MCID: PLM064
MIFTS: 27

Pulmonary Sequestration malady

Categories: Rare diseases, Respiratory diseases, Fetal diseases

Aliases & Classifications for Pulmonary Sequestration

Aliases & Descriptions for Pulmonary Sequestration:

Name: Pulmonary Sequestration 50

Classifications:



Summaries for Pulmonary Sequestration

NIH Rare Diseases : 50 pulmonary sequestration is a rare congenital (present from birth) malformation where non-functioning lung tissue is separated from the rest of the lung and supplied with blood from an unusual source, often an artery from systemic circulation. pulmonary sequestrations may be defined as intralobular or extralobular, depending on their location. symptoms may include a chronic  or recurrent cough, respiratory distress or lung infection. treatment depends on the location and may involve surgery. last updated: 8/12/2016

MalaCards based summary : Pulmonary Sequestration is related to congenital pulmonary sequestration and intralobar congenital pulmonary sequestration. An important gene associated with Pulmonary Sequestration is DICER1 (Dicer 1, Ribonuclease III). The drugs Omalizumab and Anti-Allergic Agents have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and neutrophil.

Wikipedia : 71 A pulmonary sequestration (bronchopulmonary sequestration or cystic lung lesion), is a medical condition... more...

Related Diseases for Pulmonary Sequestration

Diseases in the Pulmonary Sequestration family:

Congenital Pulmonary Sequestration

Diseases related to Pulmonary Sequestration via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
id Related Disease Score Top Affiliating Genes
1 congenital pulmonary sequestration 12.1
2 intralobar congenital pulmonary sequestration 11.9
3 extralobar congenital pulmonary sequestration 11.9
4 aneurysm 10.1
5 congenital diaphragmatic hernia 9.9
6 bronchogenic cyst 9.9
7 hydrops fetalis 9.9
8 mediastinitis 9.9
9 lung cancer 9.9
10 diaphragmatic eventration 9.9
11 tuberculosis 9.9
12 aspergillosis 9.9
13 esophagitis 9.9
14 adenocarcinoma 9.8
15 vasculitis 9.7
16 neuroblastoma 9.7
17 aortic aneurysm 9.7
18 pancreatitis 9.7
19 patent ductus arteriosus 9.7
20 ventricular septal defect 9.7
21 cardiomyopathy 9.7
22 congestive heart failure 9.7
23 pheochromocytoma 9.6
24 dilated cardiomyopathy 9.6
25 ischemia 9.6
26 differentiated thyroid carcinoma 9.6
27 leukemia 9.6
28 thymoma 9.6
29 myeloid leukemia 9.6
30 primary ciliary dyskinesia 9.6
31 cerebritis 9.6
32 meckel's diverticulum 9.6
33 immune hydrops fetalis 9.6
34 asthma 9.6
35 fibroma 9.6
36 bronchiectasis 9.6
37 breast cancer 9.6
38 lymphoma 9.6
39 tetralogy of fallot 9.6
40 castleman disease 9.6
41 sarcoma 9.6
42 seminoma 9.6
43 gastric duplication cysts 9.6
44 aicardi syndrome 9.6
45 arteriovenous malformation 9.6
46 laryngomalacia 9.6
47 mitral valve insufficiency 9.6
48 pneumonia 9.6
49 mycobacterium gordonae 9.6
50 duodenal atresia 9.6

Graphical network of the top 20 diseases related to Pulmonary Sequestration:



Diseases related to Pulmonary Sequestration

Symptoms & Phenotypes for Pulmonary Sequestration

Drugs & Therapeutics for Pulmonary Sequestration

Drugs for Pulmonary Sequestration (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Omalizumab Approved, Investigational Phase 4 242138-07-4
2 Anti-Allergic Agents Phase 4
3 Anti-Asthmatic Agents Phase 4
4 Respiratory System Agents Phase 4
5
Hydroxyurea Approved Phase 2 127-07-1 3657
6
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
7
Gemcitabine Approved Phase 2 95058-81-4 60750
8
protease inhibitors Phase 2
9 Serine Proteinase Inhibitors Phase 2
10 Alpha 1-Antitrypsin Phase 2
11 HIV Protease Inhibitors Phase 2
12 Trypsin Inhibitors Phase 2
13 Protein C Phase 2
14 Protein C Inhibitor Phase 2
15 Nucleic Acid Synthesis Inhibitors Phase 2
16 Immunoglobulins Phase 2
17 Antibodies, Monoclonal Phase 2
18 Antibodies Phase 2
19 Albumin-Bound Paclitaxel Phase 2
20 Anti-Infective Agents Phase 2
21 Immunosuppressive Agents Phase 2
22 Antimetabolites Phase 2
23 Antimetabolites, Antineoplastic Phase 2
24 Antimitotic Agents Phase 2
25 Antineoplastic Agents, Phytogenic Phase 2
26 Antiviral Agents Phase 2
27 serine Nutraceutical Phase 2
28
Iron Approved 7439-89-6 23925
29 Trace Elements
30 Micronutrients
31 Pharmaceutical Solutions

Interventional clinical trials:


id Name Status NCT ID Phase
1 Immunologic Basis of Anti-IgE Therapy (Study II: On Patients With Asthma) Completed NCT00367016 Phase 4
2 Safety and Efficacy of Inhaled Alpha-1 Antitrypsin in Preventing Bronchiolitis Obliterable Syndrome in Lung Transplant Recipients Unknown status NCT01394835 Phase 2
3 Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises Completed NCT01895361 Phase 2
4 Nab-pacliatxel Plus Gemcitabine in Korean Patients With Metastatic Pancreatic Ductal Adenocarcinoma Recruiting NCT02426281 Phase 2
5 Cardiopulmonary Circuits in the Pediatric Population Completed NCT00208728
6 Iron Absorption and Utilization During Tuberculosis and After Treatment Completed NCT02176772
7 Congenital Lung Anomalies (CLA) Swiss Database Recruiting NCT03044769
8 Goal-directed Fluid Resuscitation in Acute Pancreatitis Terminated NCT00853515

Search NIH Clinical Center for Pulmonary Sequestration

Genetic Tests for Pulmonary Sequestration

Anatomical Context for Pulmonary Sequestration

MalaCards organs/tissues related to Pulmonary Sequestration:

39
Lung, Heart, Neutrophil, Bone Marrow, Liver, Bone, Myeloid

Publications for Pulmonary Sequestration

Articles related to Pulmonary Sequestration:

(show top 50) (show all 586)
id Title Authors Year
1
Atherosclerosis of aberrant arteries from the left gastric artery into the right intralobar pulmonary sequestration complicated by mycobacterial epithelioid cell granuloma. ( 27776258 )
2017
2
Intralobar pulmonary sequestration in elderly woman: a rare case report with emphasis on imaging findings. ( 27594937 )
2016
3
Isolated subdiaphragmatic extralobar pulmonary sequestration: masquerading as suprarenal mass with spontaneous resolution. ( 27328516 )
2016
4
Extralobar Aneurysm of Intralobar Pulmonary Sequestration Artery Originating From Aorta Arch. ( 27000615 )
2016
5
Necrotizing arteritis occurring in an intralobar pulmonary sequestration of a patient without systemic vasculitis syndrome. ( 26874730 )
2016
6
Pulmonary haemodynamics in Fontan physiology after lobectomy in a patient with a single ventricle associated with pulmonary sequestration. ( 27572898 )
2016
7
Bronchial and Systemic Artery Embolization of Hemorrhagic Adenocarcinoma Arising from a Pulmonary Sequestration. ( 26723930 )
2016
8
Heart Failure in a Preterm Infant. Case Report and Echocardiographic Clues for the Diagnostic Approach to Pulmonary Sequestration. ( 27250095 )
2016
9
Rare presentation of intralobar pulmonary sequestration associated with repeated episodes of ventricular tachycardia. ( 27468336 )
2016
10
Video-assisted thoracic surgery for pulmonary sequestration: a safe alternative procedure. ( 26904209 )
2016
11
Unusual Form of Pulmonary Sequestration: Emphysematous Sequestration. ( 27645986 )
2016
12
Bilateral Intralobar Pulmonary Sequestration With a Bridging Isthmus in a Young Adult. ( 27549558 )
2016
13
EP10.19: Subdiaphragmatic extralobar pulmonary sequestration: report of two cases. ( 27644474 )
2016
14
Mass Effect of Pulmonary Sequestration: Multiloculated-Multiseptated Pneumomediastinum. ( 27123402 )
2016
15
Evaluation of pulmonary sequestration with multidetector computed tomography angiography in a select cohort of patients: A retrospective study. ( 27464296 )
2016
16
Bilateral Intralobar Pulmonary Sequestration in a Young Adult. A Case Report. ( 27818027 )
2016
17
Hemoptysis caused by pulmonary sequestration in perforated appendicitis: A rare case report. ( 28074452 )
2016
18
Presentation and management of pulmonary sequestration with total visceral inflow and outflow. ( 26969317 )
2016
19
Robot-assisted segmental resection for intralobar pulmonary sequestration. ( 27061483 )
2016
20
Short-term outcome of percutaneous treatment of pulmonary sequestration in a pediatric hospital in the Andes: A case series. ( 27470707 )
2016
21
Isolated metastasis of testicular seminoma to extralobar pulmonary sequestration. ( 26744493 )
2016
22
Coil occlusion of aberrant arteries to pulmonary sequestration in a case with pulmonary atresia with intact ventricular septum: successful treatment of repetitive myocardial ischaemic attacks. ( 27702416 )
2016
23
Elevated Carbohydrate Antigen 19-9 Level in a Patient with Horseshoe Type Pulmonary Sequestration. ( 27965928 )
2016
24
Undiagnosed pulmonary sequestration results in an unexplained hemorrhagic shock in thoracoscopic pulmonary lobectomy. ( 27871579 )
2016
25
An Aneurysmal Abdominal Aortic Branch Supplying an Intralobar Pulmonary Sequestration. ( 27000616 )
2016
26
Uniportal thoracoscopic lobectomy for intralobar pulmonary sequestration. ( 26868145 )
2016
27
Intralobar Pulmonary Sequestration With Aneurysmal Feeding Vessel: Use of Hybrid Surgical Management. ( 27847074 )
2016
28
Pulmonary Sequestration: An Unusual Cause of Elevated CA 19-9. ( 27151113 )
2016
29
Extralobar Pulmonary Sequestration with Accompanying Ipsilateral Diaphragmatic Eventration. ( 27670535 )
2016
30
Extralobar pulmonary sequestration in the middle mediastinum. ( 27915420 )
2016
31
Extralobar pulmonary sequestration in neonates: The natural course and predictive factors associated with spontaneous regression. ( 27659701 )
2016
32
Pulmonary sequestration associated with significant elevation of serum carbohydrate antigen 19-9: report of two cases. ( 27826576 )
2016
33
Use of Amplatzer Vascular Plugs for the treatment of combined extralobar and intralobar pulmonary sequestration in a 5-year-old child. ( 27322920 )
2016
34
Endovascular embolization prior to surgical resection of symptomatic intralobar pulmonary sequestration in an adult. ( 27069973 )
2016
35
Extralobar pulmonary sequestration as a cause of recurrent pulmonary hemorrhage in a neonate. ( 26914085 )
2016
36
Congenital diaphragmatic hernia with recurrent gastric volvulus and pulmonary sequestration: A "chance" combination. ( 26862295 )
2016
37
Anomalous systemic arterial supply to the left lower lobe without evidence of pulmonary sequestration. ( 26923779 )
2016
38
Pulmonary sequestration: a case report and literature review. ( 26885149 )
2015
39
Intralobar pulmonary sequestration. ( 25900425 )
2015
40
Congenital pulmonary sequestration supplied by the right coronary artery. ( 26026687 )
2015
41
Intralobar pulmonary sequestration associated with congenital broncho-esophageal fistula. ( 26701956 )
2015
42
Pulmonary Sequestration: A 29 Patient Case Series and Review. ( 26816878 )
2015
43
Primary Pulmonary Sequestration With Secondary Hamartomatosis Change. ( 26528382 )
2015
44
Successful treatment of chronic lower respiratory tract infection by macrolide administration in a patient with intralobar pulmonary sequestration and primary ciliary dyskinesia. ( 26236606 )
2015
45
Extra-lobar Pulmonary Sequestration Requiring Intrauterine Thoracentesis. ( 25628992 )
2015
46
Extralobar pulmonary sequestration with hemorrhagic infarction in a child: preoperative imaging diagnosis and pathological correlation. ( 25995698 )
2015
47
Right intra lobar pulmonary sequestration with feeding artery arising from abdominal aorta: a case report. ( 26109198 )
2015
48
Pulmonary sequestration: A rare case in a patient with acute chest pain and palpitation mimicking the acute coronary syndrome. ( 25624605 )
2015
49
Diagnosis of pulmonary sequestration: Contribution of the CT scan. ( 26375753 )
2015
50
A Case Report and a Short Literature Review of Pulmonary Sequestration Showing Elevated Serum Levels of Carbohydrate Antigen 19-9. ( 26328799 )
2015

Variations for Pulmonary Sequestration

Expression for Pulmonary Sequestration

Search GEO for disease gene expression data for Pulmonary Sequestration.

Pathways for Pulmonary Sequestration

GO Terms for Pulmonary Sequestration

Sources for Pulmonary Sequestration

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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