Renal Cell Carcinoma malady

Genetic diseases, Nephrological diseases, Cancer diseases, Rare diseases categories

Summaries for Renal Cell Carcinoma

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OMIM:47 The Heidelberg histologic classification of renal cell tumors subdivides renal cell tumors into benign and malignant... (144700) more...

MalaCards based summary: Renal Cell Carcinoma, also known as renal carcinoma, chromophobe, somatic, is related to renal oncocytoma and kidney cancer, and has symptoms including sporadicand renal cell carcinoma. An important gene associated with Renal Cell Carcinoma is VHL (von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase), and among its related pathways are Regulation of beta-cell development and Renal cell carcinoma. The drugs medroxyprogesterone and medroxyprogesterone acetate and the compounds nnmt and glucose have been mentioned in the context of this disorder. Affiliated tissues include kidney, endothelial and t cells, and related mouse phenotypes are liver/biliary system and renal/urinary system.

Disease Ontology:10 A renal carcinoma that has material basis in the lining of the proximal convoluted renal tubule of the kidney.

Novus Biologicals:46 Renal cell carcinoma originates in the proximal renal tube and is the most common form of kidney cancer. Renal cell carcinoma is resistant to radiation therapy and chemotherapy, however some cases respond to immunotherapy. Interleukin-2 has produced remission in some patients, as has functional restoration of the VHL gene.

Wikipedia:65 Renal cell carcinoma (RCC, also known as hypernephroma, Grawitz tumor, renal adenocarcinoma) is a kidney... more...

Aliases & Classifications for Renal Cell Carcinoma

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47OMIM, 32LifeMap Discovery®, 10Disease Ontology, 12DISEASES, 49Orphanet, 62UMLS, 11diseasecard, 24GTR, 35MeSH, 57SNOMED-CT, 40NCIt, 28ICD10 via Orphanet, 63UMLS via Orphanet, 36MESH via Orphanet
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Renal Cell Carcinoma, Aliases & Descriptions:

Name: Renal Cell Carcinoma 47 32 10 12 49 62
Renal Carcinoma, Chromophobe, Somatic 47 11
Nonpapillary Renal Cell Carcinoma 10 24
Adenocarcinoma of Kidney 10 62
Rcc 10 49
Renal Cell Carcinoma, Clear Cell, Somatic 47
Conventional Renal Cell Carcinoma 62
Renal Cell Carcinoma, Somatic 47
Hypernephroma 10


Characteristics (Orphanet epidemiological data):

renal cell carcinoma:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: Adult

External Ids:

OMIM47 144700
Disease Ontology10 DOID:0050387, DOID:4450
MeSH35 D002292
NCIt40 C9385
SNOMED-CT57 41607009, 254915003
Orphanet49 217071
ICD10 via Orphanet28 C64
UMLS via Orphanet63 C0007134
MESH via Orphanet36 D002292

Related Diseases for Renal Cell Carcinoma

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Diseases in the Renal Cell Carcinoma family:

Renal Clear Cell Carcinoma Hereditary Renal Cell Carcinoma
Familial Renal Cell Carcinoma Renal Cell Carcinoma 4

Diseases related to Renal Cell Carcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 369)
idRelated DiseaseScoreTop Affiliating Genes
1renal oncocytoma31.5FLCN, PRCC
2kidney cancer31.1FLCN, MET, VHL, CA9
3adenoma31.1MET, VHL, HNF1A, OGG1
4cystic kidney31.0VHL, HNF1B
5sarcoma31.0CA9, MET, TFE3
6adenocarcinoma30.8MME, MET, VHL, CA9, HNF1B, OGG1
7von hippel-lindau syndrome30.8MET, VHL
8renal clear cell carcinoma30.7CA9, VHL, MET, MME
9polycystic kidney disease30.7HNF1B, VHL
10alveolar soft-part sarcoma30.6TFE3, ASPSCR1, PRCC
11papillary adenoma30.6PRCC
12cystadenoma30.6MME, VHL
13hepatocellular carcinoma30.6MME, MET, HNF1B, HNF1A, OGG1
14colorectal cancer30.6MET, CA9, HNF1A, OGG1
15birt-hogg-dube syndrome30.5FLCN
16breast cancer30.4MME, MET, VHL, CA9, HNF1A, OGG1
17cholangiocarcinoma30.2MME, MET, OGG1
18clear cell renal cell carcinoma11.4
19chromophobe renal cell carcinoma11.2
20sarcomatoid renal cell carcinoma11.1
22clear cell papillary renal cell carcinoma10.9
23multilocular cystic renal cell carcinoma10.9
27translocation renal cell carcinoma10.8
28renal cell carcinoma, papillary10.8
29kidney disease10.8
30familial renal cell carcinoma10.8
32hereditary renal cell carcinoma10.7
33horseshoe kidney10.7
36tuberous sclerosis10.6
38xanthogranulomatous pyelonephritis10.6
39chromophil renal cell carcinoma10.6
42collecting duct carcinoma10.6
47paraneoplastic syndromes10.5
49renal cell carcinoma 410.5
50mucinous tubular and spindle cell carcinoma10.5

Graphical network of the top 20 diseases related to Renal Cell Carcinoma:

Diseases related to renal cell carcinoma

Symptoms for Renal Cell Carcinoma

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Clinical features from OMIM:


HPO human phenotypes related to Renal Cell Carcinoma:

id Description Frequency HPO Source Accession
1 sporadic HP:0003745
2 renal cell carcinoma HP:0005584

Drugs & Therapeutics for Renal Cell Carcinoma

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Genetic Tests for Renal Cell Carcinoma

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Genetic tests related to Renal Cell Carcinoma:

id Genetic test Affiliating Genes
1 Renal Cell Carcinoma, Nonpapillary24

Anatomical Context for Renal Cell Carcinoma

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MalaCards organs/tissues related to Renal Cell Carcinoma:

Kidney, Endothelial, T cells, Bone, Thyroid, Liver, Lung, Prostate, Brain, Breast, Lymph node, Myeloid, Skin, Monocytes, Testes, B cells, Testis, Neutrophil, Cortex, Pituitary, Smooth muscle, Bone marrow, Heart, Colon, Pancreas, Nk cells, Spinal cord, Small intestine, Adrenal gland, Tongue, Whole blood, Spleen, Skeletal muscle, Salivary gland, Ovary, Placenta

Animal Models for Renal Cell Carcinoma or affiliated genes

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MGI Mouse Phenotypes related to Renal Cell Carcinoma:

idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537010.5OGG1, MME, PBRM1, MET, VHL, HNF1B
2MP:000536710.5HNF1A, HNF1B, VHL, MET, FLCN
3MP:001076810.4TFE3, FLCN, PBRM1, MET, VHL, CA9
4MP:000538010.3FLCN, PBRM1, MET, VHL, HNF1B, NONO
5MP:000537610.1FLCN, MME, MET, VHL, HNF1B, HNF1A

Publications for Renal Cell Carcinoma

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Articles related to Renal Cell Carcinoma:

(show top 50)    (show all 4337)
Small tumour size is associated with new-onset chronic kidney disease after radical nephrectomy in patients with renal cell carcinoma. (24060356)
Comparative expression profiling for human endoplasmic reticulum-resident aminopeptidases 1 and 2 in normal kidney versus distinct renal cell carcinoma subtypes. (23696916)
Words of wisdom: re: multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects. (23272732)
Attenuation of krA1ppel-like factor 4 facilitates carcinogenesis by inducing g1/s phase arrest in clear cell renal cell carcinoma. (23861801)
Effects of TGF-I^ signaling in clear cell renal cell carcinoma cells. (23618868)
Double jeopardy? Renal-sparing management of simultaneous ipsilateral renal cell carcinoma and urothelial carcinoma. (23914271)
Polypeptide N-acetylgalactosaminyl transferase 3 independently predicts high-grade tumours and poor prognosis in patients with renal cell carcinomas. (23799843)
Fibronectin 1 protein expression in clear cell renal cell carcinoma. (22740994)
Alterations of the WNT7A gene in clear cell renal cell carcinomas. (23056560)
Specific miRNA signatures are associated with metastasis and poor prognosis in clear cell renal cell carcinoma. (21229250)
A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma. (21632985)
Progress in nephron sparing therapy for renal cell carcinoma and von Hippel-Lindau disease. (21496837)
Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. (20103651)
Combined blood/tissue analysis for cancer biomarker discovery: application to renal cell carcinoma. (20121140)
A proposal for reclassification of the Fuhrman grading system in patients with clear cell renal cell carcinoma. (19573980)
Increased activated Akt expression in renal cell carcinomas and prognosis. (18774962)
Imprint cytologic features in renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusion in an adult: a case report. (20014561)
Onconeuronal cerebellar degeneration-related antigen, Cdr2, is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response. (19581925)
MMP-13 is over-expressed in renal cell carcinoma bone metastasis and is induced by TGF-beta1. (18709334)
Renal cell carcinoma and antiangiogenic therapies]. (18035517)
Organ-confined clear cell renal cell carcinoma: the prognostic impact of microvascular invasion, nuclear grade and tumour size. (19133004)
Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins. (17605814)
Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element. (16644575)
Renal cell carcinoma with an Xp11.2 translocation in a 16-year-old girl: a case report with cytological features. (17121199)
Chromophobe renal cell carcinoma with focal papillary configuration, nuclear basaloid arrangement and stromal osseous metaplasia containing fatty bone marrow element. (15910607)
Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma. (15625368)
Experimental study on induction of renal cell carcinoma apoptosis by antisense oligonucleotide targeting survivin. (15641694)
Expression of 12-lipoxygenase in human renal cell carcinoma and growth prevention by its inhibitor. (14654968)
Disruption of basement membrane, extracellular matrix metalloproteinases and E-cadherin in renal-cell carcinoma. (14981959)
Analysis of the structural integrity of the TAP2 gene in renal cell carcinoma. (12963978)
Interleukin-6, tumour necrosis factor alpha and interleukin-1beta in patients with renal cell carcinoma. (11986770)
Proliferating cell nuclear antigen and epidermal growth factor receptor (EGFr) status in renal cell carcinoma patients with polysomy of chromosome 7. (11369057)
Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan. (11139287)
Interferon-gamma and CXC chemokine induction by interleukin 12 in renal cell carcinoma. (10537342)
Loss of imprinting of the insulin-like growth factor II gene in renal cell carcinoma. (9205056)
Temporal arteritis presenting with concomitant renal cell carcinoma. (19078210)
An improved circularly permuted interleukin 4-toxin is highly cytotoxic to human renal cell carcinoma cells. Introduction of gamma c chain in RCC cells does not improve sensitivity. (8660841)
Inhibitory effect of dexamethasone and progesterone in vitro on proliferation of human renal cell carcinomas and effects on expression of interleukin-6 or interleukin-6 receptor. (7861551)
Subcutaneous low-dose recombinant interleukin 2 and alpha-interferon in patients with metastatic renal cell carcinoma. (8198979)
Sarcomatoid renal cell carcinoma. A study of its proliferative activity. (8095849)
Immunological study of interferon-gamma therapy for advanced renal cell carcinoma]. (1288223)
Cytokine-induced gene expression of interleukin-8 in human transitional cell carcinomas and renal cell carcinomas. (1739130)
Immune modulating effects of low doses of cyclophosphamide and keyhole limpet hemocyanin on peripheral blood immune parameters in patients with metastatic renal cell carcinoma. (1598724)
Ifosfamide, vindesine and recombinant alpha-interferon combination chemotherapy for metastatic renal cell carcinoma. (1795011)
In vivo antiproliferative effects of gamma-interferon and tumor necrosis factor alpha in a rat renal cell carcinoma model system. (2111411)
Comparative biochemical and immunological studies on gamma-glutamyltransferases from human kidney and renal cell carcinoma applying monoclonal antibodies. (1979761)
Recombinant leukocyte interferon alpha-2a and medroxyprogesterone in advanced renal cell carcinoma. A randomized trial. (2185803)
Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma. (2894030)
Reversible renal hypertension secondary to renal arteriovenous fistula and renal cell carcinoma. (833981)

Variations for Renal Cell Carcinoma

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UniProtKB/Swiss-Prot genetic disease variations for Renal Cell Carcinoma:

id Symbol AA change Variation ID SNP ID

Cosmic variations for Renal Cell Carcinoma:

8 (show all 89)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
114312VHLkidney,NS,carcinoma,renal cell carcinoma3
218346VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
317807VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
414311VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
517983VHLkidney,NS,carcinoma,renal cell carcinoma3
614284VHLkidney,NS,carcinoma,renal cell carcinoma3
717957VHLkidney,NS,carcinoma,renal cell carcinoma3
830286VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
925673VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
1017808VHLkidney,NS,carcinoma,papillary renal cell carcinoma3
1114382VHLkidney,NS,carcinoma,renal cell carcinoma3
1218028VHLkidney,NS,carcinoma,chromophobe renal cell carcinoma3
1330410VHLkidney,NS,carcinoma,renal cell carcinoma3
1410670TP53kidney,NS,carcinoma,chromophobe renal cell carcinoma3
1510659TP53kidney,NS,carcinoma,chromophobe renal cell carcinoma3
1611984TP53kidney,NS,carcinoma,renal cell carcinoma3
1710709TP53kidney,NS,carcinoma,papillary renal cell carcinoma3
1845322TP53kidney,NS,carcinoma,chromophobe renal cell carcinoma3
1911450TP53kidney,NS,carcinoma,chromophobe renal cell carcinoma3
2043697TP53kidney,NS,carcinoma,papillary renal cell carcinoma3
2111071TP53kidney,NS,carcinoma,chromophobe renal cell carcinoma3
2210656TP53kidney,NS,carcinoma,renal cell carcinoma3
2310648TP53kidney,NS,carcinoma,renal cell carcinoma3
2443850TP53kidney,NS,carcinoma,papillary renal cell carcinoma3
25690METkidney,NS,carcinoma,papillary renal cell carcinoma3
26704METkidney,NS,carcinoma,papillary renal cell carcinoma3
27698METkidney,NS,carcinoma,papillary renal cell carcinoma3
28689METkidney,NS,carcinoma,papillary renal cell carcinoma3
29484661METkidney,NS,carcinoma,papillary renal cell carcinoma3
30697METkidney,NS,carcinoma,papillary renal cell carcinoma3
31696METkidney,NS,carcinoma,papillary renal cell carcinoma3
32688METkidney,NS,carcinoma,papillary renal cell carcinoma3
33691METkidney,NS,carcinoma,papillary renal cell carcinoma3
34718FGFR3kidney,NS,carcinoma,papillary renal cell carcinoma3
353993568FGFR3kidney,NS,carcinoma,papillary renal cell carcinoma3
361676793KRASkidney,NS,carcinoma,renal cell carcinoma3
37521KRASkidney,NS,carcinoma,papillary renal cell carcinoma3
38462BRAFkidney,NS,carcinoma,papillary renal cell carcinoma3
391131BRAFkidney,NS,carcinoma,papillary renal cell carcinoma3
40760PIK3CAkidney,NS,carcinoma,papillary renal cell carcinoma3
41763PIK3CAkidney,NS,carcinoma,papillary renal cell carcinoma3
42307445GIT2kidney,NS,carcinoma,renal cell carcinoma3
431677336GIT2kidney,NS,carcinoma,renal cell carcinoma3
441683084FBXW4kidney,NS,carcinoma,renal cell carcinoma3
451682757KLHL4kidney,NS,carcinoma,renal cell carcinoma3
4614060ERBB2kidney,NS,carcinoma,papillary renal cell carcinoma3
4721945EGFRkidney,NS,carcinoma,papillary renal cell carcinoma3
481680669EPORkidney,NS,carcinoma,renal cell carcinoma3
491675310HKDC1kidney,NS,carcinoma,renal cell carcinoma3
5022853E2F7kidney,NS,carcinoma,renal cell carcinoma3
511682806GUCY2Fkidney,NS,carcinoma,renal cell carcinoma3
52188258HIVEP3kidney,NS,carcinoma,papillary renal cell carcinoma3
53742462GFRALkidney,NS,carcinoma,papillary renal cell carcinoma3
541670294FLNBkidney,NS,carcinoma,renal cell carcinoma3
5524266DGKIkidney,NS,carcinoma,renal cell carcinoma3
56375284ANKHD1kidney,NS,carcinoma,papillary renal cell carcinoma3
57375283ANKHD1-EIF4EBP3kidney,NS,carcinoma,papillary renal cell carcinoma3
581671070ANKRD17kidney,NS,carcinoma,renal cell carcinoma3
591671225ANK2kidney,NS,carcinoma,renal cell carcinoma3
6022805ADAM7kidney,NS,carcinoma,renal cell carcinoma3
611181978ADARB1kidney,NS,carcinoma,papillary renal cell carcinoma3
6225413ANKRD60kidney,NS,carcinoma,renal cell carcinoma3
631681624CBFA2T2kidney,NS,carcinoma,renal cell carcinoma3
64302052DHX9kidney,NS,carcinoma,papillary renal cell carcinoma3
651583146DNMT3Akidney,NS,carcinoma,papillary renal cell carcinoma3
6613489CDKN2Akidney,NS,carcinoma,renal cell carcinoma3
671683097CDC42BPBkidney,NS,carcinoma,renal cell carcinoma3
68274461CDC73kidney,NS,carcinoma,papillary renal cell carcinoma3
691676177DPF2kidney,NS,carcinoma,renal cell carcinoma3
7021103ROR1kidney,NS,carcinoma,renal cell carcinoma3
711669645SATB2kidney,NS,carcinoma,renal cell carcinoma3
72487039SCAIkidney,NS,carcinoma,papillary renal cell carcinoma3
73485065RHEBkidney,NS,carcinoma,papillary renal cell carcinoma3
741222993RAD23Bkidney,NS,carcinoma,papillary renal cell carcinoma3
751675206RBP3kidney,NS,carcinoma,renal cell carcinoma3
761675176RETkidney,NS,carcinoma,renal cell carcinoma3
7724274SMAD4kidney,NS,carcinoma,renal cell carcinoma3
78110414SMARCB1kidney,NS,carcinoma,papillary renal cell carcinoma3
791268384TP63kidney,NS,carcinoma,papillary renal cell carcinoma3
8025383TRPA1kidney,NS,carcinoma,renal cell carcinoma3
811683057TTF2kidney,NS,carcinoma,renal cell carcinoma3
821674226ZFP41kidney,NS,carcinoma,renal cell carcinoma3
831360764SOX5kidney,NS,carcinoma,papillary renal cell carcinoma3
841683105TEX14kidney,NS,carcinoma,renal cell carcinoma3
85322959RAB3Ckidney,NS,carcinoma,renal cell carcinoma3
8621092NEK6kidney,NS,carcinoma,renal cell carcinoma3
87163384PDGFRAkidney,NS,carcinoma,papillary renal cell carcinoma3
881680798PIK3R2kidney,NS,carcinoma,renal cell carcinoma3
8927222MMP2kidney,NS,carcinoma,renal cell carcinoma3
901680950ZNF383kidney,NS,carcinoma,renal cell carcinoma3
911677789LIG4kidney,NS,carcinoma,renal cell carcinoma3
92964299MAP2K5kidney,NS,carcinoma,papillary renal cell carcinoma3
931669602WDR75kidney,NS,carcinoma,renal cell carcinoma3
9421735PMLkidney,NS,carcinoma,renal cell carcinoma3
95485575PMS2P11kidney,NS,carcinoma,papillary renal cell carcinoma3
961683107PTPRMkidney,NS,carcinoma,renal cell carcinoma3
971681684PTPRTkidney,NS,carcinoma,renal cell carcinoma3
981682139RAB36kidney,NS,carcinoma,renal cell carcinoma3
991673226PTPN12kidney,NS,carcinoma,renal cell carcinoma3
1001677360PTPN11kidney,NS,carcinoma,renal cell carcinoma3
10123140PPP1R10kidney,NS,carcinoma,renal cell carcinoma3
10221847PREX2kidney,NS,carcinoma,renal cell carcinoma3
1035260PTENkidney,NS,carcinoma,papillary renal cell carcinoma3

Expression for genes affiliated with Renal Cell Carcinoma

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LifeMap Discovery
Genes differentially expressed in tissues of Renal Cell Carcinoma patients vs. healthy controls: 32 (show all 320)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1ANGPTL4angiopoietin-like 4Kidney+7.250.000
2TNFAIP6tumor necrosis factor, alpha-induced protein 6Kidney+7.160.000
3APOC1apolipoprotein C-IKidney+6.110.000
4NPTX2neuronal pentraxin IIKidney+6.050.000
5PTHLHparathyroid hormone-like hormoneKidney+5.880.001
6NDUFA4L2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2Kidney+5.760.000
7FABP7fatty acid binding protein 7, brainKidney+5.710.042
8CCL20chemokine (C-C motif) ligand 20Kidney+5.550.007
9CDCA2cell division cycle associated 2Kidney+5.520.000
10STC2stanniocalcin 2Kidney+5.390.000
11TOP2Atopoisomerase (DNA) II alpha 170kDaKidney+5.240.000
12EGLN3egl-9 family hypoxia-inducible factor 3Kidney+5.120.000
13NKG7natural killer cell granule protein 7Kidney+5.070.000
14NNMTnicotinamide N-methyltransferaseKidney+5.050.000
15FABP6fatty acid binding protein 6, ilealKidney+4.940.005
16CA9carbonic anhydrase IXKidney+4.920.000
17ISG20interferon stimulated exonuclease gene 20kDaKidney+4.890.000
18HK2hexokinase 2Kidney+4.710.000
19KISS1RKISS1 receptorKidney+4.670.001
20ARL11ADP-ribosylation factor-like 11Kidney+4.600.000
21C5orf46chromosome 5 open reading frame 46Kidney+4.590.016
22C3complement component 3Kidney+4.550.000
23CTHRC1collagen triple helix repeat containing 1Kidney+4.540.000
24CD300ACD300a moleculeKidney+4.490.001
25CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)Kidney+4.450.012
26SLAMF7SLAM family member 7Kidney+4.450.001
27MIR155HGMIR155 host gene (non-protein coding)Kidney+4.440.001
28SLFN13schlafen family member 13Kidney+4.320.000
29SLC16A3solute carrier family 16 (monocarboxylate transporter), member 3Kidney+4.240.000
30FAM26Ffamily with sequence similarity 26, member FKidney+4.180.000
31SPAG4sperm associated antigen 4Kidney+4.130.000
32EHD2EH-domain containing 2Kidney+4.120.000
33CXCL9chemokine (C-X-C motif) ligand 9Kidney+4.110.001
34LOXlysyl oxidaseKidney+4.100.000
35CCNE2cyclin E2Kidney+4.080.000
36ENO2enolase 2 (gamma, neuronal)Kidney+4.080.000
37COL23A1collagen, type XXIII, alpha 1Kidney+4.030.003
38RGS1regulator of G-protein signaling 1Kidney+4.030.000
39CD86CD86 moleculeKidney+3.990.000
40CYP2J2cytochrome P450, family 2, subfamily J, polypeptide 2Kidney+3.990.023
41HAPLN1hyaluronan and proteoglycan link protein 1Kidney+3.980.009
42TLR8toll-like receptor 8Kidney+3.980.000
43ST8SIA4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4Kidney+3.900.000
44AHNAK2AHNAK nucleoprotein 2Kidney+3.900.000
45RLTPRRGD motif, leucine rich repeats, tropomodulin domain and proline-rich containingBlood-3.890.000
46BIRC3baculoviral IAP repeat containing 3Kidney+3.880.000
47TTKTTK protein kinaseKidney+3.880.000
48HIST1H2AGhistone cluster 1, H2agKidney+3.870.007
49LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2Kidney+3.870.000
50LOC100289026putative uncharacterized protein FLJ00310-likeKidney+3.860.006
51C4orf47chromosome 4 open reading frame 47Kidney+3.850.000
52CD248CD248 molecule, endosialinBlood-3.840.000
53INHBBinhibin, beta BKidney+3.840.001
54PLA2G7phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)Kidney+3.840.003
55CPceruloplasmin (ferroxidase)Kidney+3.830.021
56BRIP1BRCA1 interacting protein C-terminal helicase 1Kidney+3.830.003
57HMHA1histocompatibility (minor) HA-1Kidney+3.830.000
58GAS2L3growth arrest-specific 2 like 3Kidney+3.830.000
59SPIBSpi-B transcription factor (Spi-1/PU.1 related)Blood-3.810.000
60TEX11testis expressed 11Kidney+3.790.029
61HILPDAhypoxia inducible lipid droplet-associatedKidney+3.790.000
62TREM2triggering receptor expressed on myeloid cells 2Kidney+3.790.000
63BHLHE41basic helix-loop-helix family, member e41Kidney+3.720.000
64TMCC1transmembrane and coiled-coil domain family 1Kidney+3.720.000
65KIF20Akinesin family member 20AKidney+3.720.000
66TPX2TPX2, microtubule-associatedKidney+3.700.000
67LRRN3leucine rich repeat neuronal 3Blood-3.610.000
68AEBP1AE binding protein 1Blood-3.530.000
69LGALSLlectin, galactoside-binding-likeBlood-3.430.000
70PLEKHB1pleckstrin homology domain containing, family B (evectins) member 1Blood-3.400.000
71CD22CD22 moleculeBlood-3.380.000
72EPHB6EPH receptor B6Blood-3.300.000
73MVDmevalonate (diphospho) decarboxylaseBlood-3.260.000
74FBLN2fibulin 2Blood-3.260.000
75FBXL16F-box and leucine-rich repeat protein 16Blood-3.230.000
76CR2complement component (3d/Epstein Barr virus) receptor 2Blood-3.210.000
77PRSS33protease, serine, 33Blood-3.210.000
78GNPNAT1glucosamine-phosphate N-acetyltransferase 1Blood-3.190.000
79RTKN2rhotekin 2Blood-3.190.000
80EPHA1EPH receptor A1Blood-3.160.000
81CRIP2cysteine-rich protein 2Blood-3.150.000
82SERINC5serine incorporator 5Blood-3.120.000
83HKDC1hexokinase domain containing 1Blood-3.110.000
84NT5E5'-nucleotidase, ecto (CD73)Blood-3.100.000
85PMEPA1prostate transmembrane protein, androgen induced 1Blood-3.090.000
86FCGBPFc fragment of IgG binding proteinBlood-3.070.000
87SALL2spalt-like transcription factor 2Blood-3.060.000
88GPA33glycoprotein A33 (transmembrane)Blood-3.020.000
89SLC27A5solute carrier family 27 (fatty acid transporter), member 5Blood-3.000.000
90ZSCAN12zinc finger and SCAN domain containing 12Blood-2.970.000
91ANKS3ankyrin repeat and sterile alpha motif domain containing 3Blood-2.970.000
92OLIG2oligodendrocyte lineage transcription factor 2Blood-2.970.001
93OSBPL10oxysterol binding protein-like 10Blood-2.970.000
94MRPL2mitochondrial ribosomal protein L2Blood-2.960.000
95SEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4FBlood-2.930.000
96MEI1meiosis inhibitor 1Blood-2.920.000
97KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologBlood-2.920.000
98NELL2NEL-like 2 (chicken)Blood-2.920.000
99ABCF2ATP-binding cassette, sub-family F (GCN20), member 2Blood-2.910.000
101DTX3deltex 3, E3 ubiquitin ligaseBlood-2.890.000
102C10orf35chromosome 10 open reading frame 35Blood-2.870.000
103PLEKHG4pleckstrin homology domain containing, family G (with RhoGef domain) member 4Blood-2.870.000
104CD3DCD3d molecule, delta (CD3-TCR complex)Blood-2.860.000
105CBR3carbonyl reductase 3Blood-2.860.000
106HPCAL4hippocalcin like 4Blood-2.850.000
107FAM102Afamily with sequence similarity 102, member ABlood-2.850.000
108SPRY1sprouty homolog 1, antagonist of FGF signaling (Drosophila)Blood-2.840.000
109FHITfragile histidine triadBlood-2.840.000
110GLI4GLI family zinc finger 4Blood-2.840.000
111IL23Ainterleukin 23, alpha subunit p19Blood-2.840.000
112BLKB lymphoid tyrosine kinaseBlood-2.830.000
114CD3ECD3e molecule, epsilon (CD3-TCR complex)Blood-2.810.000
115OLFM1olfactomedin 1Blood-2.800.000
116PKD1polycystic kidney disease 1 (autosomal dominant)Blood-2.800.000
117GSTT1glutathione S-transferase theta 1Blood-2.800.005
118MCM2minichromosome maintenance complex component 2Blood-2.790.000
119SELMselenoprotein MBlood-2.780.000
120ASTN2astrotactin 2Blood-2.780.000
121HSF5heat shock transcription factor family member 5Blood-2.770.000
122CSRP2BPCSRP2 binding proteinBlood-2.770.000
124SIRPGsignal-regulatory protein gammaBlood-2.770.001
125NRCAMneuronal cell adhesion moleculeBlood-2.760.002
126RLN2relaxin 2Blood-2.760.000
127THOP1thimet oligopeptidase 1Blood-2.750.000
128HAPLN3hyaluronan and proteoglycan link protein 3Blood-2.740.000
129RFX7regulatory factor X, 7Blood-2.730.000
130ZNF285zinc finger protein 285Blood-2.720.000
131ZNF239zinc finger protein 239Blood-2.720.000
132SLC29A2solute carrier family 29 (equilibrative nucleoside transporter), member 2Blood-2.710.000
133C16orf74chromosome 16 open reading frame 74Blood-2.710.000
134TFAP4transcription factor AP-4 (activating enhancer binding protein 4)Blood-2.710.000
135RRP9ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)Blood-2.700.000
136ST8SIA1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1Blood-2.700.000
137PLXNA3plexin A3Blood-2.700.000
138CHCHD6coiled-coil-helix-coiled-coil-helix domain containing 6Blood-2.690.000
139CD79ACD79a molecule, immunoglobulin-associated alphaBlood-2.690.000
140ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix proteinBlood-2.690.000
141NOVnephroblastoma overexpressedBlood-2.690.000
142TRIM47tripartite motif containing 47Blood-2.680.000
143NAT6N-acetyltransferase 6 (GCN5-related)Blood-2.670.000
144TMEM204transmembrane protein 204Blood-2.670.000
145MYO1Cmyosin ICBlood-2.650.000
146JOSD2Josephin domain containing 2Blood-2.650.000
147CA11carbonic anhydrase XIBlood-2.650.000
148COX11cytochrome c oxidase assembly homolog 11 (yeast)Blood-2.630.000
149VPREB3pre-B lymphocyte 3Blood-2.630.000
150DCTN1dynactin 1Blood-2.630.000
151COL9A2collagen, type IX, alpha 2Blood-2.630.000
152SIGLEC17Psialic acid binding Ig-like lectin 17, pseudogeneBlood-2.620.000
153ELOVL4ELOVL fatty acid elongase 4Blood-2.600.000
154CD8BCD8b moleculeBlood-2.590.000
155EFHD1EF-hand domain family, member D1Blood-2.590.000
156ZNF404zinc finger protein 404Blood-2.590.000
157GATA3GATA binding protein 3Blood-2.590.000
158AHDC1AT hook, DNA binding motif, containing 1Blood-2.590.000
159GAMTguanidinoacetate N-methyltransferaseBlood-2.590.000
160COL6A2collagen, type VI, alpha 2Blood-2.580.001
161EDARectodysplasin A receptorBlood-2.580.000
162MAP7microtubule-associated protein 7Blood-2.580.000
163ELP5elongator acetyltransferase complex subunit 5Blood-2.570.000
164VIPR1vasoactive intestinal peptide receptor 1Blood-2.570.000
165CCL28chemokine (C-C motif) ligand 28Blood-2.570.000
166PTPDC1protein tyrosine phosphatase domain containing 1Blood-2.570.000
167THAP7THAP domain containing 7Blood-2.560.000
168SLC16A10solute carrier family 16 (aromatic amino acid transporter), member 10Blood-2.560.000
169PTPRKprotein tyrosine phosphatase, receptor type, KBlood-2.560.000
170TSHZ2teashirt zinc finger homeobox 2Blood-2.550.000
171SPPL2Bsignal peptide peptidase like 2BBlood-2.540.001
172BEND5BEN domain containing 5Blood-2.530.000
173SH2D3ASH2 domain containing 3ABlood-2.530.000
174CCDC124coiled-coil domain containing 124Blood-2.520.000
175NUDT8nudix (nucleoside diphosphate linked moiety X)-type motif 8Blood-2.520.000
176LPHN1latrophilin 1Blood-2.510.000
177CACNA2D3calcium channel, voltage-dependent, alpha 2/delta subunit 3Blood-2.510.000
178DBNDD1dysbindin (dystrobrevin binding protein 1) domain containing 1Blood-2.510.001
179EPN2epsin 2Blood-2.510.000
180SPINK2serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)Blood-2.510.000
181LINC00883long intergenic non-protein coding RNA 883Blood-2.510.001
182PASKPAS domain containing serine/threonine kinaseBlood-2.500.000
183BDH13-hydroxybutyrate dehydrogenase, type 1Blood-2.500.000
184GOLGA7Bgolgin A7 family, member BBlood-2.500.000
185FAM171A1family with sequence similarity 171, member A1Blood-2.500.000
186TRABD2BTraB domain containing 2BBlood-2.490.000
187LDLRAD4low density lipoprotein receptor class A domain containing 4Blood-2.490.000
188DCHS1dachsous cadherin-related 1Blood-2.480.001
189FRMPD3FERM and PDZ domain containing 3Blood-2.470.000
190LYPD2LY6/PLAUR domain containing 2Blood-2.470.000
191SLC25A17solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17Blood-2.470.000
192CD5CD5 moleculeBlood-2.470.000
193CNN3calponin 3, acidicBlood-2.470.000
194NPR2natriuretic peptide receptor 2Blood-2.460.000
195NLGN2neuroligin 2Blood-2.460.000
196FAIM3Fas apoptotic inhibitory molecule 3Blood-2.460.000
197SHISA2shisa family member 2Blood-2.460.000
198WDR27WD repeat domain 27Blood-2.460.000
199SORBS3sorbin and SH3 domain containing 3Blood-2.460.000
200ODF2outer dense fiber of sperm tails 2Blood-2.460.000
201DNHD1dynein heavy chain domain 1Blood-2.450.000
202LRIG1leucine-rich repeats and immunoglobulin-like domains 1Blood-2.450.000
203XRCC3X-ray repair complementing defective repair in Chinese hamster cells 3Blood-2.450.001
204DBPD site of albumin promoter (albumin D-box) binding proteinBlood-2.440.000
205EBF1early B-cell factor 1Blood-2.440.000
206CD19CD19 moleculeBlood-2.440.000
207CREB3L4cAMP responsive element binding protein 3-like 4Blood-2.440.000
208SPON1spondin 1, extracellular matrix proteinBlood-2.430.000
209GDF11growth differentiation factor 11Blood-2.430.000
210ICOSLGinducible T-cell co-stimulator ligandBlood-2.420.000
211RHOFras homolog family member F (in filopodia)Blood-2.410.000
212CNTNAP2contactin associated protein-like 2Blood-2.410.023
213PPP2R3Bprotein phosphatase 2, regulatory subunit B'', betaBlood-2.410.000
214SMIM8small integral membrane protein 8Blood-2.410.000
215RECQL5RecQ protein-like 5Blood-2.400.000
216CHST14carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14Blood-2.400.000
217TRIM46tripartite motif containing 46Blood-2.400.000
218POU2AF1POU class 2 associating factor 1Blood-2.400.000
219FAM184Afamily with sequence similarity 184, member ABlood-2.390.000
220ZNF649zinc finger protein 649Blood-2.390.000
221MOB3BMOB kinase activator 3BBlood-2.390.000
222SLC25A3P1solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 pseudogene 1Blood-2.390.000
223GRWD1glutamate-rich WD repeat containing 1Blood-2.390.000
224TRIM65tripartite motif containing 65Blood-2.390.000
225PDCD1programmed cell death 1Blood-2.380.000
226FCRLAFc receptor-like ABlood-2.380.000
227LCKlymphocyte-specific protein tyrosine kinaseBlood-2.370.000
228CD27CD27 moleculeBlood-2.370.000
229ZNF574zinc finger protein 574Blood-2.360.001
230ZNF502zinc finger protein 502Blood-2.350.003
231ATP6V0E2-AS1ATP6V0E2 antisense RNA 1Blood-2.350.001
232WNT10Bwingless-type MMTV integration site family, member 10BBlood-2.350.000
233LTBP4latent transforming growth factor beta binding protein 4Blood-2.350.000
234SLC22A23solute carrier family 22, member 23Blood-2.340.000
235ZC3H12Bzinc finger CCCH-type containing 12BBlood-2.340.000
236CYP2S1cytochrome P450, family 2, subfamily S, polypeptide 1Blood-2.340.001
237COL4A3collagen, type IV, alpha 3 (Goodpasture antigen)Blood-2.340.000
238CD79BCD79b molecule, immunoglobulin-associated betaBlood-2.340.000
239OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEFBlood-2.330.012
240SPTAN1spectrin, alpha, non-erythrocytic 1Blood-2.330.000
241GNG7guanine nucleotide binding protein (G protein), gamma 7Blood-2.330.000
242LINC01181long intergenic non-protein coding RNA 1181Blood-2.330.002
243AHI1Abelson helper integration site 1Blood-2.330.000
244SPSB1splA/ryanodine receptor domain and SOCS box containing 1Blood-2.330.002
245SNTA1syntrophin, alpha 1Blood-2.320.000
246IGFBP4insulin-like growth factor binding protein 4Blood-2.320.002
247KLHL34kelch-like family member 34Blood-2.320.008
248SIRT4sirtuin 4Blood-2.320.000
249DPH7diphthamide biosynthesis 7Blood-2.320.000
250HSD17B3hydroxysteroid (17-beta) dehydrogenase 3Blood-2.310.000
251DYRK1Bdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1BBlood-2.310.000
252PLSCR3phospholipid scramblase 3Blood-2.310.002
253MAN1C1mannosidase, alpha, class 1C, member 1Blood-2.310.000
254OLIG1oligodendrocyte transcription factor 1Blood-2.300.000
255FZD3frizzled class receptor 3Blood-2.300.000
256POLR3Dpolymerase (RNA) III (DNA directed) polypeptide D, 44kDaBlood-2.300.001
257C12orf57chromosome 12 open reading frame 57Blood-2.300.000
258URB2URB2 ribosome biogenesis 2 homolog (S. cerevisiae)Blood-2.300.000
259GCSAMgerminal center-associated, signaling and motilityBlood-2.300.000
260MMP23Amatrix metallopeptidase 23A (pseudogene)Blood-2.300.000
261ABLIM1actin binding LIM protein 1Blood-2.290.000
262RFC3replication factor C (activator 1) 3, 38kDaBlood-2.290.000
263AXIN2axin 2Blood-2.290.000
264ACSL4acyl-CoA synthetase long-chain family member 4Blood+1.780.006
265GPR84G protein-coupled receptor 84Blood+1.780.016
266STAT1signal transducer and activator of transcription 1, 91kDaBlood+1.780.000
267IL27interleukin 27Blood+1.770.029
268DDX17DEAD (Asp-Glu-Ala-Asp) box helicase 17Blood+1.770.008
269MRPL42P5mitochondrial ribosomal protein L42 pseudogene 5Blood+1.760.017
270CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)Blood+1.760.001
271PAK2p21 protein (Cdc42/Rac)-activated kinase 2Blood+1.760.017
272LIMS1LIM and senescent cell antigen-like domains 1Blood+1.750.023
273SF3B1splicing factor 3b, subunit 1, 155kDaBlood+1.750.002
274FAM21Bfamily with sequence similarity 21, member BBlood+1.750.003
275PSPHP1phosphoserine phosphatase pseudogene 1Blood+1.740.024
276ASB7ankyrin repeat and SOCS box containing 7Blood+1.740.017
277TLR8toll-like receptor 8Blood+1.740.032
278MEF2Amyocyte enhancer factor 2ABlood+1.740.000
279PRDM5PR domain containing 5Blood+1.730.033
280KLF10Kruppel-like factor 10Blood+1.720.010
281HIST1H3Ehistone cluster 1, H3eBlood+1.720.016
282RPS6KA3ribosomal protein S6 kinase, 90kDa, polypeptide 3Blood+1.720.021
283SLCO3A1solute carrier organic anion transporter family, member 3A1Blood+1.720.011
284ARFIP1ADP-ribosylation factor interacting protein 1Blood+1.720.003
285RMDN1regulator of microtubule dynamics 1Blood+1.710.011
286WNT2Bwingless-type MMTV integration site family, member 2BBlood+1.710.019
287RBBP8retinoblastoma binding protein 8Blood+1.710.023
288VNN3vanin 3Blood+1.710.006
289SRGAP2SLIT-ROBO Rho GTPase activating protein 2Blood+1.700.012
290BZW1basic leucine zipper and W2 domains 1Blood+1.700.008
291ATRXalpha thalassemia/mental retardation syndrome X-linkedBlood+1.700.008
292LYSTlysosomal trafficking regulatorBlood+1.690.046
293LOC390933protein associated with topoisomerase II homolog 1 (yeast) pseudogeneBlood+1.690.002
294CFBcomplement factor BBlood+1.690.007
295SUCNR1succinate receptor 1Blood+1.680.023
296ERC1ELKS/RAB6-interacting/CAST family member 1Blood+1.670.032
297SAMD9Lsterile alpha motif domain containing 9-likeBlood+1.670.001
298PRRG4proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)Blood+1.670.006
299IFI44interferon-induced protein 44Blood+1.670.007
300ZAKsterile alpha motif and leucine zipper containing kinase AZKBlood+1.660.008
301AC018470.4uncharacterized LOC285084Blood+1.660.018
302LOC728519NLR family, apoptosis inhibitory protein pseudogeneBlood+1.660.002
303BCLAF1BCL2-associated transcription factor 1Blood+1.640.025
304GCNT2glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)Blood+1.640.033
305SOCS3suppressor of cytokine signaling 3Blood+1.640.009
306FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligaseBlood+1.630.033
307IVNS1ABPinfluenza virus NS1A binding proteinBlood+1.630.038
308CPEB4cytoplasmic polyadenylation element binding protein 4Blood+1.630.003
309PIK3AP1phosphoinositide-3-kinase adaptor protein 1Blood+1.620.001
310CDKL5cyclin-dependent kinase-like 5Blood+1.620.007
311TOR1AIP2torsin A interacting protein 2Blood+1.620.015
312GNB4guanine nucleotide binding protein (G protein), beta polypeptide 4Blood+1.610.017
313ARHGAP25Rho GTPase activating protein 25Blood+1.610.007
314SCN9Asodium channel, voltage-gated, type IX, alpha subunitBlood+1.600.041
315LBRlamin B receptorBlood+1.600.020
316MAPK10mitogen-activated protein kinase 10Blood+1.600.046
317MCTP2multiple C2 domains, transmembrane 2Blood+1.580.002
318GTF2A1general transcription factor IIA, 1, 19/37kDaBlood+1.580.038
319MBNL3muscleblind-like splicing regulator 3Blood+1.580.046
320ELF2E74-like factor 2 (ets domain transcription factor)Blood+1.580.010

Search GEO for disease gene expression data for Renal Cell Carcinoma.

Compounds for genes affiliated with Renal Cell Carcinoma

About this section
45Novoseek, 26HMDB
See all sources

Compounds related to Renal Cell Carcinoma according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1nnmt4510.7HNF1A, HNF1B
2glucose4510.7HNF1A, HNF1B, CA9, VHL, MET, MME
3proline4510.7TFE3, MET, VHL, CA9, HNF1A
4pyrimidine45 2611.6HNF1A, OGG1, NONO
5rapamycin4510.6CA9, VHL, MET, FLCN
6oligonucleotide4510.6MET, VHL, HNF1B, HNF1A, OGG1
7adriamycin4510.5OGG1, MET, MME
8crcs4510.5MET, MME
9thymidine45 2611.5MME, MET, HNF1A, OGG1
10oxygen45 2611.3MME, MET, VHL, CA9, OGG1
11estrogen4510.1HNF1A, CA9, VHL, MET, MME

GO Terms for genes affiliated with Renal Cell Carcinoma

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Cellular components related to Renal Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleusGO:000563410.4KANK1, FLCN, FAM107A, ASPSCR1, PRCC, VHL
2nucleolusGO:000573010.1NONO, TFE3, PRCC, VHL, CA9, HNF1B

Biological processes related to Renal Cell Carcinoma according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1regulation of pronephros sizeGO:003556510.7HNF1A, HNF1B
2positive regulation of transcription initiation from RNA polymerase II promoterGO:006026110.7HNF1A, HNF1B
3glucose homeostasisGO:004259310.6ASPSCR1, MET, HNF1A
4negative regulation of Rho protein signal transductionGO:003502410.6FLCN, KANK1
5positive regulation of transcription from RNA polymerase II promoterGO:004594410.6TFE3, FLCN, MET, HNF1B, HNF1A
6regulation of transcription from RNA polymerase II promoter in response to hypoxiaGO:006141810.5CA9, VHL
7branching morphogenesis of an epithelial tubeGO:004875410.5HNF1B, MET
8positive regulation of cell adhesionGO:004578510.5FLCN, TFE3
9insulin secretionGO:003007310.4HNF1B, HNF1A
10placenta developmentGO:000189010.2MET, PBRM1

Molecular functions related to Renal Cell Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription regulatory region DNA bindingGO:004421210.5HNF1A, HNF1B, TFE3
2protein bindingGO:000551510.1NONO, KANK1, FLCN, RNF139, MME, ASPSCR1

Products for genes affiliated with Renal Cell Carcinoma

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  • Antibodies
  • Proteins
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Sources for Renal Cell Carcinoma

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28ICD10 via Orphanet
36MESH via Orphanet
48OMIM via Orphanet
58SNOMED-CT via Orphanet
63UMLS via Orphanet