MCID: PLM044
MIFTS: 22

Pulmonary Fibrosis, Familial malady

Genetic diseases (common), Respiratory diseases categories

Aliases & Classifications for Pulmonary Fibrosis, Familial

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Pulmonary Fibrosis, Familial, Aliases & Descriptions:

Name: Pulmonary Fibrosis, Familial 19 20
Adult Familial Cryptogenic Fibrosing Alveolitis 19
 
Familial Interstitial Pneumonia 19


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)
Anatomical: Respiratory diseases


Summaries for Pulmonary Fibrosis, Familial

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MalaCards based summary: Pulmonary Fibrosis, Familial, also known as adult familial cryptogenic fibrosing alveolitis, is related to pulmonary fibrosis and pulmonary fibrosis, idiopathic. An important gene associated with Pulmonary Fibrosis, Familial is TERT (telomerase reverse transcriptase), and among its related pathways are Phagosome and Pertussis. The compounds lipofectamine and tin(2+) have been mentioned in the context of this disorder. Related mouse phenotype tumorigenesis.

GeneReviews summary for pf

Related Diseases for Pulmonary Fibrosis, Familial

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Graphical network of the top 20 diseases related to Pulmonary Fibrosis, Familial:



Diseases related to pulmonary fibrosis, familial

Symptoms for Pulmonary Fibrosis, Familial

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Drugs & Therapeutics for Pulmonary Fibrosis, Familial

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Drug clinical trials:

Search ClinicalTrials for Pulmonary Fibrosis, Familial

Search NIH Clinical Center for Pulmonary Fibrosis, Familial

Genetic Tests for Pulmonary Fibrosis, Familial

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Genetic tests related to Pulmonary Fibrosis, Familial:

id Genetic test Affiliating Genes
1 Familial Pulmonary Fibrosis20 TERT

Anatomical Context for Pulmonary Fibrosis, Familial

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Animal Models for Pulmonary Fibrosis, Familial or affiliated genes

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MGI Mouse Phenotypes related to Pulmonary Fibrosis, Familial:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.6SFTPC, TERC, TERT

Publications for Pulmonary Fibrosis, Familial

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Articles related to Pulmonary Fibrosis, Familial:

idTitleAuthorsYear
1
Genetics in pulmonary fibrosis--familial cases provide clues to the pathogenesis of idiopathic pulmonary fibrosis. (21613931)
2011
2
Pulmonary Fibrosis, Familial (20301408)
1993

Variations for Pulmonary Fibrosis, Familial

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Expression for genes affiliated with Pulmonary Fibrosis, Familial

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Search GEO for disease gene expression data for Pulmonary Fibrosis, Familial.

Pathways for genes affiliated with Pulmonary Fibrosis, Familial

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Pathways related to Pulmonary Fibrosis, Familial according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5SFTPA2, SFTPA1
29.5SFTPA2, SFTPA1
3
Show member pathways
FOXA transcription factor networks36
9.5SFTPA2, SFTPA1

Compounds for genes affiliated with Pulmonary Fibrosis, Familial

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Sources:
43Novoseek, 49PharmGKB, 12DrugBank, 24HMDB
See all sources

Compounds related to Pulmonary Fibrosis, Familial according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1lipofectamine439.6TERC, TERT
2tin(2+)439.6TERC, TERT
3zidovudine43 49 1211.6TERT, TERC
4adpribose439.5TERC, TERT
55fluorouracil439.4TERC, TERT
6adriamycin439.3TERC, TERT
7retinoic acid43 249.3SFTPC, TERC, TERT
8calcium43 49 24 1211.3TERT, SFTPA1, SFTPC, SFTPA2

GO Terms for genes affiliated with Pulmonary Fibrosis, Familial

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Cellular components related to Pulmonary Fibrosis, Familial according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1collagenGO:00055819.2SFTPA2, SFTPA1
2extracellular spaceGO:00056158.7SFTPA2, SFTPC, SFTPA1

Biological processes related to Pulmonary Fibrosis, Familial according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1respiratory gaseous exchangeGO:00075858.7SFTPA2, SFTPC, SFTPA1

Molecular functions related to Pulmonary Fibrosis, Familial according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1carbohydrate bindingGO:00302469.5SFTPA2, SFTPA1

Products for genes affiliated with Pulmonary Fibrosis, Familial

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Pulmonary Fibrosis, Familial

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet