MCID: RCR022
MIFTS: 46

Recurrent Acute Pancreatitis malady

Genetic diseases, Gastrointestinal diseases, Rare diseases, Endocrine diseases, Bone diseases, Immune diseases categories
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Summaries for Recurrent Acute Pancreatitis

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MalaCards based summary: Recurrent Acute Pancreatitis, also known as acute recurrent pancreatitis, is related to acute pancreatitis and pancreatitis. An important gene associated with Recurrent Acute Pancreatitis is SPINK1 (serine peptidase inhibitor, Kazal type 1). The compounds ursodeoxycholic acid and tetrodotoxin have been mentioned in the context of this disorder. Affiliated tissues include pancreas, testes and smooth muscle, and related mouse phenotypes are endocrine/exocrine gland and no phenotypic analysis.

Aliases & Classifications for Recurrent Acute Pancreatitis

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Sources:
48Orphanet, 62UMLS, 26ICD10 via Orphanet, 63UMLS via Orphanet
See all sources

Recurrent Acute Pancreatitis, Aliases & Descriptions:

Name: Recurrent Acute Pancreatitis 48
 
Acute Recurrent Pancreatitis 62


Classifications:



Characteristics (Orphanet epidemiological data):

48
recurrent acute pancreatitis:
Inheritance: Sporadic; Prevalence: 1-5/10000; Age of onset: Variable


External Ids:

ICD10 via Orphanet26 K85.0, K85.1, K85.2 K85.3, K85.8, K85.9, more
UMLS via Orphanet63 C0267937

Related Diseases for Recurrent Acute Pancreatitis

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Diseases in the Hereditary Pancreatitis family:

Acute Pancreatitis Pancreatitis
Prss1-Related Hereditary Pancreatitis Autoimmune Pancreatitis
Spink1-Related Hereditary Pancreatitis Ctrc-Related Hereditary Pancreatitis
Cftr-Related Hereditary Pancreatitis Pancreatitis, Chronic
Autoimmune Pancreatitis Type 2 Autoimmune Pancreatitis Type 1
recurrent acute pancreatitis

Diseases related to Recurrent Acute Pancreatitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 65)
idRelated DiseaseScoreTop Affiliating Genes
1acute pancreatitis31.4SPINK1, SCT, CFTR
2pancreatitis31.4SPINK1, CFTR, SCT
3cystic fibrosis30.3SPINK1, SCT, CFTR
4hereditary pancreatitis30.2CFTR, SPINK1
5pancreatic cancer30.1SCT, SPINK1
6duodenitis10.6
7hypertriglyceridemia10.4
8tropical calcific pancreatitis10.4SPINK1
9primary hyperparathyroidism10.3
10hyperparathyroidism10.3
11parkinson's disease10.3APOE
12gastric duplication cysts10.2
13acute lymphoblastic leukemia10.1
14arthritis10.1
15hepatitis10.1
16leukemia10.1
17obesity10.1
18somatostatinoma10.1
19systemic lupus erythematosus10.1
20ulcerative colitis10.1
21propionic acidemia10.1
22choledochal cyst10.1
23polycystic kidney disease10.1
24inflammatory myofibroblastic tumor10.1
25villous adenoma10.1
26cholelithiasis10.1
27sjogren's syndrome10.1
28psoriatic arthritis10.1
29wegener's granulomatosis10.1
30paraganglioma10.1
31eosinophilic gastroenteritis10.1
32intussusception10.1
33arteriovenous malformation10.1
34adenoma10.1
35cholangitis10.1
36colitis10.1
37eating disorder10.1
38gastroenteritis10.1
39giant cell tumor10.1
40kidney disease10.1
41lupus erythematosus10.1
42lymphoblastic leukemia10.1
43neuroendocrine tumor10.1
44panniculitis10.1
45peritonitis10.1
46tuberculosis10.1
47agenesis of the dorsal pancreas10.1
48annular pancreas10.1
49aneurysm10.1
50gastric outlet obstruction10.1

Graphical network of the top 20 diseases related to Recurrent Acute Pancreatitis:



Diseases related to recurrent acute pancreatitis

Symptoms for Recurrent Acute Pancreatitis

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Drugs & Therapeutics for Recurrent Acute Pancreatitis

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Drug clinical trials:

Search ClinicalTrials for Recurrent Acute Pancreatitis

Search NIH Clinical Center for Recurrent Acute Pancreatitis

Genetic Tests for Recurrent Acute Pancreatitis

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Anatomical Context for Recurrent Acute Pancreatitis

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MalaCards organs/tissues related to Recurrent Acute Pancreatitis:

32
Pancreas, Testes, Smooth muscle, Kidney, Pancreatic islet

Animal Models for Recurrent Acute Pancreatitis or affiliated genes

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MGI Mouse Phenotypes related to Recurrent Acute Pancreatitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.6APOE, CFTR, SPINK1
2MP:00030128.5SPINK1, CFTR, APOE
3MP:00053818.3APOE, CFTR, SPINK1
4MP:00053768.0APOE, SCT, CFTR, SPINK1

Publications for Recurrent Acute Pancreatitis

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Articles related to Recurrent Acute Pancreatitis:

(show top 50)    (show all 145)
idTitleAuthorsYear
1
A case of recurrent acute pancreatitis due to intra-articular corticosteroid injection. (24618449)
2014
2
Gastrointestinal: gastric outlet obstruction and air pancreatogram in the setting of recurrent acute pancreatitis. (25040618)
2014
3
Elevated Deoxycholic Acid and Idiopathic Recurrent Acute Pancreatitis: A Case Report With 48 Months of Follow-up. (24891995)
2014
4
Defining a therapeutic program for recurrent acute pancreatitis patients with unknown etiology. (24833943)
2014
5
Recurrent acute pancreatitis as a long-term complication of congenital choledochal cyst surgery. (25007026)
2014
6
PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis. (25206283)
2014
7
Recurrent acute pancreatitis in a patient with wirsungocele and neuroendocrine tumor of ampulla of Vater. (23306346)
2013
8
Roux-en-y biliary by-pass - a new approach in the treatment of hypertriglyceridemia induced recurrent acute pancreatitis. Clinical case study. (23612621)
2013
9
Gadolinium induced recurrent acute pancreatitis. (23395575)
2013
10
Recurrent acute pancreatitis and cholangitis in a patient with autosomal dominant polycystic kidney disease. (23543834)
2013
11
Recurrent acute pancreatitis: an approach to diagnosis and management. (24851521)
2013
12
Recurrent acute pancreatitis in a patient on peritoneal dialysis using 7.5% icodextrin. (22991018)
2012
13
Recurrent acute pancreatitis probably induced by rosuvastatin therapy: a case report. (22536267)
2012
14
Isoniazid-induced recurrent acute pancreatitis. (21873403)
2011
15
Recurrent acute pancreatitis caused by association of a novel mutation of the calcium-sensing receptor gene and a heterozygous mutation of the SPINK1 gene. (20335783)
2010
16
Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis. (21060690)
2010
17
SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event. (19888199)
2010
18
Recurrent acute pancreatitis caused by a gastric duplication cyst communicating with an aberrant pancreatic duct. (20647650)
2010
19
Duodenal duplication cyst communicating with the main pancreatic duct. A rare cause of recurrent acute pancreatitis. (21136003)
2010
20
A Case of Recurrent Acute Pancreatitis due to Pancreatic Arteriovenous Malformation. (20479928)
2010
21
Duodenal duplication cyst (DDC) communicating with the pancreatobiliary duct--a rare cause of recurrent acute pancreatitis in adults. (19440800)
2010
22
Recurrent acute pancreatitis secondary to a duodenal duplication cyst in an adult. A case report and literature review. (19893770)
2009
23
Cystic fibrosis transmembrane conductance regulator ion channel function testing in recurrent acute pancreatitis. (18360295)
2008
24
Cancer of the papilla causing recurrent acute pancreatitis and mimicking a pancreatic stone. (17285500)
2007
25
Recurrent acute pancreatitis in a patient with type IIb hyperlipoproteinemia: a case report and review of the literature in Korea. (16502498)
2006
26
Recurrent acute pancreatitis probably secondary to lisinopril. (17233197)
2006
27
Recurrent acute pancreatitis due to a hydatid cyst of the pancreatic head: a case report and review of the literature. (16006687)
2005
28
Hereditary pancreatitis--a rare differential diagnosis in patients with menstruation-associated recurrent acute pancreatitis: a case report. (15106365)
2004
29
Analysis of cystic fibrosis gener product (CFTR) function in patients with pancreas divisum and recurrent acute pancreatitis. (15307877)
2004
30
Recurrent acute pancreatitis after isoniazid. (15366703)
2004
31
Cystic fibrosis, pregnancy, and recurrent, acute pancreatitis. (12658041)
2003
32
Long-term results of endoscopic management of pancreas divisum with recurrent acute pancreatitis. (11868012)
2002
33
Cavernous pancreatic ductal ectasia with smooth muscle proliferation causing recurrent acute pancreatitis. (11876255)
2001
34
Aetiologies of recurrent acute pancreatitis: acute or chronic relapsing disease? (11880695)
2001
35
Recurrent Acute Pancreatitis. (11560783)
2001
36
Does recurrent acute pancreatitis lead to chronic pancreatitis? Sequential morphological and biochemical studies. (9163778)
1997
37
Recurrent panniculitis as the first clinical manifestation of recurrent acute pancreatitis secondary to cholelithiasis. (8683492)
1996
38
Prevention of recurrent acute pancreatitis in patients with severe hypertriglyceridemia: value of regular plasmapheresis. (8783340)
1996
39
Recurrent acute pancreatitis: an additional manifestation of the "wandering spleen" syndrome". (8633547)
1996
40
Recurrent acute pancreatitis as a complication of cystic fibrosis: report of one case treated surgically. (1768003)
1991
41
Recurrent acute pancreatitis--rarely idiopathic: 1989 Du Pont lecture. (2268808)
1990
42
Atypical eating disorder masquerading as recurrent acute pancreatitis: the value of multiple pancreatic serological markers. (1689331)
1990
43
Recurrent acute pancreatitis associated with pancreas divisum. (3337068)
1988
44
Pathophysiologic factors in recurrent acute pancreatitis. (3935840)
1985
45
Recurrent acute pancreatitis and intussusception complicating an intraluminal duodenal diverticulum. (6786954)
1981
46
Abscess of pancreas; a sequelae of recurrent acute pancreatitis. (13295462)
1955
47
Further clinical study of the effect of vagotomy on recurrent acute pancreatitis. (13118354)
1954
48
The surgical treatment of recurrent acute pancreatitis by endocholedochal sphincterotomy. (18901326)
1948
49
Recurrent acute pancreatitis; observations on etiology and surgical treatment. (18893291)
1948
50
Recurrent acute pancreatitis; observations on etiology and surgical treatment. (18108700)
1948

Variations for Recurrent Acute Pancreatitis

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Expression for genes affiliated with Recurrent Acute Pancreatitis

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Expression patterns in normal tissues for genes affiliated with Recurrent Acute Pancreatitis

Search GEO for disease gene expression data for Recurrent Acute Pancreatitis.

Pathways for genes affiliated with Recurrent Acute Pancreatitis

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Compounds for genes affiliated with Recurrent Acute Pancreatitis

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Compounds related to Recurrent Acute Pancreatitis according to GeneCards/GeneDecks:

(show all 42)
idCompoundScoreTop Affiliating Genes
1ursodeoxycholic acid44 24 1111.7SCT, APOE
2tetrodotoxin44 61 2811.7APOE, SCT
3thyroxine44 2410.6APOE, SCT
4guanine44 24 1111.5APOE, SCT
5formate449.5CFTR, APOE
6fluoride449.5CFTR, SPINK1
7dermatan sulfate449.5APOE, CFTR
8glibenclamide44 28 50 6112.5APOE, CFTR
9ibuprofen44 28 50 24 1113.5CFTR, APOE
10h2dids449.5SCT, CFTR
11chloroquine44 2 50 28 1113.5CFTR, APOE
12nppb28 44 6111.4SCT, CFTR
13dids44 2810.4SCT, CFTR
14suramin44 28 1111.4APOE, CFTR
15taurocholate449.4SCT, CFTR
16carbohydrates449.4CFTR, APOE
17amiloride44 28 1111.4SCT, CFTR
18bicarbonate449.4SCT, CFTR
19valine449.4CFTR, APOE
20phospholipid449.3APOE, SCT
21carbachol44 28 1111.3SCT, CFTR
22aspirin44 50 28 2412.3CFTR, APOE
23isoproterenol44 1110.3SCT, CFTR
24chloride449.2SCT, CFTR
25n acetylcysteine449.2APOE, CFTR
26epinephrine44 24 1111.1SCT, CFTR
27ascorbic acid44 2410.1CFTR, APOE
28vitamin d449.0APOE, CFTR
29trypsinogen448.9SCT, CFTR, SPINK1
30biotin44 24 1110.9CFTR, SCT, APOE
31ibmx44 61 2810.9APOE, SCT, CFTR
32indomethacin44 28 61 1111.9CFTR, SCT, APOE
33acetylcholine44 50 28 24 1112.9CFTR, SCT, APOE
34cyclosporin a44 28 6110.9APOE, SCT, CFTR
35glutamine448.9CFTR, SCT, APOE
36dopamine44 28 24 1111.9APOE, SCT, CFTR
37aspartate448.9APOE, SCT, CFTR
38testosterone44 61 24 1111.9CFTR, SCT, APOE
39glutamate448.8APOE, SCT, CFTR
40cysteine448.8CFTR, SCT, APOE
41norepinephrine44 24 1110.7SCT, CFTR
42serine448.4SPINK1, CFTR, SCT, APOE

GO Terms for genes affiliated with Recurrent Acute Pancreatitis

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Cellular components related to Recurrent Acute Pancreatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1early endosomeGO:0057698.8APOE, CFTR
2extracellular regionGO:0055768.8APOE, SCT, SPINK1

Biological processes related to Recurrent Acute Pancreatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of neuron apoptotic processGO:0435249.3APOE, SCT
2vasodilationGO:0423118.8APOE, CFTR

Products for genes affiliated with Recurrent Acute Pancreatitis

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Sources for Recurrent Acute Pancreatitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet