Aliases & Classifications for Pyelonephritis

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 38NCIt, 55SNOMED-CT, 33MeSH, 27ICD9CM
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Pyelonephritis, Aliases & Descriptions:

Name: Pyelonephritis 9 11 43 60


External Ids:

Disease Ontology9 DOID:11400
NCIt38 C34965
MeSH33 D011704
ICD9CM27 590.80

Summaries for Pyelonephritis

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Wikipedia:63 Pyelonephritis /pa??lo?n??fra?t?s/ (from Greek ?????|? p more...

MalaCards based summary: Pyelonephritis is related to acute pyelonephritis and chronic pyelonephritis. An important gene associated with Pyelonephritis is NAGLU (N-acetylglucosaminidase, alpha), and among its related pathways are Selenium Pathway and Selected targets of HNF1. The compounds amikacin and tobramycin have been mentioned in the context of this disorder. Affiliated tissues include kidney, testes and liver, and related mouse phenotypes are immune system and renal/urinary system.

Related Diseases for Pyelonephritis

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Diseases in the Pyelonephritis family:

Acute Pyelonephritis Chronic Pyelonephritis

Diseases related to Pyelonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 207)
idRelated DiseaseScoreTop Affiliating Genes
1acute pyelonephritis32.1NAGLU, CXCR1, CRP
2chronic pyelonephritis31.8B2M, NAGLU, UMOD
3cystitis31.3UMOD, NAGLU
4vesicoureteral reflux31.1UMOD, NAGLU
5bacteriuria31.1CRP, UMOD
6nephrolithiasis30.8NAGLU, UMOD
7nephritis30.5ALB, B2M
8amyloidosis30.2B2M, ALB, CRP
9tuberculosis30.2CXCR1, ALB, CRP
10glomerulonephritis30.2B2M, NAGLU, UMOD, ALB
11nephrotic syndrome30.1ALB, NAGLU, B2M
12lupus nephritis29.9ALB, NAGLU
13urinary tract obstruction29.9B2M, NAGLU, UMOD
14hyperhomocysteinemia29.8ALB, CRP
15crohn's disease29.8ALB, CRP
16hyperparathyroidism29.8ALB, CALCA
17rheumatoid arthritis29.8CRP, CXCR1, NAGLU, B2M
18acute kidney failure29.6B2M, NAGLU, UMOD, ALB
19uremia29.5CRP, ALB, B2M
20proteinuria29.5B2M, NAGLU, UMOD, ALB, CRP
21hypercalcemia29.5ALB, CALCA, B2M
22pancreatitis29.4CRP, ALB
23myeloma29.4B2M, NAGLU, UMOD, ALB
24arthritis29.3B2M, CXCR1, CALCA, ALB, CRP
25chronic kidney failure29.1B2M, NAGLU, UMOD, ALB, CRP
26breast cancer29.0NAGLU, CXCR1, CALCA, ALB
27xanthogranulomatous pyelonephritis11.2
28renal cell carcinoma10.4
29hydronephrosis10.4
30pyelitis10.4
31bacteremia10.4
32hepatitis10.4
33osteitis fibrosa10.4B2M
34acute kidney tubular necrosis10.3UMOD, NAGLU
35interstitial nephritis10.3
36urethritis10.3
37nephrocalcinosis10.3UMOD, NAGLU
38hepatorenal syndrome10.3ALB
39blindness10.3
40pseudohypoparathyroidism10.3CALCA, NAGLU
41hypoparathyroidism10.3NAGLU, CALCA
42pseudohypoaldosteronism10.2
43perinephritis10.2
44lipomatosis10.2
45horseshoe kidney10.2
46urinary system disease10.2NAGLU, B2M
47malignant hypertension10.2
48prostatitis10.2
49malakoplakia10.2
50viral meningitis10.2CRP, B2M

Graphical network of the top 20 diseases related to Pyelonephritis:



Diseases related to pyelonephritis

Symptoms for Pyelonephritis

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Drugs & Therapeutics for Pyelonephritis

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Drug clinical trials:

Search ClinicalTrials for Pyelonephritis

Search NIH Clinical Center for Pyelonephritis

Genetic Tests for Pyelonephritis

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Anatomical Context for Pyelonephritis

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MalaCards organs/tissues related to Pyelonephritis:

31
Kidney, Testes, Liver, Colon, Prostate, Neutrophil, Cortex, Spinal cord, Bone, Lung, Whole blood, Lymph node, Spleen, Brain, Heart, Thyroid, Breast, Ovary, Monocytes, T cells, B cells, Endothelial

Animal Models for Pyelonephritis or affiliated genes

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MGI Mouse Phenotypes related to Pyelonephritis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.2CRP, UMOD, NAGLU, CPN1, B2M
2MP:00053678.1ALB, CALCA, UMOD, NAGLU

Publications for Pyelonephritis

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Articles related to Pyelonephritis:

(show top 50)    (show all 1598)
idTitleAuthorsYear
1
Oral penicillin-associated acute kidney injury in an infant with acute pyelonephritis. (25711153)
2015
2
The efficacy of non-carbapenem antibiotics for the treatment of community-onset acute pyelonephritis due to extended-spectrum I^-lactamase-producing Escherichia coli. (24928854)
2014
3
Xanthogranulomatous pyelonephritis: the case of a perplexing kidney. (25240002)
2014
4
Emphysematous pyelonephritis and cystitis in a renal transplant recipient. (25320257)
2014
5
Are serum procalcitonin and interleukin-1 beta suitable markers for diagnosis of acute pyelonephritis in children? (24874931)
2014
6
Emphysematous Pyelonephritis-a Rare Surgical Emergency Presenting to the Physician: A Case Report and Literature Review. (24426588)
2013
7
Urinary concentration of cytokines in children with acute pyelonephritis. (23389820)
2013
8
Mouse model for pyelonephritis. (23564687)
2013
9
The effects of anemia on pregnancy outcome in patients with pyelonephritis. (24369448)
2013
10
Pyelonephritis in pregnancy. How adequate is empirical treatment? (23546459)
2013
11
The effect of vitamin E or vitamin A on the prevention of renal scarring in children with acute pyelonephritis. (23052650)
2013
12
Genotypic Analysis of E. coli Strains Isolated from Patients with Cystitis and Pyelonephritis. (22997556)
2012
13
The influence of chronic renal failure on the spectrum and antimicrobial susceptibility of uropathogens in community-acquired acute pyelonephritis presenting as a positive urine culture. (21507269)
2011
14
Selection of first-line i.v. antibiotics for acute pyelonephritis in patients requiring emergency hospital admission. (20839025)
2011
15
Five patients with emphysematous pyelonephritis. (21525582)
2011
16
Emphysematous pyelonephritis and pneumo-vena cava. (21293779)
2010
17
Pharmacotherapy of lower urinary tract infections and pyelonephritis in children. (19663608)
2009
18
A rare association of emphysematous pyelonephritis with unrecognized diabetes and polycystic kidney. (20352007)
2009
19
Pyelonephritis during pregnancy: a cause for an acquired deficiency of protein Z. (18828054)
2008
20
A case of portal venous gas after extracorporeal shockwave lithotripsy and obstructive pyelonephritis. (18342210)
2008
21
Antibiotics for acute pyelonephritis in children. (17943796)
2007
22
Emphysematous pyelonephritis in a diabetic patient with pelvic-ureteric stone. (18705456)
2007
23
Some current aspects of diagnosis of calculous pyelonephritis]. (17471991)
2007
24
Renal parenchymal malacoplakia: a different stage of xanthogranulomatous pyelonephritis? (17618870)
2007
25
Association between mannose-binding lectin deficiency and septic shock following acute pyelonephritis due to Escherichia coli. (17202308)
2007
26
Oestroprogestagens and severe acute pyelonephritis: a casual or causal association? (16868038)
2006
27
Clarithromycin: immunomodulatory therapy of experimental sepsis and acute pyelonephritis by Escherichia coli. (15764190)
2005
28
Correlational studies of urine interleukin 6, interleukin 8 and nitric oxide in the patients with pyelonephritis and hydronephrosis]. (16308433)
2005
29
Successful medical treatment of emphysematous pyelonephritis. (17914710)
2004
30
Procalcitonin in pyelonephritis and acute community-acquired pneumonia in adults]. (11484399)
2001
31
Xanthogranulomatous pyelonephritis: urinary and fine needle aspiration cytology. (9684612)
1998
32
Focal xanthogranulomatous pyelonephritis in a teenager. (9717648)
1998
33
Effect of chronic renal hemodialysis on serum total, free and acyl carnitine concentrations in adult chronic pyelonephritis patients. (9078596)
1997
34
Xanthogranulomatous pyelonephritis in pediatric patients. (7752369)
1995
35
Renin-angiotensin-aldosterone system in peripheral blood and concentration of albumin and beta2 microglobulin in urine of women with chronic glomerulonephritis and chronic pyelonephritis]. (7817590)
1994
36
Sexual acquisition of acute pyelonephritis in a man. (8460339)
1993
37
Diagnosis of acute pyelonephritis in children: comparison of sonography and 99mTc-DMSA scintigraphy. (1651644)
1991
38
Acute pyelonephritis in pregnancy at Ramathibodi Hospital: a descriptive epidemiological study. (3183551)
1988
39
Generalized amyloidosis secondary to xanthogranulomatous pyelonephritis. (3816863)
1986
40
Acute pyelonephritis in pregnancy. (3791931)
1986
41
Xanthogranulomatous pyelonephritis in children. (3968740)
1985
42
Urinary tract infection during pregnancy. Asymptomatic bacteriuria, acute cystitis, and acute pyelonephritis. (6374641)
1984
43
Xanthogranulomatous pyelonephritis with bilharzial ureteric obstruction. (6653472)
1983
44
Effect of water diuresis on chronic pyelonephritis. (5659542)
1968
45
Chronic pyelonephritis: relative incidence in transplant recipients. (5330923)
1966
46
CHRONIC PYELONEPHRITIS AND THE ANTIBIOTICS. (14062883)
1963
47
XANTHOGRANULOMATOUS PYELONEPHRITIS. (14134284)
1963
48
Chronic pyelonephritis with xanthogranulomatous change; report of 3 cases. (13248828)
1955
49
CLINICAL pathologic conference: acute and subacute glomerulonephritis with acute pyelonephritis. (13061782)
1953
50
Clinico-pathological conference: hypoplasia of the kidneys secondary to chronic pyelonephritis; acute bronchitis; myocardial hypertrophy; fatty metamorphosis of the liver; rickets. (14870327)
1951

Variations for Pyelonephritis

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Expression for genes affiliated with Pyelonephritis

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Search GEO for disease gene expression data for Pyelonephritis.

Pathways for genes affiliated with Pyelonephritis

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Pathways related to Pyelonephritis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
thioredoxin pathway36
9.2CRP, ALB

Compounds for genes affiliated with Pyelonephritis

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Compounds related to Pyelonephritis according to GeneCards Suite gene sharing:

(show top 50)    (show all 103)
idCompoundScoreTop Affiliating Genes
1amikacin439.8B2M, NAGLU
2tobramycin439.8NAGLU, B2M
3fosfomycin439.8NAGLU, B2M
4calcium oxalate439.8UMOD, NAGLU
5aluminium43 1210.7B2M, NAGLU
6mesna439.7B2M, NAGLU
799mtc-dmsa439.5B2M, NAGLU, CRP
8polyether sulfone439.4ALB, B2M
9neopterin439.4NAGLU, B2M, CRP
10fluoride439.3CALCA, B2M, NAGLU
11aopp439.3CRP, ALB
1251-cr-edta439.3B2M, ALB
13pamidronate43 49 1211.3CALCA, CRP, B2M
14pmma439.3CRP, CALCA, B2M
15perindopril43 49 1211.3NAGLU, CRP, ALB
16nitroglycerin43 1210.2B2M, CALCA, CRP
17isoflurane49 43 1211.2NAGLU, ALB, CALCA
18furosemide43 59 28 49 24 1214.2ALB, CALCA, NAGLU
19icodextrin43 1210.1B2M, ALB
20losartan43 49 28 1212.1CRP, ALB, NAGLU
21iopentol439.1ALB, NAGLU, B2M
22p-aminohippuric acid439.1ALB, NAGLU, B2M
23inulin439.1B2M, NAGLU, ALB
24iohexol439.1ALB, B2M, NAGLU
25fosinopril43 1210.1ALB, CRP
26sevoflurane49 43 1211.1B2M, ALB, NAGLU
27calcium carbonate439.0CALCA, B2M
28gamma globulin439.0ALB, CRP, B2M
29pentosidine439.0B2M, ALB, CRP
30dmsa439.0CRP, NAGLU, B2M, CALCA
31polysulfone439.0CRP, B2M, ALB
32vitamin b12438.9ALB, B2M, CRP
33citrate438.9ALB, CRP, UMOD, NAGLU
34captopril43 59 49 28 1212.9B2M, CALCA, ALB
35homocysteine43 249.9NAGLU, ALB, CRP
36urea43 24 1210.7ALB, NAGLU, B2M, UMOD
37mannitol43 129.6ALB, CRP, NAGLU, B2M
38vitamin a43 24 1210.6NAGLU, ALB, CRP, B2M
39phosphorus438.6ALB, CALCA, NAGLU, B2M
40vitamin d438.5NAGLU, ALB, CALCA, B2M
4125-hydroxyvitamin d438.5CRP, ALB, B2M, CALCA
42sodium43 249.5ALB, NAGLU, B2M, UMOD
43iron43 249.5NAGLU, CRP, ALB, B2M
44uric acid43 249.3NAGLU, B2M, ALB, UMOD, CRP
45aspartate438.3CRP, ALB, NAGLU, B2M
46cysteine438.2NAGLU, CXCR1, ALB, UMOD, B2M
47glucose438.2CRP, ALB, UMOD, B2M, NAGLU
48lactate438.1CRP, ALB, CALCA, NAGLU, B2M
49creatinine437.8ALB, CALCA, UMOD, NAGLU, B2M, CRP
50calcium43 49 24 1210.3ALB, CALCA, UMOD, CXCR1, CRP, NAGLU

GO Terms for genes affiliated with Pyelonephritis

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Cellular components related to Pyelonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular vesicular exosomeGO:00700628.3ALB, UMOD, NAGLU, B2M
2extracellular regionGO:00055767.8B2M, CALCA, ALB, CRP
3extracellular spaceGO:00056157.1CRP, ALB, CALCA, UMOD, CPN1, B2M

Biological processes related to Pyelonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor internalizationGO:00316239.4CALCA, CXCR1
2response to organic substanceGO:00100339.3ALB, UMOD
3inflammatory responseGO:00069549.1CRP, CALCA, CXCR1
4retina homeostasisGO:00018958.7ALB, B2M

Products for genes affiliated with Pyelonephritis

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Sources for Pyelonephritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet