MCID: RNR002
MIFTS: 8

Ren-Related Kidney Disease

Categories: Genetic diseases, Nephrological diseases

Aliases & Classifications for Ren-Related Kidney Disease

MalaCards integrated aliases for Ren-Related Kidney Disease:

Name: Ren-Related Kidney Disease 24
Hyperuricemic Nephropathy, Familial Juvenile 2 69
Familial Juvenile Hyperuricemic Nephropathy 2 24

Classifications:



External Ids:

UMLS 69 C2751310

Summaries for Ren-Related Kidney Disease

Genetics Home Reference : 24 REN-related kidney disease is an inherited condition that affects kidney function. This condition causes slowly progressive kidney disease that usually becomes apparent during childhood. As this condition progresses, the kidneys become less able to filter fluids and waste products from the body, resulting in kidney failure. Individuals with REN-related kidney disease typically require dialysis (to remove wastes from the blood) or a kidney transplant between ages 40 and 70.

MalaCards based summary : Ren-Related Kidney Disease, also known as hyperuricemic nephropathy, familial juvenile 2, is related to hyperuricemic nephropathy, familial juvenile, 2. An important gene associated with Ren-Related Kidney Disease is REN (Renin). Affiliated tissues include kidney.

Related Diseases for Ren-Related Kidney Disease

Diseases related to Ren-Related Kidney Disease via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hyperuricemic nephropathy, familial juvenile, 2 11.9

Symptoms & Phenotypes for Ren-Related Kidney Disease

Drugs & Therapeutics for Ren-Related Kidney Disease

Search Clinical Trials , NIH Clinical Center for Ren-Related Kidney Disease

Genetic Tests for Ren-Related Kidney Disease

Anatomical Context for Ren-Related Kidney Disease

MalaCards organs/tissues related to Ren-Related Kidney Disease:

38
Kidney

Publications for Ren-Related Kidney Disease

Variations for Ren-Related Kidney Disease

ClinVar genetic disease variations for Ren-Related Kidney Disease:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 REN REN, 3-BP DEL, 45GCT deletion Pathogenic
2 REN NM_000537.3(REN): c.47T> G (p.Leu16Arg) single nucleotide variant Pathogenic rs121917743 GRCh37 Chromosome 1, 204135375: 204135375

Expression for Ren-Related Kidney Disease

Search GEO for disease gene expression data for Ren-Related Kidney Disease.

Pathways for Ren-Related Kidney Disease

GO Terms for Ren-Related Kidney Disease

Sources for Ren-Related Kidney Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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