MCID: PLM018
MIFTS: 33

Pulmonary Sclerosing Hemangioma malady

Cancer diseases category
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Summaries for Pulmonary Sclerosing Hemangioma

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33MalaCards
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MalaCards: Pulmonary Sclerosing Hemangioma, also known as pneumocytoma, is related to sclerosing hemangioma and hemangioma. An important gene associated with Pulmonary Sclerosing Hemangioma is NKX2-1 (NK2 homeobox 1), and among its related pathways is Cell adhesion Integrin mediated cell adhesion and migration. The compounds 2,4-dinitrophenol and mucicarmine have been mentioned in the context of this disorder. Affiliated tissues include lung, thyroid and lymph node.

Aliases & Classifications for Pulmonary Sclerosing Hemangioma

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8Disease Ontology, 62UMLS, 35MeSH, 40NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

pulmonary sclerosing hemangioma 8 62
pneumocytoma 8


External Ids:

Disease Ontology8 DOID:5766
MeSH35 D047868
NCIt40 C5656

Related Diseases for Pulmonary Sclerosing Hemangioma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Pulmonary Sclerosing Hemangioma:



Diseases related to pulmonary sclerosing hemangioma

Symptoms for Pulmonary Sclerosing Hemangioma

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Drugs & Therapeutics for Pulmonary Sclerosing Hemangioma

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Pulmonary Sclerosing Hemangioma

Search NIH Clinical Center for Pulmonary Sclerosing Hemangioma

Genetic Tests for Pulmonary Sclerosing Hemangioma

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Anatomical Context for Pulmonary Sclerosing Hemangioma

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33MalaCards
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MalaCards organs/tissues related to Pulmonary Sclerosing Hemangioma:

33
Lung, Thyroid, Lymph node, Kidney, Breast, Fetal lung

Animal Models for Pulmonary Sclerosing Hemangioma or affiliated genes

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Publications for Pulmonary Sclerosing Hemangioma

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52PubMed
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Articles related to Pulmonary Sclerosing Hemangioma:

(show top 50)    (show all 55)
idTitleAuthorsYear
1
Histogenesis of pulmonary sclerosing hemangioma and significance of P63 expression. (23910931)
2013
2
A rare tumor of the lung: pulmonary sclerosing hemangioma (pneumocytoma). (23290153)
2013
3
Pulmonary sclerosing hemangioma: a unique epithelial neoplasm of the lung (report of 26 cases). (23587094)
2013
4
18F-FDG PET/CT features of pulmonary sclerosing hemangioma. (22291338)
2013
5
Synchronous occurrence of breast cancer and pulmonary sclerosing hemangioma: management and review of the literature. (23838116)
2013
6
A case of pulmonary sclerosing hemangioma with low (18)FDG uptake in PET. (22740968)
2012
7
Pulmonary sclerosing hemangioma presenting with dense spindle stroma cells: a potential diagnostic pitfall. (23227905)
2012
8
Pulmonary sclerosing hemangioma: report of two cases. (22943472)
2012
9
Pulmonary sclerosing hemangioma: pitfalls in management. (21471259)
2011
10
Comparison of genetic and epigenetic alterations at 11 tumor suppressor loci in pulmonary sclerosing hemangioma and adenocarcinoma. (21649526)
2011
11
A case of pulmonary sclerosing hemangioma surrounded by giant cystic change on high-resolution computed tomography. (20634757)
2011
12
Pulmonary sclerosing hemangioma in a 21-year-old male with metastatic hereditary non-polyposis colorectal cancer: report of a case. (21645337)
2011
13
Determination of clonal status of pulmonary sclerosing hemangioma with X-chromosome inactivation mosaicism and polymorphism of phosphoglycerate kinase and androgen receptor genes. (20422318)
2011
14
F-18 FDG PET/CT in evaluation of pulmonary sclerosing hemangioma. (21467848)
2011
15
Coexistence of pulmonary sclerosing hemangioma and primary adenocarcinoma in the same nodule of lung. (21599956)
2011
16
Pulmonary sclerosing hemangioma with pleural dissemination: report of a case. (21264765)
2011
17
Surgery for Pulmonary Sclerosing Hemangioma: Lobectomy versus Limited Resection. (22263122)
2011
18
Large masses with diffuse calcification: pulmonary sclerosing hemangioma. (20732478)
2010
19
Cytogenetic study of a pulmonary sclerosing hemangioma. (19837274)
2009
20
Recurrence of pulmonary sclerosing hemangioma. (18278694)
2008
21
Pulmonary sclerosing hemangioma manifesting as a nodule with irregular air clefts on high-resolution CT. (17579131)
2007
22
Expression of E-cadherin, beta-catenin and p120ctn in the pulmonary sclerosing hemangioma. (17383052)
2007
23
Pulmonary sclerosing hemangioma detected by fluorodeoxyglucose positron emission tomography in familial adenomatous polyposis: report of a case. (17473941)
2007
24
Study of androgen receptor and phosphoglycerate kinase gene polymorphism in major cellular components of the so-called pulmonary sclerosing hemangioma]. (16776996)
2006
25
Pulmonary sclerosing hemangioma with pulmonary metastasis. (16902885)
2006
26
Pulmonary sclerosing hemangioma presenting as solitary pulmonary nodule: dynamic CT findings and histopathologic comparisons. (16861548)
2006
27
Proteomic analysis of pulmonary sclerosing hemangioma. (16892484)
2006
28
Bilateral multiple pulmonary sclerosing hemangioma. (15828298)
2005
29
Pulmonary sclerosing hemangioma with metastasis to the mediastinal lymph node. (16305908)
2005
30
Expression patterns of markers for type II pneumocytes in pulmonary sclerosing hemangiomas and fetal lung tissues. (15974816)
2005
31
Expression of the estrogen receptor beta in 37 surgically treated pulmonary sclerosing hemangiomas in comparison with non-small cell lung carcinomas. (16226111)
2005
32
Type-II pneumocyte differentiation in pulmonary sclerosing hemangioma: ultrastructural differentiation and immunohistochemical distribution of lineage-specific transcription factors (TTF-1, HNF-3 alpha, and HNF-3 beta) and surfactant proteins. (15138814)
2004
33
Immunohistochemical and ultrastructural markers suggest different origins for cuboidal and polygonal cells in pulmonary sclerosing hemangioma. (15116333)
2004
34
Pulmonary sclerosing hemangioma associated with familial adenomatous polyposis. (15188145)
2004
35
Pulmonary sclerosing hemangioma with lymph node metastases: report of 4 cases. (12653576)
2003
36
Biologic significance of thyroid transcription factor-1 and surfactant protein expression in pulmonary sclerosing hemangioma]. (14720435)
2003
37
Pulmonary sclerosing hemangioma with lymph node metastases. (14571291)
2003
38
The expression of thyroid transcription factor-1 in pulmonary sclerosing hemangioma and a further investigation on histogenesis of the tumor]. (11955335)
2002
39
Cytopathologic diagnosis of pulmonary sclerosing hemangioma. (11892021)
2002
40
Imprint cytologic features of pulmonary sclerosing hemangioma: comparison with well-differentiated papillary adenocarcinoma. (12115302)
2002
41
A critical examination of the immunophenotype of pulmonary sclerosing hemangioma. (10716159)
2000
42
Pulmonary sclerosing hemangioma consistently expresses thyroid transcription factor-1 (TTF-1): a new clue to its histogenesis. (11075855)
2000
43
A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies: TTF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium. (10895813)
2000
44
Pulmonary sclerosing hemangioma: report of a case with emphasis on dynamic MR imaging findings. (9192438)
1997
45
Pulmonary sclerosing hemangioma in a woman with multiple uterine fibromas, cysts to thyroid and kidney. (8702253)
1996
46
Positive expression of c-myc and p53 products in two cases of pulmonary sclerosing hemangioma]. (8821986)
1995
47
Pulmonary sclerosing hemangioma. Report of a case with diagnosis by fine needle aspiration. (1316026)
1992
48
Pulmonary sclerosing hemangioma: unusual cause of a solitary pulmonary nodule. (2257512)
1990
49
Pulmonary sclerosing hemangioma of the lung. A type II pneumocytoma by immunohistochemical and immunoelectron microscopic studies. (2548701)
1989
50
Pulmonary sclerosing hemangioma: sometimes a form of pulmonary hamartoma. (7089615)
1982

Variations for Pulmonary Sclerosing Hemangioma

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Expression for genes affiliated with Pulmonary Sclerosing Hemangioma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pulmonary Sclerosing Hemangioma

Search GEO for disease gene expression data for Pulmonary Sclerosing Hemangioma.

Pathways for genes affiliated with Pulmonary Sclerosing Hemangioma

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50PathCards, 60Thomson Reuters
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Pathways related to Pulmonary Sclerosing Hemangioma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Cytoskeleton remodeling Fibronectin binding integrins in cell motility60
Cytoskeleton remodeling Integrin outside in signaling60
Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases60
Cell adhesion Tight junctions60
Development MAG dependent inhibition of neurite outgrowth60
9.5NKX2-1, ACTC1

Compounds for genes affiliated with Pulmonary Sclerosing Hemangioma

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45Novoseek, 24HMDB, 29IUPHAR, 61Tocris Bioscience, 11DrugBank, 51PharmGKB
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Compounds related to Pulmonary Sclerosing Hemangioma according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
12,4-dinitrophenol459.7NKX2-1, SFTPB
2mucicarmine459.7NKX2-1, ACTC1
3b 723459.7NKX2-1, ACTC1
4methanol45 2410.5SFTPB, ACTC1
5progesterone45 29 61 24 1113.5ACTC1, SFTPB
6hematoxylin459.5NKX2-1, ACTC1
7formaldehyde45 2410.5NKX2-1, ACTC1
8ribonucleic acid459.2SFTPB, ACTC1, NKX2-1
9paraffin459.1NKX2-1, ACTC1, SFTPB
10dexamethasone45 51 29 1111.9SFTPB, ACTC1, NKX2-1
11retinoic acid45 249.7NKX2-1, ACTC1, SFTPB

GO Terms for genes affiliated with Pulmonary Sclerosing Hemangioma

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16Gene Ontology
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Cellular components related to Pulmonary Sclerosing Hemangioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.8ACTC1, SFTPA1, SFTPB

Biological processes related to Pulmonary Sclerosing Hemangioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1respiratory gaseous exchangeGO:0075859.3SFTPA1, SFTPB

Products for genes affiliated with Pulmonary Sclerosing Hemangioma

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Sources for Pulmonary Sclerosing Hemangioma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet