MCID: QDR001
MIFTS: 37

Quadriplegia malady

Neuronal diseases category

Summaries for Quadriplegia

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Wikipedia:63 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury to a human that... more...

MalaCards based summary: Quadriplegia, also known as quadriplegia, unspecified, is related to spastic quadriplegia and cerebral palsy. An important gene associated with Quadriplegia is ELOVL4 (ELOVL fatty acid elongase 4), and among its related pathways are Arginine and proline metabolism and NCAM signaling for neurite out-growth. The compounds fatty acid and Water have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and lung, and related mouse phenotype nervous system.

Aliases & Classifications for Quadriplegia

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Sources:
9Disease Ontology, 11DISEASES, 60UMLS, 43Novoseek, 55SNOMED-CT, 27ICD9CM, 33MeSH, 38NCIt, 25ICD10
See all sources

Quadriplegia, Aliases & Descriptions:

Name: Quadriplegia 9 11 60
Quadriplegia, Unspecified 9
 
Tetraplegias 43
Tetraplegia 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


External Ids:

Disease Ontology9 DOID:12835
ICD9CM27 344.00
MeSH33 D011782
SNOMED-CT55 11538006, 155030003
NCIt38 C50721
ICD1025 G82.5

Related Diseases for Quadriplegia

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Diseases related to Quadriplegia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 202)
idRelated DiseaseScoreTop Affiliating Genes
1spastic quadriplegia31.2PLP1, FUCA2
2cerebral palsy29.9ALDH3A2, PLP1, AP4M1
3cervicitis10.8
4spasticity10.7
5paraplegia10.5
6microcephaly with spastic quadriplegia10.3
7ichthyosis, spastic quadriplegia, and mental retardation10.3
8spinal cord injury10.3
9spinal stenosis10.2
10epidural abscess10.2
11cerebritis10.2
12meningitis10.2
13spastic quadriplegia retinitis pigmentosa mental retardation10.2
14pulmonary function10.2
15hypokalemia10.2
16myopathy10.2
17scoliosis10.2
18congenital ichthyosis, microcephalus, quadriplegia10.2
19rheumatoid arthritis10.1
20arthritis10.1
21klippel-feil syndrome10.1
22hemiplegia10.1
23hyperostosis10.1
24blindness10.1
25congenital ichthyosis - intellectual disability - spastic quadriplegia10.1
26pneumococcal meningitis10.1
27spastic paralysis, infantile onset ascending10.0
28proud syndrome10.0
29neurogenic bladder10.0
30spastic paraplegia 1610.0
31dysphagia10.0
32west nile virus10.0
33alternating hemiplegia of childhood 210.0
34pelizaeus-merzbacher disease10.0
35alternating hemiplegia of childhood10.0
36burns10.0
37diffuse idiopathic skeletal hyperostosis10.0
38spondylosis10.0
39microcephaly10.0
40polyarteritis nodosa10.0
41central pontine myelinolysis10.0
42cortical blindness10.0
43eclampsia10.0
44osteomyelitis10.0
45poliomyelitis10.0
46prostatitis10.0
47spondylitis10.0
48tuberculosis10.0
49osteochondroma10.0
50pseudoprogeria syndrome10.0

Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to quadriplegia

Symptoms for Quadriplegia

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Drugs & Therapeutics for Quadriplegia

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Drug clinical trials:

Search ClinicalTrials for Quadriplegia

Search NIH Clinical Center for Quadriplegia

Genetic Tests for Quadriplegia

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Anatomical Context for Quadriplegia

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MalaCards organs/tissues related to Quadriplegia:

31
Spinal cord, Bone, Lung, Heart, Prostate, Cerebellum, Thyroid, Skin, Testes, Myeloid, Occipital lobe

Animal Models for Quadriplegia or affiliated genes

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MGI Mouse Phenotypes related to Quadriplegia:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.7ARG1, ALDH3A2, PLP1, ELOVL4, TIAM1, ATP1A3

Publications for Quadriplegia

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Articles related to Quadriplegia:

(show top 50)    (show all 508)
idTitleAuthorsYear
1
Case 1: Transient quadriplegia in a teenager. (25414576)
2014
2
Quadriplegia after interscalene block for shoulder surgery in sitting position. (24108735)
2013
3
Hypokalemia-induced pseudoischemic electrocardiographic changes and quadriplegia. (24176583)
2013
4
Levofloxacin-associated hypoglycaemia complicated by pontine myelinolysis and quadriplegia. (18644072)
2008
5
Pressure necrosis masquerading as a burn injury in a patient with a cervical epidural abscess producing acute quadriplegia. (18535478)
2008
6
A cocaine-associated quadriplegia and motor aphasia after first use of cocaine. (17724897)
2007
7
Anaesthetic management of labour in a woman with quadriplegia and autonomic hyperreflexia. (15477069)
2004
8
Transient quadriplegia and return-to-play criteria. (15262379)
2004
9
Subacute painful quadriplegia and purpura. (14678939)
2003
10
Proximal femoral resection for subluxation or dislocation of the hip in spastic quadriplegia. (12828396)
2003
11
Quadriplegia in a patient who underwent posterior fossa surgery in the prone position. Case report. (11795695)
2002
12
Dialysis-related cervical amyloidoma presenting with quadriplegia. (11256523)
2001
13
Acute quadriplegia in a 34-year-old man. (11142462)
2000
14
Dramatic development of quadriplegia in a young man while engaged in heavy manual labour: a post-traumatic spinal cord injury? (9849865)
1998
15
Healthy young man who developed high cervical cord infarction with quadriplegia and occipital lobe infarction with visual disturbance after lumbar disc surgery. (9055378)
1997
16
The bionic glove: an electrical stimulator garment that provides controlled grasp and hand opening in quadriplegia. (9196468)
1997
17
Quadriplegia with cervical cord compression. (9246353)
1997
18
Increased energy needs in patients with quadriplegia and pressure ulcers. (8716273)
1996
19
Cervical spine meningioma causing acute-onset quadriplegia in an aged sheep. (7660560)
1995
20
Guidelines for return to contact sports after transient quadriplegia. (8113878)
1994
21
Chest tubes, lung entrapment, and failure to wean from the ventilator. Report of three patients with quadriplegia. (8162779)
1994
22
Tuberculosis of the odontoid bone: a rare but treatable cause of quadriplegia. (1596764)
1992
23
Quadriplegia. (2067446)
1991
24
Upper extremity inhibitive casting in a boy with spastic quadriplegia. (2353723)
1990
25
Functional electrical stimulation for upper limb strengthening in traumatic quadriplegia. (2789028)
1989
26
Pregnancy and quadriplegia: an occupational therapy home program. (2923173)
1989
27
Advances in surgical reconstruction of upper extremities in quadriplegia. (18750454)
1988
28
Biofeedback to facilitate unassisted ventilation in individuals with high-level quadriplegia. A case report. (3420172)
1988
29
Chiari I malformation with quadriplegia and respiratory disturbance in an infant. (3407857)
1988
30
Pneumatosis cystoides intestinalis in quadriplegia: a case report. (3632326)
1987
31
Indomethacin, hypoglycemia, quadriplegia. (3662786)
1987
32
Arteriovenous shunting in quadriplegia. (2946017)
1986
33
Quadriplegia, orthostatic hypotension, and phenelzine with tyramine. (4051358)
1985
34
External fixation in quadriplegia. (6705341)
1984
35
Depression of respiratory function by pneumatic antishock trousers in traumatic quadriplegia. (6859634)
1983
36
Paraplegia and quadriplegia in the elderly due to spinal cord lesions: association with malignancy. (7204805)
1981
37
Coping with quadriplegia. (6910986)
1981
38
Thick filament degeneration in a case of acute quadriplegia. (6444666)
1980
39
Functional exercise position for treating persons with quadriplegia. (7443794)
1980
40
Clinical implications of the disturbance in calcium and collagen metabolism in quadriplegia. (7203754)
1980
41
Osteochondroma of the cervical spine: a cause of transient quadriplegia. (460559)
1979
42
The avocational pursuits of rehabilitants with traumatic quadriplegia. (707253)
1978
43
Quadriplegia and cortical blindness in Hemophilus influenzae meningitis. (671161)
1978
44
Long-term ventilatory support by diaphragm pacing in quadriplegia. (1275596)
1976
45
Independent condom application for urinary drainage in C6 quadriplegia. (4842371)
1974
46
Electrophrenic respiration: a breathing support system in quadriplegia. (4837485)
1974
47
Car transfer technique of a patient with quadriplegia. (5787961)
1969
48
A temporary method of controlling orthostatic hypotension in quadriplegia. (5685055)
1968
49
Research in biological rhythms in quadriplegia. (5191695)
1967
50
The association of congenital spastic quadriplegia and androgenic precocity in four patients. (15436558)
1950

Variations for Quadriplegia

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Expression for genes affiliated with Quadriplegia

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Search GEO for disease gene expression data for Quadriplegia.

Pathways for genes affiliated with Quadriplegia

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Pathways related to Quadriplegia according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
citrulline-nitric oxide cycle36
arginine degradation I (arginase pathway)36
proline degradation36
glutamine degradation I36
proline biosynthesis I36
superpathway of citrulline metabolism36
proline biosynthesis II (from arginine)36
citrulline biosynthesis36
arginine degradation VI (arginase 2 pathway)36
Urea cycle and metabolism of amino groups36
asparagine biosynthesis I36
4-hydroxyproline degradation I36
citrulline degradation36
9.8ARG1, ALDH3A2
2
Show member pathways
9.7COL6A1, SPTAN1
39.6COL6A1, ATP1A3

Compounds for genes affiliated with Quadriplegia

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Sources:
43Novoseek, 24HMDB
See all sources

Compounds related to Quadriplegia according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1fatty acid439.6ALDH3A2, ELOVL4, PLP1
2Water248.7ATP1A3, FUCA2, ALDH3A2, ARG1
3glutamate438.4ARG1, SPTAN1, TIAM1, PLP1

GO Terms for genes affiliated with Quadriplegia

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Cellular components related to Quadriplegia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1myelin sheathGO:00432099.8PLP1, ATP1A3

Products for genes affiliated with Quadriplegia

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Sources for Quadriplegia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet