MCID: RCT011
MIFTS: 42

Rectal Prolapse malady

Gastrointestinal diseases category

Summaries for Rectal Prolapse

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Rectal prolapse (rectal procidentia) refers to a medical condition where a section of the wall of the... more...

MalaCards: Rectal Prolapse, also known as procidentia, rectum, is related to intestinal obstruction and intussusception. An important gene associated with Rectal Prolapse is CFTR (cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)), and among its related pathways is Elastic fibre formation. The compounds trichloroacetic acid and triamcinolone acetonide have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and small intestine, and related mouse phenotypes are normal and respiratory system.

Aliases & Classifications for Rectal Prolapse

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt, 27ICD9CM, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

rectal prolapse 8 10 44 60
procidentia, rectum 8
rectal prolapse nos 8


External Ids:

Disease Ontology8 DOID:9307
MeSH34 D012005
NCIt39 C34973
ICD9CM27 569.1
ICD1025 K62.3

Related Diseases for Rectal Prolapse

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Rectal Prolapse:



Diseases related to rectal prolapse

Clinical Features for Rectal Prolapse

About this section

Drugs & Therapeutics for Rectal Prolapse

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Rectal Prolapse

Drug clinical trials:

Search ClinicalTrials for Rectal Prolapse

Search NIH Clinical Center for Rectal Prolapse

Search CenterWatch for Rectal Prolapse

Genetic Tests for Rectal Prolapse

About this section

Anatomical Context for Rectal Prolapse

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Rectal Prolapse:

32
Colon, Testes, Small intestine, Myeloid

Animal Models for Rectal Prolapse or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Rectal Prolapse:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.5CFTR, TADA3, FREM1, EFEMP2
2MP:00053888.4EFEMP2, FREM1, CFTR, ELN
3MP:00107687.2ELN, CFTR, TADA3, FREM1, EFEMP2, LSR

Publications for Rectal Prolapse

About this section
Sources:
50PubMed
See all sources

Articles related to Rectal Prolapse:

(show top 50)    (show all 504)
idTitleAuthorsYear
1
Stapled transanal longitudinal posterior proctectomy (STALPP) in total rectal prolapse: a 7-year experience. (23686679)
2013
2
Surgical correction is ineffective for improvement of dyssynergic defecation in patients with rectal prolapse. (23350052)
2013
3
Dynamic defecography in the diagnosis of paediatric rectal prolapse and related disorders. (22806602)
2012
4
Cystocele and rectal prolapse in a female dog. (23729830)
2012
5
Delorme's Procedure for Full-Thickness Rectal Prolapse; Does it Alter Anorectal Function. (24082590)
2012
6
Perineal stapled prolapse resection for complete external rectal prolapse: preliminary experience and literature review. (22441663)
2012
7
The assessment and management of rectal prolapse, rectal intussusception, rectocoele, and enterocoele in adults. (21285185)
2011
8
Controversy in the treatment of symptomatic internal rectal prolapse: suspension or resection? (21140169)
2011
9
Transanal resection of rectal lipoma mimicking rectal prolapse: description of a case and review of the literature. (22084744)
2011
10
15-Year experience in the treatment of rectal prolapse in children. (20713207)
2010
11
Rectal prolapse in children: Laparoscopic suture rectopexy is a suitable alternative. (20975780)
2010
12
Silicone elastomer sling for rectal prolapse in cats. (20676293)
2010
13
Rectal prolapse associated with extensive anorectal condyloma acuminata. (19568561)
2009
14
Abdominal posterior rectopexy with an omental pedicle for intractable rectal prolapse: a modified technique. (19554335)
2009
15
Rectal prolapse. (17021747)
2007
16
Recurrent rectal prolapse caused by colonic duplication in a dog. (17760944)
2007
17
Management of recurrent rectal prolapse: surgical approach influences outcome. (16465585)
2006
18
Laparoscopic rectovaginopexy for rectal prolapse. (17115316)
2006
19
Laparoscopic ventral recto(colpo)pexy for rectal prolapse: surgical technique and outcome for 109 patients. (17031741)
2006
20
Pelvic organ prolapse and urinary incontinence in women with surgically managed rectal prolapse: a population-based case-control study. (16273329)
2006
21
Laparoscopic rectal surgery: rectal cancer, pelvic pouch surgery, and rectal prolapse. (16905415)
2006
22
Replacement of rectal prolapse in sows. (16547186)
2006
23
Devadhar's operation for complete rectal prolapse: 25 years' experience. (15778518)
2005
24
Isolated rectal diverticulum complicating with rectal prolapse and outlet obstruction: case report. (16437704)
2005
25
Abdominal rectopexy for complete rectal prolapse: preliminary results of a new technique. (15688100)
2005
26
Rectal prolapse in autistic children. (15065049)
2004
27
Laparoscopic treatment of rectal prolapse: experience gained in a prospective multicenter study. (12172857)
2002
28
Submucosal rectal lipoma presenting as rectal prolapse. (12069471)
2002
29
Prosthetic rectopexy to the pelvic floor and sigmoidectomy for rectal prolapse. (11754852)
2001
30
Colonic motility is abnormal before surgery for rectal prolapse. (10100800)
1999
31
Successful treatment of rectal prolapse by laparoscopic suture rectopexy. (10449838)
1999
32
Anorectal function in patients with complete rectal prolapse. Differences between continent and incontinent individuals. (9866412)
1998
33
Anal continence after surgery for rectal prolapse. (9514443)
1998
34
The best operation for rectal prolapse. (9092117)
1997
35
Lymphoid hyperplasia causing recurrent rectal prolapse. (9329437)
1997
36
Management of recurrent rectal prolapse. (9221862)
1997
37
Preschool child with rectal prolapse. (9052135)
1997
38
The use of laparoscopic techniques in the surgical management of rectal prolapse. (9046193)
1996
39
Abdominal resection rectopexy versus Delorme's procedure for rectal prolapse: comparison of clinical and physiological outcomes. (8876282)
1996
40
Functional results after treatment of rectal prolapse with rectopexy and sigmoid resection. (7740801)
1995
41
Results of Delorme's procedure for rectal prolapse. (8181407)
1994
42
Prospective randomized trial of Ivalon sponge versus sutured rectopexy for full-thickness rectal prolapse. (8044618)
1994
43
Anterior resection for the treatment of rectal prolapse: a 20-year experience. (8489090)
1993
44
Clinical and functional results of abdominal rectopexy with absorbable mesh-graft for treatment of complete rectal prolapse. (8103365)
1993
45
Management of acute incarcerated rectal prolapse. Correction. (8425430)
1993
46
Abdominal rectopexy with sigmoidectomy vs. rectopexy alone for rectal prolapse: a prospective, randomized study. (1338091)
1992
47
Ruptured rectal prolapse. (2264336)
1990
48
Multiple-flap anoplasty in the treatment of rectal prolapse after pull-through operations for imperforate anus. (3819997)
1987
49
Tetrology of fallot, constipation, rectal prolapse and indentable pelvic mass. (6042805)
1967
50
Rectal prolapse in children with trichuriasis. (5980975)
1966

Genetic Variations for Rectal Prolapse

About this section

Expression for genes affiliated with Rectal Prolapse

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Rectal Prolapse

Search GEO for disease gene expression data for Rectal Prolapse.

Pathways for genes affiliated with Rectal Prolapse

About this section
Sources:
53Reactome
See all sources

Pathways related to Rectal Prolapse according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.6ELN, EFEMP2

Compounds for genes affiliated with Rectal Prolapse

About this section
Sources:
44Novoseek, 28IUPHAR, 11DrugBank
See all sources

Compounds related to Rectal Prolapse according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1trichloroacetic acid449.8ELN, CFTR
2triamcinolone acetonide44 2810.7ELN, CFTR
3formate449.6ELN, CFTR
4suramin44 28 1111.6ELN, CFTR
5dermatan sulfate449.5CFTR, ELN
6lactose44 1110.3ELN, CFTR

GO Terms for genes affiliated with Rectal Prolapse

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Rectal Prolapse according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:0056049.5FREM1, EFEMP2

Biological processes related to Rectal Prolapse according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1respiratory gaseous exchangeGO:0075859.6ELN, CFTR

Molecular functions related to Rectal Prolapse according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrix structural constituentGO:0052019.6ELN, EFEMP2

Products for genes affiliated with Rectal Prolapse

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Rectal Prolapse

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet