MCID: RGL001
MIFTS: 23

Regular Astigmatism malady

Category: Eye diseases

Aliases & Classifications for Regular Astigmatism

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Aliases & Descriptions for Regular Astigmatism:

Name: Regular Astigmatism 10 12 65

Classifications:



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Disease Ontology10 DOID:11781
ICD1027 H52.22
SNOMED-CT59 68905002
ICD9CM29 367.21
UMLS65 C0152193

Summaries for Regular Astigmatism

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MalaCards based summary: Regular Astigmatism is related to astigmatism and anthracosilicosis. An important gene associated with Regular Astigmatism is CER1 (Cerberus 1, DAN Family BMP Antagonist), and among its related pathways are HTLV-I infection and TGF-beta Signaling Pathway (sino). Affiliated tissues include eye and endothelial, and related mouse phenotype hematopoietic system.

Related Diseases for Regular Astigmatism

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Diseases related to Regular Astigmatism via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1astigmatism23.8ASPH, CDKN2A, CER1, CYLC1, CYLD, DPT
2anthracosilicosis10.1HLA-G, MS4A2
3cataract9.9
4keratoconus9.9
5refractive error9.9
6endotheliitis9.9
7disuse amblyopia9.8CYLC1, DPT
8degeneration of macula and posterior pole9.5DPT, LCK, MATK
9amblyopia9.4DPT, NBL1

Graphical network of diseases related to Regular Astigmatism:



Diseases related to regular astigmatism

Symptoms for Regular Astigmatism

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Drugs & Therapeutics for Regular Astigmatism

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Interventional clinical trials:

idNameStatusNCT IDPhase
1SUPRACOR for Myopia and Myopic AstigmatismActive, not recruitingNCT01404884Phase 3
2Study of Clinical Performance of Corneal Topography Measurement Using an Optical BiometerCompletedNCT01861925
3Fourier Transform of Videokeratography Data: Clinical Usefulness in Moderate and Frome Fruste KeratoconusCompletedNCT02617368
4ACRYSOF® Toric NATURAL T9 Intraocular Lens (IOL)CompletedNCT00967473
5Observational Study of Keratoconus and Post-keratoplasty EyesRecruitingNCT02109848
6Limbal Relaxing Incision Versus Toric Intraocular Lens for Corneal Astigmatism During Cataract Surgery.RecruitingNCT02067429
7Measurement Repeatability in Contemporary AberrometryNot yet recruitingNCT02687022
8A Trial of Toric Versus Non-toric Intraocular Lenses in Phacoemulsification Cataract SurgeryNot yet recruitingNCT01712503

Search NIH Clinical Center for Regular Astigmatism

Genetic Tests for Regular Astigmatism

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Anatomical Context for Regular Astigmatism

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MalaCards organs/tissues related to Regular Astigmatism:

33
Eye, Endothelial

Animal Models for Regular Astigmatism or affiliated genes

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MGI Mouse Phenotypes related to Regular Astigmatism:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.6CDKN2A, CYLD, HLA-G, LCK, MATK, MS4A2

Publications for Regular Astigmatism

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Articles related to Regular Astigmatism:

idTitleAuthorsYear
1
Evaluation of the orientation of the steepest meridian of regular astigmatism among highly myopic Egyptian patients seeking non-ablative surgical correction of the refractive error. (26435831)
2015
2
Comparison of two different scheimpflug devices in the detection of keratoconus, regular astigmatism, and healthy corneas. (25954510)
2015
3
Combined special capsular tension ring and toric IOL implantation for management of post-DALK high regular astigmatism with subluxated traumatic cataract. (25116780)
2014
4
Combined Descemet-stripping automated endothelial keratoplasty and phacoemulsification with toric intraocular lens implantation for treatment of failed penetrating keratoplasty with high regular astigmatism. (22296843)
2012
5
Bivariate analysis of surgically induced regular astigmatism. Mathematical analysis and graphical display. (10615439)
1999

Variations for Regular Astigmatism

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Expression for genes affiliated with Regular Astigmatism

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Search GEO for disease gene expression data for Regular Astigmatism.

Pathways for genes affiliated with Regular Astigmatism

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Pathways related to Regular Astigmatism according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5CDKN2A, HLA-G, LCK
2
Show member pathways
9.1CER1, DPT, NBL1

GO Terms for genes affiliated with Regular Astigmatism

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Biological processes related to Regular Astigmatism according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of NF-kappaB transcription factor activityGO:00320889.8CDKN2A, CYLD
2sequestering of BMP in extracellular matrixGO:00355829.8CER1, NBL1
3determination of dorsal identityGO:00482639.8CER1, NBL1
4peptidyl-tyrosine autophosphorylationGO:00380839.6LCK, MATK

Sources for Regular Astigmatism

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet