MCID: RGL001
MIFTS: 21

Regular Astigmatism malady

Category: Eye diseases

Aliases & Classifications for Regular Astigmatism

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Aliases & Descriptions for Regular Astigmatism:

Name: Regular Astigmatism 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:11781
ICD1027 H52.22
SNOMED-CT59 68905002
ICD9CM29 367.21
UMLS65 C0152193

Summaries for Regular Astigmatism

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MalaCards based summary: Regular Astigmatism is related to colorectal cancer and waardenburg syndrome, type 1. An important gene associated with Regular Astigmatism is CER1 (Cerberus 1, DAN Family BMP Antagonist), and among its related pathways are HTLV-I infection and . Affiliated tissues include eye, and related mouse phenotype hematopoietic system.

Related Diseases for Regular Astigmatism

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Diseases related to Regular Astigmatism via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1colorectal cancer10.1
2waardenburg syndrome, type 110.1
3glossitis10.1
4precocious puberty10.1
5anthracosilicosis10.1HLA-G, MS4A2
6disuse amblyopia9.9CYLC1, DPT
7degeneration of macula and posterior pole9.7DPT, LCK, MATK
8amblyopia9.6DPT, NBL1
9astigmatism7.1ASPH, CDKN2A, CER1, CYLC1, CYLD, DPT

Graphical network of diseases related to Regular Astigmatism:



Diseases related to regular astigmatism

Symptoms for Regular Astigmatism

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Drugs & Therapeutics for Regular Astigmatism

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Interventional clinical trials:

idNameStatusNCT IDPhase
1SUPRACOR for Myopia and Myopic AstigmatismActive, not recruitingNCT01404884Phase 3
2Study of Clinical Performance of Corneal Topography Measurement Using an Optical BiometerCompletedNCT01861925
3Fourier Transform of Videokeratography Data: Clinical Usefulness in Moderate and Frome Fruste KeratoconusCompletedNCT02617368
4ACRYSOF® Toric NATURAL T9 Intraocular Lens (IOL)CompletedNCT00967473
5Observational Study of Keratoconus and Post-keratoplasty EyesRecruitingNCT02109848
6Limbal Relaxing Incision Versus Toric Intraocular Lens for Corneal Astigmatism During Cataract Surgery.RecruitingNCT02067429
7Measurement Repeatability in Contemporary AberrometryNot yet recruitingNCT02687022
8A Trial of Toric Versus Non-toric Intraocular Lenses in Phacoemulsification Cataract SurgeryNot yet recruitingNCT01712503

Search NIH Clinical Center for Regular Astigmatism

Genetic Tests for Regular Astigmatism

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Anatomical Context for Regular Astigmatism

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MalaCards organs/tissues related to Regular Astigmatism:

33
Eye

Animal Models for Regular Astigmatism or affiliated genes

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MGI Mouse Phenotypes related to Regular Astigmatism:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.6CDKN2A, CYLD, HLA-G, LCK, MATK, MS4A2

Publications for Regular Astigmatism

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Articles related to Regular Astigmatism:

idTitleAuthorsYear
1
Frontotemporal degeneration in the patient with amyotrophic lateral sclerosis: helping the caregiver cope. (23422695)
2013
2
Quantitative profiling of gut microbiota of children with diarrhea-predominant irritable bowel syndrome. (22986438)
2012
3
Dynamin inhibition blocks botulinum neurotoxin type A endocytosis in neurons and delays botulism. (21832053)
2011
4
Kinetics of plasma SPB and RAGE during mechanical ventilation in patients undergoing major vascular surgery. (21736957)
2011
5
Metopic and sagittal synostosis: intracranial volume measurements prior to and after cranio-orbital reshaping in childhood. (7624402)
1995

Variations for Regular Astigmatism

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Expression for genes affiliated with Regular Astigmatism

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Search GEO for disease gene expression data for Regular Astigmatism.

Pathways for genes affiliated with Regular Astigmatism

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Pathways related to Regular Astigmatism according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5CDKN2A, HLA-G, LCK
2
Show member pathways
9.1CDKN2A, HLA-G, LCK

GO Terms for genes affiliated with Regular Astigmatism

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Biological processes related to Regular Astigmatism according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of NF-kappaB transcription factor activityGO:00320889.8CDKN2A, CYLD
2sequestering of BMP in extracellular matrixGO:00355829.8CER1, NBL1
3determination of dorsal identityGO:00482639.8CER1, NBL1
4peptidyl-tyrosine autophosphorylationGO:00380839.6LCK, MATK

Sources for Regular Astigmatism

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet