Aliases & Classifications for Pulmonary Edema

MalaCards integrated aliases for Pulmonary Edema:

Name: Pulmonary Edema 12 41 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11396
ICD10 32 J81 J81.1
MeSH 41 D011654
NCIt 46 C26868
UMLS 69 C0034063

Summaries for Pulmonary Edema

MalaCards based summary : Pulmonary Edema is related to acute respiratory distress syndrome and acute mountain sickness, and has symptoms including peau d'orange, hemoptysis and edema. An important gene associated with Pulmonary Edema is ACE (Angiotensin I Converting Enzyme), and among its related pathways/superpathways are Toll-Like receptor Signaling Pathways and Allograft rejection. The drugs Sevoflurane and Magnesium Sulfate have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and kidney, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : 72 Pulmonary edema is fluid accumulation in the tissue and air spaces of the lungs. It leads to impaired... more...

Related Diseases for Pulmonary Edema

Diseases related to Pulmonary Edema via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 430)
# Related Disease Score Top Affiliating Genes
1 acute respiratory distress syndrome 32.9 CXCL8 IL1B TNF
2 acute mountain sickness 32.7 ACE EDN1 NOS3 PIK3C2A
3 adult respiratory distress syndrome 32.6 ACE CXCL8 F2 IL10 TNF
4 chronic mountain sickness 32.1 EDN1 NOS3 NPPB
5 aortic coarctation 30.1 ACE EDN1 NOS3
6 diastolic heart failure 30.1 ACE NOS3 NPPB
7 anuria 30.0 ACE PIK3C2A REN
8 cardiac tamponade 29.9 F2 NPPB REN
9 mitral valve disease 29.9 ACE IL10 NOS3
10 myocarditis 29.9 ICAM1 NPPB TNF
11 congestive heart failure 29.8 ACE EDN1 NPPB PIK3C2A REN
12 bronchiolitis obliterans 29.8 CXCL8 IL10 TNF
13 plasmodium vivax malaria 29.7 ICAM1 IL10 TNF
14 bronchiolitis 29.7 CXCL8 IL10 TNF
15 pulmonary hypertension 29.6 ACE EDN1 NOS3 NPPB REN SERPINC1
16 kidney disease 29.5 ACE EDN1 NPPB REN
17 hepatorenal syndrome 29.5 ACE EDN1 F2 REN
18 spinal cord infarction 29.5 F2 SERPINC1
19 ischemia 29.5 ACE EDN1 HMOX1 ICAM1 NOS3
20 eclampsia 29.4 EDN1 F2 SERPINC1 TNF
21 disseminated intravascular coagulation 29.4 F2 PIK3C2A SERPINC1
22 subendocardial myocardial infarction 29.3 F2 ICAM1 SERPINC1
23 apnea, obstructive sleep 29.3 CRP EDN1 REN TNF
24 hellp syndrome 29.2 EDN1 F2 SERPINC1
25 renovascular hypertension 29.2 ACE EDN1 HMOX1 NOS3 REN
26 cardiogenic shock 29.2 CRP NPPB PIK3C2A
27 mouth disease 29.1 CRP IL10 IL1B TNF
28 intracranial hypertension 29.1 F2 IL1B SERPINC1 TNF
29 pulmonary disease, chronic obstructive 29.1 CRP CXCL8 HMOX1 TNF
30 autosomal dominant polycystic kidney disease 29.1 ACE CFTR EDN1 NOS3 REN
31 meningitis 28.9 CRP CXCL8 IL10 IL1B TNF
32 pneumonia 28.8 CRP CXCL8 IL10 IL1B PIK3C2A TNF
33 diabetes mellitus 28.8 ACE CRP IL1B PIK3C2A TNF
34 acute myocardial infarction 28.6 ACE CRP EDN1 NPPB PIK3C2A SERPINC1
35 respiratory failure 28.6 ACE CRP CXCL8 EDN1 IL10 PIK3C2A
36 pulmonary embolism 28.6 CRP F2 NPPB SERPINC1
37 coronary artery anomaly 28.5 ACE CRP EDN1 NOS3 NPPB PIK3C2A
38 asthma 28.5 CFTR CXCL8 EDN1 ICAM1 IL10 IL1B
39 lung disease 28.4 CFTR CXCL8 EDN1 IL10 IL1B NPPB
40 arteriosclerosis 28.1 ACE CRP EDN1 HMOX1 ICAM1 IL10
41 sleep apnea 27.9 ACE CRP CXCL8 EDN1 ICAM1 NOS3
42 systemic lupus erythematosus 27.9 CRP F2 ICAM1 IL10 IL1B TNF
43 pre-eclampsia 27.8 EDN1 F2 HMOX1 ICAM1 IL10 NOS3
44 malaria 27.8 CRP CXCL8 EDN1 HMOX1 ICAM1 IL10
45 vascular disease 27.7 ACE CRP EDN1 HMOX1 NOS3 REN
46 heart disease 26.8 ACE CRP EDN1 F2 NOS3 NPPB
47 arteries, anomalies of 26.5 ACE CRP EDN1 F2 ICAM1 IL1B
48 myocardial infarction 26.4 ACE CRP EDN1 F2 ICAM1 IL10
49 pulmonary edema of mountaineers 12.3
50 toxic pneumonitis 11.2

Graphical network of the top 20 diseases related to Pulmonary Edema:



Diseases related to Pulmonary Edema

Symptoms & Phenotypes for Pulmonary Edema

UMLS symptoms related to Pulmonary Edema:


peau d'orange, hemoptysis, edema

GenomeRNAi Phenotypes related to Pulmonary Edema according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.92 ICAM1 IL10 IL1B ACE REN CFTR
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.92 ICAM1 IL10 IL1B ACE REN CFTR

MGI Mouse Phenotypes related to Pulmonary Edema:

43 (show all 16)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.39 HMOX1 ACE CRP EDN1 F2 IL10
2 homeostasis/metabolism MP:0005376 10.38 ACE CRP EDN1 AQP5 F2 CFTR
3 growth/size/body region MP:0005378 10.32 CFTR ACE EDN1 AQP5 F2 NOS3
4 behavior/neurological MP:0005386 10.3 F2 CFTR ACE AQP5 NOS3 IL10
5 hematopoietic system MP:0005397 10.27 CFTR ACE F2 NOS3 IL10 HMOX1
6 immune system MP:0005387 10.27 CFTR ACE CRP F2 IL10 HMOX1
7 mortality/aging MP:0010768 10.25 CFTR ACE EDN1 AQP5 F2 IL10
8 endocrine/exocrine gland MP:0005379 10.18 CFTR ACE EDN1 AQP5 IL10 HMOX1
9 digestive/alimentary MP:0005381 10.14 F2 CFTR EDN1 AQP5 NOS3 IL10
10 nervous system MP:0003631 10.06 F2 EDN1 IL10 IL1B ICAM1 REN
11 muscle MP:0005369 10.02 EDN1 AQP5 IL10 HMOX1 ICAM1 NOS3
12 liver/biliary system MP:0005370 9.98 CFTR ACE IL10 HMOX1 NOS3 SERPINC1
13 renal/urinary system MP:0005367 9.86 ACE EDN1 NOS3 HMOX1 TRPV4 SERPINC1
14 reproductive system MP:0005389 9.81 F2 CFTR ACE IL10 HMOX1 REN
15 respiratory system MP:0005388 9.56 F2 CFTR AQP5 NOS3 IL10 HMOX1
16 vision/eye MP:0005391 9.23 CFTR AQP5 ICAM1 IL10 NOS3 SERPINC1

Drugs & Therapeutics for Pulmonary Edema

Drugs for Pulmonary Edema (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 202)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
2
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 4,Phase 3 7487-88-9 24083
3
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
4
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
5
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
6
Remifentanil Approved Phase 4,Phase 2 132875-61-7 60815
7
Acetazolamide Approved, Vet_approved Phase 4 59-66-5 1986
8
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
9
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
10
Morphine Approved, Investigational Phase 4 57-27-2 5288826
11
Dobutamine Approved Phase 4,Phase 3 34368-04-2 36811
12
Benzocaine Approved, Investigational Phase 4,Phase 1,Phase 2 1994-09-7, 94-09-7 2337
13
Milrinone Approved Phase 4 78415-72-2 4197
14
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
15
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
16
Zinc Approved, Investigational Phase 4 7440-66-6 32051 23994
17
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Early Phase 1 77-92-9 311
18 tannic acid Approved, Nutraceutical Phase 4,Phase 1,Phase 2
19 Anticholesteremic Agents Phase 4
20 Antimetabolites Phase 4
21 Atorvastatin Calcium Phase 4,Phase 3 134523-03-8
22 Calcium, Dietary Phase 4,Phase 3,Phase 1,Phase 2
23 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
24 Hypolipidemic Agents Phase 4
25 Lipid Regulating Agents Phase 4
26 Anesthetics Phase 4,Phase 3,Phase 2
27 Anesthetics, General Phase 4,Phase 2
28 Anesthetics, Inhalation Phase 4
29 Central Nervous System Depressants Phase 4,Phase 3,Phase 2
30 Platelet Aggregation Inhibitors Phase 4,Phase 2
31 Pharmaceutical Solutions Phase 4,Phase 2,Phase 1
32 Vasodilator Agents Phase 4,Phase 1,Phase 2,Early Phase 1
33 Adrenergic Agents Phase 4,Phase 2,Phase 3
34 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
35 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1
36 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Analgesics Phase 4,Phase 3,Phase 2
38 Anticonvulsants Phase 4,Phase 3
39 diuretics Phase 4,Phase 3,Phase 2
40 Adrenergic Agonists Phase 4,Phase 2,Phase 3
41 Adrenergic beta-2 Receptor Agonists Phase 4,Phase 2,Phase 3
42 Adrenergic beta-Agonists Phase 4,Phase 2,Phase 3
43 Tocolytic Agents Phase 4,Phase 3,Phase 2
44 Anti-Arrhythmia Agents Phase 4,Phase 3,Phase 2
45 calcium channel blockers Phase 4,Phase 3
46 Ophthalmic Solutions Phase 4,Phase 1,Phase 2
47 Plasma-lyte 148 Phase 4,Phase 1,Phase 2
48 Anticoagulants Phase 4
49 Chelating Agents Phase 4
50 Phosphodiesterase 5 Inhibitors Phase 4,Phase 1,Phase 2,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 218)

# Name Status NCT ID Phase Drugs
1 Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn Unknown status NCT01499238 Phase 4
2 Effects of Atorvastatin Treatment on Left Ventricular Diastolic Function in Peritoneal Dialysis Patients Unknown status NCT01503671 Phase 4 Atorvastatin
3 A Comparison of Two Anaesthetic Methods of Protecting Heart Tissue During Cardiac Surgery Unknown status NCT00244283 Phase 4 Sevoflurane
4 Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure. Unknown status NCT00331656 Phase 4
5 Prevention of Contrast Nephropathy During Diagnostic Coronary Angiogram or PCI With Hydratation Based on LEVDP Unknown status NCT00584350 Phase 4
6 Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema Completed NCT00912158 Phase 4
7 CPAP Versus NPPV in ACPE Completed NCT00446498 Phase 4
8 Non-Invasive Ventilation in Pulmonary Edema Completed NCT00453947 Phase 4
9 OUT-OF-HOSPITAL CPAP STUDY Completed NCT00439075 Phase 4 standard treatment
10 Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach Completed NCT02135146 Phase 4 Plasmalyte 3ml/kg/hr group;Plasmalyte 6ml/kg/hr group
11 Randomized, Controlled Trial of Regular Sildenafil Citrate in the Prevention of Altitude Illness Completed NCT00627965 Phase 4 Sildenafil citrate;Placebo
12 Efficacy Study of Riociguat and Its Effects on Exercise Performance and Pulmonary Artery Pressure at High Altitude Completed NCT02024386 Phase 4 Riociguat
13 Acute Chest Pain Treatment and Evaluation (ACTION) Study Completed NCT00434564 Phase 4
14 Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) Completed NCT01600651 Phase 4
15 Beta-Blocker Continuation Versus Interruption in Heart Failure Worsening Completed NCT00162565 Phase 4 beta-blocker treatment
16 Electromyographic Activity of the Respiratory Muscles During Neostigmine or Sugammadex Enhanced Recovery After Neuromuscular Blockade Completed NCT02403063 Phase 4 Sugammadex;Neostigmine;Neostigmine-sugammadex
17 Effect-site Concentration of Remifentanil for Smooth Removal of the Double-lumen Endotracheal Tube Completed NCT02528825 Phase 4 Remifentanil titration
18 Acetazolamide for the Prevention of High Altitude Illness: a Comparison of Dosing Completed NCT01993667 Phase 4 Acetazolamide
19 Nebulized Heparin and Salbutamol in Mechanically Ventilated Patients With AECOPD Completed NCT03333395 Phase 4 Nebulized heparin and salbutamol;Nebulized salbutamol
20 Lumbar Plexus Block Upon the Incidence of Ischemic Cardiovascular Events in Elderly Patients With Hip Fracture Completed NCT01961895 Phase 4 Intravenous patient-controlled analgesia
21 REstrictive Versus LIbEral Fluid Therapy in Major Abdominal Surgery: RELIEF Study Completed NCT01424150 Phase 4
22 Impact of Fluid Resuscitation Therapy on Pulmonary Edema as Measured by Alveolar Fluid Clearance in Patients With Acute Respiratory Distress Syndrome (ARDS) Recruiting NCT01763853 Phase 4 4% albumin
23 Milrinone Versus Dobutamine in Critically Ill Patients Recruiting NCT03207165 Phase 4 Milrinone;Dobutamine
24 MIdazolam Versus MOrphine in Acute Pulmonary Edema (MIMO Trial) Not yet recruiting NCT02856698 Phase 4 Midazolam;Morphine
25 Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP) Not yet recruiting NCT03068741 Phase 4 Comparison 1: Prehospital Ceftriaxone;Comparison 1: Placebo;Comparison 2: Liberal fluids;Comparison 2: Conservative fluids
26 Normoglycemia and Neurological Outcome Terminated NCT01137773 Phase 4 Insulin;Conventional insulin treatment
27 Different Schemes of Magnesium Sulfate for Preeclampsia Terminated NCT02396030 Phase 4 Magnesium sulfate 50% - 1g/h;Magnesium sulfate 50% - 2g/h
28 Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF Withdrawn NCT00505791 Phase 4 Nesiritide
29 High-Dose Aldactone for Treatment of Diuretic Resistant Heart Failure Withdrawn NCT02429388 Phase 4 Spironolactone
30 Bilevel Positive Pressure Ventilation (BIPAP)in Patients With Sleep Disorders Breathing (SDB)and Congestive Heart Failure (CHF):Comparison of Two Diagnostic Methods Unknown status NCT01501734 Phase 3
31 Concomitant Tracheostomy and Lung Resection Unknown status NCT01053624 Phase 3
32 Out-of-Hospital CPAP for Severe Cardiogenic Pulmonary Edema Completed NCT00390442 Phase 3
33 CPAP Versus Bilevel Pressure Support Ventilation in Cardiogenic Pulmonary Edema Completed NCT00213681 Phase 3
34 Continuous Positive Airway Pressure for Acute Pulmonary Edema Completed NCT00554580 Phase 3
35 Non-Invasive Ventilation Versus Continuous Positive Airway Pressure in Cardiogenic Pulmonary Edema: a Multicentre Study Completed NCT00785174 Phase 3
36 Is Plasma Transfusion Beneficial Prior to Low-Risk Procedures in Hospitalized Patients With Blood Clotting Abnormalities? Completed NCT00953901 Phase 3 Fresh Frozen Plasma Transfusion
37 A Clinical Trial to Assess the Efficacy and Safety of an Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children Aged 6-35 Months Completed NCT01508247 Phase 3
38 Anti-Oxidant Supplementation for the Prevention of Acute Mountain Sickness Completed NCT00664001 Phase 3
39 Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial) Completed NCT00014989 Phase 3 magnesium sulfate
40 Non-steroidal Anti-inflammatory Affect on Kidneys in Endurance Distances Completed NCT02272725 Phase 3 Ibuprofen;Placebo
41 RenalGuard System and Contrast Media Completed NCT01098032 Phase 3 Systemic alone therapy
42 Stenting in Renal Dysfunction Caused by Atherosclerotic Renal Artery Stenosis Completed NCT00150943 Phase 3
43 Efficacy of Endovascular Catheter Cooling Combined With Cold Saline for the Treatment of Acute Myocardial Infarction Completed NCT01379261 Phase 2, Phase 3
44 Transfusion Strategy in Hematological Intensive Care Unit Recruiting NCT02461264 Phase 3 Single red blood packed cells Transfusion;Two packed red blood cells Transfusion
45 Effects of Roflumilast in Hospitalized Chronic Obstructive Pulmonary Disease( COPD) on Mortality and Re-hospitalization Active, not recruiting NCT01973998 Phase 3 Roflumilast;Placebo
46 Study of Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome (OHSS) in In Vito Fertilization Cycles and Derivation of OHSS Biomarkers Active, not recruiting NCT01535859 Phase 3 Cabergoline;Placebo
47 I.D.E.A.L.-I.C.U. (Initiation of Dialysis EArly Versus deLayed in Intensive Care Unit) Terminated NCT01682590 Phase 3
48 Hypertonic Saline vs. Mannitol for Elevated Intercranial Pressure Terminated NCT01111682 Phase 3 Mannitol;Hypertonic Saline
49 Albumin in Acute Ischemic Stroke Trial Terminated NCT00235495 Phase 3 placebo
50 Nebulized Albuterol for Congestive Heart Failure Exacerbation Withdrawn NCT01375361 Phase 2, Phase 3 Albuterol;Normal Saline

Search NIH Clinical Center for Pulmonary Edema

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: pulmonary edema

Genetic Tests for Pulmonary Edema

Anatomical Context for Pulmonary Edema

MalaCards organs/tissues related to Pulmonary Edema:

38
Lung, Heart, Kidney, Brain, Endothelial, Liver, Neutrophil

Publications for Pulmonary Edema

Articles related to Pulmonary Edema:

(show top 50) (show all 826)
# Title Authors Year
1
Predicting cardiogenic pulmonary edema in heart failure patients by using an N-terminal pro-b-type natriuretic peptide (NT-pro BNP) -based score. ( 29408167 )
2018
2
Transcriptomic profiling reveals gene expression kinetics in patients with hypoxia and high altitude pulmonary edema. ( 29366758 )
2018
3
Refractory Pulmonary Edema and Upper Body Hypoxemia During Veno-Arterial Extracorporeal Membrane Oxygenation-A Case for Atrial Septostomy. ( 29344963 )
2018
4
HMOX1 Promoter Microsatellite Polymorphism and High Altitude Pulmonary Edema in Han Chinese Men. ( 29398188 )
2018
5
Regional Negative Pressure Pulmonary Edema with Pulmonary Thromboembolism. ( 29434139 )
2018
6
Negative pressure pulmonary edema. ( 29441178 )
2018
7
Neurogenic Pulmonary Edema and Stunned Myocardium in a Patient With Meningioma: A Heart-Brain Cross Talk. ( 29432276 )
2018
8
Sensitivity and specificity of ultrasound for the diagnosis of acute pulmonary edema: a systematic review and meta-analysis. ( 29400365 )
2018
9
Upfront triple combination therapy-induced pulmonary edema in a case of pulmonary arterial hypertension associated with Sjogren's syndrome. ( 29276674 )
2018
10
The Key Roles of Negative Pressure Breathing and Exercise in the Development of Interstitial Pulmonary Edema in Professional Male SCUBA Divers. ( 29299780 )
2018
11
Elevated Vasodilatory Cyclases and Shorter Telomere Length Contribute to High-Altitude Pulmonary Edema. ( 29443612 )
2018
12
New insights into the mechanisms of pulmonary edema in acute lung injury. ( 29430449 )
2018
13
Identification of Pulmonary Edema in Forensic Autopsy Cases of Sudden Cardiac Death Using Fourier Transform Infrared Microspectroscopy: A Pilot Study. ( 29364657 )
2018
14
The need for systematic diagnosis of exercise-induced respiratory syndromes: the example of swimming-induced pulmonary edema. ( 28820003 )
2017
15
A systematic review of diagnostic methods to differentiate acute lung injury/acute respiratory distress syndrome from cardiogenic pulmonary edema. ( 28841896 )
2017
16
Neurogenic Pulmonary Edema Complicating ECT. ( 29166318 )
2017
17
A Case of MDMA-Associated Cerebral and Pulmonary Edema Requiring ECMO. ( 29270322 )
2017
18
Targeting resolution of pulmonary edema in primary graft dysfunction after lung transplantation: Is inhaled AP301 the answer? ( 29198870 )
2017
19
High peak PaO2 values are associated with adverse outcome in critically ill patients treated with non-invasive ventilation for acute cardogenic pulmonary edema and pneumonia. ( 28884567 )
2017
20
A critical appraisal of the morphine in the acute pulmonary edema: real or real uncertain? ( 28839968 )
2017
21
Non-invasive ventilation in acute cardiogenic pulmonary edema: how to do it. ( 28952011 )
2017
22
Assessment of Pulmonary Edema: Principles and Practice. ( 29174750 )
2017
23
Unilateral High-Altitude Pulmonary Edema. ( 28837778 )
2017
24
Burden and correlates of readmissions related to pulmonary edema in US hemodialysis patients: a cohort study. ( 29294094 )
2017
25
Cystic Fibrosis Transmembrane Conductance Regulator Potentiation as a Therapeutic Strategy for Pulmonary Edema: A Proof-of-Concept Study in Pigs. ( 28953499 )
2017
26
A Morphological and Quantitative Analysis of Lung CT Scan in Patients With Acute Respiratory Distress Syndrome and in Cardiogenic Pulmonary Edema. ( 29161936 )
2017
27
Reentry High Altitude Pulmonary Edema in the Himalayas. ( 28910201 )
2017
28
Susceptibility To High Altitude Pulmonary Edema Is Associated With A More Uniform Distribution Of Regional Specific Ventilation. ( 28057815 )
2017
29
Swimming-induced pulmonary edema in a tropical climate: a case report. ( 28779587 )
2017
30
Management of Neurogenic Pulmonary Edema and Differential Hypoxemia in an Adult Supported on Venoarterial Extracorporeal Membrane Oxygenation. ( 28764986 )
2017
31
HMOX1 Promoter Microsatellite Polymorphism Is Not Associated With High Altitude Pulmonary Edema in Han Chinese. ( 28257713 )
2017
32
Diagnosis of Swimming Induced Pulmonary Edema-A Review. ( 28912730 )
2017
33
Severe pulmonary edema following hyperbaric oxygen therapy for acute carbon monoxide poisoning: a case report and clinical experience. ( 28779586 )
2017
34
Inhaled AP301 for treatment of pulmonary edema in mechanically ventilated patients with acute respiratory distress syndrome: a phase IIa randomized placebo-controlled trial. ( 28750677 )
2017
35
Electron Microscopy Observation of Human Pulmonary Ultrastructure in Two Patients with High-Altitude Pulmonary Edema. ( 28876136 )
2017
36
Clinical Features of Patients with Diffuse Alveolar Hemorrhage due to Negative-Pressure Pulmonary Edema. ( 28455784 )
2017
37
Pulmonary Edema After Near Hanging: An Insight. ( 28886777 )
2017
38
OSA and Prognosis After Acute Cardiogenic Pulmonary Edema: The OSA-CARE Study. ( 28823814 )
2017
39
Recurrence of non-cardiogenic pulmonary edema and sustained hypotension shock in cystic pheochromocytoma. ( 28471119 )
2017
40
Serial Sonographic Assessment of Pulmonary Edema in Patients With Hypertensive Acute Heart Failure. ( 28758715 )
2017
41
High-Altitude Pulmonary Edema in Mountain Community Residents. ( 28846035 )
2017
42
Acute pulmonary edema in patients with reduced left ventricular ejection fraction is associated with concentric left ventricular geometry. ( 28770454 )
2017
43
Pulmonary edema following central nervous system lesions induced by a non- mouse-adapted EV71 strain in neonatal BALB/c mice. ( 29282065 )
2017
44
Reply: Unilateral Pulmonary Edema after Visiting High Altitude. ( 28837781 )
2017
45
Acute pulmonary edema caused by takotsubo cardiomyopathy in a pregnant woman undergoing transvaginal cervical cerclage: A case report. ( 28072695 )
2017
46
Therapeutic efficacy of phentolamine in the management of severe hand, foot and mouth disease combined with pulmonary edema. ( 28413485 )
2017
47
16-Year-Old Female Near Hanging With Negative Pressure Pulmonary Edema. ( 28089063 )
2017
48
Managing High-Altitude Pulmonary Edema with Oxygen Alone: Results of a Randomized Controlled Trial. ( 27906598 )
2016
49
Pulmonary Edema and Hypoxic Respiratory Failure. ( 27490597 )
2016
50
Efficacy of pimobendan on survival and reoccurrence of pulmonary edema in canine congestive heart failure. ( 27644192 )
2016

Variations for Pulmonary Edema

Expression for Pulmonary Edema

Search GEO for disease gene expression data for Pulmonary Edema.

Pathways for Pulmonary Edema

Pathways related to Pulmonary Edema according to GeneCards Suite gene sharing:

(show all 39)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.93 CFTR CXCL8 EDN1 HMOX1 IL1B TNF
2
Show member pathways
12.8 CXCL8 ICAM1 IL10 IL1B TNF
3
Show member pathways
12.55 F2 IL10 IL1B NOS3 TNF
4
Show member pathways
12.5 ACE CXCL8 IL10 IL1B TNF
5
Show member pathways
12.43 CFTR CXCL8 HMOX1 NOS3
6
Show member pathways
12.28 CFTR CXCL8 IL1B TNF
7
Show member pathways
12.26 CRP F2 ICAM1 IL1B TNF
8
Show member pathways
12.15 CFTR CXCL8 IL1B TNF
9 12.14 CXCL8 IL10 IL1B TNF
10
Show member pathways
12.12 CXCL8 IL10 IL1B TNF
11 11.97 CXCL8 ICAM1 IL1B TNF
12 11.91 EDN1 ICAM1 IL1B TNF
13 11.84 CXCL8 IL10 IL1B TNF
14 11.83 CXCL8 ICAM1 IL1B TNF
15
Show member pathways
11.82 CFTR CXCL8 ICAM1
16 11.79 HMOX1 NOS3 REN
17 11.79 CXCL8 ICAM1 IL1B TNF
18
Show member pathways
11.74 ACE NOS3 REN
19 11.74 IL10 IL1B TNF
20 11.7 IL10 IL1B TNF
21 11.69 CXCL8 IL10 IL1B TNF
22 11.69 CXCL8 HMOX1 ICAM1 IL10 IL1B TNF
23 11.64 ICAM1 IL10 TNF
24
Show member pathways
11.58 CXCL8 ICAM1 IL1B TNF
25 11.57 CXCL8 EDN1 HMOX1 IL1B TNF
26 11.55 CXCL8 IL1B TNF
27 11.43 CXCL8 EDN1 ICAM1 IL1B NOS3 TNF
28 11.41 CXCL8 ICAM1 IL10 IL1B TNF
29 11.34 CXCL8 ICAM1 IL10 IL1B TNF
30 11.31 CXCL8 HMOX1 NOS3
31 11.31 EDN1 HMOX1 ICAM1 IL1B NOS3 TNF
32 11.3 ICAM1 IL10 IL1B TNF
33 11.28 HMOX1 IL10 IL1B TNF
34 11.24 IL10 IL1B TNF
35 11.17 CXCL8 IL10 IL1B TNF
36 11.14 F2 ICAM1 IL1B
37 10.98 CRP CXCL8 HMOX1 TNF
38 10.87 ICAM1 IL1B TNF
39 10.79 CFTR NOS3

GO Terms for Pulmonary Edema

Cellular components related to Pulmonary Edema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 ACE CRP CXCL8 EDN1 F2 IL10
2 external side of plasma membrane GO:0009897 9.46 ACE F2 ICAM1 TNF
3 extracellular space GO:0005615 9.44 ACE CRP CXCL8 EDN1 F2 HMOX1

Biological processes related to Pulmonary Edema according to GeneCards Suite gene sharing:

(show all 44)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.97 CRP CXCL8 IL10 IL1B TNF
2 leukocyte migration GO:0050900 9.95 F2 ICAM1 IL1B TNF
3 response to organic substance GO:0010033 9.87 IL10 REN TNF
4 cellular response to interleukin-1 GO:0071347 9.85 CXCL8 EDN1 ICAM1
5 positive regulation of JNK cascade GO:0046330 9.85 IL1B TNF TRPV4
6 positive regulation of angiogenesis GO:0045766 9.85 CXCL8 HMOX1 IL1B NOS3
7 response to insulin GO:0032868 9.83 ICAM1 IL10 TRPV4
8 cellular response to drug GO:0035690 9.83 EDN1 IL1B REN
9 neutrophil chemotaxis GO:0030593 9.8 CXCL8 EDN1 IL1B
10 cellular response to lipopolysaccharide GO:0071222 9.8 CXCL8 ICAM1 IL10 TNF
11 positive regulation of smooth muscle cell proliferation GO:0048661 9.78 EDN1 HMOX1 TNF
12 response to lipopolysaccharide GO:0032496 9.77 EDN1 ICAM1 IL10 IL1B REN
13 positive regulation of DNA binding transcription factor activity GO:0051091 9.76 EDN1 IL10 IL1B TNF
14 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 9.71 HMOX1 ICAM1 NOS3
15 positive regulation of renal sodium excretion GO:0035815 9.69 EDN1 NPPB
16 positive regulation of urine volume GO:0035810 9.69 EDN1 NPPB
17 negative regulation of calcium ion transport GO:0051926 9.68 ICAM1 NOS3
18 response to molecule of bacterial origin GO:0002237 9.68 CXCL8 IL10
19 angiotensin maturation GO:0002003 9.68 ACE REN
20 positive regulation of monocyte chemotactic protein-1 production GO:0071639 9.68 IL1B TRPV4
21 negative regulation of lipid storage GO:0010888 9.67 CRP TNF
22 body fluid secretion GO:0007589 9.66 EDN1 NPPB
23 negative regulation of platelet activation GO:0010544 9.66 F2 NOS3
24 lipopolysaccharide-mediated signaling pathway GO:0031663 9.65 IL1B NOS3 TNF
25 acute inflammatory response to antigenic stimulus GO:0002438 9.64 ICAM1 SERPINC1
26 endothelial cell apoptotic process GO:0072577 9.64 IL10 TNF
27 multicellular organismal water homeostasis GO:0050891 9.63 CFTR TRPV4
28 positive regulation of prostaglandin secretion GO:0032308 9.62 EDN1 IL1B
29 regulation of establishment of endothelial barrier GO:1903140 9.61 IL1B TNF
30 regulation of systemic arterial blood pressure by endothelin GO:0003100 9.6 EDN1 NOS3
31 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.59 ICAM1 TNF
32 negative regulation of cytokine secretion involved in immune response GO:0002740 9.58 IL10 TNF
33 regulation of blood vessel size GO:0050880 9.58 EDN1 NOS3 NPPB
34 positive regulation of fever generation GO:0031622 9.57 IL1B TNF
35 sequestering of triglyceride GO:0030730 9.56 IL1B TNF
36 positive regulation of nitric oxide biosynthetic process GO:0045429 9.56 EDN1 ICAM1 IL1B TNF
37 receptor biosynthetic process GO:0032800 9.52 IL10 TNF
38 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.51 IL1B TNF
39 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.5 IL10 IL1B TNF
40 regulation of receptor activity GO:0010469 9.5 CXCL8 EDN1 F2 IL10 IL1B NPPB
41 smooth muscle hyperplasia GO:0014806 9.43 HMOX1 NOS3
42 positive regulation of chemokine biosynthetic process GO:0045080 9.33 HMOX1 IL1B TNF
43 regulation of blood pressure GO:0008217 9.1 ACE EDN1 HMOX1 NOS3 NPPB REN
44 negative regulation of cell proliferation GO:0008285 10.02 CXCL8 HMOX1 IL10 IL1B NOS3

Molecular functions related to Pulmonary Edema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.86 AQP5 CFTR CRP CXCL8 EDN1 F2
2 cytokine activity GO:0005125 9.02 CXCL8 EDN1 IL10 IL1B TNF

Sources for Pulmonary Edema

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