MCID: RFL001
MIFTS: 51

Reflex Sympathetic Dystrophy

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Reflex Sympathetic Dystrophy

MalaCards integrated aliases for Reflex Sympathetic Dystrophy:

Name: Reflex Sympathetic Dystrophy 53 12 55 51 41 14 69
Reflex Sympathetic Dystrophy Syndrome 72 50
Algodystrophy 55 51
Complex Regional Pain Syndrome Type 1 55
Complex Regional Pain Syndromes 69
Complex Regional Pain Syndrome 55
Algodystrophic Syndrome 69

Characteristics:

Orphanet epidemiological data:

55
complex regional pain syndrome
Inheritance: Not applicable; Prevalence: 1-5/10000 (Netherlands); Age of onset: All ages; Age of death: normal life expectancy;
complex regional pain syndrome type 1
Age of onset: All ages;

Classifications:

Orphanet: 55  
Rare neurological diseases


External Ids:

OMIM 53 604335
Disease Ontology 12 DOID:1811
ICD10 32 G90.5 M89.0
MeSH 41 D012019
NCIt 46 C85042
MESH via Orphanet 42 D020918
UMLS via Orphanet 70 C0458219 C1527353 C0034931
ICD10 via Orphanet 33 G56.4 M89.0

Summaries for Reflex Sympathetic Dystrophy

NINDS : 50 Complex regional pain syndrome (CRPS) is a condition marked by severe, prolonged chronic pain (lasting more than six months) that may be constant. Symptoms vary in intensity and duration.  Some people describe it as a burning sensation, a "pins and needles" sensation, or as if an arm or leg is being squeezed.  The pain may spread to the entire arm or leg, even though the injury may have been only to a finger or toe.  Common symptoms include dramatic changes in the color and temperature of the skin over the affected limb or body part, accompanied by intense burning pain, increased sensitivity in the affected area, skin sensitivity, abnormal sweating, and abnormal movement in the affected limb.  In most instances the condition is triggered by a clear history of trauma or injury. CRPS also affects the immune system -- the disorder is more common in individuals with other inflammatory and autoimmune conditions such as asthma.  Limited data also suggests that CRPS may also be influenced by genetics.

MalaCards based summary : Reflex Sympathetic Dystrophy, also known as reflex sympathetic dystrophy syndrome, is related to complex regional pain syndrome and migraine with or without aura 1, and has symptoms including sleeplessness, vertigo/dizziness and chronic pain. An important gene associated with Reflex Sympathetic Dystrophy is CALCA (Calcitonin Related Polypeptide Alpha), and among its related pathways/superpathways are G alpha (s) signalling events and Adipocytokine signaling pathway. The drugs Bupivacaine and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and spinal cord.

Wikipedia : 72 Complex regional pain syndrome (CRPS), also known as reflex sympathetic dystrophy (RSD), is a disorder... more...

Description from OMIM: 604335

Related Diseases for Reflex Sympathetic Dystrophy

Diseases related to Reflex Sympathetic Dystrophy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 complex regional pain syndrome 33.2 CALCA NPY
2 migraine with or without aura 1 29.2 CALCA NPS
3 autonomic nervous system disease 28.9 CALCA CHSY1 NPS
4 algoneurodystrophy 11.8
5 causalgia 11.6
6 dysautonomia 11.4
7 neuropathy, hereditary sensory and autonomic, type iii 11.1
8 autonomic dysfunction 11.1
9 episodic pain syndrome, familial, 1 10.8
10 paine syndrome 10.7
11 burns 10.2
12 hemiplegia 10.2
13 dystonia 10.2
14 neuropathy 10.2
15 hydrops, lactic acidosis, and sideroblastic anemia 10.2
16 chronic pain 10.2
17 brittle bone disorder 10.1
18 arthritis 10.1
19 conversion disorder 10.1
20 leprosy 2 10.1 CALCA NPY
21 epispadias 10.1 CALCA NPY
22 carcinoid syndrome 10.1 CALCA NPY
23 degenerative disc disease 10.0 CALCA NPY
24 erythermalgia, primary 10.0
25 systemic lupus erythematosus 10.0
26 psoriatic arthritis 10.0
27 osteomalacia 10.0
28 myofascial pain syndrome 10.0
29 pancoast tumor 10.0
30 lupus erythematosus 10.0
31 erythromelalgia 10.0
32 primary hyperparathyroidism 10.0 CALCA CD36
33 amyotrophic lateral sclerosis 1 9.8
34 blood group, i system 9.8
35 cryoglobulinemia, familial mixed 9.8
36 renal cell carcinoma, nonpapillary 9.8
37 hyperreflexia 9.8
38 nail disorder, nonsyndromic congenital, 3 9.8
39 thrombophilia due to thrombin defect 9.8
40 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 9.8
41 eosinophilic fasciitis 9.8
42 familial mediterranean fever 9.8
43 metabolic encephalomyopathic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 9.8
44 arteriovenous fistula 9.8
45 chronic venous leg ulcers 9.8
46 hepatitis 9.8
47 spinal cord injury 9.8
48 thrombosis 9.8
49 fanconi syndrome 9.8
50 brucellosis 9.8

Graphical network of the top 20 diseases related to Reflex Sympathetic Dystrophy:



Diseases related to Reflex Sympathetic Dystrophy

Symptoms & Phenotypes for Reflex Sympathetic Dystrophy

Clinical features from OMIM:

604335

UMLS symptoms related to Reflex Sympathetic Dystrophy:


sleeplessness, vertigo/dizziness, chronic pain, tremor, syncope, seizures, sciatica, pain, neuralgia, headache, back pain

Drugs & Therapeutics for Reflex Sympathetic Dystrophy

Drugs for Reflex Sympathetic Dystrophy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 140)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bupivacaine Approved, Investigational Phase 4,Phase 3 38396-39-3, 2180-92-9 2474
2
Triamcinolone Approved, Vet_approved Phase 4,Phase 3 124-94-7 31307
3
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
4
gamma-Aminobutyric acid Approved, Investigational Phase 4 56-12-2 119
5
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
6
Salmon Calcitonin Approved, Investigational Phase 4 47931-85-1 16129616
7
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 437-38-7 3345
8
Acetaminophen Approved Phase 4 103-90-2 1983
9
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
10
Vitamin C Approved, Nutraceutical Phase 4,Phase 3 50-81-7 54670067 5785
11 Antioxidants Phase 4,Phase 3
12 Micronutrients Phase 4,Phase 3
13 Protective Agents Phase 4,Phase 3
14 Trace Elements Phase 4,Phase 3
15 Vitamins Phase 4,Phase 3
16 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
17 Anesthetics Phase 4,Phase 3,Phase 2
18 Anesthetics, Local Phase 4,Phase 3,Phase 2
19 Central Nervous System Depressants Phase 4,Phase 3,Phase 2
20 Neurotransmitter Agents Phase 4,Phase 2
21 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
22 Psychotropic Drugs Phase 4,Phase 2
23 Bone Density Conservation Agents Phase 4,Phase 2,Phase 3
24 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
25 triamcinolone acetonide Phase 4,Phase 3
26 Triamcinolone diacetate Phase 4,Phase 3
27 Triamcinolone hexacetonide Phase 4,Phase 3
28 Anti-Anxiety Agents Phase 4,Phase 2
29 Anti-Arrhythmia Agents Phase 4,Phase 2
30 Anticonvulsants Phase 4,Phase 2
31 Antimanic Agents Phase 4
32 Antiparkinson Agents Phase 4
33 calcium channel blockers Phase 4,Phase 2
34 Calcium, Dietary Phase 4,Phase 3,Phase 2
35 Diuretics, Potassium Sparing Phase 4
36 Excitatory Amino Acid Antagonists Phase 4,Phase 2
37 Excitatory Amino Acids Phase 4,Phase 2
38 GABA Agents Phase 4
39 Sodium Channel Blockers Phase 4
40 Tranquilizing Agents Phase 4,Phase 2
41 calcitonin Phase 4
42 Calcitonin Gene-Related Peptide Phase 4
43 Vasodilator Agents Phase 4,Phase 2
44 Adjuvants, Anesthesia Phase 4,Phase 3
45 Analgesics, Opioid Phase 4,Phase 3
46 Anesthetics, General Phase 4,Phase 3,Phase 2
47 Anesthetics, Intravenous Phase 4,Phase 3,Phase 2
48 Narcotics Phase 4,Phase 3
49 Antipyretics Phase 4
50
Ropivacaine Approved Phase 3 84057-95-4 175805 71273

Interventional clinical trials:

(show top 50) (show all 123)

# Name Status NCT ID Phase Drugs
1 Prophylactic Administration of Vitamin C in Wrist Fractures Completed NCT00296868 Phase 4 ascorbic acid (vitamin C) versus placebo
2 Restore Claims Characterization Study Completed NCT00200122 Phase 4
3 A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions Completed NCT00904202 Phase 4 Placebo Capsules + Placebo Patch;Placebo capsules + Lidoderm®;Gabapentin + Placebo;Gabapentin + Lidoderm®;Gabapentin 300 mg capsules 1800 mg/day + placebo patch;Gabapentin 1800 mg/day + Lidoderm patch
4 High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System Completed NCT02265848 Phase 4
5 Bupivacaine Versus Lidocaine Local Anesthesia Completed NCT01751347 Phase 4 Bupivacaine;Lidocaine
6 Efficacy and Safety of Salmon Calcitonin Nasal Spray in Improving Muscle Strength and Reducing Pain After Forearm Fracture in Postmenopausal Women Completed NCT00239889 Phase 4 Salmon calcitonin
7 Study on Impact of Fentanyl Matrix on Improvement of Pain and Functioning in Spinal Disorder-related Pain Completed NCT00797017 Phase 4 fentanyl;fentanyl;fentanyl;fentanyl;fentanyl;fentanyl;fentanyl
8 A Study on Health - Related Quality of Life in Patients With Rheumatic Diseases Taking Tramadol 37.5mg/Acetaminophen 325mg Tablets Completed NCT00642837 Phase 4 Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen
9 Tolerability of Suprascapular and Median Nerve Blocks for the Treatment of Shoulder-hand Syndrome Not yet recruiting NCT03291197 Phase 4 Suprascapular and median nerve blocks
10 Acupuncture for Post-stroke Shoulder-hand Syndrome Unknown status NCT02011854 Phase 2, Phase 3
11 RCT :Thoracic Sympathetic Block for the Treatment of Complex Regional Pain Syndrome I of the Upper Limb Unknown status NCT01612364 Phase 3
12 Intravenous Immunoglobulins in Complex-regional Pain Syndrome Unknown status NCT00949065 Phase 3
13 Surgical Treatment Of Complex Regional Pain Syndrome Type II (CRPS II) Unknown status NCT01392599 Phase 3
14 Analysis of Photoplethysmographic Signal in Lumbar Sympathetic Block Unknown status NCT01134289 Phase 3
15 Efficacy and Safety of Intravenous Neridronic Acid in CRPS-I Completed NCT02402530 Phase 2, Phase 3 Placebo;Neridronic acid 62.5 mg
16 Pain Exposure Physical Therapy (PEPT) Versus CBO in Patients With Complex Regional Pain Syndrome Type I (CRPS-1) Completed NCT00817128 Phase 2, Phase 3
17 A Study of the Effect of Lenalidamide on Complex Regional Pain Syndrome Type 1 Completed NCT00166452 Phase 3 Lenalidamide
18 A Confirmatory Study of Fentanyl in Participants With Post-herpetic Neuralgia, Complex Regional Pain Syndrome or Postoperative Pain Syndrome Completed NCT01008553 Phase 3 Fentanyl;Placebo
19 STRIPS: Shoulder Taping Reduces Injury and Pain in Stroke Completed NCT01062308 Phase 3
20 Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time Completed NCT01223365 Phase 3 Hydrocodone ER
21 Study to Evaluate the Efficacy and Safety of OraVescent Fentanyl Citrate Treatment for the Management of Breakthrough Pain in Opioid-Tolerant Patients With Noncancer-Related Chronic Pain Completed NCT00343733 Phase 3 OraVescent Fentanyl
22 Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery Recruiting NCT02390505 Phase 3 Vitamin C;Placebo
23 Safety of Intravenous Neridronic Acid in CRPS Active, not recruiting NCT02972359 Phase 3 Neridronic acid
24 CREATE-1: A Study to Assess the Efficacy and Safety of AXS-02 in Patients With CRPS-1 Terminated NCT02504008 Phase 3 AXS-02 (oral zoledronate);Placebo
25 Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception Withdrawn NCT00349050 Phase 2, Phase 3
26 The Use of Zoledronic Acid to Complex Regional Pain Syndrome Unknown status NCT01788176 Phase 2 Zoledronic acid;Placebo
27 Effect of Delta-9-Tetrahydrocannabinol on the Prevention of Chronic Pain in Patients With Acute CRPS (ETIC-Study) Unknown status NCT00377468 Phase 2 Delta9-Tetrahydrocannabinol
28 Dupuytren's Disease and Extracorporeal Shockwave Therapy (DupuyShock-2010) Unknown status NCT01184586 Phase 2
29 A Study of CC-5013 in the Treatment of Complex Regional Pain Syndrome (CRPS) Completed NCT00067743 Phase 2 Lenalidomide
30 Double Blind Placebo Controlled Study of Outpatient Intravenous Ketamine for the Treatment of CRPS Completed NCT00579085 Phase 2 Ketamine
31 Prospective, Randomized Controlled Trial on Perioperative Pregabalin to Reduce Late-onset CRPS After TKA Completed NCT00558753 Phase 2 pregabalin;Placebo
32 Novel Treatment Option for Neuropathic Pain Completed NCT02490436 Phase 2 Cetuximab;Placebo
33 Amitriptyline Regarding Nimesulide in Acute Idiopathic Adhesive Capsulitis Completed NCT01306708 Phase 2 amitriptyline
34 A Pilot Trial of IV Pamidronate for Low Back Pain Completed NCT01210599 Phase 1, Phase 2 Pamidronate
35 Effects of Vaporized Marijuana on Neuropathic Pain Completed NCT01037088 Phase 1, Phase 2 Mild dose cannabis;Low dose cannabis;Cannabis
36 Study of HC-58 in Upper Limb Hemiplegic Patients After Stroke Completed NCT01623622 Phase 2 HC-58;Placebo
37 Clonidine Versus Adenosine to Treat Neuropathic Pain Completed NCT00349921 Phase 2 clonidine;adenosine;placebo;placebo
38 Adipose Stem/Stromal Cells in RSD, CRPS, Fibromyalgia Recruiting NCT02987855 Phase 1, Phase 2
39 Study to Evaluate the Efficacy and Safety of Lenalidomide in the Treatment of Complex Regional Pain Syndrome Type 1 Terminated NCT00109772 Phase 2 lenalidomide;Placebo
40 Randomized Controlled Trial of Ketamine Infusion With Continuous Epidural Infusion for Treatment of Complex Regional Pain Syndrome Terminated NCT02094352 Phase 2 Ketamine Infusion + Epidural Infusion;Control Group + Epidural infusion;Ketamine Booster Infusion;Control Group Booster Infusion
41 Safety and Efficacy Study of Ethosuximide for the Treatment of Complex Regional Pain Syndrome (CRPS) Terminated NCT00689585 Phase 2 Placebo;Ethosuximide
42 Neurotropin to Treat Chronic Neuropathic Pain Terminated NCT00006289 Phase 2 Placebo;Neurotropin
43 Efficacy of Etoricoxib on Peripheral Hyperalgesia Terminated NCT01088256 Phase 2 Etoricoxib;placebo
44 Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain. Suspended NCT02321566 Phase 1
45 Two Measures of Tactile Acuity in CRPS Type I Patients Unknown status NCT01888783
46 Effects of Repetitive Electric Sensory Stimulation (RSS) as Intervention in Complex-regional-pain-syndrome Type I (CRPS) Unknown status NCT01915329
47 Neurophysiological Basis of Rehabilitation in Complex Regional Pain Syndrome, Type I and Chronic Low Back Pain Unknown status NCT02347579
48 The Effect of Vitamin c on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture Unknown status NCT01338129 placebo
49 Use of Compression Glove to Prevent Complications After Distal Radius Fractures: a Randomized Controlled Trial Unknown status NCT01118715
50 Structural and Functional Nerve Changes Following Immobilisation After Distal Radius Fracture - a Pilot Study (NRP) Unknown status NCT02396277

Search NIH Clinical Center for Reflex Sympathetic Dystrophy

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: reflex sympathetic dystrophy

Genetic Tests for Reflex Sympathetic Dystrophy

Anatomical Context for Reflex Sympathetic Dystrophy

MalaCards organs/tissues related to Reflex Sympathetic Dystrophy:

38
Skin, Bone, Spinal Cord, Cortex, Dorsal Root Ganglion, Heart, Testes

Publications for Reflex Sympathetic Dystrophy

Articles related to Reflex Sympathetic Dystrophy:

(show top 50) (show all 512)
# Title Authors Year
1
Bone SPECT/CT Localizes Increased Bone Metabolism and Subsequent Bone Resorption in Reflex Sympathetic Dystrophy. ( 28806248 )
2017
2
How a Simple Ankle Sprain Turned Into Neuropathic Pain: Complex Reflex Sympathetic Dystrophy Versus Erythromelalgia. ( 29121832 )
2017
3
Pain, Complex Regional Pain Syndrome (Reflex Sympathetic Dystrophy, RSD, CRPS) ( 28613470 )
2017
4
The Relation Between Reflex Sympathetic Dystrophy Syndrome and Trauma Severity in Patients With Distal Tibia Fracture. ( 27626009 )
2016
5
Re: del Pinal F. Editorial: I have a dream ... reflex sympathetic dystrophy (RSD or Complex Regional Pain Syndrome - CRPS I) does not exist. J Hand Surg Eur. 2013, 38: 595-7. ( 24448795 )
2014
6
Sympathomimetic amine therapy found effective for treatment of refractory chronic complex regional pain syndrome (reflex sympathetic dystrophy). ( 25134306 )
2014
7
Reflex sympathetic dystrophy-like syndrome, possibly caused by aripiprazole, in an adolescent patient. ( 25020186 )
2014
8
Re: del Pinal F. Editorial: I have a dream ... reflex sympathetic dystrophy (RSD or Complex Regional Pain Syndrome - CRPS I) does not exist. J Hand Surg Eur. 2013, 38: 595-7. ( 24566455 )
2014
9
Re: del PiA+al F. Editorial: I have a dream ... reflex sympathetic dystrophy (RSD or Complex Regional Pain Syndrome--CRPS 1) does not exist. J Hand Surg Eur. 2013, 38: 595-7. ( 24158709 )
2013
10
Editorial. I have a dream ... reflex sympathetic dystrophy (RSD or Complex Regional Pain Syndrome - CRPS I) does not exist. ( 23778064 )
2013
11
A case of linear morphoea mistaken for reflex sympathetic dystrophy. ( 23546034 )
2013
12
Unilateral Beau's lines in a case of complex regional pain syndrome (reflex sympathetic dystrophy). ( 23075662 )
2012
13
Lawsuit verdicts and settlements involving reflex sympathetic dystrophy and complex regional pain syndrome. ( 22214139 )
2011
14
Reflex sympathetic dystrophy following pacemaker insertion. ( 22334977 )
2011
15
Induction of prolonged mania during ketamine therapy for reflex sympathetic dystrophy. ( 21529780 )
2011
16
My sister fell and injured her shoulder a few months ago. She's developed terrible burning pain down into her arm. Her doctor says she has complex regional pain syndrome, also known as reflex sympathetic dystrophy. What is it? How is it treated? ( 21344692 )
2011
17
Is this complex regional pain syndrome or reflex sympathetic dystrophy? ( 21632229 )
2011
18
Reflex sympathetic dystrophy syndrome in a child. ( 21993705 )
2011
19
Tenosynovitis caused by a pseudallescheria boydii infection and symptoms of reflex sympathetic dystrophy after a dog bite. ( 21946460 )
2011
20
Reflex sympathetic dystrophy in patients with metastatic renal cell carcinoma treated with everolimus. ( 19649567 )
2010
21
A severe case of complex regional pain syndrome I (reflex sympathetic dystrophy) managed with spinal cord stimulation. ( 19863748 )
2010
22
Reply: Is reflex sympathetic dystrophy/complex regional pain syndrome type I a small-fiber neuropathy? ( 20583223 )
2010
23
Complex regional pain syndrome/reflex sympathetic dystrophy. ( 20504141 )
2010
24
A hypothesis for the cause of complex regional pain syndrome-type I (reflex sympathetic dystrophy): pain due to deep-tissue microvascular pathology. ( 20704671 )
2010
25
Is reflex sympathetic dystrophy/complex regional pain syndrome type I a small-fiber neuropathy? ( 19557864 )
2009
26
The efficacy of manual lymphatic drainage therapy in the management of limb edema secondary to reflex sympathetic dystrophy. ( 19030864 )
2009
27
Reflex sympathetic dystrophy secondary to deep venous thrombosis mimicking post-thrombotic syndrome. ( 19363611 )
2009
28
Reflex sympathetic dystrophy/complex regional pain syndrome. ( 18306652 )
2008
29
Unilateral trachyonychia in a patient with reflex sympathetic dystrophy. ( 18222330 )
2008
30
Reflex sympathetic dystrophy: complex regional pain syndrome type I in children with mitochondrial disease and maternal inheritance. ( 18192313 )
2008
31
Factitious lymphoedema as a psychiatric condition mimicking reflex sympathetic dystrophy: a case report. ( 18577230 )
2008
32
Effects of weather changes on a patient with reflex sympathetic dystrophy. ( 17387368 )
2007
33
Complex regional pain syndrome (reflex sympathetic dystrophy) in a patient with essential mixed cryoglobulinemia and chronic hepatitis C. ( 17370795 )
2007
34
Reflex sympathetic dystrophy in a renal transplant patient treated with sirolimus. ( 17575313 )
2007
35
Reflex sympathetic dystrophy: a retrospective epidemiological study of 168 patients. ( 17221145 )
2007
36
The effect of gabapentin in earlier stage of reflex sympathetic dystrophy. ( 16897121 )
2007
37
Reflex sympathetic dystrophy: reflections from a clinician. ( 18605399 )
2007
38
Complex regional pain syndrome I (reflex sympathetic dystrophy) associated with a superficial hand burn from a fan heater. ( 17535413 )
2007
39
Unusual cases of acquired leukonychia totalis and partialis secondary to reflex sympathetic dystrophy. ( 17958875 )
2007
40
Reflex sympathetic dystrophy: a case of total body pain. ( 17721352 )
2007
41
Impact of three-phase bone scintigraphy on the diagnosis and treatment of complex regional pain syndrome type I or reflex sympathetic dystrophy. ( 16340227 )
2006
42
The role of the pain psychologist, trigger point injections, reflex sympathetic dystrophy. ( 17182517 )
2006
43
Current management of reflex sympathetic dystrophy syndrome (complex regional pain syndrome type I). ( 16837228 )
2006
44
Spinal cord stimulation for chronic reflex sympathetic dystrophy--five-year follow-up. ( 16738284 )
2006
45
Evidence of focal small-fiber axonal degeneration in complex regional pain syndrome-I (reflex sympathetic dystrophy). ( 16427737 )
2006
46
Determination of inflammation of reflex sympathetic dystrophy at early stages with Tc-99m HIG scintigraphy: preliminary results. ( 16025330 )
2006
47
Psychiatric approach in the treatment of reflex sympathetic dystrophy in an adolescent girl: a case report. ( 17290576 )
2006
48
Reflex sympathetic dystrophy in hemiplegia. ( 17106342 )
2006
49
The challenge to manage reflex sympathetic dystrophy/complex regional pain syndrome. ( 16139630 )
2005
50
Treatment of reflex sympathetic dystrophy in children using a prostacyclin analog: preliminary results. ( 15805955 )
2005

Variations for Reflex Sympathetic Dystrophy

Expression for Reflex Sympathetic Dystrophy

Search GEO for disease gene expression data for Reflex Sympathetic Dystrophy.

Pathways for Reflex Sympathetic Dystrophy

Pathways related to Reflex Sympathetic Dystrophy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.32 CALCA NPS
2 10.79 CD36 NPY
3 10.15 CALCA NPY

GO Terms for Reflex Sympathetic Dystrophy

Biological processes related to Reflex Sympathetic Dystrophy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cytosolic calcium ion concentration GO:0007204 9.37 CALCA CD36
2 regulation of blood pressure GO:0008217 9.32 CALCA NPY
3 feeding behavior GO:0007631 9.26 CALCA NPY
4 receptor internalization GO:0031623 9.16 CALCA CD36
5 negative regulation of ossification GO:0030279 8.96 CALCA CHSY1
6 neuropeptide signaling pathway GO:0007218 8.8 CALCA NPS NPY

Molecular functions related to Reflex Sympathetic Dystrophy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 CALCA NPY

Sources for Reflex Sympathetic Dystrophy

3 CDC
7 CNVD
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10 dbSNP
11 DGIdb
16 ExPASy
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27 GO
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29 HGMD
30 HMDB
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32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
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36 KEGG
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65 SNOMED-CT via HPO
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