MCID: QDR001
MIFTS: 43

Quadriplegia malady

Neuronal diseases category

Summaries for Quadriplegia

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66Wikipedia, 34MalaCards
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Wikipedia:66 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury to a human that... more...

MalaCards: Quadriplegia, also known as quadriplegia, unspecified, is related to spastic quadriplegia and cerebral palsy. An important gene associated with Quadriplegia is ELOVL4 (ELOVL fatty acid elongase 4), and among its related pathways are Arginine and proline metabolism and NCAM signaling for neurite out-growth. The compounds fatty acid and Water have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and lung, and related mouse phenotype nervous system.

Aliases & Classifications for Quadriplegia

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9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 41NCIt, 28ICD9CM, 36MeSH, 59SNOMED-CT, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

quadriplegia 9 11 63
quadriplegia, unspecified 9
tetraplegias 46
tetraplegia 9


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Disease Ontology9 DOID:12835
NCIt41 C50721
ICD9CM28 344.00
SNOMED-CT59 11538006, 155030003
MeSH36 D011782
ICD1026 G82.5

Related Diseases for Quadriplegia

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to quadriplegia

Symptoms for Quadriplegia

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Drugs & Therapeutics for Quadriplegia

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Quadriplegia

Search NIH Clinical Center for Quadriplegia

Search CenterWatch for Quadriplegia

Genetic Tests for Quadriplegia

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Anatomical Context for Quadriplegia

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34MalaCards
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MalaCards organs/tissues related to Quadriplegia:

34
Spinal cord, Bone, Lung, Heart, Prostate, Myeloid, Testes, Skin, Thyroid, Cerebellum, Occipital lobe

Animal Models for Quadriplegia or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Quadriplegia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.7ARG1, ALDH3A2, PLP1, ELOVL4, TIAM1, ATP1A3

Publications for Quadriplegia

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53PubMed
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Articles related to Quadriplegia:

(show top 50)    (show all 499)
idTitleAuthorsYear
1
Quadriplegia after interscalene block for shoulder surgery in sitting position. (24108735)
2013
2
Hypokalemia-induced pseudoischemic electrocardiographic changes and quadriplegia. (24176583)
2013
3
Levofloxacin-associated hypoglycaemia complicated by pontine myelinolysis and quadriplegia. (18644072)
2008
4
Pressure necrosis masquerading as a burn injury in a patient with a cervical epidural abscess producing acute quadriplegia. (18535478)
2008
5
A cocaine-associated quadriplegia and motor aphasia after first use of cocaine. (17724897)
2007
6
Anaesthetic management of labour in a woman with quadriplegia and autonomic hyperreflexia. (15477069)
2004
7
Transient quadriplegia and return-to-play criteria. (15262379)
2004
8
Subacute painful quadriplegia and purpura. (14678939)
2003
9
Proximal femoral resection for subluxation or dislocation of the hip in spastic quadriplegia. (12828396)
2003
10
Quadriplegia in a patient who underwent posterior fossa surgery in the prone position. Case report. (11795695)
2002
11
Dialysis-related cervical amyloidoma presenting with quadriplegia. (11256523)
2001
12
Acute quadriplegia in a 34-year-old man. (11142462)
2000
13
Dramatic development of quadriplegia in a young man while engaged in heavy manual labour: a post-traumatic spinal cord injury? (9849865)
1998
14
Healthy young man who developed high cervical cord infarction with quadriplegia and occipital lobe infarction with visual disturbance after lumbar disc surgery. (9055378)
1997
15
The bionic glove: an electrical stimulator garment that provides controlled grasp and hand opening in quadriplegia. (9196468)
1997
16
Quadriplegia with cervical cord compression. (9246353)
1997
17
Increased energy needs in patients with quadriplegia and pressure ulcers. (8716273)
1996
18
Cervical spine meningioma causing acute-onset quadriplegia in an aged sheep. (7660560)
1995
19
Guidelines for return to contact sports after transient quadriplegia. (8113878)
1994
20
Chest tubes, lung entrapment, and failure to wean from the ventilator. Report of three patients with quadriplegia. (8162779)
1994
21
Tuberculosis of the odontoid bone: a rare but treatable cause of quadriplegia. (1596764)
1992
22
Quadriplegia. (2067446)
1991
23
Upper extremity inhibitive casting in a boy with spastic quadriplegia. (2353723)
1990
24
Functional electrical stimulation for upper limb strengthening in traumatic quadriplegia. (2789028)
1989
25
Pregnancy and quadriplegia: an occupational therapy home program. (2923173)
1989
26
Advances in surgical reconstruction of upper extremities in quadriplegia. (18750454)
1988
27
Biofeedback to facilitate unassisted ventilation in individuals with high-level quadriplegia. A case report. (3420172)
1988
28
Chiari I malformation with quadriplegia and respiratory disturbance in an infant. (3407857)
1988
29
Pneumatosis cystoides intestinalis in quadriplegia: a case report. (3632326)
1987
30
Indomethacin, hypoglycemia, quadriplegia. (3662786)
1987
31
Arteriovenous shunting in quadriplegia. (2946017)
1986
32
Quadriplegia, orthostatic hypotension, and phenelzine with tyramine. (4051358)
1985
33
External fixation in quadriplegia. (6705341)
1984
34
Depression of respiratory function by pneumatic antishock trousers in traumatic quadriplegia. (6859634)
1983
35
Paraplegia and quadriplegia in the elderly due to spinal cord lesions: association with malignancy. (7204805)
1981
36
Coping with quadriplegia. (6910986)
1981
37
Thick filament degeneration in a case of acute quadriplegia. (6444666)
1980
38
Functional exercise position for treating persons with quadriplegia. (7443794)
1980
39
Clinical implications of the disturbance in calcium and collagen metabolism in quadriplegia. (7203754)
1980
40
Osteochondroma of the cervical spine: a cause of transient quadriplegia. (460559)
1979
41
The avocational pursuits of rehabilitants with traumatic quadriplegia. (707253)
1978
42
Quadriplegia and cortical blindness in Hemophilus influenzae meningitis. (671161)
1978
43
Steady state hormonal secretion in traumatic quadriplegia. (838851)
1977
44
Long-term ventilatory support by diaphragm pacing in quadriplegia. (1275596)
1976
45
Independent condom application for urinary drainage in C6 quadriplegia. (4842371)
1974
46
Electrophrenic respiration: a breathing support system in quadriplegia. (4837485)
1974
47
Car transfer technique of a patient with quadriplegia. (5787961)
1969
48
A temporary method of controlling orthostatic hypotension in quadriplegia. (5685055)
1968
49
Research in biological rhythms in quadriplegia. (5191695)
1967
50
The association of congenital spastic quadriplegia and androgenic precocity in four patients. (15436558)
1950

Variations for Quadriplegia

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Expression for genes affiliated with Quadriplegia

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Quadriplegia

Search GEO for disease gene expression data for Quadriplegia.

Pathways for genes affiliated with Quadriplegia

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51PathCards, 31KEGG, 56Reactome, 39NCBI BioSystems Database
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Pathways related to Quadriplegia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
citrulline-nitric oxide cycle39
arginine degradation I (arginase pathway)39
proline degradation39
glutamine degradation I39
proline biosynthesis I39
superpathway of citrulline metabolism39
proline biosynthesis II (from arginine)39
citrulline biosynthesis39
arginine degradation VI (arginase 2 pathway)39
Urea cycle and metabolism of amino groups39
asparagine biosynthesis I39
4-hydroxyproline degradation I39
citrulline degradation39
9.8ARG1, ALDH3A2
2
Show member pathways
9.7COL6A1, SPTAN1
39.6COL6A1, ATP1A3

Compounds for genes affiliated with Quadriplegia

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46Novoseek, 25HMDB
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Compounds related to Quadriplegia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1fatty acid469.6ALDH3A2, PLP1, ELOVL4
2Water258.7ARG1, ALDH3A2, FUCA2, ATP1A3
3glutamate468.4SPTAN1, TIAM1, PLP1, ARG1

GO Terms for genes affiliated with Quadriplegia

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17Gene Ontology
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Cellular components related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1myelin sheathGO:0432099.8PLP1, ATP1A3

Products for genes affiliated with Quadriplegia

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  • Antibodies
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Sources for Quadriplegia

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet