MCID: PLM001
MIFTS: 60

Pulmonary Tuberculosis malady

Respiratory diseases category

Summaries for Pulmonary Tuberculosis

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Disease Ontology:9 A tuberculosis that is a contagious disease located in lungs. the infection has symptom fever, has symptom cough, has symptom difficulty in breathing, has symptom inflammatory infiltrations, has symptom formation of tubercles, has symptom caseation, has symptom pleural effusion, and has symptom fibrosis.

MalaCards based summary: Pulmonary Tuberculosis, also known as tuberculosis, pulmonary, is related to leprosy and tuberculosis, and has symptoms including fever, cough and difficulty in breathing. An important gene associated with Pulmonary Tuberculosis is SLC11A1 (solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1), and among its related pathways are Cellular Transformation by HTLV1 and Type II interferon signaling (IFNG). The compounds cellulose acetate and deferoxamine have been mentioned in the context of this disorder. Affiliated tissues include lungs, lung and kidney, and related mouse phenotypes are tumorigenesis and hematopoietic system.

Aliases & Classifications for Pulmonary Tuberculosis

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Pulmonary Tuberculosis, Aliases & Descriptions:

Name: Pulmonary Tuberculosis 9
Tuberculosis, Pulmonary 60
 
Tuberculosis Pulmonary 43
Ptb 37


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


External Ids:

Disease Ontology9 DOID:2957
ICD9CM27 011.9, 011, 011.90
MeSH33 D014397
NCIt38 C26899

Related Diseases for Pulmonary Tuberculosis

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Diseases related to Pulmonary Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 200)
idRelated DiseaseScoreTop Affiliating Genes
1leprosy31.4SLC11A1
2tuberculosis31.0SLC11A1, SP110, TLR1, IRGM, ADA, IFNGR1
3pleurisy30.9ADA
4aspergillosis30.8IFNG, SFTPA2
5pleural tuberculosis30.6IFNG, ADA
6crohn's disease30.5IRGM
7arthritis30.5IFNG, HP, SLC11A1
8pulmonary sarcoidosis30.5IL12B, IFNG
9schistosomiasis30.3IFNGR1, IFNG
10hiv-130.3HP, IL12B, ADA, HLA-S
11leishmaniasis30.3SLC11A1, IFNG, IFNGR1
12lymphopenia30.3IFNG, ADA
13rheumatoid arthritis30.2ADA, IFNG, IL12B, HP, SLC11A1
14atopy30.1SLC11A1, IL12B, IFNG
15hepatitis c30.1IFNG, IL12B, HP
16systemic lupus erythematosus29.9ADA, IFNGR1, IFNG, IL12B
17asthma29.8TLR1, IFNG, IL12B, SLC11A1
18pneumonia10.6
19hepatitis10.5
20lung cancer10.5
21brucellosis10.5SLC11A1
22laryngitis10.5
23omenn syndrome10.4ADA
24intestinal tuberculosis10.4
25silicosis10.4
26miliary tuberculosis10.4
27allergic bronchopulmonary aspergillosis10.4
28cor pulmonale10.4
29typhoid fever10.4SLC11A1, IFNGR1
30prolymphocytic leukemia10.3HLA-S, ADA
31visceral leishmaniasis10.3SLC11A1, IFNG
32drug-induced hepatitis10.3
33anthracosis10.3
34paracoccidioidomycosis10.3
35retinitis10.3
36bronchogenic carcinoma10.3
37plasmodium falciparum malaria10.3HP, IFNG
38chronic granulomatous disease10.2ADA, IFNG
39cork-handlers' disease10.2IFNGR1, HP, SLC11A1
40pulmonary function10.2
41glomerulonephritis10.2
42tuberculoid leprosy10.2
43lepromatous leprosy10.2
44nocardiosis10.2
45paragonimiasis10.2
46asbestosis10.2
47hypercalcemia10.2
48lymph node tuberculosis10.2
49bronchial disease10.2
50mediastinitis10.2

Graphical network of the top 20 diseases related to Pulmonary Tuberculosis:



Diseases related to pulmonary tuberculosis

Symptoms for Pulmonary Tuberculosis

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Symptoms:

 9 (show all 8)
  • fever
  • cough
  • difficulty in breathing
  • inflammatory infiltrations
  • formation of tubercles
  • caseation
  • pleural effusion
  • fibrosis

Drugs & Therapeutics for Pulmonary Tuberculosis

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Drug clinical trials:

Search ClinicalTrials for Pulmonary Tuberculosis

Search NIH Clinical Center for Pulmonary Tuberculosis

Genetic Tests for Pulmonary Tuberculosis

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Anatomical Context for Pulmonary Tuberculosis

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MalaCards organs/tissues related to Pulmonary Tuberculosis:

31
Lung, Kidney, T cells, B cells, Testes, Liver, Neutrophil, Monocytes, Pancreas, Prostate, Brain, Breast, Skin, Eye, Smooth muscle, Adipocyte, Lymph node, Whole blood, Heart, Nk cells, Bone, Spinal cord, Tongue

FMA organs/tissues related to Pulmonary Tuberculosis:

14
Lungs

Animal Models for Pulmonary Tuberculosis or affiliated genes

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MGI Mouse Phenotypes related to Pulmonary Tuberculosis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.7IFNGR1, IFNG, IL12B, HP, SLC11A1
2MP:00053978.3SLC11A1, HP, IL12B, IFNG, IFNGR1, ADA
3MP:00053877.9SLC11A1, TLR1, IRGM, ADA, IFNGR1, IFNG

Publications for Pulmonary Tuberculosis

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Articles related to Pulmonary Tuberculosis:

(show top 50)    (show all 1080)
idTitleAuthorsYear
1
Spoligotype patterns of Mycobacterium tuberculosis isolated from extra pulmonary tuberculosis patients in Puducherry, India. (25865980)
2015
2
Diagnostic Value of Serum Adenosine Deaminase (ADA) Level for Pulmonary Tuberculosis. (25861440)
2015
3
The CD4+/CD8+ Ratio in Pulmonary Tuberculosis: Systematic and Meta-Analysis Article. (25905052)
2015
4
Pulmonary hemorrhage complicating Goodpasture's disease in the course of pulmonary tuberculosis. (22826144)
2013
5
Diagnostic Utility of QuantiFERON-TB Gold In-Tube in active pulmonary tuberculosis in Nigeria. (24122682)
2013
6
Active Case Finding of Pulmonary Tuberculosis through Screening of Respiratory Symptomatics Using Sputum Microscopy: Is It Time to Change the Paradigm? (23533747)
2013
7
Nitric oxide, carbonyl protein, lipid peroxidation and correlation between antioxidant vitamins in different categories of pulmonary and extra pulmonary tuberculosis. (23613657)
2013
8
Active pulmonary tuberculosis and latent tuberculosis infection among homeless people in Seoul, South Korea: a cross-sectional study. (23914947)
2013
9
Target prioritization and strategy selection for active case-finding of pulmonary tuberculosis: a tool to support country-level project planning. (23374118)
2013
10
Potential association of pulmonary tuberculosis with genetic polymorphisms of toll-like receptor 9 and interferon-gamma in a Chinese population. (24176007)
2013
11
Prevalence of multidrug resistance among retreatment pulmonary tuberculosis cases in a tertiary care hospital, Hyderabad, India. (24339482)
2013
12
A systematic review of the association between pulmonary tuberculosis and the development of chronic airflow obstruction in adults. (23652030)
2013
13
Efficacy and safety of recombinant Mycobacterium tuberculosis ESAT-6 protein for diagnosis of pulmonary tuberculosis: a phase II trial. (24217560)
2013
14
Epidemiology of extra-pulmonary tuberculosis in Israel, 1999-2010. (23317959)
2013
15
A cross-sectional study of sputum handling by and supervision of patients with pulmonary tuberculosis treated at home in China. (23337789)
2012
16
Cytokine-secreting activity of blood eosinophils in pulmonary tuberculosis. (22866301)
2012
17
Pulmonary tuberculosis mimicking metastasis in a patient with osteosarcoma. (22935666)
2012
18
Multidrug-resistant pulmonary tuberculosis: surgical challenges. (22789592)
2012
19
Primary and acquired pyrazinamide resistance in patients with pulmonary tuberculosis treated at a referral hospital in the city of Recife, Brazil. (23288119)
2012
20
Rapid molecular diagnosis of pulmonary tuberculosis in children using nasopharyngeal specimens. (22752518)
2012
21
Independent association of younger age with hemoptysis in adults with pulmonary tuberculosis. (22583746)
2012
22
Pulmonary tuberculosis associated retinal vasculitis presenting as xanthopsia. (21428751)
2011
23
Relationship between single nucleotide polymorphism of interleukin-18 and susceptibility to pulmonary tuberculosis in the Chinese Han population. (21395662)
2011
24
Prevalence of multidrug-resistant tuberculosis among newly diagnosed cases of sputum-positive pulmonary tuberculosis. (21441685)
2011
25
Differential combination of cytokine and interferon- I^ +874 T/A polymorphisms determines disease severity in pulmonary tuberculosis. (22140472)
2011
26
Trends and predictors of changes in pulmonary function after treatment for pulmonary tuberculosis. (21655745)
2011
27
Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, and West Africans. (19771452)
2010
28
FDG-PET/CT in diagnosis and early response evaluation of extra-pulmonary tuberculosis in a patient with aplastic anemia. (20739773)
2010
29
Cardiac sarcoidosis: recurrent disease in a heart transplant patient following pulmonary tuberculosis infection. (20847976)
2010
30
Genetic polymorphism of glutathione-S-transferase M1 and T1: a systematic review in Chinese population and a pilot study in smear-positive pulmonary tuberculosis cases of Jilin province]. (19799150)
2009
31
NOS2A, TLR4, and IFNGR1 interactions influence pulmonary tuberculosis susceptibility in African-Americans. (19575238)
2009
32
Oral paracoccidioidomycosis and pulmonary tuberculosis co-infection: relevance of oral biopsy in establishing the diagnosis and therapeutic approach. (18650110)
2009
33
Simultaneous occurrence of pulmonary tuberculosis and carcinomatous lymphangitis. (17486260)
2007
34
Vitamin D receptor gene polymorphisms and sputum conversion time in pulmonary tuberculosis patients. (17449323)
2007
35
Morphometric analysis of Th(1) and Th(2) cytokine expression in human pulmonary tuberculosis. (15525561)
2004
36
Monocyte cytokine secretion in patients with pulmonary tuberculosis differs from that of healthy infected subjects and correlates with clinical manifestations. (14738890)
2004
37
Allelic distribution of human leukocyte antigen in Iranian patients with pulmonary tuberculosis. (12507823)
2003
38
Prediction of the effectiveness of preoperative preparation of patients with fibro-cavernous pulmonary tuberculosis]. (12774420)
2003
39
Circulating levels of stromal cell-derived factor 1alpha and interleukin 7 in HIV type 1 infection and pulmonary tuberculosis are reciprocally related to CXCR4 expression on peripheral blood leukocytes. (12882655)
2003
40
Deep venous thrombosis associated with pulmonary tuberculosis and transient protein S deficiency. (12069029)
2002
41
HLA-DR2 subtypes & immune responses in pulmonary tuberculosis. (11558319)
2001
42
Use of systemic immunomodulator xymedone in distructive pulmonary tuberculosis]. (10900981)
2000
43
Changes in the production of interleukin-1 beta, tumor necrosis factor-alpha and interleukin-2 in relation to the immunity in patients with pulmonary tuberculosis]. (10479931)
1999
44
In vivo platelet and T-lymphocyte activities during pulmonary tuberculosis. (9877494)
1998
45
Cytokine gene expression profile of circulating CD4+ T cells in active pulmonary tuberculosis. (9118695)
1997
46
Increased production of hydrogen peroxide and expression of CD11b/CD18 on alveolar macrophages in patients with active pulmonary tuberculosis. (8959153)
1996
47
Pulmonary tuberculosis with anthracosis: an unusual diagnosis by fine needle aspiration cytology. (8328256)
1993
48
Rapidly progressive glomerulonephritis and pulmonary tuberculosis. (2020362)
1991
49
Nocardiosis mimicking pulmonary tuberculosis in Ugandan AIDS patients. (1889302)
1991
50
Pulmonary hypertrophic osteoarthropathy (periostitis); its absence in pulmonary tuberculosis. (13552924)
1958

Variations for Pulmonary Tuberculosis

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Expression for genes affiliated with Pulmonary Tuberculosis

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LifeMap Discovery
Genes differentially expressed in tissues of Pulmonary Tuberculosis patients vs. healthy controls: 30 (show all 99)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1ALBalbuminKidney-5.370.000
2CTXN3cortexin 3Kidney-5.370.000
3C2orf40chromosome 2 open reading frame 40Kidney-5.350.000
4HAO2hydroxyacid oxidase 2 (long chain)Kidney-5.320.001
5NOS1nitric oxide synthase 1 (neuronal)Kidney-5.310.000
6EYA4eyes absent homolog 4 (Drosophila)Kidney-5.290.001
7PCK1phosphoenolpyruvate carboxykinase 1 (soluble)Kidney-5.290.000
8FABP4fatty acid binding protein 4, adipocyteKidney-5.280.000
9MECOMMDS1 and EVI1 complex locusKidney-5.270.000
10TMEM178Atransmembrane protein 178AKidney-5.260.001
11RENreninKidney-5.260.000
12ZNF44zinc finger protein 44Kidney-5.250.000
13CRYAAcrystallin, alpha AKidney-5.240.000
14SERPINA5serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5Kidney-5.240.000
15ADH1Balcohol dehydrogenase 1B (class I), beta polypeptideKidney-5.220.000
16FGF9fibroblast growth factor 9Kidney-5.190.000
17RAB25RAB25, member RAS oncogene familyKidney-5.180.000
18UPP2uridine phosphorylase 2Kidney-5.180.001
19AQP2aquaporin 2 (collecting duct)Kidney-5.150.000
20TPCN2two pore segment channel 2Kidney-5.140.000
21NTRK2neurotrophic tyrosine kinase, receptor, type 2Kidney-5.120.001
22ATP6V1B1ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1Kidney-5.110.000
23AFMafaminKidney-5.110.000
24TBX2T-box 2Kidney-5.090.000
25STAP1signal transducing adaptor family member 1Kidney-5.070.000
26RALGAPA2Ral GTPase activating protein, alpha subunit 2 (catalytic)Kidney-5.050.000
27MMEmembrane metallo-endopeptidaseKidney-5.040.002
28AGXTalanine-glyoxylate aminotransferaseKidney-5.040.000
29ERBB4v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4Kidney-5.040.003
30SLC22A7solute carrier family 22 (organic anion transporter), member 7Kidney-5.040.001
31MT1Gmetallothionein 1GKidney-5.020.000
32TCEAL2transcription elongation factor A (SII)-like 2Kidney-4.990.000
33CYP4F2cytochrome P450, family 4, subfamily F, polypeptide 2Kidney-4.990.000
34XPNPEP2X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-boundKidney-4.990.000
35WT1Wilms tumor 1Kidney-4.990.000
36C7complement component 7Kidney-4.960.000
37LOC285556uncharacterized LOC285556Kidney-4.940.000
38TMEM45Btransmembrane protein 45BKidney-4.930.001
39ATP6V1C2ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2Kidney-4.920.000
40BHMTbetaine--homocysteine S-methyltransferaseKidney-4.920.001
41DUSP9dual specificity phosphatase 9Kidney-4.920.000
42TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)Kidney-4.910.000
43VAT1Lvesicle amine transport 1-likeKidney-4.910.000
44EMCNendomucinKidney-4.900.000
45TSPAN8tetraspanin 8Kidney-4.900.006
46SIM2single-minded family bHLH transcription factor 2Kidney-4.900.000
47PLGplasminogenKidney-4.890.000
48DMRT2doublesex and mab-3 related transcription factor 2Kidney-4.890.000
49KHKketohexokinase (fructokinase)Kidney-4.890.000
50HRGhistidine-rich glycoproteinKidney-4.880.000
51ACPPacid phosphatase, prostateKidney-4.860.000
52TMEM72transmembrane protein 72Kidney-4.850.000
53DACH1dachshund family transcription factor 1Kidney-4.850.001
54PTGDSprostaglandin D2 synthase 21kDa (brain)Kidney-4.830.001
55IRX1iroquois homeobox 1Kidney-4.810.000
56FOLH1folate hydrolase (prostate-specific membrane antigen) 1Kidney-4.810.000
57ATP6V0D2ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2Kidney-4.800.000
58LOC149703uncharacterized LOC149703Kidney-4.800.001
59GATA3GATA binding protein 3Kidney-4.780.000
60FGF1fibroblast growth factor 1 (acidic)Kidney-4.760.000
61ELF5E74-like factor 5 (ets domain transcription factor)Kidney-4.760.000
62KCNE1potassium voltage-gated channel, Isk-related family, member 1Kidney-4.750.000
63SEMA3Gsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3GKidney-4.740.000
64CASRcalcium-sensing receptorKidney-4.740.001
65ANGPTL3angiopoietin-like 3Kidney-4.720.000
66SLC34A1solute carrier family 34 (type II sodium/phosphate contransporter), member 1Kidney-4.710.000
67PAHphenylalanine hydroxylaseKidney-4.710.000
68ERICH4glutamate-rich 4Kidney-4.700.000
69CLCNKBchloride channel, voltage-sensitive KbKidney-4.700.000
70TFAP2Btranscription factor AP-2 beta (activating enhancer binding protein 2 beta)Kidney-4.690.001
71SLC13A2solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2Kidney-4.680.001
72CA4carbonic anhydrase IVKidney-4.670.000
73FCN3ficolin (collagen/fibrinogen domain containing) 3Kidney-4.670.000
74GBP6guanylate binding protein family, member 6Blood+4.380.000
75ANKRD22ankyrin repeat domain 22Blood+4.040.000
76PDCD1LG2programmed cell death 1 ligand 2Blood+4.030.000
77CD274CD274 moleculeBlood+3.870.000
78LINC00668long intergenic non-protein coding RNA 668Blood+3.600.000
79C1QCcomplement component 1, q subcomponent, C chainBlood+3.560.000
80CR1complement component (3b/4b) receptor 1 (Knops blood group)Blood+3.540.000
81KREMEN1kringle containing transmembrane protein 1Blood+3.490.000
82CACNA1Ecalcium channel, voltage-dependent, R type, alpha 1E subunitBlood+3.460.000
83BATF2basic leucine zipper transcription factor, ATF-like 2Blood+3.420.000
84BPIFB1BPI fold containing family B, member 1Lung+3.390.013
85BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 1Blood+3.380.000
86S100A12S100 calcium binding protein A12Lung-3.380.026
87NAIPNLR family, apoptosis inhibitory proteinBlood+3.340.000
88DICER1dicer 1, ribonuclease type IIIBlood+3.260.000
89SERPIND1serpin peptidase inhibitor, clade D (heparin cofactor), member 1Lung+3.230.020
90FGF13fibroblast growth factor 13Blood+3.200.000
91KRT17keratin 17Lung+3.200.000
92HLA-DOAmajor histocompatibility complex, class II, DO alphaLung+3.200.002
93APOL6apolipoprotein L, 6Blood+3.160.000
94DEFA1defensin, alpha 1Lung-3.150.000
95C1QBcomplement component 1, q subcomponent, B chainBlood+3.150.000
96SPP1secreted phosphoprotein 1Lung+3.150.000
97CARD17caspase recruitment domain family, member 17Blood+3.140.000
98LINC00342long intergenic non-protein coding RNA 342Blood+3.100.000
99MMP7matrix metallopeptidase 7 (matrilysin, uterine)Lung+3.010.000

Search GEO for disease gene expression data for Pulmonary Tuberculosis.

Pathways for genes affiliated with Pulmonary Tuberculosis

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Pathways related to Pulmonary Tuberculosis according to GeneCards Suite gene sharing:

(show all 19)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.9IFNG, IFNGR1
29.9IFNGR1, IFNG
39.7IFNG, IL12B
49.7IL12B, IFNG
59.7IL12B, IFNG
69.7IFNG, IL12B
79.7IL12B, IFNG
8
Show member pathways
Immune response CD16 signaling in NK cells58
9.6KIR2DS3, IFNG, IFNGR1
9
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
9.5IFNG, IFNGR1, TLR1
10
Show member pathways
9.5IFNG, IFNGR1, TLR1
119.5TLR1, IFNGR1, IFNG
12
Show member pathways
Type III interferon signaling36
9.5IL12B, IFNG, IFNGR1
13
Show member pathways
9.5IL12B, IFNG, IFNGR1
14
Show member pathways
9.3TLR1, IFNG, IL12B
15
Show member pathways
9.2IRGM, IFNGR1, IFNG, IL12B
16
Show member pathways
9.2IFNGR1, IFNG, IL12B, KIR2DS3
17
Show member pathways
IL27-mediated signaling events36
9.1IL12B, IFNG, IFNGR1, TLR1
18
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
9.1IL12B, IFNG, IFNGR1, TLR1
199.1IL12B, IFNG, IFNGR1, TLR1

Compounds for genes affiliated with Pulmonary Tuberculosis

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Compounds related to Pulmonary Tuberculosis according to GeneCards Suite gene sharing:

(show all 23)
idCompoundScoreTop Affiliating Genes
1cellulose acetate4310.2ADA, HP
2deferoxamine43 1211.2HP, IFNGR1
3con a4310.1HP, IFNG
4sodium stibogluconate43 1211.1IFNG, ADA
5amphotericin b4310.1IFNG, ADA
6sulfasalazine28 43 49 1213.1IL12B, HP
7niacin43 1211.1ADA, HP
8il-124310.0IL12B, IFNG
92,5-oligoadenylate4310.0ADA, IFNG
10lipoteichoic acid439.9TLR1, IL12B
11tuberculin439.9HP, IFNG, ADA
12ribavirin43 49 1211.9ADA, IFNG, HP
13neopterin439.9ADA, IFNG, HP
14polyinosinic-polycytidylic acid439.8IFNG, IL12B
15pentoxifylline43 1210.8HP, IL12B, IFNG
16endotoxin439.8IFNG, IL12B, HP
17il 10439.7IL12B, IFNG
18rolipram43 59 2811.7IFNG, ADA
19imiquimod43 59 28 1212.7IL12B, IFNG, TLR1
20vitamin d439.6IL12B, HP, SLC11A1
21poly(i-c)439.4IL12B, IFNG
22cyclosporin a43 28 5911.3HP, IFNG, ADA, HLA-S
23nitric oxide43 24 1211.3SLC11A1, HP, IL12B, IFNG

GO Terms for genes affiliated with Pulmonary Tuberculosis

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Cellular components related to Pulmonary Tuberculosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phagocytic vesicle membraneGO:00306709.5SLC11A1, IRGM, TLR1
2integral component of plasma membraneGO:00058878.8SLC11A1, KIR3DS1, KIR2DS3, IFNGR1, TLR1
3extracellular spaceGO:00056158.3SFTPA2, ADA, IFNG, IL12B, HP

Biological processes related to Pulmonary Tuberculosis according to GeneCards Suite gene sharing:

(show all 21)
idNameGO IDScoreTop Affiliating Genes
1macrophage activationGO:004211610.2SLC11A1, TLR1
2regulation of interferon-gamma-mediated signaling pathwayGO:006033410.1IFNG, IFNGR1
3positive regulation of T-helper 1 type immune responseGO:000282710.1IL12B, SLC11A1
4protein import into nucleus, translocationGO:000006010.1SLC11A1, IFNG
5positive regulation of interleukin-6 biosynthetic processGO:004541010.1TLR1, IFNG
6positive regulation of smooth muscle cell apoptotic processGO:003439310.1IFNG, IL12B
7negative regulation of interleukin-17 productionGO:003270010.0IL12B, IFNG
8defense response to Gram-negative bacteriumGO:005082910.0SLC11A1, IL12B
9negative regulation of growth of symbiont in hostGO:004413010.0IFNG, IL12B
10positive regulation of osteoclast differentiationGO:004567210.0IFNG, IL12B
11defense response to bacteriumGO:00427429.9SLC11A1, HP, IFNG
12positive regulation of interleukin-12 productionGO:00327359.9IFNG, IL12B
13negative regulation of smooth muscle cell proliferationGO:00486629.9IL12B, IFNG
14natural killer cell activationGO:00301019.9KIR3DS1, IL12B
15positive regulation of cell adhesionGO:00457859.8IFNG, IL12B
16positive regulation of interferon-gamma productionGO:00327299.8SLC11A1, IL12B
17defense response to protozoanGO:00428329.8SLC11A1, IL12B, IFNG
18response to hydrogen peroxideGO:00425429.8ADA, HP
19positive regulation of tumor necrosis factor productionGO:00327609.8IFNG, IL12B
20inflammatory responseGO:00069549.6SLC11A1, IRGM, TLR1
21positive regulation of T cell proliferationGO:00421029.4IL12B, IFNG

Products for genes affiliated with Pulmonary Tuberculosis

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  • Antibodies
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Sources for Pulmonary Tuberculosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet