MCID: RSM001
MIFTS: 35

Rasmussen Encephalitis malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Rasmussen Encephalitis

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Aliases & Descriptions for Rasmussen Encephalitis:

Name: Rasmussen Encephalitis 45 47
Rasmussen's Encephalitis 46
 
Rasmussen Syndrome 65
Re 45

Classifications:



External Ids:

UMLS65 C0393484

Summaries for Rasmussen Encephalitis

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NIH Rare Diseases:45 Rasmussen encephalitis is a chronic inflammatory neurological disease that usually affects only one hemisphere of the brain. it most often occurs in children under the age of 10, although adolescents and adults may also be affected. rasmussen encephalitis is characterized by frequent and severe seizures, loss of motor skills and speech, paralysis on one side of the body (hemiparesis), inflammation of the brain (encephalitis), and mental deterioration. while the cause of rasmussen encephalitis is unknown, there is evidence that in many patients it is an autoimmune disorder. immune therapy and surgery may be used for treatment. last updated: 3/22/2012

MalaCards based summary: Rasmussen Encephalitis, also known as rasmussen's encephalitis, is related to prostatitis and pancreatic cystadenocarcinoma. An important gene associated with Rasmussen Encephalitis is GRIA3 (Glutamate Ionotropic Receptor AMPA Type Subunit 3), and among its related pathways are Nicotine addiction and African trypanosomiasis. Affiliated tissues include brain, skin and b cells, and related mouse phenotypes are no phenotypic analysis and nervous system.

NINDS:46 Rasmussen?s encephalitis is a rare, chronic inflammatory neurological disease that usually affects only one hemisphere of the brain.

Related Diseases for Rasmussen Encephalitis

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Diseases in the Rasmussen Encephalitis family:

Rasmussen Subacute Encephalitis

Diseases related to Rasmussen Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 103)
idRelated DiseaseScoreTop Affiliating Genes
1prostatitis10.3
2pancreatic cystadenocarcinoma10.3CCK, SST
3biliary tract disease10.3CCK, SST
4dentin sensitivity10.3CCK, SST
5cow milk allergy10.3IFNG, IL18
6bladder lateral wall cancer10.3CCK, SST
7influenza10.3
8endotheliitis10.3
9glucose intolerance10.2CCK, SST
10female breast cancer10.2GAD1, IL18
11chronic tic disorder10.2IFNG, IL18
12metabolic acidosis10.2GZMB, IL18
13hepatoid adenocarcinoma10.2IFNG, IL18
14hypersensitivity reaction type iv disease10.1CCK, IL18, SST
15acute leukemia of ambiguous lineage10.1IFNG, IL18
16prostate cancer10.1
17leprosy10.1
18chondrosarcoma10.1
19dubin-johnson syndrome10.1
20li-fraumeni syndrome10.1
21adrenocorticotropic hormone deficiency10.1
22amelogenesis imperfecta10.1
23anencephaly10.1
24arthritis10.1
25atherosclerosis10.1
26keratopathy10.1
27leukemia10.1
28primary ciliary dyskinesia10.1
29fetal alcohol syndrome10.1
30artery disease10.1
31sleep apnea10.1
32lymphoma10.1
33stuttering10.1
34ectopic pregnancy10.1
35pleurisy10.1
36hypoparathyroidism10.1
37opioid abuse10.1
38trachoma10.1
39arteriovenous malformation10.1
40heart disease10.1
41pyelonephritis10.1
42xanthogranulomatous pyelonephritis10.1
43endocrine exophthalmos10.1
44corneal degeneration10.1
45pathological gambling10.1
46cerebral atherosclerosis10.1
47guillain-barre syndrome10.1
48conduct disorder10.1
49dementia10.1
50opisthorchiasis10.1

Graphical network of the top 20 diseases related to Rasmussen Encephalitis:



Diseases related to rasmussen encephalitis

Symptoms for Rasmussen Encephalitis

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Drugs & Therapeutics for Rasmussen Encephalitis

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Drugs for Rasmussen Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Tacrolimusapproved, investigationalPhase 2, Phase 31023104987-11-3445643, 439492, 445647
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
8-DEETHYL-8-[but-3-enyl]-ascomycin
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
FR900506
 
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
Hecoria
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus Hydrate
Tacrolimus anhydrous
Tacrolimus hydrate
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
2Immunologic FactorsPhase 2, Phase 3, Phase 118483
3Rho(D) Immune GlobulinPhase 2, Phase 3206
4Calcineurin InhibitorsPhase 2, Phase 31223
5ImmunoglobulinsPhase 2, Phase 34477
6Immunosuppressive AgentsPhase 2, Phase 310422
7AntibodiesPhase 2, Phase 34477
8Immunoglobulins, IntravenousPhase 2, Phase 3211
9
rituximabapprovedPhase 11582174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
10Antirheumatic AgentsPhase 18496

Interventional clinical trials:

idNameStatusNCT IDPhase
1Efficacy of Tacrolimus and I.V.-Immunoglobulins in Rasmussen EncephalitisActive, not recruitingNCT00545493Phase 2, Phase 3
2A Pilot Study of the Use of Rituximab in the Treatment of Chronic Focal EncephalitisCompletedNCT00259805Phase 1

Search NIH Clinical Center for Rasmussen Encephalitis

Genetic Tests for Rasmussen Encephalitis

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Anatomical Context for Rasmussen Encephalitis

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MalaCards organs/tissues related to Rasmussen Encephalitis:

33
Brain, Skin, B cells, Monocytes, Endothelial, Bone, T cells

Animal Models for Rasmussen Encephalitis or affiliated genes

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MGI Mouse Phenotypes related to Rasmussen Encephalitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.0CCK, CHRNA7, GAD1, GRIA3, IFNG, SST
2MP:00036317.3CCK, CHRNA7, GAD1, GRIA3, IFNG, IL18
3MP:00053866.9CCK, CHRNA7, GAD1, GRIA3, IFNG, IL15
4MP:00053786.7ADK, BMP6, CHRNA7, GAD1, GRIA3, IFNG

Publications for Rasmussen Encephalitis

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Articles related to Rasmussen Encephalitis:

(show top 50)    (show all 88)
idTitleAuthorsYear
1
Killer-cell immunoglobulin-like receptor and human leukocyte antigen-C genes in common variable immunodeficiency. (25860853)
2015
2
Sequential spontaneous resolution of acute syphilitic posterior placoid chorioretinitis. (25449637)
2015
3
In vivo endomicroscopy improves detection of Barrett's esophagus-related neoplasia: a multicenter international randomized controlled trial (with video). (24219822)
2014
4
Radiosensitivity in breast cancer assessed by the histone I^-H2AX and 53BP1 foci. (23617930)
2013
5
Clinical manifestations of Clostridium difficile infection in a medical center in Taiwan. (23978490)
2013
6
Subcutaneous metastasis in medulloblastoma: A case report and review of literature. (24082943)
2013
7
Therapeutic Horseback Riding Outcomes of Parent-Identified Goals for Children with Autism Spectrum Disorder: An ABA' Multiple Case Design Examining Dosing and Generalization to the Home and Community. (24091469)
2013
8
Screening for celiac disease. (24084371)
2013
9
Schistosomiasis. (22632645)
2012
10
Alternative splicing of a protein domain indispensable for function of transient receptor potential melastatin 3 (TRPM3) ion channels. (22961981)
2012
11
The role of proteinase-activated receptor-2 in idiopathic pulmonary fibrosis: is there really novel therapeutic potential here? (22336682)
2012
12
Neuromyelitis optica: circulating autoantibodies provoke astrocyte-mediated neural dysfunction. (21368284)
2011
13
Adiponectin level as a consequence of genetic variation, but not leptin level or leptin: adiponectin ratio, is a risk factor for carotid intima-media thickness. (21474811)
2011
14
Mitotic kinases regulate MT-polymerizing/MT-bundling activity of DDA3. (21473853)
2011
15
Full-thickness skin grafting with marginal deepithelialization of the defect for reconstruction of helical rim keloids. (20548227)
2010
16
Homozygosity for a rare beta 0-thalassemia mutation [frameshift codons 25/26 (+T)] causes beta-thalassemia intermedia in an Iranian family. (19205978)
2009
17
Nocardia farcinica pericarditis after kidney transplantation despite prophylaxis. (19508699)
2009
18
Portrait of PTEN: messages from mutant mice. (18201277)
2008
19
Vascular endothelial growth factor produced in nasal glands of perennial allergic rhinitis. (18702899)
2008
20
High-mobility group box 1 protein in human and murine skin: involvement in wound healing. (18239618)
2008
21
Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination. (19075292)
2008
22
High yield expression of serine/threonine protein phosphatase type 5, and a fluorescent assay suitable for use in the detection of catalytic inhibitors. (17939754)
2007
23
Initial experience with an intravenous P2Y12 platelet receptor antagonist in patients undergoing percutaneous coronary intervention: results from a 2-part, phase II, multicenter, randomized, placebo- and active-controlled trial. (16504633)
2006
24
Subendocardial and papillary muscle involvement in a patient with Churg-Strauss syndrome, detected by contrast enhanced cardiovascular magnetic resonance. (15604316)
2005
25
Downregulation of EphA7 by hypermethylation in colorectal cancer. (16007213)
2005
26
Differential recruitment of pre-mRNA splicing factors to alternatively spliced transcripts in vivo. (16231974)
2005
27
Human placenta secretes apolipoprotein B-100-containing lipoproteins. (15504742)
2004
28
A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days. (15205914)
2004
29
Hypercalcemia in patients with disseminated coccidioidomycosis. (14722391)
2004
30
ACE-inhibitors but not endothelin receptor blockers prevent podocyte loss in early diabetic nephropathy. (12802493)
2003
31
Influence of interleukin-1 gene polymorphism on periodontal regeneration in intrabony defects. (12558933)
2003
32
Tryptase precursors are preferentially and spontaneously released, whereas mature tryptase is retained by HMC-1 cells, Mono-Mac-6 cells, and human skin-derived mast cells. (12759448)
2003
33
H-Ras modulates N-methyl-D-aspartate receptor function via inhibition of Src tyrosine kinase activity. (12695509)
2003
34
trans-Complementation rescue of cyclophilin A-deficient viruses reveals that the requirement for cyclophilin A in human immunodeficiency virus type 1 replication is independent of its isomerase activity. (11836403)
2002
35
Regulation of DNA-dependent protein kinase activity by ionizing radiation-activated abl kinase is an ATM-dependent process. (10906134)
2000
36
YM905, a novel M3 antagonist, inhibits Ca2+ signaling and c-fos gene expression mediated via muscarinic receptors in human T cells. (11707312)
2000
37
Ulnar nerve lesion in the palm: report of an unusual case. (9111467)
1997
38
Extensible collagen in mussel byssus: a natural block copolymer. (9295275)
1997
39
High-dose chemotherapy with autologous peripheral blood stem cell transplantation for metastatic gastric leiomyosarcoma. (9384483)
1997
40
Acute stress disorder, subsequent posttraumatic stress disorder and depression after a series of typhoons. (9160626)
1996
41
Differential binding of HMG1, HMG2, and a single HMG box to cisplatin-damaged DNA. (8975778)
1996
42
Exercise echocardiography in combined mild mitral valve stenosis and regurgitation. (10146321)
1993
43
Expression of immunoglobulin heavy chain variable gene (VH) in B-chronic lymphocytic leukemia (B-CLL) and B-prolymphocytic leukemia (B-PLL) cell lines. "Restricted" usage of VH3 family. (1318012)
1992
44
The oxidation of ubiquinol by the isolated Rieske iron-sulfur protein in solution. (2177322)
1990
45
A double-blind cross-over study of the effect of ketotifen in urticaria pigmentosa. (6341102)
1983
46
Anterior sacral meningocele. (7281390)
1981
47
Pneumatosis cystoides intestinalis associated with progressive systemic sclerosis. (5345915)
1969
48
The ocular diagnosis of benign mucous membrane pemphigoid. (13790493)
1961
49
Congenital phimosis; the surgical repair reversed. (13658126)
1958-1959
50

Variations for Rasmussen Encephalitis

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Expression for genes affiliated with Rasmussen Encephalitis

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Search GEO for disease gene expression data for Rasmussen Encephalitis.

Pathways for genes affiliated with Rasmussen Encephalitis

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GO Terms for genes affiliated with Rasmussen Encephalitis

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Biological processes related to Rasmussen Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of tissue remodelingGO:003410510.3IL15, IL18
2positive regulation of natural killer cell proliferationGO:003281910.3IL15, IL18
3cell-cell signalingGO:00072679.4IL15, IL18, SST
4inflammatory responseGO:00069549.2BMP6, IL15, IL18
5immune responseGO:00069558.8BMP6, IFNG, IL15, IL18

Sources for Rasmussen Encephalitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet