Aliases & Classifications for Pyogenic Granuloma

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Aliases & Descriptions for Pyogenic Granuloma:

Name: Pyogenic Granuloma 46 66
Lobular Capillary Hemangioma 46
 
Granuloma Pyogenic 48

Classifications:



External Ids:

ICD1028 L98.0

Summaries for Pyogenic Granuloma

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NIH Rare Diseases:46 Pyogenic granuloma are small, reddish bumps on the skin that bleed easily due to an abnormally high number of blood vessels. they typically occur on the hands, arms, or face. while the exact cause of pyogenic granulomas is unknown, they often appear following injury. pyogenic granuloma is often observed in infancy and childhood, but may also be observed in adults, particularly in pregnant women. small pyogenic granulomas may go away on their own. larger lesions are treated with surgery, electrocautery, freezing, or lasers. last updated: 11/13/2012

MalaCards based summary: Pyogenic Granuloma, also known as lobular capillary hemangioma, is related to hepatocellular carcinoma and renal cell carcinoma, and has symptoms including leser-trélat sign An important gene associated with Pyogenic Granuloma is TEK (TEK Receptor Tyrosine Kinase), and among its related pathways are MNAR-PELP1 and Estrogen Receptor Interaction and Angiogenesis (WikiPathways). Affiliated tissues include skin, tongue and bone, and related mouse phenotypes are adipose tissue and no phenotypic analysis.

Wikipedia:69 Pyogenic granuloma (also known as a \"Eruptive hemangioma\", \"Granulation tissue-type hemangioma\",... more...

Related Diseases for Pyogenic Granuloma

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Diseases related to Pyogenic Granuloma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 151)
idRelated DiseaseScoreTop Affiliating Genes
1hepatocellular carcinoma29.1ANGPT2, FGF2, MTOR, STAT3, TP53, VEGFA
2renal cell carcinoma28.9BRAF, FGF2, KRAS, MTOR, VEGFA
3testicular fibroma10.7TEK, TP53
4striatonigral degeneration10.7ANGPT1, ANGPT2, TEK
5acute lymphoblastic leukemia congenital sporadic aniridia10.7ANGPT1, ANGPT2, VEGFA
6apocrine adenoma10.7ANGPT2, TEK, VEGFA
7diabetes mellitus, insulin-dependent, 310.6ANGPT1, ANGPT2, VEGFA
8bile duct mucoepidermoid carcinoma10.6ANGPT1, ESR1, TEK
9leiomyosarcoma10.5ESR1, TP53, VEGFA
10albinism, oculocutaneous, type ia10.5ANGPT1, ANGPT2, TEK, VEGFA
11pleomorphic xanthoastrocytoma10.5BRAF, TP53
12adenofibroma10.5KRAS, NRAS, TP53
13renal fibrosis10.5FGF2, TEK, VEGFA
14iridogoniodysgenesis and skeletal anomalies10.5ACTC1, VEGFA
15split hand split foot malformation autosomal recessive10.5BRAF, TP53
16opportunistic mycosis10.5ANGPT2, FGF2, VEGFA
17mushroom workers' lung10.5ACTC1, TP53
18epithelioid type angiomyolipoma10.5ESR1, MTOR, TP53
19vertebral artery occlusion10.5ANGPT2, TEK, THBS1, VEGFA
20neuropathy, hereditary sensory and autonomic, type vi10.5ANGPT2, FGF2, VEGFA
21lobular neoplasia10.5ESR1, TP53, VEGFA
22pterygium colli mental retardation digital anomalies10.4BRAF, KRAS, NRAS
23hemangioma10.4
24tollner horst manzke syndrome10.4FGF2, PLG, VEGFA
25rad51c-related fanconi anemia10.4BRAF, KRAS, NRAS
26richter's syndrome10.4KRAS, TP53, VEGFA
27placental choriocarcinoma10.4FGF2, TP53, VEGFA
28progesterone-receptor positive breast cancer10.4ESR1, MTOR, TP53
29vibratory urticaria10.4ESR1, KRAS, TP53
30brittle bone syndrome lethal type10.4ESR1, TP53, VEGFA
31chiari malformation type 310.4ACTC1, FGF2
32leukoencephalopathy palmoplantar keratoderma10.4BRAF, KRAS, NRAS
33capillary hemangioma10.4
34zimmermann-laband syndrome 210.4MTOR, STAT3, TP53, VEGFA
35mediastinum teratoma10.4BRAF, KRAS, TP53
36dysostosis10.4ESR1, TP53, VEGFA
37leopard syndrome 110.3BRAF, KRAS, NRAS
38dubin-johnson syndrome10.3BRAF, NRAS, TP53
39small intestinal sarcoma10.3ACTC1, ESR1, TP53
40epidural abscess10.3FGF2, PLG, TEK, VEGFA
41gallbladder papillomatosis10.3KRAS, STAT3, TP53, VEGFA
42frontal sinus squamous cell carcinoma10.3ACTC1, FGF2, TEK
43hartnup disorder10.3KRAS, TP53, VEGFA
44sarcoma10.3
45prostate cancer, hereditary, x-linked 110.3BRAF, ESR1, TP53
46paroxysmal nocturnal hemoglobinuria10.3KRAS, TP53, VEGFA
47dental caries10.3ESR1, KRAS, TP53, VEGFA
48ovarian wilms' cancer10.3ESR1, KRAS, TP53, VEGFA
49prolactin producing pituitary tumor10.3ESR1, FGF2, THBS1
50capillary disease10.3ESR1, FGF2, TP53

Graphical network of the top 20 diseases related to Pyogenic Granuloma:



Diseases related to pyogenic granuloma

Symptoms for Pyogenic Granuloma

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UMLS symptoms related to Pyogenic Granuloma:


leser-trélat sign

Drugs & Therapeutics for Pyogenic Granuloma

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Drugs for Pyogenic Granuloma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Propranolol210525-66-64946
Synonyms:
(+-)-Propranolol
(1)-1-(Isopropylamino)-3-(naphthyloxy)propan-2-ol
(R)-(+)-propranolol
(S)-(-)-PROPRANOLOL
1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol
1-(1-Naphthyloxy)-2-hydroxy-3-(isopropylamino)propane
1-(Isopropylamino)-3-(1-naphthoxy)-propan-2-ol
1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol
1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol
1-(naphthalen-1-yloxy)-3-(propan-2-ylamino)propan-2-ol
1-Isopropylamino-3-(1-naphthyloxy)-2-propanol
1-[(1-methylethyl)amino]-3-(naphthalen-1-yloxy)propan-2-ol
1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol
13013-17-7
2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)- (9CI)
2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-, (+-)- (9CI)
3-(naphthalen-1-yloxy)-1-(propan-2-ylamino)propan-2-ol
4199-09-1
4199-10-4
525-66-6
AB00053537
AC1L1JA4
AC1Q1QBV
AC1Q1QC0
AKOS000588816
AY 64043
AY-20694
Anaprilin
Anapriline
Angilol
Apsolol
Avlocardyl
BPBio1_001040
BRD-A10070317-003-06-9
BSPBio_000944
BSPBio_002682
Bedranol
Beprane
Berkolol
Beta Neg
Beta-Neg
Beta-Propranolol
Beta-Tablinen
Beta-Timelets
Betachron
Betadren
Betalong
Bio-0732
Bio1_000367
Bio1_000856
Bio1_001345
C07407
C16H21NO2
CBDivE_006180
CCRIS 3082
CHEBI:8499
CHEMBL27
CID4946
Cardinol
Caridolol
Corpendol
D,L-Propranolol
D08443
DB00571
DL-Propranolol hydrochloride
Deralin
DivK1c_000023
Dl-Propranolol Hydrochloride
Dociton
Duranol
EINECS 208-378-0
EINECS 235-867-6
Efektolol
Elbrol
Etalong
Euprovasin
Frekven
HMS2090L21
Herzbase
ICI 45520
IDI1_000023
INDERIDE-40/25
INDERIDE-80/25
Ikopal
Inderal
Inderal La
Inderal hydrochloride
Inderalici
Inderex
Inderide
Inderol
Indobloc
InnoPranXL
 
Innopran XL
Intermigran
KBio1_000023
KBio2_002515
KBio2_005083
KBio2_007651
KBio3_001766
KBio3_001902
KBio3_002993
KBioGR_001347
KBioGR_001684
KBioGR_002515
KBioSS_002523
Kemi
Kemi S
L000679
LS-122410
LS-184129
Lopac0_000896
Migrastat
MolPort-001-794-623
NCGC00015798-07
NCGC00024690-02
NCGC00024690-03
NINDS_000023
NSC91523
Naprilin
Obsidan
Obzidan
Oposim
Oprea1_304193
PDSP1_000767
PDSP1_001607
PDSP1_001608
PDSP2_000755
PDSP2_001591
PDSP2_001592
Prano-Puren
Pranolol
Prestwick0_000952
Prestwick1_000952
Prestwick2_000952
Prestwick3_000952
Pronovan
Propanalol
Propanix
Propanolol
Propanolol [INN-Spanish]
Prophylux
Propranalol
Propranolol
Propranolol (INN)
Propranolol (TN)
Propranolol Hcl
Propranolol Hcl Intensol
Propranolol Hydrochloride
Propranolol [INN:BAN]
Propranololo
Propranololo [DCIT]
Propranololum
Propranololum [INN-Latin]
Propranur
Proprasylyt
Pylapron
R,S-Propranolol Hydrochloride
Racemic propranolol
Rapynogen
Reducor
Reducor Line
Reducor line
SPBio_001361
SPBio_001658
SPBio_003093
STK735510
Sagittol
Sawatal
Servanolol
Sloprolol
Spectrum2_001301
Spectrum2_001699
Spectrum3_000883
Spectrum3_001071
Spectrum4_000974
Spectrum4_001222
Spectrum5_000751
Sumial
Tesnol
UNII-9Y8NXQ24VQ
b-Propranolol
beta-Propranolol
cMAP_000071
etalong
propranolol
propranololo
β-Propranolol

Interventional clinical trials:

idNameStatusNCT IDPhase
1Modified Instrumentation for Surgery to Correct TrichiasisActive, not recruitingNCT00886015Phase 3
2Evaluation of New Biomarkers Predictive of Efficacy Betablockers in PEComa and Vascular Pediatric TumorsCompletedNCT02334930

Search NIH Clinical Center for Pyogenic Granuloma

Genetic Tests for Pyogenic Granuloma

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Anatomical Context for Pyogenic Granuloma

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MalaCards organs/tissues related to Pyogenic Granuloma:

34
Skin, Tongue, Bone, Colon, Endothelial, Bone marrow, Testes

Animal Models for Pyogenic Granuloma or affiliated genes

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MGI Mouse Phenotypes related to Pyogenic Granuloma:

39 (show all 28)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.6ATF2, BRAF, ESR1, MTOR, STAT3, TP53
2MP:00030128.4EFNB2, ESR1, KRAS, MTOR, NRAS, TP53
3MP:00053828.2BRAF, EFNB2, KRAS, NRAS, TP53, TP63
4MP:00053777.9ATF2, BRAF, EFNB2, FGF2, KRAS, TP53
5MP:00053707.8ATF2, BRAF, ESR1, KRAS, NRAS, PLG
6MP:00053717.3ATF2, ESR1, KRAS, NRAS, THBS1, TP53
7MP:00053677.0ANGPT1, BRAF, EFNB2, ESR1, KRAS, MTOR
8MP:00053896.8BRAF, EFNB2, ESR1, FGF2, KRAS, PLG
9MP:00053816.7ANGPT2, BRAF, EFNB2, ESR1, KRAS, NRAS
10MP:00107716.6ANGPT2, ATF2, BRAF, EFNB2, ESR1, KRAS
11MP:00053796.5BRAF, EFNB2, ESR1, KRAS, MTOR, NRAS
12MP:00020066.3ATF2, BRAF, ESR1, FGF2, KRAS, NRAS
13MP:00028736.2ACTC1, ATF2, BRAF, EFNB2, ESR1, KRAS
14MP:00053695.9ACTC1, ANGPT1, BRAF, EFNB2, EPHB4, ESR1
15MP:00053885.9ANGPT2, ATF2, BRAF, EFNB2, ESR1, KRAS
16MP:00036315.9ANGPT1, ATF2, BRAF, EFNB2, ESR1, FGF2
17MP:00053975.8ATF2, BRAF, EFNB2, ESR1, FGF2, KRAS
18MP:00053865.7ATF2, BRAF, EFNB2, ESR1, FGF2, KRAS
19MP:00053905.6ATF2, BRAF, EFNB2, ESR1, FGF2, KRAS
20MP:00053805.4ANGPT1, ATF2, BRAF, EFNB2, EPHB4, ESR1
21MP:00053915.2ANGPT1, ANGPT2, ATF2, BRAF, EFNB2, FGF2
22MP:00053874.9ANGPT1, ANGPT2, ATF2, BRAF, EFNB2, EPHB4
23MP:00053844.9ACTC1, ANGPT2, ATF2, BRAF, EFNB2, ESR1
24MP:00053784.1ACTC1, ANGPT1, ATF2, BRAF, EFNB2, EPHB4
25MP:00053764.0ACTC1, ANGPT1, ANGPT2, ATF2, BRAF, EFNB2
26MP:00053853.9ACTC1, ANGPT1, ANGPT2, ATF2, BRAF, EFNB2
27MP:00107683.8ACTC1, ANGPT1, ANGPT2, ATF2, BRAF, EFNB2

Publications for Pyogenic Granuloma

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Articles related to Pyogenic Granuloma:

(show top 50)    (show all 569)
idTitleAuthorsYear
1
Pyogenic granuloma in patients treated with selective BRAF inhibitors: another manifestation of paradoxical pathway activation. (27116335)
2016
2
CO2 Laser Excision of a Pyogenic Granuloma Associated with Dental Implants: A Case Report and Review of the Literature. (27420917)
2016
3
Capillary hemangioma or pyogenic granuloma. (27041829)
2016
4
Demographics and etiologic factors of nasal pyogenic granuloma. (27122134)
2016
5
Angioleiomyoma of Gingiva Masquerading as Pyogenic Granuloma. (27504561)
2016
6
Atypical Presentation of a Complex Eyelid Choristoma Mimicking a Chalazion with Pyogenic Granuloma. (27210602)
2016
7
Nodular swelling on the lower lip; pyogenic granuloma. (25525490)
2014
8
Pyogenic granuloma of the gingiva: A misnomer? - A case report and review of literature. (24174735)
2013
9
Case of the month. Pyogenic granuloma. (23923461)
2013
10
Oral capillary haemangioma mimicking pyogenic granuloma: a challenge for diagnosis and management. (23417375)
2013
11
Painless red lesion on the tongue. Pyogenic granuloma. (22414511)
2012
12
Photodynamic therapy with 5-aminolevulinic acid intralesional injection for pyogenic granuloma. (22250252)
2012
13
"Pyogenic granuloma - Hyperplastic lesion of the gingiva: case reports". (23091574)
2012
14
Pyogenic granuloma: treatment with the 1,064-nm long-pulsed neodymium-doped yttrium aluminum garnet laser in 20 patients. (22272571)
2012
15
A case of childhood subcutaneous pyogenic granuloma (lobular capillary hemangioma). (21196416)
2012
16
Pregnancy-associated pyogenic granuloma of the lip: a case report. (21970285)
2011
17
Pyogenic granuloma. (21119538)
2011
18
Pyogenic granuloma of the foot with satellitosis: a role for conservative management. (21291657)
2011
19
Pyogenic granuloma of the distal trachea: a case report. (23208576)
2011
20
Clinical inquiries. What's the best treatment for pyogenic granuloma? (20074501)
2010
21
Complete resolution of a recurrent giant pyogenic granuloma on the palm of the hand following single dose of intralesional bleomycin injection. (19632910)
2010
22
Congenital disseminated pyogenic granuloma. (19706097)
2009
23
Pyogenic granuloma: an unusual cause of massive gastrointestinal bleeding from the small bowel. (19373418)
2009
24
Pyogenic granuloma as a surrogate indicator of deep seated foreign bodies: a case report. (19918522)
2009
25
Pyogenic granuloma, peripheral giant cell granuloma and peripheral ossifying fibroma: retrospective analysis of 138 cases. (18496485)
2008
26
Extragingival pyogenic granuloma: a case report. (19055747)
2008
27
Pyogenic granuloma. (18174801)
2008
28
Nasal pyogenic granuloma. (17210349)
2007
29
Recurrent intraoral pyogenic granuloma with satellitosis treated with corticosteroids. (16390473)
2006
30
Diagnostic quiz. Case no. 1. Pyogenic granuloma. (19226729)
2006
31
Intravenous pyogenic granuloma or intravenous lobular capillary hemangioma. (15565332)
2005
32
Is pyogenic granuloma associated with Bartonella infection? (16310070)
2005
33
Assessment of angiogenic markers in oral hemangiomas and pyogenic granulomas. (16005715)
2005
34
Chronic Staphylococcus aureus infection leading to pyogenic granuloma and preventing socket re-epithelialization after orbital exenteration. (15942503)
2005
35
Oral pyogenic granuloma in Jordanians: a retrospective analysis of 108 cases. (14613084)
2003
36
Pediatric pyogenic granuloma of the glans penis. (12639669)
2003
37
Pyogenic granuloma-like lesions during capecitabine therapy. (12452889)
2002
38
Laryngeal pyogenic granulomas do not express oestrogen or progesterone receptors. (11667991)
2001
39
Onychomadesis and pyogenic granuloma following cast immobilization. (11176706)
2001
40
Expression of Tie-2, angiopoietin-1, angiopoietin-2, ephrinB2 and EphB4 in pyogenic granuloma of human gingiva implicates their roles in inflammatory angiogenesis. (10929871)
2000
41
Pyogenic granuloma: a complication of transconjunctival incisions. (10744252)
2000
42
Cutaneous metastasis from hepatocellular carcinoma resembling pyogenic granuloma. (10233658)
1999
43
Oral angiosarcoma misdiagnosed as a pyogenic granuloma. (9580135)
1998
44
Clinical diagnosis and management of hormonally responsive oral pregnancy tumor (pyogenic granuloma). (8829057)
1996
45
Oral pyogenic granuloma in pregnancy. (9764875)
1995
46
Pyogenic granuloma as a cause of bone loss in a twelve-year-old child: report of case. (8182202)
1994
47
Pyogenic granuloma following treatment of verruca vulgaris with cryotherapy and Duoplant. (2022132)
1991
48
Localized vs generalized pyogenic granuloma. A clinicopathologic study. (2036033)
1991
49
A pyogenic granuloma and an irritation fibroma--case report. (297013)
1979
50
Pyogenic granuloma of the nasal cavity. (13902293)
1962

Variations for Pyogenic Granuloma

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Expression for genes affiliated with Pyogenic Granuloma

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Search GEO for disease gene expression data for Pyogenic Granuloma.

Pathways for genes affiliated with Pyogenic Granuloma

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Pathways related to Pyogenic Granuloma according to GeneCards Suite gene sharing:

(show top 50)    (show all 96)
idSuper pathwaysScoreTop Affiliating Genes
19.6ESR1, KRAS, NRAS
2
Show member pathways
9.5ANGPT1, FGF2, TEK, VEGFA
39.4KRAS, MTOR, NRAS, TP53
49.3BRAF, KRAS, NRAS, TP53
5
Show member pathways
9.3ANGPT1, ANGPT2, KRAS, NRAS, TEK
6
Show member pathways
9.3FGF2, KRAS, NRAS, STAT3
79.2TP53, TP63, TP73
89.2ANGPT1, ANGPT2, MTOR, STAT3, TEK, VEGFA
99.1ESR1, KRAS, MTOR, NRAS, TP53
109.1BRAF, KRAS, STAT3, TP53, VEGFA
11
Show member pathways
9.1BRAF, KRAS, MTOR, TEK, TP53
12
Show member pathways
9.1BRAF, KRAS, MTOR, NRAS, STAT3
139.1BRAF, KRAS, NRAS, STAT3, TP53
149.1BRAF, KRAS, MTOR, NRAS, TP53
15
Show member pathways
9.1BRAF, KRAS, MTOR, NRAS, TP53
169.0BRAF, FGF2, KRAS, NRAS, VEGFA
17
Show member pathways
9.0ANGPT1, ANGPT2, FGF2, PLG, STAT3, TEK
18
Show member pathways
8.9BRAF, KRAS, NRAS, STAT3, TP53, VEGFA
19
Show member pathways
8.9ANGPT2, EFNB2, FGF2, TEK, THBS1
20
Show member pathways
8.9BRAF, KRAS, MTOR, NRAS, STAT3, TP53
21
Show member pathways
8.9BRAF, KRAS, MTOR, NRAS, STAT3, TP53
228.9BRAF, KRAS, NRAS, THBS1, TP53, VEGFA
238.8BRAF, ESR1, KRAS, MTOR, TP53, VEGFA
248.7ESR1, FGF2, KRAS, THBS1, TP53, VEGFA
258.7ATF2, BRAF, KRAS, TP53
26
Show member pathways
8.7BRAF, FGF2, KRAS, MTOR, NRAS, TP53
278.6ATF2, KRAS, NRAS, STAT3, TP53
28
Show member pathways
8.6ATF2, KRAS, MTOR, NRAS, TP53
298.6ANGPT2, EFNB2, EPHB4, FGF2, TEK
308.4ATF2, BRAF, ESR1, KRAS, MTOR
318.4ATF2, FGF2, STAT3, TP63, VEGFA
32
Show member pathways
8.3ANGPT1, ANGPT2, KRAS, NRAS, PLG, TEK
338.3BRAF, FGF2, KRAS, MTOR, NRAS, STAT3
34
Show member pathways
8.3ATF2, BRAF, KRAS, NRAS, STAT3, TP53
358.3KRAS, MTOR, NRAS, STAT3, THBS1, TP53
36
Show member pathways
8.3ATF2, BRAF, ESR1, KRAS, STAT3, VEGFA
37
Show member pathways
8.1ANGPT1, ANGPT2, BRAF, FGF2, KRAS, NRAS
38
Show member pathways
8.0ATF2, BRAF, KRAS, MTOR, NRAS, STAT3
39
Show member pathways
7.9ANGPT1, ANGPT2, ATF2, FGF2, KRAS, MTOR
40
Show member pathways
7.8BRAF, ESR1, KRAS, MTOR, NRAS, STAT3
41
Show member pathways
7.8ATF2, BRAF, KRAS, MTOR, NRAS, PLG
427.7BRAF, ESR1, FGF2, KRAS, MTOR, NRAS
43
Show member pathways
7.4ANGPT1, ANGPT2, BRAF, EPHB4, KRAS, MTOR
44
Show member pathways
7.4BRAF, EPHB4, ESR1, FGF2, KRAS, NRAS
45
Show member pathways
7.2ANGPT1, BRAF, EFNB2, EPHB4, FGF2, KRAS
467.2ANGPT1, ANGPT2, ATF2, FGF2, KRAS, MTOR
47
Show member pathways
6.8ANGPT1, ANGPT2, ATF2, EPHB4, FGF2, KRAS
48
Show member pathways
6.6ATF2, BRAF, EPHB4, ESR1, FGF2, KRAS
49
Show member pathways
6.3ANGPT1, ANGPT2, ATF2, BRAF, EPHB4, FGF2
50
Show member pathways
5.9ANGPT1, ANGPT2, ATF2, BRAF, EPHB4, ESR1

GO Terms for genes affiliated with Pyogenic Granuloma

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Cellular components related to Pyogenic Granuloma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:003109310.4PLG, THBS1, VEGFA
2nuclear chromatinGO:00007909.7ESR1, STAT3, TP53, TP63
3extracellular regionGO:00055768.4ANGPT1, ANGPT2, EPHB4, FGF2, PLG, TEK
4cytoplasmGO:00057375.5ACTC1, ATF2, BRAF, ESR1, FGF2, KRAS

Biological processes related to Pyogenic Granuloma according to GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idNameGO IDScoreTop Affiliating Genes
1glomerulus vasculature developmentGO:007201210.8ANGPT1, ANGPT2
2regulation of cGMP metabolic processGO:003082310.7THBS1, VEGFA
3Tie signaling pathwayGO:004801410.6ANGPT1, ANGPT2, TEK
4positive regulation of phospholipase C activityGO:001086310.6ESR1, FGF2
5negative regulation of fibrinolysisGO:005191810.5PLG, THBS1
6sprouting angiogenesisGO:000204010.4ANGPT1, TEK, THBS1
7negative regulation of endothelial cell apoptotic processGO:200035210.4ANGPT1, BRAF, TEK
8negative regulation of fibroblast migrationGO:001076410.3BRAF, FGF2
9negative regulation of angiogenesisGO:001652510.3ANGPT2, TEK, THBS1
10response to peptide hormoneGO:004343410.3BRAF, STAT3, TEK
11positive chemotaxisGO:005091810.3ANGPT1, FGF2, VEGFA
12positive regulation of blood vessel endothelial cell migrationGO:004353610.1ANGPT1, FGF2, THBS1, VEGFA
13positive regulation of peptidyl-tyrosine phosphorylationGO:005073110.1ANGPT1, MTOR, TP53, VEGFA
14positive regulation of peptidyl-serine phosphorylationGO:003313810.1ANGPT1, BRAF, VEGFA
15negative regulation of blood vessel endothelial cell migrationGO:004353710.1ANGPT2, FGF2, THBS1
16positive regulation of MAP kinase activityGO:004340610.1FGF2, KRAS, VEGFA
17positive regulation of endothelial cell proliferationGO:000193810.1FGF2, MTOR, TEK, VEGFA
18positive regulation of epithelial cell proliferationGO:005067910.0ESR1, FGF2, VEGFA
19somatic stem cell population maintenanceGO:003501910.0BRAF, FGF2, STAT3
20cell agingGO:00075699.9MTOR, TP53, TP63
21DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:00069789.9TP53, TP63, TP73
22positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:19007409.9TP53, TP63, TP73
23heart morphogenesisGO:00030079.9EPHB4, MTOR, VEGFA
24positive regulation of endothelial cell migrationGO:00105959.9ANGPT1, FGF2, TEK, THBS1, VEGFA
25mitotic G1 DNA damage checkpointGO:00315719.9TP53, TP63, TP73
26response to X-rayGO:00101659.9TP53, TP63, TP73
27cellular response to UVGO:00346449.8TP53, TP63, TP73
28response to gamma radiationGO:00103329.8TP53, TP63, TP73
29intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorGO:00427719.8TP53, TP63, TP73
30positive regulation of angiogenesisGO:00457669.8ANGPT2, FGF2, TEK, THBS1, VEGFA
31positive regulation of protein kinase B signalingGO:00518979.7ANGPT1, FGF2, MTOR, TEK, THBS1
32response to hypoxiaGO:00016669.7ANGPT2, TEK, THBS1, VEGFA
33positive regulation of protein phosphorylationGO:00019349.7FGF2, KRAS, MTOR, TEK, VEGFA
34cell cycle arrestGO:00070509.7MTOR, THBS1, TP53, TP73
35leukocyte migrationGO:00509009.6ANGPT1, ANGPT2, KRAS, NRAS, TEK
36Ras protein signal transductionGO:00072659.5FGF2, KRAS, NRAS, TP53
37cell migration involved in sprouting angiogenesisGO:00020429.5EFNB2, EPHB4, FGF2, VEGFA
38regulation of apoptotic processGO:00429819.4ESR1, TP53, TP63, TP73
39negative regulation of neuron apoptotic processGO:00435249.4ANGPT1, BRAF, KRAS, TP73
40animal organ morphogenesisGO:00098879.3BRAF, EFNB2, FGF2, TP63
41visual learningGO:00085429.3BRAF, KRAS, MTOR
42MAPK cascadeGO:00001659.3ANGPT1, BRAF, FGF2, KRAS, NRAS, TEK
43angiogenesisGO:00015259.2ANGPT1, ANGPT2, EPHB4, FGF2, TEK, VEGFA
44positive regulation of ERK1 and ERK2 cascadeGO:00703749.1ANGPT1, BRAF, ESR1, FGF2, TEK
45positive regulation of transcription, DNA-templatedGO:00458938.7ESR1, FGF2, STAT3, TP53, TP63, TP73
46positive regulation of gene expressionGO:00106288.4ACTC1, BRAF, FGF2, KRAS, MTOR, STAT3
47transcription from RNA polymerase II promoterGO:00063668.2ATF2, ESR1, STAT3, TP53, TP63, TP73
48negative regulation of apoptotic processGO:00430668.2ACTC1, ANGPT1, BRAF, STAT3, TEK, THBS1
49negative regulation of transcription from RNA polymerase II promoterGO:00001227.6ATF2, ESR1, STAT3, TP53, TP63, TP73
50positive regulation of transcription from RNA polymerase II promoterGO:00459447.3ATF2, ESR1, FGF2, STAT3, TP53, TP63

Molecular functions related to Pyogenic Granuloma according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1receptor tyrosine kinase bindingGO:003097110.3ANGPT1, ANGPT2, TP53
2p53 bindingGO:00020399.9TP53, TP63, TP73
3damaged DNA bindingGO:00036849.8TP53, TP63, TP73
4transcription regulatory region DNA bindingGO:00442129.5STAT3, TP53, TP63, TP73
5protein kinase bindingGO:00199018.8ATF2, MTOR, STAT3, TP53, TP73
6transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingGO:00010778.7ATF2, ESR1, STAT3, TP63, TP73
7chromatin bindingGO:00036828.4ATF2, ESR1, TP53, TP63, TP73
8transcription factor bindingGO:00081348.2ATF2, ESR1, STAT3, TP53, TP73
9identical protein bindingGO:00428027.9BRAF, ESR1, STAT3, THBS1, TP53, TP63
10protein bindingGO:00055154.1ANGPT2, ATF2, BRAF, EFNB2, EPHB4, ESR1

Sources for Pyogenic Granuloma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
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30ICD9CM
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32KEGG
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39MGI
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65Tumor Gene Family of Databases
66UMLS
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