MCID: RDT005
MIFTS: 28

Radiation Induced Cancer malady

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Radiation Induced Cancer

Aliases & Descriptions for Radiation Induced Cancer:

Name: Radiation Induced Cancer 50
Radiation-Induced Cancer 52 69
Radiation Related Cancer 50

Classifications:



Summaries for Radiation Induced Cancer

MalaCards based summary : Radiation Induced Cancer, also known as radiation-induced cancer, is related to thyroiditis and medulloblastoma. An important gene associated with Radiation Induced Cancer is BRCA1 (BRCA1, DNA Repair Associated). The drugs Dexamethasone and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and prostate.

Wikipedia : 71 Up to 10% of invasive cancers are related to radiation exposure, including both ionizing radiation and... more...

Related Diseases for Radiation Induced Cancer

Diseases related to Radiation Induced Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
id Related Disease Score Top Affiliating Genes
1 thyroiditis 9.7
2 medulloblastoma 9.5
3 cystic fibrosis 9.5
4 crohn's disease 9.5
5 lymphoma 9.5
6 sarcoma 9.5
7 prostatitis 9.5
8 squamous cell carcinoma 9.5
9 thyroid cancer 9.5
10 pigmented villonodular synovitis 9.5
11 synovitis 9.5
12 cockayne syndrome 9.5
13 testicular cancer 9.5
14 childhood medulloblastoma 9.5
15 appendicitis 9.5
16 villonodular synovitis 9.5

Graphical network of the top 20 diseases related to Radiation Induced Cancer:



Diseases related to Radiation Induced Cancer

Symptoms & Phenotypes for Radiation Induced Cancer

Drugs & Therapeutics for Radiation Induced Cancer

Drugs for Radiation Induced Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 740)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-02-2 5743
2
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23214-92-8 31703
3
Mitoxantrone Approved, Investigational Phase 4,Phase 3,Phase 2 65271-80-9 4212
4
Daunorubicin Approved Phase 4,Phase 3,Phase 2 20830-81-3 30323
5
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2068-78-2, 57-22-7 5978
6
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 33069-62-4 36314
7
Etoposide Approved Phase 4,Phase 2,Phase 3,Phase 1 33419-42-0 36462
8
Cisplatin Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 15663-27-1 84093 441203 2767
9
Idarubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 58957-92-9 42890
10
Cytarabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 147-94-4 6253
11
Teniposide Approved Phase 4 29767-20-2 34698
12
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1959-05-2, 59-05-2 126941
13
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
14
Fludarabine Approved Phase 4,Phase 3,Phase 2,Phase 1 21679-14-1, 75607-67-9 30751
15
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 174722-31-7 10201696
16
Ifosfamide Approved Phase 4,Phase 3,Phase 2,Phase 1 3778-73-2 3690
17
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
18
Dacarbazine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 4342-03-4 5351166
19
Temozolomide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 85622-93-1 5394
20
Sucralfate Approved Phase 4,Phase 3 54182-58-0
21
Amifostine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 20537-88-6 2141
22
Menthol Approved Phase 4,Phase 1,Phase 2 2216-51-5 16666
23
Cladribine Approved, Investigational Phase 4,Phase 2 4291-63-8 20279
24
Thioguanine Approved Phase 4,Phase 3,Phase 2 154-42-7 2723601
25
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
26
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
27
Vindesine Approved Phase 4,Phase 3,Phase 2 59917-39-4, 53643-48-4 40839
28
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
29
Asparaginase Approved Phase 4,Phase 3,Phase 2 9015-68-3
30
Enalapril Approved, Vet_approved Phase 4,Phase 3 75847-73-3 5362032 40466924
31
Enalaprilat Approved Phase 4,Phase 3 76420-72-9 6917719
32
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
33
Bicalutamide Approved Phase 4,Phase 3 90357-06-5 56069 2375
34
Zoledronic acid Approved Phase 4,Phase 3,Phase 2 118072-93-8 68740
35
Cevimeline Approved Phase 4 107233-08-9 83898 25137844
36
leucovorin Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 58-05-9 54575, 6560146 143
37
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 59-30-3 6037
38
Doxil Approved June 1999 Phase 4,Phase 3,Phase 2,Phase 1 31703
39 Prednisolone acetate Phase 4,Phase 3,Phase 2,Phase 1
40 Dexamethasone acetate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1177-87-3
41 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
42 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
43 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
44
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
45 Folic Acid Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
46 N-monoacetylcystine Phase 4
47 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
48 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
49 Albumin-Bound Paclitaxel Phase 4,Phase 3,Phase 2,Phase 1
50 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 1415)
id Name Status NCT ID Phase
1 ZeroTolerance Mucositis: Managing Oral and Alimentary Mucositis With High Potency Sucralfate - ProThelial Unknown status NCT02016807 Phase 4
2 THE USE OF N-ACETYLCYSTEINE ATTENUATING CISPLATIN-INDUCED TOXICITIES BY OXIDATIVE STRESS Unknown status NCT02241876 Phase 4
3 German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003) Unknown status NCT00198991 Phase 4
4 Subcutaneous Amifostine Safety Study Completed NCT00158041 Phase 4
5 Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia Completed NCT00466388 Phase 4
6 Compare the Value of Prophylactic Versus Therapeutic Breast Radiotherapy in CASODEX Completed NCT00590213 Phase 4
7 Concurrent Chemoradiotherapy (CCRT) With Paclitaxel Plus Cisplatin in LA Non-small-cell Lung Cancer (NSCLC) Completed NCT00686322 Phase 4
8 Comparison of the Ultra-low-dose Veo Algorithm With the Gold Standard Filtered Back Projection for Detecting Pulmonary Asbestos-related Conditions Completed NCT01955018 Phase 4
9 Prevention of Chemotherapy-induced Cardiotoxicity in High-risk Patients Completed NCT00292526 Phase 4
10 Taste, Smell and Chemotherapy (TASTY) Completed NCT01641172 Phase 4
11 German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99) Completed NCT00199056 Phase 4
12 German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults Completed NCT00199017 Phase 4
13 Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab Completed NCT00199004 Phase 4
14 PETHEMA LAL-RI/96: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia Completed NCT00494897 Phase 4
15 Prevention of CHOP-induced Chronic Cardiotoxicity Completed NCT00162955 Phase 4
16 German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93) Completed NCT00199069 Phase 4
17 Effectiveness of Low Energy Laser Treatment in Oral Mucositis Induced by Chemotherapy and Radiotherapy in Head and Neck Cancer Recruiting NCT01876407 Phase 4
18 Effect of Lactobacillus Brevis CD2 in Prevention of Radio-chemotherapy Induced Oral Mucositis in Head and Neck Cancer Recruiting NCT01707641 Phase 4
19 A Research About Nutrition Impact for Local Advanced Nasopharyngeal Carcinoma Patients Recruiting NCT02948699 Phase 4
20 Transarterial Radioembolization Versus Chemoembolization for the Treatment of Hepatocellular Carcinoma Recruiting NCT02729506 Phase 4
21 Effect of Cytokine-induced Killer Cells for Advanced Malignant Gliomas Not yet recruiting NCT02496988 Phase 4
22 Menthol for PDT Pain Not yet recruiting NCT02984072 Phase 4
23 A Study of Zoledronic Acid in the Prevention of Cancer Therapy-induced Bone Loss Terminated NCT00333229 Phase 4
24 Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia Unknown status NCT00081029 Phase 3
25 Intensity-Modulated Radiation Therapy in Treating Patients With Localized Prostate Cancer Unknown status NCT00392535 Phase 3
26 Induction Chemotherapy, FOLFIRINOX Followed With Concurrent Capecitabine and Radiation Therapy in Inoperable Locally Advanced Cancer of the Pancreas Unknown status NCT02311439 Phase 2, Phase 3
27 A Prospective Randomized Study Comparing the Target Volume for Limited-stage Small Cell Lung Cancer Unknown status NCT01731548 Phase 2, Phase 3
28 Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Small Cell Lung Cancer Unknown status NCT00002858 Phase 3
29 Docetaxel Based Chemotherapy Plus or Minus Induction Chemotherapy to Decrease Events in Head and Neck Cancer (DeCIDE) Unknown status NCT00117572 Phase 3
30 TPF Induction Chemotherapy for Locally Advanced and Resectable Oral Squamous Cell Carcinoma Unknown status NCT01542931 Phase 2, Phase 3
31 Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing's Sarcoma Unknown status NCT00020566 Phase 3
32 Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors Unknown status NCT00392886 Phase 3
33 COX-2 Inhibitor With Concurrent Chemoradiation in Locally Advanced Head & Neck Carcinoma Unknown status NCT00603759 Phase 3
34 Combination of Cisplatin Plus Gemcitabine Induction Chemotherapy and Intensity-modulated radiotherapyIntensity-modulated Radiotherapy With or Without Concurrent Cisplatin for NPC Unknown status NCT01854203 Phase 2, Phase 3
35 A Trial of Endostar in Combination With Chemotherapy of DF and Sequential Intensity Modulated Radiation Therapy for Patients With Advanced Nasopharyngeal Carcinoma Unknown status NCT02444949 Phase 3
36 Neoadjuvant Chemotherapy Plus/Minus Surgery in Non-Small-Cell Lung Cancer (NSCLC) Stage IIIA/N2 Unknown status NCT00273494 Phase 3
37 Combination Chemotherapy, Interleukin-2, and Peripheral Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia Unknown status NCT00004128 Phase 3
38 Recombine Endostatin With Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation in Advanced Nasopharynx Cancer Unknown status NCT01689558 Phase 2, Phase 3
39 Neoadjuvant Erbitux Based Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer Unknown status NCT01434394 Phase 2, Phase 3
40 Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors Unknown status NCT00566852 Phase 3
41 Combination Chemotherapy With or Without Filgrastim Before Surgery, High-Dose Chemotherapy, and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastoma Unknown status NCT00030719 Phase 3
42 Combination Chemotherapy With or Without Cyclophosphamide and Prednisone in Treating Older Patients With Multiple Myeloma Unknown status NCT00002653 Phase 3
43 Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Acute Myelogenous Leukemia Unknown status NCT00002549 Phase 3
44 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Promyelocytic Leukemia Unknown status NCT00002701 Phase 3
45 Observation, Combination Chemotherapy, Radiation Therapy, and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma Unknown status NCT00410631 Phase 3
46 Treatment of Acute Lymphoblastic Leukemia in Children Unknown status NCT00400946 Phase 3
47 Topical 5-ALA Photodynamic Therapy for the Treatment of Verruca Vulgaris Unknown status NCT00155584 Phase 3
48 Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL Unknown status NCT00209222 Phase 3
49 Virus Early Transcription Factor (VETF) Multicenter Phototherapy Protocol Unknown status NCT00525395 Phase 3
50 Standard Chemotherapy With or Without Nelarabine or Rituximab in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Unknown status NCT01085617 Phase 3

Search NIH Clinical Center for Radiation Induced Cancer

Genetic Tests for Radiation Induced Cancer

Anatomical Context for Radiation Induced Cancer

MalaCards organs/tissues related to Radiation Induced Cancer:

39
Skin, Thyroid, Prostate, Testes, Breast, Lung

Publications for Radiation Induced Cancer

Articles related to Radiation Induced Cancer:

(show top 50) (show all 94)
id Title Authors Year
1
Organ-specific radiation-induced cancer risk estimates due to radiotherapy for benign pigmented villonodular synovitis. ( 27499236 )
2016
2
An extra copy of p53 suppresses development of spontaneous Kras-driven but not radiation-induced cancer. ( 27453951 )
2016
3
Mass Spectrometry-Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer. ( 26880804 )
2016
4
Non-targeted effects and radiation-induced cancer. ( 27893435 )
2016
5
Epidemiological research on radiation-induced cancer in atomic bomb survivors. ( 26976124 )
2016
6
Assessment of uncertainties in radiation-induced cancer risk predictions at clinically relevant doses. ( 25563249 )
2015
7
Concerning ionizing radiation-induced cancer from internally deposited radionuclides. ( 26063349 )
2015
8
ON THE ESTIMATION OF RADIATION-INDUCED CANCER RISKS FROM VERY LOW DOSES OF RADIATION AND HOW TO COMMUNICATE THESE RISKS. ( 25802468 )
2015
9
Communicating Potential Radiation-Induced Cancer Risks From Medical Imaging Directly to Patients. ( 26295534 )
2015
10
Do we Really Need a Program to Compensate Aviation Crewmembers for Radiation-Induced Cancer? ( 25905523 )
2015
11
Radiotherapy for benign disease; assessing the risk of radiation-induced cancer following exposure to intermediate dose radiation. ( 26462717 )
2015
12
Adjustment of lifetime risks of space radiation-induced cancer by the healthy worker effect and cancer misclassification. ( 27441231 )
2015
13
Estimated risk of radiation-induced cancer from paediatric chest CT: two-year cohort study. ( 25274469 )
2014
14
Cancer risk from low dose radiation depends directly on the organ mass in a general model of radiation-induced cancer risk. ( 24562066 )
2014
15
In vivo radioadaptive response: A review of studies relevant to radiation-induced cancer risk. ( 24925363 )
2014
16
Curbing potential radiation-induced cancer risks in oncologic imaging: perspectives from the 'image gently' and 'image wisely' campaigns. ( 24855732 )
2014
17
Don't let radiation scare trump patient care: 10 ways you can harm your patients by fear of radiation-induced cancer from diagnostic imaging. ( 24764114 )
2014
18
Estimated risk of radiation-induced cancer following paediatric cranio-spinal irradiation with electron, photon and proton therapy. ( 25017376 )
2014
19
Imaging for Appendicitis: Should Radiation-induced Cancer Risks Affect Modality Selection? ( 24988435 )
2014
20
How is the risk of radiation-induced cancer influenced by background risk factors? Invited commentary on "a method for determining weights for excess relative risk and excess absolute risk when applied in the calculation of lifetime risk of cancer from radiation exposure" by Walsh and Schneider (2012). ( 23180111 )
2013
21
Patients with testicular cancer undergoing CT surveillance demonstrate a pitfall of radiation-induced cancer risk estimates: the timing paradox. ( 23249573 )
2013
22
Body CT scanning in young adults: examination indications, patient outcomes, and risk of radiation-induced cancer. ( 23386731 )
2013
23
Radiation-induced cancer: a modern view. ( 23175483 )
2012
24
Cost-effectiveness of imaging strategies to reduce radiation-induced cancer risk in Crohn's disease. ( 21928375 )
2012
25
Radiation-induced cancer cell repopulation: a possible mechanism implied by experiments using transplantable mouse-derived sarcoma cell line. ( 21206131 )
2011
26
Scientific approach to radiation-induced cancer risk. ( 22353659 )
2011
27
Latency period of radiation-induced cancer. ( 22106106 )
2011
28
Meta-analysis of non-tumour doses for radiation-induced cancer on the basis of dose-rate. ( 21250929 )
2011
29
Epidemiology of radiation-induced cancer. ( 21285730 )
2011
30
Radiation induced cancer arises from a somatic mutation. ( 21346281 )
2011
31
Neoplastic transformation in vitro: is it a valid assay or not for assessing the shape of the dose-response curve for radiation-induced cancer in vivo? ( 21595075 )
2011
32
Frequent body CT scanning of young adults: indications, outcomes, and risk for radiation-induced cancer. ( 21723488 )
2011
33
A new view of radiation-induced cancer. ( 21113062 )
2011
34
Comparison of radiation exposure and associated radiation-induced cancer risks from mammography and molecular imaging of the breast. ( 21302775 )
2010
35
Recurrent CT, cumulative radiation exposure, and associated radiation-induced cancer risks from CT of adults. ( 19332852 )
2009
36
Extrapolating radiation-induced cancer risks from low doses to very low doses. ( 19820460 )
2009
37
Mechanistic model of radiation-induced cancer after fractionated radiotherapy using the linear-quadratic formula. ( 19472619 )
2009
38
A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation. ( 19499238 )
2009
39
A new view of radiation-induced cancer: integrating short- and long-term processes. Part I: approach. ( 19536557 )
2009
40
Radiation-induced cancer after radiotherapy for non-Hodgkin's lymphoma of the head and neck: a retrospective study. ( 19591686 )
2009
41
Low-dose lung computed tomography screening before age 55: estimates of the mortality reduction required to outweigh the radiation-induced cancer risk. ( 18927099 )
2008
42
Systems biological and mechanistic modelling of radiation-induced cancer. ( 18097677 )
2008
43
Monte Carlo determination of radiation-induced cancer risks for prostate patients undergoing intensity- modulated radiation therapy. ( 18449157 )
2007
44
Radiation-induced cancer risk from annual computed tomography for patients with cystic fibrosis. ( 17717201 )
2007
45
Estimating radiation-induced cancer risks at very low doses: rationale for using a linear no-threshold approach. ( 16470411 )
2006
46
The issue of risk in complex adaptive systems: the case of low-dose radiation induced cancer. ( 16459709 )
2006
47
Understanding estimation of time and age effect-modification of radiation-induced cancer risks among atomic-bomb survivors. ( 17099404 )
2006
48
Dose-response relationship for radiation-induced cancer--decrease or plateau at high dose: in regard to Davis (Int J Radiat Oncol Biol Phys 2004;59:916). ( 15629639 )
2005
49
Does electron and proton therapy reduce the risk of radiation induced cancer after spinal irradiation for childhood medulloblastoma? A comparative treatment planning study. ( 16165914 )
2005
50
Estimation of radiation-induced cancer from three-dimensional dose distributions: Concept of organ equivalent dose. ( 15817357 )
2005

Variations for Radiation Induced Cancer

Expression for Radiation Induced Cancer

Search GEO for disease gene expression data for Radiation Induced Cancer.

Pathways for Radiation Induced Cancer

GO Terms for Radiation Induced Cancer

Sources for Radiation Induced Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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