MCID: QDR001
MIFTS: 42

Quadriplegia malady

Neuronal category

Summaries for Quadriplegia

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury to a human that... more...

MalaCards: Quadriplegia, also known as quadriplegia, unspecified, is related to spastic quadriplegia and mental retardation. An important gene associated with Quadriplegia is PLP1 (proteolipid protein 1), and among its related pathways are Interaction between L1 and Ankyrins and Other glycan degradation. The compound l-fucose have been mentioned in the context of this disorder. Affiliated tissues include cerebellum, spinal cord and heart.

Aliases & Classifications for Quadriplegia

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 45Novoseek, 57SNOMED-CT, 27ICD9CM, 35MeSH, 40NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal


Aliases & Descriptions:

quadriplegia 8 10 61
quadriplegia, unspecified 8
tetraplegias 45
tetraplegia 8


External Ids:

Disease Ontology8 DOID:12835
ICD9CM27 344.00
MeSH35 D011782
SNOMED-CT57 155030003, 11538006
NCIt40 C50721
ICD1025 G82.5

Related Diseases for Quadriplegia

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to quadriplegia

Clinical Features for Quadriplegia

Drugs & Therapeutics for Quadriplegia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Quadriplegia

Search CenterWatch for Quadriplegia

Genetic Tests for Quadriplegia

Anatomical Context for Quadriplegia

Sources:
33MalaCards
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MalaCards organs/tissues related to Quadriplegia:

33
Cerebellum, Spinal cord, Heart, Skeletal muscle, Lung, Thyroid, Skin, Prostate, Myeloid, Occipital lobe, Fetal lung, Fetal thyroid

Animal Models for Quadriplegia or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Quadriplegia

Sources:
51PubMed
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Articles related to Quadriplegia:

(show top 50)    (show all 501)
idTitleAuthorsYear
1
From ileostomy to sudden quadriplegia with electrocardiographic abnormalities: a short and unfortunate path. (23064783)
2013
2
Spastic quadriplegia in Down syndrome with congenital duodenal stenosis/atresia. (22639992)
2012
3
The terms diplegia and quadriplegia should not be abandoned. (20030685)
2010
4
Intramedullary spinal immature teratoma: resolution of quadriplegia following resection in a 4-week-old infant. (21121736)
2010
5
Dominant-negative mutations in alpha-II spectrin cause West syndrome with severe cerebral hypomyelination, spastic quadriplegia, and developmental delay. (20493457)
2010
6
Relationship between median nerve somatosensory evoked potentials and spinal cord injury levels in patients with quadriplegia. (19153589)
2009
7
Osteoradionecrosis of the cervical spine presenting with quadriplegia in a patient previously treated with radiotherapy for laryngeal cancer: a case report. (19830155)
2009
8
Phrenic nerve neurotization utilizing the spinal accessory nerve: technical note with potential application in patients with high cervical quadriplegia. (18536924)
2008
9
Quadriplegia due to lead-contaminated opium--case report. (18942257)
2008
10
A case of acute quadriplegia complicating Mediterranean spotted fever. (17382465)
2007
11
Pneumorrhachis presenting as quadriplegia following surgery in the prone position. (17098730)
2006
12
Dialysis-related cervical amyloidoma presenting with quadriplegia. (11256523)
2001
13
A comparison of two functional tests in quadriplegia: the quadriplegia index of function and the functional independence measure. (9881732)
1998
14
Perception of the impact of assistive devices on daily life of three individuals with quadriplegia. (10159862)
1995
15
Status of the major epicardial coronary arteries at necropsy in paraplegia and quadriplegia. (8296746)
1994
16
Two methods of weaning persons with quadriplegia from mechanical ventilators. (8015852)
1994
17
Selective intrathecal phenol block to improve activities of daily living in patients with spastic quadriplegia. A preliminary report. (7970851)
1994
18
Quadriplegia: focus on rehabilitation. (8274393)
1993
19
Life support for patients with cervical-level quadriplegia. (8341348)
1993
20
Sensory root level recovery in patients with Frankel A quadriplegia. (1622315)
1992
21
A comparison of two breathing exercise programs for patients with quadriplegia. (1409873)
1992
22
Respiratory problems in patients with high lesion quadriplegia. (1601568)
1992
23
Candida pyelonephritis complicating traumatic C5 quadriplegia: diagnosis and management. (1998462)
1991
24
Quadriplegia in a patient with cervical spondylosis after thoracolumbar surgery in the prone position. (1888059)
1991
25
Neurologic recovery in quadriplegia following operative treatment. (2134435)
1990
26
Upper extremity assistive devices: assessment of use by spinal cord-injured patients with quadriplegia. (2178440)
1990
27
Electromyographic analysis of brachioradialis to flexor pollicis longus tendon transfer in quadriplegia. (2324467)
1990
28
Lumbar discitis in a patient with quadriplegia: case report. (2647058)
1989
29
Third International Conference on Surgical Rehabilitation of the Upper Limb in Tetraplegia (quadriplegia). (2584649)
1989
30
Biofeedback to facilitate unassisted ventilation in individuals with high-level quadriplegia. A case report. (3420172)
1988
31
Occupational therapy management of tendon transfers in persons with spinal cord injury quadriplegia. (23930963)
1988
32
Transient traumatic quadriplegia. (2882243)
1987
33
Arteriovenous shunting in quadriplegia. (2946017)
1986
34
Assessing sexual functions of the adult with traumatic quadriplegia. (2936839)
1986
35
Quadriplegia, orthostatic hypotension, and phenelzine with tyramine. (4051358)
1985
36
Sudden quadriplegia after a minor trauma. The role of preexisting spinal stenosis. (3966211)
1985
37
Enhancement of two motor functions of the lower extremity in a child with spastic quadriplegia. (3966079)
1985
38
Posttraumatic cystic myelopathy in motor incomplete quadriplegia presenting as progressive orthostasis. (6691795)
1984
39
Hypothesis: the etiology of midcervical quadriplegia after operation with the patient in the sitting position. (7145069)
1982
40
Reversible quadriplegia in a patient with giant-cell arteritis. (7089794)
1982
41
Skid loader modification for a man having C5-spared quadriplegia. (7138273)
1982
42
Acute quadriplegia due to bilateral cerebral metastases. (7193827)
1981
43
Traumatic quadriplegia associated with Klippel-Feil syndrome: discussion and case reports. (1156129)
1975
44
Surgical treatment for absent single-hand grip and elbow extension in quadriplegia. Principles and preliminary experience. (1112846)
1975
45
Independent condom application for urinary drainage in C6 quadriplegia. (4842371)
1974
46
Electrophrenic respiration: a breathing support system in quadriplegia. (4837485)
1974
47
Electrophrenic respiration in quadriplegia. (4809385)
1974
48
Effectiveness of functional retraining for patients with quadriplegia. (5101679)
1971
49
Traumatic quadriplegia with ectopic ossification. (4994178)
1971
50
Analysis of daily rhythms of adrenal function in men with quadriplegia due to spinal cord section. (5782144)
1969

Genetic Variations for Quadriplegia

Expression for genes affiliated with Quadriplegia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Quadriplegia

Search GEO for disease gene expression data for Quadriplegia.

Pathways for genes affiliated with Quadriplegia

Sources:
54Reactome, 30KEGG
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Pathways related to Quadriplegia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1SPTAN1, ANK3
210.1FUCA2, FUCA1

Compounds for genes affiliated with Quadriplegia

Sources:
45Novoseek, 24HMDB
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Compounds related to Quadriplegia according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1l-fucose45 2411.1FUCA2, FUCA1

GO Terms for genes affiliated with Quadriplegia

Sources:
16Gene Ontology
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Cellular components related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lysosomeGO:0057649.9FUCA2, FUCA1, ANK3

Biological processes related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1fucose metabolic processGO:00600410.1FUCA2, FUCA1

Molecular functions related to Quadriplegia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transferase activityGO:01674010.2ELOVL4, MOCS2
2alpha-L-fucosidase activityGO:00456010.1FUCA2, FUCA1
3fucose bindingGO:04280610.0FUCA2, FUCA1
4spectrin bindingGO:0305079.8SPTAN1, ANK3

Products for genes affiliated with Quadriplegia

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  • Lysates
  • Antibodies

Sources for Quadriplegia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet