Aliases & Classifications for Pulmonic Stenosis

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Aliases & Descriptions for Pulmonic Stenosis:

Name: Pulmonic Stenosis 45
Valvular Pulmonic Stenosis 45
 
Pulmonary Valve Stenosis 65
Pulmonary Stenosis 65


Classifications:



Summaries for Pulmonic Stenosis

About this section
Wikipedia:68 Pulmonic stenosis, also known as pulmonary stenosis, is a dynamic or fixed obstruction of flow from the... more...

MalaCards based summary: Pulmonic Stenosis, also known as valvular pulmonic stenosis, is related to watson syndrome and leopard syndrome 1, and has symptoms including abnormality of the pulmonary artery, atria septal defect and pulmonic stenosis. An important gene associated with Pulmonic Stenosis is BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways are G-protein signaling M-RAS regulation pathway and Development_Leptin signaling via JAK/STAT and MAPK cascades. The drug alprostadil has been mentioned in the context of this disorder. Affiliated tissues include heart, b cells and liver, and related mouse phenotypes are pigmentation and no phenotypic analysis.

Related Diseases for Pulmonic Stenosis

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Diseases related to Pulmonic Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 150)
idRelated DiseaseScoreTop Affiliating Genes
1watson syndrome30.8MAP2K2, NF1, PTPN11
2leopard syndrome 130.8BRAF, PTPN11, RAF1
3noonan syndrome 630.6PTPN11, RAF1
4costello syndrome29.9HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
5cardiofaciocutaneous syndrome29.7BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
6noonan syndrome 129.4BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
7retinal arterial macroaneurysm with supravalvular pulmonic stenosis10.8
8ventricular septal defect10.7
9tetralogy of fallot10.6
10mediastinitis10.5
11aneurysm10.5
12pulmonary hypertension10.5
13patent ductus arteriosus10.5
14keutel syndrome10.4
15congenital heart disease10.4
16heterotaxy, visceral, 1, x-linked10.3
17congestive heart failure10.3
18patent foramen ovale10.3
19pulmonary subvalvular stenosis10.3
20cerebellar disease10.3BRAF, NF1
21pseudoachondroplastic dysplasia 210.3PTPN11, RAF1
22her2-receptor negative breast cancer10.3BRAF, NF1
23cardiofaciocutaneous syndrome 310.3
24cardiofaciocutaneous syndrome 410.3
25cataract - intellectual disability - hypogonadism10.2BRAF, KRAS
26western equine encephalitis10.2KRAS, RAF1
27respiratory system disease10.2KRAS, RAF1
28nuclear gene-encoded leigh syndrome10.2BRAF, PTPN11, RAF1
29lung benign neoplasm10.2KRAS, RAF1
30eastern equine encephalitis10.2KRAS, RAF1
31mature teratoma of the ovary10.2BRAF, KRAS
32splenogonadal fusion limb defects micrognatia10.2BRAF, HRAS
33pupil disease10.1JAG1, PTPN11
34dwarfism10.1JAG1, PTPN11
35myocardial infarction10.1
36noonan syndrome 810.1
37prune belly syndrome10.1
38peters anomaly10.1
39noonan syndrome 410.1
40pitt-hopkins-like syndrome 210.1
41mowat-wilson syndrome10.1
42leopard syndrome 210.1
43chronic atrial and intestinal dysrhythmia10.1
44adams-oliver syndrome 110.1
45trichohepatoenteric syndrome 110.1
46supravalvar aortic stenosis10.1
47williams-beuren syndrome10.1
48charge syndrome10.1
49noonan syndrome 710.1
50leopard syndrome 310.1

Graphical network of the top 20 diseases related to Pulmonic Stenosis:



Diseases related to pulmonic stenosis

Symptoms for Pulmonic Stenosis

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HPO human phenotypes related to Pulmonic Stenosis:

id Description Frequency HPO Source Accession
1 abnormality of the pulmonary artery hallmark (90%) HP:0004414
2 atria septal defect typical (50%) HP:0001631
3 pulmonic stenosis HP:0001642

Drugs & Therapeutics for Pulmonic Stenosis

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Drugs for Pulmonic Stenosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MinoxidilapprovedPhase 23338304-91-54201
Synonyms:
16317-69-4
2,3-Dihydro-3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine
2,4-Diamino-6-piperidinilpirimidina-3-ossido
2,4-Diamino-6-piperidinilpirimidina-3-ossido [Italian]
2,4-Diamino-6-piperidino-pyrimidine-3-oxide
2,4-Diamino-6-piperidinopyrimidine 3-N-oxide
2,4-Diamino-6-piperidinopyrimidine 3-oxide
2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide
2,6-Diamino-4-piperidinopyrimidin-1-oxid
3-hydroxy-2-imino-6-(1-piperidyl)pyrimidin-4-amine
3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
38304-91-5
5-25-12-00317 (Beilstein Handbook Reference)
6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
6-(piperidin-1-yl)pyrimidine-2,4-diamine 3-oxide
6-Amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine
6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide
6-Piperidino-2,4-diaminopyrimidine 3-oxide
6-[1-Piperidinyl]pyrimidine-2,4-diamine 3 oxide
AB00513797
AC-5271
AC1L1HN1
Alopexil
Alostil
Ambap38304-91-5
Apo-Gain
Apo-gain
BCBcMAP01_000193
BPBio1_000065
BRD-K06902185-001-05-2
BRD-K14888893-001-02-3
BRN 0886240
BSPBio_000059
BSPBio_001385
BSPBio_002037
Bio1_000084
Bio1_000573
Bio1_001062
Bio2_000105
Bio2_000585
Boost Regrowth For Women
Bosley Professional Strength Hair Regrowth Treatment Regular Strength For Men
Bosley Professional Strength Hair Regrowth Treatment Regular Strength For Women
C9H15N5.H2O
CAS-38304-91-5
CBiol_001798
CHEBI:49774
CHEBI:6942
CHEMBL609587
CHEMBL802
CID4201
CPD-7668
CPD000058963
Careone Hair Regrowth Treatment
Careone Hair Regrowth Treatment Extra Strength
Cerafill Retaliate
Cerafill Retaliate Extra Strength For Men
D00418
D008914
DB00350
DB08225
DivK1c_000160
EINECS 253-874-2
EU-0100786
Equaline Hair Regrowth Treatment For Men
Equaline Hair Regrowth Treatment For Women
Equaline Hair Regrowth Treatment for men
Equaline Hair Regrowth Treatment for women
Equate Hair Regrowth Treatment
Equate Hair Regrowth Treatment for men
Equate Hair Regrowth Treatment for women
Gen-Minoxidil
Good Neighbor Pharmacy Hair Regrowth Treatment For Men
Good Sense Hair Regrowth Treatment
Good Sense Hair Regrowth Treatment for Men
Good Sense Hair Regrowth Treatment for women
HMS1361F07
HMS1568C21
HMS1791F07
HMS1920P03
HMS1989F07
HMS2089L08
HMS2091F20
HMS500H22
HSDB 6538
Hair Regrowth Treatment
Hair Regrowth Treatment Extra Strength for Men
Hair Regrowth Treatment For Men
Hair Regrowth Treatment For Men Extra Strength
Hair Regrowth Treatment For Women
Hair Regrowth Treatment for women
Hair Regrowth treatment for men
Hair Regrowth treatment for women
Harmon Face Values Minoxidil
IDI1_000160
IDI1_033855
Image Essentials Hair Regrowth Treatment
Image Essentials Hair Regrowth Treatment For Men
Jsp006715
KBio1_000160
KBio2_000105
KBio2_001449
KBio2_002673
KBio2_004017
KBio2_005241
KBio2_006585
KBio3_000209
KBio3_000210
KBio3_001537
KBioGR_000105
KBioGR_000585
KBioSS_000105
KBioSS_001449
Keranique For Women Hair Regrowth Treatment
Kirkland Signature Minoxidil
LS-135040
Leader Hair Regrowth Treatment
Loesch Hair Regrowth Formula Unscented Topical Solution Extra-Strength for Men
 
Loniten
Loniten (TN)
Lonolox
Lopac-M-4145
Lopac0_000786
M 4145
M1389
MINOXIDIL (FOR MEN)
MINOXIDIL (FOR WOMEN)
MINOXIDIL EXTRA STRENGTH (FOR MEN)
MINOXIDIL EXTRA STRENGTH FOR MEN
MLS000028566
MLS000859953
MLS001077294
Men s Rogaine Foam
Men's Rogaine
Mens Comback Hair Regrowth Treatment Extra Strength Unscented
Mens Hair Regrowth Treatment extra strength
Mens Kirkland Extra Strength
Mens Rogaine Extra Strength
Mens Rogaine Foam
Mens Rogaine Unscented Formula
Minodyl
Minossidile
Minossidile [Italian]
Minoxidil
Minoxidil (USP/INN)
Minoxidil Foam
Minoxidil For Women
Minoxidil Form Men extra strength
Minoxidil Pfizer Brand
Minoxidil [USAN:BAN:INN]
Minoxidil for men
Minoxidil for women
Minoxidil regular strength
Minoxidilum
Minoxidilum [INN-Latin]
Minoxigaine
Minoximen
MolPort-003-666-236
MolPort-005-932-694
NCGC00015673-01
NCGC00015673-02
NCGC00015673-04
NCGC00015673-11
NCGC00018278-01
NCGC00024666-01
NCGC00024666-02
NCGC00024666-03
NCGC00024666-04
NCGC00024666-05
NCGC00024666-06
NCGC00024666-07
NCGC00024666-08
NCGC00179672-01
NINDS_000160
Neoxidil
Nioxin Hair Regrowth Treatment Extra Strength For Men
Nioxin Hair Regrowth Treatment For Women
Normoxidil
Pantene Pro-v Expert Collection Hair Regrowth Treatment for Women
Pfizer Brand of Minoxidil
Pierminox
Prestwick0_000020
Prestwick1_000020
Prestwick2_000020
Prestwick3_000020
Prestwick_521
Prexidil
Pyrimidine, 2,4-diamino-6-piperidino-, 3-oxide
ROGAINE (FOR MEN)
ROGAINE (FOR WOMEN)
ROGAINE EXTRA STRENGTH (FOR MEN)
Re-gro
Regaine
Renewal For Men
RiUP
Riup (TN)
Rogaine
Rogaine (TN)
Rogaine Extra Strength for Men
Rogaine for Men
Rogaine for Women
Rogaine, Regaine, Avacor and Mintop, Minoxidil
S1383_Selleck
SAM002589949
SBB056986
SGCUT00112
SMP1_000192
SMR000058963
SMR000326812
SPBio_001006
SPBio_001980
SPECTRUM1500415
Simply Right Minoxidil
Simply Right Minoxidil extra strength
Solution
Spectrum2_001053
Spectrum3_000509
Spectrum4_000063
Spectrum5_001299
Spectrum_000969
TM-160
Theroxidil
Tocris-0583
Toppik Mens Hair Regrowth Treatment Extra Strength
Toppik Womens Hair Regrowth Treatment
Tricoxidil
Trocoxidil
U 10858
U-10,858
U-10858
Vanarex Hair Regrowth Treatment
Womens Rogaine - Unscented
Womens Rogaine Unscented
ZINC00001735
minoxidil
nchembio.79-comp10
to_000070
2
Miconazoleapproved, investigationalPhase 2291222916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
3
Sirolimusapproved, investigationalPhase 2174253123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
4
EverolimusapprovedPhase 21742159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
Afinitor Disperz
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
VOTUBIA
Zortress
everolimus
5Calcium, Dietary3529
6
Citric Acidnutraceutical78477-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
7CitrateNutraceutical784

Interventional clinical trials:

(show all 19)
idNameStatusNCT IDPhase
1Efficacy of Minoxidil in Children With Williams-Beuren SyndromeCompletedNCT00876200Phase 2
2Systemic Rapamycin (Sirolimus) to Prevent In-Stent Restenosis Following Pulmonary Artery Stent PlacementRecruitingNCT02365415Phase 2
3A Feasibility Study to Evaluate the Safety and Short-term Effectiveness of Transcatheter Pulmonary Valve (TPV)Not yet recruitingNCT02555319Phase 2
4Pulmonary Arteriopathy-Diagnostics and TherapyCompletedNCT00266175
5Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac DefectsCompletedNCT00004361
6Reproduction and Survival After Cardiac Defect RepairCompletedNCT00005190
7CryoValve SG Pulmonary Human Heart Valve Post Clearance StudyCompletedNCT01092442
8Retrospective Pulmonary Valve Replacement ImagingCompletedNCT00446108
9Early Re-intervention in Infants and Small Children After Correction of Tetralogy of FallotCompletedNCT00536432
10A Study of Strategies for Electrical Isolation of Pulmonic Veins for Curative Treatment of Atrial FibrillationCompletedNCT00434694
11Right and Left Ventricle Remodeling Predictors After Pulmonary Valve Replacement in Patients With Repaired Tetralogy of FallotRecruitingNCT02186691
12Pulmonic Valve REplacement Multi-discIpline EMEA RegistryActive, not recruitingNCT01356108
13COMPASSION: COngenital Multicenter Trial of Pulmonic VAlve Regurgitation Studying the SAPIEN InterventIONal THVActive, not recruitingNCT00676689
14Pulmonary Artery Repair With Covered StentsActive, not recruitingNCT01824160
15Follow Up on Freestyle Valves in ChildrenActive, not recruitingNCT00385112
16Behaviour of Tricuspid Valve Regurgitation in Volume and/or Pressure Loaded Right HeartNot yet recruitingNCT01444222
17Hormonal Sensitivity in Patients With Noonan and LEOPARD SyndromesNot yet recruitingNCT02486731
18Mild Valvar Pulmonary StenosisTerminatedNCT00277927
19Adult Pulmonary Valve Replacement: A Simple and Reproducible TechniqueTerminatedNCT00384163

Search NIH Clinical Center for Pulmonic Stenosis

Inferred drug relations via UMLS65/NDF-RT43:

Genetic Tests for Pulmonic Stenosis

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Anatomical Context for Pulmonic Stenosis

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MalaCards organs/tissues related to Pulmonic Stenosis:

33
Heart, B cells, Liver, Lung

Animal Models for Pulmonic Stenosis or affiliated genes

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MGI Mouse Phenotypes related to Pulmonic Stenosis:

38 (show all 27)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.4BRAF, KRAS, NF1, NR2F2, PTPN11
2MP:00030128.6HRAS, IGFBP7, JAG1, NR2F2, PTPN11, RAF1
3MP:00053718.6DTNA, KRAS, NF1, PTPN11, ZIC3
4MP:00053778.5JAG1, MAP2K1, MAP2K2, NF1, PTPN11, ZIC3
5MP:00053708.3BRAF, JAG1, KRAS, NF1, PTPN11, RAF1
6MP:00053888.2BRAF, HRAS, KRAS, NF1, PTPN11, RAF1
7MP:00053848.0BRAF, JAG1, KRAS, MAP2K1, MAP2K2, NF1
8MP:00020067.9BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
9MP:00053817.8BRAF, JAG1, KRAS, MAP2K1, MAP2K2, NR2F2
10MP:00053697.6BRAF, DTNA, JAG1, KRAS, NF1, NR2F2
11MP:00053807.5BRAF, JAG1, KRAS, MAP2K1, NF1, NR2F2
12MP:00053827.4BRAF, HRAS, JAG1, MAP2K1, MAP2K2, NF1
13MP:00107717.4BRAF, HRAS, JAG1, KRAS, MAP2K1, MAP2K2
14MP:00053917.1BRAF, JAG1, KRAS, MAP2K1, MAP2K2, NF1
15MP:00053867.1BRAF, DTNA, HRAS, JAG1, KRAS, NF1
16MP:00028736.9BRAF, HRAS, JAG1, KRAS, MAP2K1, MAP2K2
17MP:00053766.8BRAF, HRAS, JAG1, KRAS, MAP2K1, MAP2K2
18MP:00053796.6BRAF, HRAS, JAG1, KRAS, MAP2K1, MAP2K2
19MP:00053906.6BRAF, DTNA, HRAS, JAG1, MAP2K1, MAP2K2
20MP:00053856.1BRAF, DTNA, HRAS, JAG1, KRAS, MAP2K1
21MP:00036316.0BRAF, DTNA, HRAS, JAG1, KRAS, MAP2K1
22MP:00107685.7BRAF, DTNA, HRAS, JAG1, KRAS, MAP2K1
23MP:00053785.7BRAF, DTNA, HRAS, JAG1, KRAS, MAP2K1

Publications for Pulmonic Stenosis

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Articles related to Pulmonic Stenosis:

(show top 50)    (show all 326)
idTitleAuthorsYear
1
Prevalence of patent foramen ovale with right-to-left shunting in dogs with pulmonic stenosis. (22151278)
2012
2
Massive dilatation of the pulmonary artery in association with pulmonic stenosis and pulmonary hypertension. (22837867)
2012
3
The relevance of echocardiography heart measures for breeding against the risk of subaortic and pulmonic stenosis in Boxer dogs. (21908643)
2012
4
Addition of color Doppler to the routine obstetric sonographic survey aids in the detection of pulmonic stenosis. (20720393)
2010
5
Partial anomalous pulmonary venous return presenting as pseudo-pulmonic stenosis. (19083893)
2007
6
Balloon valvuloplasty of valvular pulmonic stenosis in the dog. (16180401)
2005
7
ECG of the month. Pulmonic stenosis. (15154725)
2004
8
Pulmonic stenosis in dogs: balloon dilation improves clinical outcome. (15515581)
2004
9
Branchio-oculo-facial syndrome with valvular pulmonic stenosis. (15591681)
2004
10
Pathogenesis of single right coronary artery and pulmonic stenosis in English Bulldogs. (11300591)
2001
11
Pulmonic stenosis caused by single coronary artery in dogs: four cases (1965-1984). (2295544)
1990
12
Management of neonatal critical pulmonic stenosis in the balloon valvotomy era. (2306149)
1990
13
Pannus formation in a Hancock-valved conduit resulting in proximal intraconduit obstruction: late complication of Rastelli procedure for complete transposition of the great vessels with ventricular septal defect and pulmonic stenosis. (7234666)
1981
14
Congenital subvalvular pulmonic stenosis in a cat. (7190749)
1980
15
Frequency and direction of interatrial shunting in valvular pulmonic stenosis with intact ventricular septum and without left ventricular inflow or outflow obstruction. An analysis of 127 patients treated by valvulotomy. (7352396)
1980
16
Double-outlet right ventricle (S,D,D), VSD related to pulmonary artery, and pulmonic stenosis absent. Correction with an intraventricular conduit in infancy. (875443)
1977
17
Combined tricuspid and pulmonic stenosis. Clinical, echocardiographic, hemodynamic, surgical, and pathological features. (559886)
1977
18
USE OF AN EXTRACARDIAC CONDUIT IN THE REPAIR OF l-TRANSPOSITION WITH l-LOOPING ASSOCIATED WITH SEVERE SUBVALVULAR PULMONIC STENOSIS AND A VENTRICULAR SEPTAL DEFECT. (15216089)
1977
19
Giant blood cyst and congenital pulmonic stenosis. Report of a case. (1190181)
1975
20
Hypercyanotic spells (cyanotic crisis) in an infant with valvar pulmonic stenosis. (4768120)
1973
21
Pulmonic stenosis in the adult. Long-term follow-up results. (5082217)
1972
22
Myocardial infarction and pulmonic stenosis in a dog. (5105715)
1971
23
Pulmonary regurgitation with ventricular septal defect and pulmonic stenosis--tetralogy of Fallot variant. (5769310)
1969
24
Syphilitic aneurysm of the ascending aorta producing pulmonic stenosis by compression. (6052831)
1967
25
Dilatation of the aorta and pulmonary artery with aortic and pulmonary insufficiency in the presence of a ventricular septal defect and infundibular pulmonic stenosis. Report of a case of forme fruste of the Marfan syndrome. (5923672)
1966
26
EFFECT OF CHRONICALLY INCREASED VENTRICULAR PRESSURE ON ELECTRICAL FORCES OF THE HEART. A CORRELATION BETWEEN HEMODYNAMIC AND VECTROCARDIOGRAPHIC DATA (FRANK SYSTEM) IN 90 PATIENTS WITH AORTIC OR PULMONIC STENOSIS. (14211813)
1964
27
THE FATE OF THE PATIENT WITH PULMONIC STENOSIS. (14211817)
1964
28
CONGENITAL PULMONIC STENOSIS COMPLICATING EBSTEIN'S ANOMALY OF THE TRICUSPID VALVE. (14222416)
1964
29
LEFT SUPERIOR VENA CAVA WITH ANOMALOUS INFERIOR VENA CAVA. REPORT OF A CASE WITH ASSOCIATED ATRIAL SEPTAL DEFECT AND PULMONIC STENOSIS, SUCCESSFULLY CORRECTED. (14056243)
1963
30
Calcific pulmonic stenosis. (13938996)
1963
31
Combined aortic and pulmonic stenosis. (14477792)
1962
32
Acquired pulmonic stenosis. Report of a case caused by mediastinal neoplasm. (13965836)
1962
33
An electrographic study of right ventricular hypertrophy in pulmonic stenosis. (13606054)
1959
34
Valvular pulmonic stenosis: ausculatory and phonocardiographic characteristics. (13594834)
1958
35
Relative pulmonic stenosis. (13402715)
1957
36
Functional changes during high output failure produced by daily hemorrhage in dogs with pulmonic stenosis. (13447182)
1957
37
Experience in the surgical management of atrial septal defect and pulmonic stenosis under hypothermia. (13403184)
1957
38
Experiences in the surgical alleviation of congenital pulmonic stenosis. (14380099)
1955
39
Clinical and hemodynamic studies of congenital pulmonic stenosis with intact ventricular septum. (13171388)
1954
40
Hemodynamic effects of valvulotomy in pulmonic stenosis. (13082668)
1953
41
The problem of isolated valvular versus infundibular pulmonic stenosis with particular reference to cardiac catheterization data and records obtained at the time of operation. (13014127)
1953
42
The surgical treatment of pure pulmonic stenosis; a description of and expansible valvulotomy. (14855226)
1951
43
Changes in blood volume following operation for pulmonic stenosis: studies with Evans blue and radioactive phosphorus. (14869923)
1951
44
Aortic vascular rings encountered in the surgical treatment of congenital pulmonic stenosis. (15410299)
1950
45
Roentgenographic changes in pulmonic stenosis; a report of 9 cases. (15419338)
1950
46
The surgical treatment of congenital pulmonic stenosis. (20342447)
1947
47
The technique of creation of an artificial ductus arteriosus in the treatment of pulmonic stenosis. (20242212)
1947
48
The Blalock operation for congenital pulmonic stenosis; report of two successful cases. (20284738)
1947
49
The surgical treatment of congenital pulmonic stenosis. (21000853)
1946
50
Anesthesia in the surgical treatment of congenital pulmonic stenosis. (20996692)
1946

Variations for Pulmonic Stenosis

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Expression for genes affiliated with Pulmonic Stenosis

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Search GEO for disease gene expression data for Pulmonic Stenosis.

Pathways for genes affiliated with Pulmonic Stenosis

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Pathways related to Pulmonic Stenosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 144)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
8.9BRAF, MAP2K1, MAP2K2, NF1, RAF1
2
Show member pathways
8.8HRAS, MAP2K1, PTPN11, RAF1
38.8HRAS, MAP2K1, MAP2K2, RAF1
48.7BRAF, KRAS, MAP2K1, MAP2K2, RAF1
58.6BRAF, HRAS, IGFBP7, MAP2K1, RAF1
68.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
78.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
8
Show member pathways
8.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
98.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
10
Show member pathways
8.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
11
Show member pathways
8.5HRAS, MAP2K1, MAP2K2, PTPN11, RAF1
128.4HRAS, KRAS, MAP2K2, PTPN11, RAF1
138.4HRAS, KRAS, MAP2K1, PTPN11, RAF1
148.4BRAF, HRAS, KRAS, MAP2K1, MAP2K2
15
Show member pathways
8.3HRAS, KRAS, MAP2K1, MAP2K2, RAF1
168.3HRAS, KRAS, MAP2K1, MAP2K2, RAF1
17
TGF-beta Signaling Pathway (sino)
Show member pathways
8.3HRAS, KRAS, MAP2K1, MAP2K2, RAF1
188.3HRAS, KRAS, MAP2K1, MAP2K2, RAF1
198.3HRAS, KRAS, MAP2K1, MAP2K2, RAF1
208.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
21
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
22
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
23
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
24
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
25
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
26
VEGF Pathway (Tocris)
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
27
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
288.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
29
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
30
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
31
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
32
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
33
Show member pathways
8.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
348.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
358.1BRAF, HRAS, KRAS, MAP2K1, MAP2K2, RAF1
36
Show member pathways
8.0HRAS, KRAS, MAP2K1, MAP2K2, PTPN11, RAF1
378.0HRAS, KRAS, MAP2K1, MAP2K2, PTPN11, RAF1
387.8HRAS, KRAS, MAP2K1, MAP2K2, RAF1, ZIC3
397.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
407.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
41
Show member pathways
7.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
42
Show member pathways
7.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
43
Show member pathways
7.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
447.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
45
Show member pathways
7.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
46
Show member pathways
7.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
477.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, PTPN11
48
Show member pathways
7.5BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
49
Show member pathways
7.5BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
50
Show member pathways
6.6BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1

GO Terms for genes affiliated with Pulmonic Stenosis

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Cellular components related to Pulmonic Stenosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:00058297.2BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
2cytoplasmGO:00057376.1BRAF, DTNA, HRAS, KRAS, MAP2K1, MAP2K2

Biological processes related to Pulmonic Stenosis according to GeneCards Suite gene sharing:

(show all 38)
idNameGO IDScoreTop Affiliating Genes
1placenta blood vessel developmentGO:006067410.5MAP2K1, NR2F2
2trachea formationGO:006044010.4MAP2K1, MAP2K2
3epithelial cell proliferation involved in lung morphogenesisGO:006050210.4MAP2K1, MAP2K2
4regulation of Golgi inheritanceGO:009017010.4MAP2K1, MAP2K2
5regulation of stress-activated MAPK cascadeGO:003287210.4MAP2K1, MAP2K2
6regulation of early endosome to late endosome transportGO:200064110.4MAP2K1, MAP2K2
7lung morphogenesisGO:006042510.4MAP2K1, MAP2K2
8ERK1 and ERK2 cascadeGO:007037110.3MAP2K1, MAP2K2
9regulation of long-term neuronal synaptic plasticityGO:004816910.3HRAS, NF1
10regulation of axon regenerationGO:004867910.1BRAF, MAP2K1, MAP2K2
11positive regulation of axonogenesisGO:005077210.1BRAF, MAP2K1, MAP2K2
12cellular senescenceGO:009039810.1HRAS, MAP2K1
13positive regulation of Ras protein signal transductionGO:004657910.0HRAS, MAP2K1
14somatic stem cell population maintenanceGO:00350199.9BRAF, RAF1, ZIC3
15protein heterooligomerizationGO:00512919.8BRAF, HRAS, MAP2K1
16activation of MAPK activityGO:00001879.8MAP2K1, MAP2K2, PTPN11
17positive regulation of ERK1 and ERK2 cascadeGO:00703749.7BRAF, HRAS, PTPN11
18stimulatory C-type lectin receptor signaling pathwayGO:00022239.7HRAS, KRAS, RAF1
19positive regulation of protein phosphorylationGO:00019349.7HRAS, KRAS, RAF1
20leukocyte migrationGO:00509009.6HRAS, KRAS, PTPN11
21negative regulation of gene expressionGO:00106299.6HRAS, MAP2K1, MAP2K2
22organ morphogenesisGO:00098879.6BRAF, HRAS, JAG1
23negative regulation of cell proliferationGO:00082859.1HRAS, IGFBP7, MAP2K1, NF1, RAF1
24positive regulation of gene expressionGO:00106289.1BRAF, HRAS, KRAS, MAP2K1
25synaptic transmissionGO:00072688.8BRAF, DTNA, HRAS, RAF1
26MAPK cascadeGO:00001658.2BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
27activation of MAPKK activityGO:00001868.2BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
28Ras protein signal transductionGO:00072658.2BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
29insulin receptor signaling pathwayGO:00082867.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
30fibroblast growth factor receptor signaling pathwayGO:00085437.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
31Fc-epsilon receptor signaling pathwayGO:00380957.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
32neurotrophin TRK receptor signaling pathwayGO:00480117.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
33small GTPase mediated signal transductionGO:00072647.8BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
34vascular endothelial growth factor receptor signaling pathwayGO:00480107.7BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
35epidermal growth factor receptor signaling pathwayGO:00071737.6BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
36axon guidanceGO:00074117.5BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
37innate immune responseGO:00450877.5BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NF1
38signal transductionGO:00071656.7BRAF, DTNA, HRAS, KRAS, MAP2K1, NF1

Molecular functions related to Pulmonic Stenosis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1small GTPase bindingGO:003126710.7BRAF, RAF1
2mitogen-activated protein kinase kinase bindingGO:003143410.6BRAF, RAF1
3Ras GTPase bindingGO:001701610.5MAP2K1, RAF1
4MAP kinase kinase activityGO:000470810.4MAP2K1, MAP2K2
5protein serine/threonine kinase activator activityGO:004353910.3MAP2K1, MAP2K2
6protein serine/threonine kinase activityGO:00046749.6BRAF, MAP2K1, MAP2K2, RAF1
7protein bindingGO:00055155.0BRAF, DTNA, HRAS, IGFBP7, JAG1, KRAS

Sources for Pulmonic Stenosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet