MCID: PLM071
MIFTS: 27

Pulmonary Surfactant Metabolism Dysfunction malady

Genetic diseases, Metabolic diseases, Respiratory diseases, Rare diseases categories

Summaries for Pulmonary Surfactant Metabolism Dysfunction

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MalaCards based summary: Pulmonary Surfactant Metabolism Dysfunction is related to abca3-related pulmonary surfactant metabolism dysfunction and sftpb-related pulmonary surfactant metabolism dysfunction. An important gene associated with Pulmonary Surfactant Metabolism Dysfunction is SFTPC (surfactant protein C). The compounds infasurf and popg have been mentioned in the context of this disorder. Related mouse phenotype respiratory system.

Aliases & Classifications for Pulmonary Surfactant Metabolism Dysfunction

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Pulmonary Surfactant Metabolism Dysfunction, Aliases & Descriptions:

Name: Pulmonary Surfactant Metabolism Dysfunction 21 23 61


Classifications:



Related Diseases for Pulmonary Surfactant Metabolism Dysfunction

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Diseases in the Surfactant Metabolism Dysfunction, Pulmonary, 1 family:

pulmonary surfactant metabolism dysfunction Abca3-Related Pulmonary Surfactant Metabolism Dysfunction
Sftpb-Related Pulmonary Surfactant Metabolism Dysfunction Sftpc-Related Pulmonary Surfactant Metabolism Dysfunction
Csf2ra-Related Pulmonary Surfactant Metabolism Dysfunction Surfactant Metabolism Dysfunction, Pulmonary, 2
Surfactant Metabolism Dysfunction, Pulmonary, 3 Surfactant Metabolism Dysfunction, Pulmonary, 5
Surfactant Metabolism Dysfunction, Pulmonary, 4

Diseases related to Pulmonary Surfactant Metabolism Dysfunction via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 25)
idRelated DiseaseScoreTop Affiliating Genes
1abca3-related pulmonary surfactant metabolism dysfunction10.4
2sftpb-related pulmonary surfactant metabolism dysfunction10.4
3sftpc-related pulmonary surfactant metabolism dysfunction10.4
4csf2ra-related pulmonary surfactant metabolism dysfunction10.4
5surfactant dysfunction10.4
6surfactant metabolism dysfunction, pulmonary, 110.4
7surfactant metabolism dysfunction, pulmonary, 210.3
8surfactant metabolism dysfunction, pulmonary, 310.3
9surfactant metabolism dysfunction, pulmonary, 510.3
10surfactant metabolism dysfunction, pulmonary, 410.3
11idiopathic pulmonary alveolar proteinosis10.3
12large cell carcinoma10.1SFTPC, SFTPB
13interstitial lung disease10.1SFTPC, SFTPB
14adult respiratory distress syndrome10.1SFTPC, SFTPB
15pulmonary hypertension10.0SFTPB, SFTPC
16idiopathic pulmonary fibrosis10.0SFTPB, SFTPC
17non-small cell lung carcinoma10.0SFTPC, SFTPB
18lung benign neoplasm10.0SFTPB, SFTPC
19pneumonia10.0SFTPC, SFTPB
20lung cancer10.0SFTPB, SFTPC
21lung adenocarcinoma9.9SFTPC, SFTPB
22respiratory failure9.9ABCA3, SFTPB, SFTPC
23cork-handlers' disease9.9ABCA3, SFTPC, SFTPB
24cystic fibrosis9.8SFTPB, SFTPC
25pulmonary alveolar proteinosis9.7CSF2RA, SFTPC, SFTPB

Graphical network of the top 20 diseases related to Pulmonary Surfactant Metabolism Dysfunction:



Diseases related to pulmonary surfactant metabolism dysfunction

Symptoms for Pulmonary Surfactant Metabolism Dysfunction

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Drugs & Therapeutics for Pulmonary Surfactant Metabolism Dysfunction

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Drug clinical trials:

Search ClinicalTrials for Pulmonary Surfactant Metabolism Dysfunction

Search NIH Clinical Center for Pulmonary Surfactant Metabolism Dysfunction

Genetic Tests for Pulmonary Surfactant Metabolism Dysfunction

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Genetic tests related to Pulmonary Surfactant Metabolism Dysfunction:

id Genetic test Affiliating Genes
1 Pulmonary Surfactant Metabolism Dysfunction21 23 SFTPC

Anatomical Context for Pulmonary Surfactant Metabolism Dysfunction

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Animal Models for Pulmonary Surfactant Metabolism Dysfunction or affiliated genes

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MGI Mouse Phenotypes related to Pulmonary Surfactant Metabolism Dysfunction:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.8SFTPC, SFTPB, ABCA3

Publications for Pulmonary Surfactant Metabolism Dysfunction

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Variations for Pulmonary Surfactant Metabolism Dysfunction

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Expression for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

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Expression patterns in normal tissues for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

Search GEO for disease gene expression data for Pulmonary Surfactant Metabolism Dysfunction.

Pathways for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

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Compounds for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

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Compounds related to Pulmonary Surfactant Metabolism Dysfunction according to GeneCards/GeneDecks:

(show all 27)
idCompoundScoreTop Affiliating Genes
1infasurf449.7SFTPC, SFTPB
2popg449.7SFTPB, SFTPC
31,2-dipalmitoyl-sn-glycero-3-phosphocholine449.7SFTPB, SFTPC
4dppg449.7SFTPB, SFTPC
5curosurf449.7SFTPC, SFTPB
6survanta449.7SFTPB, SFTPC
7dopc449.7SFTPB, SFTPC
8dppc449.7SFTPC, SFTPB
9p-opc449.7SFTPB, SFTPC
10butanol449.7SFTPB, SFTPC
11chloroform449.6SFTPC, SFTPB
12methanol44 2510.6SFTPC, SFTPB
13isoleucine449.6SFTPC, SFTPB
14doxycycline44 1210.6SFTPB, SFTPC
15peroxynitrite449.6SFTPC, SFTPB
16bleomycin44 1210.6SFTPC, SFTPB
17palmitate449.6SFTPC, SFTPB
18ibmx44 60 2911.6SFTPB, SFTPC
19phosphatidylcholine449.5SFTPC, SFTPB
20chloramphenicol44 3 50 1212.5SFTPB, SFTPC
21ribonucleic acid449.4SFTPC, SFTPB
22fibrinogen449.4SFTPC, SFTPB
23phospholipid449.3SFTPB, SFTPC
24fatty acid449.3SFTPC, SFTPB
25actinomycin d449.2SFTPC, SFTPB
26hydrogen44 2510.0SFTPC, SFTPB
27lipid449.0SFTPC, SFTPB, ABCA3

GO Terms for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

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Cellular components related to Pulmonary Surfactant Metabolism Dysfunction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1alveolar lamellar bodyGO:0972089.1SFTPC, ABCA3
2extracellular spaceGO:0056158.8SFTPC, SFTPB, ABCA3

Biological processes related to Pulmonary Surfactant Metabolism Dysfunction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to glucocorticoidGO:0513849.4SFTPC, ABCA3
2respiratory gaseous exchangeGO:0075859.0SFTPC, SFTPB

Products for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Pulmonary Surfactant Metabolism Dysfunction

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet