MCID: QDR001
MIFTS: 43

Quadriplegia malady

Neuronal diseases category

Summaries for Quadriplegia

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63Wikipedia, 32MalaCards
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Wikipedia:63 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury to a human that... more...

MalaCards: Quadriplegia, also known as quadriplegia, unspecified, is related to spastic quadriplegia and pelizaeus-merzbacher disease. An important gene associated with Quadriplegia is PLP1 (proteolipid protein 1), and among its related pathways are Interaction between L1 and Ankyrins and Other glycan degradation. The compound l-fucose have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and lung.

Aliases & Classifications for Quadriplegia

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH, 39NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

quadriplegia 8 10 60
quadriplegia, unspecified 8
tetraplegias 44
tetraplegia 8


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Disease Ontology8 DOID:12835
ICD9CM27 344.00
MeSH34 D011782
SNOMED-CT56 155030003, 11538006
NCIt39 C50721
ICD1025 G82.5

Related Diseases for Quadriplegia

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to quadriplegia

Clinical Features for Quadriplegia

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Drugs & Therapeutics for Quadriplegia

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Quadriplegia

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Anatomical Context for Quadriplegia

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32MalaCards
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MalaCards organs/tissues related to Quadriplegia:

32
Spinal cord, Bone, Lung, Heart, Prostate, Myeloid, Testes, Skin, Thyroid, Cerebellum, Occipital lobe

Animal Models for Quadriplegia or affiliated genes

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Publications for Quadriplegia

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50PubMed
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Articles related to Quadriplegia:

(show top 50)    (show all 501)
idTitleAuthorsYear
1
Lithium toxicity precipitated by thyrotoxicosis due to silent thyroiditis: cardiac arrest, quadriplegia, and coma. (23206122)
2013
2
Quadriplegia after off-pump coronary artery bypass surgery: look before you place the neck in an extended position. (23507022)
2013
3
Ischemic stroke of the pyramidal decussation causing quadriplegia and anarthria. (21411338)
2012
4
Quadriplegia due to pachymeningitis, vasculitis and sepsis in a patient with rheumatoid arthritis: a case report. (21744755)
2011
5
Rehabilitation of the elbow extension with motor imagery in a patient with quadriplegia after tendon transfer. (20599055)
2010
6
A medico-legal review of cases involving quadriplegia following cervical spine surgery: Is there an argument for a no-fault compensation system? (20657685)
2010
7
Effect of nutritional support in children with spastic quadriplegia. (18940556)
2008
8
Progression of scoliosis in patients with spastic quadriplegia after the insertion of an intrathecal baclofen pump. (18007255)
2007
9
Quadriplegia and cerebellar hemorrhage in spontaneous intracranial hypotension. (16769965)
2006
10
Current thinking: return to play and transient quadriplegia. (15659276)
2005
11
Subacute painful quadriplegia and purpura. (14678939)
2003
12
Progressive cerebellocerebral atrophy: a new syndrome with microcephaly, mental retardation, and spastic quadriplegia. (12920088)
2003
13
Quadriplegia after upper extremity trauma: case report. (11038101)
2000
14
Dramatic development of quadriplegia in a young man while engaged in heavy manual labour: a post-traumatic spinal cord injury? (9849865)
1998
15
Delayed cortical blindness and recurrent quadriplegia after cervical trauma. (9884301)
1998
16
Healthy young man who developed high cervical cord infarction with quadriplegia and occipital lobe infarction with visual disturbance after lumbar disc surgery. (9055378)
1997
17
Bone density and other possible predictors of fracture risk in children and adolescents with spastic quadriplegia. (9183259)
1997
18
Tips and tricks: the hard way--ABCs of quadriplegia care. (8706429)
1996
19
Anejaculation in quadriplegia. (7668965)
1995
20
Transient traumatic quadriplegia in a 29-year-old man without predisposing anatomic lesion. (7487446)
1995
21
Candida mediastinitis and septic shock following occult esophageal perforation in a patient with posttraumatic quadriplegia. (7473984)
1995
22
Pregnancy and its outcome in quadriplegia due to Pott's spine. (9764872)
1995
23
Left ventricular mass and diastolic filling patterns in quadriplegia and implications for effects of normal aging on the heart. (7810508)
1995
24
Cervical spinal stenosis with cord neurapraxia and transient quadriplegia. (8614762)
1995
25
Effect of hosiery on skin temperature in spastic quadriplegia. A preliminary study. (8040808)
1994
26
Waist and neck enlargement after quadriplegia. (7869061)
1994
27
Drug-induced dystonia in a patient with C4 quadriplegia. Case report. (8476550)
1993
28
Quadriplegia--some problems and some modern solutions. (8243081)
1993
29
When life support is questioned early in the care of patients with cervical-level quadriplegia. (8421482)
1993
30
Mechanism of unexpected death in a patient with C2 quadriplegia ventilated by aid of a phrenic nerve stimulator. Brief report. (1739443)
1992
31
Isolated intramedullary spinal artery aneurysm presenting with quadriplegia. Case report. (1607957)
1992
32
Bronchial mucus hypersecretion in acute quadriplegia. Macromolecular yields and glycoconjugate composition. (2001077)
1991
33
Early diagnosis of spastic diplegia, spastic hemiplegia, and quadriplegia. (2816867)
1989
34
The individual with high quadriplegia. (2522191)
1989
35
Electrophrenic respiration in patients with high quadriplegia. (2710297)
1989
36
Paraplegia and quadriplegia after intrathecal chemotherapy. (3214264)
1988
37
Indomethacin, hypoglycemia, quadriplegia. (3662786)
1987
38
Delayed quadriplegia following decompressive cervical laminectomy. (3621969)
1987
39
Trampoline-induced quadriplegia. (3334026)
1987
40
Traumatic quadriplegia after minor trauma in the Klippel-Feil syndrome. (3424045)
1987
41
Assessment of cardiac and respiratory function during surgery on patients with acute quadriplegia. (3998833)
1985
42
Historical background and changing perspectives in surgical reconstruction of the upper limb in quadriplegia. (6726221)
1984
43
Thick filament degeneration in a case of acute quadriplegia. (6444666)
1980
44
Neurofibrillary degeneration in a case of quadriplegia and myoclonic movement. (217225)
1979
45
The Moberg deltoid-triceps replacement and key-pinch operations in quadriplegia: preliminary experiences. (608617)
1977
46
Quadriplegia in Larsen syndrome. (890112)
1977
47
Relationship between serum dopamine-beta-hydroxylase activity, catecholamine metabolism, and hemodynamic changes during paroxysmal hypertension in quadriplegia. (4430080)
1974
48
Ventilatory assistance in quadriplegia. (4582714)
1973
49
Quadriplegia in Japan: a study of 60 cases. (4696055)
1973
50
Car transfer technique of a patient with quadriplegia. (5787961)
1969

Genetic Variations for Quadriplegia

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Expression for genes affiliated with Quadriplegia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Quadriplegia

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Pathways for genes affiliated with Quadriplegia

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53Reactome, 29KEGG
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Pathways related to Quadriplegia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1SPTAN1, ANK3
210.1FUCA2, FUCA1

Compounds for genes affiliated with Quadriplegia

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44Novoseek, 24HMDB
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Compounds related to Quadriplegia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1l-fucose44 2411.1FUCA2, FUCA1

GO Terms for genes affiliated with Quadriplegia

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16Gene Ontology
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Cellular components related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lysosomeGO:0057649.9FUCA2, FUCA1, ANK3

Biological processes related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1fucose metabolic processGO:00600410.1FUCA2, FUCA1

Molecular functions related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transferase activityGO:01674010.2ELOVL4, MOCS2
2alpha-L-fucosidase activityGO:00456010.1FUCA2, FUCA1
3fucose bindingGO:04280610.0FUCA2, FUCA1
4spectrin bindingGO:0305079.8SPTAN1, ANK3

Products for genes affiliated with Quadriplegia

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  • Antibodies
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Sources for Quadriplegia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet