MCID: RCT011
MIFTS: 42

Rectal Prolapse malady

Gastrointestinal diseases category

Summaries for Rectal Prolapse

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63Wikipedia, 32MalaCards
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Wikipedia:63 Rectal prolapse (rectal procidentia) refers to a medical condition where a section of the wall of the... more...

MalaCards: Rectal Prolapse, also known as procidentia, rectum, is related to intestinal obstruction and intussusception. An important gene associated with Rectal Prolapse is CFTR (cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)), and among its related pathways is Elastic fibre formation. The compounds trichloroacetic acid and triamcinolone acetonide have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and small intestine, and related mouse phenotypes are normal and respiratory system.

Aliases & Classifications for Rectal Prolapse

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

rectal prolapse 8 10 44 60
procidentia, rectum 8
rectal prolapse nos 8


External Ids:

Disease Ontology8 DOID:9307
MeSH34 D012005
NCIt39 C34973
ICD9CM27 569.1
ICD1025 K62.3

Related Diseases for Rectal Prolapse

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Rectal Prolapse:



Diseases related to rectal prolapse

Clinical Features for Rectal Prolapse

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Drugs & Therapeutics for Rectal Prolapse

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Rectal Prolapse

Drug clinical trials:

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Search NIH Clinical Center for Rectal Prolapse

Search CenterWatch for Rectal Prolapse

Genetic Tests for Rectal Prolapse

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Anatomical Context for Rectal Prolapse

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32MalaCards
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MalaCards organs/tissues related to Rectal Prolapse:

32
Colon, Testes, Small intestine, Myeloid

Animal Models for Rectal Prolapse or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Rectal Prolapse:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.5CFTR, TADA3, FREM1, EFEMP2
2MP:00053888.4EFEMP2, FREM1, CFTR, ELN
3MP:00107687.2ELN, CFTR, TADA3, FREM1, EFEMP2, LSR

Publications for Rectal Prolapse

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50PubMed
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Articles related to Rectal Prolapse:

(show top 50)    (show all 504)
idTitleAuthorsYear
1
Evaluation and surgical treatment of rectal prolapse: an international survey. (22726304)
2013
2
Long-term outcomes of robot-assisted laparoscopic rectopexy for rectal prolapse. (23739199)
2013
3
A modified two-stage perineal rectosigmoidectomy for incarcerated rectal prolapse. (23525965)
2013
4
Total ileocolic intussusception with rectal prolapse presenting in an adult: a case report and review of the literature. (24059349)
2013
5
Precipitous intussusception with anal protrusion and complete overt rectal prolapse presenting with intestinal obstruction and an associated rectal adenoma in a young man: a case report. (24093478)
2013
6
Laparoscopic rectopexy for rectal prolapse to reduce surgical-site infections and length of stay. (23423448)
2013
7
Impact of prolapse mass on Contour Transtar technique for third-degree rectal prolapse. (23371334)
2013
8
Robot-assisted rectopexy and colpopexy for rectal prolapse. (24292077)
2013
9
Mikulicz'S procedure with levator muscle and external anal sphincter plasty in the treatment of rectal prolapse. (23399629)
2012
10
Rectal duplication cyst successfully treated by laparoscopic total mesorectal excision using the prolapsing technique. (22776303)
2011
11
Endoscopic fixation of the rectum for rectal prolapse: a feasibility and survival experimental study. (21643879)
2011
12
Complicated rectal prolapse in an infant: strangulated pararectal hernia. (21034926)
2010
13
Comparison of perineal operations with abdominal operations for full-thickness rectal prolapse. (20127331)
2010
14
Complete rectal prolapse in adults: clinical and functional results of delorme procedure combined with postanal repair. (22131652)
2010
15
Long-term outcome of Altemeier's procedure for rectal prolapse. (19404077)
2009
16
An alternative management for high-risk patients with rectal prolapse. (19055516)
2009
17
Procedure for prolapsed hemorrhoids for treatment of rectal mucosa prolapse following anorectoplasty for imperforate anus. (18481506)
2008
18
Surgery for complete rectal prolapse in adults. (18843623)
2008
19
Rectal prolapse, rectal intussusception, rectocele, solitary rectal ulcer syndrome, and enterocele. (18794001)
2008
20
Robot-assisted vs. conventional laparoscopic rectopexy for rectal prolapse: a comparative study on costs and time. (17690936)
2007
21
De novo rectal prolapse after obliterative and reconstructive vaginal surgery for urogenital prolapse. (17618769)
2007
22
Sacral nerve stimulation for fecal incontinence following surgery for rectal prolapse repair: a multicenter study. (15793647)
2005
23
Rectal prolapse: which surgical option is appropriate? (15004753)
2005
24
Perineal rectosigmoidectomy for rectal prolapse: role of levatorplasty. (15057581)
2004
25
Preserving the superior rectal artery in laparoscopic sigmoid resection for complete rectal prolapse. (15771289)
2004
26
Laparoscopic rectopexy for recurrent rectal prolapse: a safe and simple procedure without a mesh prosthesis. (12397732)
2002
27
The value of posterior levator repair in the treatment of anorectal incontinence due to rectal prolapse--a clinical and manometric study. (11382320)
2001
28
Solitary rectal ulcer syndrome presenting with rectal prolapse, severe mucorrhea and eroded polypoid hyperplasia: case report and review of the literature. (11493953)
2001
29
Surgical treatment for rectal prolapse. (11355333)
2001
30
Intussusception as a complication of rectal prolapse replacement in a ewe. (10958490)
2000
31
Sigmoid colon cancer presenting as complete rectal prolapse: report of a case. (10192740)
1999
32
Pouch perineal rectosigmoidectomy gives better functional results than conventional rectosigmoidectomy in elderly patients with rectal prolapse. (9823916)
1998
33
Comparison of polyglycolic acid and polypropylene mesh for rectopexy in the treatment of rectal prolapse. (9231856)
1997
34
Comparison of three perineal procedures for the treatment of rectal prolapse. (9305305)
1997
35
Rectal prolapse associated with bulimia nervosa: report of seven cases. (9369117)
1997
36
Sucrose as an aid to manual reduction of incarcerated rectal prolapse. (9287900)
1997
37
Defaeco-peritoneography in the diagnosis of rectal intussusception and rectal prolapse. (9240681)
1997
38
Laparoscopic-assisted abdominoperineal proctosigmoidectomy for rectal prolapse. A new technique. (9069148)
1997
39
Internal rectal intussusception seldom develops into total rectal prolapse. (9221859)
1997
40
Solitary rectal ulcer syndrome: stopping the prolapse heals the ulceration. (9241322)
1996
41
Evacuation proctography in patients with solitary rectal ulcer syndrome: anatomic abnormalities and frequency of impaired emptying and prolapse. (7998576)
1995
42
Complete rectal prolapse. (7961371)
1994
43
Abdominal rectopexy for rectal prolapse. Influence of surgical technique on functional outcome. (8055726)
1994
44
Reappraisal of Ekehorn's rectopexy in the management of rectal prolapse in children. (8301467)
1993
45
Laparoscopically assisted anterior resection for rectal prolapse. (1341537)
1992
46
Improvement of continence after abdominal rectopexy for rectal prolapse. (1588227)
1992
47
Rectal prolapse after oral cathartics. (1607611)
1992
48
Recovery of anal sphincter function following transabdominal repair of rectal prolapse: cause of improved continence? (1914749)
1991
49
Internal rectal prolapse: rubber-band ligation as treatment for a neglected disease. (2366766)
1990
50
Inflammatory cloacogenic polyp: relationship to solitary rectal ulcer syndrome/mucosal prolapse and other bowel disorders. (3500106)
1987

Genetic Variations for Rectal Prolapse

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Expression for genes affiliated with Rectal Prolapse

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Rectal Prolapse

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Pathways for genes affiliated with Rectal Prolapse

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53Reactome
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Pathways related to Rectal Prolapse according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.6ELN, EFEMP2

Compounds for genes affiliated with Rectal Prolapse

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank
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Compounds related to Rectal Prolapse according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1trichloroacetic acid449.8ELN, CFTR
2triamcinolone acetonide44 2810.7ELN, CFTR
3formate449.6ELN, CFTR
4suramin44 28 1111.6ELN, CFTR
5dermatan sulfate449.5CFTR, ELN
6lactose44 1110.3ELN, CFTR

GO Terms for genes affiliated with Rectal Prolapse

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16Gene Ontology
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Cellular components related to Rectal Prolapse according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:0056049.5FREM1, EFEMP2

Biological processes related to Rectal Prolapse according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1respiratory gaseous exchangeGO:0075859.6ELN, CFTR

Molecular functions related to Rectal Prolapse according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrix structural constituentGO:0052019.6ELN, EFEMP2

Products for genes affiliated with Rectal Prolapse

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Rectal Prolapse

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet