MCID: PLM033
MIFTS: 62

Pulmonary Embolism

Categories: Cardiovascular diseases, Respiratory diseases

Aliases & Classifications for Pulmonary Embolism

Summaries for Pulmonary Embolism

MedlinePlus : 40 A pulmonary embolism is a sudden blockage in a lung artery. The cause is usually a blood clot in the leg called a deep vein thrombosis that breaks loose and travels through the bloodstream to the lung. Pulmonary embolism is a serious condition that can cause Permanent damage to the affected lung Low oxygen levels in your blood Damage to other organs in your body from not getting enough oxygen If a clot is large, or if there are many clots, pulmonary embolism can cause death. Half the people who have pulmonary embolism have no symptoms. If you do have symptoms, they can include shortness of breath, chest pain or coughing up blood. Symptoms of a blood clot include warmth, swelling, pain, tenderness and redness of the leg. The goal of treatment is to break up clots and help keep other clots from forming. NIH: National Heart, Lung, and Blood Institute

MalaCards based summary : Pulmonary Embolism, also known as pulmonary artery embolism, is related to chronic thromboembolic pulmonary hypertension and respiratory failure, and has symptoms including snoring, hemoptysis and coughing. An important gene associated with Pulmonary Embolism is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Heparin and Nitric Oxide have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and testes, and related phenotypes are cardiovascular system and homeostasis/metabolism

Disease Ontology : 12 An artery disease characterized by a blockage of the main artery of the lung or one of its branches by a substance that has travelled from elsewhere in the body, e.g. a blood clot.

CDC : 3 The Joint Commission selected CDC’s VTE educational resources for use in their Compendium of Resources, which provides healthcare providers and health educators with reliable, up-to-date patient education on VTE.Learn more about the compendium and access it here.

PubMed Health : 59
About pulmonary embolism: Pulmonary embolism (PULL-mun-ary EM-bo-lizm), or PE, is a sudden blockage in a lung artery. The blockage usually is caused by a blood clot that travels to the lung from a vein in the leg.A clot that forms in one part of the body and travels in the bloodstream to another part of the body is called an embolus (EM-bo-lus).PE is a serious condition that can:

Wikipedia : 72 Pulmonary embolism (PE) is a blockage of an artery in the lungs by a substance that has moved from... more...

Related Diseases for Pulmonary Embolism

Diseases related to Pulmonary Embolism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 452)
# Related Disease Score Top Affiliating Genes
1 chronic thromboembolic pulmonary hypertension 32.8 CRP NPPB
2 respiratory failure 32.0 ALB CRP F3
3 protein c deficiency 31.4 F2 F5 F9 MTHFR SERPINC1
4 inferior myocardial infarction 30.6 NPPB PLAT
5 thrombophilia due to thrombin defect 30.4 APOH F10 F2 F3 F5 MTHFR
6 heparin-induced thrombocytopenia 30.4 F10 F3 SERPINC1
7 inferior vena cava interruption 30.3 F5 MTHFR SERPINE1
8 pulmonary hypertension 30.3 F3 NPPB PLAT SERPINC1 SERPINE1
9 sticky platelet syndrome 30.0 F5 SERPINC1 SERPINE1
10 cardiogenic shock 29.9 CRP NPPB PLAT
11 acute cor pulmonale 29.9 NPPB PLAT SERPINE1 SERPINF2
12 may-thurner syndrome 29.8 APOH F5
13 sagittal sinus thrombosis 29.8 F2 F3 F5 SERPINC1
14 patent foramen ovale 29.8 APOH F2 F5 MTHFR PLAT SERPINC1
15 lemierre's syndrome 29.8 CRP F3 MTHFR SERPINE1
16 thrombocytosis 29.7 CRP F2 F3 SERPINC1
17 atrial fibrillation 29.7 F10 F2 NPPB PLAT
18 coronary thrombosis 29.7 F3 PLAT SERPINC1 SERPINE1
19 splenic infarction 29.7 APOH F2
20 kwashiorkor 29.6 ALB F2
21 cardiac tamponade 29.6 F2 F9 NPPB
22 protein s deficiency 29.5 APOH F2 F3 F5 MTHFR SERPINC1
23 varicose veins 29.5 F2 F5 MTHFR SERPINC1
24 mediastinitis 29.5 CRP F5
25 hemophilia 29.4 F2 F3 F9
26 peritonitis 29.4 ALB CRP F2
27 afibrinogenemia 29.3 F10 F2 F3 F5
28 pulmonary edema 29.3 CRP F2 NPPB SERPINC1
29 buerger disease 29.3 APOH F2 MTHFR SERPINE1
30 von willebrand's disease 29.2 F2 F3 F5 F9
31 factor xi deficiency 29.1 F2 F3 F9 SERPINC1
32 antithrombin iii deficiency 29.0 APOH F10 F2 F5 MTHFR SERPINC1
33 catastrophic antiphospholipid syndrome 29.0 APOH F3 F5 MTHFR SERPINE1
34 ischemic colitis 29.0 APOH F2 F5 SERPINC1 SERPINE1
35 infective endocarditis 28.9 APOH CRP F2 SERPINE1 TNNI3
36 factor vii deficiency 28.9 F10 F2 F3 F9
37 liver cirrhosis 28.9 ALB F2 SERPINC1 SERPINF2
38 endocarditis 28.9 ALB APOH CRP F2 SERPINC1 TNNI3
39 vein disease 28.9 ALB F2 F3 F5 MTHFR PLAT
40 thrombophlebitis 28.7 APOH F2 F5 MTHFR PLAT SERPINC1
41 budd-chiari syndrome 28.7 APOH F2 F3 F5 MTHFR SERPINC1
42 acquired hemophilia 28.7 F10 F3 F5 F9
43 coronary artery anomaly 28.7 CRP MTHFR NPPB PLAT SERPINE1 TNNI3
44 hemophilia a 28.7 F10 F3 F5 F9
45 portal vein thrombosis 28.7 APOH F2 F5 MTHFR SERPINC1 SERPINE1
46 marantic endocarditis 28.6 F2 F3 MTHFR PLAT SERPINC1 SERPINF2
47 afibrinogenemia, congenital 28.6 F2 F3 PLAT SERPINC1 SERPINE1 SERPINF2
48 dilated cardiomyopathy 28.5 ALB CRP FABP3 NPPB TNNI3 TNNT2
49 antiphospholipid syndrome 28.5 APOH F10 F2 F3 F5 MTHFR
50 thrombosis 28.3 APOH F10 F2 F3 F5 F9

Graphical network of the top 20 diseases related to Pulmonary Embolism:



Diseases related to Pulmonary Embolism

Symptoms & Phenotypes for Pulmonary Embolism

UMLS symptoms related to Pulmonary Embolism:


snoring, hemoptysis, coughing

MGI Mouse Phenotypes related to Pulmonary Embolism:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.93 PLAT SERPINC1 SERPINE1 CRP F10 TNNI3
2 homeostasis/metabolism MP:0005376 9.83 PLAT ALB SERPINC1 APOH SERPINE1 CRP
3 mortality/aging MP:0010768 9.47 MTHFR PLAT ALB SERPINC1 APOH SERPINE1

Drugs & Therapeutics for Pulmonary Embolism

PubMedHealth treatment related to Pulmonary Embolism: 59

Pulmonary embolism (PE) is treated with medicines, procedures, and other therapies. The main goals of treating PE are to stop the blood clot from getting bigger and keep new clots from forming.Treatment may include medicines to thin the blood and slow its ability to clot. If your symptoms are life threatening, your doctor may give you medicine to quickly dissolve the clot. Rarely, your doctor may use surgery or another procedure to remove the clot.

Drugs for Pulmonary Embolism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 359)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9005-49-6 46507594 772
2
Nitric Oxide Approved Phase 4,Phase 2,Phase 1 10102-43-9 145068
3
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-78-2 2244
4
Furosemide Approved, Vet_approved Phase 4,Phase 3 54-31-9 3440
5
Warfarin Approved Phase 4,Phase 3,Phase 2,Phase 1 81-81-2 54678486 6691
6
Tinzaparin Approved Phase 4,Phase 2,Phase 3 9041-08-1, 9005-49-6 25244225
7
Tranylcypromine Approved, Investigational Phase 4 155-09-9 441233
8
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2 1197-18-8 5526
9
Phenprocoumon Approved, Investigational Phase 4,Phase 3 435-97-2 54680692 9908
10
Rivaroxaban Approved Phase 4,Phase 3,Phase 2,Phase 1 366789-02-8
11 Fondaparinux Approved, Investigational Phase 4,Phase 2,Phase 3,Early Phase 1 104993-28-4
12 Nadroparin Approved, Investigational Phase 4,Phase 2,Phase 3 9041-08-1
13
Benzocaine Approved, Investigational Phase 4,Phase 3 1994-09-7, 94-09-7 2337
14
Dalteparin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9005-49-6
15
Thrombin Approved, Investigational Phase 4,Phase 3,Phase 2
16
Acetaminophen Approved Phase 4,Phase 2,Phase 1 103-90-2 1983
17
Drospirenone Approved Phase 4 67392-87-4 68873
18
Iodine Approved, Investigational Phase 4 7553-56-2 807
19
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613 2171
20
Acenocoumarol Approved, Investigational Phase 4,Phase 3 152-72-7 54676537 9052
21
Apixaban Approved Phase 4,Phase 3,Phase 2,Phase 1 503612-47-3 10182969
22 Edoxaban Approved Phase 4,Phase 3,Phase 2 480449-70-5
23
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
24
Epoprostenol Approved Phase 4 61849-14-7, 35121-78-9 5282411 5280427
25
Pancrelipase Approved, Investigational Phase 4 53608-75-6
26
Streptokinase Approved, Investigational Phase 4 9002-01-1
27
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
28
Xylometazoline Approved, Investigational Phase 4 526-36-3 5709
29
Verapamil Approved Phase 4 52-53-9 2520
30 fluindione Approved, Investigational Phase 4 957-56-2
31
Polidocanol Approved Phase 4 9002-92-0
32
Zinc Approved, Investigational Phase 4 7440-66-6 32051 23994
33 tannic acid Approved, Nutraceutical Phase 4,Phase 3
34 Kava Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 9000-38-8
35
Menadione Approved, Nutraceutical Phase 4,Phase 3,Phase 2 58-27-5 4055
36
Phytonadione Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2 84-80-0 5284607 4812
37
Fibrinolysin Investigational Phase 4,Phase 3,Phase 2 9004-09-5
38 Dabigatran Phase 4,Phase 3,Phase 2
39 calcium heparin Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
40
Salmeterol xinafoate Phase 4 94749-08-3 56801
41 Tiotropium Bromide Phase 4 136310-93-5
42
Fluticasone Phase 4 80474-14-2, 90566-53-3 22833648 62924
43 Analgesics Phase 4,Phase 2,Phase 3
44 diuretics Phase 4,Phase 3
45 glucocorticoids Phase 4,Phase 2
46
protease inhibitors Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
47 Respiratory System Agents Phase 4,Phase 2,Phase 1
48 Fibrin fragment D Phase 4,Phase 3,Phase 2
49 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
50 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 725)

# Name Status NCT ID Phase Drugs
1 Comparison of Thrombgolytic and Anticoagulation Therapy in Submassive Pulmonary Embolism Unknown status NCT02132689 Phase 4 Actilyse (Thrombolytic therapy);Heparine (Standard anticoagulation therapy)
2 Home Treatment of Pulmonary Embolism Unknown status NCT00214929 Phase 4
3 Low Dose Rt-PA for Acute Normotensive Pulmonary Embolism With RVD Unknown status NCT01531829 Phase 4 Recombinant tissue plasminogen activator (rt-PA);Low Molecular Weight Heparin
4 Low Dose Prolonged Infusion of Tissue Type Plasminogen Activator Therapy in Massive Pulmonary Embolism Unknown status NCT02029456 Phase 4 25 mg Actilyse ( Boehringer Ingelheim, Germany) infusion in 6 hours
5 Two Weeks of Low Molecular Weight Heparin for Distal Vein Thrombosis Unknown status NCT01252420 Phase 4 Enoxaparin
6 Comparison of Low-Molecular-Weight Heparin (LMWH) and Unfractionated Heparin (UFH) in Combination With Thrombolytic Treatment of Acute Massive Pulmonary Thromboembolism Unknown status NCT01956955 Phase 4 enoxaparin ,alteplase, unfractionated heparin
7 Efficacy of Low Molecular Weight Heparin in Superficial Vein Thrombosis Unknown status NCT01245998 Phase 4 Dalteparin;Dalteparin
8 Residual Vein Thrombosis and the Optimal Duration of Low Molecular Weight Heparin in Cancer Patients With Deep Vein Thrombosis Unknown status NCT00450645 Phase 4 low molecular weight heparin
9 Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients Unknown status NCT01610141 Phase 4
10 The Study of Warfarin Maintenance Dose in Chinese Patients Unknown status NCT01855737 Phase 4 Warfarin
11 Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Unknown status NCT02453802 Phase 4 Tranexamic Acid 5%,5ml/amp;Tranexamic Acid 5%,5ml/amp;rivaroxaban (10mg);0.9% Normal Saline;0.9% Normal Saline
12 Exhaled NO Based Treatment of Chronic Obstructive Pulmonary Disease (COPD), ICS/LABA Versus LAMA Unknown status NCT02546349 Phase 4 fluticasone/salmeterol, tiotropium
13 A Safety and Efficacy Study for Implantation and Retrieval Procedures Using the VENATECH® Retrieval Filter System Unknown status NCT02674672 Phase 4
14 Tinzaparin in the Treatment of the Acute Pulmonary Embolism Completed NCT00711308 Phase 4 tinzaparin;acenocoumarol
15 A Study of Rivaroxaban for Early Discharge of Low Risk Pulmonary Embolism From the Emergency Department Completed NCT02584660 Phase 4 Rivaroxaban;Standard-of-care
16 Age-adjusted D-dimer Cut-off Levels to Rule Out Pulmonary Embolism Completed NCT01134068 Phase 4
17 Post-marketing Study of Monteplase ("Cleactor") in Patients With Acute Pulmonary Embolism Completed NCT00442234 Phase 4 Monteplase
18 Deferment of Imaging for Pulmonary Embolism Completed NCT00381511 Phase 4 low molecular weight heparin
19 Recombinant Streptokinase Versus Urokinase in Pulmonary Embolism in China (RESUPEC) Completed NCT00968929 Phase 4 Recombinant Streptokinase;Urokinase
20 PREPIC 2 : Prevention of Recurrent Pulmonary Embolism by Vena Cava Interruption Completed NCT00457158 Phase 4
21 Epoprostenol in Pulmonary Embolism Completed NCT01014156 Phase 4 epoprostenol
22 Protection From Pulmonary Embolism With the Permanent OptEase™ Filter (PROOF) Completed NCT00233740 Phase 4
23 Detection of Pulmonary Embolism With CECT Completed NCT00351754 Phase 4 Isovue
24 NAC, NaHCO3 and NS Prophylaxis for CTPA in the ED on Suspicion of PE: A Randomized Controlled Trial Completed NCT02483143 Phase 4 NAC;NaHCO3;Normal Saline
25 3 Months' Versus 6 Months' Anticoagulation in Patients With DVT and/or PE Completed NCT00365950 Phase 4 Duration of anticoagulation;Warfarin duration
26 STA®-Liatest®D-Di-Exclusion of Venous Thromboembolism Completed NCT01221805 Phase 4
27 Venous Thromboembolic Prophylaxis After Trauma: Three Times a Day Unfractionated Heparin Versus Twice a Day Enoxaparin Completed NCT01729559 Phase 4 5000 Units unfractionated Heparin Q 8 hr;30mg enoxaparin Q12 hr
28 D-dimer Levels During and After Anticoagulation in Patients With a Previous Venous Thromboembolism: Effects on the Risk of Recurrence Completed NCT00266045 Phase 4
29 Comprehensive Cardiothoracic Dual Source CT for the Early Triage of Patients With Acute Chest Pain Completed NCT01067456 Phase 4
30 D-dimer to Establish Duration of Anticoagulation After Venous Thromboembolism Completed NCT00264277 Phase 4 Vitamin K antagonist (Coumarin anticoagulants)
31 The D-KAF (Dalteparin in Knee-to-Ankle Fracture) Trial Completed NCT00187408 Phase 4 Low Molecular Weight Heparin (dalteparin)
32 Study of IVC Filter Retrieval With the Günther Tulip Vena Cava Filter Completed NCT00196118 Phase 4
33 Rivaroxaban for the Prevention of Venous Thromboembolism in Asian Patients With Cancer Completed NCT01989845 Phase 4 Rivaroxaban
34 12-h and 2-h Urokinase Regimes of Pulmonary Thromboembolism in China Completed NCT00799968 Phase 4 Urokinase;Urokinase
35 Low Dosage of rt-PA in the Treatment of Pulmonary Thromboembolism in China Completed NCT00781378 Phase 4 rt-PA;rt-PA
36 DULCIS (D-dimer and ULtrasonography in Combination Italian Study) Completed NCT00954395 Phase 4
37 The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial Completed NCT00430989 Phase 4 Nitrous Oxide;Nitrous Oxide
38 Comparison of Warfarin Dosing Using Decision Model Versus Pharmacogenetic Algorithm Completed NCT00511173 Phase 4
39 PREVAIL: PREvention of VTE After Acute Ischemic Stroke With LMWH Enoxaparin ( - VTE: Venous Thromboembolism - LMWH: Low Molecular Weight Heparin) Completed NCT00077805 Phase 4 Enoxaparin sodium
40 Study to Find Out the Appropriate Initial Dose of the Anticoagulant Drug Phenprocoumon Completed NCT00586287 Phase 4 Phenprocoumon
41 European Active Surveillance Study of Women Taking Hormone Replacement Therapy (HRT) Completed NCT00214903 Phase 4
42 Nadroparin for the Initial Treatment of Pulmonary Thromboembolism Completed NCT00796692 Phase 4 Nadroparin;Unfractionated heparin(UFH)
43 The Blood Saving Effect of Tranexamic Acid in Total Knee Arthroplasty With Rivaroxaban as Thromboprophylaxis Completed NCT02458729 Phase 4 Tranexamic Acid 5%,5ml/amp (intraoperative);Tranexamic Acid 5%,5ml/amp (3 hours after operation);0.9% Normal Saline (intraoperative);0.9% Normal Saline (3 hours after operation);rivaroxaban (10mg)
44 Pharmacodynamic Drug Interaction Between Warfarin and Amoxicillin-clavulanic Acid Completed NCT00603317 Phase 4 Firstly : Amoxicillin-Clavulanic acid and secondly : Placebo;Firstly : Placebo and secondly : Amoxicillin-Clavulanic acid
45 Safety of Low Dose IV Contrast CT Scanning in Chronic Kidney Disease Completed NCT02476526 Phase 4 Low Volume iso-osmolar non-ionic radio contrast medium;Acetylcysteine Inhalation;Sodium Bicarbonate Solution
46 Tranexamic Acid in Urologic Surgery Completed NCT00670345 Phase 4 Tranexamic Acid;Placebo
47 Investigation of Coagulation Parameters in Hereditary Haemorrhagic Telangiectasia Completed NCT00230659 Phase 4
48 Cancer Venous Thromboembolism (VTE) Completed NCT02073682 Phase 4 Edoxaban;Dalteparin
49 Efficacy on Pain Following a Procedure for Injecting Sclerotherapeutic Foam Into the Great Saphenous Vein Completed NCT01368159 Phase 4
50 Cystic Fibrosis and Totally Implantable Vascular Access Devices Completed NCT00244270 Phase 4

Search NIH Clinical Center for Pulmonary Embolism

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: pulmonary embolism

Genetic Tests for Pulmonary Embolism

Genetic tests related to Pulmonary Embolism:

# Genetic test Affiliating Genes
1 Pulmonary Embolism 28

Anatomical Context for Pulmonary Embolism

MalaCards organs/tissues related to Pulmonary Embolism:

38
Lung, Heart, Testes, Brain, Kidney, Breast, Liver

Publications for Pulmonary Embolism

Articles related to Pulmonary Embolism:

(show top 50) (show all 1271)
# Title Authors Year
1
Cement pulmonary embolism as a complication of percutaneous vertebroplasty in cancer patients. ( 29422089 )
2018
2
Optimizing Pulmonary Embolism Computed Tomography in the Age of Individualized Medicine: A Prospective Clinical Study. ( 29438139 )
2018
3
Computed tomography pulmonary angiography is overused to diagnose pulmonary embolism in the emergency department of academic community hospital. ( 29441158 )
2018
4
Utility of a Clinical Prediction Rule to Exclude Pulmonary Embolism Among Low-Risk Emergency Department Patients: Reason to PERC Up. ( 29450510 )
2018
5
Mesoaortic compression of a left-sided inferior vena-cava presenting as recurrent pulmonary embolism in a child-a novel anatomic thrombophilia? ( 29350462 )
2018
6
Society of Interventional Radiology Position Statement on Catheter-Directed Therapy for Acute Pulmonary Embolism. ( 29422427 )
2018
7
Therapeutic Anticoagulation for Pulmonary Embolism during First Trimester Surgical Abortion: Two Case Reports. ( 29428851 )
2018
8
Ultrasound-Assisted Catheter-Directed Thrombolysis for Submassive Pulmonary Embolism. ( 29436310 )
2018
9
Prevalence of Pulmonary Embolism in Patients With Syncope. ( 29379959 )
2018
10
The YEARS algorithm for suspected pulmonary embolism:shorter visit time and reduced costs at the Emergency department. ( 29431911 )
2018
11
Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients: The PROPER Randomized Clinical Trial. ( 29450523 )
2018
12
Incidental pulmonary embolism in suspected stroke patients undergoing carotid CT angiography. ( 29426964 )
2018
13
Lesson of the month 2: Pulmonary embolism in a patient on rivaroxaban and concurrent carbamazepine. ( 29436450 )
2018
14
Prognostic assessment for patients with cancer and incidental pulmonary embolism. ( 29445314 )
2018
15
Clinical value of cardiac color ultrasound and cardiac troponin T combined with dynamic electrocardiogram in treatment of acute pulmonary embolism. ( 29434803 )
2018
16
Severe pulmonary embolism was secondary to cement inferior vena cava embolism after percutaneous vertebroplasty. ( 29428532 )
2018
17
Recognition of unprovoked (idiopathic) pulmonary embolism-Prospective observational study. ( 29414454 )
2018
18
An unusual presentation of pulmonary embolism leading to infarction, cavitation, abscess formation and bronchopleural fistulation. ( 29437738 )
2018
19
Imaging for Pulmonary Embolism in Sickle Cell Disease: a 17-Year Experience. ( 29419477 )
2018
20
Missed Massive Pulmonary Embolism and the Hidden Threat of a Distal Deep Vein Thrombosis. ( 29435465 )
2018
21
A new method of CT for the cardiac measurement: correlation of computed tomography measured cardiac parameters and pulmonary obstruction index to assess cardiac morphological changes in acute pulmonary embolism patients. ( 29417409 )
2018
22
Impact of ethnicity on outcomes after pulmonary embolism: an observational study in South Auckland. ( 28934774 )
2017
23
Cutaneous lupus erythematosus and the risk of deep venous thrombosis and pulmonary embolism: A Danish nationwide cohort study. ( 28618892 )
2017
24
Pulmonary embolism and internal jugular vein thrombosis as evocative clues of Lemierre's syndrome: A case report and review of the literature. ( 28352635 )
2017
25
D-Dimer Use and Pulmonary Embolism Diagnosis in Emergency Units: Why Is There Such a Difference in Pulmonary Embolism Prevalence between the United States of America and Countries Outside USA? ( 28085911 )
2017
26
Marantic endocarditis and paraneoplastic pulmonary embolism. ( 28710195 )
2017
27
Concomitant Diffuse Alveolar Hemorrhage and Pulmonary Embolism in a Child with Isolated Pulmonary Capillaritis. ( 28248576 )
2017
28
Hybrid method in severe pulmonary embolism not suitable for systemic fibrinolysis. ( 28949255 )
2017
29
Prognostic value of computed tomography pulmonary angiography indices in patients with cancer-related pulmonary embolism: Data from a multicenter cohort study. ( 28065377 )
2017
30
Prevalence of pulmonary embolism in patients presenting to the emergency department with syncope. ( 28811209 )
2017
31
Echocardiographic assessment with right ventricular function improvement following ultrasound-accelerated catheter-directed thrombolytic therapy in submassive pulmonary embolism. ( 28945166 )
2017
32
Treatment of pulmonary embolism with argatroban and ultrasound-assisted catheter-directed thrombolysis with alteplase in a patient with heparin-induced thrombocytopenia. ( 28743779 )
2017
33
To screen or not to screen for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism. ( 28073030 )
2017
34
Lung function, functional capacity, and respiratory symptoms at discharge from hospital in patients with acute pulmonary embolism: A cross-sectional study. ( 28937837 )
2017
35
Acute kidney injury and risk of deep vein thrombosis and pulmonary embolism in Taiwan: A nationwide retrospective cohort study. ( 28092798 )
2017
36
Massive Pulmonary Embolism in Recovery Period of General Anesthesia: Rapid Diagnosis and Successful Rescue by the Guidance of Transthoracic Echocardiography. ( 28091421 )
2017
37
Resuscitation of prolonged cardiac arrest from massive pulmonary embolism by extracorporeal membrane oxygenation. ( 28073853 )
2017
38
Incremental diagnostic quality gain of CTA over V/Q scan in the assessment of pulmonary embolism by means of a Wells score Bayesian model: results from the ACDC collaboration. ( 28236025 )
2017
39
Inferior Vena Cava Filters to Prevent Pulmonary Embolism: Systematic Review andA Meta-Analysis. ( 28935036 )
2017
40
Efficacy and Safety of Thrombolytic Therapy in Acute Submassive Pulmonary Embolism: Follow-Up Study. ( 28090232 )
2017
41
Diagnostic Accuracy of Point-of-Care Ultrasound Performed by Pulmonary Critical Care Physicians for Right Ventricle Assessment in Patients With Acute Pulmonary Embolism. ( 28953498 )
2017
42
Age-adjusted plasma D-Dimer levels in suspected acute pulmonary embolism - a retrospective, single center study. ( 28075426 )
2017
43
Role of chemotherapy and thrombolysis in treatment of choriocarcinoma accompanied with pulmonary embolism: A case report with literature review. ( 28885339 )
2017
44
Death from pulmonary embolism of cyanoacrylate glue following gastric varix endoscopic injection. ( 28091982 )
2017
45
Cardiac metastasis of tongue squamous cell carcinoma complicated by pulmonary embolism: A case report. ( 28700484 )
2017
46
Noise-optimized monoenergetic post-processing improves visualization of incidental pulmonary embolism in cancer patients undergoing single-pass dual-energy computed tomography. ( 28070843 )
2017
47
Pulmonary embolism: An unusual finding during endobronchial sonography. ( 28940622 )
2017
48
Acute pulmonary embolism leading to cavitation and large pulmonary abscess: A rare complication of pulmonary infarction. ( 28066704 )
2017
49
Could Surgical Pulmonary Embolectomy Be Performed With Acceptable Outcomes Without a Pulmonary Embolism Response Team? ( 28935307 )
2017
50
No added value of the age-adjusted D-dimer cut-off to the YEARS algorithm in patients with suspected pulmonary embolism. ( 28941051 )
2017

Variations for Pulmonary Embolism

Expression for Pulmonary Embolism

Search GEO for disease gene expression data for Pulmonary Embolism.

Pathways for Pulmonary Embolism

Pathways related to Pulmonary Embolism according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.97 ALB APOH F10 F2 F3 F5
2
Show member pathways
12.6 F10 F2 F3 F5 F9 SERPINC1
3
Show member pathways
12.07 ALB CRP F2 MTHFR PLAT SERPINE1
4
Show member pathways
11.81 F10 F2 F3 F5 F9 PLAT
5
Show member pathways
11.67 F10 F2 F9
6 11.59 FABP3 TNNI3 TNNT2
7 11.42 F10 F2 F3 F5 F9 PLAT
8 10.72 F10 F2 F9
9 10.61 PLAT SERPINE1 SERPINF2

GO Terms for Pulmonary Embolism

Cellular components related to Pulmonary Embolism according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 9.81 APOH F3 PLAT SERPINE1
2 extracellular region GO:0005576 9.77 ALB APOH CRP F10 F2 F3
3 blood microparticle GO:0072562 9.73 ALB F2 SERPINC1 SERPINF2
4 Golgi lumen GO:0005796 9.67 F10 F2 F9
5 endoplasmic reticulum lumen GO:0005788 9.63 ALB F10 F2 F5 F9 SERPINC1
6 platelet alpha granule lumen GO:0031093 9.56 ALB F5 SERPINE1 SERPINF2
7 troponin complex GO:0005861 9.48 TNNI3 TNNT2
8 cardiac myofibril GO:0097512 9.46 TNNI3 TNNT2
9 extracellular space GO:0005615 9.44 ALB APOH CRP F2 F3 F5
10 intrinsic component of external side of plasma membrane GO:0031233 9.4 F10 F3
11 cardiac Troponin complex GO:1990584 9.37 TNNI3 TNNT2
12 extracellular exosome GO:0070062 10.06 ALB APOH CRP F2 F3 F9

Biological processes related to Pulmonary Embolism according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.85 ALB F2 F5 SERPINC1
2 ER to Golgi vesicle-mediated transport GO:0006888 9.83 F10 F2 F5 F9
3 platelet degranulation GO:0002576 9.8 ALB APOH F5 SERPINE1 SERPINF2
4 negative regulation of peptidase activity GO:0010466 9.77 SERPINC1 SERPINE1 SERPINF2
5 acute-phase response GO:0006953 9.69 CRP F2 SERPINF2
6 regulation of blood coagulation GO:0030193 9.67 APOH F2 SERPINC1
7 signal peptide processing GO:0006465 9.65 F10 F2 F9
8 positive regulation of blood coagulation GO:0030194 9.63 APOH F2 SERPINE1
9 fibrinolysis GO:0042730 9.62 F2 PLAT SERPINE1 SERPINF2
10 peptidyl-glutamic acid carboxylation GO:0017187 9.61 F10 F2 F9
11 regulation of muscle contraction GO:0006937 9.58 TNNI3 TNNT2
12 negative regulation of blood coagulation GO:0030195 9.58 APOH SERPINE1
13 plasminogen activation GO:0031639 9.57 APOH PLAT
14 negative regulation of ATPase activity GO:0032780 9.56 TNNI3 TNNT2
15 blood coagulation, intrinsic pathway GO:0007597 9.56 APOH F10 F2 F9
16 negative regulation of plasminogen activation GO:0010757 9.54 SERPINE1 SERPINF2
17 blood coagulation, extrinsic pathway GO:0007598 9.54 F10 F3 F9
18 blood coagulation GO:0007596 9.5 F10 F2 F3 F5 F9 PLAT
19 negative regulation of fibrinolysis GO:0051918 9.46 APOH F2 SERPINE1 SERPINF2
20 hemostasis GO:0007599 9.1 F10 F2 F3 F5 F9 SERPINC1

Molecular functions related to Pulmonary Embolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase inhibitor activity GO:0030414 9.63 SERPINC1 SERPINE1 SERPINF2
2 serine-type peptidase activity GO:0008236 9.62 F10 F2 F9 PLAT
3 serine-type endopeptidase inhibitor activity GO:0004867 9.58 SERPINC1 SERPINE1 SERPINF2
4 phospholipid binding GO:0005543 9.54 APOH F10 F3
5 fatty acid binding GO:0005504 9.43 ALB FABP3
6 protease binding GO:0002020 9.26 F3 SERPINC1 SERPINE1 SERPINF2
7 troponin C binding GO:0030172 9.16 TNNI3 TNNT2
8 serine-type endopeptidase activity GO:0004252 9.02 F10 F2 F3 F9 PLAT
9 protein binding GO:0005515 10.16 ALB APOH CRP F10 F2 F3

Sources for Pulmonary Embolism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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