MCID: PLM040
MIFTS: 20

Pulmonary Valve Disease malady

Cardiovascular category

Summaries for Pulmonary Valve Disease

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33MalaCards
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MalaCards: Pulmonary Valve Disease, also known as pulmonary valve disorder, is related to rheumatic pulmonary valve disease and rheumatic disease. An important gene associated with Pulmonary Valve Disease is GATA6 (GATA binding protein 6), and among its related pathways are Platelet activation, signaling and aggregation and G-AlphaQ Signaling. Related mouse phenotype muscle.

Aliases & Classifications for Pulmonary Valve Disease

Sources:
8Disease Ontology, 61UMLS, 27ICD9CM, 40NCIt, 57SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular


Aliases & Descriptions:

pulmonary valve disease 8
pulmonary valve disorder 8 61


External Ids:

Disease Ontology8 DOID:5749
ICD9CM27 424.3
SNOMED-CT57 76267008, 195001000
NCIt40 C78579
ICD1025 I37, I39.3

Related Diseases for Pulmonary Valve Disease

Sources:
17GeneCards, 18GeneDecks
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Diseases in the pulmonary valve insufficiency family:

pulmonary valve disease

Diseases related to Pulmonary Valve Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1rheumatic pulmonary valve disease10.4
2rheumatic disease10.2
3pulmonary valve insufficiency10.1
4aortic disease10.1
5devic disease10.1
6aortic valve disease10.1

Graphical network of diseases related to Pulmonary Valve Disease:



Diseases related to pulmonary valve disease

Clinical Features for Pulmonary Valve Disease

Drugs & Therapeutics for Pulmonary Valve Disease

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Pulmonary Valve Disease

Drug clinical trials:

Search ClinicalTrials for Pulmonary Valve Disease

Search NIH Clinical Center for Pulmonary Valve Disease

Search CenterWatch for Pulmonary Valve Disease

Genetic Tests for Pulmonary Valve Disease

Anatomical Context for Pulmonary Valve Disease

Animal Models for Pulmonary Valve Disease or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Pulmonary Valve Disease:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.1GATA6, SOS1

Publications for Pulmonary Valve Disease

Sources:
51PubMed
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Articles related to Pulmonary Valve Disease:

(show all 44)
idTitleAuthorsYear
1
Importance of pulmonary valve disease during implantation of a biventricular assist device. (24268185)
2013
2
A new transventricular aproach for pulmonary valve implantation in a patient with severe valve disease after tetralogy-of-Fallot repair. (23735937)
2013
3
Compounded pimobendan for canine chronic degenerative mitral valve disease and pulmonary hypertension. (23050309)
2012
4
Prognostic value of pulmonary hypertension in patients undergoing surgery for degenerative mitral valve disease with leaflet prolapse. (23173853)
2012
5
Pulmonary hypertension in canine degenerative mitral valve disease. (22364721)
2012
6
Mid-term results of the box pulmonary vein isolation and the cryo-maze procedure for chronic atrial fibrillation associated with mitral valve disease. (22327852)
2012
7
Pulmonary valve replacement in chronic pulmonary regurgitation in adults with congenital heart disease: impact of preoperative QRS-duration and NT-proBNP levels on postoperative right ventricular function. (20598759)
2011
8
Solitary pulmonary mass in mitral valve disease. (21739663)
2011
9
Supracardiac total anomalous pulmonary venous connection with severe rheumatic mitral valve disease. (21951039)
2011
10
Late clinical manifestations of mitral valve disease and severe pulmonary hypertension in a patient diagnosed with premature closure of foramen ovale during fetal life. (21574036)
2011
11
Tricuspid and pulmonary valve disease evaluation and management. (21070730)
2010
12
Anomalous origin of right coronary artery from pulmonary artery and severe mitral regurgitation due to myxomatous mitral valve disease: a case report and literature review. (20351394)
2010
13
Evaluation of pimobendan and N-terminal probrain natriuretic peptide in the treatment of pulmonary hypertension secondary to degenerative mitral valve disease in dogs. (19780931)
2009
14
Randomized study of surgical isolation of the pulmonary veins for correction of permanent atrial fibrillation associated with mitral valve disease. (19619795)
2009
15
Increased concentrations of serotonin and 5-hydroxyindoleacetic acid in blood plasma from patients with pulmonary hypertension due to mitral valve disease. (19704935)
2009
16
Pulmonary valve replacement: extending the indications to the whole spectrum of pulmonary valve disease. (19804205)
2007
17
Surgery for paroxysmal atrial fibrillation in the setting of mitral valve disease: a role for pulmonary vein isolation? (16368329)
2006
18
Doppler echocardiography-derived evidence of pulmonary arterial hypertension in dogs with degenerative mitral valve disease: 86 cases (2001-2005). (17144824)
2006
19
Disclosure of a financial relationship relating to "surgery for paroxysmal atrial fibrillation in the setting of mitral valve disease: a role for pulmonary vein isolation. Ann Thorac Surg 2006;81:19-28". (16488760)
2006
20
Percutaneous stent-mounted valve for treatment of aortic or pulmonary valve disease. (15343576)
2004
21
Isolation of the pulmonary veins in patients with permanent atrial fibrillation secondary to mitral valve disease. (15320554)
2004
22
Encircling isolation of pulmonary vein orifice for elimination of persistent atrial fibrillation associated with mitral valve disease. (12974929)
2003
23
Ablation of atrial fibrillation in mitral valve disease patients: five year follow-up after percutaneous pulmonary vein isolation and mitral balloon valvuloplasty. (14655306)
2003
24
Pulmonary vein isolation and left atrial reduction for chronic atrial fibrillation secondary to mitral valve disease. (12735613)
2003
25
Carcinoid syndrome: an unusual cause of tricuspid and pulmonary valve disease. (12876616)
2003
26
Pulmonary vein isolation for chronic atrial fibrillation associated with mitral valve disease: the midterm results. (12027794)
2002
27
Simple surgical isolation of pulmonary veins for treating secondary atrial fibrillation in mitral valve disease. (11996258)
2002
28
Pulmonary parenchymal manifestations of mitral valve disease. (10464803)
1999
29
Possibility of focal activation around the left upper pulmonary vein during chronic atrial fibrillation with mitral valve disease. (10332117)
1999
30
Rheumatic pulmonary valve disease. (11273310)
1998
31
Mitral valve prolapse in a case of Marfan syndrome with congenital cardiac disease, chronic obstructive pulmonary disease and schizophrenia. (7567172)
1995
32
Pulmonary autograft for aortic valve replacement in rheumatic disease: a caveat. (7646153)
1995
33
Pulmonary autograft for aortic valve replacement in rheumatic disease--an ideal solution? (7952312)
1994
34
Echocardiographic evaluation of isolated pulmonary valve disease in adolescents and adults. (10146329)
1993
35
Use of prostaglandin E1 to treat peri-anaesthetic pulmonary hypertension associated with mitral valve disease. (8299860)
1993
36
Surgical correction of congenital left coronary-pulmonary artery fistula and rheumatic mitral valve disease. Case report. (2749212)
1989
37
Pulmonary varix associated with mitral valve disease. (3319185)
1987
38
Pulmonary precapillary hypertension in mitral valve disease. (6851571)
1983
39
Intravenous verapamil to relieve pulmonary congestion in patients with mitral valve disease. (6837978)
1983
40
Pulmonary varices associated with mitral valve disease: a case report and survey of the literature. (7138113)
1982
41
Pulmonary edema after ritodrine infusion for premature labor in a patient with mitral valve disease. (7211242)
1981
42
The relationship of pulmonary artery wedge pressure to the posterior aortic wall echocardiogram in patients free of obstructive mitral valve disease. (7415938)
1980
43
'Isolated' pulmonary valve stenosis as part of more widespread cardiovascular disease. (944584)
1976
44
Rheumatic pulmonary valve disease. (5380838)
1969

Genetic Variations for Pulmonary Valve Disease

Expression for genes affiliated with Pulmonary Valve Disease

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pulmonary Valve Disease

Search GEO for disease gene expression data for Pulmonary Valve Disease.

Pathways for genes affiliated with Pulmonary Valve Disease

Sources:
54Reactome, 52QIAGEN
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Pathways related to Pulmonary Valve Disease according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.1GATA6, SOS1
2
Hide members
9.1GATA6, SOS1

Compounds for genes affiliated with Pulmonary Valve Disease

GO Terms for genes affiliated with Pulmonary Valve Disease

Sources:
16Gene Ontology
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Biological processes related to Pulmonary Valve Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood coagulationGO:0075969.1GATA6, SOS1

Products for genes affiliated with Pulmonary Valve Disease

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  • Lysates
  • Antibodies

Sources for Pulmonary Valve Disease

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet