MCID: PRP034
MIFTS: 46

Purpura Fulminans malady

Categories: Blood diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways Symptoms Drugs

Aliases & Classifications for Purpura Fulminans

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Aliases & Descriptions for Purpura Fulminans:

Name: Purpura Fulminans 10 47 36 65
 
Purpura Gangrenosa 10

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Blood diseases
See all MalaCards categories (disease lists)
ICD10: 27


External Ids:

Disease Ontology10 DOID:0060538
ICD1027 D65
MeSH36 D055665
UMLS65 C0085650

Summaries for Purpura Fulminans

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Disease Ontology:10 A purpura characterized blood spots, bruising and discolouration of the skin resulting from coagulation in small blood vessels within the skin and rapidly leads to skin necrosis and disseminated intravascular coagulation. It is often fatal.

MalaCards based summary: Purpura Fulminans, also known as purpura gangrenosa, is related to splenic abscess and protein s deficiency, and has symptoms including mucocutaneous haemorrhageand cullen's sign. An important gene associated with Purpura Fulminans is PROC (Protein C, Inactivator Of Coagulation Factors Va And VIIIa), and among its related pathways are Warfarin Pathway, Pharmacodynamics and Gamma carboxylation, hypusine formation and arylsulfatase activation. Affiliated tissues include skin, breast and liver, and related mouse phenotypes are embryo and homeostasis/metabolism.

Wikipedia:68 Purpura fulminans (also known as \"Purpura gangrenosa\") is an acute, often fatal, thrombotic disorder... more...

Related Diseases for Purpura Fulminans

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Diseases in the Purpura Fulminans family:

Acquired Purpura Fulminans

Diseases related to Purpura Fulminans via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 194)
idRelated DiseaseScoreTop Affiliating Genes
1splenic abscess30.6F2, F3
2protein s deficiency29.4APOH, F2, F5, SERPINC1
3thrombophilia28.3F2, F3, F5, PROS1, SERPINC1
4acquired purpura fulminans12.3
5purpura11.1
6protein c deficiency11.0
7central nervous system osteosarcoma10.6F2, F3
8epiglottitis10.6F2, F3
9von willibrand disease, type 310.6F2, F3
10vaginal villous adenoma10.6F2, F3
11herpes gestationis10.6F2, F3
12acquired thrombocytopenia10.6F2, F3
13hypertrichosis10.6F2, F3
14skull base meningioma10.6F2, F3
15atypical hemolytic-uremic syndrome with h factor anomaly10.5SERPINA1, SERPINF2
16tricuspid valve disease10.5F2, F3
17vulvar melanoma10.4F3, SERPINA1
18microcytic anemia10.4F2, F3, PROS1
19meningococcemia10.3
20benign epilepsy with centrotemporal spikes10.3F3, F5
21disseminated intravascular coagulation10.3
22pneumonia10.3
23thrombophilia due to protein s deficiency, autosomal recessive10.3
24splenic infarction10.3F2, LACTB
25thrombophilia, x-linked, due to factor ix defect10.3F2, F3
26internuclear ophthalmoplegia10.3F2, F5
27microscopic colitis10.3F2, F5
28panniculitis10.3SERPINA1, SERPINF2
29dysthymic disorder10.3F2, F5
30meningitis10.3
31pontocerebellar hypoplasia10.3F2, F5
32diverticulitis of colon10.3F2, F5
33thumb absent short stature immune deficiency10.3APOH, F3
34moderately severe hemophilia a10.2F2, F5
35oral squamous cell carcinoma10.2F2, F5
36homocystinuria due to cbs deficiency10.2F2, F5
37chickenpox10.2
38mayer-rokitansky-kuster-hauser syndrome10.2APOH, F5
39meniere's disease10.2APOH, F2, F3
40tetanus10.2F3, F5
41irak4 deficiency10.2F2, F5
42pregnancy loss, recurrent 110.2APOH, F5
43thrombophilia due to protein c deficiency, autosomal recessive10.2
44malaria10.2
45burns10.2
46bubonic plague10.1APOH, F3, SERPINF2
47heterotopia, periventricular10.1F3, F5
48facioscapulohumeral muscular dystrophy 110.1F2, F3, F5
49thrombocytopenia cerebellar hypoplasia short stature10.1F2, F3, F5
50factor v deficiency10.0F2, F3, F5

Graphical network of the top 20 diseases related to Purpura Fulminans:



Diseases related to purpura fulminans

Symptoms for Purpura Fulminans

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UMLS symptoms related to Purpura Fulminans:


mucocutaneous haemorrhage, cullen's sign

Drugs & Therapeutics for Purpura Fulminans

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Drugs for Purpura Fulminans (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1AnticoagulantsPhase 2, Phase 31760
2Protein CPhase 2, Phase 386
3Fibrinolytic AgentsPhase 2, Phase 31567
4
HydrocortisoneapprovedPhase 258350-23-75754, 657311
Synonyms:
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
1 Hydrocortisone maximum strength
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
999 Itch Relieving
A-hydrocort
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Advanced Hydrocortisone
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti Itch
Anti Itch maximum strength
Anti Itch maximum strength plus
Anti-inflammatory hormone
Anti-itch
Anti-itch Scalp Relief Maximum Strength
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Apres Peel Soothing Balm
Aquacort
Aquanil HC
Atopalm Maximum Strength Anti-itch
Atopalm Moisturizing Hydrocortisone
Aveeno Hydrocortisone Anti Itch
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
Bioelements Immediate Comfort Hydrocortisone
Budpak Anti-itch
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Caldecort
Care One Hydrocortisone maximum strength
Cetacort
Chronocort
Cicatricure Ultra Moisturizing
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortaid 12-hour Advanced Anti-Itch
Cortaid Intensive Therapy Cooling
Cortaid Maximum Strength
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisone
Cortisone Cream Intensive Healing
Cortisone Maximum Strength
Cortisone maximum strength
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortizone 10
Cortizone 10 Cooling Cream Anti-itch
Cortizone 10 Cooling Relief
Cortizone 10 Easy Relief
Cortizone 10 Hydratensive Healing Anti Itch
Cortizone 10 Hydratensive Soothing Anti Itch
Cortizone 10 Intensive Healing
Cortizone 10 Intensive Healing Feminine Itch Relief
Cortizone 10 Intensive Healing For Eczema
Cortizone 10 Plus
Cortizone 10 Poison Ivy Relief Pads
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cvs Anti-itch Hydrocortisone
Cvs Cools Itch Fast
Cvs Cortisone
Cvs Pharmacy Anti-itch
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermacort Anti-Itch
Dermaquest Skin Therapy Post-skin Resurfacing Balm
Dermarest Eczema Medicated
Dermaspray
Dermil
Dermocortal
Dermolate
Dg Health Hydrocortisone
Dg Health Hydrocortisone Cream Maximum Strength
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Dr. Sheffield Hydrocortisone Anti Itch
Drotic
Duane Reade
Duane Reade hydrocortisone
Duane Reade hydrocortisone plus 12 moisturizers
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Equaline Anti Itch
Equaline Anti Itch maximum strength
Equate Hydrocortisone
Esiderm H
Evacort
Family Care Hydrocortisone
Family Wellness
Family Wellness Hydrocortisone
Family Wellness Maximum Strength Hydrocortisone
Ficortril
Fiocortril
Fixmyskin Healing Balm Fragrance-free
Fixmyskin Healing Balm Unflavored
Fixmyskin Healing Balm Vanilla Flavor
Fixmyskin Healing Balm Vanilla Fragrance
Flexicort
Foille Insetti
Formu Care Anti Itch maximum strength
Fulton Street Market Anti Itch
Genacort
Genacort (lotion)
Genuine Hydrocortisone
Glycort
Good Neighbor Pharmacy Anti Itch
Good Neighbor Pharmacy Hydrocortisone
Good Neighbor Pharmacy Hydrocortisone Plus 12 Moisturizers
Good Sense Anti Itch
Gyno-Cortisone
H 4001
H-Cort
H-releve Anti-itch
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Healerz For Itches
Health Mart Pharmacy Hydrocortisone Maximum Strength Plus 12 Moisturizers
Healthy Accents Cortisone maximum strength
Heb Cort
Heb-Cort
 
Hem-easy Relief Herbal Anti-itch Maximum Itch Relief
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro Skin
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone 1 plus 10
Hydrocortisone Acetate
Hydrocortisone Anti-itch Plus
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone D
Hydrocortisone HC
Hydrocortisone Intensive Healing Formula
Hydrocortisone Maximum Strength
Hydrocortisone Maximum Strength Plus 12 Moisturizers
Hydrocortisone Plus
Hydrocortisone Plus 12 Moisturizers
Hydrocortisone Probutate
Hydrocortisone Regular Strength
Hydrocortisone Sodium Phosphate
Hydrocortisone Ultra Strength
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone anti itch
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone maximum strength
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Intensive Healing Anti Itch
Kaiser Permanente Hydrocortisone
Kendall'S compound F
Kendall's compound F
Kera Hc Hydrocortisone
Kirkland Signature Hydrocortisone Plus maximum strength
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Leader Hydrocortisone
Locoid
Loesch Anti-Itch Therapy
Lopac0_000594
Lubricort
Lucky Supersoft MAXIMUM STRENGTH
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Makesense MAXIMUM STRENGTH
Maximum Strength Cortizone 10 Quick Shot 360 Continuous
Maximum Strength Hydrocortisone
Maximum-h
Medicort
Medpride
Meijer Anti Itch
Meijer Anti Itch Cream Plus
Meijer Hydrocortisone
Meijer Hydrocortisone Plus 12 Moisturizers
Members Mark Hydrocortisone
Meusicort
Mildison
Milliderm
MolPort-001-794-637
Monistat Complete Care Instant Itch Relief
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Natureplex Hydrocortisone Hydro
Neo-Cort-Dome
Neo-Cortef
Neosporin Eczema Essentials Anti Itch
Neosporin-H Ear
Nogenic HC
Nu-derm Tolereen Anti-pruritic
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pandel
Pediaderm Hc
Pediotic Suspension
Penecort
Permicort
Piyanping Antiitch
Polcort H
Premier Value Hydrocortisone
Premier Value Hydrocortisone Plus 12 Moisturizers
Preparation H Hydrocortisone
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proactiv Solution Anti-itch Scalp
Procto-pak
Proctocort
Proctocream HC
Proctofoam
Proctosol-hc
Proctozone HC
Procure
Protocort
Publix Hydro
Publix hydro plus
Quadrydern
Quality Choice Hydrocortisone
Quality Choice Hydrocortisone Maximum Strength
Quality Choice Maximum Strength Anti Itch
Racet
Rectasol-HC
Rectoid
Refuge Hc
Reichstein'S substance M
Reichstein's substance M
Remederm HC
Rexall Anti Itch maximum strength relief
Rexall Hydrocortisone 1
Rexall Hydrocortisone plus moisturizers
Rite Aid anti-itch
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Safeway Hydrocortisone Plus 12 Moisturizers
Sanatison
Scalp-Cort
Scalpicin Anti-Itch Maximum Strength
Scalpicin Capilar
Scalpicin Maximum Strength
Scalpicin Scalp Itch Medication Maximum Strength
Schericur
Scheroson F
Shopko Hydrocortisone
Shopko Hydrocortisone Intensive Healing Formula
Shopko Hydrocortisone Maximum Strength
Shopko Hydrocortisone Plus 12 Moisturizers Maximum Strength
Shopko Maximum Strength
Shoprite Hydrocortisone
Sigmacort
Signef
Smart Sense Anti Itch
Smart Sense Anti Itch maximum strength
Smart Sense Hydrocortisone
Solu-cortef
Soothe Rodan Fields
Stie-cort
Stiefcorcil
Sunmark Hydrocortisone
Sunmark Hydrocortisone Plus 12 Moisturizers
Synacort
Systral Hydrocort
Tarcortin
Tecnu Corticool
Texacort
Texacort lotion 25
Thera Plus
Timocort
Topcare Hydrocortisone
Topcare Hydrocortisone Intensive Healing Formula
Topcare Hydrocortisone Plus 12 Moisturizers
Topicort
Transderma H
Traumaide
Truelipids Anti-itch Barrier
U-cort
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Walgreens Hydrocortisone Plus 12 Moisturizers
Westcort
Western Family HydroCortisone
Western Family HydroCortisone Plus 12 Moisturizers
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
5
butyric acidexperimentalPhase 2292107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
 
Butyric acid
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid
6Hydrocortisone acetatePhase 2583
7Hydrocortisone-17-butyratePhase 2583
8Hydrocortisone 17-butyrate 21-propionatePhase 2583
9Cortisol succinatePhase 2583
10Anti-Inflammatory AgentsPhase 28478
11Dermatologic AgentsPhase 24555

Interventional clinical trials:

idNameStatusNCT IDPhase
1Efficacy and Safety Study of Protein C Concentrate in Subjects With Severe Congenital Protein C DeficiencyCompletedNCT00157118Phase 2, Phase 3
2Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot StudyCompletedNCT00732277Phase 2
3Sepsis-Associated Purpura Fulminans International Registry - EuropeNot yet recruitingNCT02238795

Search NIH Clinical Center for Purpura Fulminans


Cochrane evidence based reviews: purpura fulminans

Genetic Tests for Purpura Fulminans

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Anatomical Context for Purpura Fulminans

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MalaCards organs/tissues related to Purpura Fulminans:

33
Skin, Breast, Liver, Colon, Lung, Thyroid, Prostate

Animal Models for Purpura Fulminans or affiliated genes

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MGI Mouse Phenotypes related to Purpura Fulminans:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053808.4F2, F3, F5, PROCR, PROS1, SERPINC1
2MP:00053766.5APOH, F2, F3, F5, PROC, PROCR

Publications for Purpura Fulminans

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Articles related to Purpura Fulminans:

(show top 50)    (show all 410)
idTitleAuthorsYear
1
Streptococcus pneumoniae-induced purpura fulminans. (27083982)
2016
2
Angioimmunoblastic t-cell lymphoma presenting as purpura fulminans. (25750965)
2015
3
Infectious purpura fulminans. (25857509)
2015
4
Pravastatin-induced rhabdomyolysis and purpura fulminans in a patient with chronic renal failure. (25644555)
2015
5
A novel mutation c.1048A>T at codon 350(Lys>Stop) in PROC gene causing neonatal purpura fulminans. (24158118)
2013
6
Idiopathic purpura fulminans. (20674230)
2011
7
Diagnosis and management of neonatal purpura fulminans. (21839696)
2011
8
Purpura fulminans: recognition, diagnosis and management. (21233082)
2011
9
Human skin allografts as a useful adjunct in the treatment of purpura fulminans. (20852508)
2010
10
Purpura fulminans in a patient with rheumatoid arthritis. (19997707)
2009
11
Varicella-associated purpura fulminans and multiple deep vein thromboses: a case report. (19602824)
2009
12
Hypothesis: is the skin and tissue loss associated with septic purpura fulminans temperature related? Parallels with the anatomical distribution of frostbite. (18221840)
2008
13
Capnocytophaga ochracea causing severe sepsis and purpura fulminans in an immunocompetent patient. (16882454)
2007
14
Hereditary angioedema associated with heterozygous factor V Leiden mutation in a patient with Purpura fulminans. (17068406)
2007
15
Purpura fulminans: an unusual manifestation of severe falciparum malaria. (17588627)
2007
16
Suitable age for nasal reconstruction after subtotal amputation in a child, with respect to a case involving purpura fulminans. (16952604)
2006
17
Purpura fulminans during meningococcal sepsis treated with Drotrecogin alpha. A clinical case. (16570037)
2006
18
Purpura fulminans secondary to transient protein C deficiency as a complication of chickenpox infection. (16918648)
2006
19
Massive soft tissue infections: necrotizing fasciitis and purpura fulminans. (15715517)
2005
20
Adult purpura fulminans associated with staphylococcal infection and administration of colony-stimulating factors. (12609794)
2003
21
Homozygous protein C deficiency with purpura fulminans: report of a new case and a description of a novel mutation. (12695756)
2003
22
An open-label study of the role of adjuvant hemostatic support with protein C replacement therapy in purpura fulminans-associated meningococcemia. (11090052)
2000
23
Postinfection purpura fulminans in a patient heterozygous for prothrombin G20210A and acquired protein S resistance. (10599098)
1999
24
Reconstructive surgery in children after meningococcal purpura fulminans. (10235331)
1999
25
Protein-C concentrate for meningococcal purpura fulminans. (9734967)
1998
26
Acute infectious purpura fulminans: pathogenesis and medical management. (9655311)
1998
27
Use of protein-C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans. (9393338)
1997
28
Neonatal purpura fulminans in association with factor V R506Q mutation. (8627449)
1996
29
Management strategy in purpura fulminans with multiple organ failure in children. (8719318)
1996
30
Treatment of purpura fulminans in meningococcemia with protein C concentrate. (7699550)
1995
31
Meningococcal purpura fulminans treated with antithrombin III concentrate: what is the optimal replacement therapy? (7848164)
1994
32
Epidural sympathetic blockade to relieve vascular insufficiency in an infant with purpura fulminans. (8375170)
1993
33
Epidemic meningococcemia and purpura fulminans with induced protein C deficiency. (8399877)
1993
34
Purpura fulminans due to protein S deficiency following chickenpox. (1386247)
1992
35
Streptococcal gangrene and purpura fulminans. (1298264)
1992
36
Successful treatment of neonatal purpura fulminans with epoprostenol. (1744852)
1991
37
Purpura fulminans and adrenal hemorrhage due to group Y meningococcemia in an elderly woman. (1901668)
1991
38
Treatment of homozygous protein C deficiency and neonatal purpura fulminans with a purified protein C concentrate. (1944440)
1991
39
More questions about purpura fulminans. (2297246)
1990
40
Anticoagulant combination therapy of gabexate mesilate and urokinase in purpura fulminans. (3144146)
1987
41
Purpura fulminans following late-onset group B beta-hemolytic streptococcal sepsis. (6383017)
1984
42
Amputation following meningococcemia. A sequela to purpura fulminans. (6705382)
1984
43
Purpura fulminans. (6461269)
1982
44
Dilantin-induced disseminated intravascular coagulation with purpura fulminans. A case report. (1147459)
1975
45
Fatal purpura fulminans following total cardiopulmonary bypass. (4767451)
1973
46
Purpura fulminans. (4936527)
1971
47
Purpura fulminans treated with hyperbaric oxygen. (5475825)
1970
48
Microangiopathic hemolytic anemia caused by purpura fulminans. (5653626)
1968
49
Purpura fulminans associated with septicaemia. (6080580)
1967
50
PURPURA FULMINANS FOLLOWING A MILD CASE OF SCARLET FEVER. (20774576)
1929

Variations for Purpura Fulminans

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Expression for genes affiliated with Purpura Fulminans

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Search GEO for disease gene expression data for Purpura Fulminans.

Pathways for genes affiliated with Purpura Fulminans

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Pathways related to Purpura Fulminans according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Warfarin Pathway, Pharmacodynamics53
9.4F2, PROC, PROS1
2
Gamma carboxylation, hypusine formation and arylsulfatase activation57
Show member pathways
9.4F2, PROC, PROS1
3
Cell surface interactions at the vascular wall57
Show member pathways
9.0F2, PROC, PROCR, PROS1
4
Collagen biosynthesis and modifying enzymes57
Show member pathways
8.3F2, F3, F5, PROC, PROS1, SERPINC1
5
Formation of Fibrin Clot (Clotting Cascade)57
Show member pathways
7.4F2, F3, F5, PROC, PROCR, PROS1
6
Complement and coagulation cascades31 39
Show member pathways
6.8F2, F3, F5, PROC, PROCR, PROS1
7
Platelet activation, signaling and aggregation57
Show member pathways
6.0APOH, F2, F3, F5, PROC, PROCR

GO Terms for genes affiliated with Purpura Fulminans

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Cellular components related to Purpura Fulminans according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:003109310.1F5, SERPINA1
2endoplasmic reticulum lumenGO:00057889.4F5, PROC, SERPINA1
3extracellular regionGO:00055768.4F5, PROC, PROS1, SERPINA1, SERPINC1

Biological processes related to Purpura Fulminans according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of collagen biosynthetic processGO:003296710.0F2, SERPINF2
2peptidyl-glutamic acid carboxylationGO:00171879.9F2, PROC, PROS1
3acute-phase responseGO:00069539.8SERPINA1, SERPINF2
4negative regulation of blood coagulationGO:00301959.8APOH, PROC
5regulation of blood coagulationGO:00301939.8APOH, F2
6platelet degranulationGO:00025768.9APOH, PROS1, SERPINF2
7post-translational protein modificationGO:00436878.9F5, PROC, PROS1, SERPINA1
8cellular protein metabolic processGO:00442678.8F2, F5, PROS1, SERPINA1
9negative regulation of endopeptidase activityGO:00109518.8PROS1, SERPINA1, SERPINC1, SERPINF2
10blood coagulationGO:00075968.5F2, F5, PROC, SERPINA1, SERPINF2

Sources for Purpura Fulminans

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z