MCID: RCR001
MIFTS: 40

Recurrent Corneal Erosion malady

Category: Eye diseases

Aliases & Classifications for Recurrent Corneal Erosion

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Aliases & Descriptions for Recurrent Corneal Erosion:

Name: Recurrent Corneal Erosion 10 12
Recurrent Erosion of Cornea 10 65
 
Recurrent Erosion Syndrome 10

Classifications:



External Ids:

Disease Ontology10 DOID:11541
ICD1027 H18.83
ICD9CM29 371.42
UMLS65 C0155119

Summaries for Recurrent Corneal Erosion

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Wikipedia:68 Recurrent corneal erosion is a disorder of the eyes characterized by the failure of the cornea\'s... more...

MalaCards based summary: Recurrent Corneal Erosion, also known as recurrent erosion of cornea, is related to epithelial recurrent erosion dystrophy and primary lacrimal atrophy. An important gene associated with Recurrent Corneal Erosion is IL1B (Interleukin 1 Beta), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and African trypanosomiasis. Affiliated tissues include eye, breast and spinal cord.

Related Diseases for Recurrent Corneal Erosion

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Diseases related to Recurrent Corneal Erosion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 151)
idRelated DiseaseScoreTop Affiliating Genes
1epithelial recurrent erosion dystrophy11.2
2primary lacrimal atrophy10.5CXCL8, IL1B
3testicular granulosa cell tumor10.5CXCL8, IL1B
4wells-jankovic syndrome10.5CXCL8, IL1B
5auricular cancer10.5CXCL8, IL1B
6peripheral retinal degeneration10.5CXCL8, IL1B
7gonadal disease10.5CXCL8, IL1B
8mammary paget's disease10.4IL1B, IL6
9lujo hemorrhagic fever10.4IL1B, IL6
10hemoglobin c disease10.4IL1B, IL6
11residual stage angle-closure glaucoma10.4IL1B, IL6
12mansonelliasis10.4CXCL8, IL1B
13ileitis10.4IL1B, TGFBI
14granulomatous amebic encephalitis10.4IL1B, IL6
15refractory plasma cell neoplasm10.4IL1B, IL6
16chronic monocytic leukemia10.4IL1B, IL6
17skin conditions10.4IL1B, IL6
18infiltrating bladder lymphoepithelioma-like carcinoma10.4CXCL8, IL1B
19postsurgical hypothyroidism10.4IL1B, IL6
20ulcer of lower limbs10.4IL1B, IL6
21human granulocytic anaplasmosis10.4IL1B, IL6
22rubeosis iridis10.4IL1B, IL6
23ureteral disease10.4IL1B, IL6
24large intestine lipoma10.4IL1B, IL6
25duodenum cancer10.4IL1B, IL6
26balantidiasis10.4CXCL8, IL1B
27malignant sertoli-leydig cell tumor of ovary10.4CXCL8, IL6
28cystic echinococcosis10.4IL1B, IL6
29pediatric infratentorial ependymoma10.4CXCL8, IL1B
30idiopathic spinal cord herniation10.4IL1B, IL6
31dentin caries10.4IL1B, IL6
32single ventricular heart10.4CXCL8, IL1B
33placental abruption10.4IL1B, IL6
34osteogenesis imperfecta, type x10.4CXCL8, IL6
35secretory diarrhea10.4IL1B, IL6
36meige syndrome10.4IL1B, IL6
37critical illness polyneuropathy10.4CXCL8, IL6
38submandibular gland disease10.4IL1B, IL6
39retromolar area cancer10.4CXCL8, IL1B
40tracheal stenosis10.4IL1B, IL6
41lateral sclerosis10.4IL1B, IL6
42tick-borne relapsing fever10.4CXCL8, IL6
43hypoglycemic coma10.4CXCL8, IL1B
44narcissistic personality disorder10.4CXCL8, IL6
45scrotum squamous cell carcinoma10.4CXCL8, IL6
46blue toe syndrome10.4CXCL8, IL6
47endocarditis10.4CXCL8, IL6
48aggressive digital papillary adenocarcinoma10.3CXCL8, IL6
49intervertebral disc disease10.3IL1B, IL6
50psychologic dyspareunia10.3CXCL8, IL6

Graphical network of the top 20 diseases related to Recurrent Corneal Erosion:



Diseases related to recurrent corneal erosion

Symptoms for Recurrent Corneal Erosion

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Drugs & Therapeutics for Recurrent Corneal Erosion

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Drugs for Recurrent Corneal Erosion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Ophthalmic SolutionsPhase 41006
2TetrahydrozolinePhase 4542
3Pharmaceutical Solutions7004
4Lubricant Eye Drops153
5Dextrans72

Interventional clinical trials:

idNameStatusNCT IDPhase
1Phototherapeutic Keratectomy (PTK) on Recurrent Corneal ErosionsCompletedNCT01251692Phase 4
2Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic KeratectomyRecruitingNCT02373397Phase 4
3Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG LaserCompletedNCT00816738
4Umbilical Cord Serum Eye DropsCompletedNCT01016158
5Study of Dehydrex in Patients With Corneal ErosionCompletedNCT00029185

Search NIH Clinical Center for Recurrent Corneal Erosion

Genetic Tests for Recurrent Corneal Erosion

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Anatomical Context for Recurrent Corneal Erosion

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MalaCards organs/tissues related to Recurrent Corneal Erosion:

33
Eye, Breast, Spinal cord, Heart, Liver, B cells, Endothelial

Animal Models for Recurrent Corneal Erosion or affiliated genes

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Publications for Recurrent Corneal Erosion

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Articles related to Recurrent Corneal Erosion:

(show top 50)    (show all 78)
idTitleAuthorsYear
1
Recurrent corneal erosion syndrome associated with oral isotretinoin: a cautionary tale. (26932827)
2016
2
Superior Perilimbal Epitheliopathy in Recurrent Corneal Erosion Syndrome. (26203756)
2015
3
Long-Term Outcomes of Epithelial Debridement and Diamond Burr Polishing for Corneal Epithelial Irregularity and Recurrent Corneal Erosion. (26203746)
2015
4
Phototherapeutic keratectomy (PTK) for treatment of recurrent corneal erosion: Correlation between etiology and prognosis - prospective longitudinal study. (25900814)
2015
5
Authors' response: A randomised controlled trial of alcohol delamination and phototherapeutic keratectomy for the treatment of recurrent corneal erosion syndrome. (24352600)
2014
6
A randomised controlled trial of alcohol delamination and phototherapeutic keratectomy for the treatment of recurrent corneal erosion syndrome. (23759442)
2014
7
Clinical presentation and causes of recurrent corneal erosion syndrome: review of 100 patients. (24699561)
2014
8
Authors' response: A randomised controlled trial of alcohol delamination and phototherapeutic keratectomy for the treatment of recurrent corneal erosion syndrome. (24352599)
2014
9
Epithelial debridement with diamond burr superficial keratectomy for the treatment of recurrent corneal erosion. (23230823)
2013
10
Lubricants to prevent recurrent corneal erosion: an error in the Cochrane review. (23989120)
2013
11
Changes of clinical manifestation of granular corneal deposits because of recurrent corneal erosion in granular corneal dystrophy types 1 and 2. (23132456)
2013
12
IL1beta, IL6 and IL8 gene polymorphisms involvement in recurrent corneal erosion in patients with hereditary stromal corneal dystrophies. (23821953)
2013
13
Recurrent Corneal Erosion Syndrome. (26107728)
2012
14
Recurrent corneal erosion following uneventful IntraLASIK treated by phototherapeutic keratectomy. (22180150)
2012
15
Franceschetti hereditary recurrent corneal erosion. (22402249)
2012
16
Treatment of recurrent corneal erosion by extended-wear bandage contact lens. (20847650)
2011
17
Recurrent Corneal Erosion Syndrome: A Study of 364 Episodes. (20337327)
2010
18
Corneal re-epithelialization following phototherapeutic keratectomy for recurrent corneal erosion as in vivo model of epithelial wound healing. (19648776)
2009
19
Treatment of recurrent corneal erosion syndrome using the combination of oral doxycycline and topical corticosteroid. (18290949)
2008
20
In vivo biopsy by laser confocal microscopy for evaluation of traumatic recurrent corneal erosion. (19093010)
2008
21
Recurrent corneal erosion syndrome. (19026329)
2008
22
Recurrent corneal erosion syndrome. (18191654)
2008
23
Recurrent corneal erosion. (17908600)
2007
24
Small spot phototherapeutic keratectomy for recurrent corneal erosion. (17912944)
2007
25
Alcohol delamination of the corneal epithelium for recalcitrant recurrent corneal erosion syndrome: a prospective study of efficacy and safety. (17301117)
2007
26
Recurrent corneal erosion: characteristics and management options. (18306941)
2007
27
Long-term efficacy of phototherapeutic keratectomy on recurrent corneal erosion syndrome. (17172888)
2006
28
Successful management of three consecutive cases of recurrent corneal erosion with botulinum toxin injections. (14765101)
2004
29
Anterior basement membrane corneal dystrophy and pseudo-unilateral lattice corneal dystrophy in a patient with recurrent corneal erosions. (15183802)
2004
30
Anterior stromal puncture for recurrent corneal erosion after laser in situ keratomileusis. (15030848)
2004
31
Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids. (11438047)
2001
32
Matrix metalloproteinases in epithelia from human recurrent corneal erosion. (10235563)
1999
33
Recurrent corneal erosion syndrome. (10535864)
1999
34
Combined PRK and PTK in myopic patients with recurrent corneal erosion. (9290367)
1997
35
Corneal topographic lagoons: a potential new marker for post-traumatic recurrent corneal erosion syndrome. (8743001)
1996
36
The natural history and management of recurrent corneal erosion: a prospective randomised trial. (8013716)
1994
37
Excimer laser phototherapeutic keratectomy for treatment of recurrent corneal erosion. (8201570)
1994
38
Recurrent corneal erosion: clinical features. (7821454)
1994
39
Successful treatment of recurrent corneal erosion with Nd:YAG anterior stromal puncture. (2220975)
1990
40
Recurrent corneal erosion. (2803088)
1989
41
Non-traumatic recurrent corneal erosion. A study based on sequential photomacrographic recordings. (3501223)
1987
42
The treatment of recurrent corneal erosion. (3820505)
1987
43
Recurrent corneal erosion, microcystic epithelial dystrophy, map configurations and fingerprint lines in the cornea. (3490898)
1986
44
Recurrent corneal erosion after trauma: a statistical study. (4062156)
1985
45
Posttraumatic recurrent corneal erosion, #2. Ultrastructural findings in epithelium and stroma. (6621361)
1983
46
Posttraumatic recurrent corneal erosion. 1. Clinical and histological studies. (7185021)
1982
47
Inherited recurrent corneal erosion. (6985236)
1981
48
Using a bandage contact lens to prevent recurrent corneal erosion during photocoagulation in patients with diabetes. (7197882)
1981
49
Treatment of recurrent corneal erosion and corneal edema with topical osmotic colloidal solution. (6172765)
1981
50
Recurrent corneal erosion. (4544649)
1973

Variations for Recurrent Corneal Erosion

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Expression for genes affiliated with Recurrent Corneal Erosion

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Search GEO for disease gene expression data for Recurrent Corneal Erosion.

Pathways for genes affiliated with Recurrent Corneal Erosion

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Pathways related to Recurrent Corneal Erosion according to GeneCards Suite gene sharing:

(show all 27)
idSuper pathwaysScoreTop Affiliating Genes
19.5IL1B, IL6
29.5IL1B, IL6
39.5IL1B, IL6
49.5IL1B, IL6
59.5IL1B, IL6
69.5IL1B, IL6
79.5CXCL8, IL6
89.5CXCL8, IL6
99.5CXCL8, IL6
109.5CXCL8, IL6
119.5CXCL8, IL6
12
Show member pathways
9.1CXCL8, IL1B, IL6
13
Show member pathways
9.1CXCL8, IL1B, IL6
14
Show member pathways
9.1CXCL8, IL1B, IL6
15
Show member pathways
9.1CXCL8, IL1B, IL6
16
Show member pathways
9.1CXCL8, IL1B, IL6
179.1CXCL8, IL1B, IL6
189.1CXCL8, IL1B, IL6
199.1CXCL8, IL1B, IL6
209.1CXCL8, IL1B, IL6
219.1CXCL8, IL1B, IL6
229.1CXCL8, IL1B, IL6
239.1CXCL8, IL1B, IL6
24
Show member pathways
9.1CXCL8, IL1B, IL6
25
Show member pathways
9.1CXCL8, IL1B, IL6
269.1CXCL8, IL1B, IL6
279.1CXCL8, IL1B, IL6

GO Terms for genes affiliated with Recurrent Corneal Erosion

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Biological processes related to Recurrent Corneal Erosion according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of nitric oxide biosynthetic processGO:004542910.1IL1B, IL6
2response to glucocorticoidGO:005138410.0IL1B, IL6
3positive regulation of neutrophil chemotaxisGO:009002310.0CXCL8, IL1B
4wound healingGO:004206010.0IL1B, IL6
5positive regulation of sequence-specific DNA binding transcription factor activityGO:005109110.0IL1B, IL6
6neutrophil chemotaxisGO:00305939.9CXCL8, IL1B
7positive regulation of ERK1 and ERK2 cascadeGO:00703749.8IL1B, IL6
8positive regulation of interleukin-6 productionGO:00327559.7IL1B, IL6
9positive regulation of apoptotic processGO:00430659.7IL1B, IL6
10response to heatGO:00094089.5IL1B, IL6
11cellular response to tumor necrosis factorGO:00713569.2CXCL8, IL6
12immune responseGO:00069559.1CXCL8, IL1B, IL6
13cellular response to lipopolysaccharideGO:00712229.0CXCL8, IL1B, IL6

Sources for Recurrent Corneal Erosion

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet