Aliases & Classifications for Quadriplegia

MalaCards integrated aliases for Quadriplegia:

Name: Quadriplegia 12 72 14 69
Tetraplegia 12 28
Tetraplegias 51

Classifications:



External Ids:

Disease Ontology 12 DOID:12835
ICD10 32 G82.5 G82.50
ICD9CM 34 344.00
MeSH 41 D011782
NCIt 46 C50721
SNOMED-CT 64 11538006 155030003
UMLS 69 C0034372

Summaries for Quadriplegia

MalaCards based summary : Quadriplegia, also known as tetraplegia, is related to spastic quadriplegia and pelizaeus-merzbacher disease, and has symptoms including other quadriplegia, quadriparesis and muscle weakness. An important gene associated with Quadriplegia is ALDH3A2 (Aldehyde Dehydrogenase 3 Family Member A2), and among its related pathways/superpathways are Endocrine and other factor-regulated calcium reabsorption and Carbohydrate digestion and absorption. The drugs Baclofen and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and bone, and related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 72 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury that results in the... more...

Related Diseases for Quadriplegia

Diseases related to Quadriplegia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 184)
# Related Disease Score Top Affiliating Genes
1 spastic quadriplegia 32.0 ELOVL4 KANK1 PLP1 SDHD SLC16A2 SPTAN1
2 pelizaeus-merzbacher disease 31.7 PLP1 SLC16A2
3 mitochondrial complex ii deficiency 31.2 SDHA SDHD
4 hemiplegia 29.3 ATP1A2 ATP1A3
5 ichthyosis, spastic quadriplegia, and mental retardation 12.3
6 spastic quadriplegia, retinitis pigmentosa, and mental retardation 11.9
7 microcephaly with spastic quadriplegia 11.9
8 congenital ichthyosis, microcephalus, quadriplegia 11.8
9 absent eyebrows and eyelashes with mental retardation 11.4
10 paraplegia 11.2
11 spinal cord injury 11.2
12 locked-in syndrome 11.0
13 alternating hemiplegia of childhood 1 11.0
14 alternating hemiplegia of childhood 2 11.0
15 microcephaly, seizures, spasticity, and brain calcifications 10.8
16 spastic tetraplegia, thin corpus callosum, and progressive microcephaly 10.8
17 spastic tetraplegia-retinitis pigmentosa-intellectual disability syndrome 10.8
18 spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome 10.8
19 congenital ichthyosis-microcephalus-tetraplegia syndrome 10.8
20 inherited congenital spastic tetraplegia 10.8
21 porphyria variegata 10.8
22 argininemia 10.8
23 allan-herndon-dudley syndrome 10.8
24 cerebral palsy, spastic quadriplegic, 2 10.8
25 epileptic encephalopathy, early infantile, 5 10.8
26 encephalopathy, progressive, early-onset, with brain atrophy and thin corpus callosum 10.8
27 immunodeficiency 49 10.8
28 epileptic encephalopathy, early infantile, 53 10.8
29 stxbp1 encephalopathy with epilepsy 10.8
30 encephalocele 10.8
31 familial glucocorticoid deficiency 10.8
32 cervicitis 10.5
33 spasticity 10.4
34 pelizaeus-merzbacher-like disease 10.2 PLP1 SLC16A2
35 neural crest tumor 10.2 SDHA SDHD
36 carney triad 10.2 SDHA SDHD
37 persistent generalized lymphadenopathy 10.1 SDHA SDHD
38 hereditary paraganglioma-pheochromocytoma syndromes 10.1 SDHA SDHD
39 lymph node disease 10.1 SDHA SDHD
40 familial hemiplegic migraine 10.1 ATP1A2 ATP1A3
41 hemiplegic migraine 10.0 ATP1A2 ATP1A3
42 cerebritis 10.0
43 epidural abscess 9.9
44 arthritis 9.9
45 cerebral palsy 9.9
46 spinal stenosis 9.9
47 meningitis 9.9
48 rheumatoid arthritis 9.9
49 aging 9.9
50 episodic pain syndrome, familial, 1 9.9

Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to Quadriplegia

Symptoms & Phenotypes for Quadriplegia

UMLS symptoms related to Quadriplegia:


other quadriplegia, quadriparesis, muscle weakness, ophthalmoplegia, hemiplegia

MGI Mouse Phenotypes related to Quadriplegia:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.86 SDHD ALDH3A2 ATP1A2 ATP1A3 BCL11B ELOVL4
2 homeostasis/metabolism MP:0005376 9.85 ALDH3A2 ATP1A2 ATP1A3 BCL11B ELOVL4 PIK3C2A
3 mortality/aging MP:0010768 9.61 ATP1A2 ATP1A3 BCL11B ELOVL4 PIK3C2A PLP1
4 nervous system MP:0003631 9.28 ALDH3A2 ATP1A2 ATP1A3 ELOVL4 PIK3C2A PLP1

Drugs & Therapeutics for Quadriplegia

Drugs for Quadriplegia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 86)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Baclofen Approved Phase 4 1134-47-0 2284
2
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
3
Midodrine Approved Phase 4,Phase 2 42794-76-3, 133163-28-7 4195
4
Acetylcholine Approved Phase 4 51-84-3 187
5
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
6 tannic acid Approved, Nutraceutical Phase 4
7
Melatonin Approved, Nutraceutical, Vet_approved Phase 4,Phase 1 73-31-4 896
8 Adrenergic Agents Phase 4,Phase 2,Phase 1
9 Adrenergic Agonists Phase 4,Phase 2,Phase 1
10 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1
11 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Phase 1
12 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1
13 Cholinergic Agents Phase 4,Phase 2,Phase 1
14 Adrenergic alpha-Agonists Phase 4,Phase 2
15 Vasoconstrictor Agents Phase 4,Phase 2
16 Antioxidants Phase 4,Phase 2,Phase 3,Phase 1
17 Central Nervous System Depressants Phase 4,Phase 1,Phase 2
18 Protective Agents Phase 4,Phase 2,Phase 3,Phase 1
19 abobotulinumtoxinA Phase 4
20 Botulinum Toxins Phase 4
21 Botulinum Toxins, Type A Phase 4
22 Neuromuscular Agents Phase 4
23 onabotulinumtoxinA Phase 4
24 Phosphodiesterase 5 Inhibitors Phase 4
25 Phosphodiesterase Inhibitors Phase 4
26 Vasodilator Agents Phase 4,Phase 2,Phase 3
27 Anesthetics Phase 4,Phase 1
28 Anesthetics, General Phase 4
29 Omega 3 Fatty Acid Nutraceutical Phase 4
30
Nitric Oxide Approved Phase 2, Phase 3, Phase 1 10102-43-9 145068
31
Menthol Approved Phase 2, Phase 3 2216-51-5 16666
32
Fenofibrate Approved Phase 2, Phase 3 49562-28-9 3339
33 Anti-Asthmatic Agents Phase 2, Phase 3, Phase 1
34 Bronchodilator Agents Phase 2, Phase 3, Phase 1
35 Respiratory System Agents Phase 2, Phase 3, Phase 1
36 Endothelium-Dependent Relaxing Factors Phase 2, Phase 3
37 NG-Nitroarginine Methyl Ester Phase 2, Phase 3
38 Fibrin Tissue Adhesive Phase 2, Phase 3,Phase 1
39 Hemostatics Phase 2, Phase 3,Phase 1
40 Antimetabolites Phase 2, Phase 3
41 Hypolipidemic Agents Phase 2, Phase 3
42 Lipid Regulating Agents Phase 2, Phase 3
43 arginine Nutraceutical Phase 2, Phase 3
44
Buspirone Approved, Investigational Phase 1, Phase 2 36505-84-7 2477
45
Carbidopa Approved Phase 1, Phase 2 28860-95-9 38101 34359
46
Dopamine Approved Phase 1, Phase 2 51-61-6, 62-31-7 681
47
Levodopa Approved Phase 1, Phase 2 59-92-7 6047
48
Nitroarginine Experimental, Investigational Phase 2 2149-70-4
49 Bromides Phase 2,Phase 1
50 Cholinergic Antagonists Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 122)

# Name Status NCT ID Phase Drugs
1 Eyegaze Systems for Spinal Cord Injury: A Feasibility Study Unknown status NCT01943656 Phase 4
2 Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes? Unknown status NCT00752934 Phase 4 oral baclofen + placebo;placebo + oral baclofen
3 Body Temperature in Persons With Tetraplegia When Exposed to Cold Completed NCT01822535 Phase 4 Midodrine hydrochloride
4 Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels Completed NCT01896037 Phase 4
5 Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia Completed NCT00507546 Phase 4 Ramelteon;Placebo
6 Diaphragmatic Reinnervation of Tetraplegic Patients With Respiratory Insufficiency Completed NCT01350297 Phase 4
7 Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury. Completed NCT00320281 Phase 4 botulinum toxin A
8 Effect of Tadalafil (Cialis) on the Cardiovascular System of Spinal Cord Injury (SCI) Males Completed NCT01067391 Phase 4 tadalafil;placebo
9 Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia Recruiting NCT02379156 Phase 4 Midodrine Hydrochloride
10 Nerve Transfer Reconstruction in the Tetraplegic Upper Extremity Recruiting NCT01579604 Phase 4
11 SCIPA (Spinal Cord Injury and Physical Activity) Hands-On: Early Intensive Hand Rehabilitation After Spinal Cord Injury Unknown status NCT01086930 Phase 3
12 Retraining Walking After Spinal Cord Injury Unknown status NCT00059553 Phase 2, Phase 3
13 Exhaled Levels of Nitric Oxide Completed NCT00753948 Phase 2, Phase 3 N-Nitro L-arginine-methylester (L-NAME)
14 Prevention of Low Blood Pressure in Persons With Tetraplegia Completed NCT00237770 Phase 2, Phase 3 N-Nitro L-arginine-methylester (L-NAME)
15 MEOPA to Improve Physical Therapy Results After Multilevel Surgery Completed NCT00632528 Phase 3 MEOPA;Medicinal air
16 In-home Telerehabilitation for Quadriplegic Hand Function Completed NCT00656149 Phase 2, Phase 3
17 Fenofibrate Treatment in SCI Recruiting NCT02455336 Phase 2, Phase 3 Fenofibrate
18 Restoration of Upper Limb Function in Individuals With Sub-Acute Spinal Cord Injury Active, not recruiting NCT01292811 Phase 3
19 Study of the Impact of the Use of a Corset on the Respiratory Function of Patients With Spinal Cord Injury Withdrawn NCT01569360 Phase 3
20 Cethrin in Acute Cervical Spinal Cord Injury Withdrawn NCT02053883 Phase 2, Phase 3 Cethrin (BA-210);Placebo
21 Rehabilitation of the Upper Extremity With Enhanced Proprioceptive Feedback Following Incomplete Spinal Cord Injury Unknown status NCT00833105 Phase 1, Phase 2
22 Surgical Management of Spinal Cord Injuries In Neck Unknown status NCT00475748 Phase 2
23 Safety and Efficacy of L-NAME and Midodrine to Increase MAP Completed NCT00835224 Phase 2 L-NAME;Midodrine;Placebo
24 Spinal Cord Injury Leg Rehabilitation Completed NCT01498991 Phase 1, Phase 2
25 FES Therapy:Restoring Voluntary Grasping Function in Chronic SCI Completed NCT01208688 Phase 2
26 A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries Completed NCT00500812 Phase 1, Phase 2 Cethrin
27 The Effects of Passive Gait Training in Complete Motor Spinal Cord Injury (SCI) Completed NCT01349478 Phase 1, Phase 2
28 Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury Completed NCT01484184 Phase 1, Phase 2 SPINALON (buspirone + levodopa + cardidopa)
29 Spinal Cord Neuromodulation for SCI Recruiting NCT02313194 Phase 1, Phase 2
30 24hr Effects of Tiotropium Bromide in Tetraplegia Active, not recruiting NCT02586649 Phase 2 Tiotropium Bromide;Placebo
31 Dose Escalation Study of AST-OPC1 in Spinal Cord Injury Active, not recruiting NCT02302157 Phase 1, Phase 2
32 Autologous Incubated Macrophages for Patients With Complete Spinal Cord Injuries Suspended NCT00073853 Phase 2
33 Effect of Air-stacking on Peak Cough Flow in Patients With Acute Cervical or High Thoracic Spinal Cord Injury Withdrawn NCT01046175 Phase 2
34 Effects of Anticholinergic or Long-Acting Beta 2 Agonist on FeNO and Pulmonary Function in SCI Unknown status NCT01355991 Phase 1 Tiotropium;Salmeterol
35 Improving Ambulatory Community Access After Paralysis Unknown status NCT01570816 Phase 1
36 Acute and Chronic Effects of Inhaled Steroids on Pulmonary Function in Persons With Spinal Cord Injury Unknown status NCT01353599 Phase 1 Mometasone furoate
37 The Role of Melatonin in the Regulation of Blood Coagulation Completed NCT01741389 Phase 1 Melatonin ("Circadin")
38 Evaluation of a Tongue Operated Assistive Technology for Individuals With Severe Paralysis Completed NCT01124292 Phase 1
39 Use of Interactive Gaming for Enhanced Function After Spinal Cord Injury Completed NCT01537978 Phase 1
40 The Safety of ahSC in Chronic SCI With Rehabilitation Recruiting NCT02354625 Phase 1
41 Abdominal Functional Electrical Stimulation in Tetraplegia Unknown status NCT00202631
42 Electrical Activation of The Diaphragm for Ventilatory Assist Unknown status NCT00010374
43 Abdominal Functional Electrical Stimulation Training and Its Effect on Mechanical Insufflation-Exsufflation Unknown status NCT01800409
44 Multicenter National Randomized Controlled Open Label Study Assessing Interest of Non Invasive Ventilation in out-of Hospital Setting During Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease Patients. VeNIS BPCO Unknown status NCT01626937
45 Body Composition Assessment in Spinal Cord Injury Unknown status NCT00957762
46 Early Intervention to Reduce Bone Loss After Spinal Cord Injury Unknown status NCT02334410
47 Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia Completed NCT00904436 ipratropium (Atrovent)
48 Finding the Optimal Voluntary Exercise Parameters for Those Living With Quadriplegia Completed NCT03146728
49 Abdominal Functional Electrical Stimulation (AFES) to Assist Ventilator Weaning in Tetraplegia Completed NCT02200393
50 Sleep Disordered Breathing Completed NCT01467856

Search NIH Clinical Center for Quadriplegia

Genetic Tests for Quadriplegia

Genetic tests related to Quadriplegia:

# Genetic test Affiliating Genes
1 Tetraplegia 28

Anatomical Context for Quadriplegia

MalaCards organs/tissues related to Quadriplegia:

38
Spinal Cord, Brain, Bone, Tongue, Lung, Heart, Prostate

Publications for Quadriplegia

Articles related to Quadriplegia:

(show top 50) (show all 562)
# Title Authors Year
1
Nonsurgical management of an extensive spontaneous spinal epidural hematoma causing quadriplegia and respiratory distress in a choledocholithiasis patient: A case report: Erratum. ( 29369212 )
2018
2
Disseminated coccidioidomycosis-related cervical intramedullary lesion causing quadriplegia in an immunocompetent host. ( 29237660 )
2017
3
Magnetic resonance imaging of the upper airway in patients with quadriplegia and obstructive sleep apnea. ( 29082563 )
2017
4
Active elbow flexion is possible in C4 quadriplegia using hybrid assistive limb (HALAr) technology: A case study. ( 28355990 )
2017
5
Wisdom from a Chair: Thirty Years of Quadriplegia: A Memoir by Andrew I. Batavia and Mitchell Batavia. ( 28131160 )
2017
6
Transient Hypokalemic Quadriplegia After a Lumbar Transforaminal Epidural Dexamethasone Injection: A Case Report. ( 29074369 )
2017
7
Voluntary activation of biceps-to-triceps and deltoid-to-triceps transfers in quadriplegia. ( 28253262 )
2017
8
Quadriplegia post-coronary artery bypass graft surgery: an unusual case. ( 28823182 )
2017
9
Nonsurgical management of an extensive spontaneous spinal epidural hematoma causing quadriplegia and respiratory distress in a choledocholithiasis patient: A case report. ( 29390530 )
2017
10
Correspondence: Skeletal Maturation and Mineralization of Children with Moderate to Severe Spastic Quadriplegia. ( 28571225 )
2017
11
Quadriplegia caused by an epidural abscess occurring at the same level of cervical destructive spondyloarthropathy: a case report. ( 28068970 )
2017
12
Acute quadriplegia following a minimal injury in the posterior pharyngeal wall by a fishbone. ( 28544487 )
2017
13
Fracture-dislocation at C6-C7 level with Quadriplegia after Traditional Massage in a Patient with Ankylosing Spondylitis: A Case Report. ( 29021885 )
2017
14
A severe female case of arthrogryposis multiplex congenita with brain atrophy, spastic quadriplegia and intellectual disability caused by ZC4H2 mutation. ( 29254829 )
2017
15
Midline depressed skull fracture presenting with quadriplegia: A rare phenomenon. ( 28458953 )
2017
16
WDR45B-related intellectual disability, spastic quadriplegia, epilepsy, and cerebral hypoplasia: A consistent neurodevelopmental syndrome. ( 28503735 )
2017
17
Quadriplegia Due to Injury of Corticofugal Tracts from Secondary Motor Area in a Patient With Severe Traumatic Brain Injury. ( 28301868 )
2017
18
Acute-Onset Quadriplegia With Recovery After High-Voltage Electrical Injury. ( 28953517 )
2017
19
The benefits of a comprehensive rehabilitation program in patients diagnosed with spastic quadriplegia. ( 27974931 )
2016
20
Acute Traumatic Quadriplegia in Adults: Predictors of Acute in-Hospital Mortality. ( 27651339 )
2016
21
Rapidly Progressive Quadriplegia and Encephalopathy. ( 27598246 )
2016
22
Variability Analysis on Gestures for People With Quadriplegia. ( 28113307 )
2016
23
Intraspinal hypotension syndrome presents as transient quadriplegia. ( 27766904 )
2016
24
Correlations between risk factors and functional evolution in patients with spastic quadriplegia. ( 27453749 )
2016
25
Quadriplegia Following Epileptic Seizure : Things to Keep in Mind. ( 27226869 )
2016
26
Using an Artificial Neural Bypass to Restore Cortical Control of Rhythmic Movements in a Human with Quadriplegia. ( 27658585 )
2016
27
Permanent Quadriplegia Following Replacement of Voice Prosthesis. ( 28005804 )
2016
28
Self-catheterization activity in women with quadriplegia: occupational therapy and achievement of independence. ( 27271231 )
2016
29
Orthodontic treatment and follow-up of a patient with cerebral palsy and spastic quadriplegia. ( 27692425 )
2016
30
Decrease of spasticity after hybrid assistive limb(Ar) training for a patient with C4 quadriplegia due to chronic SCI. ( 27762171 )
2016
31
Permanent Quadriplegia Following Replacement of Voice Prosthesis. ( 27617810 )
2016
32
Aspiration, quadriplegia, incontinence. ( 26607791 )
2016
33
Big data challenges in decoding cortical activity in a human with quadriplegia to inform a brain computer interface. ( 28268963 )
2016
34
Neural repair and rehabilitation: Man with quadriplegia uses brainwaves to control his forearm muscles. ( 27125635 )
2016
35
Living Brain to Hand: Bypassing Spinal Cord Quadriplegia Using a Novel Neuroprosthesis. ( 27428636 )
2016
36
Poster 472 8-Year-Old Male with Flaccid Quadriplegia After Bone Marrow Transplant: A Case Report. ( 27673216 )
2016
37
Restoring cortical control of functional movement in a human with quadriplegia. ( 27074513 )
2016
38
Skeletal Maturation and Mineralisation of Children with Moderate to Severe Spastic Quadriplegia. ( 27504366 )
2016
39
A slow progressor HIV-infected boy developing quadriplegia with evidence of Epstein-Barr virus associated smooth muscle tumour of the cervical spinal cord. ( 26123466 )
2015
40
Transient Cardiomyopathy and Quadriplegia Induced by Ephedrine Decongestant. ( 26664316 )
2015
41
Onset of reversible flaccid quadriplegia during treatment of thyrotoxic crisis. ( 25748960 )
2015
42
Acute quadriplegia caused by necrotizing myopathy in a renal transplant recipient with severe pneumonia: acute onset and complete recovery. ( 25649241 )
2015
43
Delayed transient post-traumatic quadriplegia. ( 25960840 )
2015
44
Development of stroke-induced quadriplegia after endovascular repair of blunt aortic injury pseudoaneurysm. ( 25630782 )
2015
45
Plasma Tumor Necrosis Factor-alpha (TNF-I+) Levels Correlate with Disease Severity in Spastic Diplegia, Triplegia, and Quadriplegia in Children with Cerebral Palsy. ( 26656070 )
2015
46
Post-operative quadriplegia as the initial manifestation of tumefactive multiple sclerosis. ( 26195864 )
2015
47
Paraplegia-quadriplegia Independently Increases All Percutaneous Nephrolithotomy Complications: A Comparative Study Using the Modified Clavien System. ( 25770730 )
2015
48
Management of a 3-year-old with an unstable C6-C7 diastasis without quadriplegia. ( 26077099 )
2015
49
Acute flaccid quadriplegia in rheumatoid arthritis. ( 25955377 )
2015
50
Progressive quadriplegia resulting from septic facet joint arthritis. ( 26223077 )
2015

Variations for Quadriplegia

Expression for Quadriplegia

Search GEO for disease gene expression data for Quadriplegia.

Pathways for Quadriplegia

GO Terms for Quadriplegia

Cellular components related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase complex GO:0005890 9.32 ATP1A2 ATP1A3
2 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749 9.16 SDHA SDHD
3 extracellular vesicle GO:1903561 9.13 ATP1A2 ATP1A3 SPTAN1
4 myelin sheath GO:0043209 8.92 ATP1A2 ATP1A3 PLP1 SDHA
5 membrane GO:0016020 10.03 ALDH3A2 ATP1A2 ATP1A3 ELOVL4 KANK1 PIK3C2A

Biological processes related to Quadriplegia according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 visual learning GO:0008542 9.51 ATP1A2 ATP1A3
2 cardiac muscle contraction GO:0060048 9.49 ATP1A2 ATP1A3
3 tricarboxylic acid cycle GO:0006099 9.48 SDHA SDHD
4 potassium ion import GO:0010107 9.46 ATP1A2 ATP1A3
5 cell communication by electrical coupling involved in cardiac conduction GO:0086064 9.43 ATP1A2 ATP1A3
6 cellular response to steroid hormone stimulus GO:0071383 9.4 ATP1A2 ATP1A3
7 cellular sodium ion homeostasis GO:0006883 9.37 ATP1A2 ATP1A3
8 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.32 ATP1A2 ATP1A3
9 cellular potassium ion homeostasis GO:0030007 9.26 ATP1A2 ATP1A3
10 sodium ion export across plasma membrane GO:0036376 9.16 ATP1A2 ATP1A3
11 mitochondrial electron transport, succinate to ubiquinone GO:0006121 8.96 SDHA SDHD
12 response to glycoside GO:1903416 8.62 ATP1A2 ATP1A3

Molecular functions related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chaperone binding GO:0051087 9.5 ATP1A2 ATP1A3 TBCD
2 sodium:potassium-exchanging ATPase activity GO:0005391 9.26 ATP1A2 ATP1A3
3 steroid hormone binding GO:1990239 9.16 ATP1A2 ATP1A3
4 succinate dehydrogenase (ubiquinone) activity GO:0008177 8.96 SDHA SDHD
5 succinate dehydrogenase activity GO:0000104 8.62 SDHA SDHD

Sources for Quadriplegia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....