MCID: RCR001
MIFTS: 35

Recurrent Corneal Erosion malady

Category: Eye diseases

Aliases & Classifications for Recurrent Corneal Erosion

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Aliases & Descriptions for Recurrent Corneal Erosion:

Name: Recurrent Corneal Erosion 10 12
Recurrent Erosion of Cornea 10 65
 
Recurrent Erosion Syndrome 10

Classifications:



External Ids:

Disease Ontology10 DOID:11541
ICD1027 H18.83
ICD9CM29 371.42
UMLS65 C0155119

Summaries for Recurrent Corneal Erosion

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Wikipedia:68 Recurrent corneal erosion is a disorder of the eyes characterized by the failure of the cornea\'s... more...

MalaCards based summary: Recurrent Corneal Erosion, also known as recurrent erosion of cornea, is related to lateral sclerosis and endocarditis. An important gene associated with Recurrent Corneal Erosion is IL1B (Interleukin 1 Beta), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and African trypanosomiasis. Affiliated tissues include eye, heart and spinal cord.

Related Diseases for Recurrent Corneal Erosion

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Diseases related to Recurrent Corneal Erosion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 204)
idRelated DiseaseScoreTop Affiliating Genes
1lateral sclerosis30.5IL1B, IL6
2endocarditis30.4CXCL8, IL6
3optic neuritis30.1CXCL8, IL1B, IL6
4epithelial recurrent erosion dystrophy11.6
5corneal dystrophy, avellino type10.5
6corneal dystrophy, lattice type iiia10.5
7primary lacrimal atrophy10.3CXCL8, IL1B
8testicular granulosa cell tumor10.3CXCL8, IL1B
9wells-jankovic syndrome10.3CXCL8, IL1B
10auricular cancer10.3CXCL8, IL1B
11peripheral retinal degeneration10.3CXCL8, IL1B
12gonadal disease10.3CXCL8, IL1B
13mammary paget's disease10.3IL1B, IL6
14lujo hemorrhagic fever10.3IL1B, IL6
15hemoglobin c disease10.3IL1B, IL6
16residual stage angle-closure glaucoma10.3IL1B, IL6
17mansonelliasis10.3CXCL8, IL1B
18ileitis10.3IL1B, TGFBI
19granulomatous amebic encephalitis10.3IL1B, IL6
20refractory plasma cell neoplasm10.3IL1B, IL6
21chronic monocytic leukemia10.3IL1B, IL6
22skin conditions10.3IL1B, IL6
23infiltrating bladder lymphoepithelioma-like carcinoma10.3CXCL8, IL1B
24postsurgical hypothyroidism10.3IL1B, IL6
25ulcer of lower limbs10.3IL1B, IL6
26human granulocytic anaplasmosis10.3IL1B, IL6
27rubeosis iridis10.3IL1B, IL6
28ureteral disease10.3IL1B, IL6
29large intestine lipoma10.3IL1B, IL6
30duodenum cancer10.3IL1B, IL6
31balantidiasis10.3CXCL8, IL1B
32malignant sertoli-leydig cell tumor of ovary10.3CXCL8, IL6
33cystic echinococcosis10.3IL1B, IL6
34pediatric infratentorial ependymoma10.3CXCL8, IL1B
35idiopathic spinal cord herniation10.3IL1B, IL6
36dentin caries10.3IL1B, IL6
37single ventricular heart10.3CXCL8, IL1B
38placental abruption10.3IL1B, IL6
39osteogenesis imperfecta, type x10.3CXCL8, IL6
40secretory diarrhea10.3IL1B, IL6
41meige syndrome10.2IL1B, IL6
42critical illness polyneuropathy10.2CXCL8, IL6
43submandibular gland disease10.2IL1B, IL6
44retromolar area cancer10.2CXCL8, IL1B
45tracheal stenosis10.2IL1B, IL6
46tick-borne relapsing fever10.2CXCL8, IL6
47hypoglycemic coma10.2CXCL8, IL1B
48narcissistic personality disorder10.2CXCL8, IL6
49scrotum squamous cell carcinoma10.2CXCL8, IL6
50blue toe syndrome10.2CXCL8, IL6

Graphical network of the top 20 diseases related to Recurrent Corneal Erosion:



Diseases related to recurrent corneal erosion

Symptoms for Recurrent Corneal Erosion

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Drugs & Therapeutics for Recurrent Corneal Erosion

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Drugs for Recurrent Corneal Erosion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Ophthalmic SolutionsPhase 41006
2TetrahydrozolinePhase 4542
3Pharmaceutical Solutions7004
4Lubricant Eye Drops153
5Dextrans72

Interventional clinical trials:

idNameStatusNCT IDPhase
1Phototherapeutic Keratectomy (PTK) on Recurrent Corneal ErosionsCompletedNCT01251692Phase 4
2Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic KeratectomyRecruitingNCT02373397Phase 4
3Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG LaserCompletedNCT00816738
4Umbilical Cord Serum Eye DropsCompletedNCT01016158
5Study of Dehydrex in Patients With Corneal ErosionCompletedNCT00029185

Search NIH Clinical Center for Recurrent Corneal Erosion

Genetic Tests for Recurrent Corneal Erosion

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Anatomical Context for Recurrent Corneal Erosion

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MalaCards organs/tissues related to Recurrent Corneal Erosion:

33
Eye, Heart, Spinal cord, Lung, Breast, Endothelial, Neutrophil

Animal Models for Recurrent Corneal Erosion or affiliated genes

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Publications for Recurrent Corneal Erosion

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Articles related to Recurrent Corneal Erosion:

(show top 50)    (show all 76)
idTitleAuthorsYear
1
Senescence is involved in the pathogenesis of chronic obstructive pulmonary disease through effects on telomeres and the anti-aging molecule fibroblast growth factora8823. (25257970)
2015
2
Association of extended interleukin-10 promoter haplotypes with disease susceptibility and manifestations in German patients with systemic lupus erythematosus. (24536045)
2014
3
Molecular findings in Beckwith-Wiedemann syndrome. (23592339)
2013
4
Unique X-linked familial FSGS with co-segregating heart block disorder is associated with a mutation in the NXF5 gene. (23686279)
2013
5
Experiences with Spinal Cord Stimulator in Patients with Chronic Neuropathic Back Pain. (24001570)
2013
6
Association between PRO12ALA polymorphism of the PPAR-I^2 gene and type 2 diabetes mellitus in Iranian patients. (24019628)
2013
7
Serum visfatin levels do not increase in post-menopausal women with metabolic syndrome. (23538464)
2013
8
WaldenstrAPm's macroglobulinaemia complicated by pure red cell aplasia: a case report. (23736934)
2013
9
Genetic susceptibility to otitis media in childhood. (22252840)
2012
10
Differential transcription factor use by the KIR2DL4 promoter under constitutive and IL-2/15-treated conditions. (22467658)
2012
11
Pulmonary diffusing capacity for carbon monoxide: a marker of depressed hypercapnic drive in type 1 diabetes mellitus? (22004301)
2011
12
Spinal neurosarcoidosis. (21739394)
2011
13
Sheehan syndrome in Costa Rica: clinical experience with 60 cases. (21041170)
2011
14
Clinical trial of 0.02% polyhexamethylene biguanide versus placebo in the treatment of microsporidial keratoconjunctivitis. (21163375)
2011
15
Early non-adherence to medication and other risk factors for rehospitalization in schizophrenia and schizoaffective disorder. (21982098)
2011
16
Clopidogrel Resistance: case reports of CYP2C19 gene variants in suspected coronary stent thrombosis. (21215696)
2011
17
Retinal microvascular signs and 10-year risk of cerebral atrophy: the Atherosclerosis Risk in Communities (ARIC) study. (20576949)
2010
18
Evolving treatment paradigms for acute cholecystitis: comment on "Surgical management of acute cholecystitis at a tertiary care center in the modern era". (20491161)
2010
19
Disease-free interval after primary treatment predicts prognosis of recurrent endometrial carcinoma. (21036762)
2010
20
Collagen cross-linking by adipose-derived mesenchymal stromal cells and scar-derived mesenchymal cells: Are mesenchymal stromal cells involved in scar formation? (19614920)
2009
21
Our 21-year experience with the Thiersch-Duplay technique following surgical correction of penoscrotal transposition. (19172093)
2009
22
O-GlcNAc modification of Sp1 inhibits the functional interaction between Sp1 and Oct1. (19070619)
2009
23
High throughput, parallel imaging and biomarker quantification of human spermatozoa by ImageStream flow cytometry. (19938959)
2009
24
Mechanisms of the anti-inflammatory effects of hydroxyethyl starch demonstrated in a flow-based model of neutrophil recruitment by endothelial cells. (18434912)
2008
25
Rare CBFB-MYH11 fusion transcripts in AML with inv(16)/t(16;16) are associated with therapy-related AML M4eo, atypical cytomorphology, atypical immunophenotype, atypical additional chromosomal rearrangements and low white blood cell count: a study on 162 patients. (17287858)
2007
26
Course and outcome of acute limbic encephalitis with negative voltage-gated potassium channel antibodies. (17098840)
2007
27
Congenital syphilis presenting as swelling of fingers and toes. (17822178)
2007
28
The "reversible" dementia of idiopathic normal pressure hydrocephalus. (17243853)
2006
29
Adapting to AL amyloidosis. (17145594)
2006
30
Clinical study on effect of tongluo capsule in treating diabetic nephropathy caused chronic renal failure]. (15366593)
2004
31
Micropuncture cholecystectomy vs conventional laparoscopic cholecystectomy: a randomized controlled trial. (12618946)
2003
32
Dopamine D4 receptor and tyrosine hydroxylase genes in bipolar disorder: evidence for a role of DRD4. (12232779)
2002
33
Analysis of hepatocellular carcinoma tumor growth detected in sustained responders to interferon in patients with chronic hepatitis C. (11686840)
2001
34
Intestinal microsporidiosis in HIV-infected children with acute and chronic diarrhea. (11485091)
2001
35
Modulation of cytochrome P4501-mediated bioactivation of benzo[a]pyrene by volatile allyl sulfides in human hepatoma cells. (11758911)
2001
36
Human and other faeces as breeding media of the trachoma vector Musca sorbens. (11583450)
2001
37
Acute (ascending) cholangitis. (10987108)
2000
38
Optimising methods for determining RER status in colorectal cancers. (10737703)
2000
39
Intra-alveolar urinary trypsin inhibitor cannot inhibit polymorphonuclear elastase activity in the lung in postsurgical patients with acute respiratory distress syndrome. (10554326)
1999
40
Preclinical primary central nervous system lymphoma. (9101110)
1997
41
Basilar artery occlusion associated with anabolic steroid abuse in a 17-year-old bodybuilder. (9137931)
1997
42
Interplanetary travel and permanent injury to normal heart. (11543600)
1997
43
Synthesis of type 1 (IFN gamma) and type 2 (IL-4, IL-5, and IL-10) cytokines by human eosinophils. (8906227)
1996
44
GPA and CNTF produce similar effects in sympathetic neurones but differ in receptor binding. (8298104)
1993
45
Drug metabolism in end-stage liver disease. In vitro activities of some phase I and phase II enzymes. (2398265)
1990
46
Renal effects of angiotensin-converting enzyme inhibition in congestive heart failure. (2220600)
1990
47
Diffuse alveolar hemorrhage temporally related to cocaine smoking. (3338316)
1988
48
Cloning of a complementary deoxyribonucleic acid coding for human thyroxine-binding globulin (TBG): existence of two TBG messenger ribonucleic acid species possessing different 3'-untranslated regions. (2969453)
1988
49
Periodic hyperammonemia, hyperlysinemia, and homocitrullinuria associated with decreased argininosuccinate synthetase and arginase activities. (904980)
1977
50
The relationship of vesico-ureteric reflux to urinary tract infection and chronic pyelonephritis-reflux nephropathy. (4783715)
1973

Variations for Recurrent Corneal Erosion

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Expression for genes affiliated with Recurrent Corneal Erosion

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Search GEO for disease gene expression data for Recurrent Corneal Erosion.

Pathways for genes affiliated with Recurrent Corneal Erosion

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Pathways related to Recurrent Corneal Erosion according to GeneCards Suite gene sharing:

(show all 27)
idSuper pathwaysScoreTop Affiliating Genes
19.5IL1B, IL6
29.5IL1B, IL6
39.5IL1B, IL6
49.5IL1B, IL6
59.5IL1B, IL6
69.5IL1B, IL6
79.5CXCL8, IL6
89.5CXCL8, IL6
99.5CXCL8, IL6
109.5CXCL8, IL6
119.5CXCL8, IL6
12
Show member pathways
9.1CXCL8, IL1B, IL6
13
Show member pathways
9.1CXCL8, IL1B, IL6
14
Show member pathways
9.1CXCL8, IL1B, IL6
15
Show member pathways
9.1CXCL8, IL1B, IL6
16
Show member pathways
9.1CXCL8, IL1B, IL6
179.1CXCL8, IL1B, IL6
189.1CXCL8, IL1B, IL6
199.1CXCL8, IL1B, IL6
209.1CXCL8, IL1B, IL6
219.1CXCL8, IL1B, IL6
229.1CXCL8, IL1B, IL6
239.1CXCL8, IL1B, IL6
24
Show member pathways
9.1CXCL8, IL1B, IL6
25
Show member pathways
9.1CXCL8, IL1B, IL6
269.1CXCL8, IL1B, IL6
279.1CXCL8, IL1B, IL6

GO Terms for genes affiliated with Recurrent Corneal Erosion

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Biological processes related to Recurrent Corneal Erosion according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of nitric oxide biosynthetic processGO:004542910.1IL1B, IL6
2response to glucocorticoidGO:005138410.0IL1B, IL6
3positive regulation of neutrophil chemotaxisGO:009002310.0CXCL8, IL1B
4wound healingGO:004206010.0IL1B, IL6
5positive regulation of sequence-specific DNA binding transcription factor activityGO:005109110.0IL1B, IL6
6neutrophil chemotaxisGO:00305939.9CXCL8, IL1B
7positive regulation of ERK1 and ERK2 cascadeGO:00703749.8IL1B, IL6
8positive regulation of interleukin-6 productionGO:00327559.7IL1B, IL6
9positive regulation of apoptotic processGO:00430659.7IL1B, IL6
10response to heatGO:00094089.5IL1B, IL6
11cellular response to tumor necrosis factorGO:00713569.2CXCL8, IL6
12immune responseGO:00069559.1CXCL8, IL1B, IL6
13cellular response to lipopolysaccharideGO:00712229.0CXCL8, IL1B, IL6

Sources for Recurrent Corneal Erosion

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet