MCID: RCT020
MIFTS: 25

Rectum Adenocarcinoma

Categories: Cancer diseases

Aliases & Classifications for Rectum Adenocarcinoma

MalaCards integrated aliases for Rectum Adenocarcinoma:

Name: Rectum Adenocarcinoma 12 14
Adenocarcinoma of Rectum 12 69
Rectal Adenocarcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1996
NCIt 46 C9383
SNOMED-CT 64 254582000
UMLS 69 C0149978

Summaries for Rectum Adenocarcinoma

Disease Ontology : 12 A rectum cancer that derives from epithelial cells of glandular origin.

MalaCards based summary : Rectum Adenocarcinoma, also known as adenocarcinoma of rectum, is related to rectal neoplasm and rectum signet ring adenocarcinoma. An important gene associated with Rectum Adenocarcinoma is SLC14A2 (Solute Carrier Family 14 Member 2), and among its related pathways/superpathways is Cytoskeletal Signaling. Affiliated tissues include skin, lung and colon.

Related Diseases for Rectum Adenocarcinoma

Diseases related to Rectum Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 135)
# Related Disease Score Top Affiliating Genes
1 rectal neoplasm 31.0 CEACAM5 DCXR KRT20 KRT7 SLC14A2
2 rectum signet ring adenocarcinoma 11.4
3 rectum mucinous adenocarcinoma 11.0
4 anal canal adenocarcinoma 10.5 CDX2 KRT7
5 cystic basal cell carcinoma 10.5 KRT20 KRT7
6 epithelial predominant wilms' tumor 10.5 CDX2 KRT7
7 lung acinar adenocarcinoma 10.5 KRT20 KRT7
8 seminal vesicle adenocarcinoma 10.5 KRT20 KRT7
9 transverse colon cancer 10.5 KRT20 KRT7
10 ovarian large-cell neuroendocrine carcinoma 10.5 KRT20 KRT7
11 bronchiolo-alveolar adenocarcinoma 10.5 CDX2 KRT7
12 eyelid neoplasm 10.5 KRT20 KRT7
13 papillary craniopharyngioma 10.5 DNAH12 KRT7
14 malignant syringoma 10.5 KRT20 KRT7
15 krukenberg carcinoma 10.5 KRT20 KRT7
16 large intestine adenocarcinoma 10.5 KRT20 KRT7
17 linitis plastica 10.5 KRT20 KRT7
18 small cell carcinoma of the bladder 10.5 KRT20 KRT7
19 nasal cavity adenocarcinoma 10.5 CDX2 KRT7
20 adenoid squamous cell carcinoma 10.5 KRT20 KRT7
21 eccrine sweat gland neoplasm 10.5 KRT20 KRT7
22 intratubular embryonal carcinoma 10.5 KRT20 KRT7
23 bladder lymphoma 10.4 KRT20 KRT7
24 papillary serous adenocarcinoma 10.4 KRT20 KRT7
25 renal pelvis carcinoma 10.4 KRT20 KRT7
26 medulloepithelioma 10.4 KRT20 KRT7
27 glycogen-rich clear cell breast carcinoma 10.4 KRT20 KRT7
28 paget disease, extramammary 10.4 KRT20 KRT7
29 duodenum cancer 10.4 CDX2 KRT7
30 gastric tubular adenocarcinoma 10.4 CDX2 KRT7
31 mucinous cystadenocarcinoma 10.4 KRT20 KRT7
32 biliary tract neoplasm 10.4 CDX2 KRT7
33 villous adenoma 10.4 CDX2 KRT20
34 lymphoepithelioma-like carcinoma 10.4 KRT20 KRT7
35 dermoid cyst 10.4 KRT20 KRT7
36 hidradenocarcinoma 10.4 CDX2 KRT7
37 cystadenofibroma 10.4 KRT20 KRT7
38 inverted papilloma 10.4 KRT20 KRT7
39 ovarian cystic teratoma 10.4 KRT20 KRT7
40 cutaneous mucoepidermoid carcinoma 10.4 CEACAM5 KRT7
41 anal gland adenocarcinoma 10.4 CEACAM5 KRT7
42 anus adenocarcinoma 10.4 CEACAM5 KRT7
43 large cell neuroendocrine carcinoma 10.4 KRT20 KRT7
44 malignant spiradenoma 10.4 CEACAM5 KRT7
45 cutaneous adenocystic carcinoma 10.3 CEACAM5 KRT7
46 mammary paget's disease 10.3 KRT20 KRT7
47 anus cancer 10.3 CDX2 KRT7 SLC14A2
48 bile duct mucoepidermoid carcinoma 10.3 CEACAM5 KRT7
49 benign mesothelioma 10.3 KRT20 KRT7
50 prostate squamous cell carcinoma 10.3 CEACAM5 KRT7

Graphical network of the top 20 diseases related to Rectum Adenocarcinoma:



Diseases related to Rectum Adenocarcinoma

Symptoms & Phenotypes for Rectum Adenocarcinoma

Drugs & Therapeutics for Rectum Adenocarcinoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Fibroblast Before and After Neoadjuvant Chemo-radiotherapy in Patient With Locally Advanced Rectal Adenocarcinoma Recruiting NCT02849158

Search NIH Clinical Center for Rectum Adenocarcinoma

Genetic Tests for Rectum Adenocarcinoma

Anatomical Context for Rectum Adenocarcinoma

MalaCards organs/tissues related to Rectum Adenocarcinoma:

38
Skin, Lung, Colon

Publications for Rectum Adenocarcinoma

Articles related to Rectum Adenocarcinoma:

# Title Authors Year
1
A Rare Pattern of Lung Metastasis of Rectum Adenocarcinoma. ( 26784521 )
2016
2
Scrotal skin metastasis from rectum adenocarcinoma. ( 24416494 )
2013
3
Adjuvant modified FOLFOX-4 in patients with stage III rectum adenocarcinoma. ( 21790235 )
2011
4
Synchronous isolated adrenal metastasis from rectum adenocarcinoma. ( 19380305 )
2009
5
Surgical treatment of colon and rectum adenocarcinoma in elderly patients. ( 1434647 )
1992

Variations for Rectum Adenocarcinoma

Expression for Rectum Adenocarcinoma

Search GEO for disease gene expression data for Rectum Adenocarcinoma.

Pathways for Rectum Adenocarcinoma

Pathways related to Rectum Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.41 KRT20 KRT7 RAB11B RAB1A

GO Terms for Rectum Adenocarcinoma

Biological processes related to Rectum Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 melanosome transport GO:0032402 8.62 RAB11B RAB1A

Sources for Rectum Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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