Aliases & Classifications for Reflex Epilepsy

MalaCards integrated aliases for Reflex Epilepsy:

Name: Reflex Epilepsy 12 14
Epilepsy, Reflex 42 69
Epilepsy, Sensory-Induced 12
Epilepsy Reflex 52

Classifications:



External Ids:

Disease Ontology 12 DOID:2548
MeSH 42 D020195
NCIt 47 C85041
SNOMED-CT 64 79745005
UMLS 69 C0270857

Summaries for Reflex Epilepsy

MalaCards based summary : Reflex Epilepsy, also known as epilepsy, reflex, is related to genetic reflex epilepsy and hot water reflex epilepsy, and has symptoms including seizures An important gene associated with Reflex Epilepsy is WARS (Tryptophanyl-TRNA Synthetase). The drugs Valproic Acid and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, thalamus and temporal lobe.

Related Diseases for Reflex Epilepsy

Diseases related to Reflex Epilepsy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
id Related Disease Score Top Affiliating Genes
1 genetic reflex epilepsy 12.0
2 hot water reflex epilepsy 11.9
3 epilepsy 10.6
4 erythermalgia, primary 9.9 TBC1D24 WARS
5 photosensitive epilepsy 9.8
6 hyperglycemia 9.7
7 athetosis 9.7
8 early onset absence epilepsy 9.6 TBC1D24 WARS
9 cerebellar hypoplasia 9.6
10 cerebritis 9.6
11 glioma 9.6
12 myoclonus 9.6
13 paroxysmal choreoathetosis 9.6
14 relapsing polychondritis 7.4 ADORA3 IL1RAPL1 NDRG4 PGLYRP3 TBC1D24 WARS

Graphical network of the top 20 diseases related to Reflex Epilepsy:



Diseases related to Reflex Epilepsy

Symptoms & Phenotypes for Reflex Epilepsy

UMLS symptoms related to Reflex Epilepsy:


seizures

Drugs & Therapeutics for Reflex Epilepsy

Drugs for Reflex Epilepsy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Valproic Acid Approved, Investigational Phase 4 99-66-1 3121
2 Neurotransmitter Agents Phase 4,Phase 2
3 Anticonvulsants Phase 4,Phase 2
4 Antimanic Agents Phase 4,Phase 2
5 Central Nervous System Depressants Phase 4,Phase 2
6 GABA Agents Phase 4,Phase 2
7 Psychotropic Drugs Phase 4,Phase 2
8 Tranquilizing Agents Phase 4,Phase 2
9
Dopamine Approved Phase 2 51-61-6, 62-31-7 681
10
Ropinirole Approved, Investigational Phase 2 91374-20-8, 91374-21-9 5095 497540
11
Lorazepam Approved Phase 2 846-49-1 3958
12
Carbamazepine Approved, Investigational Phase 2 298-46-4 2554
13 Etiracetam Investigational Phase 2 33996-58-6
14 Antiparkinson Agents Phase 2
15 Dopamine Agents Phase 2
16 Dopamine agonists Phase 2
17 Anti-Anxiety Agents Phase 2
18 Antiemetics Phase 2
19 Autonomic Agents Phase 2
20 GABA Modulators Phase 2
21 Gastrointestinal Agents Phase 2
22 Hypnotics and Sedatives Phase 2
23 Peripheral Nervous System Agents Phase 2
24 Analgesics Phase 2
25 Analgesics, Non-Narcotic Phase 2
26 Cytochrome P-450 CYP3A Inducers Phase 2
27 Nootropic Agents Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Antispastic Effect of Transcranial Magnetic Stimulation in Patients With Cerebral and Spinal Spasticity Unknown status NCT01786005 Phase 4
2 Effect of Valproic Acid Concentration on Photic Response Completed NCT00609245 Phase 4 Valproic Acid;Placebo
3 Effect of Ropinirole Hydrochloride in Progressive Myoclonic Epilepsy of Unverricht-Lundborg Type Unknown status NCT00639119 Phase 2 Ropinirole
4 PF-06372865 in Subjects With Photosensitive Epilepsy Completed NCT02564029 Phase 2 PF-06372865;Placebo;Lorazepam
5 A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy Completed NCT00579384 Phase 2 JNJ-26489112;Placebo
6 Effect of BGG492 on EEG in Patients With Photosensitive Epilepsy Completed NCT00784212 Phase 2 BGG492;BGG492;Placebo
7 Photosensitivity Proof of Concept Trial Completed NCT00894010 Phase 2 carbamazepine 400mg;levetiracetam 1000mg
8 A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients Not yet recruiting NCT03239691 Phase 2 ACT-709478 for oral use;Placebo
9 Effect of Levetiracetam on Brain Excitability Completed NCT00006191
10 Neurophysiological Studies in Patients With Paroxysmal Hyperkinetic Movement Disorders Completed NCT00056888

Search NIH Clinical Center for Reflex Epilepsy

Cochrane evidence based reviews: epilepsy, reflex

Genetic Tests for Reflex Epilepsy

Anatomical Context for Reflex Epilepsy

MalaCards organs/tissues related to Reflex Epilepsy:

39
Brain, Thalamus, Temporal Lobe, Occipital Lobe

Publications for Reflex Epilepsy

Articles related to Reflex Epilepsy:

(show top 50) (show all 105)
id Title Authors Year
1
Seizures Induced by Exiting Water: A Unique Form of Reflex Epilepsy. ( 28859025 )
2017
2
Features of stimulus-specific seizures in dogs with reflex epilepsy: 43 cases (2000-2014). ( 28001116 )
2017
3
A Rare Reflex Epilepsy: Bathing-Related Epilepsy. ( 28680322 )
2017
4
Role of dietary and lifestyle modifications in reflex epilepsy based on traditional Persian medicine. ( 28088254 )
2017
5
Intractable ictal vomiting: a new form of reflex epilepsy? ( 28625944 )
2017
6
Rub Evoked Reflex Epilepsy in an Infant With Cerebellar Hypoplasia. ( 27268764 )
2016
7
A case of symptomatic reflex epilepsy precipitated by bathing. ( 27668179 )
2016
8
The Pivotal Role of the Parieto-Occipital Lobe in Card Game-Induced Reflex Epilepsy: A Voxel-Based Morphometry Study. ( 27344460 )
2016
9
Hot water epilepsy: A form of reflex epilepsy - from infancy to adolescence. ( 26752913 )
2015
10
Genetically epilepsy-prone rats (GEPRs) and DBA/2 mice: Two animal models of audiogenic reflex epilepsy for the evaluation of new generation AEDs. ( 26254980 )
2015
11
Autonomic function in reflex and non-reflex epilepsy - an exploratory study. ( 26369268 )
2015
12
Reflex Epilepsy Triggered by Smell. ( 25013184 )
2014
13
Blackouts in the toilet: a case of micturition-induced reflex epilepsy. ( 24567420 )
2014
14
Understanding the pathophysiology of reflex epilepsy using simultaneous EEG-fMRI. ( 24691294 )
2014
15
Hot water epilepsy: a video case of European boy with positive family history and subsequent non-reflex epilepsy. ( 24691301 )
2014
16
Micturition-induced seizures: a rare form of reflex epilepsy. ( 23827429 )
2013
17
Pure graphogenic epilepsy--a rare form of reflex epilepsy. ( 23786750 )
2013
18
Emotional stress-induced seizures: another reflex epilepsy? ( 22150553 )
2012
19
Reflex epilepsy induced by playing Go-stop or Baduk games. ( 22995679 )
2012
20
Opposite caudal versus rostral brain nitric oxide synthase response to generalized seizures in a novel rodent model of reflex epilepsy. ( 22326500 )
2012
21
Somatosensory rub evoked reflex epilepsy of a temporal lobe origin. ( 20640465 )
2011
22
Lesional reflex epilepsy associated with the thought of food. ( 20157165 )
2010
23
Hot water epilepsy: A rare form of reflex epilepsy. ( 21808513 )
2010
24
Lesional reflex epilepsy associated with the thought of food. ( 20644158 )
2010
25
Electroclinical characteristics of micturition-induced reflex epilepsy. ( 19204273 )
2009
26
A locus for autosomal dominant reflex epilepsy precipitated by hot water maps at chromosome 10q21.3-q22.3. ( 19266219 )
2009
27
Familial autosomal dominant reflex epilepsy triggered by hot water maps to 4q24-q28. ( 19597845 )
2009
28
Kinesigenic reflex epilepsy associated with a glioma in the lateral peri-rolandic region. ( 19286490 )
2009
29
Teaching Video NeuroImage: Electroclinical characteristics of micturition-induced reflex epilepsy. ( 18474839 )
2008
30
Micturition and emotion-induced reflex epilepsy: case report and review of the literature. ( 17201720 )
2006
31
Reflex seizures and reflex epilepsy. ( 16605171 )
2006
32
Reflex epilepsy induced by playing oriental card or board games. ( 20396530 )
2006
33
Transfer of an avian genetic reflex epilepsy by embryonic brain graft: a tissue autonomous process? ( 15906237 )
2005
34
Mah-Jong-induced epilepsy: a special reflex epilepsy in Chinese society. ( 15642495 )
2005
35
Telephone-induced seizures: a new type of reflex epilepsy. ( 15009231 )
2004
36
The reflex epilepsies with emphasis on photosensitive epilepsy. ( 16106643 )
2004
37
An avian model of genetic reflex epilepsy. ( 15260383 )
2004
38
Reflex epilepsy and non-ketotic hyperglycemia. ( 14684353 )
2003
39
Preventing seizures from "Pocket Monsters": a way to control reflex epilepsy. ( 11723255 )
2001
40
Rub epilepsy: a somatosensory evoked reflex epilepsy induced by prolonged cutaneous stimulation. ( 11254785 )
2001
41
Reflex epilepsy and reflex seizures of the visual system: a clinical review. ( 11022137 )
2000
42
Postoperative seizure outcome after corpus callosotomy in reflex epilepsy. ( 10746422 )
2000
43
Mah-jong epilepsy: a new reflex epilepsy. ( 10820911 )
2000
44
Seizures induced by frustration and despair due to unresolved moral and political issues: a rare case of reflex epilepsy. ( 10064177 )
1999
45
Photosensitive reflex epilepsy. ( 10999132 )
1999
46
Experimental models of reflex epilepsy. ( 9385411 )
1998
47
Seizure induction in reflex seizures and reflex epilepsy. ( 9385414 )
1998
48
Some considerations in the intensive electroencephalographic investigation of reflex epilepsy. ( 9385416 )
1998
49
Evoked responses and transcranial brain stimulation. Application to reflex epilepsy. ( 9385413 )
1998
50
The photosensitive epilepsy of the baboon. A model of generalized reflex epilepsy. ( 9385412 )
1998

Variations for Reflex Epilepsy

Expression for Reflex Epilepsy

Search GEO for disease gene expression data for Reflex Epilepsy.

Pathways for Reflex Epilepsy

GO Terms for Reflex Epilepsy

Sources for Reflex Epilepsy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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