MCID: PYG006
MIFTS: 46

Pyogenic Granuloma malady

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Pyogenic Granuloma

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Aliases & Descriptions for Pyogenic Granuloma:

Name: Pyogenic Granuloma 45 65
Lobular Capillary Hemangioma 45
 
Granuloma Pyogenic 47

Classifications:



External Ids:

ICD1027 L98.0
UMLS65 C0085653

Summaries for Pyogenic Granuloma

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NIH Rare Diseases:45 Pyogenic granuloma are small, reddish bumps on the skin that bleed easily due to an abnormally high number of blood vessels. they typically occur on the hands, arms, or face. while the exact cause of pyogenic granulomas is unknown, they often appear following injury. pyogenic granuloma is often observed in infancy and childhood, but may also be observed in adults, particularly in pregnant women. small pyogenic granulomas may go away on their own. larger lesions are treated with surgery, electrocautery, freezing, or lasers. last updated: 11/13/2012

MalaCards based summary: Pyogenic Granuloma, also known as lobular capillary hemangioma, is related to embryonal carcinoma and hepatitis. An important gene associated with Pyogenic Granuloma is TEK (TEK Receptor Tyrosine Kinase), and among its related pathways are HIF-1 signaling pathway and Central carbon metabolism in cancer. Affiliated tissues include skin, lung and bone, and related mouse phenotypes are normal and vision/eye.

Wikipedia:68 Pyogenic granuloma (also known as a \"Eruptive hemangioma\", \"Granulation tissue-type hemangioma\",... more...

Related Diseases for Pyogenic Granuloma

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Graphical network of the top 20 diseases related to Pyogenic Granuloma:



Diseases related to pyogenic granuloma

Symptoms for Pyogenic Granuloma

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Drugs & Therapeutics for Pyogenic Granuloma

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Drugs for Pyogenic Granuloma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Propranololapproved, investigational202525-66-64946
Synonyms:
(+-)-Propranolol
(1)-1-(Isopropylamino)-3-(naphthyloxy)propan-2-ol
(R)-(+)-propranolol
(S)-(-)-PROPRANOLOL
1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol
1-(1-Naphthyloxy)-2-hydroxy-3-(isopropylamino)propane
1-(Isopropylamino)-3-(1-naphthoxy)-propan-2-ol
1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol
1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol
1-(naphthalen-1-yloxy)-3-(propan-2-ylamino)propan-2-ol
1-Isopropylamino-3-(1-naphthyloxy)-2-propanol
1-[(1-methylethyl)amino]-3-(naphthalen-1-yloxy)propan-2-ol
1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol
13013-17-7
2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)- (9CI)
2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-, (+-)- (9CI)
3-(naphthalen-1-yloxy)-1-(propan-2-ylamino)propan-2-ol
4199-09-1
4199-10-4
525-66-6
AB00053537
AC1L1JA4
AC1Q1QBV
AC1Q1QC0
AKOS000588816
AY 64043
AY-20694
Anaprilin
Anapriline
Angilol
Apsolol
Avlocardyl
BPBio1_001040
BRD-A10070317-003-06-9
BSPBio_000944
BSPBio_002682
Bedranol
Beprane
Berkolol
Beta Neg
Beta-Neg
Beta-Propranolol
Beta-Tablinen
Beta-Timelets
Betachron
Betadren
Betalong
Bio-0732
Bio1_000367
Bio1_000856
Bio1_001345
C07407
C16H21NO2
CBDivE_006180
CCRIS 3082
CHEBI:8499
CHEMBL27
CID4946
Cardinol
Caridolol
Corpendol
D,L-Propranolol
D08443
DB00571
DL-Propranolol hydrochloride
Deralin
DivK1c_000023
Dl-Propranolol Hydrochloride
Dociton
Duranol
EINECS 208-378-0
EINECS 235-867-6
Efektolol
Elbrol
Etalong
Euprovasin
Frekven
HMS2090L21
Hemangeol
Herzbase
ICI 45520
IDI1_000023
INDERIDE-40/25
INDERIDE-80/25
Ikopal
Inderal
Inderal LA
Inderal La
Inderal hydrochloride
Inderalici
Inderex
Inderide
Inderol
Indobloc
 
Innopran XL
Innopran Xl
Intermigran
KBio1_000023
KBio2_002515
KBio2_005083
KBio2_007651
KBio3_001766
KBio3_001902
KBio3_002993
KBioGR_001347
KBioGR_001684
KBioGR_002515
KBioSS_002523
Kemi
Kemi S
L000679
LS-122410
LS-184129
Lopac0_000896
Migrastat
MolPort-001-794-623
NCGC00015798-07
NCGC00024690-02
NCGC00024690-03
NINDS_000023
NSC91523
Naprilin
Obsidan
Obzidan
Oposim
Oprea1_304193
PDSP1_000767
PDSP1_001607
PDSP1_001608
PDSP2_000755
PDSP2_001591
PDSP2_001592
Prano-Puren
Pranolol
Prestwick0_000952
Prestwick1_000952
Prestwick2_000952
Prestwick3_000952
Pronovan
Propanalol
Propanix
Propanolol
Propanolol [INN-Spanish]
Prophylux
Propranalol
Propranolol
Propranolol (INN)
Propranolol (TN)
Propranolol Hcl
Propranolol Hcl Intensol
Propranolol Hydrochloride
Propranolol [INN:BAN]
Propranololo
Propranololo [DCIT]
Propranololum
Propranololum [INN-Latin]
Propranur
Proprasylyt
Pylapron
R,S-Propranolol Hydrochloride
Racemic propranolol
Rapynogen
Reducor
Reducor Line
Reducor line
SPBio_001361
SPBio_001658
SPBio_003093
STK735510
Sagittol
Sawatal
Servanolol
Sloprolol
Spectrum2_001301
Spectrum2_001699
Spectrum3_000883
Spectrum3_001071
Spectrum4_000974
Spectrum4_001222
Spectrum5_000751
Sumial
Tesnol
UNII-9Y8NXQ24VQ
b-Propranolol
beta-Propranolol
cMAP_000071
etalong
propranolol
propranololo
╬▓-Propranolol
2Neurotransmitter Agents14795
3Adrenergic beta-Antagonists979
4Adrenergic Antagonists1253
5Adrenergic Agents4204

Interventional clinical trials:

idNameStatusNCT IDPhase
1Modified Instrumentation for Surgery to Correct TrichiasisActive, not recruitingNCT00886015Phase 3
2Evaluation of New Biomarkers Predictive of Efficacy Betablockers in PEComa and Vascular Pediatric TumorsRecruitingNCT02334930

Search NIH Clinical Center for Pyogenic Granuloma

Genetic Tests for Pyogenic Granuloma

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Anatomical Context for Pyogenic Granuloma

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MalaCards organs/tissues related to Pyogenic Granuloma:

33
Skin, Lung, Bone, Breast, Endothelial, Monocytes, T cells

Animal Models for Pyogenic Granuloma or affiliated genes

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MGI Mouse Phenotypes related to Pyogenic Granuloma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.4ACTC1, KRAS, TEK, TP53
2MP:00053918.2ANGPT2, KRAS, TEK, TP53
3MP:00053697.9ACTC1, KRAS, TEK, TP53
4MP:00053857.5ACTC1, ANGPT2, KRAS, TEK, TP53
5MP:00053767.4ACTC1, ANGPT2, KRAS, TEK, TP53

Publications for Pyogenic Granuloma

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Articles related to Pyogenic Granuloma:

(show top 50)    (show all 537)
idTitleAuthorsYear
1
Zeta Inhibitory Peptide Disrupts Electrostatic Interactions That Maintain Atypical Protein Kinase C in Its Active Conformation on the Scaffold p62. (26187466)
2015
2
Pituitary volumes are changed in patients with conversion disorder. (25877743)
2015
3
Interest level in 2-year-olds with autism spectrum disorder predicts rate of verbal, nonverbal, and adaptive skill acquisition. (25398893)
2014
4
Glutamate secretion and metabotropic glutamate receptor 1 expression during Kaposi's sarcoma-associated herpesvirus infection promotes cell proliferation. (25299066)
2014
5
Getting too sweet: galectin-1 dysregulation in gestational diabetes mellitus. (24637109)
2014
6
microRNA expression in hepatitis B virus infected primary treeshrew hepatocytes and the independence of intracellular miR-122 level for de novo HBV infection in culture. (24314655)
2014
7
Autoantibodies against p16 protein-derived peptides may be a potential biomarker for non-small cell lung cancer. (24122232)
2014
8
Focal dermal hypoplasia without focal dermal hypoplasia. (24357603)
2013
9
ApoE I/4 is associated with eIF2I+ phosphorylation and impaired learning in young mice. (22883908)
2013
10
A preliminary study of fluvoxamine maleate on depressive state and serum melatonin levels in patients after cerebral infarction. (22687788)
2012
11
Laboratory-acquired brucellosis in Turkey. (22365915)
2012
12
New molecular bridge between RelA/p65 and NF-I_B target genes via histone acetyltransferase TIP60 cofactor. (22249179)
2012
13
Occupation and risk of non-Hodgkin's lymphoma in Singapore. (22116951)
2012
14
Acute diarrhea in hospitalized children of the municipality of Juiz de Fora, MG, Brazil: prevalence and risk factors associated with disease severity. (23329220)
2012
15
Genome-wide association study of copy number variants suggests LTBP1 and FGD4 are important for alcohol drinking. (22295116)
2012
16
Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study. (21852391)
2011
17
N-cadherin expression is correlated with metastasis of spindle cell carcinoma of head and neck region. (21070371)
2011
18
RECK is up-regulated and involved in chondrocyte cloning in human osteoarthritic cartilage. (20395433)
2010
19
Chemoembolization for unresectable hepatocellular carcinoma in patients with or without portal vein thrombosis. (21443089)
2010
20
A case of pyoderma gangrenosum with ulcerative colitis treated with mesalazine. (21165212)
2010
21
Generalized erythema multiforme after localized allergic dermatitis from dark henna tattoo. (19689544)
2009
22
Analysis of p53 gene polymorphisms and protein over-expression in patients with breast cancer. (19048399)
2009
23
Active TGF-beta1 correlates with myofibroblasts and malignancy in the colorectal adenoma-carcinoma sequence. (19462508)
2009
24
Comparison of p.o. or i.v. proton pump inhibitors on 72-h intragastric pH in bleeding peptic ulcer. (19682194)
2009
25
Subtotal splenectomy for splenic abscess. (19680504)
2009
26
The genetics of early telencephalon patterning: some assembly required. (19143049)
2008
27
Urinary protein excretion pattern and renal expression of megalin and cubilin in nephropathic cystinosis. (18455850)
2008
28
Metalloproteinase 9 is the outer executioner of desmoglein 3 in apoptotic keratinocytes. (17448220)
2007
29
Modulation of uterine contractility and peristalsis by oxytocin in estrogen-primed non-pregnant swine uteri. (16720280)
2006
30
Kinetic factors control efficiencies of cell entry, efficacies of entry inhibitors, and mechanisms of adaptation of human immunodeficiency virus. (15767435)
2005
31
Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2. (15641110)
2005
32
Association between the cytotoxic T lymphocyte antigen-4 gene microsatellite polymorphism and inflammatory bowel diseases in the Chinese]. (15059373)
2004
33
Congenital muscular dystrophy with characteristic radiological findings similar to those with Fukuyama congenital muscular dystrophy. (15626844)
2004
34
Coccidiosis control with toltrazuril in conjunction with anticoccidial medicated or nonmedicated feed. (12887207)
2003
35
Serotonin transporter availability correlates with alcohol intake in non-human primates. (12610656)
2003
36
Study on gene expression of TGF beta 1 and its receptor in leukemia cells and the serum TGF beta 1 level in the patients with acute leukemia]. (11263341)
1998
37
A case of acute transverse myelitis affecting the entire length of the spinal cord. (9208267)
1997
38
Chicken ovalbumin upstream promoter transcription factor, a transcriptional activator of HIV-1 gene expression in human brain cells. (8798567)
1996
39
Intradermal dermoid cyst associated with occult spinal dysraphism. (8935344)
1996
40
Unusual endovaginal ultrasonography and magnetic resonance imaging of placental site trophoblastic tumor. (8141195)
1994
41
Contact activation triggers stimulation of the monocyte 5-lipoxygenase pathway via plasmin. (8142660)
1994
42
Enzymatic inactivation of leukotriene B4 by a novel enzyme found in the porcine kidney. Purification and properties of leukotriene B4 12-hydroxydehydrogenase. (8394361)
1993
43
Endoscopic treatment of suprasellar arachnoid cysts. (1481755)
1992
44
The detection of IgE-secreting cells in the peripheral blood of patients with atopic dermatitis. (1560170)
1992
45
Distal ulnar neuropathy from carpal ganglia: a clinical and electrophysiological study. (2837675)
1988
46
Immunohistological diagnosis of a case of composite lymphoma. (3311123)
1987
47
Establishment of erythropoiesis following bone marrow transplantation in a patient with congenital hypoplastic anemia (Diamond-Blackfan syndrome). (786411)
1976
48
Fine structure study of experimental papilledema. (4974862)
1968
49
Glossitis and stomatitis due to penicillin lozenges and troches. (21016496)
1946
50

Variations for Pyogenic Granuloma

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Expression for genes affiliated with Pyogenic Granuloma

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Search GEO for disease gene expression data for Pyogenic Granuloma.

Pathways for genes affiliated with Pyogenic Granuloma

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GO Terms for genes affiliated with Pyogenic Granuloma

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Biological processes related to Pyogenic Granuloma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Tie signaling pathwayGO:00480149.8ANGPT2, TEK
2organ regenerationGO:00311009.8ANGPT2, TEK
3negative regulation of angiogenesisGO:00165259.7ANGPT2, TEK
4positive regulation of angiogenesisGO:00457669.5ANGPT2, TEK
5leukocyte migrationGO:00509009.3ANGPT2, KRAS
6negative regulation of apoptotic processGO:00430668.4ACTC1, TEK, TP53

Sources for Pyogenic Granuloma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet