MCID: PLM032
MIFTS: 44

Pulmonary Blastoma malady

Respiratory diseases, Cancer diseases, Rare diseases categories

Aliases & Classifications for Pulmonary Blastoma

About this section
Sources:
10Disease Ontology, 47Novoseek, 51Orphanet, 65UMLS, 36MeSH, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet
See all sources

Aliases & Descriptions for Pulmonary Blastoma:

Name: Pulmonary Blastoma 10 47 51 65 36
Blastoma of Lung 10
 
Pneumoblastoma 51


Classifications:



Characteristics (Orphanet epidemiological data):

51
pulmonary blastoma:
Inheritance: Multigenic/multifactorial; Age of onset: Adult; Age of death: adult


External Ids:

Disease Ontology10 DOID:4765
NCIt42 C3732
MeSH36 D018202
Orphanet51 64741
SNOMED-CT59 43149009, 189815007
ICD10 via Orphanet28 C34
MESH via Orphanet37 D018202
UMLS via Orphanet66 C0206629

Summaries for Pulmonary Blastoma

About this section
Disease Ontology:10 An embryoma and malignant neoplasm of lung that derives from tissues of the lung and derives from pleura (a thin layer of tissue that covers the lungs and lines the interior wall of the chest cavity). it is most commonly effects children.

MalaCards based summary: Pulmonary Blastoma, also known as blastoma of lung, is related to blastoma and pleuropulmonary blastoma, and has symptoms including hemoptysis, neoplasm of the lung and chest pain. An important gene associated with Pulmonary Blastoma is NKX2-1 (NK2 Homeobox 1), and among its related pathways are Thyroid cancer and Gastric cancer network 2. Affiliated tissues include lung, brain and fetal lung, and related mouse phenotypes are limbs/digits/tail and respiratory system.

Related Diseases for Pulmonary Blastoma

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Diseases related to Pulmonary Blastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 220)
idRelated DiseaseScoreTop Affiliating Genes
1blastoma11.2
2pleuropulmonary blastoma10.5
3classic pulmonary blastoma10.5
4epithelial predominant pulmonary blastoma10.4
5body dysmorphic disorder10.3DICER1, SYP
6goiter, multinodular 1, with or without sertoli-leydig cell tumors10.3DICER1, TP53
7monophasic synovial sarcoma10.3SYP, TP53
8choanal atresia10.2SYP, TP53
9cerebral arterial disease10.2SYP, TP53
10cerebrovascular disease10.2SYP, TP53
11cervical adenitis10.2SYP, TP53
12survival motor neuron spinal muscular atrophy10.2SYP, TP53
13rhabdoid meningioma10.2SYP, TP53
14acute laryngopharyngitis10.2DES, DICER1
15spinal cord oligodendroglioma10.2SYP, TP53
16pituitary adenoma10.2DICER1, SYP
17childhood leukemia10.2SYP, TP53
18central nervous system primitive neuroectodermal neoplasm10.2SYP, TP53
19pleural cancer10.2DES, TP53
20steatitis10.2SYP, TP53
21laryngeal mucoepidermoid carcinoma10.2DES, TP53
22autoimmune hemolytic anemia10.2SYP, TP53
23ovary adenocarcinoma10.2DES, SYP
24embryoma10.2
25spindle cell carcinoma10.2
26adenocarcinoma10.2
27pneumothorax10.2
28autosomal dominant charcot-marie-tooth disease type 2a210.2DES, TP53
29thyroid cancer, childhood10.2NKX2-1, TP53
30lens-induced iridocyclitis10.2CHGA, TP53
31basal cell carcinoma 710.2CHGA, TP53
32adult leptomeningeal melanoma10.2SYP, TP53
33endometrial stromal sarcoma10.2CHGA, SYP
34rift valley fever10.2DES, SYP
35pathological gambling10.2NKX2-1, TP53
36flat retinoschisis10.2CHGA, SYP
37cauda equina intradural extramedullary astrocytoma10.2SYP, TP53
38mast cell neoplasm10.2NKX2-1, TP53
39ureter small cell carcinoma10.2CHGA, SYP
40third-degree atrioventricular block10.2CHGA, SYP
41auditory system disease10.2CHGA, SYP
42mesenchymoma10.2DES, SYP
43anterior scleritis10.2CHGA, TP53
44gallbladder endocrine tumor10.2CHGA, SYP
45peritoneum cancer10.2CHGA, SYP
46embryonal tumor with multilayered rosettes10.2DES, TP53
47cervical incompetence10.2CHGA, SYP
48ophthalmia neonatorum10.2CHGA, SYP
49subpulmonary stenosis10.2CHGA, SYP
50oligodendroglioma10.2CHGA, SYP

Graphical network of the top 20 diseases related to Pulmonary Blastoma:



Diseases related to pulmonary blastoma

Symptoms for Pulmonary Blastoma

About this section

Symptoms:

 51 (show all 10)
  • radiologic lung abnormalities/changes
  • thoracic/chest pain
  • cough
  • hemoptysis
  • lung/bronchopulmonary neoplasm/tumor/carcinoma/cancer
  • respiratory distress/dyspnea/respiratory failure/lung volume reduction
  • repeat respiratory infections
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • fever/chilling
  • abnormal pleura/hydrothorax/pleuresia/pleural effusion/chylothorax

HPO human phenotypes related to Pulmonary Blastoma:

(show all 8)
id Description Frequency HPO Source Accession
1 hemoptysis hallmark (90%) HP:0002105
2 neoplasm of the lung hallmark (90%) HP:0100526
3 chest pain hallmark (90%) HP:0100749
4 weight loss typical (50%) HP:0001824
5 respiratory insufficiency typical (50%) HP:0002093
6 recurrent respiratory infections typical (50%) HP:0002205
7 abnormality of temperature regulation typical (50%) HP:0004370
8 abnormality of the pleura occasional (7.5%) HP:0002103

Drugs & Therapeutics for Pulmonary Blastoma

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Drugs for Pulmonary Blastoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
ado-trastuzumab emtansineapprovedPhase 2571018448-65-1
Synonyms:
Kadcyla
 
Trastuzumab-DM1
trastuzumab emtansine
trastuzumab-MCC-DM1
2
Trastuzumabapproved, investigationalPhase 2688180288-69-19903
Synonyms:
180288-69-1
Anti HER2
Anti-erbB2 Monoclonal Antibody
D03257
HER2 Monoclonal Antibody
Herceptin
 
Herceptin (TN)
Ig gamma-1 chain C region
Trastuzumab
Trastuzumab (INN)
Trastuzumab (genetical recombination)
Trastuzumab (genetical recombination) (JAN)
trastuzumab
3MaytansinePhase 245
4
Ifosfamideapproved3583778-73-23690
Synonyms:
(+-)-Ifosfamid
(+-)-Ifosphamide
(+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
(D,L)-Ifosfamide
(R,S)-Ifosphamide
(R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd
2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI)
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
3,} 2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
36341-88-5
3778-73-2
84711-20-6
A 4942
AB00513932
AC-2113
AC1L1GHW
ASTA Z 4942
Ambap3778-73-2
Asta Z 4942
BPBio1_000865
BRN 0611835
BSPBio_000785
C07047
CAS-3778-73-2
CCRIS 352
CHEBI:5864
CHEMBL1024
CID3690
Cyfos
D00343
D007069
DB01181
EINECS 223-237-3
HMS1570H07
HMS2090M12
HMS2093N07
HSDB 7023
Holoxan
Holoxan 1000
I-Phosphamide
I06-0494
IFEX (TN)
Ifex
Ifosfamid
Ifosfamida
Ifosfamida [INN-Spanish]
Ifosfamide
 
Ifosfamide (JAN/USP/INN)
Ifosfamide Sterile
Ifosfamide [USAN:INN:BAN:JAN]
Ifosfamidum
Ifosfamidum [INN-Latin]
Ifosphamide
Ifsofamide
Iphosphamid
Iphosphamid(e)
Iphosphamide
Iso Endoxan
Iso-Endoxan
Isoendoxan
Isofosfamide
Isophosphamide
Isosfamide
LS-102
LS-99799
MJF 9325
MJF-9325
MLS002154021
Mitoxana
Mitoxana, Ifex, Ifosfamide
MolPort-003-666-704
N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide
N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine
NCGC00016639-01
NCGC00179435-01
NCI-C01638
NCI60_000233
NPFAPI-04
NSC 109,724
NSC 109724
NSC-109,724
NSC-109724
NSC109,724
NSC109724
Naxamide
Prestwick0_000833
Prestwick1_000833
Prestwick2_000833
Prestwick3_000833
S1302_Selleck
SMR001233348
SPBio_002706
STL058690
UNII-UM20QQM95Y
WLN: T6NPOTJ AM2G BO B2G
Z 4942
Z-4942
Z4942
ifosfamide
isosfamide
{3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,
5
Vincristineapproved, investigational8362068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
6
Doxorubicinapproved, investigational152523214-92-831703
Synonyms:
(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(8S-cis)-10-((3-amino-2,3,6-Trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
111266-55-8
14-Hydroxydaunomycin
14-Hydroxydaunorubicine
14-hydroxydaunomycin
14-hydroxydaunorubicine
23214-92-8
23257-17-2
24385-08-8
25311-50-6
25316-40-9
25316-40-9 (hydrochloride)
29042-30-6
AC1L1M5T
AC1Q29OJ
ADM
ADR
Adriablastin
Adriacin (hydrochloride salt)
Adriamycin
Adriamycin PFS
Adriamycin PFS (hydrochloride salt)
Adriamycin RDF
Adriamycin RDF (hydrochloride salt)
Adriamycin Semiquinone
Adriamycin semiquinone
Adriblas tina
Adriblastin
Adriblastina
Adriblastina (TN)
Adriblastina (hydrochloride salt)
Aerosolized Doxorubicin
BPBio1_000502
BRD-K92093830-003-04-3
BSPBio_000456
BSPBio_001031
C01661
C27H29NO11
CCRIS 739
CHEBI:28748
CHEMBL179
CID31703
Caelyx
Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74
Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120
D03899
DB00997
DM2
DOX-SL
Doxil
Doxo
Doxorubicin
Doxorubicin (USAN/INN)
Doxorubicin HCl
 
Doxorubicin Hydrochloride
Doxorubicin [USAN:INN:BAN]
Doxorubicin citrate
Doxorubicin hydrochloride (hydrochloride salt)
Doxorubicin-P4/D10
Doxorubicin-P4/D10 conjugate
Doxorubicin-hLL1
Doxorubicin-hLL1 conjugate
Doxorubicina
Doxorubicina [INN-Spanish]
Doxorubicine
Doxorubicine [INN-French]
Doxorubicinum
Doxorubicinum [INN-Latin]
EINECS 245-495-6
FI 106
Farmablastina (hydrochloride salt)
HMS2089H06
HSDB 3070
Hydroxydaunomycin hydrochlor ide (hydrochloride salt)
Hydroxydaunomycin hydrochloride (hydrochloride salt)
Hydroxydaunorubicin
Hydroxydaunorubicin hydrochloride (hydrochloride salt)
JT9100000
LMPK13050001
LS-1029
LS-165655
MLS000759533
Myocet
NCI-C01514
NChemBio.2007.10-comp13
NDC 38242-874
NIOSH/JT9100000
NSC 123127
Prestwick0_000438
Prestwick1_000438
Prestwick2_000438
Prestwick3_000438
Probes1_000151
Probes2_000129
RDF Rubex
Resmycin
Rubex
Rubex (hydrochloride salt)
SMP1_000106
SPBio_002395
TLC D-99
ThermoDox
Triferric doxorubicin
UNII-80168379AG
adiblastine (hydrochloride salt)
adr iablatina (hydrochloride salt)
adriablastine (hydrochloride salt)
adriablatina (hydrochloride salt)
adriblatina (hydrochloride salt)
doxorubicin
nchembio809-comp5
7
Dactinomycinapproved4650-76-02019, 457193
Synonyms:
(- )-actinomycin d
(-)-actinomycin d
-pentone
01815_FLUKA
1H-Pyrrolo(2,1-1)-(1,4,7,10,13)oxatetraazacyclohexadecine
2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-I)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
50-76-0
A1410_SIGMA
A4262_SIGMA
A9415_SIGMA
AC1L1CQX
AC1L9W52
ACT
ACT D
ACTINOMYCIN D
ACTINOMYCIN D AMP
ACTINOMYCIN-D
ACTO-D
ACon0_000471
ACon1_001004
AD
AD (VAN)
AI3-26374
ActD
Actactinomycin A IV
Actactinomycin a Iv
Actinomycin 11 Cosmegen
Actinomycin 11 cosmegen
Actinomycin 7
Actinomycin A IV
Actinomycin Aiv
Actinomycin C (sub1)
Actinomycin C(sub1)
Actinomycin C1
Actinomycin D
Actinomycin D (JP15)
Actinomycin D deriv. of 3H-phenoxaocardazine
Actinomycin D, sodium deoxyribonucleic acid complex
Actinomycin I
Actinomycin I (sub1)
Actinomycin I(sub 1)
Actinomycin I(sub1)
Actinomycin I1
Actinomycin IV
Actinomycin Iv
Actinomycin X 1
Actinomycin X1
Actinomycin iv
Actinomycin-(threo-val-pro-sar-meval)
Actinomycin-?IV
Actinomycin-[threo-val-pro-sar-meval]
Actinomycindioic D Acid, Dilactone
Actinomycindioic D acid, dilactone
Acto-D
Antibiotic From Streptomyces Parvullus
Antibiotic from Streptomyces parvullus
BCBcMAP01_000155
BRD-A42383464-001-02-2
Bio1_000342
Bio1_000831
Bio1_001320
C06770
C1
C62H86N12O16
CBiol_002056
CCRIS 9
CHEBI:123721
CHEBI:27666
CHEMBL1554
CHEMBL427947
CID2019
 
CID457193
COSMEGEN (TN)
CPD000469227
Chounghwamycin B
Cosmegen
D Actinomycin
D00214
DACTINOMYCIN
DB00970
DVA-DPR-SAR-MVA-(c1)DTH-PXZ-(c11)DTH-DVA-DPR-SAR-MVA
Dactinomicina
Dactinomicina [INN-Spanish]
Dactinomycin
Dactinomycin (USP)
Dactinomycin D
Dactinomycin [USAN:BAN]
Dactinomycine
Dactinomycine [INN-French]
Dactinomycinum
Dactinomycinum [INN-Latin]
Dilactone Actinomycin D Acid
Dilactone Actinomycindioic D Acid
Dilactone actin omycindioic D acid
Dilactone actinomycin D acid
Dilactone actinomycindioic D acid
EINECS 200-063-6
FT-0080366
GNF-PF-1977
HBF 386
HBF 386 Meractinomycin
HBF 386 meractinomycin
HMS2052O17
HSDB 3220
LMPK14000005
LS-142
Lyovac Cosmegen
Lyovac cosmegen
MEGxm0_000350
MLS001424196
Meractinomycin
MolPort-001-739-741
MolPort-003-925-177
NCGC00025059-02
NCGC00090796-01
NCGC00161622-01
NCGC00161622-02
NCGC00169767-01
NCI-C04682
NCI60_030539
NP-005932
NSC 3053
NSC-3053
NSC191297
NSC3053
Neuro_000003
Oncostatin K
Oxamide
PXZ-THR-DVA-PRO-SAR-MVA-THR-DVA-PRO-SAR-MVA
SAM001246846
SMP1_000005
SMR000469227
UNII-1CC1JFE158
UPCMLD-DP055
UPCMLD-DP055:001
UPCMLD-DP055:002
WLN: 16- AN FVN IVN LVO PVM SVTJ G1 J1 KY1&1 N1 RY1&1
X 97
actd
actinomycin D
actinomycin cl
actinomycin x i
actinomyein-theo-val-pro-sar-meval
dactinomyein d
o)-(1-oxo-1,2-ethanediyl)]bis(N-methyl)L-valine
8
Cyclophosphamideapproved, investigational252550-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
DB00531
 
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
9
DoxilApproved June 1999152531703
Synonyms:
Dox-SL
Doxil
 
Evacet
LipoDox
Pegylated Liposomal Doxorubicin Hydrochloride
liposomal doxorubicin
10Isophosphamide mustard358

Interventional clinical trials:

idNameStatusNCT IDPhase
1Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial SarcomaSuspendedNCT02452554Phase 2
2Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer SyndromeRecruitingNCT00565903
3International Pleuropulmonary Blastoma (PPB) Treatment and Biology RegistryRecruitingNCT01464606
4DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History StudyRecruitingNCT01247597
5International Ovarian & Testicular Stromal Tumor RegistryRecruitingNCT01970696
6Gene Mutation in Samples From Young Patients With Pleuropulmonary Blastoma Syndrome at Risk for Developing CancerActive, not recruitingNCT01353300

Search NIH Clinical Center for Pulmonary Blastoma


Cochrane evidence based reviews: Pulmonary Blastoma

Genetic Tests for Pulmonary Blastoma

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Anatomical Context for Pulmonary Blastoma

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MalaCards organs/tissues related to Pulmonary Blastoma:

33
Lung, Brain, Fetal lung, Ovary, Thyroid, Liver, Lymph node

Animal Models for Pulmonary Blastoma or affiliated genes

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MGI Mouse Phenotypes related to Pulmonary Blastoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.9DICER1, EGFR, KRAS, TP53
2MP:00053888.3DICER1, EGFR, KRAS, NKX2-1, TP53
3MP:00020068.2DICER1, EGFR, KRAS, NKX2-1, TP53
4MP:00053677.9CHGA, DICER1, EGFR, KRAS, TP53
5MP:00053797.4CHGA, DICER1, EGFR, KRAS, NKX2-1, TP53
6MP:00053897.1CHGA, DICER1, EGFR, KRAS, NKX2-1, TP53
7MP:00053857.1CHGA, DES, DICER1, EGFR, KRAS, NKX2-1
8MP:00107687.0CHGA, DES, DICER1, EGFR, KRAS, NKX2-1
9MP:00053766.8CHGA, DES, DICER1, EGFR, KRAS, NKX2-1

Publications for Pulmonary Blastoma

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Articles related to Pulmonary Blastoma:

(show top 50)    (show all 198)
idTitleAuthorsYear
1
Adult biphasic pulmonary blastoma. (23427368)
2013
2
18F-FDG PET/CT appearances of adult pulmonary blastoma. (23751833)
2013
3
Expression and mutation analysis of EGFR, c-KIT, and I^-catenin in pulmonary blastoma. (21292787)
2011
4
Pulmonary blastoma with yolk sac elements. (21045461)
2010
5
Pulmonary blastoma in a neonate: a lesion distinct from pleuropulmonary blastoma with unique cytogenetic features. (19902198)
2010
6
A rare association; pulmonary blastoma developing on extrapulmonary sequestration basis. (20395246)
2010
7
Pulmonary blastoma metastatic to the ovary. (19047906)
2009
8
Clinical, pathological and immunohistochemical features of a pulmonary blastoma in a horse. (19202177)
2009
9
Biphasic pulmonary blastoma with rapid progression. (19214452)
2009
10
Pulmonary blastoma. (17686364)
2007
11
Combined small cell carcinoma with pulmonary blastoma and adenocarcinoma: case report and clonality analysis. (17046168)
2006
12
A patient with shortness of breath and a left hilar mass. Biphasic pulmonary blastoma. (16683903)
2006
13
Survival of biphasic pulmonary blastoma. (16332433)
2006
14
Solitary brain metastasis from classic biphasic pulmonary blastoma: a case report and review of the literature. (17202827)
2006
15
A rare case of classic biphasic pulmonary blastoma. (16447486)
2005
16
Cyopathologic and histologic features of biphasic pulmonary blastoma: a case report. (15717762)
2005
17
Biphasic pulmonary blastoma presenting as endobronchial polyp with a long stalk. (15942110)
2005
18
Pulmonary blastoma. (11563261)
2001
19
Pulmonary blastoma: report of two cases. (11381509)
2001
20
Extension of a pulmonary blastoma into the left atrium. (11393507)
2001
21
Pulmonary blastoma: report of a case. (10483763)
1999
22
Pulmonary blastoma: diagnostic and therapeutic aspects. (10415291)
1999
23
Case of extra pulmonary, pleuro-pulmonary blastoma in a child: pathological and cytogenetic findings. (9142208)
1997
24
Pulmonary blastoma. (9255019)
1997
25
Resection and adjuvant chemotherapy of pulmonary blastoma. A case report. (8697409)
1996
26
p53 and MDM2 immunostaining in pulmonary blastomas and bronchogenic carcinomas. (8666362)
1996
27
Pulmonary blastoma presenting as a solitary lip metastasis: case report and review of the literature. (7552426)
1995
28
Resection and adjuvant chemotherapy of pulmonary blastoma: a case report. (8635054)
1995
29
Pulmonary blastoma in an adult presenting as a chronic loculated effusion: a diagnostic problem. (8091334)
1994
30
Pulmonary blastoma--a case and review of literature. (8613168)
1994
31
Pleuropulmonary blastoma (pulmonary blastoma of childhood): genetic link with other embryonal malignancies? (8063284)
1994
32
Pulmonary blastoma: a rare case of childhood malignancy. (1323822)
1992
33
Childhood pulmonary blastoma: a pleuropulmonary variant of the adult-type pulmonary blastoma. (1720893)
1991
34
Pulmonary blastoma with a topographic transition from blastic to more differentiated areas. An immunohistochemical assessment of its embryonic nature using stage-specific embryonic antigens. (1661048)
1991
35
Pulmonary blastoma with neuroendocrine differentiation in cell morules resembling neuroepithelial bodies. (2124206)
1990
36
Role of chemotherapy in pediatric pulmonary blastoma. (2152957)
1990
37
Pulmonary blastoma. (2176642)
1990
38
Pulmonary blastoma--report of a case. (2848950)
1988
39
Computed tomography of pulmonary blastoma in a child. (2991998)
1985
40
Pulmonary blastoma. An ultrastructural study of a case and its transplanted tumor in athymic nude mice. (7417940)
1980
41
Pulmonary blastoma. (158135)
1979
42
Cytopathologic findings in pulmonary blastoma. (295162)
1979
43
Pulmonary blastoma. (199865)
1977
44
Pulmonary blastoma: A light and electron microscopic study. (974996)
1976
45
Pulmonary blastoma: report of two cases. (1126201)
1975
46
Pulmonary blastoma. (4364385)
1974
47
Pulmonary blastoma. A case report and review of the literature. (4811746)
1974
48
Pulmonary blastoma. (4355012)
1973
49
Pulmonary blastoma with diverse mesenchymal proliferation. (5075621)
1972
50
Pulmonary blastoma with diverse metastases. (5351776)
1969

Variations for Pulmonary Blastoma

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Expression for genes affiliated with Pulmonary Blastoma

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Search GEO for disease gene expression data for Pulmonary Blastoma.

Pathways for genes affiliated with Pulmonary Blastoma

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Pathways related to Pulmonary Blastoma according to GeneCards Suite gene sharing:

(show all 21)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5KRAS, TP53
29.4EGFR, TP53
39.3EGFR, KRAS
49.3EGFR, KRAS
59.3EGFR, KRAS
6
Show member pathways
9.3EGFR, KRAS
78.9EGFR, KRAS, TP53
88.9EGFR, KRAS, TP53
9
Show member pathways
8.9EGFR, KRAS, TP53
108.9EGFR, KRAS, TP53
11
Show member pathways
8.9EGFR, KRAS, TP53
12
Show member pathways
8.9EGFR, KRAS, TP53
138.9EGFR, KRAS, TP53
148.9EGFR, KRAS, TP53
158.9EGFR, KRAS, TP53
16
Show member pathways
8.9EGFR, KRAS, TP53
178.9EGFR, KRAS, TP53
188.9EGFR, KRAS, TP53
198.9EGFR, KRAS, TP53
20
Show member pathways
8.9EGFR, KRAS, TP53
218.5DICER1, EGFR, KRAS, TP53

GO Terms for genes affiliated with Pulmonary Blastoma

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Biological processes related to Pulmonary Blastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cerebral cortex cell migrationGO:002179510.1EGFR, NKX2-1
2positive regulation of gene expressionGO:00106288.8DICER1, KRAS, NKX2-1, TP53
3Ras protein signal transductionGO:00072658.6EGFR, KRAS, TP53

Molecular functions related to Pulmonary Blastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein self-associationGO:00436219.8SYP, TP53
2identical protein bindingGO:00428028.5DES, EGFR, SYP, TP53

Sources for Pulmonary Blastoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet