MCID: PLM071
MIFTS: 24

Pulmonary Surfactant Metabolism Dysfunction malady

Genetic diseases (common), Metabolic diseases categories

Aliases & Classifications for Pulmonary Surfactant Metabolism Dysfunction

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Aliases & Descriptions for Pulmonary Surfactant Metabolism Dysfunction:

Name: Pulmonary Surfactant Metabolism Dysfunction 20 22
 
Surfactant Dysfunction 61


Classifications:



Summaries for Pulmonary Surfactant Metabolism Dysfunction

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MalaCards based summary: Pulmonary Surfactant Metabolism Dysfunction, also known as surfactant dysfunction, is related to abca3-related pulmonary surfactant metabolism dysfunction and sftpb-related pulmonary surfactant metabolism dysfunction. An important gene associated with Pulmonary Surfactant Metabolism Dysfunction is SFTPC (surfactant protein C). The compounds infasurf and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine have been mentioned in the context of this disorder. Related mouse phenotype respiratory system.

Related Diseases for Pulmonary Surfactant Metabolism Dysfunction

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Diseases in the Pulmonary Surfactant Metabolism Dysfunction family:

Surfactant Metabolism Dysfunction, Pulmonary, 1 Surfactant Metabolism Dysfunction, Pulmonary, 2
Surfactant Metabolism Dysfunction, Pulmonary, 3 Surfactant Metabolism Dysfunction, Pulmonary, 5
Surfactant Metabolism Dysfunction, Pulmonary, 4 Abca3-Related Pulmonary Surfactant Metabolism Dysfunction
Sftpb-Related Pulmonary Surfactant Metabolism Dysfunction Sftpc-Related Pulmonary Surfactant Metabolism Dysfunction
Csf2ra-Related Pulmonary Surfactant Metabolism Dysfunction

Diseases related to Pulmonary Surfactant Metabolism Dysfunction via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
idRelated DiseaseScoreTop Affiliating Genes
1abca3-related pulmonary surfactant metabolism dysfunction10.5
2sftpb-related pulmonary surfactant metabolism dysfunction10.5
3sftpc-related pulmonary surfactant metabolism dysfunction10.5
4csf2ra-related pulmonary surfactant metabolism dysfunction10.5
5surfactant metabolism dysfunction, pulmonary, 110.3
6surfactant metabolism dysfunction, pulmonary, 210.3
7surfactant metabolism dysfunction, pulmonary, 310.3
8surfactant metabolism dysfunction, pulmonary, 510.3
9surfactant metabolism dysfunction, pulmonary, 410.3
10surfactant dysfunction10.3
11large cell carcinoma10.1SFTPC, SFTPB
12interstitial lung disease10.1SFTPC, SFTPB
13acute respiratory distress syndrome10.0SFTPC, SFTPB
14pulmonary hypertension10.0SFTPB, SFTPC
15pulmonary fibrosis, idiopathic10.0SFTPB, SFTPC
16lung benign neoplasm10.0SFTPB, SFTPC
17pneumonia10.0SFTPC, SFTPB
18lung cancer10.0SFTPB, SFTPC
19lung cancer susceptibility 39.9SFTPC, SFTPB
20respiratory failure9.8ABCA3, SFTPB, SFTPC
21cork-handlers' disease9.8ABCA3, SFTPC, SFTPB
22cystic fibrosis9.8SFTPB, SFTPC
23pulmonary alveolar proteinosis9.7CSF2RA, SFTPC, SFTPB

Graphical network of the top 20 diseases related to Pulmonary Surfactant Metabolism Dysfunction:



Diseases related to pulmonary surfactant metabolism dysfunction

Symptoms for Pulmonary Surfactant Metabolism Dysfunction

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Drugs & Therapeutics for Pulmonary Surfactant Metabolism Dysfunction

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Drug clinical trials:

Search ClinicalTrials for Pulmonary Surfactant Metabolism Dysfunction

Search NIH Clinical Center for Pulmonary Surfactant Metabolism Dysfunction

Genetic Tests for Pulmonary Surfactant Metabolism Dysfunction

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Genetic tests related to Pulmonary Surfactant Metabolism Dysfunction:

id Genetic test Affiliating Genes
1 Pulmonary Surfactant Metabolism Dysfunction20 22 SFTPC

Anatomical Context for Pulmonary Surfactant Metabolism Dysfunction

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Animal Models for Pulmonary Surfactant Metabolism Dysfunction or affiliated genes

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MGI Mouse Phenotypes related to Pulmonary Surfactant Metabolism Dysfunction:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.8SFTPC, SFTPB, ABCA3

Publications for Pulmonary Surfactant Metabolism Dysfunction

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Variations for Pulmonary Surfactant Metabolism Dysfunction

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Expression for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

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Search GEO for disease gene expression data for Pulmonary Surfactant Metabolism Dysfunction.

Pathways for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

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Compounds for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

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Compounds related to Pulmonary Surfactant Metabolism Dysfunction according to GeneCards Suite gene sharing:

(show all 27)
idCompoundScoreTop Affiliating Genes
1infasurf449.7SFTPB, SFTPC
21,2-dipalmitoyl-sn-glycero-3-phosphocholine449.7SFTPC, SFTPB
3popg449.7SFTPC, SFTPB
4dppg449.7SFTPB, SFTPC
5curosurf449.7SFTPC, SFTPB
6dopc449.7SFTPC, SFTPB
7survanta449.7SFTPB, SFTPC
8dppc449.7SFTPB, SFTPC
9butanol449.7SFTPC, SFTPB
10p-opc449.7SFTPC, SFTPB
11chloroform449.6SFTPC, SFTPB
12methanol44 2410.6SFTPC, SFTPB
13isoleucine449.6SFTPB, SFTPC
14doxycycline44 1110.6SFTPB, SFTPC
15peroxynitrite449.6SFTPB, SFTPC
16bleomycin44 1110.6SFTPB, SFTPC
17palmitate449.6SFTPB, SFTPC
18ibmx44 60 2811.6SFTPC, SFTPB
19phosphatidylcholine449.5SFTPB, SFTPC
20chloramphenicol44 1 50 1112.5SFTPC, SFTPB
21ribonucleic acid449.4SFTPC, SFTPB
22fibrinogen449.4SFTPB, SFTPC
23phospholipid449.3SFTPC, SFTPB
24fatty acid449.3SFTPC, SFTPB
25actinomycin d449.2SFTPB, SFTPC
26hydrogen44 2410.0SFTPC, SFTPB
27lipid449.0SFTPC, SFTPB, ABCA3

GO Terms for genes affiliated with Pulmonary Surfactant Metabolism Dysfunction

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Cellular components related to Pulmonary Surfactant Metabolism Dysfunction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1alveolar lamellar bodyGO:00972089.1SFTPC, ABCA3
2extracellular spaceGO:00056158.8SFTPC, SFTPB, ABCA3

Biological processes related to Pulmonary Surfactant Metabolism Dysfunction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to glucocorticoidGO:00513849.4SFTPC, ABCA3
2respiratory gaseous exchangeGO:00075859.0SFTPC, SFTPB

Sources for Pulmonary Surfactant Metabolism Dysfunction

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet