MCID: RCR022
MIFTS: 40

Recurrent Acute Pancreatitis malady

Genetic diseases, Gastrointestinal diseases, Rare diseases, Endocrine diseases, Skin diseases, Bone diseases, Immune diseases categories

Aliases & Classifications for Recurrent Acute Pancreatitis

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Sources:
47Orphanet, 22GTR, 60UMLS, 26ICD10 via Orphanet, 61UMLS via Orphanet
See all sources

Recurrent Acute Pancreatitis, Aliases & Descriptions:

Name: Recurrent Acute Pancreatitis 47 22
 
Acute Recurrent Pancreatitis 60


Classifications:



Characteristics (Orphanet epidemiological data):

47
recurrent acute pancreatitis:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: All ages


External Ids:

Orphanet47 64740
ICD10 via Orphanet26 K85.0, K85.1, K85.2 K85.3, K85.8, K85.9, more
UMLS via Orphanet61 C0267937

Summaries for Recurrent Acute Pancreatitis

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MalaCards based summary: Recurrent Acute Pancreatitis, also known as acute recurrent pancreatitis, is related to acute pancreatitis and pancreatitis. An important gene associated with Recurrent Acute Pancreatitis is SPINK1 (serine peptidase inhibitor, Kazal type 1). The compounds ursodeoxycholic acid and tetrodotoxin have been mentioned in the context of this disorder. Affiliated tissues include pancreas, testes and smooth muscle, and related mouse phenotypes are endocrine/exocrine gland and no phenotypic analysis.

Related Diseases for Recurrent Acute Pancreatitis

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Diseases in the Pancreatitis family:

Pancreatitis, Hereditary Acute Pancreatitis
Prss1-Related Hereditary Pancreatitis Autoimmune Pancreatitis
Spink1-Related Hereditary Pancreatitis Ctrc-Related Hereditary Pancreatitis
Cftr-Related Hereditary Pancreatitis Autoimmune Pancreatitis Type 2
Autoimmune Pancreatitis Type 1 recurrent acute pancreatitis

Diseases related to Recurrent Acute Pancreatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 64)
idRelated DiseaseScoreTop Affiliating Genes
1acute pancreatitis31.4SPINK1, SCT, CFTR
2pancreatitis31.4SPINK1, CFTR, SCT
3cystic fibrosis30.3SPINK1, SCT, CFTR
4pancreatic cancer30.1SCT, SPINK1
5duodenitis10.6
6hypertriglyceridemia10.4
7tropical calcific pancreatitis10.4SPINK1
8primary hyperparathyroidism10.3
9hyperparathyroidism10.3
10parkinson disease, late-onset10.3APOE
11adenoma10.2
12gastric duplication cysts10.2
13systemic lupus erythematosus10.1
14obesity10.1
15psoriatic arthritis10.1
16arthritis10.1
17hepatitis10.1
18leukemia10.1
19somatostatinoma10.1
20ulcerative colitis10.1
21inflammatory myofibroblastic tumor10.1
22villous adenoma10.1
23eosinophilic gastroenteritis10.1
24intussusception10.1
25choledochal cyst10.1
26polycystic kidney disease10.1
27cholelithiasis10.1
28sjogren's syndrome10.1
29arteriovenous malformation10.1
30paraganglioma10.1
31adenocarcinoma10.1
32cholangitis10.1
33colitis10.1
34eating disorder10.1
35gastroenteritis10.1
36giant cell tumor10.1
37kidney disease10.1
38lupus erythematosus10.1
39lymphoblastic leukemia10.1
40neuroendocrine tumor10.1
41panniculitis10.1
42parathyroid adenoma10.1
43peritonitis10.1
44tuberculosis10.1
45agenesis of the dorsal pancreas10.1
46annular pancreas10.1
47aneurysm10.1
48gastric outlet obstruction10.1
49hypercalcemia10.1SPINK1, SCT
50pancreatitis, hereditary10.0CFTR, SPINK1

Graphical network of the top 20 diseases related to Recurrent Acute Pancreatitis:



Diseases related to recurrent acute pancreatitis

Symptoms for Recurrent Acute Pancreatitis

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Drugs & Therapeutics for Recurrent Acute Pancreatitis

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Drug clinical trials:

Search ClinicalTrials for Recurrent Acute Pancreatitis

Search NIH Clinical Center for Recurrent Acute Pancreatitis

Genetic Tests for Recurrent Acute Pancreatitis

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Genetic tests related to Recurrent Acute Pancreatitis:

id Genetic test Affiliating Genes
1 Acute Recurrent Pancreatitis22

Anatomical Context for Recurrent Acute Pancreatitis

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MalaCards organs/tissues related to Recurrent Acute Pancreatitis:

31
Pancreas, Testes, Smooth muscle, Kidney, Pancreatic islet

Animal Models for Recurrent Acute Pancreatitis or affiliated genes

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MGI Mouse Phenotypes related to Recurrent Acute Pancreatitis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.6APOE, CFTR, SPINK1
2MP:00030128.5SPINK1, CFTR, APOE
3MP:00053818.3APOE, CFTR, SPINK1
4MP:00053768.0APOE, SCT, CFTR, SPINK1

Publications for Recurrent Acute Pancreatitis

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Articles related to Recurrent Acute Pancreatitis:

(show top 50)    (show all 149)
idTitleAuthorsYear
1
Recurrent acute pancreatitis secondary to Ascaris lumbricoides. (25851160)
2015
2
The Common Chymotrypsinogen C (CTRC) Variant G60G (C.180T) Increases Risk of Chronic Pancreatitis But Not Recurrent Acute Pancreatitis in a North American Population. (25569187)
2015
3
A case of recurrent acute pancreatitis due to intra-articular corticosteroid injection. (24618449)
2014
4
Gastrointestinal: gastric outlet obstruction and air pancreatogram in the setting of recurrent acute pancreatitis. (25040618)
2014
5
Elevated Deoxycholic Acid and Idiopathic Recurrent Acute Pancreatitis: A Case Report With 48 Months of Follow-up. (24891995)
2014
6
Defining a therapeutic program for recurrent acute pancreatitis patients with unknown etiology. (24833943)
2014
7
Recurrent acute pancreatitis as a long-term complication of congenital choledochal cyst surgery. (25007026)
2014
8
PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis. (25206283)
2014
9
Recurrent acute pancreatitis in a patient with wirsungocele and neuroendocrine tumor of ampulla of Vater. (23306346)
2013
10
Roux-en-y biliary by-pass - a new approach in the treatment of hypertriglyceridemia induced recurrent acute pancreatitis. Clinical case study. (23612621)
2013
11
Gadolinium induced recurrent acute pancreatitis. (23395575)
2013
12
Recurrent acute pancreatitis and cholangitis in a patient with autosomal dominant polycystic kidney disease. (23543834)
2013
13
Recurrent acute pancreatitis: an approach to diagnosis and management. (24851521)
2013
14
Recurrent acute pancreatitis in a patient on peritoneal dialysis using 7.5% icodextrin. (22991018)
2012
15
Recurrent acute pancreatitis probably induced by rosuvastatin therapy: a case report. (22536267)
2012
16
Isoniazid-induced recurrent acute pancreatitis. (21873403)
2011
17
Recurrent acute pancreatitis caused by association of a novel mutation of the calcium-sensing receptor gene and a heterozygous mutation of the SPINK1 gene. (20335783)
2010
18
Recurrent Acute Pancreatitis and Therapy for Ulcerative Colitis. (21060690)
2010
19
SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event. (19888199)
2010
20
Recurrent acute pancreatitis caused by a gastric duplication cyst communicating with an aberrant pancreatic duct. (20647650)
2010
21
Duodenal duplication cyst communicating with the main pancreatic duct. A rare cause of recurrent acute pancreatitis. (21136003)
2010
22
A Case of Recurrent Acute Pancreatitis due to Pancreatic Arteriovenous Malformation. (20479928)
2010
23
Recurrent acute pancreatitis secondary to a duodenal duplication cyst in an adult. A case report and literature review. (19893770)
2009
24
Cystic fibrosis transmembrane conductance regulator ion channel function testing in recurrent acute pancreatitis. (18360295)
2008
25
Cancer of the papilla causing recurrent acute pancreatitis and mimicking a pancreatic stone. (17285500)
2007
26
Recurrent acute pancreatitis in a patient with type IIb hyperlipoproteinemia: a case report and review of the literature in Korea. (16502498)
2006
27
Recurrent acute pancreatitis probably secondary to lisinopril. (17233197)
2006
28
Recurrent acute pancreatitis due to a hydatid cyst of the pancreatic head: a case report and review of the literature. (16006687)
2005
29
Hereditary pancreatitis--a rare differential diagnosis in patients with menstruation-associated recurrent acute pancreatitis: a case report. (15106365)
2004
30
Analysis of cystic fibrosis gener product (CFTR) function in patients with pancreas divisum and recurrent acute pancreatitis. (15307877)
2004
31
Recurrent acute pancreatitis after isoniazid. (15366703)
2004
32
Cystic fibrosis, pregnancy, and recurrent, acute pancreatitis. (12658041)
2003
33
Long-term results of endoscopic management of pancreas divisum with recurrent acute pancreatitis. (11868012)
2002
34
Cavernous pancreatic ductal ectasia with smooth muscle proliferation causing recurrent acute pancreatitis. (11876255)
2001
35
Aetiologies of recurrent acute pancreatitis: acute or chronic relapsing disease? (11880695)
2001
36
Does recurrent acute pancreatitis lead to chronic pancreatitis? Sequential morphological and biochemical studies. (9163778)
1997
37
Recurrent panniculitis as the first clinical manifestation of recurrent acute pancreatitis secondary to cholelithiasis. (8683492)
1996
38
Prevention of recurrent acute pancreatitis in patients with severe hypertriglyceridemia: value of regular plasmapheresis. (8783340)
1996
39
Recurrent acute pancreatitis: an additional manifestation of the "wandering spleen" syndrome". (8633547)
1996
40
Recurrent acute pancreatitis as a complication of cystic fibrosis: report of one case treated surgically. (1768003)
1991
41
Recurrent acute pancreatitis--rarely idiopathic: 1989 Du Pont lecture. (2268808)
1990
42
Atypical eating disorder masquerading as recurrent acute pancreatitis: the value of multiple pancreatic serological markers. (1689331)
1990
43
Recurrent acute pancreatitis associated with pancreas divisum. (3337068)
1988
44
Pathophysiologic factors in recurrent acute pancreatitis. (3935840)
1985
45
Recurrent acute pancreatitis and intussusception complicating an intraluminal duodenal diverticulum. (6786954)
1981
46
Abscess of pancreas; a sequelae of recurrent acute pancreatitis. (13295462)
1955
47
Further clinical study of the effect of vagotomy on recurrent acute pancreatitis. (13118354)
1954
48
The surgical treatment of recurrent acute pancreatitis by endocholedochal sphincterotomy. (18901326)
1948
49
Recurrent acute pancreatitis; observations on etiology and surgical treatment. (18893291)
1948
50
Recurrent acute pancreatitis; observations on etiology and surgical treatment. (18108700)
1948

Variations for Recurrent Acute Pancreatitis

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Expression for genes affiliated with Recurrent Acute Pancreatitis

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Search GEO for disease gene expression data for Recurrent Acute Pancreatitis.

Pathways for genes affiliated with Recurrent Acute Pancreatitis

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Compounds for genes affiliated with Recurrent Acute Pancreatitis

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Compounds related to Recurrent Acute Pancreatitis according to GeneCards Suite gene sharing:

(show all 42)
idCompoundScoreTop Affiliating Genes
1ursodeoxycholic acid43 24 1211.7SCT, APOE
2tetrodotoxin43 59 2811.7APOE, SCT
3thyroxine43 2410.6APOE, SCT
4guanine43 24 1211.5APOE, SCT
5formate439.5CFTR, APOE
6fluoride439.5CFTR, SPINK1
7dermatan sulfate439.5APOE, CFTR
8glibenclamide43 28 49 5912.5APOE, CFTR
9ibuprofen43 28 49 24 1213.5CFTR, APOE
10h2dids439.5SCT, CFTR
11chloroquine43 2 49 28 1213.5CFTR, APOE
12nppb28 43 5911.4SCT, CFTR
13dids43 2810.4SCT, CFTR
14suramin43 28 1211.4APOE, CFTR
15taurocholate439.4SCT, CFTR
16carbohydrates439.4CFTR, APOE
17amiloride43 28 1211.4SCT, CFTR
18bicarbonate439.4SCT, CFTR
19valine439.4CFTR, APOE
20phospholipid439.3APOE, SCT
21carbachol43 28 1211.3SCT, CFTR
22aspirin43 49 28 2412.3CFTR, APOE
23isoproterenol43 1210.3SCT, CFTR
24chloride439.2SCT, CFTR
25n acetylcysteine439.2APOE, CFTR
26epinephrine43 24 1211.1SCT, CFTR
27ascorbic acid43 2410.1CFTR, APOE
28vitamin d439.0APOE, CFTR
29trypsinogen438.9SCT, CFTR, SPINK1
30biotin43 24 1210.9CFTR, SCT, APOE
31ibmx43 59 2810.9APOE, SCT, CFTR
32indomethacin43 28 59 1211.9CFTR, SCT, APOE
33acetylcholine43 49 28 24 1212.9CFTR, SCT, APOE
34cyclosporin a43 28 5910.9APOE, SCT, CFTR
35glutamine438.9CFTR, SCT, APOE
36dopamine43 28 24 1211.9APOE, SCT, CFTR
37aspartate438.9APOE, SCT, CFTR
38testosterone43 59 24 1211.9CFTR, SCT, APOE
39glutamate438.8APOE, SCT, CFTR
40cysteine438.8CFTR, SCT, APOE
41norepinephrine43 24 1210.7SCT, CFTR
42serine438.4SPINK1, CFTR, SCT, APOE

GO Terms for genes affiliated with Recurrent Acute Pancreatitis

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Cellular components related to Recurrent Acute Pancreatitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1early endosomeGO:00057698.8APOE, CFTR
2extracellular regionGO:00055768.8APOE, SCT, SPINK1

Biological processes related to Recurrent Acute Pancreatitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of neuron apoptotic processGO:00435249.3APOE, SCT
2vasodilationGO:00423118.8APOE, CFTR

Products for genes affiliated with Recurrent Acute Pancreatitis

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Sources for Recurrent Acute Pancreatitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet