MCID: QDR001
MIFTS: 43

Quadriplegia malady

Neuronal diseases category

Summaries for Quadriplegia

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury to a human that... more...

MalaCards: Quadriplegia, also known as quadriplegia, unspecified, is related to spastic quadriplegia and pelizaeus-merzbacher disease. An important gene associated with Quadriplegia is PLP1 (proteolipid protein 1), and among its related pathways are Interaction between L1 and Ankyrins and Other glycan degradation. The compound l-fucose have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and lung.

Aliases & Classifications for Quadriplegia

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH, 39NCIt, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

quadriplegia 8 10 60
quadriplegia, unspecified 8
tetraplegias 44
tetraplegia 8


External Ids:

Disease Ontology8 DOID:12835
ICD9CM27 344.00
MeSH34 D011782
SNOMED-CT56 155030003, 11538006
NCIt39 C50721
ICD1025 G82.5

Related Diseases for Quadriplegia

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to quadriplegia

Clinical Features for Quadriplegia

About this section

Drugs & Therapeutics for Quadriplegia

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Quadriplegia

Drug clinical trials:

Search ClinicalTrials for Quadriplegia

Search NIH Clinical Center for Quadriplegia

Search CenterWatch for Quadriplegia

Genetic Tests for Quadriplegia

About this section

Anatomical Context for Quadriplegia

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Quadriplegia:

32
Spinal cord, Bone, Lung, Heart, Prostate, Myeloid, Testes, Skin, Thyroid, Cerebellum, Occipital lobe

Animal Models for Quadriplegia or affiliated genes

About this section

Publications for Quadriplegia

About this section
Sources:
50PubMed
See all sources

Articles related to Quadriplegia:

(show top 50)    (show all 501)
idTitleAuthorsYear
1
Successful weaning from mechanical ventilation in the quadriplegia patient with C2 spinal cord injury undergoing C2-4 spine laminoplasty -A case report-. (23814658)
2013
2
Quadriplegia due to celiac crisis with hypokalemia as initial presentation of celiac disease: a case report. (21525142)
2012
3
The terms diplegia, quadriplegia, and hemiplegia should be phased out. (20846158)
2010
4
Pressure necrosis masquerading as a burn injury in a patient with a cervical epidural abscess producing acute quadriplegia. (18535478)
2008
5
Acute painless progressive quadriplegia associated with warfarin use. (17493205)
2007
6
A case of hearing loss and quadriplegia after a pontine hemorrhage. (16297409)
2006
7
Direct percutaneous intratumoral bleomycin injection for palliative treatment of impending quadriplegia. (15205162)
2004
8
Quadriplegia in a 10 year-old boy due to multiple cervical neurofibromas. (12973159)
2003
9
Acute quadriplegia and loss of muscle myosin in patients treated with nondepolarizing neuromuscular blocking agents and corticosteroids: mechanisms at the cellular and molecular levels. (10667496)
2000
10
Quadriplegia caused by cervical hyperextension injury and intramedullary spinal cord tumour: a case report of autopsy. (9813683)
1998
11
Cervical spine injury - quadriplegia. (9616058)
1998
12
Hypokalemic quadriplegia and rhabdomyolysis in a HIV-positive patient. (9434934)
1997
13
Increased energy needs in patients with quadriplegia and pressure ulcers. (8716273)
1996
14
Sleep apnoea in patients with quadriplegia. (7638801)
1995
15
Acute quadriplegia as a presenting symptom of acute myeloid leukemia. (10829956)
1995
16
Cervical spine injury--quadriplegia. (7830416)
1994
17
Life support for patients with cervical-level quadriplegia. (8341350)
1993
18
Life support for cervical-level quadriplegia questioned. (10129495)
1993
19
Assessing selfcare status in quadriplegia: comparison of the quadriplegia index of function (QIF) and the functional independence measure (FIM). (8493037)
1993
20
Hand splinting in quadriplegia: current practice. (1595826)
1992
21
Oxygen cost of resistive-loaded breathing in quadriplegia. (1400044)
1992
22
Acute quadriplegia in acromegaly. (1596060)
1992
23
Superior mesenteric artery syndrome in acute traumatic quadriplegia: case reports and literature review. (2059111)
1991
24
Functional electrical stimulation for upper limb strengthening in traumatic quadriplegia. (2789028)
1989
25
Chiari I malformation with quadriplegia and respiratory disturbance in an infant. (3407857)
1988
26
Atlantoaxial dislocation presenting as sudden onset of quadriplegia in Down's syndrome. (2969628)
1988
27
Cervical spinal stenosis with cord neurapraxia and transient quadriplegia. (3334023)
1987
28
Neurapraxia of the cervical spinal cord with transient quadriplegia. (3597489)
1987
29
Recovery of nerve root function after complete quadriplegia from cervical spine fractures. (3785630)
1986
30
Changes in lung volume and rib cage configuration with abdominal binding in quadriplegia. (3700303)
1986
31
Pediatric management problems (quadriplegia). (3635831)
1986
32
General metabolism in patients with acute paraplegia and quadriplegia. (3982608)
1985
33
Quadriplegia associated with cervical deformity in a lamb. (6710837)
1984
34
Quadriplegia following rugby football injury. (6707623)
1984
35
Hypotension associated with terbutaline therapy in acute quadriplegia--a report of two cases. (7125369)
1982
36
Clinical implications of the disturbance in calcium and collagen metabolism in quadriplegia. (7203754)
1980
37
Traumatic quadriplegia: follow-up study of self-care skills. (7396683)
1980
38
Maternal quadriplegia complicating pregnancy: report of case. (7429898)
1980
39
Urological disability in quadriplegia: a study of treatment and follow-up in 92 patients. (7459577)
1980
40
The avocational pursuits of rehabilitants with traumatic quadriplegia. (707253)
1978
41
Immediate endocrine and metabolic consequences of traumatic quadriplegia in a young woman. (201901)
1977
42
Urinary excretion of glycosaminoglycans in quadriplegia. (594079)
1977
43
Treatment of a patient with a complete C1 quadriplegia. (1088990)
1975
44
Corrective therapy in the rehabilitation of the quadriplegia patient. (4851194)
1974
45
Oral-facial dyskinesia and quadriplegia associated with poliomyelitis virus type 3. (4355448)
1973
46
Calcium excretion in quadriplegia. (5007657)
1972
47
Our method of treatment of traumatic quadriplegia. (5161647)
1971
48
Hyperkalemic quadriplegia in Addison's disease without hyperpigmentation. (5490979)
1970
49
The effect of inhalation of 5 per cent carbon dioxide in air on postural hypotension in quadriplegia. (4952410)
1966
50
The association of congenital spastic quadriplegia and androgenic precocity in four patients. (15436558)
1950

Genetic Variations for Quadriplegia

About this section

Expression for genes affiliated with Quadriplegia

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Quadriplegia

Search GEO for disease gene expression data for Quadriplegia.

Pathways for genes affiliated with Quadriplegia

About this section
Sources:
53Reactome, 29KEGG
See all sources

Pathways related to Quadriplegia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1SPTAN1, ANK3
210.1FUCA2, FUCA1

Compounds for genes affiliated with Quadriplegia

About this section
Sources:
44Novoseek, 24HMDB
See all sources

Compounds related to Quadriplegia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1l-fucose44 2411.1FUCA2, FUCA1

GO Terms for genes affiliated with Quadriplegia

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lysosomeGO:0057649.9FUCA2, FUCA1, ANK3

Biological processes related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1fucose metabolic processGO:00600410.1FUCA2, FUCA1

Molecular functions related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transferase activityGO:01674010.2ELOVL4, MOCS2
2alpha-L-fucosidase activityGO:00456010.1FUCA2, FUCA1
3fucose bindingGO:04280610.0FUCA2, FUCA1
4spectrin bindingGO:0305079.8SPTAN1, ANK3

Products for genes affiliated with Quadriplegia

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Quadriplegia

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet