Recurrent Respiratory Papillomatosis (RRP) malady

NIH Rare Diseases:⁴² Recurrent respiratory papillomatosis (rrp) is a rare viral disease where tumors (papillomas) grow in the air passages leading from the nose and mouth into the lungs (respiratory tract). although the tumors can grow anywhere in the respiratory tract, their presence in the larynx (voice box) causes the most frequent problems, a condition called laryngeal papillomatosis. the tumors may vary in size and grow very quickly. they often grow back even when removed. rrp is caused by two types of human papillomavirus (hpv), called hpv 6 and hpv 11. last updated: 11/21/2011

MalaCards based summary: Recurrent Respiratory Papillomatosis, also known as juvenile-onset recurrent respiratory papillomatosis, is related to papilloma and laryngitis. An important gene associated with Recurrent Respiratory Papillomatosis is KIR2DL5A (killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A), and among its related pathways are Class I MHC mediated antigen processing and presentation and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. The compound mannose have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and t cells.

Wikipedia:⁶⁴ Laryngeal papillomatosis, also known as recurrent respiratory papillomatosis or glottal papillomatosis,... more...

External Ids:

MESH via Orphanet35 C535297

UMLS via Orphanet62 C1168198

Search GEO for disease gene expression data for Recurrent Respiratory Papillomatosis.