Aliases & Classifications for Pyloric Stenosis

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 56SNOMED-CT, 39NCIt, 33MeSH, 61UMLS
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Aliases & Descriptions for Pyloric Stenosis:

Name: Pyloric Stenosis 8 10 44


External Ids:

Disease Ontology8 DOID:12639
NCIt39 C34966
SNOMED-CT56 367403001
MeSH33 D011707

Summaries for Pyloric Stenosis

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Wikipedia:64 Pyloric stenosis or pylorostenosis is narrowing (stenosis) of the opening from the stomach to the first... more...

MalaCards based summary: Pyloric Stenosis is related to hypertrophic pyloric stenosis and pylorospasm. An important gene associated with Pyloric Stenosis is NOS1 (nitric oxide synthase 1 (neuronal)), and among its related pathways are Metabolism of porphyrins and PEDF Induced Signaling. The compounds zinc protoporphyrin and mptp have been mentioned in the context of this disorder. Affiliated tissues include small intestine, pancreas and breast, and related mouse phenotypes are respiratory system and digestive/alimentary.

Related Diseases for Pyloric Stenosis

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Diseases related to Pyloric Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 164)
idRelated DiseaseScoreTop Affiliating Genes
1hypertrophic pyloric stenosis11.4
2pylorospasm10.6
3esophagitis10.5
4neuronitis10.5
5eosinophilic gastroenteritis10.5
6duodenitis10.5
7gastroenteritis10.5
8acquired gastric outlet stenosis10.4
9atrioventricular block10.4NKX2-5
10hirschsprung disease 110.4GDNF
11pyloric stenosis, infantile hypertrophic, 310.4
12pyloric stenosis, infantile hypertrophic, 210.4
13pyloric stenosis, infantile hypertrophic, 510.4
14marden-walker syndrome10.4
15pyloric stenosis, infantile hypertrophic, 410.4
16crohn's disease10.4
17esophageal atresia10.4
18gastric outlet obstruction10.4
19glomus tumor10.3DES
20smith-lemli-opitz syndrome10.3
21jacobsen syndrome10.3
22ulnar-mammary syndrome10.3
23koolen-de vries syndrome10.3
24intestinal pseudoobstruction, neuronal10.3
25epidermolysis bullosa, junctional, with pyloric stenosis10.3
26gilbert syndrome10.3
27gastric dilatation10.3
28pneumatosis cystoides intestinalis10.3
29epidermolysis bullosa10.3
30pertussis10.3
31tracheoesophageal fistula10.3
32intellectual disability-hypotonia-brachycephaly-pyloric stenosis-cryptorchidism syndrome10.3
33neonatal jaundice10.3UGT1A1
34epidermolysis bullosa, junctional, non-herlitz type10.2
35kleefstra syndrome10.2
36gastroesophageal reflux10.2
37renal cysts and diabetes syndrome10.2
38arterial tortuosity syndrome10.2
39ornithine transcarbamylase deficiency10.2
40hypoparathyroidism, sensorineural deafness, and renal dysplasia10.2
41heterotopia, periventricular, ed variant10.2
42chronic granulomatous disease10.2
43duodenal ulcer10.2
44gastric ulcer10.2
45cornelia de lange syndrome10.2
46epidermolysis bullosa simplex10.2
47junctional epidermolysis bullosa10.2
48achalasia10.2
49congenital diaphragmatic hernia10.2
50gastritis10.2

Graphical network of the top 20 diseases related to Pyloric Stenosis:



Diseases related to pyloric stenosis

Symptoms for Pyloric Stenosis

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Drugs & Therapeutics for Pyloric Stenosis

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Drug clinical trials:

Search ClinicalTrials for Pyloric Stenosis

Search NIH Clinical Center for Pyloric Stenosis

Genetic Tests for Pyloric Stenosis

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Anatomical Context for Pyloric Stenosis

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MalaCards organs/tissues related to Pyloric Stenosis:

31
Small intestine, Pancreas, Breast, Smooth muscle, Kidney, Brain, Heart, Liver, Lung, Skin, Ovary, Testes, Endothelial

Animal Models for Pyloric Stenosis or affiliated genes

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MGI Mouse Phenotypes related to Pyloric Stenosis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.6NOS1, HMOX2, NKX2-5, NGFR
2MP:00053818.4GDNF, NGFR, HMOX2, NOS1
3MP:00053768.1NOS1, HMOX2, NKX2-5, NGFR, DES
4MP:00053868.0GDNF, DES, NGFR, HMOX2, NOS1
5MP:00036317.8GDNF, NGFR, NKX2-5, HMOX2, NOS1
6MP:00053697.7NOS1, HMOX2, NKX2-5, NGFR, DES, GDNF
7MP:00053857.7GDNF, DES, NGFR, NKX2-5, HMOX2, NOS1
8MP:00107687.7GDNF, DES, NGFR, NKX2-5, HMOX2, NOS1

Publications for Pyloric Stenosis

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Articles related to Pyloric Stenosis:

(show top 50)    (show all 733)
idTitleAuthorsYear
1
Infantile hypertrophic pyloric stenosis: has anything changed? (23198903)
2013
2
Role of bottle feeding in the etiology of hypertrophic pyloric stenosis. (24146084)
2013
3
Images in clinical medicine. Peristaltic waves in pyloric stenosis. (24088114)
2013
4
Development of pyloric stenosis after a 4-day course of oral erythromycin. (23558266)
2013
5
Alkalosis-induced respiratory depression from infantile hypertrophic pyloric stenosis. (21293220)
2011
6
The role of RET genomic variants in infantile hypertrophic pyloric stenosis. (22169991)
2011
7
Esophageal atresia/tracheoesophageal fistula complicated by hypertrophic pyloric stenosis: a case report. (20113643)
2010
8
Pylorospasm (simulating hypertrophic pyloric stenosis) with secondary gastroesophageal reflux. (18528245)
2008
9
Previously unsuspected infantile hypertrophic pyloric stenosis diagnosed by endoscopy. (17934821)
2008
10
Ultrasonographic serial measurements of the morphologic resolution of the pylorus after Ramstedt pyloromyotomy for infantile hypertrophic pyloric stenosis. (18029919)
2007
11
Proton pump inhibition is a feasible primary alternative to surgery and balloon dilatation in adult peptic pyloric stenosis (APS): report of six consecutive cases. (16551413)
2006
12
Familial pyloric stenosis associated with developmental delays. (15990644)
2005
13
Pyloric stenosis and neuronal nitric oxide synthase]. (15361336)
2004
14
Very early exposure to erythromycin and infantile hypertrophic pyloric stenosis. (12090829)
2002
15
Junctional epidermolysis bullosa with pyloric stenosis. (11841649)
2001
16
Maternal and infant use of erythromycin and other macrolide antibiotics as risk factors for infantile hypertrophic pyloric stenosis. (11562617)
2001
17
Absence of Epstein-Barr virus in smooth muscle cells of idiopathic hypertrophic pyloric stenosis. (11231484)
2001
18
In vivo visualization of pyloric mucosal hypertrophy in infants with hypertrophic pyloric stenosis: is there an etiologic role? (11566686)
2001
19
Ectopic pancreas: a rare cause of pyloric stenosis. (10862516)
2000
20
Infantile hypertrophic pyloric stenosis in a 5-month-old baby: case report. (10974761)
2000
21
Erythromycin use linked to pyloric stenosis. (10738394)
2000
22
Infantile hypertrophic pyloric stenosis after pertussis prophylaxis with erythromcyin: a case review and cohort study. (10609814)
1999
23
Pyloric muscle in asymptomatic infants: sonographic evaluation and discrimination from idiopathic hypertrophic pyloric stenosis. (9634457)
1998
24
Ultrasonographic follow-up of the healing process of medically treated hypertrophic pyloric stenosis. (9561540)
1998
25
Ultrasonography of pylorospasm: findings may simulate hypertrophic pyloric stenosis. (9805307)
1998
26
Endoscopic hydrostatic balloon dilation of ulcer-induced pyloric stenosis in rheumatoid arthritis and secondary amyloidosis. (9171133)
1997
27
Altered messenger RNA expression of the neuronal nitric oxide synthase gene in infantile hypertrophic pyloric stenosis. (9354728)
1997
28
Congenital pyloric stenosis: a modified umbilical incision for pyloromyotomy (9069247)
1997
29
Laparoscopic truncal vagotomy and gastroenterostomy for pyloric stenosis. (8678208)
1996
30
Early infantile hypertrophic pyloric stenosis: surgery at 26 hours of age. (8877358)
1996
31
Transient neonatal myasthenia gravis and pyloric stenosis. (8534471)
1995
32
Benign pyloric stenosis in an intrathoracic stomach. (7656368)
1995
33
The ultrasonic diagnosis of infantile hypertrophic pyloric stenosis: technique and accuracy. (8162680)
1994
34
An analysis of feeding regimens after pyloromyotomy for hypertrophic pyloric stenosis. (8301463)
1993
35
Infantile hypertrophic pyloric stenosis: myopathic type. (2169173)
1990
36
Multinodular adult hypertrophic pyloric stenosis. (2584668)
1989
37
Does earlier admission in infantile hypertrophic pyloric stenosis (IHPS) apparently increase incidence rates? (3335980)
1988
38
Re: Infantile hypertrophic pyloric stenosis. (3744758)
1986
39
Infantile hypertrophic pyloric stenosis: a review of 222 cases. (3460546)
1986
40
300 infants with hypertrophic pyloric stenosis: presentation and outcome. (3721820)
1986
41
The role of prostaglandins E2 and F2 alpha in infantile hypertrophic pyloric stenosis. (3458896)
1986
42
Report of two patients with hypertrophic pyloric stenosis and Hirschsprung's disease. Coincident or common etiology? (4026078)
1985
43
Muscle thickness in hypertrophic pyloric stenosis: sonographic determination. (6600332)
1983
44
Infantile hypertrophic pyloric stenosis--congenital or acquired? (7077061)
1982
45
Infantile hypertrophic pyloric stenosis -- a rarity in Malaysia? (7167088)
1982
46
X-linked ichthyosis associated with hypertrophic pyloric stenosis in three brothers. (7196302)
1981
47
The effect of pyloromyotomy on serum and luminal gastrin in infants with hypertrophic pyloric stenosis. (7421172)
1980
48
Idiopathic hypertrophic pyloric stenosis in adults. (7401003)
1980
49
Late presentation of hypertrophic pyloric stenosis. (470691)
1979
50
Extraordinary hyperbilirubinemia in a neonate with idiopathic hypertrophic pyloric stenosis. (117092)
1979

Variations for Pyloric Stenosis

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Expression for genes affiliated with Pyloric Stenosis

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Search GEO for disease gene expression data for Pyloric Stenosis.

Pathways for genes affiliated with Pyloric Stenosis

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Pathways related to Pyloric Stenosis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
tetrapyrrole biosynthesis36
heme degradation36
Heme Biosynthesis36
heme biosynthesis36
heme biosynthesis from uroporphyrinogen-III I36
9.2HMOX2, UGT1A1
2
Show member pathways
9.0NOS1, NGFR, GDNF
39.0NOS1, NGFR, GDNF

Compounds for genes affiliated with Pyloric Stenosis

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Compounds related to Pyloric Stenosis according to GeneCards Suite gene sharing:

(show all 49)
idCompoundScoreTop Affiliating Genes
1zinc protoporphyrin4410.1HMOX2, NOS1
2mptp449.9NOS1, GDNF
3capsaicin44 2810.9NOS1, GDNF
4peroxynitrite449.7NGFR, NOS1
5guanylate449.6HMOX2, NOS1
6hematoxylin449.6DES, NGFR
7imipramine44 28 50 24 1113.6UGT1A1, NOS1
8dbc-amp449.5NGFR, GDNF
9norepinephrine44 24 1111.4NOS1, GDNF, DES
10choline44 24 1111.4GDNF, NGFR, NOS1
11creatinine449.4NOS1, GDNF, DES
12nadph44 2410.4NGFR, HMOX2, NOS1
13gaba449.4NGFR, NOS1, GDNF
14hydroxyurea44 50 1111.3UGT1A1, NOS1
15actinomycin d449.3DES, GDNF, HMOX2
16nmda44 2810.3NGFR, GDNF, NOS1
17iron44 2410.3HMOX2, DES, GDNF
18adenylate449.3GDNF, DES, NOS1
19ibuprofen44 28 50 24 1113.3NGFR, UGT1A1
20ganglioside449.2NGFR, DES, GDNF
21catecholamine449.2NGFR, GDNF
22h2o2449.2NOS1, DES, GDNF
23ethanol44 50 24 1112.2GDNF, NGFR, DES
24genistein44 28 60 1 24 1114.1GDNF, NOS1, UGT1A1
25nicotine44 28 50 1112.1UGT1A1, NOS1, NGFR
26aspartate449.1GDNF, NOS1, UGT1A1
27indomethacin44 28 60 1112.0NGFR, NOS1, UGT1A1
28cyclic amp44 2410.0GDNF, NGFR, DES
29morphine44 50 28 1112.0UGT1A1, NOS1
30dopamine44 28 24 1111.9GDNF, NGFR, HMOX2, NOS1
31superoxide44 249.9NGFR, NOS1, HMOX2, GDNF
32glutamate448.9GDNF, HMOX2, NOS1, NGFR
33testosterone44 60 24 1111.9UGT1A1, NOS1, DES
34vegf448.8GDNF, NOS1, DES, NGFR
35thymidine44 249.8NGFR, UGT1A1, DES
36cysteine448.8NOS1, GDNF, DES, NGFR
37glucose448.7NGFR, GDNF, HMOX2, DES
38arginine448.7HMOX2, DES, NOS1, UGT1A1
39dexamethasone44 50 28 1111.6NOS1, GDNF, NGFR, UGT1A1
40steroid448.5UGT1A1, NGFR, DES
41progesterone44 28 60 24 1112.5DES, UGT1A1, NGFR, HMOX2
42serine448.4NKX2-5, NGFR, DES, GDNF, NOS1
43acetylcholine44 50 28 24 1112.4HMOX2, NOS1, NGFR, GDNF, DES
44oxygen44 249.4GDNF, DES, NGFR, HMOX2, NOS1
45calcium44 50 24 1111.4GDNF, NOS1, HMOX2, DES, NGFR
46retinoic acid44 249.1GDNF, DES, UGT1A1, NOS1, NGFR
47nitric oxide44 24 1110.0NKX2-5, GDNF, NOS1, HMOX2, DES, NGFR
48tyrosine448.0NGFR, HMOX2, GDNF, UGT1A1, DES
49estrogen447.6UGT1A1, DES, GDNF, HMOX2, NOS1, NGFR

GO Terms for genes affiliated with Pyloric Stenosis

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Cellular components related to Pyloric Stenosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1sarcolemmaGO:00423839.6NOS1, DES

Biological processes related to Pyloric Stenosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of cardiac muscle contractionGO:00551179.7NOS1, NKX2-5
2heme catabolic processGO:00421679.3HMOX2, UGT1A1
3positive regulation of transcription from RNA polymerase II promoterGO:00459449.2NOS1, NKX2-5, GDNF
4porphyrin-containing compound metabolic processGO:00067789.1HMOX2, UGT1A1
5negative regulation of apoptotic processGO:00430668.6GDNF, NGFR, NKX2-5

Molecular functions related to Pyloric Stenosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein homodimerization activityGO:00428038.7NKX2-5, UGT1A1, GDNF

Sources for Pyloric Stenosis

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet