MCID: RNL024
MIFTS: 51

Renal Glucosuria malady

Categories: Genetic diseases, Rare diseases, Nephrological diseases, Metabolic diseases

Aliases & Classifications for Renal Glucosuria

About this section

Aliases & Descriptions for Renal Glucosuria:

Name: Renal Glucosuria 50 46 23 52 68 12 33
Renal Glycosuria 33 11 46 13
Familial Renal Glucosuria 52 25 66
Glycosuria, Renal 37 66
Glys1 23 68
 
Glucosuria, Renal 68
Sglt2 Deficiency 52
Renal Diabetes 11
Diabetes Renal 48
Glys 68

Characteristics:

Orphanet epidemiological data:

52
renal glucosuria:
Inheritance: Autosomal dominant,Autosomal recessive; Age of onset: All ages

HPO:

62
renal glucosuria:
Inheritance: autosomal dominant inheritance, autosomal recessive inheritance
Onset and clinical course: variable expressivity


Classifications:



External Ids:

OMIM50 233100
Disease Ontology11 DOID:9432
ICD1028 E74.8
ICD9CM30 271.4
MeSH37 D006030
Orphanet52 ORPHA69076
ICD10 via Orphanet29 E74.8
MedGen35 C0017980

Summaries for Renal Glucosuria

About this section
NIH Rare Diseases:46 Renal glycosuria is a rare condition in which glucose is excreted in the urine despite normal or low blood glucose levels. with normal kidney function, glucose is excreted in the urine only when there are abnormally elevated levels of glucose in the blood. however, in people with renal glycosuria, glucose is abnormally eliminated in the urine due to improper functioning of the renal tubules, which are the primary components of the filtering units of the kidneys. in most people with renal glycosuria, there are no apparent symptoms or serious effects. rare cases of polyuria (increased urine output), enuresis (involuntary urination), and mild growth and pubertal maturational delay have been reported. when renal glycosuria occurs as an isolated finding with otherwise normal kidney function, the condition is thought to be inherited in an autosomal recessive manner, caused by mutations in the  slc5a2 gene. treatment is not typically needed. last updated: 1/20/2016

MalaCards based summary: Renal Glucosuria, also known as renal glycosuria, is related to cataract, juvenile, with microcornea and glucosuria and renal cysts and diabetes syndrome, and has symptoms including polyuria, polydipsia and polyphagia. An important gene associated with Renal Glucosuria is SLC5A2 (Solute Carrier Family 5 Member 2), and among its related pathways are Carbohydrate digestion and absorption and Bile secretion. Affiliated tissues include kidney and bone, and related mouse phenotypes are behavior/neurological and growth/size/body region.

UniProtKB/Swiss-Prot:68 Renal glucosuria: A disorder characterized by persistent isolated glucosuria, normal fasting serum glucose concentration, decreased renal tubular resorption of glucose from the urine, and absence of any other signs of tubular dysfunction.

OMIM:50 Patients with familial renal glucosuria have decreased renal tubular resorption of glucose form the urine in the... (233100) more...

Wikipedia:69 Renal glycosuria, also known as renal glucosuria, is a rare condition in which the simple sugar glucose... more...

Related Diseases for Renal Glucosuria

About this section

Diseases related to Renal Glucosuria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 87)
idRelated DiseaseScoreTop Affiliating Genes
1cataract, juvenile, with microcornea and glucosuria11.4
2renal cysts and diabetes syndrome10.9
3neuroblastoma10.4
4endometriosis10.1
5pyelonephritis10.1
6thalassemia10.0
7aminoaciduria10.0
8osteogenesis imperfecta10.0
9endotheliitis9.9
10neural tube defects9.9
11hepatitis c virus9.9
12hereditary spastic paraplegia9.9
13glucose/galactose malabsorption9.9
14cataract9.9
15neuronitis9.9
16survival motor neuron spinal muscular atrophy9.8SLC2A2, SLC5A2
17osteoporosis9.8
18acute insulin response9.8
19polyneuropathy9.8
20melanoma9.8
21hemophilia9.8
22von willebrand disease9.8
23colorectal cancer9.6
24porphyria cutanea tarda9.6
25spondyloepimetaphyseal dysplasia9.6
26coronary artery disease9.6
27achondroplasia9.6
28osteogenesis imperfecta, type iv9.6
29cystic fibrosis9.6
30anorexia nervosa9.6
31meconium ileus9.6
32insulin-like growth factor i9.6
33pancreatic cancer9.6
34pseudoachondroplasia9.6
35prolidase deficiency9.6
36androgen insensitivity9.6
37hemophilia b9.6
38hemophilia a9.6
39lipoprotein lipase deficiency9.6
40hemolytic anemia9.6
41hepatitis9.6
42insulinoma9.6
43liver cirrhosis9.6
44motor neuron disease9.6
45artery disease9.6
46brain glioma9.6
47atrial fibrillation9.6
48stickler syndrome9.6
49myoglobinuria9.6
50microcytic anemia9.6

Comorbidity relations with Renal Glucosuria via Phenotypic Disease Network (PDN):


Chronic Kidney FailureHeart Disease

Graphical network of the top 20 diseases related to Renal Glucosuria:



Diseases related to renal glucosuria

Symptoms for Renal Glucosuria

About this section

Symptoms by clinical synopsis from OMIM:

233100

Clinical features from OMIM:

233100

HPO human phenotypes related to Renal Glucosuria:

id Description Frequency HPO Source Accession
1 polyuria HP:0000103
2 polydipsia HP:0001959
3 polyphagia HP:0002591
4 glycosuria HP:0003076
5 enuresis nocturna HP:0010677

Drugs & Therapeutics for Renal Glucosuria

About this section

Drugs for Renal Glucosuria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Insulin-glulisinePhase 4102207748-29-6
Synonyms:
 
Insulin Glulisine (recombinant DNA origin)
Insulin glulisine recombinant
2
Insulin GlarginePhase 4509160337-95-1
Synonyms:
 
Insulin Glargine (rDNA origin)
Insulin glargine recombinant
3
empagliflozinPhase 4107864070-44-0
Synonyms:
 
(1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol
1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy)benzyl)benzene
4potassium phosphatePhase 1, Phase 211
5
MetforminPhase 11701657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
6Trichostatin APhase 14858880-19-6
7
CanagliflozinPhase 1105842133-18-0
Synonyms:
 
Canagliflozin anhydrous
8
Uric acidPhase 112769-93-21175
Synonyms:
1H-Purine-2,6,8-triol
2,6,8-Trihydroxypurine
2,6,8-Trioxopurine
2,6,8-Trioxypurine
 
7,9-dihydro-1H-purine-2,6,8(3H)-trione
Lithate
Lithic acid
Purine-2,6,8(1H,3H,9H)-trione
Urate
Uric acid
9glucagonPhase 1441
10
Tenofovir709147127-20-6464205
Synonyms:
(R)-9-(2-Phosphonomethoxypropyl)adenine
(R)-9-(2-Phosphonylmethoxypropyl)adenine
(R)-9-(2-phosphonomethoxypropyl)adenine
(R)-PMPA
147127-20-6
206184-49-8
AC-760
AC1LA9BO
Anh. tenofovir
Anhydrous tenofovir
Apropovir
CHEBI:45809
CHEMBL483
CID464205
D,L-Tenofovir
DB00300
GNA & Tenofovir
GS 1275
GS 1278
GS1278
 
HHA & Tenofovir
KS-5021
MolPort-003-850-411
NCGC00167535-01
PMPA
PMPA-(R)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Galanthus nivalis agglutinin (GNA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Hippeastrum hybrid agglutinin( HHA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- (9CI)
Phosphonic acid, [[2-(6-amino-9H-purin-9
S1401_Selleck
TDF
TFV
Tenefovir
Tenofovir
Tenofovir (anh.)
Tenofovir disoproxil
Tenofovir disoproxil fumarate
UNII-99YXE507IL
Viread
Viread, Tenofovir
[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
11
Emtricitabine430143491-57-060877
Synonyms:
(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-.beta.-L-FTC
(-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
(-)-2'-Deoxy-5-fluoro-3'-thiacytidine
(-)-FTC
(-)-beta-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
(-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine
(-)-cis-4-amino-5-Fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
(-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
(2R-cis)-4-Amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
(2R-cis)-4-amino-5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
.beta.-L-(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
1-(2-(Hydroxymethyl)oxathiolan-5-yl)-5-fluorocytosine
143491-54-7
143491-57-0
145213-48-5
2',3',5-FTC
2',3'-Dideoxy-5-fluoro-3'-thiacytidine
2'-Deoxy-5-fluoro-3'-oxa-4'-thiocytidine
2'-Deoxy-5-fluoro-3'-thiacytidine
2-FTC
3'-Thia-2'.3'-dideoxy-5-fluorocytidine
4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one
4-Amino-5-fluoro-1-[(2R,5S)-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
4-amino-5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)[1,3]oxathiolan-5-yl]cytosine
524W91
AC1L1U3I
AC1Q4KUB
BW 1592
 
BW 524W91
BW-524W91
BW524W91
C122114
C12599
C8H10FN3O3S
CHEBI:31536
CHEMBL885
CID60877
Coviracil
Coviracil(TM)
D01199
DB00879
DRG-0208
Emtricitabin
Emtricitabina
Emtricitabine
Emtricitabine (JAN/USAN/INN)
Emtricitabinum
Emtriva
Emtriva (TN)
Emtriva(TM)
FT-0080009
HMS2089I05
HSDB 7337
LS-135838
LS-173184
NCGC00164564-01
RCV
Racivir
SBB066061
TL8000958
UNII-G70B4ETF4S
ZINC03629271
beta-L-2',3'-dideoxy-5-fluoro-3'-thiacytidine
dOTFC
emtricitabine
12insulin4401

Interventional clinical trials:

(show all 15)
idNameStatusNCT IDPhase
1Combined Diabetes-Renal Multifactorial Intervention In Patients With Advanced Diabetic Nephropathy (ADN)CompletedNCT00708981Phase 4
2SGLT-2 Inhibitor Empagliflozin Effects on Appetite and Weight Regulation.Not yet recruitingNCT02798744Phase 4
3Role Of Phosphorus And FGF 23 In Patients With Dent DiseaseRecruitingNCT02016235Phase 1, Phase 2
4A Study to Assess the Pharmacokinetics, Pharmacodynamics, and Safety of Canagliflozin (JNJ-28431754) in Volunteers With Varying Degrees of Kidney FunctionCompletedNCT01759576Phase 1
5A Comparison Of Study Drug Blood Levels After One Dose Of GSK189075 In Subjects With Normal And Reduced Kidney FunctionCompletedNCT00501462Phase 1
6Study to Assess the Pharmacokinetics, Pharmacodynamics, and Safety of Canagliflozin (JNJ-28431754) in Otherwise Healthy Obese VolunteersCompletedNCT01756404Phase 1
7The PK/PD Study of Multiple Dose of SHR3824 in Healthy VolunteersCompletedNCT02361138Phase 1
8A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of Canagliflozin in Older Children and Adolescents With Type 2 Diabetes MellitusCompletedNCT02000700Phase 1
9A First-in-Human Study of JNJ-28431754 in Healthy Male VolunteersCompletedNCT01177150Phase 1
10A Study to Assess the Pharmacokinetics and Pharmacodynamics of Canagliflozin in Healthy Chinese VolunteersCompletedNCT01707316Phase 1
11Genetics of Response to CanagliflozinNot yet recruitingNCT02891954Phase 1
12Renal, Endocrine, and Bone Changes in Response to FTC/TDF in Uninfected Young Men Who Have Sex With Men (YMSM).CompletedNCT01769469
13Study of Dapagliflozin on Mitochondrial Dysfunction and Impaired Insulin Signaling/ActionRecruitingNCT01439854
14Clinical Evaluation of Fenugreek Seed Extract, a Nutraceutical in Patients With Type- 2 DiabetesRecruitingNCT02693392
15Nervous System Degeneration in Glycosphingolipid Storage DisordersRecruitingNCT00029965

Search NIH Clinical Center for Renal Glucosuria


Cochrane evidence based reviews: glycosuria, renal

Genetic Tests for Renal Glucosuria

About this section

Genetic tests related to Renal Glucosuria:

id Genetic test Affiliating Genes
1 Familial Renal Glucosuria25
2 Renal Glucosuria23 SLC5A2

Anatomical Context for Renal Glucosuria

About this section

MalaCards organs/tissues related to Renal Glucosuria:

34
Kidney, Bone

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Renal Glucosuria:
id TissueAnatomical CompartmentCell Relevance
1 KidneyProximal TubuleProximal Tubule Cells Potential therapeutic candidate, affected by disease

Animal Models for Renal Glucosuria or affiliated genes

About this section

MGI Mouse Phenotypes related to Renal Glucosuria:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053867.6ATP6V0A4, SLC2A1, SLC2A2, SLC5A1, SLC5A2
2MP:00053787.3ATP6V0A4, SLC2A1, SLC2A2, SLC5A1, SLC5A2

Publications for Renal Glucosuria

About this section

Articles related to Renal Glucosuria:

(show all 23)
idTitleAuthorsYear
1
Novel SLC5A2 mutation contributes to familial renal glucosuria: Abnormal expression in renal tissues. (27446256)
2016
2
Determination of the renal threshold for glucose excretion in Familial Renal Glucosuria. (25896487)
2015
3
Novel SLC5A2 variants contribute to renal glucosuria in Chinese families: abnormal expression and dysfunction of variant SLC5A2. (25339128)
2015
4
A novel sodium-glucose co-transporter 2 gene (SGLT2) mutation contributes to the abnormal expression of SGLT2 in renal tissues in familial renal glucosuria. (24908283)
2014
5
Clinical and genetic analysis in a patient with primary renal glucosuria: Identification of a novel mutation in the SLC5A2 gene. (24255686)
2013
6
Hypouricaemia and hyperuricosuria in familial renal glucosuria. (26064518)
2013
7
Familial renal glucosuria: a clinicogenetic study of 23 additional cases. (22314875)
2012
8
Abnormal expression and dysfunction of novel SGLT2 mutations identified in familial renal glucosuria patients. (21165652)
2011
9
Familial renal glucosuria and SGLT2: from a mendelian trait to a therapeutic target. (19965550)
2010
10
Twenty-one additional cases of familial renal glucosuria: absence of genetic heterogeneity, high prevalence of private mutations and further evidence of volume depletion. (18622023)
2008
11
Mutation of solute carrier SLC16A12 associates with a syndrome combining juvenile cataract with microcornea and renal glucosuria. (18304496)
2008
12
Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting. (16518345)
2006
13
A novel missense mutation in SLC5A2 encoding SGLT2 underlies autosomal-recessive renal glucosuria and aminoaciduria. (15610225)
2005
14
Long-term outcome of renal glucosuria type 0: the original patient and his natural history. (15299100)
2004
15
Renal glucosuria due to SGLT2 mutations. (15110322)
2004
16
Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria. (14614622)
2004
17
Gene Symbol: SLC55A2. Disease: familial renal glucosuria. (15300967)
2004
18
A novel SGLT2 mutation in a patient with autosomal recessive renal glucosuria. (15496564)
2004
19
Molecular analysis of the SGLT2 gene in patients with renal glucosuria. (14569097)
2003
20
Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2). (12436245)
2002
21
Identification of a novel form of renal glucosuria with overexcretion of arginine, carnosine, and taurine. (11325687)
2001
22
Renal glucosuria and aminoaciduria. (899885)
1977
23
Glucose-galactose malabsorption. Studies on renal glucosuria. (5438804)
1970

Variations for Renal Glucosuria

About this section

UniProtKB/Swiss-Prot genetic disease variations for Renal Glucosuria:

68
id Symbol AA change Variation ID SNP ID
1SLC5A2p.Asn654SerVAR_019310rs61742739

Clinvar genetic disease variations for Renal Glucosuria:

5
id Gene Variation Type Significance SNP ID Assembly Location
1SLC5A2NM_003041.3(SLC5A2): c.1320G> A (p.Trp440Ter)single nucleotide variantPathogenicrs121918621GRCh37Chr 16, 31500240: 31500240
2NM_003041.3(SLC5A2): c.1961A> G (p.Asn654Ser)single nucleotide variantPathogenicrs61742739GRCh37Chr 16, 31501798: 31501798
3SLC5A2NM_003041.3(SLC5A2): c.500delA (p.Gln167Argfs)deletionPathogenicrs267607067GRCh37Chr 16, 31497522: 31497522
4SLC5A2SLC5A2, ALA89THRundetermined variantPathogenic
5SLC5A2NM_003041.3(SLC5A2): c.127-16C> Asingle nucleotide variantPathogenicrs398122801GRCh38Chr 16, 31484657: 31484657
6SLC5A2NM_003041.3(SLC5A2): c.294C> A (p.Phe98Leu)single nucleotide variantPathogenicrs398122802GRCh37Chr 16, 31496235: 31496235

Expression for genes affiliated with Renal Glucosuria

About this section
Search GEO for disease gene expression data for Renal Glucosuria.

Pathways for genes affiliated with Renal Glucosuria

About this section

Pathways related to Renal Glucosuria according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3SLC2A2, SLC5A1
29.1SLC2A1, SLC5A1
39.0SLC2A1, SLC2A2
49.0SLC2A1, SLC2A2
59.0SLC2A1, SLC2A2
68.7SLC2A1, SLC5A1, SLC5A2
7
Show member pathways
8.1SLC2A1, SLC2A2, SLC5A1, SLC5A2
8
Show member pathways
8.1SLC2A1, SLC2A2, SLC5A1, SLC5A2
9
Show member pathways
7.6ATP6V0A4, SLC2A1, SLC2A2, SLC5A1, SLC5A2
10
Show member pathways
7.6ATP6V0A4, SLC2A1, SLC2A2, SLC5A1, SLC5A2

GO Terms for genes affiliated with Renal Glucosuria

About this section

Cellular components related to Renal Glucosuria according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1brush borderGO:00059039.6ATP6V0A4, SLC2A2
2cell-cell junctionGO:00059118.7SLC2A1, SLC2A2, SLC5A1
3brush border membraneGO:00315268.4ATP6V0A4, SLC2A2, SLC5A1, SLC5A2
4apical plasma membraneGO:00163248.1ATP6V0A4, SLC2A1, SLC2A2, SLC5A1
5integral component of plasma membraneGO:00058877.3SLC16A12, SLC2A1, SLC2A2, SLC5A1, SLC5A2

Biological processes related to Renal Glucosuria according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1hexose transportGO:00086459.8SLC2A2, SLC5A1
2sodium ion transportGO:00068149.7SLC5A1, SLC5A2
3dehydroascorbic acid transportGO:00708379.5SLC2A1, SLC2A2
4carbohydrate metabolic processGO:00059759.4SLC2A2, SLC5A2
5regulation of insulin secretionGO:00507968.9SLC2A1, SLC2A2
6glucose transportGO:00157588.9SLC2A1, SLC2A2, SLC5A1
7glucose transmembrane transportGO:19046598.6SLC2A1, SLC2A2, SLC5A1, SLC5A2

Molecular functions related to Renal Glucosuria according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glucose:sodium symporter activityGO:00054129.7SLC5A1, SLC5A2
2dehydroascorbic acid transporter activityGO:00333009.0SLC2A1, SLC2A2
3D-glucose transmembrane transporter activityGO:00550568.9SLC2A1, SLC2A2
4glucose transmembrane transporter activityGO:00053558.7SLC2A1, SLC2A2

Sources for Renal Glucosuria

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet