Aliases & Classifications for Pulmonic Stenosis

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Aliases & Descriptions for Pulmonic Stenosis:

Name: Pulmonic Stenosis 45
Valvular Pulmonic Stenosis 45
 
Pulmonary Valve Stenosis 65
Pulmonary Stenosis 65

Classifications:



External Ids:

UMLS65 C1956257

Summaries for Pulmonic Stenosis

About this section
Wikipedia:68 Pulmonic stenosis, also known as pulmonary stenosis, is a dynamic or fixed obstruction of flow from the... more...

MalaCards based summary: Pulmonic Stenosis, also known as valvular pulmonic stenosis, is related to watson syndrome and leopard syndrome 1, and has symptoms including abnormality of the pulmonary artery, atria septal defect and pulmonic stenosis. An important gene associated with Pulmonic Stenosis is BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways are G-protein signaling M-RAS regulation pathway and Development_Leptin signaling via JAK/STAT and MAPK cascades. The drug alprostadil has been mentioned in the context of this disorder. Affiliated tissues include heart, breast and bone, and related mouse phenotypes are pigmentation and reproductive system.

Related Diseases for Pulmonic Stenosis

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Diseases related to Pulmonic Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 310)
idRelated DiseaseScoreTop Affiliating Genes
1watson syndrome33.4MAP2K2, NF1, PTPN11
2leopard syndrome 129.3BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
3retinal arterial macroaneurysm with supravalvular pulmonic stenosis12.8
4keutel syndrome11.7
5pulmonary subvalvular stenosis11.7
6leopard syndrome11.5
7pulmonary valve stenosis10.7
8cardiofaciocutaneous syndrome10.6
9heterotaxy, visceral, 1, x-linked10.6
10pilocytic astrocytoma10.5BRAF, NF1
11leopard syndrome 210.4
12leopard syndrome 310.4
13costello syndrome10.4
14cardiofaciocutaneous syndrome 210.4
15noonan syndrome 110.4
16cardiofaciocutaneous syndrome 310.4
17congenital heart defects, multiple types, 410.4
18left ventricular noncompaction 1, with or without congenital heart defects10.4
19cardiofaciocutaneous syndrome 410.4
20diencephalic astrocytomas10.4BRAF, NF1
21pseudoachondroplastic dysplasia 210.4PTPN11, RAF1
22cerebritis10.4
23leukemia10.4
24cataract-intellectual disability-hypogonadism syndrome10.4BRAF, KRAS
25prostate cancer10.4
26prostatitis10.4
27eccrine papillary adenoma10.3BRAF, KRAS
28ovarian germ cell teratoma10.3BRAF, KRAS
29breast cancer10.3
30obesity10.3
31lymphoma10.3
32endotheliitis10.3
33angiodysplasia of intestine10.3KRAS, RAF1
34nuclear gene-encoded leigh syndrome10.3BRAF, PTPN11, RAF1
35reproductive organ benign neoplasm10.3KRAS, RAF1
36metachondromatosis10.3BRAF, PTPN11, RAF1
37rad21-related cornelia de lange syndrome10.3BRAF, PTPN11, RAF1
38western equine encephalitis10.3KRAS, RAF1
39in situ pulmonary adenocarcinoma10.3BRAF, KRAS
40splenogonadal fusion limb defects micrognatia10.2BRAF, HRAS
41myocardial infarction10.2
42b-cell lymphomas10.2
43q fever10.2
44pyelonephritis10.2
45melanoma10.2
46thyroiditis10.2
47hypoxia10.2
48childhood central nervous system mature teratoma10.2JAG1, PTPN11
49pineal region germinoma10.2MAP2K1, MAP2K2
50rheumatoid arthritis10.2

Graphical network of the top 20 diseases related to Pulmonic Stenosis:



Diseases related to pulmonic stenosis

Symptoms for Pulmonic Stenosis

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HPO human phenotypes related to Pulmonic Stenosis:

id Description Frequency HPO Source Accession
1 abnormality of the pulmonary artery hallmark (90%) HP:0004414
2 atria septal defect typical (50%) HP:0001631
3 pulmonic stenosis HP:0001642

Drugs & Therapeutics for Pulmonic Stenosis

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Drugs for Pulmonic Stenosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MinoxidilapprovedPhase 23338304-91-54201
Synonyms:
16317-69-4
2,3-Dihydro-3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine
2,4-Diamino-6-piperidinilpirimidina-3-ossido
2,4-Diamino-6-piperidinilpirimidina-3-ossido [Italian]
2,4-Diamino-6-piperidino-pyrimidine-3-oxide
2,4-Diamino-6-piperidinopyrimidine 3-N-oxide
2,4-Diamino-6-piperidinopyrimidine 3-oxide
2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide
2,6-Diamino-4-piperidinopyrimidin-1-oxid
3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine
3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
38304-91-5
5-25-12-00317 (Beilstein Handbook Reference)
6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
6-(piperidin-1-yl)pyrimidine-2,4-diamine 3-oxide
6-Amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine
6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide
6-Piperidino-2,4-diaminopyrimidine 3-oxide
6-[1-Piperidinyl]pyrimidine-2,4-diamine 3 oxide
AB00513797
AC-5271
AC1L1HN1
Alopexil
Alostil
Ambap38304-91-5
Apo-Gain
Apo-gain
BCBcMAP01_000193
BPBio1_000065
BRD-K06902185-001-05-2
BRD-K14888893-001-02-3
BRN 0886240
BSPBio_000059
BSPBio_001385
BSPBio_002037
Bio1_000084
Bio1_000573
Bio1_001062
Bio2_000105
Bio2_000585
Boost Regrowth For Women
Bosley Professional Strength Hair Regrowth Treatment Regular Strength For Men
Bosley Professional Strength Hair Regrowth Treatment Regular Strength For Women
C9H15N5.H2O
CAS-38304-91-5
CBiol_001798
CHEBI:49774
CHEBI:6942
CHEMBL609587
CHEMBL802
CID4201
CPD-7668
CPD000058963
Careone Hair Regrowth Treatment
Careone Hair Regrowth Treatment Extra Strength
Cerafill Retaliate
Cerafill Retaliate Extra Strength For Men
D00418
D008914
DB00350
DB08225
DivK1c_000160
EINECS 253-874-2
EU-0100786
Equaline Hair Regrowth Treatment For Men
Equaline Hair Regrowth Treatment For Women
Equaline Hair Regrowth Treatment for men
Equaline Hair Regrowth Treatment for women
Equate Hair Regrowth Treatment
Equate Hair Regrowth Treatment for men
Equate Hair Regrowth Treatment for women
Gen-Minoxidil
Good Neighbor Pharmacy Hair Regrowth Treatment For Men
Good Sense Hair Regrowth Treatment
Good Sense Hair Regrowth Treatment for Men
Good Sense Hair Regrowth Treatment for women
HMS1361F07
HMS1568C21
HMS1791F07
HMS1920P03
HMS1989F07
HMS2089L08
HMS2091F20
HMS500H22
HSDB 6538
Hair Regrowth Treatment
Hair Regrowth Treatment Extra Strength for Men
Hair Regrowth Treatment For Men
Hair Regrowth Treatment For Men Extra Strength
Hair Regrowth Treatment For Women
Hair Regrowth Treatment for women
Hair Regrowth treatment for men
Hair Regrowth treatment for women
Harmon Face Values Minoxidil
IDI1_000160
IDI1_033855
Image Essentials Hair Regrowth Treatment
Image Essentials Hair Regrowth Treatment For Men
Jsp006715
KBio1_000160
KBio2_000105
KBio2_001449
KBio2_002673
KBio2_004017
KBio2_005241
KBio2_006585
KBio3_000209
KBio3_000210
KBio3_001537
KBioGR_000105
KBioGR_000585
KBioSS_000105
KBioSS_001449
Keranique For Women Hair Regrowth Treatment
Kirkland Signature Minoxidil
LS-135040
Leader Hair Regrowth Treatment
Loesch Hair Regrowth Formula Unscented Topical Solution Extra-Strength for Men
 
Loniten
Loniten (TN)
Lonolox
Lopac-M-4145
Lopac0_000786
M 4145
M1389
MINOXIDIL (FOR MEN)
MINOXIDIL (FOR WOMEN)
MINOXIDIL EXTRA STRENGTH (FOR MEN)
MINOXIDIL EXTRA STRENGTH FOR MEN
MLS000028566
MLS000859953
MLS001077294
Men s Rogaine Foam
Men's Rogaine
Mens Comback Hair Regrowth Treatment Extra Strength Unscented
Mens Hair Regrowth Treatment extra strength
Mens Kirkland Extra Strength
Mens Rogaine Extra Strength
Mens Rogaine Foam
Mens Rogaine Unscented Formula
Minodyl
Minossidile
Minossidile [Italian]
Minoxidil
Minoxidil (USP/INN)
Minoxidil Foam
Minoxidil For Women
Minoxidil Form Men extra strength
Minoxidil Pfizer Brand
Minoxidil [USAN:BAN:INN]
Minoxidil for men
Minoxidil for women
Minoxidil regular strength
Minoxidilum
Minoxidilum [INN-Latin]
Minoxigaine
Minoximen
MolPort-003-666-236
MolPort-005-932-694
NCGC00015673-01
NCGC00015673-02
NCGC00015673-04
NCGC00015673-11
NCGC00018278-01
NCGC00024666-01
NCGC00024666-02
NCGC00024666-03
NCGC00024666-04
NCGC00024666-05
NCGC00024666-06
NCGC00024666-07
NCGC00024666-08
NCGC00179672-01
NINDS_000160
Neoxidil
Nioxin Hair Regrowth Treatment Extra Strength For Men
Nioxin Hair Regrowth Treatment For Women
Normoxidil
Pantene Pro-v Expert Collection Hair Regrowth Treatment for Women
Pfizer Brand of Minoxidil
Pierminox
Prestwick0_000020
Prestwick1_000020
Prestwick2_000020
Prestwick3_000020
Prestwick_521
Prexidil
Pyrimidine, 2,4-diamino-6-piperidino-, 3-oxide
ROGAINE (FOR MEN)
ROGAINE (FOR WOMEN)
ROGAINE EXTRA STRENGTH (FOR MEN)
Re-gro
Regaine
Renewal For Men
RiUP
Riup (TN)
Rogaine
Rogaine (TN)
Rogaine Extra Strength for Men
Rogaine for Men
Rogaine for Women
Rogaine, Regaine, Avacor and Mintop, Minoxidil
S1383_Selleck
SAM002589949
SBB056986
SGCUT00112
SMP1_000192
SMR000058963
SMR000326812
SPBio_001006
SPBio_001980
SPECTRUM1500415
Simply Right Minoxidil
Simply Right Minoxidil extra strength
Solution
Spectrum2_001053
Spectrum3_000509
Spectrum4_000063
Spectrum5_001299
Spectrum_000969
TM-160
Theroxidil
Tocris-0583
Toppik Mens Hair Regrowth Treatment Extra Strength
Toppik Womens Hair Regrowth Treatment
Tricoxidil
Trocoxidil
U 10858
U-10,858
U-10858
Vanarex Hair Regrowth Treatment
Womens Rogaine - Unscented
Womens Rogaine Unscented
ZINC00001735
minoxidil
nchembio.79-comp10
to_000070
2
Sirolimusapproved, investigationalPhase 2179753123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
3
Miconazoleapproved, investigationalPhase 2302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
4
EverolimusapprovedPhase 21797159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
Afinitor Disperz
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
VOTUBIA
Zortress
everolimus
5Antihypertensive AgentsPhase 23618
6Vasodilator AgentsPhase 22926
7Antibiotics, AntitubercularPhase 25971
8Anti-Bacterial AgentsPhase 29140
9Immunosuppressive AgentsPhase 210422
10Immunologic FactorsPhase 218483
11Antifungal AgentsPhase 23015
12Anti-Infective AgentsPhase 217220
13Hormones11748
14Calcium, Dietary4678
15CitrateNutraceutical1001
16
Citric Acidnutraceutical100177-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid

Interventional clinical trials:

(show all 22)
idNameStatusNCT IDPhase
1Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve DysfunctionNot yet recruitingNCT02744677Phase 3
2Efficacy of Minoxidil in Children With Williams-Beuren SyndromeCompletedNCT00876200Phase 2
3Systemic Rapamycin (Sirolimus) to Prevent In-Stent Restenosis Following Pulmonary Artery Stent PlacementRecruitingNCT02365415Phase 2
4A Feasibility Study to Evaluate the Safety and Short-term Effectiveness of Transcatheter Pulmonary Valve (TPV)RecruitingNCT02555319Phase 2
5Pulmonary Arteriopathy-Diagnostics and TherapyCompletedNCT00266175
6Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac DefectsCompletedNCT00004361
7Reproduction and Survival After Cardiac Defect RepairCompletedNCT00005190
8CryoValve SG Pulmonary Human Heart Valve Post Clearance StudyCompletedNCT01092442
9Retrospective Pulmonary Valve Replacement ImagingCompletedNCT00446108
10Early Re-intervention in Infants and Small Children After Correction of Tetralogy of FallotCompletedNCT00536432
11A Study of Strategies for Electrical Isolation of Pulmonic Veins for Curative Treatment of Atrial FibrillationCompletedNCT00434694
12Right and Left Ventricle Remodeling Predictors After Pulmonary Valve Replacement in Patients With Repaired Tetralogy of FallotRecruitingNCT02186691
13Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue BankRecruitingNCT02706639
14Pulmonic Valve REplacement Multi-discIpline EMEA RegistryActive, not recruitingNCT01356108
15COMPASSION: COngenital Multicenter Trial of Pulmonic VAlve Regurgitation Studying the SAPIEN InterventIONal THVActive, not recruitingNCT00676689
16Pulmonary Artery Repair With Covered StentsActive, not recruitingNCT01824160
17Follow Up on Freestyle Valves in ChildrenActive, not recruitingNCT00385112
18Behaviour of Tricuspid Valve Regurgitation in Volume and/or Pressure Loaded Right HeartNot yet recruitingNCT01444222
19Study to Assess Safety of the Pulmonary Valved Conduit (PV-001) in Subjects Undergoing Right Ventricular Outflow Tract ReconstructionNot yet recruitingNCT02700100
20Hormonal Sensitivity in Patients With Noonan and LEOPARD SyndromesNot yet recruitingNCT02486731
21Mild Valvar Pulmonary StenosisTerminatedNCT00277927
22Adult Pulmonary Valve Replacement: A Simple and Reproducible TechniqueTerminatedNCT00384163

Search NIH Clinical Center for Pulmonic Stenosis

Inferred drug relations via UMLS65/NDF-RT43:

Genetic Tests for Pulmonic Stenosis

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Anatomical Context for Pulmonic Stenosis

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MalaCards organs/tissues related to Pulmonic Stenosis:

33
Heart, Breast, Bone, Prostate, Brain, Endothelial, Liver

Animal Models for Pulmonic Stenosis or affiliated genes

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MGI Mouse Phenotypes related to Pulmonic Stenosis:

38 (show all 28)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.3BRAF, KRAS, NF1, NR2F2, PTPN11
2MP:00053898.4BRAF, IGFBP7, KRAS, MAP2K1, NR2F2, PTPN11
3MP:00053708.4BRAF, JAG1, KRAS, NF1, PTPN11, RAF1
4MP:00053888.2BRAF, HRAS, KRAS, NF1, PTPN11, RAF1
5MP:00030128.1HRAS, IGFBP7, JAG1, KRAS, NR2F2, PTPN11
6MP:00020068.0BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
7MP:00053807.6BRAF, JAG1, KRAS, MAP2K1, NF1, NR2F2
8MP:00053697.6BRAF, DTNA, JAG1, KRAS, NF1, NR2F2
9MP:00053817.4BRAF, JAG1, KRAS, MAP2K1, MAP2K2, NF1
10MP:00053777.4BRAF, JAG1, KRAS, MAP2K1, MAP2K2, NF1
11MP:00053917.2BRAF, JAG1, KRAS, MAP2K1, MAP2K2, NF1
12MP:00107717.2BRAF, HRAS, IGFBP7, JAG1, KRAS, MAP2K1
13MP:00053847.2BRAF, IGFBP7, JAG1, KRAS, MAP2K1, MAP2K2
14MP:00053767.0BRAF, HRAS, JAG1, KRAS, MAP2K1, MAP2K2
15MP:00028736.9BRAF, HRAS, JAG1, KRAS, MAP2K1, MAP2K2
16MP:00053866.9BRAF, DTNA, HRAS, IGFBP7, JAG1, KRAS
17MP:00053796.9BRAF, HRAS, IGFBP7, JAG1, KRAS, MAP2K1
18MP:00053826.8BRAF, HRAS, JAG1, KRAS, MAP2K1, MAP2K2
19MP:00036316.1BRAF, DTNA, HRAS, JAG1, KRAS, MAP2K1
20MP:00053905.8BRAF, DTNA, HRAS, JAG1, KRAS, MAP2K1
21MP:00107685.6BRAF, DTNA, HRAS, JAG1, KRAS, MAP2K1
22MP:00053855.6BRAF, DTNA, HRAS, JAG1, KRAS, MAP2K1
23MP:00053785.3BRAF, DTNA, HRAS, IGFBP7, JAG1, KRAS

Publications for Pulmonic Stenosis

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Articles related to Pulmonic Stenosis:

(show top 50)    (show all 331)
idTitleAuthorsYear
1
Xyloglucan for the Treatment of Acute Gastroenteritis in Children: Results of a Randomized, Controlled, Clinical Trial. (27212943)
2016
2
Successful treatment of scleromyxedema with melphalan and dexamethasone followed by thalidomide maintenance therapy. (27118492)
2016
3
Extrauterine choriocarcinoma: another uncommon primary pelvic retroperitoneal mass seen in adults. (23322843)
2013
4
Ultrasonography-guided central venous catheterisation in haematological patients with severe thrombocytopenia. (23399356)
2013
5
The significance of IDH1 mutations in tumor-associated seizure in 60 Chinese patients with low-grade gliomas. (24324372)
2013
6
Elevated expression of hyaluronic acid binding protein 1 (HABP1)/P32/C1QBP is a novel indicator for lymph node and peritoneal metastasis of epithelial ovarian cancer patients. (23929393)
2013
7
siRNA targeting survivin inhibits the growth and enhances the chemosensitivity of hepatocellular carcinoma cells. (23254641)
2013
8
Factors associated with asymptomatic infection in family members and neighbors of patients with visceral leishmaniasis. (23288063)
2012
9
Performance of frontloading for smear microscopy in the diagnosis of pulmonary tuberculosis: a cross-sectional study at a referral hospital in Uganda. (23144768)
2012
10
Lateralized response of dynorphin a peptide levels after traumatic brain injury. (22468884)
2012
11
The possible role of neuropeptide Y after spontaneous subarachnoid hemorrhage. (21626172)
2011
12
Gastrointestinal stromal tumor presenting as a rectovaginal mass. Clinicopathologic and molecular-genetic characterization of a rare tumor with a literature review. (21237497)
2011
13
Prevalent mutations of human prion protein: a molecular modeling and molecular dynamics study. (21875156)
2011
14
Early prenatal ventriculomegaly due to an AIFM1 mutation identified by linkage analysis and whole exome sequencing. (22019070)
2011
15
Molecular markers and bladder carcinoma: Schistosomal and non-schistosomal. (20934419)
2011
16
Brain metastases from lung cancer responding to erlotinib: the importance of EGFR mutation. (20595147)
2011
17
Combined staged endoscopic and microsurgical approach of a third ventricular choroid plexus papilloma in an infant. (22278793)
2011
18
Genetic variation in the beta2-adrenergic receptor but not catecholamine-O-methyltransferase predisposes to chronic pain: results from the 1958 British Birth Cohort Study. (20167428)
2010
19
In vitro determination of tetanus toxicity by an endopeptidase assay linked to a ganglioside-binding step. (20036726)
2010
20
Mixed Candida albicans and Candida glabrata populations associated with the pathogenesis of denture stomatitis. (18793360)
2008
21
Co-existence of common variable immunodeficiency (CVID) with idiopathic thrombocytopenic purpura (ITP). (18319527)
2008
22
Small interfering RNA-mediated silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase enhances the sensitivity of HeLa cells toward tumor necrosis factor-alpha and anticancer drugs. (17854715)
2007
23
MECT1-MAML2 fusion transcript defines a favorable subset of mucoepidermoid carcinoma. (16818685)
2006
24
Cytochrome P-450 4F18 is the leukotriene B4 omega-1/omega-2 hydroxylase in mouse polymorphonuclear leukocytes: identification as the functional orthologue of human polymorphonuclear leukocyte CYP4F3A in the down-regulation of responses to LTB4. (16380383)
2006
25
Methionine adenosyltransferase and S-adenosylmethionine in alcoholic liver disease. (16958675)
2006
26
Progression of secondary hyperparathyroidism involves deregulation of genes related to DNA and RNA stability. (15882268)
2005
27
Hydrogen peroxide induced apoptosis in amnion-derived WISH cells is not inhibited by vitamin C. (15028418)
2004
28
Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease. (14991845)
2004
29
GATA factors differentially activate multiple gonadal promoters through conserved GATA regulatory elements. (11181509)
2001
30
Recent developments in staphylococcal scalded skin syndrome. (11442563)
2001
31
Chromosome condensation by a human condensin complex in Xenopus egg extracts. (11136719)
2001
32
Cutaneous anthrax in eastern Turkey. (11419020)
2001
33
Differential age-related changes of hypothalamus - pituitary - adrenal axis hormones in healthy women and men - role of interleukin 6. (11341305)
2001
34
Identification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1. (10970861)
2000
35
Cyclin D1 suppresses retinoblastoma protein-mediated inhibition of TAFII250 kinase activity. (11126356)
2000
36
A nuclear receptor system constituted by RAR and RXR induces aromatase activity in MCF-7 human breast cancer cells. (10996432)
2000
37
Primary hemangiopericytoma of the superior mediastinum: a case report. (9828288)
1998
38
Comparative analysis of antibody and cell-mediated autoimmunity to transaldolase and myelin basic protein in patients with multiple sclerosis. (9077532)
1997
39
Mouse clavicular development: analysis of wild-type and cleidocranial dysplasia mutant mice. (9286593)
1997
40
On the role of the invariant glutamine at position 54 in the human choriogonadotropin beta subunit. (7531278)
1994
41
Cardiac thrombi--plasma protein C deficiency as a possible risk factor. (8456032)
1993
42
Orbital disease. (1639592)
1992
43
Protein kinase C in normal human epidermal keratinocytes during proliferation and calcium-induced differentiation. (1431218)
1992
44
Cyclical mastalgia as a marker of breast cancer susceptibility: results of a case-control study among French women. (1616869)
1992
45
Minisatellite binding protein Msbp-1 is a sequence-specific single-stranded DNA-binding protein. (1754375)
1991
46
Antagonism of the effects of calcitonin gene-related peptide and of capsaicin on the guinea-pig isolated ileum by human alpha-calcitonin gene-related peptide(8-37). (1922967)
1991
47
Identification of antisense transcripts of the chicken insulin-like growth factor-II gene. (1930626)
1991
48
Favism in childhood; a case report. (14884561)
1951
49
Congenital heart disease associated with subdiaphragmatic lateral heterotaxy. (15411467)
1950
50

Variations for Pulmonic Stenosis

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Expression for genes affiliated with Pulmonic Stenosis

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Search GEO for disease gene expression data for Pulmonic Stenosis.

Pathways for genes affiliated with Pulmonic Stenosis

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Pathways related to Pulmonic Stenosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 150)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
8.9BRAF, MAP2K1, MAP2K2, NF1, RAF1
2
Show member pathways
8.8HRAS, MAP2K1, PTPN11, RAF1
38.8HRAS, MAP2K1, MAP2K2, RAF1
48.7BRAF, KRAS, MAP2K1, MAP2K2, RAF1
58.7BRAF, KRAS, MAP2K1, MAP2K2, RAF1
68.6BRAF, HRAS, IGFBP7, MAP2K1, RAF1
78.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
8
Show member pathways
8.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
9
Show member pathways
8.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
108.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
118.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
12
Show member pathways
8.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
138.4HRAS, KRAS, MAP2K2, PTPN11, RAF1
148.4HRAS, KRAS, MAP2K1, PTPN11, RAF1
158.4BRAF, HRAS, KRAS, MAP2K1, MAP2K2
16
Show member pathways
8.3BRAF, HRAS, KRAS, MAP2K1, MAP2K2
17
Show member pathways
8.3HRAS, KRAS, MAP2K1, MAP2K2, RAF1
188.3HRAS, KRAS, MAP2K1, MAP2K2, RAF1
19
Show member pathways
8.3HRAS, KRAS, MAP2K1, MAP2K2, RAF1
208.3HRAS, KRAS, MAP2K1, MAP2K2, RAF1
218.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
22
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
23
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
248.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
258.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
26
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
27
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
28
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
29
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
30
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
31
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
32
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
33
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
34
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
358.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
36
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
37
Show member pathways
8.0HRAS, KRAS, MAP2K1, MAP2K2, PTPN11, RAF1
38
Show member pathways
8.0HRAS, KRAS, MAP2K1, MAP2K2, PTPN11, RAF1
398.0HRAS, KRAS, MAP2K1, MAP2K2, PTPN11, RAF1
407.8HRAS, KRAS, MAP2K1, MAP2K2, RAF1, ZIC3
417.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
427.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
43
Show member pathways
7.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
44
Show member pathways
7.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
457.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
46
Show member pathways
7.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
47
Show member pathways
7.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
48
Show member pathways
7.5BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
49
Show member pathways
7.5BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
50
Show member pathways
6.6BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1

GO Terms for genes affiliated with Pulmonic Stenosis

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Biological processes related to Pulmonic Stenosis according to GeneCards Suite gene sharing:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of axonogenesisGO:005077210.5BRAF, MAP2K1
2forebrain astrocyte developmentGO:002189710.4KRAS, NF1
3cerebellar cortex formationGO:002169710.4MAP2K1, PTPN11
4epithelial cell proliferation involved in lung morphogenesisGO:006050210.4MAP2K1, MAP2K2
5negative regulation of endothelial cell proliferationGO:000193710.4NF1, NR2F2
6regulation of synaptic transmission, GABAergicGO:003222810.3KRAS, NF1
7placenta blood vessel developmentGO:006067410.3MAP2K1, NR2F2
8cell communicationGO:000715410.3JAG1, NF1
9keratinocyte differentiationGO:003021610.2JAG1, MAP2K1
10regulation of axon regenerationGO:004867910.1BRAF, MAP2K1, MAP2K2
11positive regulation of protein serine/threonine kinase activityGO:007190210.0MAP2K1, MAP2K2
12cellular senescenceGO:009039810.0HRAS, MAP2K1
13ERBB2 signaling pathwayGO:00381289.9HRAS, KRAS
14activation of MAPK activityGO:00001879.9MAP2K1, MAP2K2, PTPN11
15thymus developmentGO:00485389.7BRAF, MAP2K1, MAP2K2, RAF1
16negative regulation of neuron apoptotic processGO:00435249.7BRAF, HRAS, KRAS
17Ras protein signal transductionGO:00072659.6BRAF, MAP2K1, MAP2K2, RAF1
18MAPK cascadeGO:00001659.5HRAS, KRAS, NF1
19negative regulation of gene expressionGO:00106299.4HRAS, MAP2K1, MAP2K2
20regulation of cell proliferationGO:00421279.3BRAF, JAG1, NF1
21leukocyte migrationGO:00509009.3HRAS, KRAS, PTPN11
22synaptic transmissionGO:00072689.1DTNA, HRAS, RAF1
23regulation of long-term neuronal synaptic plasticityGO:00481699.1HRAS, KRAS, NF1
24axon guidanceGO:00074119.0BRAF, HRAS, KRAS, RAF1
25epidermal growth factor receptor signaling pathwayGO:00071738.3BRAF, HRAS, KRAS, MAP2K1, NF1, PTPN11
26neurotrophin TRK receptor signaling pathwayGO:00480118.2BRAF, HRAS, KRAS, MAP2K1, NF1, RAF1
27activation of MAPKK activityGO:00001868.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
28vascular endothelial growth factor receptor signaling pathwayGO:00480108.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
29fibroblast growth factor receptor signaling pathwayGO:00085437.9BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
30insulin receptor signaling pathwayGO:00082867.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
31signal transductionGO:00071657.5BRAF, DTNA, HRAS, NF1, NR2F2, RAF1
32innate immune responseGO:00450877.5BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1

Sources for Pulmonic Stenosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet