MCID: PLM068
MIFTS: 40

Pulmonary Vein Stenosis malady

Categories: Rare diseases, Cardiovascular diseases

Aliases & Classifications for Pulmonary Vein Stenosis

Aliases & Descriptions for Pulmonary Vein Stenosis:

Name: Pulmonary Vein Stenosis 50 69
Pulmonary Veins Stenosis 50

Classifications:



Summaries for Pulmonary Vein Stenosis

NIH Rare Diseases : 50 pulmonary vein stenosis is a very rare and serious condition in which there is a blockage in the blood vessels that bring oxygen-rich blood from the lungs back to the heart. this condition can be isolated to one vein, but often affects multiple veins. stenosis occurs when there is an abnormal thickening and narrowing of the walls of the veins. pulmonary vein stenosis is a progressive condition and may lead to total obstruction to a blood vessel. most commonly, all of the pulmonary veins of one lung are affected, causing pulmonary hypertension and pulmonary arterial hypertension. surgery and catheterization to widen the narrow veins is usually a short-term solution since the obstruction typically recurs. last updated: 9/1/2011

MalaCards based summary : Pulmonary Vein Stenosis, also known as pulmonary veins stenosis, is related to atrial fibrillation and invasive mole. An important gene associated with Pulmonary Vein Stenosis is PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1), and among its related pathways/superpathways are Actin Nucleation by ARP-WASP Complex and p70S6K Signaling. The drugs Adenosine and Tadalafil have been mentioned in the context of this disorder. Affiliated tissues include lung and heart, and related phenotypes are cardiovascular system and cellular

Wikipedia : 71 Pulmonary vein stenosis is a rare cardiovascular disorder. It is recognized as being the stenosis of one... more...

Related Diseases for Pulmonary Vein Stenosis

Diseases related to Pulmonary Vein Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
id Related Disease Score Top Affiliating Genes
1 atrial fibrillation 10.5
2 invasive mole 10.3 KIT PDGFRA
3 mucinous cystadenocarcinoma 10.3 ACTC1 MKI67
4 ganglioneuroma 10.3 KIT PDGFRA
5 dfnb1 10.2 KIT PDGFRA
6 uremic neuropathy 10.2 KIT PDGFRA
7 kahrizi syndrome 10.2 KIT PDGFRA
8 amaurosis congenita, cone-rod type, with congenital hypertrichosis 10.2 KIT PDGFRA
9 malignant epithelial mesothelioma 10.2 KIT PDGFRA
10 hemiplegic migraine 10.2 KDR PECAM1
11 olfactory nerve disease 10.2 KIT PDGFRA
12 larynx leiomyosarcoma 10.2 KIT PDGFRA
13 keratosis follicularis spinulosa decalvans 10.2 KDR PECAM1
14 rectum leiomyoma 10.2 KIT PDGFRA
15 uterine hypoplasia 10.2 KIT MKI67
16 cerebral arterial disease 10.2 KIT PDGFRA
17 fragile x-associated tremor/ataxia syndrome 10.2 KIT PDGFRA
18 kidney clear cell sarcoma 10.2 KIT PDGFRA
19 vesiculobullous skin disease 10.2 KDR PECAM1
20 oral erosive lichen 10.2 ACTC1 DES
21 vagina leiomyosarcoma 10.2 ACTC1 DES
22 neuropathy with hearing impairment 10.2 KDR PECAM1
23 osteomyelitis 10.2 ACTC1 DES
24 myoma 10.2 ACTC1 DES
25 foix-alajouanine syndrome 10.2 DES MKI67
26 congenital myasthenic syndrome 10.2 ACTC1 DES
27 benign idiopathic neonatal seizures 10.2 KDR PECAM1
28 spleen angiosarcoma 10.2 ACTC1 DES
29 malignant dermis tumor 10.2 ACTC1 DES
30 tibial aplasia ectrodactyly hydrocephalus 10.2 CD99 KIT
31 urethral cancer 10.2 ACTC1 DES
32 hyperandrogenism due to cortisone reductase deficiency 10.2 KIT PDGFRA
33 biemond syndrome 10.2 ACTC1 DES
34 testis sarcoma 10.2 DES KIT
35 marfanoid hypermobility syndrome 10.2 DES KIT
36 intestinal obstruction 10.2 ACTC1 DES
37 alcohol-induced mental disorder 10.2 KDR KIT
38 tricuspid valve prolapse 10.2 KDR PDGFRA
39 male urethral cancer 10.2 ACTC1 DES
40 episodic ataxia 10.2 ACTC1 DES
41 liver angiosarcoma 10.2 DES KIT
42 mediastinum liposarcoma 10.2 ACTC1 DES
43 fibrosarcoma 10.2 KIT PDGFRA
44 coronary stenosis 10.2 ACTC1 DES
45 dyslexia 10.1 ACTC1 DES
46 small intestinal sarcoma 10.1 KIT PDGFRA
47 house allergic alveolitis 10.1 ACTC1 DES
48 glycerol kinase deficiency, adult form 10.1 ACTC1 KIT PECAM1
49 glomangioma 10.1 ACTC1 DES
50 subependymal glioma 10.1 KDR MKI67 PDGFRA

Graphical network of the top 20 diseases related to Pulmonary Vein Stenosis:



Diseases related to Pulmonary Vein Stenosis

Symptoms & Phenotypes for Pulmonary Vein Stenosis

MGI Mouse Phenotypes related to Pulmonary Vein Stenosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.87 ACTC1 DES F2RL1 KDR KIT PDGFRA
2 cellular MP:0005384 9.86 ACTC1 DES F2RL1 KDR KIT PDGFRA
3 homeostasis/metabolism MP:0005376 9.76 ACTC1 DES F2RL1 KDR KIT PDGFRA
4 muscle MP:0005369 9.43 ACTC1 DES KDR KIT PDGFRA PECAM1
5 skeleton MP:0005390 9.1 F2RL1 KDR KIT PDGFRA PECAM1 TYMP

Drugs & Therapeutics for Pulmonary Vein Stenosis

Drugs for Pulmonary Vein Stenosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 92)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Adenosine Approved, Investigational Phase 4,Phase 2 58-61-7 60961
2
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
3
Amiodarone Approved, Investigational Phase 4 1951-25-3 2157
4
Propafenone Approved Phase 4 54063-53-5 4932
5
Sotalol Approved Phase 4 959-24-0, 3930-20-9 5253
6
Dobutamine Approved Phase 4 34368-04-2 36811
7 Analgesics Phase 4,Phase 2
8 Peripheral Nervous System Agents Phase 4,Phase 2
9 Adrenergic Agents Phase 4,Phase 2
10 Adrenergic Agonists Phase 4,Phase 2
11 Adrenergic beta-Agonists Phase 4,Phase 2
12 Neurotransmitter Agents Phase 4,Phase 2
13 Vasodilator Agents Phase 4,Phase 2
14 Anti-Arrhythmia Agents Phase 4,Phase 3,Phase 2,Phase 1
15 Protective Agents Phase 4,Phase 2
16 Autonomic Agents Phase 4,Phase 2
17 Phosphodiesterase 5 Inhibitors Phase 4
18 Phosphodiesterase Inhibitors Phase 4
19 Sodium Channel Blockers Phase 4
20 Diuretics, Potassium Sparing Phase 4
21 Simendan Phase 4
22
Apixaban Approved Phase 3 503612-47-3 10182969
23
protease inhibitors Phase 3
24 Serine Proteinase Inhibitors Phase 3
25 HIV Protease Inhibitors Phase 3
26 Factor Xa Inhibitors Phase 3
27 Anticoagulants Phase 3
28 Antithrombin III Phase 3
29 Antithrombins Phase 3
30 serine Nutraceutical Phase 3
31
Isoproterenol Approved Phase 2 7683-59-2 3779
32
Vinblastine Approved Phase 2 865-21-4 13342 241903
33
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
34
Losartan Approved Phase 1, Phase 2 114798-26-4 3961
35
Bevacizumab Approved, Investigational Phase 1, Phase 2 216974-75-3
36
leucovorin Approved, Nutraceutical Phase 2 58-05-9 54575, 6560146 143
37
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
38
Pirfenidone Investigational Phase 2 53179-13-8 40632
39 Analgesics, Non-Narcotic Phase 2
40 Anti-Inflammatory Agents Phase 2
41 Anti-Inflammatory Agents, Non-Steroidal Phase 2
42 Antirheumatic Agents Phase 2
43 Folic Acid Antagonists Phase 2
44 Nucleic Acid Synthesis Inhibitors Phase 2
45 Dermatologic Agents Phase 2
46 Vitamin B Complex Phase 2
47 Anti-Asthmatic Agents Phase 2
48 Immunosuppressive Agents Phase 2
49 Antimetabolites Phase 2
50 Respiratory System Agents Phase 2

Interventional clinical trials:

(show top 50) (show all 57)
id Name Status NCT ID Phase
1 Cardioversion vs. Catheter Ablation for Persistent Atrial Fibrillation Unknown status NCT00196209 Phase 4
2 A Prospective Randomized Study Comparing Radiofrequency Energy With Cryoenergy Unknown status NCT00773539 Phase 4
3 PV-Isolation With the Cryoballoon Versus RF:a Randomized Controlled Prospective Non-inferiority Trial (FreezeAF) Completed NCT00774566 Phase 4
4 Randomized Trial of Two Ablation Catheters in Paroxysmal Atrial Fibrillation Completed NCT00678340 Phase 4
5 ADenosine Following Pulmonary Vein Isolation to Target Dormant Conduction Elimination: the ADVICE Trial Completed NCT01058980 Phase 4
6 Additional Linear Ablation Beyond Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation Recruiting NCT02637453 Phase 4
7 Aortic Stenosis and PhosphodiEsterase Type 5 iNhibition (ASPEN): A Pilot Study Recruiting NCT01275339 Phase 4
8 Kansai Plus Atrial Fibrillation Trial Active, not recruiting NCT01477983 Phase 4
9 The Effects of Dobutamine on Postoperative Cardiac Function in Aortic Valve Replacement Suspended NCT01375335 Phase 4
10 Mesh Ablator Versus Cryoballoon Pulmonary Vein Ablation of Symptomatic Paroxysmal Atrial Fibrillation Terminated NCT01061931 Phase 4
11 Efficacy, Safety and Efficiency Study of CARTO® 3 System Guided THERMOCOOL® Catheter Ablation Versus Fluoroscopy Guided Ablation With the Pulmonary Vein Ablation Catheter® (PVAC®) Terminated NCT01116557 Phase 4
12 Aortic Stenosis and PhosphodiEsterase iNhibition With Aortic Valve Replacement (ASPEN-AVR): A Pilot Study Terminated NCT01272388 Phase 4
13 Effects of Levosimendan in Patients Eligible for Aortic Valve Replacement With Left Ventricular Hypertrophy Terminated NCT01188369 Phase 4
14 SOLAR & ATRILAZE Atrial Fibrillation Trial Unknown status NCT00734058 Phase 3
15 Prevention of Autogenous Vein Graft Failure in Coronary Artery Bypass Procedures Completed NCT00042081 Phase 3
16 Anti-Thrombotic Strategy After Trans-Aortic Valve Implantation for Aortic Stenosis Recruiting NCT02664649 Phase 3
17 Study of HD Mesh Ablation System for Treatment of Paroxysmal Atrial Fibrillation Terminated NCT00741611 Phase 3
18 Vinblastine and Methotrexate in Children With Pulmonary Vein Stenosis Completed NCT00215046 Phase 2
19 Treatment of Atrial Fibrillation by Minimal Invasive Surgery Completed NCT00448656 Phase 2
20 Adenosine to Assess Complete Conduction Block During Catheter Ablation of Paroxysmal Atrial Fibrillation Completed NCT03032965 Phase 2
21 Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery Completed NCT00903370 Phase 2
22 REVOLUTION (WFCC-133) - Treatment of Paroxysmal Atrial Fibrillation Completed NCT01353586 Phase 2
23 Pirfenidone to Treat Hypertrophic Cardiomyopathy Completed NCT00011076 Phase 2
24 Pilot Trial: the Safety and Feasibility of Losartan for Pulmonary Vein Stenosis Recruiting NCT02769130 Phase 1, Phase 2
25 Pilot Study Using Avastin and Gleevec to Treat the Progression of Intraluminal Pulmonary Vein Stenosis Active, not recruiting NCT00891527 Phase 1, Phase 2
26 RF Ablation of Atrial Fibrillation Completed NCT00265629 Phase 1
27 T Cell Effector and Regulatory Mechanisms in Asthma Completed NCT01612936 Phase 1
28 MRI to Detect Embolism Following Angiography and Angioplasty-Stenting of the Renal Artery Completed NCT00027469 Phase 1
29 Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic Access Enrolling by invitation NCT02280824 Phase 1
30 Failed Retrieval of Inferior Vena Cava (IVC) Filters: Long-Term Outcomes Unknown status NCT00163956
31 Antiplatelet Therapy Continuation in Spine Surgery - Its Effect on Postoperative Morbidity and Mortality Unknown status NCT01006083
32 Safety Monitoring of Patients Having Pulmonary Vein Ablation Completed NCT00590668
33 A Study of Strategies for Electrical Isolation of Pulmonic Veins for Curative Treatment of Atrial Fibrillation Completed NCT00434694
34 STAR-AF:Substrate Versus Trigger Ablation for Reduction of Atrial Fibrillation Trial Completed NCT00367757
35 Radiofrequency Ablation of Drivers of Atrial Fibrillation Completed NCT00674401
36 Substrate and Trigger Ablation for Reduction of Atrial Fibrillation Trial - Star AF II Study Completed NCT01203748
37 Therapeutic Outcomes Using Contact Force Handling During Atrial Fibrillation Ablation Completed NCT01851525
38 Evaluation of Graft Material in Coronary Artery Bypass Grafting (CABG) Completed NCT01310725
39 The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery Completed NCT00348920
40 The Role of Heart Stiff and Weak Atrium on Exercise Capacity in Patients With Hypertrophic Cardiomyopathy Completed NCT00074880
41 Effectiveness Study of Circumferential vs. Segmental Ablation in Paroxysmal Atrial Fibrillation Recruiting NCT02106663
42 Non-invasive Characterization of the Mechanisms of Atrial Fibrillation Maintenance Recruiting NCT02497248
43 Cryoballoon Atrial Fibrillation Ablation Registry Recruiting NCT03040037
44 Efficacy of Delayed Enhancement MRI-Guided Ablation vs Conventional Catheter Ablation of Atrial Fibrillation Recruiting NCT02529319
45 Ablation and Left Atrium Reduction During Mitral Valve Surgery for Atrial Fibrillation Recruiting NCT02047279
46 Use of a High Density Mapping System to Complete Wide Area Circumferential Ablation of the Pulmonary Veins and Avoid Ostial Segmental Ablation Recruiting NCT02917044
47 Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency Department Recruiting NCT02781207
48 National Congenital Heart Disease Audit Recruiting NCT02303535
49 Ffr-gUidance for compLete Non-cuLprit REVASCularization Recruiting NCT02862119
50 Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease Recruiting NCT02400229

Search NIH Clinical Center for Pulmonary Vein Stenosis

Genetic Tests for Pulmonary Vein Stenosis

Anatomical Context for Pulmonary Vein Stenosis

MalaCards organs/tissues related to Pulmonary Vein Stenosis:

39
Lung, Heart

Publications for Pulmonary Vein Stenosis

Articles related to Pulmonary Vein Stenosis:

(show top 50) (show all 236)
id Title Authors Year
1
Pulmonary Vein Varix with Pulmonary Vein Stenosis. ( 28007075 )
2017
2
Pulmonary vein stenosis-novel strategies for a challenging and resistant condition? ( 26896354 )
2016
3
Recurrent Pulmonary Vein Stenosis After Pulmonary Vein Isolation. ( 28041807 )
2016
4
Severe Pulmonary Vein Stenosis Resulting From Ablation for Atrial Fibrillation: Presentation, Management, and Clinical Outcomes. ( 27793993 )
2016
5
Pulmonary Vein Stenosis After Second-Generation Cryoballoon Ablation. ( 28032927 )
2016
6
TCT-809 Stenting for the treatment of pulmonary vein stenosis after atrial fibrillation radiofrequency catheter ablation: initial experience with peripheral stents plus drug-coated balloons and coronary drug-eluting stents. ( 27970199 )
2016
7
Pulmonary veins stenosis after catheter ablation of atrial fibrillation as the cause of haemoptysis: Three cases and a literature review. ( 27216646 )
2016
8
Pulmonary vein stenosis: Etiology, diagnosis and management. ( 26839659 )
2016
9
Pulmonary Vein Stenosis in Neonates with Severe Bronchopulmonary Dysplasia. ( 26862723 )
2016
10
Congenital pulmonary lymphangiectasia in patient with pulmonary vein stenosis/atresia. ( 27546704 )
2016
11
Pulmonary Vein Remodeling Following Atrial Fibrillation Ablation: Implications For The Radiographic Diagnosis Of Pulmonary Vein Stenosis. ( 27909538 )
2016
12
Hemoptysis and lung disease as a manifestation of pulmonary vein stenosis after cryoballoon catheter ablation for atrial fibrillation. ( 26811238 )
2016
13
Drug-Coated Balloon Venoplasty for In-Stent Restenosis in a Patient With Recurrent Pulmonary Vein Stenosis Post Ablation for Atrial Fibrillation: Initial Experience With a New Treatment Technique. ( 27145055 )
2016
14
Pulmonary vein collateral formation as a long-term result of post-interventional pulmonary vein stenosis. ( 26795444 )
2016
15
Pulmonary vein stenosis complicating radiofrequency catheter ablation for atrial fibrillation: A literature review. ( 27492534 )
2016
16
Pulmonary vein stenosis after atrial fibrillation ablation. ( 27174109 )
2016
17
Pulmonary vein stenosis: Plea for a multi-institutional registry. ( 26602902 )
2016
18
Surgical approaches to pulmonary vein stenosis in pediatric heart transplant recipients: Opportunity for success in a difficult situation. ( 27453521 )
2016
19
Congenital Pulmonary Vein Stenosis: Encouraging Mid-term Outcome. ( 26271471 )
2015
20
"How to do it": hybrid stent placement for pulmonary vein stenosis. ( 25870348 )
2015
21
Evaluation of Primary Pulmonary Vein Stenosis in Children: Comparison of Radionuclide Perfusion Lung Scan and Angiography. ( 26397339 )
2015
22
Pulmonary vein stenosis: Challenges ahead. ( 26277464 )
2015
23
Pulmonary Vein Stenosis After Minimally Invasive Stand-alone Surgical Ablation of Atrial Fibrillation. ( 25976163 )
2015
24
3-D Transoesophageal echocardiography for guiding percutaneous stenting of pulmonary vein stenosis. ( 25750199 )
2015
25
Successful stenting of left pulmonary veins stenosis resulting from fibrosing mediastinitis. ( 25586119 )
2015
26
Pulmonary vein stenosis after pulmonary vein isolation using duty-cycled unipolar/bipolar radiofrequency ablation guided by intracardiac echocardiography. ( 26081432 )
2015
27
The first reported case of pulmonary vein stenosis treated by percutaneous angioplasty with self-apposing drug-eluting stent implantation. ( 25464394 )
2015
28
Lung Infarction due to Pulmonary Vein Stenosis after Ablation Therapy for Atrial Fibrillation Misdiagnosed as Organizing Pneumonia: Sequential Changes on CT in Two Cases. ( 26175597 )
2015
29
Outcomes of surgery for young children with multivessel pulmonary vein stenosis. ( 26215353 )
2015
30
Pulmonary Hypertension in the Preterm Infant with Chronic Lung Disease can be Caused by Pulmonary Vein Stenosis: A Must-Know Entity. ( 26573816 )
2015
31
A Novel Hybrid Approach for Balloon Dilation of Pulmonary Vein Stenosis Following Total Anomalous Pulmonary Venous Connection Repair with Atrial Septal Patching. ( 25973524 )
2015
32
Down Syndrome with Complete Atrioventricular Septal Defect, Hypertrophic Cardiomyopathy, and Pulmonary Vein Stenosis. ( 26504441 )
2015
33
Severe Pulmonary Vein Stenosis and Extensive Left Atrial Stricture After Radiofrequency Catheter Ablation of Atrial Fibrillation. ( 25777614 )
2015
34
Pulmonary Vein Stenosis Mimicking Nonspecific Interstitial Pneumonia. ( 26779359 )
2015
35
Primary pulmonary vein stenosis: Can we expect different results? ( 26126465 )
2015
36
Catheter-based intervention for pulmonary vein stenosis due to fibrosing mediastinitis: The Mayo Clinic experience. ( 26925456 )
2015
37
Pulmonary Vein Stenosis in a Newborn: A Commonly Overlooked Diagnosis. ( 26457207 )
2015
38
Surgical repair for primary pulmonary vein stenosis: Single-institution, midterm follow-up. ( 25935589 )
2015
39
Pulmonary Vein Stenosis After Ablation: The Difference Between Clinical Symptoms and Imaging Findings, and the Importance of Definitions in This Context. ( 26546065 )
2015
40
Pulmonary Vein Stenosis Complicating Radiofrequency Catheter Ablation: Five Case Reports and Literature Review. ( 26313772 )
2015
41
Pulmonary vein stenosis after radiofrequency ablation: in vivo optical coherence tomography insights. ( 25525060 )
2015
42
Repair Type Influences Mode of Pulmonary Vein Stenosis in Total Anomalous Pulmonary Venous Drainage. ( 26138763 )
2015
43
Lung pathology in pediatric pulmonary vein stenosis. ( 26458037 )
2015
44
Multiple and aggressive pulmonary vein transcatheter interventions as bridge to transplantation in primary diffuse pulmonary vein stenosis. ( 26015092 )
2015
45
Pulmonary vein stenosis: Severity and location predict survival after surgical repair. ( 26481279 )
2015
46
Pulmonary Vein Stenosis After Cryoablation Using 28-mm Second-Generation Balloon. ( 25511425 )
2014
47
Pulmonary vein stenosis and necrotising enterocolitis: is there a possible link with necrotising enterocolitis? ( 24646617 )
2014
48
Losartan ameliorates "upstream" pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis. ( 25172325 )
2014
49
Primary pulmonary vein stenosis in a premature infant without bronchopulmonary dysplasia: a case report. ( 24992883 )
2014
50
Congenital pulmonary vein stenosis in an adult patient. ( 24184251 )
2014

Variations for Pulmonary Vein Stenosis

Expression for Pulmonary Vein Stenosis

Search GEO for disease gene expression data for Pulmonary Vein Stenosis.

Pathways for Pulmonary Vein Stenosis

GO Terms for Pulmonary Vein Stenosis

Cellular components related to Pulmonary Vein Stenosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.8 KIT PDGFRA PECAM1

Biological processes related to Pulmonary Vein Stenosis according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.7 KDR PDGFRA PECAM1
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.69 F2RL1 KDR PDGFRA
3 protein autophosphorylation GO:0046777 9.67 KDR KIT PDGFRA
4 peptidyl-tyrosine phosphorylation GO:0018108 9.65 KDR KIT PDGFRA
5 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.58 KDR KIT PDGFRA
6 muscle filament sliding GO:0030049 9.55 ACTC1 DES
7 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 9.54 KIT PDGFRA
8 positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 9.46 KIT PECAM1
9 embryonic hemopoiesis GO:0035162 9.43 KDR KIT
10 positive regulation of pseudopodium assembly GO:0031274 9.37 F2RL1 KIT
11 cardiac myofibril assembly GO:0055003 9.32 ACTC1 PDGFRA
12 positive regulation of positive chemotaxis GO:0050927 9.26 F2RL1 KDR
13 positive regulation of cell migration GO:0030335 9.26 F2RL1 KDR KIT PDGFRA
14 positive regulation of phospholipase C activity GO:0010863 9.16 KIT PDGFRA
15 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 8.92 F2RL1 KDR KIT PDGFRA

Molecular functions related to Pulmonary Vein Stenosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 9.43 KDR KIT PDGFRA
2 signal transducer, downstream of receptor, with protein tyrosine kinase activity GO:0004716 9.16 KDR KIT
3 vascular endothelial growth factor-activated receptor activity GO:0005021 8.96 KDR PDGFRA
4 transmembrane receptor protein tyrosine kinase activity GO:0004714 8.8 KDR KIT PDGFRA

Sources for Pulmonary Vein Stenosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....