MCID: PLM071
MIFTS: 27

Pulmonary Surfactant Metabolism Dysfunction malady

Genetic diseases, Metabolic diseases, Respiratory diseases, Rare diseases categories
Download this MalaCard

Summaries for Pulmonary Surfactant Metabolism Dysfunction

About this section


Fully expand this MalaCard
MalaCards based summary: Pulmonary Surfactant Metabolism Dysfunction is related to abca3-related pulmonary surfactant metabolism dysfunction and sftpb-related pulmonary surfactant metabolism dysfunction. An important gene associated with Pulmonary Surfactant Metabolism Dysfunction is SFTPC (surfactant protein C). The compounds infasurf and popg have been mentioned in the context of this disorder. Related mouse phenotype respiratory system.

Aliases & Classifications for Pulmonary Surfactant Metabolism Dysfunction

About this section

Pulmonary Surfactant Metabolism Dysfunction, Aliases & Descriptions:

Name: Pulmonary Surfactant Metabolism Dysfunction 20 22 62


Classifications:



Related Diseases for Pulmonary Surfactant Metabolism Dysfunction

About this section

Diseases in the Surfactant Metabolism Dysfunction, Pulmonary, 1 family:

pulmonary surfactant metabolism dysfunction Abca3-Related Pulmonary Surfactant Metabolism Dysfunction
Sftpb-Related Pulmonary Surfactant Metabolism Dysfunction Sftpc-Related Pulmonary Surfactant Metabolism Dysfunction
Csf2ra-Related Pulmonary Surfactant Metabolism Dysfunction Surfactant Metabolism Dysfunction, Pulmonary, 2
Surfactant Metabolism Dysfunction, Pulmonary, 3 Surfactant Metabolism Dysfunction, Pulmonary, 5
Surfactant Metabolism Dysfunction, Pulmonary, 4

Diseases related to Pulmonary Surfactant Metabolism Dysfunction via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 25)
idRelated DiseaseScoreTop Affiliating Genes
1abca3-related pulmonary surfactant metabolism dysfunction10.4
2sftpb-related pulmonary surfactant metabolism dysfunction10.4
3sftpc-related pulmonary surfactant metabolism dysfunction10.4
4csf2ra-related pulmonary surfactant metabolism dysfunction10.4
5surfactant dysfunction10.4
6surfactant metabolism dysfunction, pulmonary, 110.4
7surfactant metabolism dysfunction, pulmonary, 210.3
8surfactant metabolism dysfunction, pulmonary, 310.3
9surfactant metabolism dysfunction, pulmonary, 510.3
10surfactant metabolism dysfunction, pulmonary, 410.3
11idiopathic pulmonary alveolar proteinosis10.3
12large cell carcinoma10.1SFTPC, SFTPB
13interstitial lung disease10.1SFTPC, SFTPB
14adult respiratory distress syndrome10.1SFTPB, SFTPC
15pulmonary hypertension10.0SFTPC, SFTPB
16idiopathic pulmonary fibrosis10.0SFTPC, SFTPB
17non-small cell lung carcinoma10.0SFTPB, SFTPC
18lung benign neoplasm10.0SFTPC, SFTPB
19pneumonia10.0SFTPC, SFTPB
20lung cancer10.0SFTPC, SFTPB
21lung adenocarcinoma9.9SFTPB, SFTPC
22respiratory failure9.9ABCA3, SFTPB, SFTPC
23cork-handlers' disease9.9ABCA3, SFTPB, SFTPC
24cystic fibrosis9.8SFTPB, SFTPC
25pulmonary alveolar proteinosis9.7CSF2RA, SFTPC, SFTPB

Graphical network of the top 20 diseases related to Pulmonary Surfactant Metabolism Dysfunction:



Diseases related to pulmonary surfactant metabolism dysfunction

Symptoms for Pulmonary Surfactant Metabolism Dysfunction

About this section

Drugs & Therapeutics for Pulmonary Surfactant Metabolism Dysfunction

About this section

Drug clinical trials:

Search ClinicalTrials for Pulmonary Surfactant Metabolism Dysfunction

Search NIH Clinical Center for Pulmonary Surfactant Metabolism Dysfunction

Genetic Tests for Pulmonary Surfactant Metabolism Dysfunction

About this section

Genetic tests related to Pulmonary Surfactant Metabolism Dysfunction:

id Genetic test Affiliating Genes
1 Pulmonary Surfactant Metabolism Dysfunction20 22 SFTPC

Anatomical Context for Pulmonary Surfactant Metabolism Dysfunction

About this section

Animal Models for Pulmonary Surfactant Metabolism Dysfunction or affiliated genes

About this section

MGI Mouse Phenotypes related to Pulmonary Surfactant Metabolism Dysfunction:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.8SFTPC, SFTPB, ABCA3

Publications for Pulmonary Surfactant Metabolism Dysfunction

About this section

Variations for Pulmonary Surfactant Metabolism Dysfunction

About this section

Expression for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

About this section
Expression patterns in normal tissues for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

Search GEO for disease gene expression data for Pulmonary Surfactant Metabolism Dysfunction.

Pathways for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

About this section

Compounds for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

About this section

Compounds related to Pulmonary Surfactant Metabolism Dysfunction according to GeneCards/GeneDecks:

(show all 27)
idCompoundScoreTop Affiliating Genes
1infasurf449.7SFTPC, SFTPB
2popg449.7SFTPB, SFTPC
31,2-dipalmitoyl-sn-glycero-3-phosphocholine449.7SFTPB, SFTPC
4dppg449.7SFTPB, SFTPC
5curosurf449.7SFTPC, SFTPB
6survanta449.7SFTPB, SFTPC
7dopc449.7SFTPB, SFTPC
8dppc449.7SFTPC, SFTPB
9p-opc449.7SFTPB, SFTPC
10butanol449.7SFTPB, SFTPC
11chloroform449.6SFTPC, SFTPB
12methanol44 2410.6SFTPC, SFTPB
13isoleucine449.6SFTPC, SFTPB
14doxycycline44 1110.6SFTPB, SFTPC
15peroxynitrite449.6SFTPC, SFTPB
16bleomycin44 1110.6SFTPC, SFTPB
17palmitate449.6SFTPC, SFTPB
18ibmx44 61 2811.6SFTPB, SFTPC
19phosphatidylcholine449.5SFTPC, SFTPB
20chloramphenicol44 2 50 1112.5SFTPB, SFTPC
21ribonucleic acid449.4SFTPC, SFTPB
22fibrinogen449.4SFTPC, SFTPB
23phospholipid449.3SFTPB, SFTPC
24fatty acid449.3SFTPC, SFTPB
25actinomycin d449.2SFTPC, SFTPB
26hydrogen44 2410.0SFTPC, SFTPB
27lipid449.0SFTPC, SFTPB, ABCA3

GO Terms for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

About this section

Cellular components related to Pulmonary Surfactant Metabolism Dysfunction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1alveolar lamellar bodyGO:0972089.1SFTPC, ABCA3
2extracellular spaceGO:0056158.8SFTPC, SFTPB, ABCA3

Biological processes related to Pulmonary Surfactant Metabolism Dysfunction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to glucocorticoidGO:0513849.4SFTPC, ABCA3
2respiratory gaseous exchangeGO:0075859.0SFTPC, SFTPB

Products for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Pulmonary Surfactant Metabolism Dysfunction

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet