MCID: RDL004
MIFTS: 26

Radial Neuropathy malady

Categories: Neuronal diseases

Aliases & Classifications for Radial Neuropathy

Aliases & Descriptions for Radial Neuropathy:

Name: Radial Neuropathy 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:12171
MeSH 42 D020425
SNOMED-CT 64 16644004
UMLS 69 C0748226

Summaries for Radial Neuropathy

MalaCards based summary : Radial Neuropathy is related to radial nerve lesion and neuropathy. An important gene associated with Radial Neuropathy is PC (Pyruvate Carboxylase), and among its related pathways/superpathways are Fc gamma R-mediated phagocytosis and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Pharmaceutical Solutions and 4-des-dimethylaminotetracycline have been mentioned in the context of this disorder. Related phenotype is Decreased shRNA abundance (Z-score < -2).

Wikipedia : 71 Radial neuropathy (or radial mononeuropathy) is a type of mononeuropathy which results from acute trauma... more...

Related Diseases for Radial Neuropathy

Graphical network of the top 20 diseases related to Radial Neuropathy:



Diseases related to Radial Neuropathy

Symptoms & Phenotypes for Radial Neuropathy

GenomeRNAi Phenotypes related to Radial Neuropathy according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 9.36 BRD4
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.36 PC
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.36 BRD4 PC THRB
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-171 9.36 PC
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-173 9.36 BRD4
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.36 BRD4
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.36 BRD4
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 9.36 BRD4
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-62 9.36 PC

Drugs & Therapeutics for Radial Neuropathy

Drugs for Radial Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Pharmaceutical Solutions Phase 3,Phase 2
2 4-des-dimethylaminotetracycline Phase 3
3
Heparin Approved, Investigational Phase 2 9005-49-6 772 46507594
4
Iloprost Approved, Investigational Phase 2 78919-13-8 6443959
5 calcium heparin Phase 2
6 Anesthetics Phase 2
7 Vasodilator Agents Phase 2
8 Platelet Aggregation Inhibitors Phase 2
9 Calamus Nutraceutical Phase 2
10
Epinephrine Approved, Vet_approved 51-43-4 5816
11
Lidocaine Approved, Vet_approved 137-58-6 3676
12
Benzocaine Approved 1994-09-7, 94-09-7 2337
13 tannic acid Approved, Nutraceutical
14 Mydriatics
15 Adrenergic Agents
16 Adrenergic Agonists
17 Adrenergic alpha-Agonists
18 Adrenergic beta-Agonists
19 Neurotransmitter Agents
20 Peripheral Nervous System Agents
21 Vasoconstrictor Agents
22 Epinephryl borate
23 Anti-Asthmatic Agents
24 Racepinephrine
25 Respiratory System Agents
26 Autonomic Agents
27 Bronchodilator Agents
28 Central Nervous System Depressants
29
Imidacloprid 105827-78-9 86418

Interventional clinical trials:

(show all 11)
id Name Status NCT ID Phase
1 Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A Recruiting NCT03023540 Phase 3
2 Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT) Active, not recruiting NCT02579759 Phase 3
3 The Arterial Measurement of the Blood Flow Volume After Iloprost Stimulation Recruiting NCT01774058 Phase 2
4 Delto-Tricipital Compression Syndrome: Treated With Injection of Dextrose Unknown status NCT02331069
5 Neuromuscular Ultrasound for Focal Neuropathies Completed NCT01394822
6 Effects of Light Emitting Diode Irradiation on the Conduction Parameters of the Superficial Radial Nerve Completed NCT01513148
7 Quantitation of McArdle's Sign and Evaluation of Specificity for Multiple Sclerosis Recruiting NCT03122873
8 Detection no Invasive of a Silent Myocardial Ischemia Recruiting NCT02885428
9 Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies Recruiting NCT03059420
10 Surgical Treatment of Carpal Tunnel Syndrome: Local Anesthesia With Epinephrine x Intravenous Regional Anesthesia. Not yet recruiting NCT02986347
11 Randomized Fistula Study Terminated NCT00808561

Search NIH Clinical Center for Radial Neuropathy

Genetic Tests for Radial Neuropathy

Anatomical Context for Radial Neuropathy

Publications for Radial Neuropathy

Articles related to Radial Neuropathy:

(show all 27)
id Title Authors Year
1
Poster 279 Radial Neuropathy Exacerbated by Ligamentous Laxity in Pregnancy and by Chemotherapy: A Case Report. ( 27673036 )
2016
2
Posterior interosseous neuropathy: Supinator syndrome vs fascicular radial neuropathy. ( 27683851 )
2016
3
Ultrasonographic and Surgical Findings of Acute Radial Neuropathy Following Blunt Trauma. ( 27763908 )
2016
4
Ultrasonographic and Surgical Findings of Acute Radial Neuropathy Following Blunt Trauma: A Case Report. ( 27088476 )
2016
5
The usefulness of proximal radial motor conduction in acute compressive radial neuropathy. ( 25851897 )
2015
6
Compressive radial neuropathy developed under a fibrotic band associated with rhabdomyolysis and successfully treated with surgery. ( 25024970 )
2014
7
Clinical features of wrist drop caused by compressive radial neuropathy and its anatomical considerations. ( 24851150 )
2014
8
Prognosis of acute compressive radial neuropathy. ( 22581545 )
2012
9
Diagnostic ultrasound for traumatic radial neuropathy. ( 20531154 )
2011
10
Compressive radial neuropathy induced by 'hooking' manoeuvre in a tetraplegic person. ( 20877330 )
2011
11
High-resolution 3T MR neurography of radial neuropathy. ( 21782245 )
2011
12
Superficial radial neuropathy and brachioradial motor nerve palsy associated with proximal radius osteochondroma. ( 20496292 )
2010
13
Radial neuropathy due to occupational lead exposure: Phenotypic and electrophysiological characteristics of five patients. ( 20142857 )
2009
14
Prognostic values of electrodiagnostic studies in traumatic radial neuropathy. ( 17587226 )
2007
15
Fasciitis ossificans with a radial neuropathy: a benign differential diagnosis for soft tissue sarcoma. ( 17240146 )
2007
16
Posterior antebrachial cutaneous nerve conduction study in radial neuropathy. ( 15337623 )
2004
17
A high radial neuropathy by parosteal lipoma compression. ( 12195259 )
2002
18
Superficial radial neuropathy following venepuncture. ( 11501238 )
2001
19
Maternal Bilateral Radial Neuropathy During Childbirth in Hereditary Neuropathy With a Predisposition to Pressure Palsies (HNPP). ( 19078571 )
2000
20
Superficial radial neuropathy caused by intravenous injection. ( 10427357 )
1999
21
Radial neuropathy. ( 10393751 )
1999
22
Isolated triceps weakness in exercise-induced radial neuropathy. ( 9062054 )
1996
23
Avulsion of the triceps brachii with selective radial neuropathy. ( 7761319 )
1995
24
Femoral and radial neuropathy following vascular access cannulation for hemodialysis. ( 7753288 )
1995
25
Windmill pitcher's radial neuropathy. ( 8084398 )
1994
26
Localized constrictive radial neuropathy in the absence of extrinsic compression: three cases. ( 6693752 )
1984
27
Treatment of radial neuropathy associated with fractures of the humerus. ( 7462281 )
1981

Variations for Radial Neuropathy

Expression for Radial Neuropathy

Search GEO for disease gene expression data for Radial Neuropathy.

Pathways for Radial Neuropathy

Pathways related to Radial Neuropathy according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.91 ARPC1A GSN
2 10.53 NOTCH1 THRB

GO Terms for Radial Neuropathy

Biological processes related to Radial Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 tissue regeneration GO:0042246 8.62 GSN NOTCH1

Molecular functions related to Radial Neuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chromatin DNA binding GO:0031490 8.62 NOTCH1 THRB

Sources for Radial Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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