoma10.2KRAS, NKX2-1
41giant cell tumor10.2KRAS, TP53
42uterine corpus endometrial stromal sarcoma10.2KRAS, TP53
43childhood embryonal testis carcinoma10.2EGFR, TP53
44papillary adenofibroma10.2KRAS, TP53
45childhood central nervous system primitive neuroectodermal neoplasm10.1SYP, TP53
46glomangioma10.1DES, SYP, TP53
47ossifying fibromyxoid tumor10.1KRAS, TP53
48childhood medulloblastoma10.1DES, SYP, TP53
49duodenal carcinoid syndrome10.1DES, EGFR
50spastic paraplegia 110.1EGFR, TP53

Graphical network of the top 20 diseases related to Pulmonary Blastoma:



Diseases related to pulmonary blastoma

Symptoms & Phenotypes for Pulmonary Blastoma

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Human phenotypes related to Pulmonary Blastoma:

 54 64 (show all 9)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 weight loss64 54 Frequent (79-30%) HP:0001824
2 fever64 54 Frequent (79-30%) HP:0001945
3 dyspnea64 54 Frequent (79-30%) HP:0002094
4 hemoptysis64 54 Very frequent (99-80%) HP:0002105
5 pulmonary infiltrates64 54 Very frequent (99-80%) HP:0002113
6 recurrent pneumonia64 54 Frequent (79-30%) HP:0006532
7 cough64 54 Very frequent (99-80%) HP:0012735
8 pleuropulmonary blastoma64 54 Very frequent (99-80%) HP:0100528
9 chest pain64 54 Very frequent (99-80%) HP:0100749

UMLS symptoms related to Pulmonary Blastoma:


coughing, dyspnea, fever, hemoptysis

MGI Mouse Phenotypes related to Pulmonary Blastoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.1DICER1, EGFR, KRAS, NKX2-1, TP53
2MP:00030129.1DICER1, EGFR, KRAS, NKX2-1, TP53
3MP:00053678.7CHGA, DICER1, EGFR, KRAS, TP53
4MP:00028738.6DICER1, EGFR, KRAS, NKX2-1, SYP, TP53
5MP:00053798.5CHGA, DICER1, EGFR, KRAS, NKX2-1, TP53
6MP:00053898.4CHGA, DICER1, EGFR, KRAS, NKX2-1, TP53
7MP:00053888.3DICER1, EGFR, KRAS, NKX2-1, TP53
8MP:00053857.7CHGA, DES, DICER1, EGFR, KRAS, NKX2-1
9MP:00053767.6CHGA, DES, DICER1, EGFR, KRAS, NKX2-1

Drugs & Therapeutics for Pulmonary Blastoma

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Drugs for Pulmonary Blastoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Trastuzumabapproved, investigationalPhase 2784180288-69-19903
Synonyms:
180288-69-1
Anti HER2
Anti-erbB2 Monoclonal Antibody
D03257
HER2 Monoclonal Antibody
Herceptin
 
Herceptin (TN)
Ig gamma-1 chain C region
Trastuzumab
Trastuzumab (INN)
Trastuzumab (genetical recombination)
Trastuzumab (genetical recombination) (JAN)
trastuzumab
2Antineoplastic Agents, PhytogenicPhase 25602
3Antimitotic AgentsPhase 25657
4AntibodiesPhase 26394
5Ado-trastuzumab emtansinePhase 268
6MaytansinePhase 275
7ImmunoglobulinsPhase 26394
8Antibodies, MonoclonalPhase 24039
9
Cyclophosphamideapproved, investigational293550-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Anhydrous cyclophosphamide
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
 
DB00531
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
10
Mechlorethamineapproved39751-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
 
KBioGR_001448
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
╬▓,╬▓'-dichlorodiethyl-N-methylamine
11
Dactinomycinapproved4850-76-02019, 457193
Synonyms:
(- )-actinomycin d
(-)-actinomycin d
-pentone
01815_FLUKA
1H-Pyrrolo(2,1-1)-(1,4,7,10,13)oxatetraazacyclohexadecine
2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-I)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
50-76-0
A1410_SIGMA
A4262_SIGMA
A9415_SIGMA
AC1L1CQX
AC1L9W52
ACT
ACT D
ACTINOMYCIN D
ACTINOMYCIN D AMP
ACTINOMYCIN-D
ACTO-D
ACon0_000471
ACon1_001004
AD
AD (VAN)
AI3-26374
ActD
Actactinomycin A IV
Actactinomycin a Iv
Actinomycin 11 Cosmegen
Actinomycin 11 cosmegen
Actinomycin 7
Actinomycin A IV
Actinomycin Aiv
Actinomycin C (sub1)
Actinomycin C(sub1)
Actinomycin C1
Actinomycin D
Actinomycin D (JP15)
Actinomycin D deriv. of 3H-phenoxaocardazine
Actinomycin D, sodium deoxyribonucleic acid complex
Actinomycin I
Actinomycin I (sub1)
Actinomycin I(sub 1)
Actinomycin I(sub1)
Actinomycin I1
Actinomycin IV
Actinomycin Iv
Actinomycin X 1
Actinomycin X1
Actinomycin iv
Actinomycin-(threo-val-pro-sar-meval)
Actinomycin-?IV
Actinomycin-[threo-val-pro-sar-meval]
Actinomycindioic D Acid, Dilactone
Actinomycindioic D acid, dilactone
Acto-D
Antibiotic From Streptomyces Parvullus
Antibiotic from Streptomyces parvullus
BCBcMAP01_000155
BRD-A42383464-001-02-2
Bio1_000342
Bio1_000831
Bio1_001320
C06770
C1
C62H86N12O16
CBiol_002056
CCRIS 9
CHEBI:123721
CHEBI:27666
CHEMBL1554
CHEMBL427947
CID2019
 
CID457193
COSMEGEN (TN)
CPD000469227
Chounghwamycin B
Cosmegen
D Actinomycin
D00214
DACTINOMYCIN
DB00970
DVA-DPR-SAR-MVA-(c1)DTH-PXZ-(c11)DTH-DVA-DPR-SAR-MVA
Dactinomicina
Dactinomicina [INN-Spanish]
Dactinomycin
Dactinomycin (USP)
Dactinomycin D
Dactinomycin [USAN:BAN]
Dactinomycine
Dactinomycine [INN-French]
Dactinomycinum
Dactinomycinum [INN-Latin]
Dilactone Actinomycin D Acid
Dilactone Actinomycindioic D Acid
Dilactone actin omycindioic D acid
Dilactone actinomycin D acid
Dilactone actinomycindioic D acid
EINECS 200-063-6
FT-0080366
GNF-PF-1977
HBF 386
HBF 386 Meractinomycin
HBF 386 meractinomycin
HMS2052O17
HSDB 3220
LMPK14000005
LS-142
Lyovac Cosmegen
Lyovac cosmegen
MEGxm0_000350
MLS001424196
Meractinomycin
MolPort-001-739-741
MolPort-003-925-177
NCGC00025059-02
NCGC00090796-01
NCGC00161622-01
NCGC00161622-02
NCGC00169767-01
NCI-C04682
NCI60_030539
NP-005932
NSC 3053
NSC-3053
NSC191297
NSC3053
Neuro_000003
Oncostatin K
Oxamide
PXZ-THR-DVA-PRO-SAR-MVA-THR-DVA-PRO-SAR-MVA
SAM001246846
SMP1_000005
SMR000469227
UNII-1CC1JFE158
UPCMLD-DP055
UPCMLD-DP055:001
UPCMLD-DP055:002
WLN: 16- AN FVN IVN LVO PVM SVTJ G1 J1 KY1&1 N1 RY1&1
X 97
actd
actinomycin D
actinomycin cl
actinomycin x i
actinomyein-theo-val-pro-sar-meval
dactinomyein d
o)-(1-oxo-1,2-ethanediyl)]bis(N-methyl)L-valine
12
Vincristineapproved, investigational9222068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
13
Ifosfamideapproved4003778-73-23690
Synonyms:
(+-)-Ifosfamid
(+-)-Ifosphamide
(+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
(D,L)-Ifosfamide
(R,S)-Ifosphamide
(R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd
2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI)
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
3,} 2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
36341-88-5
3778-73-2
84711-20-6
A 4942
AB00513932
AC-2113
AC1L1GHW
ASTA Z 4942
Ambap3778-73-2
Asta Z 4942
BPBio1_000865
BRN 0611835
BSPBio_000785
C07047
CAS-3778-73-2
CCRIS 352
CHEBI:5864
CHEMBL1024
CID3690
Cyfos
D00343
D007069
DB01181
EINECS 223-237-3
HMS1570H07
HMS2090M12
HMS2093N07
HSDB 7023
Holoxan
Holoxan 1000
I-Phosphamide
I06-0494
IFEX (TN)
Ifex
Ifosfamid
Ifosfamida
Ifosfamida [INN-Spanish]
Ifosfamide (JAN/USP/INN)
 
Ifosfamide Sterile
Ifosfamide [USAN:INN:BAN:JAN]
Ifosfamidum
Ifosfamidum [INN-Latin]
Ifosphamide
Ifsofamide
Iphosphamid
Iphosphamid(e)
Iphosphamide
Iso Endoxan
Iso-Endoxan
Isoendoxan
Isofosfamide
Isophosphamide
Isosfamide
LS-102
LS-99799
MJF 9325
MJF-9325
MLS002154021
Mitoxana
Mitoxana, Ifex, Ifosfamide
MolPort-003-666-704
N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide
N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine
NCGC00016639-01
NCGC00179435-01
NCI-C01638
NCI60_000233
NPFAPI-04
NSC 109,724
NSC 109724
NSC-109,724
NSC-109724
NSC109,724
NSC109724
Naxamide
Prestwick0_000833
Prestwick1_000833
Prestwick2_000833
Prestwick3_000833
S1302_Selleck
SMR001233348
SPBio_002706
STL058690
UNII-UM20QQM95Y
WLN: T6NPOTJ AM2G BO B2G
Z 4942
Z-4942
Z4942
ifosfamide
isosfamide
{3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,
14
Doxorubicinapproved, investigational175123214-92-831703
Synonyms:
(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(8S-cis)-10-((3-amino-2,3,6-Trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
111266-55-8
14-Hydroxydaunomycin
14-Hydroxydaunorubicine
14-hydroxydaunomycin
14-hydroxydaunorubicine
23214-92-8
23257-17-2
24385-08-8
25311-50-6
25316-40-9
25316-40-9 (hydrochloride)
29042-30-6
AC1L1M5T
AC1Q29OJ
ADM
ADR
Adriablastin
Adriacin (hydrochloride salt)
Adriamycin
Adriamycin PFS
Adriamycin PFS (hydrochloride salt)
Adriamycin RDF
Adriamycin RDF (hydrochloride salt)
Adriamycin Semiquinone
Adriamycin semiquinone
Adriblas tina
Adriblastin
Adriblastina
Adriblastina (TN)
Adriblastina (hydrochloride salt)
Aerosolized Doxorubicin
BPBio1_000502
BRD-K92093830-003-04-3
BSPBio_000456
BSPBio_001031
C01661
C27H29NO11
CCRIS 739
CHEBI:28748
CHEMBL179
CID31703
Caelyx
Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74
Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120
D03899
DB00997
DM2
DOX-SL
Doxil
Doxo
Doxorubicin
Doxorubicin (USAN/INN)
Doxorubicin HCl
 
Doxorubicin Hydrochloride
Doxorubicin [USAN:INN:BAN]
Doxorubicin citrate
Doxorubicin hydrochloride (hydrochloride salt)
Doxorubicin-P4/D10
Doxorubicin-P4/D10 conjugate
Doxorubicin-hLL1
Doxorubicin-hLL1 conjugate
Doxorubicina
Doxorubicina [INN-Spanish]
Doxorubicine
Doxorubicine [INN-French]
Doxorubicinum
Doxorubicinum [INN-Latin]
EINECS 245-495-6
FI 106
Farmablastina (hydrochloride salt)
HMS2089H06
HSDB 3070
Hydroxydaunomycin hydrochlor ide (hydrochloride salt)
Hydroxydaunomycin hydrochloride (hydrochloride salt)
Hydroxydaunorubicin
Hydroxydaunorubicin hydrochloride (hydrochloride salt)
JT9100000
LMPK13050001
LS-1029
LS-165655
MLS000759533
Myocet
NCI-C01514
NChemBio.2007.10-comp13
NDC 38242-874
NIOSH/JT9100000
NSC 123127
Prestwick0_000438
Prestwick1_000438
Prestwick2_000438
Prestwick3_000438
Probes1_000151
Probes2_000129
RDF Rubex
Resmycin
Rubex
Rubex (hydrochloride salt)
SMP1_000106
SPBio_002395
TLC D-99
ThermoDox
Triferric doxorubicin
UNII-80168379AG
adiblastine (hydrochloride salt)
adr iablatina (hydrochloride salt)
adriablastine (hydrochloride salt)
adriablatina (hydrochloride salt)
adriblatina (hydrochloride salt)
doxorubicin
nchembio809-comp5
15
DoxilApproved June 1999175131703
Synonyms:
Dox-SL
Doxil
 
Evacet
LipoDox
Pegylated Liposomal Doxorubicin Hydrochloride
liposomal doxorubicin
16Topoisomerase Inhibitors5069
17Immunosuppressive Agents13086
18Nucleic Acid Synthesis Inhibitors4962
19Isophosphamide mustard400
20Antineoplastic Agents, Alkylating4603
21Alkylating Agents4827
22Anti-Bacterial Agents11226
23Antibiotics, Antitubercular7180
24Anti-Infective Agents22062
25Antirheumatic Agents10956

Interventional clinical trials:

idNameStatusNCT IDPhase
1Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial SarcomaActive, not recruitingNCT02452554Phase 2
2Gene Mutation in Samples From Young Patients With Pleuropulmonary Blastoma Syndrome at Risk for Developing CancerCompletedNCT01353300
3Review of the Paediatric Pleuropulmonary Blastoma French SeriesRecruitingNCT03044834
4International Pleuropulmonary Blastoma (PPB) Treatment and Biology RegistryRecruitingNCT01464606
5Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer SyndromeRecruitingNCT00565903
6DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History StudyRecruitingNCT01247597
7Congenital Lung Anomalies (CLA) Swiss DatabaseRecruitingNCT03044769
8International Ovarian & Testicular Stromal Tumor RegistryRecruitingNCT01970696

Search NIH Clinical Center for Pulmonary Blastoma


Cochrane evidence based reviews: pulmonary blastoma

Genetic Tests for Pulmonary Blastoma

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Anatomical Context for Pulmonary Blastoma

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MalaCards organs/tissues related to Pulmonary Blastoma:

36
Lung, Brain, Fetal lung, Ovary, Thyroid, Liver, Lymph node

Publications for Pulmonary Blastoma

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Articles related to Pulmonary Blastoma:

(show top 50)    (show all 205)
idTitleAuthorsYear
1
A retrospective analysis of the clinicopathological and molecular characteristics of pulmonary blastoma. (27877056)
2016
2
Biphasic Pulmonary Blastoma Associated with Cerebral Metastasis. (26768884)
2016
3
Somatic DICER1 mutations in adult-onset pulmonary blastoma. (27126690)
2016
4
What do we know about pulmonary blastoma?: review of literature and clinical case report. (28008207)
2016
5
Pulmonary blastoma: a case report and brief review of the literature of tumor-induced hypoglycemia. (27532029)
2015
6
Classic biphasic pulmonary blastoma with brain and axillary metastases: a case report with molecular analysis and review of literature. (25755806)
2015
7
Neoadjuvant Chemoradiotherapy Treatment for a Classic Biphasic Pulmonary Blastoma with High PD-L1 Expression. (26254381)
2015
8
Unresectable Middle Mediastinal Biphasic Pulmonary Blastoma. (26504071)
2015
9
A Case of Biphasic Pulmonary Blastoma Treated with Carboplatin and Paclitaxel plus Bevacizumab. (26075125)
2015
10
Pulmonary blastoma: a case report and review of the literature. (24885892)
2014
11
Surgery and radiation therapy for brain metastases from classic biphasic pulmonary blastoma. (24895392)
2014
12
Biphasic pulmonary blastoma: An unusual presentation with chest wall, rib, and pleural involvement. (24669096)
2014
13
Discoid lupus and pulmonary blastoma in an elderly patient. (24771745)
2014
14
Adult pulmonary blastoma: Report of an unusual malignant lung tumor. (25493248)
2014
15
A case of biphasic pulmonary blastoma showing good response to preoperative chemotherapy. (26842180)
2014
16
Primary pulmonary blastoma of monophasic variety--diagnosis and management. (23758909)
2013
17
18F-FDG PET/CT appearances of adult pulmonary blastoma. (23751833)
2013
18
Classic Biphasic Pulmonary Blastoma Demonstrated by 18F-FDG PET/CT. (23989445)
2013
19
Adult biphasic pulmonary blastoma. (23427368)
2013
20
A rare occurrence of biphasic pulmonary blastoma in an elderly male. (24023328)
2013
21
Radiographic illusion of cardiomegaly resulting from a pulmonary blastoma in a patient imaged for evaluation of chronic bronchitis. (23887987)
2013
22
Pulmonary blastoma with submandibular, scrotum and adrenal metastases: case report. (21447935)
2012
23
Pulmonary blastoma: a rare primary lung malignancy. (23049565)
2012
24
Pulmonary blastoma in a young adult. (23008928)
2012
25
Classic pulmonary blastoma: a subtype of biphasic pulmonary blastoma. (22001215)
2012
26
Pulmonary blastoma in adult: dramatic but transient response to doxorubicin plus ifosfamide. (20670092)
2011
27
Pneumothorax in a child with pulmonary blastoma. (21349540)
2011
28
Classic biphasic pulmonary blastoma: a case report and review of the literature. (21513998)
2011
29
Establishment and phenotypic characterization of the first human pulmonary blastoma cell line. (20724021)
2011
30
Expression and mutation analysis of EGFR, c-KIT, and I^-catenin in pulmonary blastoma. (21292787)
2011
31
Fine-needle aspiration of classic biphasic pulmonary blastoma. (19937760)
2010
32
Pulmonary blastoma in a neonate: a lesion distinct from pleuropulmonary blastoma with unique cytogenetic features. (19902198)
2010
33
Preoperative radiation therapy and chemotherapy for pulmonary blastoma: a case report. (20101153)
2010
34
Pulmonary blastoma with yolk sac elements. (21045461)
2010
35
A rare association; pulmonary blastoma developing on extrapulmonary sequestration basis. (20395246)
2010
36
Pulmonary blastoma metastatic to the ovary. (19047906)
2009
37
Clinical, pathological and immunohistochemical features of a pulmonary blastoma in a horse. (19202177)
2009
38
Pulmonary blastoma with endobronchial growth. (19333073)
2009
39
Biphasic pulmonary blastoma with rapid progression. (19214452)
2009
40
Cytologic features of pulmonary blastoma. (21938157)
2009
41
Biphasic pulmonary blastoma with germ cell differentiation in a 36-year-old man. (18827617)
2008
42
Radical resection of a pulmonary blastoma involving the pulmonary artery. (18579394)
2008
43
Clinicopathological and immunohistochemical features of pulmonary blastoma: analysis of 4 cases and review of the literature]. (17672968)
2007
44
Pulmonary blastoma. (17686364)
2007
45
Clonality and heterogeneity of pulmonary blastoma from the viewpoint of genetic alterations: a case report. (17350138)
2007
46
Biphagic pulmonary blastoma with a lesion of yolk sac tumor. (17642278)
2007
47
Pulmonary blastoma with renal metastasis responds to sorafenib. (17409808)
2007
48
Prognostic factors in pleuro-pulmonary blastoma. (16619221)
2007
49
Biphasic pulmonary blastoma: report of a case. (17392670)
2007
50
Combined small cell carcinoma with pulmonary blastoma and adenocarcinoma: case report and clonality analysis. (17046168)
2006

Variations for Pulmonary Blastoma

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Expression for genes affiliated with Pulmonary Blastoma

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Search GEO for disease gene expression data for Pulmonary Blastoma.

Pathways for genes affiliated with Pulmonary Blastoma

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Pathways related to Pulmonary Blastoma according to GeneCards Suite gene sharing:

(show all 21)
idSuper pathwaysScoreTop Affiliating Genes
19.6KRAS, TP53
29.6EGFR, TP53
39.5EGFR, KRAS
49.5EGFR, KRAS
59.5EGFR, KRAS
6
Show member pathways
9.5EGFR, KRAS
79.1EGFR, KRAS, TP53
89.1EGFR, KRAS, TP53
9
Show member pathways
9.1EGFR, KRAS, TP53
10
Show member pathways
9.1EGFR, KRAS, TP53
11
Show member pathways
9.1EGFR, KRAS, TP53
12
Show member pathways
9.1EGFR, KRAS, TP53
13
Show member pathways
9.1EGFR, KRAS, TP53
149.1EGFR, KRAS, TP53
15
Show member pathways
9.1EGFR, KRAS, TP53
169.1EGFR, KRAS, TP53
179.1EGFR, KRAS, TP53
189.1EGFR, KRAS, TP53
199.1EGFR, KRAS, TP53
20
Show member pathways
8.7DES, EGFR, KRAS
218.6DICER1, EGFR, KRAS, TP53

GO Terms for genes affiliated with Pulmonary Blastoma

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Biological processes related to Pulmonary Blastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1epithelial tube branching involved in lung morphogenesisGO:006044110.1KRAS, NKX2-1
2cerebral cortex cell migrationGO:002179510.1EGFR, NKX2-1
3ERBB2 signaling pathwayGO:00381289.8EGFR, KRAS
4regulation of long-term neuronal synaptic plasticityGO:00481699.6KRAS, SYP

Molecular functions related to Pulmonary Blastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:00428028.3DES, EGFR, SYP, TP53

Sources for Pulmonary Blastoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet