MCID: RDG002
MIFTS: 20

Red-Green Color Vision Defects

Categories: Genetic diseases, Eye diseases

Aliases & Classifications for Red-Green Color Vision Defects

MalaCards integrated aliases for Red-Green Color Vision Defects:

Name: Red-Green Color Vision Defects 24
Color Blindness 24 69

Classifications:



Summaries for Red-Green Color Vision Defects

MalaCards based summary : Red-Green Color Vision Defects, also known as color blindness, is related to color blindness and color vision deficiency, and has symptoms including other specified visual disturbances, subjective visual disturbance, unspecified and visual disturbance. An important gene associated with Red-Green Color Vision Defects is OPN1MW (Opsin 1, Medium Wave Sensitive), and among its related pathways/superpathways are Metabolism of fat-soluble vitamins and Retinoid cycle disease events. Related phenotype is Decreased shRNA abundance (Z-score < -2).

Related Diseases for Red-Green Color Vision Defects

Diseases related to Red-Green Color Vision Defects via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 color blindness 11.1
2 color vision deficiency 11.1
3 renal tubular dysgenesis, agtr1-related 9.7 OPN1LW OPN1MW
4 core binding factor acute myeloid leukemia 9.7 OPN1LW OPN1MW
5 somatization disorder 9.6 OPN1LW OPN1MW
6 lumbosacral plexus lesion 9.6 OPN1LW OPN1MW
7 waisman syndrome 9.5 OPN1LW OPN1MW
8 acute biphenotypic leukemia 9.5 OPN1LW OPN1MW
9 angioid streaks 9.4 OPN1LW OPN1MW
10 androgenic alopecia 9.2 OPN1LW OPN1MW

Graphical network of the top 20 diseases related to Red-Green Color Vision Defects:



Diseases related to Red-Green Color Vision Defects

Symptoms & Phenotypes for Red-Green Color Vision Defects

UMLS symptoms related to Red-Green Color Vision Defects:


other specified visual disturbances, subjective visual disturbance, unspecified, visual disturbance

GenomeRNAi Phenotypes related to Red-Green Color Vision Defects according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-112 9.56 OPN1MW OPN1LW
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 9.56 OPN1MW
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-14 9.56 OPN1LW
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-209 9.56 OPN1MW
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-28 9.56 OPN1MW
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-62 9.56 OPN1MW
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 9.56 OPN1LW
8 Increased circadian period length GR00213-A 8.62 OPN1LW OPN1MW

Drugs & Therapeutics for Red-Green Color Vision Defects

Search Clinical Trials , NIH Clinical Center for Red-Green Color Vision Defects

Genetic Tests for Red-Green Color Vision Defects

Genetic tests related to Red-Green Color Vision Defects:

id Genetic test Affiliating Genes
1 Red-Green Color Vision Defects 24 OPN1LW OPN1MW

Anatomical Context for Red-Green Color Vision Defects

Publications for Red-Green Color Vision Defects

Articles related to Red-Green Color Vision Defects:

id Title Authors Year
1
Prevalence of Red-Green Color Vision Defects among Muslim Males and Females of Manipur, India. ( 23515069 )
2013
2
Topographical cone photopigment gene expression in deutan-type red-green color vision defects. ( 14637363 )
2004
3
Prevalence of congenital red-green color vision defects in Arab boys from Riyadh, Saudi Arabia. ( 8956321 )
1996
4
Red-Green Color Vision Defects ( 20301478 )
1993
5
Genotype-phenotype relationships in human red/green color-vision defects: molecular and psychophysical studies. ( 1415215 )
1992

Variations for Red-Green Color Vision Defects

Expression for Red-Green Color Vision Defects

Search GEO for disease gene expression data for Red-Green Color Vision Defects.

Pathways for Red-Green Color Vision Defects

Pathways related to Red-Green Color Vision Defects according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.49 OPN1LW OPN1MW
2
Show member pathways
10.23 OPN1LW OPN1MW
3 9.58 OPN1LW OPN1MW

GO Terms for Red-Green Color Vision Defects

Cellular components related to Red-Green Color Vision Defects according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 photoreceptor outer segment GO:0001750 8.96 OPN1LW OPN1MW
2 photoreceptor disc membrane GO:0097381 8.62 OPN1LW OPN1MW

Biological processes related to Red-Green Color Vision Defects according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to stimulus GO:0050896 9.37 OPN1LW OPN1MW
2 visual perception GO:0007601 9.32 OPN1LW OPN1MW
3 retinoid metabolic process GO:0001523 9.26 OPN1LW OPN1MW
4 positive regulation of cytokinesis GO:0032467 9.16 OPN1LW OPN1MW
5 phototransduction GO:0007602 8.96 OPN1LW OPN1MW
6 protein-chromophore linkage GO:0018298 8.62 OPN1LW OPN1MW

Molecular functions related to Red-Green Color Vision Defects according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 G-protein coupled receptor activity GO:0004930 9.16 OPN1LW OPN1MW
2 signal transducer activity GO:0004871 8.96 OPN1LW OPN1MW
3 photoreceptor activity GO:0009881 8.62 OPN1LW OPN1MW

Sources for Red-Green Color Vision Defects

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....