MCID: PYG006
MIFTS: 37

Pyogenic Granuloma malady

Rare diseases, Skin diseases categories

Aliases & Classifications for Pyogenic Granuloma

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Sources:
45NIH Rare Diseases, 65UMLS, 47Novoseek, 27ICD10
See all sources

Aliases & Descriptions for Pyogenic Granuloma:

Name: Pyogenic Granuloma 45 65
Lobular Capillary Hemangioma 45
 
Granuloma Pyogenic 47


Classifications:



External Ids:

ICD1027 L98.0

Summaries for Pyogenic Granuloma

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NIH Rare Diseases:45 Pyogenic granuloma are small, reddish bumps on the skin that bleed easily due to an abnormally high number of blood vessels. they typically occur on the hands, arms, or face. while the exact cause of pyogenic granulomas is unknown, they often appear following injury. pyogenic granuloma is often observed in infancy and childhood, but may also be observed in adults, particularly in pregnant women. small pyogenic granulomas may go away on their own. larger lesions are treated with surgery, electrocautery, freezing, or lasers. last updated: 11/13/2012

MalaCards based summary: Pyogenic Granuloma, also known as lobular capillary hemangioma, is related to retinitis and rheumatoid arthritis. An important gene associated with Pyogenic Granuloma is TEK (TEK Tyrosine Kinase, Endothelial), and among its related pathways are and G-protein signaling_H-RAS regulation pathway. Affiliated tissues include skin, tongue and bone, and related mouse phenotypes are muscle and growth/size/body.

Wikipedia:68 Pyogenic granuloma (also known as a \"Eruptive hemangioma\", \"Granulation tissue-type hemangioma\",... more...

Related Diseases for Pyogenic Granuloma

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Graphical network of the top 20 diseases related to Pyogenic Granuloma:



Diseases related to pyogenic granuloma

Symptoms for Pyogenic Granuloma

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Drugs & Therapeutics for Pyogenic Granuloma

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Drugs for Pyogenic Granuloma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Propranololapproved, investigational194525-66-64946
Synonyms:
(+-)-Propranolol
(1)-1-(Isopropylamino)-3-(naphthyloxy)propan-2-ol
(R)-(+)-propranolol
(S)-(-)-PROPRANOLOL
1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol
1-(1-Naphthyloxy)-2-hydroxy-3-(isopropylamino)propane
1-(Isopropylamino)-3-(1-naphthoxy)-propan-2-ol
1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol
1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol
1-(naphthalen-1-yloxy)-3-(propan-2-ylamino)propan-2-ol
1-Isopropylamino-3-(1-naphthyloxy)-2-propanol
1-[(1-methylethyl)amino]-3-(naphthalen-1-yloxy)propan-2-ol
1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol
13013-17-7
2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)- (9CI)
2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-, (+-)- (9CI)
3-(naphthalen-1-yloxy)-1-(propan-2-ylamino)propan-2-ol
4199-09-1
4199-10-4
525-66-6
AB00053537
AC1L1JA4
AC1Q1QBV
AC1Q1QC0
AKOS000588816
AY 64043
AY-20694
Anaprilin
Anapriline
Angilol
Apsolol
Avlocardyl
BPBio1_001040
BRD-A10070317-003-06-9
BSPBio_000944
BSPBio_002682
Bedranol
Beprane
Berkolol
Beta Neg
Beta-Neg
Beta-Propranolol
Beta-Tablinen
Beta-Timelets
Betachron
Betadren
Betalong
Bio-0732
Bio1_000367
Bio1_000856
Bio1_001345
C07407
C16H21NO2
CBDivE_006180
CCRIS 3082
CHEBI:8499
CHEMBL27
CID4946
Cardinol
Caridolol
Corpendol
D,L-Propranolol
D08443
DB00571
DL-Propranolol hydrochloride
Deralin
DivK1c_000023
Dl-Propranolol Hydrochloride
Dociton
Duranol
EINECS 208-378-0
EINECS 235-867-6
Efektolol
Elbrol
Etalong
Euprovasin
Frekven
HMS2090L21
Hemangeol
Herzbase
ICI 45520
IDI1_000023
INDERIDE-40/25
INDERIDE-80/25
Ikopal
Inderal
Inderal LA
Inderal La
Inderal hydrochloride
Inderalici
Inderex
Inderide
Inderol
Indobloc
 
Innopran XL
Innopran Xl
Intermigran
KBio1_000023
KBio2_002515
KBio2_005083
KBio2_007651
KBio3_001766
KBio3_001902
KBio3_002993
KBioGR_001347
KBioGR_001684
KBioGR_002515
KBioSS_002523
Kemi
Kemi S
L000679
LS-122410
LS-184129
Lopac0_000896
Migrastat
MolPort-001-794-623
NCGC00015798-07
NCGC00024690-02
NCGC00024690-03
NINDS_000023
NSC91523
Naprilin
Obsidan
Obzidan
Oposim
Oprea1_304193
PDSP1_000767
PDSP1_001607
PDSP1_001608
PDSP2_000755
PDSP2_001591
PDSP2_001592
Prano-Puren
Pranolol
Prestwick0_000952
Prestwick1_000952
Prestwick2_000952
Prestwick3_000952
Pronovan
Propanalol
Propanix
Propanolol
Propanolol [INN-Spanish]
Prophylux
Propranalol
Propranolol
Propranolol (INN)
Propranolol (TN)
Propranolol Hcl
Propranolol Hcl Intensol
Propranolol Hydrochloride
Propranolol [INN:BAN]
Propranololo
Propranololo [DCIT]
Propranololum
Propranololum [INN-Latin]
Propranur
Proprasylyt
Pylapron
R,S-Propranolol Hydrochloride
Racemic propranolol
Rapynogen
Reducor
Reducor Line
Reducor line
SPBio_001361
SPBio_001658
SPBio_003093
STK735510
Sagittol
Sawatal
Servanolol
Sloprolol
Spectrum2_001301
Spectrum2_001699
Spectrum3_000883
Spectrum3_001071
Spectrum4_000974
Spectrum4_001222
Spectrum5_000751
Sumial
Tesnol
UNII-9Y8NXQ24VQ
b-Propranolol
beta-Propranolol
cMAP_000071
etalong
propranolol
propranololo
╬▓-Propranolol

Interventional clinical trials:

idNameStatusNCT IDPhase
1Modified Instrumentation for Surgery to Correct TrichiasisActive, not recruitingNCT00886015Phase 3
2Evaluation of New Biomarkers Predictive of Efficacy Betablockers in PEComa and Vascular Pediatric TumorsRecruitingNCT02334930

Search NIH Clinical Center for Pyogenic Granuloma

Genetic Tests for Pyogenic Granuloma

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Anatomical Context for Pyogenic Granuloma

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MalaCards organs/tissues related to Pyogenic Granuloma:

33
Skin, Tongue, Bone, Colon, Endothelial, Trachea, Testes

Animal Models for Pyogenic Granuloma or affiliated genes

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MGI Mouse Phenotypes related to Pyogenic Granuloma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.2ACTC1, ANGPT1, TEK, VEGFA
2MP:00053787.6ACTC1, ANGPT1, PLG, TEK, VEGFA
3MP:00053857.1ACTC1, ANGPT1, ANGPT2, PLG, TEK, VEGFA
4MP:00107686.8ACTC1, ANGPT1, ANGPT2, PLG, TEK, VEGFA

Publications for Pyogenic Granuloma

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Articles related to Pyogenic Granuloma:

(show top 50)    (show all 533)
idTitleAuthorsYear
1
Pyogenic granuloma in differential iron deficiency diagnosis. (25698283)
2015
2
Cutaneous Leishmaniasis Mimicking A Pyogenic Granuloma. (24923493)
2014
3
Pyogenic Granuloma: Surgical Treatment with Er:YAG Laser. (25653822)
2014
4
Pyogenic granuloma of the ileum diagnosed by double-balloon enteroscopy. (25224187)
2014
5
Pyogenic granuloma of the ileum depicted by small-bowel radiography, capsule endoscopy and double balloon endoscopy. (25553608)
2014
6
Nodular swelling on the lower lip; pyogenic granuloma. (25525490)
2014
7
Pyogenic granuloma of the gingiva: A misnomer? - A case report and review of literature. (24174735)
2013
8
Case of the month. Pyogenic granuloma. (23923461)
2013
9
Esophageal pyogenic granuloma: endosonographic findings and endoscopic treatments. (23423701)
2013
10
Oral capillary haemangioma mimicking pyogenic granuloma: a challenge for diagnosis and management. (23417375)
2013
11
Painless red lesion on the tongue. Pyogenic granuloma. (22414511)
2012
12
Exuberant pyogenic granuloma in extragingival site. (22936151)
2012
13
Photodynamic therapy with 5-aminolevulinic acid intralesional injection for pyogenic granuloma. (22250252)
2012
14
Giant cell tumor of tendon sheath mimicking pyogenic granuloma in the index finger pulp: a case report. (22351549)
2012
15
"Pyogenic granuloma - Hyperplastic lesion of the gingiva: case reports". (23091574)
2012
16
Concurrent occurrence of mucocele and pyogenic granuloma. (22028553)
2011
17
Pregnancy-associated pyogenic granuloma of the lip: a case report. (21970285)
2011
18
Clinical inquiries. What's the best treatment for pyogenic granuloma? (20074501)
2010
19
Oral pyogenic granuloma: a retrospective analysis of 293 cases in a Brazilian population. (20417014)
2010
20
Oral pathology quiz. Case number 2. Pyogenic granuloma. (20658767)
2010
21
Multiple pyogenic granuloma of the penis in a four-year-old child: a case report. (19918487)
2009
22
Congenital disseminated pyogenic granuloma. (19706097)
2009
23
Pyogenic granuloma: an unusual cause of massive gastrointestinal bleeding from the small bowel. (19373418)
2009
24
Pyogenic granuloma: lobular capillary hemangioma in the upper lip of a 24-month-old child: case report. (19941768)
2009
25
Pyogenic granuloma, peripheral giant cell granuloma and peripheral ossifying fibroma: retrospective analysis of 138 cases. (18496485)
2008
26
Extragingival pyogenic granuloma: a case report. (19055747)
2008
27
Successful treatment of a therapy-resistant pyogenic granuloma with topical imiquimod 5% cream. (16766338)
2006
28
Comparison of cryotherapy and curettage for the treatment of pyogenic granuloma: a randomized trial. (16536810)
2006
29
Recurrent intraoral pyogenic granuloma with satellitosis treated with corticosteroids. (16390473)
2006
30
Intravenous pyogenic granuloma or intravenous lobular capillary hemangioma. (15565332)
2005
31
Is pyogenic granuloma associated with Bartonella infection? (16310070)
2005
32
Metastatic hepatocellular carcinoma of gingiva mimicking pyogenic granuloma. (12894096)
2003
33
Oral pyogenic granuloma in Jordanians: a retrospective analysis of 108 cases. (14613084)
2003
34
Pediatric pyogenic granuloma of the glans penis. (12639669)
2003
35
Pyogenic granuloma-like lesions during capecitabine therapy. (12452889)
2002
36
Laryngeal pyogenic granulomas do not express oestrogen or progesterone receptors. (11667991)
2001
37
Onychomadesis and pyogenic granuloma following cast immobilization. (11176706)
2001
38
Pyogenic granuloma: who are you? (11495513)
2001
39
Expression of Tie-2, angiopoietin-1, angiopoietin-2, ephrinB2 and EphB4 in pyogenic granuloma of human gingiva implicates their roles in inflammatory angiogenesis. (10929871)
2000
40
Pyogenic granuloma: a complication of transconjunctival incisions. (10744252)
2000
41
Cutaneous metastasis from hepatocellular carcinoma resembling pyogenic granuloma. (10233658)
1999
42
Plaque radiation therapy for recurrent conjunctival pyogenic granuloma. (9565059)
1998
43
Pyogenic granuloma of the cornea. (9630306)
1998
44
Oral angiosarcoma misdiagnosed as a pyogenic granuloma. (9580135)
1998
45
Oral pyogenic granuloma in pregnancy. (9764875)
1995
46
Intraoral pyogenic granuloma after allogeneic bone marrow transplant. Report of three cases. (7838468)
1994
47
Pyogenic granuloma following treatment of verruca vulgaris with cryotherapy and Duoplant. (2022132)
1991
48
The pyogenic granuloma. (6393917)
1984
49
A pyogenic granuloma and an irritation fibroma--case report. (297013)
1979
50
Pyogenic granuloma of the nasal cavity. (13902293)
1962

Variations for Pyogenic Granuloma

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Expression for genes affiliated with Pyogenic Granuloma

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Search GEO for disease gene expression data for Pyogenic Granuloma.

Pathways for genes affiliated with Pyogenic Granuloma

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GO Terms for genes affiliated with Pyogenic Granuloma

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Cellular components related to Pyogenic Granuloma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1actin filamentGO:00058849.9ACTC1, TEK
2microvillusGO:00059029.9ANGPT1, TEK
3platelet alpha granule lumenGO:00310939.7PLG, VEGFA
4cell surfaceGO:00099868.6PLG, TEK, VEGFA
5extracellular spaceGO:00056157.5ACTC1, ANGPT1, ANGPT2, PLG, VEGFA
6extracellular regionGO:00055767.3ANGPT1, ANGPT2, PLG, TEK, VEGFA

Biological processes related to Pyogenic Granuloma according to GeneCards Suite gene sharing:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of cell-substrate adhesionGO:001081210.1ANGPT2, PLG
2glomerulus vasculature developmentGO:007201210.1ANGPT1, ANGPT2
3negative regulation of endothelial cell apoptotic processGO:200035210.1ANGPT1, TEK
4negative regulation of angiogenesisGO:001652510.0ANGPT2, TEK
5sprouting angiogenesisGO:000204010.0ANGPT1, TEK
6positive regulation of phosphatidylinositol 3-kinase signalingGO:00140689.9ANGPT1, TEK
7positive regulation of protein kinase B signalingGO:00518979.9ANGPT1, TEK
8organ regenerationGO:00311009.9ANGPT2, TEK
9positive regulation of focal adhesion assemblyGO:00518949.9TEK, VEGFA
10hemopoiesisGO:00300979.8ANGPT1, TEK
11Tie signaling pathwayGO:00480149.6ANGPT1, ANGPT2, TEK
12positive regulation of blood vessel endothelial cell migrationGO:00435369.6ANGPT1, VEGFA
13platelet degranulationGO:00025769.6PLG, VEGFA
14positive regulation of endothelial cell proliferationGO:00019389.6TEK, VEGFA
15positive regulation of receptor internalizationGO:00020929.6ANGPT1, VEGFA
16positive chemotaxisGO:00509189.5ANGPT1, VEGFA
17positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.4ANGPT1, VEGFA
18blood vessel morphogenesisGO:00485149.4ANGPT2, VEGFA
19leukocyte migrationGO:00509009.3ANGPT1, ANGPT2, TEK
20positive regulation of endothelial cell migrationGO:00105959.2ANGPT1, TEK, VEGFA
21positive regulation of peptidyl-serine phosphorylationGO:00331389.1ANGPT1, TEK, VEGFA
22positive regulation of angiogenesisGO:00457669.0ANGPT2, TEK, VEGFA
23positive regulation of cell adhesionGO:00457859.0ANGPT1, TEK, VEGFA
24response to hypoxiaGO:00016669.0ANGPT2, TEK, VEGFA
25positive regulation of ERK1 and ERK2 cascadeGO:00703748.9ANGPT1, TEK, VEGFA
26vascular endothelial growth factor receptor signaling pathwayGO:00480108.7ANGPT1, TEK, VEGFA
27angiogenesisGO:00015258.5ANGPT1, ANGPT2, TEK, VEGFA
28negative regulation of apoptotic processGO:00430668.5ACTC1, ANGPT1, TEK, VEGFA
29blood coagulationGO:00075967.6ANGPT1, ANGPT2, PLG, TEK, VEGFA

Molecular functions related to Pyogenic Granuloma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor tyrosine kinase bindingGO:00309719.3ANGPT1, ANGPT2
2receptor bindingGO:00051027.7ANGPT1, ANGPT2, PLG, VEGFA

Sources for Pyogenic Granuloma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet