Radiation Induced Cancer malady

Wikipedia: Up to 10% of invasive cancers are related to radiation exposure, including both ionizing radiation and...⁴⁴ more...

MalaCards: Radiation Induced Cancer, also known as radiation-induced cancer, is related to cockayne syndrome and mutagen sensitivity. An important gene associated with Radiation Induced Cancer is BRCA1 (breast cancer 1, early onset), and among its related pathways are DNA Repair Mechanisms and DNA damage Role of Brca1 and Brca2 in DNA repair. The compounds cisplatin and benzo(a)pyrene have been mentioned in the context of this disorder. Affiliated tissues include skin.

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radiation related cancer 30

Diseases related to radiation induced cancer by text searches and GeneDecks gene sharing:

(show all 17)

id	Related Disease	Score	Top Affiliating Genes
1	cockayne syndrome	28.4	XPC, BRCA1
2	mutagen sensitivity	12.4	BRCA1, XPC
3	li-fraumeni syndrome	12.4	BRCA1, XPC
4	xeroderma pigmentosum	12.4	XPC, BRCA1
5	follicular lymphoma	12.4	BRCA1, XPC
6	ataxia telangiectasia	12.4	XPC, BRCA1
7	stomach carcinoma	12.4	XPC, BRCA1
8	skin cancer	12.4	BRCA1, XPC
9	urinary bladder cancer	12.3	XPC, BRCA1
10	diffuse large b-cell lymphoma	12.3	XPC, BRCA1
11	fanconi's anemia	12.3	XPC, BRCA1
12	chronic myeloid leukemia	12.2	XPC, BRCA1
13	lung cancer susceptibility	12.2	BRCA1, XPC
14	thyroid carcinoma	12.1	XPC, BRCA1
15	b-cell lymphomas	12.1	XPC, BRCA1
16	endometrial cancer	12.0	BRCA1, XPC
17	infertility	11.8	BRCA1, XPC

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to radiation induced cancer:

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Articles related to radiation induced cancer:

id	Title	Authors	Year	Affiliating Genes
1	UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice. (12509261)	van der Horst G.T.... Friedberg E.C.	2002	XPC
2	Impact of cancer predisposition and radiosensitivity on the population risk of radiation-induced cancers. (11604087)	Sankaranarayanan K.... Chakraborty R.	2001	BRCA1
3	Cancer predisposition, radiosensitivity and the risk of radiation-induced cancers. IV. Prediction of risks in relatives of cancer-predisposed individuals. (9588361)	Chakraborty R.... Sankaranarayanan K.	1998	BRCA1

Genes related to radiation induced cancer according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	BRCA1	breast cancer 1, early onset	11.0	Publications
2	XPC	xeroderma pigmentosum, complementation group C	11.0	Publications

Pathways related to radiation induced cancer according to GeneDecks:

id	Pathway	Score	Top Affiliating Genes
1	DNA Repair Mechanisms36	9.1	BRCA1, XPC
2	DNA damage Role of Brca1 and Brca2 in DNA repair10	9.0	BRCA1, XPC
3	DNA damage_Role of Brca1 and Brca2 in DNA repair41	8.8	BRCA1, XPC

Compounds related to radiation induced cancer according to GeneDecks:

id	Compound	Score	Top Affiliating Genes
1	cisplatin32 34 9 9	12.1	BRCA1, XPC
2	benzo(a)pyrene32	8.8	BRCA1, XPC

Biological processes related to radiation induced cancer according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	DNA repair	GO:006281	9.1	BRCA1, XPC