MCID: PLM033
MIFTS: 60

Pulmonary Embolism malady

Categories: Cardiovascular diseases, Respiratory diseases

Aliases & Classifications for Pulmonary Embolism

Summaries for Pulmonary Embolism

MedlinePlus : 41 a pulmonary embolism is a sudden blockage in a lung artery. the cause is usually a blood clot in the leg called a deep vein thrombosis that breaks loose and travels through the bloodstream to the lung. pulmonary embolism is a serious condition that can cause permanent damage to the affected lung low oxygen levels in your blood damage to other organs in your body from not getting enough oxygen if a clot is large, or if there are many clots, pulmonary embolism can cause death. half the people who have pulmonary embolism have no symptoms. if you do have symptoms, they can include shortness of breath, chest pain or coughing up blood. symptoms of a blood clot include warmth, swelling, pain, tenderness and redness of the leg. the goal of treatment is to break up clots and help keep other clots from forming. nih: national heart, lung, and blood institute

MalaCards based summary : Pulmonary Embolism, also known as pulmonary artery embolism, is related to thrombophilia due to activated protein c resistance and artery disease, and has symptoms including coughing, hemoptysis and snoring. An important gene associated with Pulmonary Embolism is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Heparin and Zinc have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and brain, and related phenotypes are cardiovascular system and homeostasis/metabolism

Disease Ontology : 12 An artery disease characterized by a blockage of the main artery of the lung or one of its branches by a substance that has travelled from elsewhere in the body, e.g. a blood clot.

CDC : 3 Learn more about travel and blood clots

Wikipedia : 71 Pulmonary embolism (PE) is a blockage of an artery in the lungs by a substance that has traveled from... more...

Related Diseases for Pulmonary Embolism

Diseases related to Pulmonary Embolism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 418)
id Related Disease Score Top Affiliating Genes
1 thrombophilia due to activated protein c resistance 31.1 APOH F2 F3 F5 MTHFR SERPINC1
2 artery disease 29.4 CRP F2 F3
3 lung cancer 29.4 APOH F5 MTHFR
4 lymphoblastic lymphoma 29.0 ALB F2 SERPINC1 SERPINF2
5 myotonic dystrophy 28.8 F10 F2 F3 F5 F9
6 budd-chiari syndrome 28.4 APOH CRP F2 F3 F5 MTHFR
7 myocardial infarction 28.0 ALB CRP F10 F2 F3 F5
8 pulmonary embolism and infarction 12.1
9 puerperal pulmonary embolism 12.1
10 chronic thromboembolic pulmonary hypertension 11.5
11 protein c deficiency 11.2
12 respiratory failure 11.2
13 hereditary antithrombin deficiency 11.0
14 prothrombin-related thrombophilia 11.0
15 polycythemia vera, somatic 11.0
16 factor v leiden thrombophilia 10.9
17 thrombophilia due to thrombin defect 10.9
18 pleural disease 10.9
19 thrombosis 10.5
20 multiple familial trichoepithelioma 10.3 F5 MTHFR
21 congenital insensitivity to pain with severe intellectual disability 10.3 F2 F5
22 nondystrophic myotonia 10.3 ALB F2
23 hemarthrosis 10.3 F2 F3
24 stroke, ischemic 10.3 F2 F3 F5
25 scn8a-related epilepsy with encephalopathy 10.3 F2 MTHFR
26 photosensitive epilepsy 10.3 F2 F5 MTHFR
27 low anorectal malformation 10.3 F2 F3 F5
28 absence of innominate vein 10.3 F5 MTHFR SERPINE1
29 atrophic nonflaccid tympanic membrane 10.2 F2 F3 F5
30 aminoaciduria 10.2 F5 MTHFR SERPINE1
31 acute infection of pinna 10.2 CRP F2
32 med13l syndrome 10.2 APOH F5
33 porphyria 10.2 F2 MTHFR
34 myosclerosis, congenital 10.2 F5 MTHFR SERPINC1
35 mixed epithelial tumor of ovary 10.2 F2 MTHFR SERPINC1
36 stt3a-cdg and stt3b-cdg 10.2 F5 SERPINC1 SERPINE1
37 brazilian hemorrhagic fever 10.2 PLAT SERPINC1 SERPINE1
38 neutropenia 10.2 MTHFR SERPINE1
39 vulvitis 10.2 F2 F3 SERPINE1
40 alpha-2-plasmin inhibitor deficiency 10.2 F2 MTHFR SERPINC1
41 childhood type dermatomyositis 10.2 F2 F5 MTHFR
42 periosteal chondrosarcoma 10.2 F2 SERPINC1 SERPINE1
43 chronic inflammatory demyelinating polyneuritis 10.2 ALB F2 F3
44 mental retardation hypotonia skin hyperpigmentation 10.2 F5 SERPINC1 SERPINE1
45 achard thiers syndrome 10.2 APOH F5
46 unilateral multicystic dysplastic kidney 10.2 CRP NPPB PLAT
47 sertoli cell tumor 10.2 F3 SERPINC1
48 citrulline transport defect 10.2 CRP F2 NPPB
49 isolated brachycephaly 10.2 TNNI3 TNNT2
50 cerebral calcifications opalescent teeth phosphaturia 10.2 PLAT SERPINE1

Graphical network of the top 20 diseases related to Pulmonary Embolism:



Diseases related to Pulmonary Embolism

Symptoms & Phenotypes for Pulmonary Embolism

UMLS symptoms related to Pulmonary Embolism:


coughing, hemoptysis, snoring

MGI Mouse Phenotypes related to Pulmonary Embolism:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.93 CRP F10 F2 F3 F5 F9
2 homeostasis/metabolism MP:0005376 9.83 SERPINE1 SERPINF2 TNNT2 ALB APOH CRP
3 mortality/aging MP:0010768 9.47 TNNT2 ALB APOH F10 F2 F3

Drugs & Therapeutics for Pulmonary Embolism

Drugs for Pulmonary Embolism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 405)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9005-49-6 772 46507594
2
Zinc Approved Phase 4 7440-66-6 32051 23994
3
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Early Phase 1 50-78-2 2244
4
Furosemide Approved, Vet_approved Phase 4,Phase 3 54-31-9 3440
5
Warfarin Approved Phase 4,Phase 3,Phase 2,Phase 1 81-81-2 6691 54678486
6
Tinzaparin Approved Phase 4,Phase 2,Phase 3 9005-49-6, 9041-08-1 25244225
7
Tranylcypromine Approved Phase 4 155-09-9 441233
8
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
9
Phenprocoumon Approved Phase 4,Phase 3 435-97-2 9908 54680692
10
Rivaroxaban Approved Phase 4,Phase 3,Phase 2,Phase 1 366789-02-8
11 Nadroparin Approved Phase 4,Phase 2,Phase 3 9041-08-1
12
Benzocaine Approved Phase 4,Phase 3 1994-09-7, 94-09-7 2337
13
Dalteparin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9041-08-1
14
Nitric Oxide Approved Phase 4,Phase 2,Phase 3,Phase 1 10102-43-9 145068
15
Acetaminophen Approved Phase 4,Phase 2,Phase 1 103-90-2 1983
16
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754 657311
17
Drospirenone Approved Phase 4 67392-87-4 68873
18
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613 2171
19
Acenocoumarol Approved Phase 4,Phase 3 152-72-7 9052 54676537
20
Apixaban Approved Phase 4,Phase 3,Phase 2,Phase 1 503612-47-3 10182969
21
Desirudin Approved Phase 4,Phase 2,Phase 3 120993-53-5
22 Edoxaban Approved Phase 4,Phase 3,Phase 2 480449-70-5
23
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
24
Epoprostenol Approved Phase 4 61849-14-7, 35121-78-9 5280427 5282411
25
Streptokinase Approved Phase 4 9002-01-1
26
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
27
Pancrelipase Approved Phase 4,Phase 3 53608-75-6
28
Xylometazoline Approved Phase 4 526-36-3 5709
29
Verapamil Approved Phase 4 52-53-9 2520
30
Fibrinolysin Approved Phase 4,Phase 3,Phase 2 9004-09-5
31
Polidocanol Approved Phase 4 9002-92-0
32
Menadione Approved, Nutraceutical Phase 4,Phase 2,Phase 3 58-27-5 4055
33 tannic acid Approved, Nutraceutical Phase 4,Phase 3
34
Phytonadione Approved, Nutraceutical Phase 4,Phase 2,Phase 3 84-80-0 4812 5284607
35
Butyric Acid Experimental Phase 4 107-92-6 264
36 fondaparinux Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
37 Dabigatran Phase 4,Phase 3,Phase 2
38 calcium heparin Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
39 insulin Phase 4,Early Phase 1
40 Thrombin Phase 4,Phase 3,Phase 2
41 Analgesics Phase 4,Phase 2,Phase 3,Early Phase 1
42 diuretics Phase 4,Phase 3
43
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
44 Serine Proteinase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
45 Coagulants Phase 4,Phase 3,Phase 2
46 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Cyclooxygenase Inhibitors Phase 4,Phase 2,Phase 3,Early Phase 1
48 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
49 Thromboplastin Phase 4,Phase 3,Phase 2
50 Tissue Plasminogen Activator Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 795)
id Name Status NCT ID Phase
1 Comparison of Thrombgolytic and Anticoagulation Therapy in Submassive Pulmonary Embolism Unknown status NCT02132689 Phase 4
2 Home Treatment of Pulmonary Embolism Unknown status NCT00214929 Phase 4
3 Low Dose Rt-PA for Acute Normotensive Pulmonary Embolism With RVD Unknown status NCT01531829 Phase 4
4 Low Dose Prolonged Infusion of Tissue Type Plasminogen Activator Therapy in Massive Pulmonary Embolism Unknown status NCT02029456 Phase 4
5 Two Weeks of Low Molecular Weight Heparin for Distal Vein Thrombosis Unknown status NCT01252420 Phase 4
6 Efficacy of Low Molecular Weight Heparin in Superficial Vein Thrombosis Unknown status NCT01245998 Phase 4
7 Comparison of Low-Molecular-Weight Heparin (LMWH) and Unfractionated Heparin (UFH) in Combination With Thrombolytic Treatment of Acute Massive Pulmonary Thromboembolism Unknown status NCT01956955 Phase 4
8 Residual Vein Thrombosis and the Optimal Duration of Low Molecular Weight Heparin in Cancer Patients With Deep Vein Thrombosis Unknown status NCT00450645 Phase 4
9 Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients Unknown status NCT01610141 Phase 4
10 The Study of Warfarin Maintenance Dose in Chinese Patients Unknown status NCT01855737 Phase 4
11 Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Unknown status NCT02453802 Phase 4
12 Normoglycemia and Neurological Outcome Unknown status NCT01137773 Phase 4
13 Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit Unknown status NCT00862160 Phase 4
14 Tinzaparin in the Treatment of the Acute Pulmonary Embolism Completed NCT00711308 Phase 4
15 Post-marketing Study of Monteplase ("Cleactor") in Patients With Acute Pulmonary Embolism Completed NCT00442234 Phase 4
16 Age-adjusted D-dimer Cut-off Levels to Rule Out Pulmonary Embolism Completed NCT01134068 Phase 4
17 A Study of Rivaroxaban for Early Discharge of Low Risk Pulmonary Embolism From the Emergency Department Completed NCT02584660 Phase 4
18 Deferment of Imaging for Pulmonary Embolism Completed NCT00381511 Phase 4
19 Recombinant Streptokinase Versus Urokinase in Pulmonary Embolism in China (RESUPEC) Completed NCT00968929 Phase 4
20 PREPIC 2 : Prevention of Recurrent Pulmonary Embolism by Vena Cava Interruption Completed NCT00457158 Phase 4
21 Protection From Pulmonary Embolism With the Permanent OptEase™ Filter (PROOF) Completed NCT00233740 Phase 4
22 Detection of Pulmonary Embolism With CECT Completed NCT00351754 Phase 4
23 Epoprostenol in Pulmonary Embolism Completed NCT01014156 Phase 4
24 NAC, NaHCO3 and NS Prophylaxis for CTPA in the ED on Suspicion of PE: A Randomized Controlled Trial Completed NCT02483143 Phase 4
25 3 Months' Versus 6 Months' Anticoagulation in Patients With DVT and/or PE Completed NCT00365950 Phase 4
26 STA®-Liatest®D-Di-Exclusion of Venous Thromboembolism Completed NCT01221805 Phase 4
27 Venous Thromboembolic Prophylaxis After Trauma: Three Times a Day Unfractionated Heparin Versus Twice a Day Enoxaparin Completed NCT01729559 Phase 4
28 D-dimer Levels During and After Anticoagulation in Patients With a Previous Venous Thromboembolism: Effects on the Risk of Recurrence Completed NCT00266045 Phase 4
29 D-dimer to Establish Duration of Anticoagulation After Venous Thromboembolism Completed NCT00264277 Phase 4
30 The D-KAF (Dalteparin in Knee-to-Ankle Fracture) Trial Completed NCT00187408 Phase 4
31 Study of IVC Filter Retrieval With the Günther Tulip Vena Cava Filter Completed NCT00196118 Phase 4
32 Rivaroxaban for the Prevention of Venous Thromboembolism in Asian Patients With Cancer Completed NCT01989845 Phase 4
33 12-h and 2-h Urokinase Regimes of Pulmonary Thromboembolism in China Completed NCT00799968 Phase 4
34 Low Dosage of rt-PA in the Treatment of Pulmonary Thromboembolism in China Completed NCT00781378 Phase 4
35 DULCIS (D-dimer and ULtrasonography in Combination Italian Study) Completed NCT00954395 Phase 4
36 The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial Completed NCT00430989 Phase 4
37 Comparison of Warfarin Dosing Using Decision Model Versus Pharmacogenetic Algorithm Completed NCT00511173 Phase 4
38 PREVAIL: PREvention of VTE After Acute Ischemic Stroke With LMWH Enoxaparin ( - VTE: Venous Thromboembolism - LMWH: Low Molecular Weight Heparin) Completed NCT00077805 Phase 4
39 Study to Find Out the Appropriate Initial Dose of the Anticoagulant Drug Phenprocoumon Completed NCT00586287 Phase 4
40 European Active Surveillance Study of Women Taking Hormone Replacement Therapy (HRT) Completed NCT00214903 Phase 4
41 Nadroparin for the Initial Treatment of Pulmonary Thromboembolism Completed NCT00796692 Phase 4
42 Pharmacodynamic Drug Interaction Between Warfarin and Amoxicillin-clavulanic Acid Completed NCT00603317 Phase 4
43 The Blood Saving Effect of Tranexamic Acid in Total Knee Arthroplasty With Rivaroxaban as Thromboprophylaxis Completed NCT02458729 Phase 4
44 Tranexamic Acid in Urologic Surgery Completed NCT00670345 Phase 4
45 Investigation of Coagulation Parameters in Hereditary Haemorrhagic Telangiectasia Completed NCT00230659 Phase 4
46 Cystic Fibrosis and Totally Implantable Vascular Access Devices Completed NCT00244270 Phase 4
47 Efficacy on Pain Following a Procedure for Injecting Sclerotherapeutic Foam Into the Great Saphenous Vein Completed NCT01368159 Phase 4
48 Drug Interaction Between Paracetamol and Warfarin Completed NCT01104337 Phase 4
49 Does Anticoagulant Control Change Following Referral Back to the Primary Care Physician? Completed NCT00735189 Phase 4
50 The Effect and Safety of Different Intensity Anticoagulation Therapy in Elderly Patients With Non-valvular Atrial Fibrillation Completed NCT01438580 Phase 4

Search NIH Clinical Center for Pulmonary Embolism

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: pulmonary embolism

Genetic Tests for Pulmonary Embolism

Genetic tests related to Pulmonary Embolism:

id Genetic test Affiliating Genes
1 Pulmonary Embolism 29

Anatomical Context for Pulmonary Embolism

MalaCards organs/tissues related to Pulmonary Embolism:

39
Lung, Heart, Brain, Testes, Liver, Bone, Kidney

Publications for Pulmonary Embolism

Articles related to Pulmonary Embolism:

(show top 50) (show all 1208)
id Title Authors Year
1
Extracorporeal Membrane Oxygenation in Massive Pulmonary Embolism. ( 28063605 )
2017
2
Axillary artery transection and bilateral pulmonary embolism after anterior shoulder dislocation: case report. ( 28074775 )
2017
3
Acute pulmonary embolism leading to cavitation and large pulmonary abscess: A rare complication of pulmonary infarction. ( 28066704 )
2017
4
Death from pulmonary embolism of cyanoacrylate glue following gastric varix endoscopic injection. ( 28091982 )
2017
5
Pulmonary embolism in non-brain tumor patients after surgery-a retrospective study in China. ( 28088209 )
2017
6
Massive Pulmonary Embolism in Recovery Period of General Anesthesia: Rapid Diagnosis and Successful Rescue by the Guidance of Transthoracic Echocardiography. ( 28091421 )
2017
7
Acute pulmonary embolism: mortality prediction by the 2014 European Society of Cardiology risk stratification model. ( 28077476 )
2017
8
Age-adjusted plasma D-Dimer levels in suspected acute pulmonary embolism - a retrospective, single center study. ( 28075426 )
2017
9
D-Dimer Use and Pulmonary Embolism Diagnosis in Emergency Units: Why Is There Such a Difference in Pulmonary Embolism Prevalence between the United States of America and Countries Outside USA? ( 28085911 )
2017
10
Acute kidney injury and risk of deep vein thrombosis and pulmonary embolism in Taiwan: A nationwide retrospective cohort study. ( 28092798 )
2017
11
Noise-optimized monoenergetic post-processing improves visualization of incidental pulmonary embolism in cancer patients undergoing single-pass dual-energy computed tomography. ( 28070843 )
2017
12
To screen or not to screen for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism. ( 28073030 )
2017
13
Acute pulmonary embolism: mortality prediction by the 2014 European Society of Cardiology risk stratification model. ( 28077478 )
2017
14
Efficacy and Safety of Thrombolytic Therapy in Acute Submassive Pulmonary Embolism: Follow-Up Study. ( 28090232 )
2017
15
Resuscitation of prolonged cardiac arrest from massive pulmonary embolism by extracorporeal membrane oxygenation. ( 28073853 )
2017
16
Whole Exome Sequencing Reveals Severe Thrombophilia in Acute Unprovoked Idiopathic Fatal Pulmonary Embolism. ( 28174134 )
2017
17
Pulmonary embolism in a patient with mild factor VII deficiency after administration of recombinant activated factor VII during a urological procedure. ( 28452972 )
2017
18
Aplastic anemia and risk of deep vein thrombosis and pulmonary embolism: A nationwide cohort study. ( 27923178 )
2017
19
Prognostic value of computed tomography pulmonary angiography indices in patients with cancer-related pulmonary embolism: Data from a multicenter cohort study. ( 28065377 )
2017
20
Assessment of heat shock proteins and endothelial dysfunction in acute pulmonary embolism. ( 26761580 )
2016
21
Gamma-glutamyl transferase and pulmonary embolism. ( 27657510 )
2016
22
Avoiding alert fatigue in pulmonary embolism decision support: a new method to examine 'trigger rates'. ( 27664174 )
2016
23
Ex Vivo Resection and Renal Autotransplantation for the Treatment of a Large Renal Vein Aneurysm Causing Recurrent Pulmonary Embolism and a Coexisting Vascular Malformation: A Case Report. ( 27334478 )
2016
24
The role of NT-proBNP and Apelin in the assessment of right ventricular dysfunction in acute pulmonary embolism. ( 26968282 )
2016
25
Assessment of Right Ventricular Strain by Computed Tomography versus Echocardiography in Acute Pulmonary Embolism. ( 27664798 )
2016
26
Bilateral Pulmonary Embolism Following a Viper Envenomation in France: A Case Report and Review. ( 27175626 )
2016
27
The Diagnostic Role of Adiponectin in Pulmonary Embolism. ( 27042667 )
2016
28
Prospective Randomized Comparison of High-pitch CT at 80a88kVp Under Free Breathing with Standard-pitch CT at 100a88kVp Under Breath-Hold for Detection of Pulmonary Embolism. ( 27639625 )
2016
29
Pulmonary embolism induced by methotrexate in a dermatomyositis patient. ( 27659404 )
2016
30
Plasma copeptin for short term risk stratification in acute pulmonary embolism. ( 26438275 )
2016
31
SU-F-I-36: In-Utero Dose Measurements Within Postmortem Subjects for Estimating Fetal Doses in Pregnant Patients Examined with Pulmonary Embolism, Trauma, and Appendicitis CT. ( 28048838 )
2016
32
Massive Pulmonary Embolism in a Patient with Heparin Induced Thrombocytopenia: Successful Treatment with Dabigatran. ( 27026768 )
2016
33
A Rare Cause of Pulmonary Embolism and Seizure in a Young Man: Antiphospholipid Syndrome. ( 27122957 )
2016
34
PO-07 - Excluding pulmonary embolism in cancer patients using the Wells rule and age-adjusted D-dimer testing: an individual patient data meta-analysis. ( 27161697 )
2016
35
Syncope and collapse in acute pulmonary embolism. ( 27107684 )
2016
36
Right atrial free-floating thrombus in a patient with acute pulmonary embolism. ( 27166001 )
2016
37
Outcome during and after anticoagulant therapy in cancer patients with incidentally found pulmonary embolism. ( 27660517 )
2016
38
Comparison of the wells score with the revised Geneva score for assessing pretest probability of pulmonary embolism in hospitalized elderly patients. ( 27650507 )
2016
39
Pulmonary Hypertension and Pulmonary Aspergilloma-Coexistence of Two Rare Sequelae of Pulmonary Embolism. ( 27408402 )
2016
40
Thrombolytic Therapy by Tissue Plasminogen Activator for Pulmonary Embolism. ( 27628004 )
2016
41
May-Thurner Syndrome With Pulmonary Embolism as the First Presentation Rather Than Deep Vein Thrombosis. ( 27026834 )
2016
42
Serum Apelin 13 Levels in Patients With Pulmonary Embolism. ( 25693918 )
2016
43
Reducing computed tomography radiation dose in diagnosing pulmonary embolism. ( 28083042 )
2016
44
Cardiac thrombus with risk of fulminant pulmonary embolism in paediatric antiphospholipid syndrome. ( 27138626 )
2016
45
Heparin induced thrombocytopenia presenting with deep venous thrombosis and pulmonary embolism successfully treated with rivaroxaban: clinical case report and review of current experiences. ( 27464495 )
2016
46
Homozygous Carrier of Prothrombin G20210A Mutation with Massive Pulmonary Embolism and His Family: Gender Differences of Susceptibility to Mutation. ( 27383881 )
2016
47
Comparison of Cardiac and Non-Cardiac Biomarkers for Risk Stratification in Elderly Patients with Non-Massive Pulmonary Embolism. ( 27219621 )
2016
48
Pulmonary Embolism Masquerading as High Altitude Pulmonary Edema at High Altitude. ( 27768392 )
2016
49
MiR-28-3p as a potential plasma marker in diagnosis of pulmonary embolism. ( 26702486 )
2016
50
Low dose oestrogen combined oral contraception and risk of pulmonary embolism, stroke, and myocardial infarction in five million French women: cohort study. ( 27164970 )
2016

Variations for Pulmonary Embolism

Expression for Pulmonary Embolism

Search GEO for disease gene expression data for Pulmonary Embolism.

Pathways for Pulmonary Embolism

Pathways related to Pulmonary Embolism according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.97 ALB APOH F10 F2 F3 F5
2
Show member pathways
12.6 F10 F2 F3 F5 F9 SERPINC1
3
Show member pathways
12.07 ALB CRP F2 MTHFR PLAT SERPINE1
4
Show member pathways
11.82 F10 F2 F3 F5 F9 PLAT
5
Show member pathways
11.67 F10 F2 F9
6 11.59 FABP3 TNNI3 TNNT2
7 11.42 F10 F2 F3 F5 F9 PLAT
8 10.72 F10 F2 F9
9 10.61 PLAT SERPINE1 SERPINF2

GO Terms for Pulmonary Embolism

Cellular components related to Pulmonary Embolism according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 9.81 APOH F3 PLAT SERPINE1
2 extracellular region GO:0005576 9.77 ALB APOH CRP F10 F2 F3
3 blood microparticle GO:0072562 9.73 ALB F2 SERPINC1 SERPINF2
4 Golgi lumen GO:0005796 9.67 F10 F2 F9
5 endoplasmic reticulum lumen GO:0005788 9.63 ALB F10 F2 F5 F9 SERPINC1
6 platelet alpha granule lumen GO:0031093 9.56 ALB F5 SERPINE1 SERPINF2
7 troponin complex GO:0005861 9.48 TNNI3 TNNT2
8 cardiac myofibril GO:0097512 9.46 TNNI3 TNNT2
9 extracellular space GO:0005615 9.44 ALB APOH CRP F2 F3 F5
10 intrinsic component of external side of plasma membrane GO:0031233 9.4 F10 F3
11 cardiac Troponin complex GO:1990584 9.37 TNNI3 TNNT2
12 extracellular exosome GO:0070062 10.06 ALB APOH CRP F2 F3 F9

Biological processes related to Pulmonary Embolism according to GeneCards Suite gene sharing:

(show all 19)
id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.85 ALB F2 F5 SERPINC1
2 ER to Golgi vesicle-mediated transport GO:0006888 9.83 F10 F2 F5 F9
3 platelet degranulation GO:0002576 9.8 ALB APOH F5 SERPINE1 SERPINF2
4 acute-phase response GO:0006953 9.69 CRP F2 SERPINF2
5 regulation of blood coagulation GO:0030193 9.67 APOH F2 SERPINC1
6 signal peptide processing GO:0006465 9.65 F10 F2 F9
7 positive regulation of blood coagulation GO:0030194 9.63 APOH F2 SERPINE1
8 fibrinolysis GO:0042730 9.62 F2 PLAT SERPINE1 SERPINF2
9 peptidyl-glutamic acid carboxylation GO:0017187 9.61 F10 F2 F9
10 regulation of muscle contraction GO:0006937 9.58 TNNI3 TNNT2
11 negative regulation of blood coagulation GO:0030195 9.58 APOH SERPINE1
12 plasminogen activation GO:0031639 9.57 APOH PLAT
13 negative regulation of ATPase activity GO:0032780 9.56 TNNI3 TNNT2
14 blood coagulation, intrinsic pathway GO:0007597 9.56 APOH F10 F2 F9
15 negative regulation of plasminogen activation GO:0010757 9.54 SERPINE1 SERPINF2
16 blood coagulation, extrinsic pathway GO:0007598 9.54 F10 F3 F9
17 blood coagulation GO:0007596 9.5 F10 F2 F3 F5 F9 PLAT
18 negative regulation of fibrinolysis GO:0051918 9.46 APOH F2 SERPINE1 SERPINF2
19 hemostasis GO:0007599 9.1 F10 F2 F3 F5 F9 SERPINC1

Molecular functions related to Pulmonary Embolism according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 peptidase inhibitor activity GO:0030414 9.61 SERPINC1 SERPINE1 SERPINF2
2 serine-type endopeptidase inhibitor activity GO:0004867 9.58 SERPINC1 SERPINE1 SERPINF2
3 serine-type peptidase activity GO:0008236 9.56 F10 F2 F9 PLAT
4 phospholipid binding GO:0005543 9.5 APOH F10 F3
5 protease binding GO:0002020 9.26 F3 SERPINC1 SERPINE1 SERPINF2
6 troponin C binding GO:0030172 9.16 TNNI3 TNNT2
7 serine-type endopeptidase activity GO:0004252 9.1 F10 F2 F3 F5 F9 PLAT
8 protein binding GO:0005515 10.24 ALB APOH CRP F10 F2 F3

Sources for Pulmonary Embolism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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