MCID: RCR001
MIFTS: 34

Recurrent Corneal Erosion malady

Category: Eye diseases

Aliases & Classifications for Recurrent Corneal Erosion

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Aliases & Descriptions for Recurrent Corneal Erosion:

Name: Recurrent Corneal Erosion 11 13
Recurrent Erosion of Cornea 11 66
 
Recurrent Erosion Syndrome 11

Classifications:



External Ids:

Disease Ontology11 DOID:11541
ICD1028 H18.83
ICD9CM30 371.42

Summaries for Recurrent Corneal Erosion

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Wikipedia:69 Recurrent corneal erosion is a disorder of the eyes characterized by the failure of the cornea\'s... more...

MalaCards based summary: Recurrent Corneal Erosion, also known as recurrent erosion of cornea, is related to corneal deposit and epithelial recurrent erosion dystrophy. An important gene associated with Recurrent Corneal Erosion is IL1B (Interleukin 1 Beta), and among its related pathways are Transcription_Role of VDR in regulation of genes involved in osteoporosis and African trypanosomiasis. Affiliated tissues include eye.

Related Diseases for Recurrent Corneal Erosion

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Diseases related to Recurrent Corneal Erosion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 191)
idRelated DiseaseScoreTop Affiliating Genes
1corneal deposit27.5CXCL8, DNAJC9, IL1B, IL6, TGFBI
2epithelial recurrent erosion dystrophy11.4
3scrotum paget's disease10.4IL1B, IL6
4midline interhemispheric variant of holoprosencephaly10.4IL1B, IL6
5hemoglobinopathy10.4IL1B, IL6
6melorheostosis10.4IL1B, IL6
7hypothyroidism10.4IL1B, IL6
8autoimmune polyendocrine syndrome10.4IL1B, IL6
9conventional leiomyosarcoma10.4IL1B, IL6
10scarlet fever10.4IL1B, IL6
11lung occult adenocarcinoma10.4IL1B, IL6
12non-secretory myeloma10.4IL1B, IL6
13sterility due to immotile flagella10.4IL1B, IL6
14syphilitic encephalitis10.4IL1B, IL6
15periodic paralyses10.4IL1B, IL6
16scn8a encephalopathy10.4IL1B, IL6
17human monocytic ehrlichiosis10.4IL1B, IL6
18philophthalmiasis10.4IL1B, IL6
19thoracic aortic aneurysm10.4IL1B, IL6
20ulcerative colitis10.4IL1B, IL6
21ampulla of vater neoplasm10.4IL1B, IL6
22renal artery disease10.4IL1B, IL6
23foodborne botulism10.4IL1B, IL6
24echinococcosis10.4IL1B, IL6
25keloids10.3IL1B, IL6
26senile cataract10.3IL1B, IL6
27osmotic diarrhea10.3IL1B, IL6
28oesophagostomiasis10.3IL1B, IL6
29gastric dilatation10.3IL1B, IL6
30ehlers-danlos syndrome, musculocontractural type10.3IL1B, IL6
31benign lymphoepithelial lesion of salivary gland10.3IL1B, IL6
32isolated congenital auditory ossicle malformation10.3IL1B, IL6
33brain meningioma10.3IL1B, IL6
34corneal intraepithelial neoplasm10.3IL1B, IL6
35retroperitoneal fibrosis10.3IL1B, IL6
36benign peritoneal mesothelioma10.3IL1B, IL6
37cutaneous porphyria10.3IL1B, IL6
38contact blepharoconjunctivitis10.3CXCL8, IL1B
39parametrium malignant neoplasm10.3IL1B, IL6
40plantar wart10.3CXCL8, IL1B
41amyotrophic lateral sclerosis type 410.3CXCL8, IL1B
42paraphimosis10.3CXCL8, IL1B
43intervertebral disc disease10.3IL1B, IL6
44burns10.3CXCL8, IL1B
45atrophic rhinitis10.3IL1B, IL6
46pseudoretinitis pigmentosa10.3CXCL8, IL1B
47opportunistic bacterial infectious disease10.3IL1B, IL6
48hidradenitis suppurativa10.3CXCL8, IL1B
49inner ear cancer10.3CXCL8, IL1B
50herpes zoster10.3IL1B, IL6

Graphical network of the top 20 diseases related to Recurrent Corneal Erosion:



Diseases related to recurrent corneal erosion

Symptoms for Recurrent Corneal Erosion

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Drugs & Therapeutics for Recurrent Corneal Erosion

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Drugs for Recurrent Corneal Erosion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Pseudoephedrine56990-82-47028
Synonyms:
( )-Pseudoephedrine
(+)-(1S,2S)-Pseudoephedrine
(+)-Pseudoephedrine
(+)-Psi-ephedrine
(+)-psi-Ephedrine
(+)-threo-Ephedrine
(1S,2S)-(+)-Pseudoephedrine
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol
(1S,2S)-2-Methylamino-1-phenyl-1-propanol
(1S,2S)-Pseudoephedrine
(1S,2S)-Pseudoephedrine, polymer-bound
1-Ephedrine
2-(Methylamino)-1-phenyl-1-propanol
287636_ALDRICH
304-87-0
30987-59-8
37577-31-4
649031_ALDRICH
90-82-4
AC-20292
AC1L1NUA
Acunaso
Acunaso (TN)
Afrinol
BIDD:GT0817
BRD-K84175871-003-02-2
BSPBio_003261
Balminil Decongestant Syrup
Benylin Decongestant
Benzenemethanol, alpha-((1S)-1-(methylamino)ethyl)-, (alpha-S)- (9CI)
Besan
C02765
C10H15NO
CHEBI:51209
CHEMBL1590
CID7028
CPD-9954
Cenafed
D-Isoephedrine
D-Pseudoephedrine
D-Pseudoephedrine base
D-Psi-2-Methylamino-1-phenyl-1-propanol
D-Psi-2-methylamino-1-phenyl-1-propanol
D-Psi-Ephedrine
D-Psi-ephedrine
D08449
DB00852
Decofed
Dimetapp Decongestant
Dimetapp Decongestant Pediatric Drops
DivK1c_000451
Drixoral N.D.
Drixoral Nasal Decongestant
EINECS 202-018-6
Efidac 24 Pseudoephedrine Hcl
Efidac/24
Eltor 120
Ephedrine
Genaphed
HSDB 3177
I01-8928
IDI1_000451
 
Isoephedrine
KBio1_000451
KBio2_001358
KBio2_003926
KBio2_006494
KBio3_002762
KBioGR_001763
KBioSS_001358
L(+)-Psi-Ephedrine
L(+)-Psi-ephedrine
L(+)-psi-Ephedrine
L-(+)-Pseudoephedrine
LS-125922
Lopac-E-3250
Maxenal
MolPort-001-684-474
Myfedrine
NCGC00015408-01
NCGC00178180-01
NCI60_002955
NINDS_000451
Neodurasina
Neodurasina (TN)
Novafed
PDSP1_001347
PSEUDOEPHEDRINE
Pedia Care
Pseudo
Pseudo 60's
Pseudo-12
Pseudoefedrina
Pseudoefedrina [INN-Spanish]
Pseudoephedrine
Pseudoephedrine (D)
Pseudoephedrine (INN)
Pseudoephedrine D-form
Pseudoephedrine Ephedrine
Pseudoephedrine [INN:BAN]
Pseudoephedrine d-form
Pseudoephedrinum
Pseudoephedrinum [INN-Latin]
Psi-ephedrin
Psi-ephedrine
Robidrine
SPBio_001365
STOCK1N-42675
Spectrum2_001303
Spectrum3_001771
Spectrum4_001162
Spectrum5_000650
Spectrum_000878
Sudafed
Sudafed Decongestant
Sudafed Decongestant 12 Hour
Sudafed Decongestant Extra Strength
Triaminic AM Decongestant Formula
Triaminic Infant Oral Decongestant Drops
UNII-7CUC9DDI9F
alpha-(1-(Methylamino)ethyl)benzyl alcohol
d-Isoephedrine
d-Pseudoephedrine
d-psi-2-Methylamino-1-phenyl-1-propanol
d-psi-Ephedrine
trans-Ephedrine
2
Ephedrine569299-42-39294
Synonyms:
( )-Pseudoephedrine
(+)-Ephedrin
(+)-Ephedrine
(+)-Pseudoephedrine
(+)-psi-Ephedrine
(+)-threo-Ephedrine
(+-)-Ephedrine
(-)-Ephedrine
(-)-Pseudoephedrine
(-)-psi-Ephedrine
(-)-threo-Ephedrine
(1R,2R)-Ephedrine
(1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane
(1S,2R)-Ephedrine
(L)-EPHEDRINE
--EPHEDRINE
1-EPHEDRINE
1-Sedrin
134910_ALDRICH
287636_ALDRICH
287644_ALDRICH
299-42-3
304-87-0
30987-59-8
321-96-0
321-97-1
321-98-2
37577-31-4
38732-95-5
45261_FLUKA
4607-45-8
50-98-6
50906-05-3
53214-57-6
649031_ALDRICH
6912-63-6
7009-81-6
90-82-4
968-63-8
AC-20231
AC-20292
AC1L1JGK
AC1L1NUA
AC1L1RFA
AC1L1SR1
AC1L1T31
AC1L1Y3M
AC1O8JUO
AC1Q3XJE
AC1Q3XJM
AC1Q3XJN
AC1Q59F5
AC1Q7701
AI3-02761
AKOS000268842
AR-1A0126
AR-1I7143
Acunaso
Acunaso (TN)
Afrinol
Ambap299-42-3
BIDD:GT0817
BRN 3197916
BRN 4231286
BSPBio_001946
BSPBio_001968
BSPBio_003261
Benylin Decongestant
Besan
Biophedrin
C01575
C02765
C10H15NO
CHEBI:15407
CHEBI:51209
CHEMBL1590
CHEMBL211456
CHEMBL357080
CID11972440
CID5032
CID62946
CID6710657
CID7028
CID8650
CID9294
CID9457
CPD-9954
CPDD 0049
Cenafed
D00124
D08449
DB00852
DB01364
Decofed
DivK1c_000181
DivK1c_000451
DivK1c_000461
Drixoral N.D.
EINECS 202-017-0
EINECS 202-018-6
EINECS 206-080-5
EINECS 206-292-8
EINECS 206-293-3
Eciphin
Efedrin
Efidac/24
Eltor 120
Ephedral
Ephedremal
Ephedrin
Ephedrine
Ephedrine (TN)
Ephedrine (USP)
Ephedrine [USAN:BAN]
Ephedrine l-form
Ephedrital
Ephedrol
Ephedrosan
Ephedrotal
Ephedsol
Ephendronal
Ephoxamin
Fedrin
Genaphed
HSDB 3072
HSDB 3177
I-Sedrin
I01-3584
I01-8925
I01-8928
 
IDI1_000181
IDI1_000451
IDI1_000461
Isoephedrine
Jsp005664
KBio1_000181
KBio1_000451
KBio1_000461
KBio2_001358
KBio2_001500
KBio2_003926
KBio2_004068
KBio2_006494
KBio2_006636
KBio3_001188
KBio3_001446
KBio3_002762
KBioGR_001013
KBioGR_001763
KBioSS_001358
KBioSS_001500
KST-1A9168
Kratedyn
L(+)-psi-Ephedrine
L(-)-Ephedrine
L-(+)-Ephedrine
L-(-)-Ephedrine
L-Ephedrine
L-erythro-2-(Methylamino)-1-phenylpropan-1-ol
L000968
LS-125921
LS-125922
LS-43083
LS-63961
LS-63962
LS-63963
LS-63964
Lexofedrin
Lopac-E-3250
Lopac0_000501
MLS000069657
Manadrin
Mandrin
Maxenal
MolPort-001-684-474
MolPort-001-684-477
MolPort-001-684-478
MolPort-001-684-479
MolPort-001-769-085
Myfedrine
NCGC00015408-01
NCGC00015408-02
NCGC00162174-01
NCGC00178180-01
NCGC00178889-01
NCI-C55652
NCI60_002955
NINDS_000181
NINDS_000451
NINDS_000461
NSC 165609
NSC 170951
NSC 8971
NSC165609
NSC170951
NSC8971
Nasol
Neodurasina
Neodurasina (TN)
Oprea1_287330
PDSP1_000168
PDSP1_001106
PDSP1_001343
PDSP1_001345
PDSP1_001346
PDSP1_001347
PDSP2_000167
PDSP2_001090
PDSP2_001327
PDSP2_001329
PDSP2_001330
PDSP2_001331
PSEUDOEPHEDRINE
Pedia Care
Pseudo
Pseudo 60's
Pseudo-12
Pseudoefedrina
Pseudoephedrine (D)
Pseudoephedrinum
Psi-ephedrin
Psi-ephedrine
Robidrine
SMR000059174
SPBio_000214
SPBio_001365
SPBio_001377
ST023802
STK367993
STOCK1N-42675
Sanedrine
Spectrum2_000137
Spectrum2_001303
Spectrum2_001309
Spectrum3_000414
Spectrum3_000563
Spectrum3_001771
Spectrum4_000497
Spectrum4_001162
Spectrum5_000650
Spectrum5_000879
Spectrum5_001106
Spectrum_000878
Spectrum_001020
Sudafed
Sudafed Decongestant
UNII-03VRY66076
UNII-7CUC9DDI9F
UNII-GN83C131XS
Vencipon
WLN: QYR & Y1 & M1
WLN: QYR&Y1&M1
Zephrol
d-Ephedrine
d-Isoephedrine
d-Pseudoephedrine
d-psi-Ephedrine
l-Ephedrine
l-Pseudoephedrine
racephedrine
trans-Ephedrine

Interventional clinical trials:

idNameStatusNCT IDPhase
1Phototherapeutic Keratectomy (PTK) on Recurrent Corneal ErosionsCompletedNCT01251692Phase 4
2Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic KeratectomyRecruitingNCT02373397Phase 4
3Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG LaserCompletedNCT00816738
4Umbilical Cord Serum Eye DropsCompletedNCT01016158
5Study of Dehydrex in Patients With Corneal ErosionCompletedNCT00029185
6Metalloproteinases and Recurrent Corneal Erosion SyndromeNot yet recruitingNCT02891694

Search NIH Clinical Center for Recurrent Corneal Erosion

Genetic Tests for Recurrent Corneal Erosion

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Anatomical Context for Recurrent Corneal Erosion

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MalaCards organs/tissues related to Recurrent Corneal Erosion:

34
Eye

Animal Models for Recurrent Corneal Erosion or affiliated genes

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Publications for Recurrent Corneal Erosion

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Articles related to Recurrent Corneal Erosion:

(show top 50)    (show all 79)
idTitleAuthorsYear
1
A COL17A1 Splice-Altering Mutation Is Prevalent in Inherited Recurrent Corneal Erosions. (26786512)
2016
2
Recurrent corneal erosion syndrome associated with oral isotretinoin: a cautionary tale. (26932827)
2016
3
Long-Term Outcomes of Epithelial Debridement and Diamond Burr Polishing for Corneal Epithelial Irregularity and Recurrent Corneal Erosion. (26203746)
2015
4
Phototherapeutic keratectomy (PTK) for treatment of recurrent corneal erosion: Correlation between etiology and prognosis - prospective longitudinal study. (25900814)
2015
5
Optical coherence tomography findings in recurrent corneal erosion syndrome. (25532997)
2015
6
Superior Perilimbal Epitheliopathy in Recurrent Corneal Erosion Syndrome. (26203756)
2015
7
Authors' response: A randomised controlled trial of alcohol delamination and phototherapeutic keratectomy for the treatment of recurrent corneal erosion syndrome. (24352600)
2014
8
Anterior stromal puncture for the treatment of recurrent corneal erosion syndrome: patient clinical features and outcomes. (24439438)
2014
9
Changes of clinical manifestation of granular corneal deposits because of recurrent corneal erosion in granular corneal dystrophy types 1 and 2. (23132456)
2013
10
Randomized Controlled Study of Ocular Lubrication Versus Bandage Contact Lens in the Primary Treatment of Recurrent Corneal Erosion Syndrome. (23974885)
2013
11
Interventions for recurrent corneal erosion: a Cochrane Systematic review. (23989116)
2013
12
Epithelial debridement with diamond burr superficial keratectomy for the treatment of recurrent corneal erosion. (23230823)
2013
13
Recurrent Corneal Erosion Syndrome. (26107728)
2012
14
Recurrent corneal erosion following uneventful IntraLASIK treated by phototherapeutic keratectomy. (22180150)
2012
15
Franceschetti hereditary recurrent corneal erosion. (22402249)
2012
16
Treatment of recurrent corneal erosion by extended-wear bandage contact lens. (20847650)
2011
17
Alcohol delamination in the treatment of recurrent corneal erosion: an electron microscopic study. (20606026)
2010
18
Recurrent corneal erosions and epithelial basement membrane dystrophy. (20724847)
2010
19
Recurrent Corneal Erosion Syndrome: A Study of 364 Episodes. (20337327)
2010
20
Treatment of recurrent corneal erosion syndrome using the combination of oral doxycycline and topical corticosteroid. (18290949)
2008
21
In vivo biopsy by laser confocal microscopy for evaluation of traumatic recurrent corneal erosion. (19093010)
2008
22
Recurrent corneal erosion syndrome. (19026329)
2008
23
Recurrent corneal erosion syndrome. (18191654)
2008
24
Alcohol delamination of the corneal epithelium for recalcitrant recurrent corneal erosion syndrome: a prospective study of efficacy and safety. (17301117)
2007
25
Upregulation of matrix metalloproteinase in tear fluid of patients with recurrent corneal erosion. (17926110)
2007
26
Recurrent corneal erosion. (17908600)
2007
27
Small spot phototherapeutic keratectomy for recurrent corneal erosion. (17912944)
2007
28
Long-term efficacy of phototherapeutic keratectomy on recurrent corneal erosion syndrome. (17172888)
2006
29
The cleavage plane of corneal epithelial adhesion complex in traumatic recurrent corneal erosion. (16604052)
2006
30
Treatment of recurrent corneal erosion with substance P-derived peptide and insulin-like growth factor I. (16219742)
2005
31
Successful management of three consecutive cases of recurrent corneal erosion with botulinum toxin injections. (14765101)
2004
32
Anterior basement membrane corneal dystrophy and pseudo-unilateral lattice corneal dystrophy in a patient with recurrent corneal erosions. (15183802)
2004
33
Anterior stromal puncture for recurrent corneal erosion after laser in situ keratomileusis. (15030848)
2004
34
Observation of tear film in recurrent corneal erosion and epithelial basement membrane dystrophy. (12613981)
2002
35
Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. (11438047)
2001
36
Excimer laser phototherapeutic keratectomy for recurrent corneal erosion. (9584237)
1998
37
Recurrent corneal erosion associated with Alport's syndrome. Rapid communication. (9211364)
1997
38
Combined PRK and PTK in myopic patients with recurrent corneal erosion. (9290367)
1997
39
The natural history and management of recurrent corneal erosion: a prospective randomised trial. (8013716)
1994
40
Excimer laser phototherapeutic keratectomy for treatment of recurrent corneal erosion. (8201570)
1994
41
Successful treatment of recurrent corneal erosion with Nd:YAG anterior stromal puncture. (1992755)
1991
42
Successful treatment of recurrent corneal erosion with Nd:YAG anterior stromal puncture. (2220975)
1990
43
Recurrent corneal erosion. (2803088)
1989
44
Recurrent corneal erosion, microcystic epithelial dystrophy, map configurations and fingerprint lines in the cornea. (3490898)
1986
45
Posttraumatic recurrent corneal erosion. 1. Clinical and histological studies. (7185021)
1982
46
Using a bandage contact lens to prevent recurrent corneal erosion during photocoagulation in patients with diabetes. (7197882)
1981
47
Treatment of recurrent corneal erosion and corneal edema with topical osmotic colloidal solution. (6172765)
1981
48
Inherited recurrent corneal erosion. (6985236)
1981
49
Recurrent corneal erosion: pathogenesis and therapy. (110716)
1979
50
Recurrent corneal erosion. (4544649)
1973

Variations for Recurrent Corneal Erosion

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Expression for genes affiliated with Recurrent Corneal Erosion

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Search GEO for disease gene expression data for Recurrent Corneal Erosion.

Pathways for genes affiliated with Recurrent Corneal Erosion

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Pathways related to Recurrent Corneal Erosion according to GeneCards Suite gene sharing:

(show all 36)
idSuper pathwaysScoreTop Affiliating Genes
19.5IL1B, IL6
29.5IL1B, IL6
39.5IL1B, IL6
49.5IL1B, IL6
59.5IL1B, IL6
6
Show member pathways
9.5IL1B, IL6
79.5IL1B, IL6
89.5IL1B, IL6
99.5IL1B, IL6
109.3CXCL8, IL6
119.3CXCL8, IL6
129.3CXCL8, IL6
139.3CXCL8, IL6
149.3CXCL8, IL6
159.3CXCL8, IL6
168.9CXCL8, IL1B, IL6
17
Show member pathways
8.9CXCL8, IL1B, IL6
188.9CXCL8, IL1B, IL6
198.9CXCL8, IL1B, IL6
20
Show member pathways
8.9CXCL8, IL1B, IL6
21
Show member pathways
8.9CXCL8, IL1B, IL6
228.9CXCL8, IL1B, IL6
238.9CXCL8, IL1B, IL6
24
Show member pathways
8.9CXCL8, IL1B, IL6
25
Show member pathways
8.9CXCL8, IL1B, IL6
26
Show member pathways
8.9CXCL8, IL1B, IL6
27
Show member pathways
8.9CXCL8, IL1B, IL6
28
Show member pathways
8.9CXCL8, IL1B, IL6
298.9CXCL8, IL1B, IL6
308.9CXCL8, IL1B, IL6
31
Show member pathways
8.9CXCL8, IL1B, IL6
328.9CXCL8, IL1B, IL6
338.9CXCL8, IL1B, IL6
348.9CXCL8, IL1B, IL6
35
Show member pathways
8.9CXCL8, IL1B, IL6
36
Show member pathways
8.9CXCL8, IL1B, IL6

GO Terms for genes affiliated with Recurrent Corneal Erosion

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Cellular components related to Recurrent Corneal Erosion according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.8CXCL8, IL1B, IL6, TGFBI
2extracellular spaceGO:00056157.5CXCL8, DNAJC9, IL1B, IL6, TGFBI

Biological processes related to Recurrent Corneal Erosion according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interleukin-6 productionGO:00327559.9IL1B, IL6
2neutrophil chemotaxisGO:00305939.8CXCL8, IL1B
3positive regulation of neutrophil chemotaxisGO:00900239.8CXCL8, IL1B
4cellular response to interleukin-1GO:00713479.8CXCL8, IL6
5positive regulation of nitric oxide biosynthetic processGO:00454299.7IL1B, IL6
6positive regulation of T cell proliferationGO:00421029.7IL1B, IL6
7response to heatGO:00094089.6IL1B, IL6
8social behaviorGO:00351769.5DNAJC9, IL1B
9inflammatory responseGO:00069549.2CXCL8, IL1B, IL6
10negative regulation of cell proliferationGO:00082858.8CXCL8, IL1B, IL6

Sources for Recurrent Corneal Erosion

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet