MCID: PLM044
MIFTS: 27

Pulmonary Fibrosis, Familial malady

Genetic diseases (common), Respiratory diseases categories
Download this MalaCard

Summaries for Pulmonary Fibrosis, Familial

About this section
Sources:
19GeneReviews, 33MalaCards
See all sources

Fully expand this MalaCard
MalaCards: Pulmonary Fibrosis, Familial, also known as adult familial cryptogenic fibrosing alveolitis, is related to pulmonary fibrosis and idiopathic pulmonary fibrosis. An important gene associated with Pulmonary Fibrosis, Familial is TERT (telomerase reverse transcriptase), and among its related pathways are Phagosome and Pertussis. The compounds lipofectamine and tin(2+) have been mentioned in the context of this disorder. Related mouse phenotype tumorigenesis.

GeneReviews summary for pf

Aliases & Classifications for Pulmonary Fibrosis, Familial

About this section
Sources:
19GeneReviews, 20GeneTests
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)
Anatomical: Respiratory diseases


Aliases & Descriptions:

pulmonary fibrosis, familial 19 20
adult familial cryptogenic fibrosing alveolitis 19
familial interstitial pneumonia 19


Related Diseases for Pulmonary Fibrosis, Familial

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Pulmonary Fibrosis, Familial:



Diseases related to pulmonary fibrosis, familial

Symptoms for Pulmonary Fibrosis, Familial

About this section

Drugs & Therapeutics for Pulmonary Fibrosis, Familial

About this section
Sources:
42NIH Clinical Center, 6ClinicalTrials
See all sources

Drug clinical trials:

Search ClinicalTrials for Pulmonary Fibrosis, Familial

Search NIH Clinical Center for Pulmonary Fibrosis, Familial

Genetic Tests for Pulmonary Fibrosis, Familial

About this section
Sources:
20GeneTests
See all sources

Genetic tests related to Pulmonary Fibrosis, Familial:

id Genetic test Affiliating Genes
1 Familial Pulmonary Fibrosis20 TERT

Anatomical Context for Pulmonary Fibrosis, Familial

About this section

Animal Models for Pulmonary Fibrosis, Familial or affiliated genes

About this section
Sources:
37MGI
See all sources

MGI Mouse Phenotypes related to Pulmonary Fibrosis, Familial:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.6SFTPC, TERC, TERT

Publications for Pulmonary Fibrosis, Familial

About this section
Sources:
52PubMed
See all sources

Articles related to Pulmonary Fibrosis, Familial:

idTitleAuthorsYear
1
Genetics in pulmonary fibrosis--familial cases provide clues to the pathogenesis of idiopathic pulmonary fibrosis. (21613931)
2011
2
Pulmonary Fibrosis, Familial (20301408)
1993

Variations for Pulmonary Fibrosis, Familial

About this section

Expression for genes affiliated with Pulmonary Fibrosis, Familial

About this section
Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Pulmonary Fibrosis, Familial

Search GEO for disease gene expression data for Pulmonary Fibrosis, Familial.

Pathways for genes affiliated with Pulmonary Fibrosis, Familial

About this section
Sources:
50PathCards, 30KEGG, 38NCBI BioSystems Database
See all sources

Pathways related to Pulmonary Fibrosis, Familial according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5SFTPA2, SFTPA1
29.5SFTPA2, SFTPA1
3
Show member pathways
FOXA transcription factor networks38
9.5SFTPA2, SFTPA1

Compounds for genes affiliated with Pulmonary Fibrosis, Familial

About this section
Sources:
45Novoseek, 51PharmGKB, 11DrugBank, 24HMDB
See all sources

Compounds related to Pulmonary Fibrosis, Familial according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1lipofectamine459.6TERC, TERT
2tin(2+)459.6TERC, TERT
3zidovudine45 51 1111.6TERT, TERC
4adpribose459.5TERC, TERT
55fluorouracil459.4TERC, TERT
6adriamycin459.3TERC, TERT
7retinoic acid45 249.3SFTPC, TERC, TERT
8calcium45 51 24 1111.3TERT, SFTPA1, SFTPC, SFTPA2

GO Terms for genes affiliated with Pulmonary Fibrosis, Familial

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Pulmonary Fibrosis, Familial according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1collagenGO:0055819.2SFTPA2, SFTPA1
2extracellular spaceGO:0056158.7SFTPA2, SFTPC, SFTPA1

Biological processes related to Pulmonary Fibrosis, Familial according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1respiratory gaseous exchangeGO:0075858.7SFTPA2, SFTPC, SFTPA1

Molecular functions related to Pulmonary Fibrosis, Familial according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1carbohydrate bindingGO:0302469.5SFTPA2, SFTPA1

Products for genes affiliated with Pulmonary Fibrosis, Familial

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pulmonary Fibrosis, Familial

About this section
4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet