MCID: PLM033

Pulmonary Embolism malady

Summaries for Pulmonary Embolism

Sources:
23MedlinePlus, 2CDC, 44Wikipedia, 22MalaCards
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MedlinePlus: A pulmonary embolism is a sudden blockage in a lung artery. the cause is usually a blood clot in the leg called a deep vein thrombosis that breaks loose and travels through the bloodstream to the lung. pulmonary embolism is a serious condition that can cause permanent damage to the affected lung low oxygen levels in your blood damage to other organs in your body from not getting enough oxygen if a clot is large, or if there are many clots, pulmonary embolism can cause death. half the people who have pulmonary embolism have no symptoms. if you do have symptoms, they can include shortness of breath, chest pain or coughing up blood. symptoms of a blood clot include warmth, swelling, pain, tenderness and redness of the leg. the goal of treatment is to break up clots and help keep other clots from forming. nih: national heart, lung, and blood institute23

MalaCards: Pulmonary Embolism, also known as pulmonary artery embolism, is related to thrombosis and antithrombin iii deficiency. An important gene associated with Pulmonary Embolism is PLAT (plasminogen activator, tissue), and among its related pathways are Common Pathway and Gamma-carboxylation of protein precursors. The drugs alteplase,recombinant and anistreplase and the compounds cyclophosphamide and danaparoid have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and lung, and related mouse phenotypes are hematopoietic system and reproductive system.

CDC: DVT/PE are often underdiagnosed and serious, but preventable medical conditions. It is important to know about DVT because it can happen to anybody at any age and can cause serious illness, disability, and in some cases, death. The good news is that DVT is preventable and treatable if discovered early.2

Wikipedia: Pulmonary embolism (PE) is a blockage of the main artery of the lung or one of its branches by a...44 more...

Aliases & Descriptions for Pulmonary Embolism

Sources:
2CDC, 6Disease Ontology, 17Genetics Home Reference, 8DISEASES, 32Novoseek , 23MedlinePlus, 43UMLS, 27NCIt, 40SNOMED-CT, 24MeSH
See all sources

Aliases & Descriptions:

pulmonary embolism 6 17 8 32 23 43
pulmonary artery embolism 6

External Ids:

SNOMED-CT40 266292008, 59282003, 194882001 155326007, more

Related Diseases for Pulmonary Embolism

Sources:
13GeneCards, 14GeneDecks
See all sources

Diseases related to pulmonary embolism by text searches and GeneDecks gene sharing:

(show top 50)    (show all 619)
idRelated DiseaseScoreTop Affiliating Genes
1thrombosis36.7MTHFR, FGB, F5, F2
2antithrombin iii deficiency31.9SERPINC1, MTHFR, FGA, APOH, F5, F2
3venous thrombosis31.9SERPINC1, SERPINA5, SERPINF2, SERPINE1, MTHFR, FGA
4deep vein thrombosis30.5SERPINC1, SERPINE1, VKORC1, MTHFR, CELSR2, FGA
5antiphospholipid syndrome29.8APOH, F2
6von willebrand's disease29.7GP1BA, F9, F5, F3, F2
7hyperprothrombinemia29.7SERPINC1, F2, TAF1, CPB2
8thrombophilia29.0SERPINC1, SERPINF2, SERPINE1, MTHFR, FGA, FGB
9protein s deficiency28.8PIK3C2A, SERPINC1, SERPINE1, MTHFR, CELSR2, FGA
10pulmonary hypertension28.8FGA, PDE5A, THBD, NPPA, NPPB
11q fever28.6APOH, F2, HLA-B, CRP
12klinefelter's syndrome27.9SERPINE1, MTHFR, INS, F5, CRP
13syncope27.9PIK3C2A, MTHFR, F5, TNNC1, TNNI3, TNNT2
14pleurisy27.8VIM, MPO, CRP, PLA2G7
15thromboembolism27.7SERPINC1, SERPINF2, SERPINE1, MTHFR, FGA, APOH
16heparin-induced thrombocytopenia27.6SERPINC1, SERPINE1, MTHFR, APOH, GP1BA, F5
17polycythemia vera27.3SERPINC1, SERPINE1, MPO, GP1BA, IFNA2, F5
18endocarditis26.9PIK3C2A, SERPINC1, APOH, IFNA2, F5, F2
19morbid obesity26.1PIK3C2A, SERPINE1, INS, F5, F2, ALB
20sepsis24.9SERPINC1, SERPINF2, SERPINE1, MPO, FGA, GP1BA
21respiratory failure24.5PIK3C2A, SERPINC1, PAOX, CGB5, INS, F5
22thrombocytopenia24.3PIK3C2A, SERPINC1, SERPINE1, MTHFR, INS, FGA
23sarcoma23.8PIK3C2A, SERPINC1, SERPINE1, VIM, MTHFR, CGB5
24pulmonary disease23.2SERPINC1, SERPINE1, MTHFR, MPO, APOH, F5
25atrial fibrillation22.5PIK3C2A, SERPINC1, SERPINE1, VKORC1, MTHFR, MPO
26blindness21.3PIK3C2A, SERPINC1, SERPINE1, MTHFR, CGB5, MPO
27obesity20.7PIK3C2A, SERPINC1, SERPINF2, SERPINE1, MTHFR, MPO
28pneumonia20.6PIK3C2A, SERPINC1, SERPINF2, SERPINE1, VIM, PAOX
29nephrotic syndrome19.9PIK3C2A, SERPINC1, SERPINF2, SERPINE1, VIM, MPO
30hypertension19.1PIK3C2A, SERPINC1, SERPINF2, SERPINE1, MTHFR, CGB5
31ischemia17.8PIK3C2A, SERPINC1, SERPINE1, VKORC1, VIM, MTHFR
32placental infarction13.9SERPINC1, APOH, F5
33blood protein disease13.8MTHFR, F5, F2
34prothrombin deficiency13.8F9, F3, F2
35sagittal sinus thrombosis13.8SERPINC1, F5, F3
36placental abruption13.8SERPINC1, MTHFR, F5
37porencephaly13.8MTHFR, F5, F2
38factor xii deficiency13.8F5, F3, F2, F13A1
39transient cerebral ischemia13.8MTHFR, FGA, APOH
40factor v deficiency13.8F9, F5, F3, F2
41acquired hemophilia13.8F9, F5, F3, F10
42retinal vascular occlusion13.8SERPINC1, MTHFR, APOH, F5
43scott syndrome13.8F5, F2, F10, TNXA
44hemarthrosis13.8F9, F3, F2, F10
45homocysteine plasma level13.8SERPINC1, MTHFR, F5
46mondor disease13.8APOH, F5
47blood platelet disease13.8SERPINC1, F3, PF4
48afibrinogenemia13.7FGA, FGB
49stroke, ischemic13.7F5, F2
50spinal cord infarction13.7SERPINC1, MTHFR, APOH, F5, F2

Graphical network of the top 20 diseases related to pulmonary embolism:



Graphical network of diseases related to pulmonary embolism

Clinical Features for Pulmonary Embolism

Drugs & Therapeutics for Pulmonary Embolism

Sources:
4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
See all sources

Approved drugs:

Search CenterWatch for pulmonary embolism

Drug clinical trials:

Search ClinicalTrials for pulmonary embolism

Search NIH Clinical Center for pulmonary embolism

Search CenterWatch for pulmonary embolism

Inferred drug relations via UMLS/NDF-RT:

43 28 alteplase,recombinant, anistreplase, papaverine, papaverine hydrochloride, streptokinase, tinzaparin, tinzaparin na, urokinase

Genetic Tests for Pulmonary Embolism

Anatomical Context for Pulmonary Embolism

Sources:
22MalaCards
See all sources

MalaCards organs/tissues related to pulmonary embolism:

22
Brain, Heart, Lung

Phenotypes for genes affiliated with Pulmonary Embolism

Sources:
25MGI
See all sources

MGI Mouse Phenotypes related to pulmonary embolism:

25 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1hematopoietic system phenotypeMP:000539710.0TBX1, ERF, F13A1, GP1BA, CD97
2reproductive system phenotypeMP:00053899.7PLG, F10, CBS, FGA, CELSR2, SERPINA5
3respiratory system phenotypeMP:00053889.5CPB2, TBX1, TNNI3, CALCA, F13A1, CBS
4integument phenotypeMP:00107719.4TBX1, CALCA, CBS, F2, F3, F5
5immune system phenotypeMP:00053879.3CPB2, TKTL1, PLG, PLAT, TBX1, CBS
6renal/urinary system phenotypeMP:00053679.2CPB2, NPPA, PLG, CBS, MAS1, INS
7embryogenesis phenotypeMP:00053809.0PES1, TBX1, TNNT2, ERF, CBS, F2
8liver/biliary system phenotypeMP:00053708.5SOD1, PROS1, PLG, CBS, F9, FABP3
9muscle phenotypeMP:00053697.6NPPB, NPPA, SOD1, DES, PLAT, TBX1
10mortality/agingMP:00107687.1ERF, TNNI3, TNNT2, TBX1, PLAT, PLG
11cardiovascular system phenotypeMP:00053854.4NPPB, F2, F3, F5, F9, MAS1
12homeostasis/metabolism phenotypeMP:00053762.9CPB2, NPPA, SOD1, PROS1, PIK3C2A, F9

Publications for genes affiliated with Pulmonary Embolism

Sources:
35PubMed
See all sources

Articles related to pulmonary embolism:

(show top 50)    (show all 188)
idTitleAuthorsYearAffiliating Genes
1C-reactive protein in acute pulmonary embolism. (21218608)Abul Y.... Celikel T.2011CRP
2Recurrent deep vein thrombosis and pulmonary embolism in a young man with Klinefelter's syndrome and heterozygous mutation of MTHFR- 677C>T and 1298A>C. (20449891)Angel J.R.... Atallah E.2010MTHFR
3Pulmonary Embolism Severity Index and troponin testin g for the selection of low-risk patients with acute symptomatic pulmonary embol ism. (20025646)Moores L.... Yusen R.2010TNNI3
4Clinical usefulness of prothrombin fragment 1+2 in pa tients with suspected pulmonary embolism. (19394681)Gibson N.S.... Buller H.R.2010F2
5Cardiac troponin I levels in acute pulmonary embolism . (20222345)Margato R.... Moreira J.I.2009NPPB
6Thrombophilia-related genetic variations in patients with pulmonary embolism in the main teaching hospital in Jordan. (19618008)Obeidat N.M.... Abu-Khader I.B.2009F2, F5, MTHFR
7Massive pulmonary embolism (18775637)Sanchez O.... Meyer G.2008NPPB
8B-type natriuretic peptide as an indicator of right ventricular dysfunction in acute pulmonary embolism. (17537186)Yardan T.... Guven H.2008NPPB
9Pulmonary artery sarcoma mimicking a pulmonary embolism. (18453737)Sandhu A.... Kuriakose P.2008VIM
10Comparison of 8 biomarkers for prediction of right ventricular hypokinesis 6 months after submassive pulmonary embolism. (18657661)Kline J.A.... Rose G.A.2008NPPB
11C-reactive protein in elderly patients with suspected and confirmed pulmonary embolism. (17456635)Masotti L.... Cappelli R.2007CRP
12Massive pulmonary embolism secondary to anticardiolip in antibody syndrome. (17256569)Vasu T.S.... Lenox R.J.2007APOH
13Massive pulmonary embolism in a Lebanese patient doubly heterozygous for MTHFR and Factor V Leiden presenting with syncope and treated with tenecteplase. (16622615)Isma'eel H.... Arnaout M.S.2006F5, MTHFR
14Pseudo-pulmonary embolism as a sign of acute heparin-induced thrombocytopenia in hemodialysis patients: safety of resuming heparin after disappearance of HIT antibodies. (16902310)Hartman V.... ZachAce P.2006PF4
15Brain natriuretic peptide in hemodynamically stable acute pulmonary embolism. (16405522)SAPhne M.... BA1ller H.R.2006NPPB
16Disseminated coronary occlusions and massive pulmonary embolism in a 40-year-old woman (16555173)Kahles H.... Kehren H.2006PLAT, F3
17N-terminal pro-brain natriuretic peptide or troponin testing followed by echocardiography for risk stratification of acute pulmonary embolism. (16144990)Binder L.... Konstantinides S.2005NPPB
18Efficacy of thrombolytic agents in the treatment of pulmonary embolism. (16264048)Capstick T.... Henry M.T.2005PLAT
19No association between pulmonary embolism or deep vein thrombosis and the -455G/A beta-fibrinogen gene polymorphism. (15795538)Camilleri R.S.... Cohen H.2005FGB
20Symptomatic pulmonary embolism and the risk of recurrent venous thromboembolism. (14718328)Eichinger S.... Kyrle P.A.2004F5
21Should thrombolytic therapy be used in patients with pulmonary embolism? (15049719)Konstantinides S.2004PLAT
22A case of pulmonary embolic metastasis of choriocarcinoma presenting with multiple pulmonary infiltrative shadows (15357272)Suzuki M.... Kawakami Y.2004CGB5
23Prognostic role of brain natriuretic peptide in acute pulmonary embolism. (12742987)Kucher N.... Goldhaber S.Z.2003NPPB
24Frequency of the TAFI -438 G/A and factor XIIIA Val34Leu polymorphisms in patients with objectively proven pulmonary embolism. (12958613)Zidane M.... Huisman M.V.2003F13A1, TAF1, CPB2
25Factor V leiden and morbid obesity in fatal postoperative pulmonary embolism. (11115343)Blaszyk H.... Bjornsson J.2000F5
26Comparison of the risk of pulmonary embolism and deep vein thrombosis in the presence of factor V Leiden or prothrombin G20210A. (10739402)OrdA^A+ez A.J.... Coto E.2000F5
27Factor V Leiden paradox: risk of deep-vein thrombosis but not of pulmonary embolism. (10963193)Bounameaux H.2000F5
28Pulmonary embolism following head positioning for ret inal reattachment surgery in a young patient with factor V leiden mutation. (10980782)Au Eong K.G.... Turner G.S.2000F5
29A contemporary approach to thrombolytic therapy for pulmonary embolism. (10943588)Goldhaber S.Z.2000PLAT
30Clinical outcome of catheter fragmentation and aspiration therapy in patients with acute pulmonary embolism (10466088)Hiramatsu S.... Izumi T.1999PLAT
31The contribution of activated factor XIII to fibrinolytic resistance in experimental pulmonary embolism. (9892598)Reed G.L.... Houng A.K.1999F13A1
32Diagnosis and treatment of acute pulmonary embolism (10546464)AjanoviA8 E.1999PIK3C2A
33Activated protein C resistance is uncommon in sudden death due to pulmonary embolism. (10582351)Rulon J.J.... Gulley M.L.1999F5
34Ischemic colitis, pulmonary embolism, and right atria l thrombosis in a patient with inherited resistance to activated protein C. (9635632)Ludwig D.... Stange E.F.1998F5
35Prehospital thrombolytic treatment of massive pulmonary embolism with reteplase during cardiopulmonary resuscitation. (9783510)Kuisma M.... MalmstrAPm R.1998PLAT
36Mobile thrombus in the right atrium and pulmonary embolism: efficacy of thrombolytic treatment with alteplase (9091727)LA^pez-HaldA^n J.E.... GonzA!lez de la Puente M.A.1997PLAT
37Streptokinase vs alteplase in massive pulmonary embolism. A randomized trial assessing right heart haemodynamics and pulmonary vascular obstruction. (9243149)Meneveau N.... Bassand J.P.1997PLAT
38The efficacy of prophylaxis with low-dose warfarin for prevention of pulmonary embolism following total hip arthroplasty. (9070518)Lieberman J.R.... Amstutz H.C.1997F2
39High antibody levels to prothrombin imply a risk of deep venous thrombosis and pulmonary embolism in middle-aged men--a nested case-control study. (9364981)Palosuo T.... Vaarala O.1997F2
40Relative risk of pulmonary embolism and deep vein thrombosis in association with the factor V Leiden mutation in a United Kingdom population. (9241762)Baglin T.P.... Luddington R.1997F5
41Efficacy of an intravenous low-molecular-weight dermatan sulphate (Desmin) in patients with acute proximal deep venous thrombosis and silent pulmonary embolism. A pilot study. (9100165)Venosi S.... Valentini F.B.1997DES, F3
42Resistance to activated protein C in an unselected population of patients with pulmonary embolism. (8637344)Desmarais S.... Bounameaux H.1996F5
43Pulmonary embolism disclosing activated protein C re sistance (8999481)Strecker A.... Jude B.1996F5
44Pulmonary embolism and deep venous thrombosis during pregnancy or oral contraceptive use: prevalence of factor V Leiden. (8644593)Hirsch D.R.... Goldhaber S.Z.1996F5
45Reduced dose bolus alteplase vs conventional alteplase infusion for pulmonary embolism thrombolysis. An international multicenter randomized trial. The Bolus Alteplase Pulmonary Embolism Group. (8082347)Goldhaber S.Z.... Levine M.N.1994PLAT
46Massive acute pulmonary embolism in protein S deficiency--a case report. (7944258)Kam R.M.... Wong J.1994SERPINC1
47Effects of intravenous urokinase versus alteplase on total pulmonary resistance in acute massive pulmonary embolism: a European multicenter double-blind trial. The European Cooperative Study Group for Pulmonary Embolism. (1732347)Meyer G.... Verstraete M.1992PLAT
48Hypofibrinolysis in patients with a history of idiopathic deep vein thrombosis and/or pulmonary embolism. (1631786)Grimaudo V.... Kruithof E.K.1992PLAT, SERPINE1
49Comparative thrombolytic properties of bolus injections and continuous infusions of a chimeric (t-PA/u-PA) plasminogen activator in a hamster pulmonary embolism model. (1906351)Lu H.R.... Collen D.1991PLAT
50Emergency treatment with recombinant tissue plasminogen activator of pulmonary embolism in a pregnant woman with antithrombin III deficiency. (2121034)Baudo F.... deCataldo F.1990SERPINC1

Expression for genes affiliated with Pulmonary Embolism

Sources:
1BioGPS
See all sources
Expression patterns in normal tissues for genes affiliated with Pulmonary Embolism

Pathways for genes affiliated with Pulmonary Embolism

Sources:
38Reactome, 34PharmGKB, 41Thomson Reuters, 10EMD Millipore, 36QIAGEN, 20KEGG, 37R&D Systems
See all sources

Compounds for genes affiliated with Pulmonary Embolism

Sources:
32Novoseek , 34PharmGKB, 9DrugBank, 18HMDB, 42Tocris Bioscience
See all sources

Compounds related to pulmonary embolism according to GeneDecks:

(show top 50)    (show all 301)
idCompoundScoreTop Affiliating Genes
1cyclophosphamide32 34 9 9 13.5NPPB, F9, APOH
2danaparoid32 10.4SERPINC1, F5, F3, F2, F10, TNXA
3fondaparinux32 10.3SERPINC1, F9, F5, F3, F2, TNXA
4citrate32 10.2PF4, F9, FABP3, PIK3C2A, F10
5fibrinopeptide a32 10.2SERPINC1, SERPINF2, FGA, F2, PLAT, PF4
6ristocetin32 10.2SERPINF2, SERPINC1, PLAT, GP1BA, F2, F9
7argatroban32 9 9 12.2FGA, F5, F3, F2, F10, TNXA
8heparinoids32 10.1F5, F3, F2, F10, F13A1, SERPINC1
9ancrod32 10.0F5, F2, F10, PLAT, THBD, FGA
10coumarins32 10.0VKORC1, F10, F2, F3, F5, F9
11protamine sulfate32 10.0F5, PLAT, SERPINC1, F3, F2, F10
12hirudin32 9.9TNXA, PF4, THBD, F10, F5, SERPINC1
13tirofiban32 9 9 11.8SERPINC1, PLAT, CRP, F10, F2, F3
14epsilon aminocaproic acid32 9.8F2, F3, PLG, PLAT, SERPINC1, SERPINF2
15ptca32 9.8PIK3C2A, SERPINF2, FGA, APOH, F3, TNNT2
16glucose32 9.8DES, TKTL1, GP1BA, IFNA2, PLG
17gamma-carboxyglutamic acid32 9.8VKORC1, F9, F5, F3, F2, F10
18spectrozyme32 9.7PLAT, F5, F3, SERPINC1, F2, F10
1911-dehydrothromboxane b232 9.7SERPINE1, THBD, FGA, APOH, F2, CBS
20coumarin32 18 10.7HLA-B, F10, FGA, VKORC1, SERPINC1, F9
21bivalirudin32 9 9 11.7THBD, SERPINC1, MPO, FGA, F5, F3
22tranexamic acid32 9 9 11.7SERPINE1, F9, PLAT, PLG, SERPINC1
23Drotrecogin alfa9 9 10.7PROS1, SERPINA5, SERPINE1, F5, F2, PF4
24dermatan sulfate32 9.7F9, F5, F3, F2, F10, TNXA
25aprotinin32 9 9 11.5SERPINC1, SERPINF2, FGA, GP1BA, F9, F5
26protamine32 9.5F3, F2, F10, TNXA, PLAT, PF4
27desmopressin32 42 9 9 12.5SERPINC1, SERPINF2, SERPINE1, GP1BA, F9, F5
28polyethylene glycol32 9.3F10, IFNA2, SERPINC1, PF4, NPPA, THBD
29pge132 9.1PIK3C2A, SERPINE1, CGB5, FGA, APOH, F5
30p00232 9.1NPPB, F5, MTHFR, APOH, FABP3, CBS
31epinephrine32 9 18 9 12.0FGA, PIK3C2A, SERPINF2, CGB5, GP1BA, INS
32endotoxin32 8.6PLA2G7, SERPINF2, HLA-B, SERPINE1, FGA, APOH
33homocysteine32 18 9.5PLAT, THBD, NPPB, PIK3C2A, SERPINC1, SERPINE1
34perindopril32 34 9 9 11.3SERPINE1, NPPB, NPPA, ACE, THBD, ALB
35testosterone32 9 18 9 11.2PIK3C2A, PDE5A, SERPINC1, SERPINF2, HLA-B, VIM
36warfarin32 34 9 18 9 12.2THBD, ACE, PF4, PIK3C2A, SERPINC1, SERPINA5
37aspirin32 34 18 10.1SERPINC1, SERPINE1, MTHFR, NPPB, THBD, CGB5
38kininogen32 7.4SERPINC1, SERPINF2, SERPINE1, MPO, APOH, GP1BA
39heparin32 9 18 9 10.4ALB, TNXA, PLG, DES, PROS1, TNNT2
40creatinine32 7.1F5, F3, HLA-B, TNNI3, TNNT2, TNXA
41prostacyclin32 6.9THBD, PROS1, SOD1, NPPA, NPPB, ACE
42calcium32 9 18 9 9.8TNNC1, TNNI3, TNNT1, TNNT2, TNXA, PLA2G7
43cholesterol32 9 18 9 9.5CRP, PLA2G7, PLAT, PF4, ACE, THBD
44arginine32 6.3SERPINF2, VIM, CGB5, INS, APOH, F9
45vegf32 6.2PIK3C2A, SERPINC1, SERPINF2, SERPINE1, VIM, F5
46serine32 6.2SERPINC1, SERPINA5, SERPINF2, SERPINE1, VIM, MTHFR
47alanine32 6.1PIK3C2A, TNNT2, TNXA, CRP, PF4, THBD
48fibrinogen32 5.9F9, CPB2, F5, F3, ALB, CBS
49lactate32 5.1CALCA, HLA-B, TNNI3, TNNT2, CRP, PF4
50lipid32 4.8CGB5, CRP, SERPINF2, PLG, TNXA, CBS

GO Terms for genes affiliated with Pulmonary Embolism

Sources:
12Gene Ontology
See all sources

Cellular components related to pulmonary embolism according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granuleGO:03109110.2SERPINA5, FGA, FGB
2fibrinogen complexGO:00557710.2SERPINF2, FGA, FGB
3troponin complexGO:00586110.0TNNT2, TNNT1, TNNI3, TNNC1
4Golgi lumenGO:0057969.2PROS1, F10, F2, F9, INS
5platelet alpha granule lumenGO:0310938.9PROS1, SERPINF2, SERPINE1, FGA, FGB, F5
6extracellular regionGO:0055765.3CALCA, OTOR, CRP, PLA2G7, PLAT, PLG
7extracellular spaceGO:0056154.7PF4, ACE, THBD, SOD1, NPPB, CPB2

Biological processes related to pulmonary embolism according to GeneDecks:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1blood coagulation, extrinsic pathwayGO:00759810.4F10, F3, F9
2blood coagulation, intrinsic pathwayGO:00759710.3F10, F2, F9, GP1BA, APOH
3blood vessel morphogenesisGO:04851410.3PLAT, TBX1, SERPINF2
4positive regulation of blood coagulationGO:03019410.2F2, APOH, SERPINE1
5regulation of blood vessel sizeGO:05088010.2NPPB, NPPA, CBS
6peptidyl-glutamic acid carboxylationGO:01718710.1PROS1, F10, F2, F9, VKORC1
7response to calcium ionGO:05159210.0FGA, FGB, TNNT2, NPPB
8negative regulation of blood coagulationGO:0301959.9THBD, APOH, SERPINE1
9negative regulation of proteolysisGO:0458619.9PLAT, F2, INS, SERPINA5
10spermine catabolic processGO:0462089.9SMOX, PAOX
11negative regulation of fibrinolysisGO:0519189.7CPB2, THBD, PLG, F2, APOH, SERPINE1
12muscle filament slidingGO:0300499.7DES, TNNT2, TNNT1, TNNI3, TNNC1, VIM
13fibrinolysisGO:0427309.7SERPINF2, SERPINE1, GP1BA, F2, PLAT, PLG
14acute-phase responseGO:0069539.5SERPINF2, INS, F2, CRP
15proteolysisGO:0065089.1F9, F2, F10, PLAT, PLG, ACE
16regulation of blood pressureGO:0082178.7CALCA, ACE, SOD1, NPPA, NPPB
17platelet degranulationGO:0025768.2SOD1, PROS1, PF4, SERPINF2, SERPINE1, FGA
18platelet activationGO:0301688.0SOD1, PROS1, PF4, PLG, F13A1, ALB
19blood coagulationGO:0075966.8SERPINC1, F13A1, PLAT, PLG, PF4, PDE5A

Molecular functions related to pulmonary embolism according to GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1troponin T bindingGO:03101410.3TNNC1, TNNI3, TNNT1
2eukaryotic cell surface bindingGO:04349910.2APOH, FGB, FGA, SERPINF2
3spermine:oxygen oxidoreductase (spermidine-forming) activityGO:05290110.1SMOX, PAOX
4polyamine oxidase activityGO:0465929.9SMOX, PAOX
5heparin bindingGO:0082019.7SERPINC1, SERPINA5, MPO, APOH, PF4
6protease bindingGO:0020209.6SERPINC1, F3, INS, SERPINE1, SERPINF2, SERPINA5
7receptor bindingGO:0051029.0NPPB, NPPA, HLA-B, CALCA, F2, FGB
8protein bindingGO:0055154.2F10, CALCA, TNNC1, TNNI3, CRP, PLAT

Sources for Pulmonary Embolism

2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS