MCID: QDR001
MIFTS: 44

Quadriplegia malady

Neuronal diseases category
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Summaries for Quadriplegia

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Wikipedia:65 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury to a human that... more...

MalaCards based summary: Quadriplegia, also known as quadriplegia, unspecified, is related to spastic quadriplegia and cerebral palsy. An important gene associated with Quadriplegia is ELOVL4 (ELOVL fatty acid elongase 4), and among its related pathways are Arginine and proline metabolism and NCAM signaling for neurite out-growth. The compounds fatty acid and Water have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and lung, and related mouse phenotype nervous system.

Aliases & Classifications for Quadriplegia

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 57SNOMED-CT, 39NCIt, 34MeSH, 27ICD9CM, 25ICD10
See all sources

Quadriplegia, Aliases & Descriptions:

Name: Quadriplegia 8 10 62
Quadriplegia, Unspecified 8
 
Tetraplegias 44
Tetraplegia 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


External Ids:

Disease Ontology8 DOID:12835
NCIt39 C50721
MeSH34 D011782
SNOMED-CT57 11538006, 155030003
ICD9CM27 344.00
ICD1025 G82.5

Related Diseases for Quadriplegia

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Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to quadriplegia

Symptoms for Quadriplegia

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Drugs & Therapeutics for Quadriplegia

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Drug clinical trials:

Search ClinicalTrials for Quadriplegia

Search NIH Clinical Center for Quadriplegia

Genetic Tests for Quadriplegia

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Anatomical Context for Quadriplegia

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MalaCards organs/tissues related to Quadriplegia:

32
Spinal cord, Bone, Lung, Heart, Prostate, Cerebellum, Thyroid, Skin, Testes, Myeloid, Occipital lobe

Animal Models for Quadriplegia or affiliated genes

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MGI Mouse Phenotypes related to Quadriplegia:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.7ARG1, ALDH3A2, PLP1, ELOVL4, TIAM1, ATP1A3

Publications for Quadriplegia

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Articles related to Quadriplegia:

(show top 50)    (show all 502)
idTitleAuthorsYear
1
Quadriplegia after interscalene block for shoulder surgery in sitting position. (24108735)
2013
2
Hypokalemia-induced pseudoischemic electrocardiographic changes and quadriplegia. (24176583)
2013
3
Levofloxacin-associated hypoglycaemia complicated by pontine myelinolysis and quadriplegia. (18644072)
2008
4
Pressure necrosis masquerading as a burn injury in a patient with a cervical epidural abscess producing acute quadriplegia. (18535478)
2008
5
A cocaine-associated quadriplegia and motor aphasia after first use of cocaine. (17724897)
2007
6
Anaesthetic management of labour in a woman with quadriplegia and autonomic hyperreflexia. (15477069)
2004
7
Transient quadriplegia and return-to-play criteria. (15262379)
2004
8
Subacute painful quadriplegia and purpura. (14678939)
2003
9
Proximal femoral resection for subluxation or dislocation of the hip in spastic quadriplegia. (12828396)
2003
10
Quadriplegia in a patient who underwent posterior fossa surgery in the prone position. Case report. (11795695)
2002
11
Dialysis-related cervical amyloidoma presenting with quadriplegia. (11256523)
2001
12
Acute quadriplegia in a 34-year-old man. (11142462)
2000
13
Healthy young man who developed high cervical cord infarction with quadriplegia and occipital lobe infarction with visual disturbance after lumbar disc surgery. (9055378)
1997
14
The bionic glove: an electrical stimulator garment that provides controlled grasp and hand opening in quadriplegia. (9196468)
1997
15
Quadriplegia with cervical cord compression. (9246353)
1997
16
Increased energy needs in patients with quadriplegia and pressure ulcers. (8716273)
1996
17
Cervical spine meningioma causing acute-onset quadriplegia in an aged sheep. (7660560)
1995
18
Guidelines for return to contact sports after transient quadriplegia. (8113878)
1994
19
Chest tubes, lung entrapment, and failure to wean from the ventilator. Report of three patients with quadriplegia. (8162779)
1994
20
Tuberculosis of the odontoid bone: a rare but treatable cause of quadriplegia. (1596764)
1992
21
Quadriplegia. (2067446)
1991
22
Upper extremity inhibitive casting in a boy with spastic quadriplegia. (2353723)
1990
23
Functional electrical stimulation for upper limb strengthening in traumatic quadriplegia. (2789028)
1989
24
Pregnancy and quadriplegia: an occupational therapy home program. (2923173)
1989
25
Advances in surgical reconstruction of upper extremities in quadriplegia. (18750454)
1988
26
Biofeedback to facilitate unassisted ventilation in individuals with high-level quadriplegia. A case report. (3420172)
1988
27
Chiari I malformation with quadriplegia and respiratory disturbance in an infant. (3407857)
1988
28
Pneumatosis cystoides intestinalis in quadriplegia: a case report. (3632326)
1987
29
Indomethacin, hypoglycemia, quadriplegia. (3662786)
1987
30
Arteriovenous shunting in quadriplegia. (2946017)
1986
31
Quadriplegia, orthostatic hypotension, and phenelzine with tyramine. (4051358)
1985
32
External fixation in quadriplegia. (6705341)
1984
33
Depression of respiratory function by pneumatic antishock trousers in traumatic quadriplegia. (6859634)
1983
34
Hypothesis: the etiology of midcervical quadriplegia after operation with the patient in the sitting position. (7145069)
1982
35
Paraplegia and quadriplegia in the elderly due to spinal cord lesions: association with malignancy. (7204805)
1981
36
Coping with quadriplegia. (6910986)
1981
37
Thick filament degeneration in a case of acute quadriplegia. (6444666)
1980
38
Functional exercise position for treating persons with quadriplegia. (7443794)
1980
39
Clinical implications of the disturbance in calcium and collagen metabolism in quadriplegia. (7203754)
1980
40
Osteochondroma of the cervical spine: a cause of transient quadriplegia. (460559)
1979
41
The avocational pursuits of rehabilitants with traumatic quadriplegia. (707253)
1978
42
Quadriplegia and cortical blindness in Hemophilus influenzae meningitis. (671161)
1978
43
Steady state hormonal secretion in traumatic quadriplegia. (838851)
1977
44
Long-term ventilatory support by diaphragm pacing in quadriplegia. (1275596)
1976
45
Independent condom application for urinary drainage in C6 quadriplegia. (4842371)
1974
46
Electrophrenic respiration: a breathing support system in quadriplegia. (4837485)
1974
47
Car transfer technique of a patient with quadriplegia. (5787961)
1969
48
A temporary method of controlling orthostatic hypotension in quadriplegia. (5685055)
1968
49
Research in biological rhythms in quadriplegia. (5191695)
1967
50
The association of congenital spastic quadriplegia and androgenic precocity in four patients. (15436558)
1950

Variations for Quadriplegia

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Expression for genes affiliated with Quadriplegia

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Expression patterns in normal tissues for genes affiliated with Quadriplegia

Search GEO for disease gene expression data for Quadriplegia.

Pathways for genes affiliated with Quadriplegia

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Pathways related to Quadriplegia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
citrulline-nitric oxide cycle37
arginine degradation I (arginase pathway)37
proline degradation37
glutamine degradation I37
proline biosynthesis I37
superpathway of citrulline metabolism37
proline biosynthesis II (from arginine)37
citrulline biosynthesis37
arginine degradation VI (arginase 2 pathway)37
Urea cycle and metabolism of amino groups37
asparagine biosynthesis I37
4-hydroxyproline degradation I37
citrulline degradation37
9.8ARG1, ALDH3A2
2
Show member pathways
9.7COL6A1, SPTAN1
39.6COL6A1, ATP1A3

Compounds for genes affiliated with Quadriplegia

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Sources:
44Novoseek, 24HMDB
See all sources

Compounds related to Quadriplegia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1fatty acid449.6ALDH3A2, ELOVL4, PLP1
2Water248.7ATP1A3, FUCA2, ALDH3A2, ARG1
3glutamate448.4ARG1, SPTAN1, TIAM1, PLP1

GO Terms for genes affiliated with Quadriplegia

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Cellular components related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1myelin sheathGO:0432099.8PLP1, ATP1A3

Products for genes affiliated with Quadriplegia

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Sources for Quadriplegia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet