MCID: PLM010
MIFTS: 49

Pulmonary Edema malady

Respiratory diseases category
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Summaries for Pulmonary Edema

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Wikipedia:65 Pulmonary edema (American English), or oedema (British English; both words from the Greek ??????), is... more...

MalaCards based summary: Pulmonary Edema is related to hypertension and pulmonary hypertension. An important gene associated with Pulmonary Edema is NPPB (natriuretic peptide B), and among its related pathways are Pertussis and FOXA1 transcription factor network. The drugs bumetanide and ethacrynate sodium and the compounds imidapril and aldosterone have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and endothelial.

Aliases & Classifications for Pulmonary Edema

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Pulmonary Edema, Aliases & Descriptions:

Name: Pulmonary Edema 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


External Ids:

Disease Ontology8 DOID:11396
MeSH34 D011654
NCIt39 C26868

Related Diseases for Pulmonary Edema

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Diseases related to Pulmonary Edema via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 151)
idRelated DiseaseScoreTop Affiliating Genes
1hypertension30.9CYBA, CYP11B2, NPPB
2pulmonary hypertension30.9ELANE, NPPB
3congestive heart failure30.6NPPB, CYP11B2
4myocardial infarction30.6NPPB, CYP11B2, CYBA
5chronic obstructive pulmonary disease30.3NPPB, ELANE
6septic shock30.1NPPB, ELANE
7sepsis30.1NPPB, ELANE, SMPD1
8pneumothorax10.6
9spontaneous pneumothorax10.5
10endotheliitis10.5
11aneurysm10.4
12adult respiratory distress syndrome10.4
13epiglottitis10.4
14acute mountain sickness10.4
15hypoxia10.4
16pulmonary fibrosis10.4ELANE
17pulmonary edema of mountaineers10.3
18acute myocardial infarction10.3
19rheumatic fever10.3
20toxic pneumonitis10.3
21pneumonia10.3
22cor triatriatum10.3
23multiple sclerosis10.2
24spinal cord injury10.2
25croup10.2
26ovarian hyperstimulation syndrome10.2
27hypercalcemia10.2
28bronchopneumonia10.2
29cerebritis10.2
30mediastinitis10.2
31aspergillosis10.2SFTPA2, ELANE
32kawasaki disease10.2NPPB, ELANE
33cork-handlers' disease10.2ELANE, SFTPA2
34asthma10.1
35diabetes mellitus10.1
36malaria10.1
37anuria10.1
38hantavirus pulmonary syndrome10.1
39primary pulmonary hypertension10.1
40cardiac tamponade10.1
41status epilepticus10.1
42hellp syndrome10.1
43obstructive sleep apnea10.1
44peripartum cardiomyopathy10.1
45hypoglycemia10.1
46intracranial aneurysm10.1
47aortic aneurysm10.1
48disseminated intravascular coagulation10.1
49encephalitis10.1
50hyperparathyroidism10.1

Graphical network of the top 20 diseases related to Pulmonary Edema:



Diseases related to pulmonary edema

Symptoms for Pulmonary Edema

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Drugs & Therapeutics for Pulmonary Edema

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Drug clinical trials:

Search ClinicalTrials for Pulmonary Edema

Search NIH Clinical Center for Pulmonary Edema

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Pulmonary Edema

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Anatomical Context for Pulmonary Edema

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MalaCards organs/tissues related to Pulmonary Edema:

32
Lung, Heart, Endothelial, Brain, Kidney, Spinal cord, Neutrophil, Bronchial epithelium, Lymph node, Liver

Animal Models for Pulmonary Edema or affiliated genes

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Publications for Pulmonary Edema

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Articles related to Pulmonary Edema:

(show top 50)    (show all 658)
idTitleAuthorsYear
1
Neurogenic pulmonary edema in pediatric multiple sclerosis: patient report and summary of cases. (25160550)
2014
2
Atrial natriuretic peptide attenuates agonist-induced pulmonary edema in mice with targeted disruption of the gene for natriuretic peptide receptor-A. (23195629)
2013
3
Paramedic identification of acute pulmonary edema in a metropolitan ambulance service. (23484502)
2013
4
Negative pressure pulmonary edema related to bronchospasm during anesthetic recovery. (23904949)
2013
5
High-altitude pulmonary edema: diagnosis, prevention, and treatment. (23478563)
2013
6
Rupture of a Noncoronary Sinus of Valsalva Aneurysm into the Left Atrium: A Rare Cause of Acute Pulmonary Edema. (24006888)
2013
7
Reexpansion pulmonary edema in children. (24142327)
2013
8
Noncardiogenic pulmonary edema. (23532787)
2012
9
Preoperative neurogenic pulmonary edema: A dilemma for decision making. (22557750)
2012
10
Subarachnoid hemorrhage complicated with neurogenic pulmonary edema and takotsubo-like cardiomyopathy. (22362283)
2012
11
Noninvasive ventilation in pulmonary edema complicating acute myocardial infarction. (22850288)
2012
12
Hemoptysis and pulmonary edema in a scuba diver using diclofenac. (22354373)
2012
13
An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure. (23136043)
2012
14
Protection against LPS-induced pulmonary edema through the attenuation of protein tyrosine phosphatase-1B oxidation. (22180868)
2012
15
Non-cardiogenic mechanisms for the pulmonary edema induced by scorpion venom. (22521599)
2012
16
Recurrent pulmonary edema secondary to elongated soft palate in a cat. (22398461)
2012
17
Acute pulmonary edema and airway hemorrhage in a goat during sevoflurane anesthesia. (21274835)
2011
18
Effects of ischemic acute kidney injury on lung water balance: nephrogenic pulmonary edema? (21660235)
2011
19
Involvement of nitric oxide pathways in neurogenic pulmonary edema induced by vagotomy. (21808876)
2011
20
Diagnostic utility of C-reactive protein combined with brain natriuretic peptide in acute pulmonary edema: a cross sectional study. (21696613)
2011
21
Interest of chest ultrasonography in the detection of exercise-induced pulmonary edema. (20960679)
2010
22
Long-term survival and quality of life after transfusion-associated pulmonary edema in critically ill medical patients. (19837827)
2010
23
Endothelial nitric oxide synthase gene polymorphisms associated with susceptibility to high altitude pulmonary edema in Chinese railway construction workers at Qinghai-Tibet over 4 500 meters above sea level. (21232181)
2010
24
Inhibition of secretory phospholipase A2 activity attenuates acute cardiogenic pulmonary edema induced by isoproterenol infusion in mice after myocardial infarction. (20625313)
2010
25
Effectiveness of human atrial natriuretic peptide supplementation in pulmonary edema patients using the pulse contour cardiac output system. (20376887)
2010
26
Hybrid renal replacement treatment in acute pulmonary edema with acute kidney injury following multiple wasp stings: a report of 3 cases. (20689272)
2010
27
Prognostic indicators in patients presenting with acute cardiogenic pulmonary edema treated with CPAP: it's not the acid that matters, it's back to basics. (21138600)
2010
28
Unilateral re-expansion pulmonary edema: a rare complication following one-lung ventilation for minimal invasive mitral valve reconstruction. (19549047)
2009
29
What is your diagnosis? Cardiogenic pulmonary edema. (19284334)
2009
30
The role of nitric oxide in the development of neurogenic pulmonary edema in spinal cord-injured rats: the effect of preventive interventions. (19675280)
2009
31
Radiographic features of cardiogenic pulmonary edema in dogs with mitral regurgitation: 61 cases (1998-2007). (19878003)
2009
32
Negative pressure pulmonary edema complicating an electrophysiological study. (19446350)
2009
33
Hyperacute pulmonary edema complicating rituximab infusion. (19237066)
2009
34
Re-expansion pulmonary edema following treatment of spontaneous pneumothorax during oral surgery. (19462219)
2009
35
Alcohol abuse enhances pulmonary edema in acute respiratory distress syndrome. (19572988)
2009
36
Tako-tsubo cardiomyopathy presenting with acute pulmonary edema. (19187409)
2009
37
Noninvasive positive pressure ventilation: effect on mortality in acute cardiogenic pulmonary edema: a pragmatic meta-analysis. (19694215)
2009
38
Pulmonary edema after extensive radiofrequency ablation for atrial fibrillation. (18179523)
2008
39
Excessive gas exchange impairment during exercise in a subject with a history of bronchopulmonary dysplasia and high altitude pulmonary edema. (17394419)
2007
40
Ipsilateral reexpansion pulmonary edema after drainage of a spontaneous pneumothorax: a case report. (17903268)
2007
41
Diagnostic and prognostic utility of brain natriuretic Peptide in subjects admitted to the ICU with hypoxic respiratory failure due to noncardiogenic and cardiogenic pulmonary edema. (17426196)
2007
42
Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice. (17435079)
2007
43
B-type natriuretic peptide in the assessment of acute lung injury and cardiogenic pulmonary edema. (16691132)
2006
44
Mechanism of fulminant pulmonary edema caused by enterovirus 71. (15227628)
2004
45
PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide. (14704790)
2004
46
Research on the relationship between expression of VEGF and high altitude pulmonary edema]. (11236633)
2000
47
Hepatocyte growth factor and keratinocyte growth factor in the pulmonary edema fluid of patients with acute lung injury. Biologic and clinical significance. (9700111)
1998
48
Neuropeptides in pulmonary edema fluid of adult respiratory distress syndrome. (1428125)
1992
49
Pulmonary edema after ritodrine infusion for premature labor in a patient with mitral valve disease. (7211242)
1981
50
Capillary leak syndrome with pulmonary edema. (5035983)
1972

Variations for Pulmonary Edema

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Expression for genes affiliated with Pulmonary Edema

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Expression patterns in normal tissues for genes affiliated with Pulmonary Edema

Search GEO for disease gene expression data for Pulmonary Edema.

Pathways for genes affiliated with Pulmonary Edema

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Pathways related to Pulmonary Edema according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6SFTPA2, SFTPA1
2
Show member pathways
FOXA transcription factor networks37
9.6SFTPA2, SFTPA1
39.0SFTPA2, SFTPA1, CYBA

Compounds for genes affiliated with Pulmonary Edema

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Compounds related to Pulmonary Edema according to GeneCards/GeneDecks:

(show all 36)
idCompoundScoreTop Affiliating Genes
1imidapril44 5011.1CYP11B2, NPPB
2aldosterone28 24 1112.1NPPB, CYP11B2
3atenolol44 50 28 24 1114.1NPPB, CYP11B2
4candesartan44 50 28 1113.1NPPB, CYP11B2
5spironolactone44 61 28 50 1114.1CYP11B2, NPPB
6ang ii4410.1CYP11B2, NPPB
7losartan44 50 28 1113.0NPPB, CYP11B2
8phosphoramidon44 1111.0NPPB, ELANE
9nitroglycerin44 1111.0NPPB, ELANE
10captopril44 61 50 28 1113.9ELANE, NPPB
11haloperidol44 50 28 2 1113.9NPPB, CYP11B2
12pentoxifylline44 1110.9ELANE, NPPB
13phenylephrine44 28 24 1112.9NPPB, ELANE
14aprotinin44 1110.9ELANE, NPPB
15p002449.8CYP11B2, NPPB
16sodium nitroprusside449.8ELANE, NPPB
17hocl449.7ELANE, CYBA
18n-formylmethionyl-leucylphenylalanine449.6ELANE, CYBA
19norepinephrine44 24 1111.6NPPB, ELANE, CYP11B2
20leupeptin449.5ELANE, SMPD1
21hydrocortisone44 2 61 1112.4ELANE, CYP11B2
22testosterone44 61 24 1112.4CYP11B2, ELANE, NPPB
23dexamethasone44 50 28 1112.1NPPB, CYP11B2, CYBA
24pge2449.1SMPD1, ELANE, NPPB
25doxorubicin44 50 1111.0CYBA, SMPD1, NPPB
26arginine448.9NPPB, SMPD1, CYP11B2
27cholesterol44 28 24 1111.8SMPD1, CYP11B2, CYBA
28h2o2448.7ELANE, SMPD1, CYBA
29oligonucleotide448.7SMPD1, CYP11B2, CYBA
30nitric oxide44 24 1110.7CYBA, CYP11B2, SMPD1, NPPB
31glucose448.6CYBA, CYP11B2, SMPD1, NPPB
32Water248.6CYP11B2, SMPD1, NPPB
33lipid448.6NPPB, SMPD1, CYP11B2, CYBA
34superoxide44 249.6CYBA, SMPD1, ELANE, NPPB
35oxygen44 249.2NPPB, ELANE, SMPD1, CYP11B2, CYBA
36calcium44 50 24 1110.8CYBA, CYP11B2, SFTPA1, SFTPA2, SMPD1, NPPB

GO Terms for genes affiliated with Pulmonary Edema

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Cellular components related to Pulmonary Edema according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1collagenGO:0055819.5SFTPA2, SFTPA1
2secretory granuleGO:0301419.0CYBA, ELANE
3extracellular regionGO:0055768.7NPPB, ELANE, SFTPA2, SFTPA1
4extracellular spaceGO:0056158.4NPPB, SMPD1, SFTPA2, SFTPA1

Biological processes related to Pulmonary Edema according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1respiratory gaseous exchangeGO:0075859.6SFTPA2, SFTPA1

Molecular functions related to Pulmonary Edema according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1carbohydrate bindingGO:0302469.6SFTPA2, SFTPA1
2heme bindingGO:0200379.1CYP11B2, CYBA

Products for genes affiliated with Pulmonary Edema

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Sources for Pulmonary Edema

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet