MCID: RNL015
MIFTS: 48

Renal Hypertension malady

Categories: Cardiovascular diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Renal Hypertension

Aliases & Descriptions for Renal Hypertension:

Name: Renal Hypertension 12 14 69
Hypertension, Renal 42
Hypertension Renal 52

Classifications:



External Ids:

Disease Ontology 12 DOID:1073
MeSH 42 D006977
NCIt 47 C3121
SNOMED-CT 64 194775007 28119000
UMLS 69 C0020544

Summaries for Renal Hypertension

MalaCards based summary : Renal Hypertension, also known as hypertension, renal, is related to hyperuricemia, pulmonary hypertension, renal failure, and alkalosis and malignant hypertensive renal disease. An important gene associated with Renal Hypertension is EDN1 (Endothelin 1), and among its related pathways/superpathways are HIF-1-alpha transcription factor network and Renin secretion. The drugs Hydrochlorothiazide and Candesartan have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and brain, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Renal Hypertension

Diseases in the Renal Hypertension family:

Renal Failure, Progressive, with Hypertension

Diseases related to Renal Hypertension via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 133)
id Related Disease Score Top Affiliating Genes
1 hyperuricemia, pulmonary hypertension, renal failure, and alkalosis 33.3 ADM ALB NPPB
2 malignant hypertensive renal disease 12.0
3 benign hypertensive renal disease 11.9
4 renovascular hypertension 11.0
5 renal failure, progressive, with hypertension 10.8
6 polycystic kidney and hepatic disease 10.7
7 uterine inflammatory disease 10.3 EDN1 REN
8 transsexualism 10.3 ALB REN
9 antiphospholipid syndrome 10.3 ALB REN
10 adenocarcinoma 10.3 EDN1 REN
11 chronic inflammatory demyelinating polyneuropathy 10.3 NPPB REN
12 hypotrichosis simplex 10.2 ACE REN
13 hyperinsulinemic hypoglycemia, familial, 3 10.2 ACE REN
14 carbohydrate metabolic disorder 10.2 ACE REN
15 citrulline transport defect 10.2 EDN1 NPPB
16 hypothyroidism, congenital nongoitrous, 5 10.2 ACE REN
17 hypogonadism mitral valve prolapse mental retardation 10.2 ACE REN
18 indeterminate leprosy 10.2 EDN1 KNG1
19 listeriosis 10.2 ACE REN
20 capillary hemangioma 10.2 ALB EDN1 REN
21 dystonia 25 10.2 REN SLC12A3
22 hepatic infarction 10.2 EDN1 KNG1 REN
23 paranasal sinus sarcoma 10.2 ALB EDN1 REN
24 idiopathic peripheral autonomic neuropathy 10.2 ALB NPPB
25 ectodermal dysplasia 9, hair/nail type 10.2 EDN1 EPO NPPB
26 inferolateral myocardial infarct 10.2 ACE NPPB
27 glucosephosphate dehydrogenase deficiency 10.2 ALB NPPB
28 spondyloarthropathy 2 10.1 ACE ALB
29 congenital nystagmus 10.1 ACE ALB REN
30 dientamoebiasis 10.1 ACE EPO REN
31 autonomic neuropathy 10.1 NPPB REN
32 shaken baby syndrome 10.1 DBH REN
33 limb ischemia 10.1 ACE EDN1 REN
34 schizotypal personality disorder 10.1 ACE ALB REN
35 anogenital venereal wart 10.1 ACE ALB EDN1
36 viral hepatitis 10.1 ACE EDN1 KNG1
37 peroneal neuropathy 10.1 ACE ALB REN
38 fiedler's myocarditis 10.1 AGTR1 ALB EDN1
39 aorta angiosarcoma 10.1 ACE REN SLC12A3
40 body dysmorphic disorder 10.1 ACE ALB REN
41 syringomelia hyperkeratosis 10.1 ACE ALB NPPB
42 deafness, autosomal recessive 79 10.1 ACE NPPB REN
43 secretory diarrhea myopathy and deafness 10.1 ACE KNG1
44 ceroid lipofuscinosis, neuronal, kufs type, adult onset 10.1 ACE NPPB REN
45 adult t-cell leukemia 10.1 ACE EDN1 NPPB
46 iris disease 10.1 ACE AGTR1 REN
47 aplasia cutis congenita recessive 10.1 ACE AGTR1 EDN1
48 cascade stomach 10.1 ACE AGTR1 REN
49 hyperuricemic nephropathy, familial juvenile 2 10.1 ACE AGTR1 REN
50 alpha-2-plasmin inhibitor deficiency 10.1 ACE AGTR1 EDN1

Graphical network of the top 20 diseases related to Renal Hypertension:



Diseases related to Renal Hypertension

Symptoms & Phenotypes for Renal Hypertension

MGI Mouse Phenotypes related to Renal Hypertension:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.81 ACE ADM AGTR1 DBH EDN1 EPO
2 homeostasis/metabolism MP:0005376 9.65 SLC12A3 ACE ADM AGTR1 ALB DBH
3 renal/urinary system MP:0005367 9.17 ACE ADM AGTR1 ALB EDN1 REN

Drugs & Therapeutics for Renal Hypertension

Drugs for Renal Hypertension (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 651)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-93-5 3639
2
Candesartan Approved Phase 4,Phase 3,Phase 2 139481-59-7 2541
3
Cilnidipine Approved Phase 4,Phase 2 132203-70-4 5282138
4
Aspirin Approved, Vet_approved Phase 4,Phase 2 50-78-2 2244
5
Ticlopidine Approved Phase 4 55142-85-3 5472
6
Digoxin Approved Phase 4 20830-75-5 30322 2724385
7
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
8
Amiloride Approved Phase 4,Phase 2,Phase 1 2016-88-8, 2609-46-3 16231
9
Amlodipine Approved Phase 4,Phase 3,Phase 1,Early Phase 1 88150-42-9 2162
10
Simvastatin Approved Phase 4,Phase 3 79902-63-9 54454
11
Telmisartan Approved, Investigational Phase 4,Phase 3,Phase 2 144701-48-4 65999
12
Lisinopril Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 83915-83-7 5362119
13
Atenolol Approved Phase 4,Phase 3,Early Phase 1 29122-68-7 2249
14
Clonidine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 4205-90-7 2803
15
Doxazosin Approved Phase 4 74191-85-8 3157
16
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 54-31-9 3440
17
Irbesartan Approved, Investigational Phase 4,Phase 3,Phase 2 138402-11-6 3749
18
Ramipril Approved Phase 4,Phase 3,Phase 2,Phase 1 87333-19-5 5362129
19
Eplerenone Approved Phase 4,Phase 3,Phase 1,Phase 2 107724-20-9 150310 443872
20
Spironolactone Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1952-01-7, 52-01-7 5833
21
Basiliximab Approved, Investigational Phase 4,Phase 3,Phase 2 152923-56-3, 179045-86-4
22
Benzocaine Approved Phase 4,Phase 3,Phase 2 1994-09-7, 94-09-7 2337
23
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 79217-60-0, 59865-13-3 5284373 6435893
24
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
25
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
26
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
27
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
28
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
29
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
30
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
31 Moxonidine Approved Phase 4 75438-57-2 4810
32
Fluvastatin Approved Phase 4,Phase 3,Phase 2 93957-54-1 1548972
33
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137862-53-4 60846
34
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
35
Losartan Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 114798-26-4 3961
36
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
37
Pancrelipase Approved Phase 4 53608-75-6
38
Enalapril Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 75847-73-3 5362032 40466924
39
Enalaprilat Approved Phase 4,Phase 2,Phase 3,Phase 1 76420-72-9 6917719
40
Hydralazine Approved Phase 4,Phase 2,Phase 3,Early Phase 1 86-54-4 3637
41
Nitrofurantoin Approved, Vet_approved Phase 4,Phase 3 67-20-9 5353830
42
Trimethoprim Approved, Vet_approved Phase 4,Phase 3,Phase 2 738-70-5 5578
43
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1 10102-43-9 145068
44
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1 657-24-9 14219 4091
45
Pioglitazone Approved, Investigational Phase 4,Phase 3 111025-46-8 4829
46
Olmesartan Approved, Investigational Phase 4,Phase 3 144689-24-7, 144689-63-4 158781 130881
47
Menthol Approved Phase 4,Phase 3,Phase 2 2216-51-5 16666
48
Fenofibrate Approved Phase 4,Phase 3 49562-28-9 3339
49
Sevelamer Approved Phase 4,Phase 3,Phase 2 52757-95-6, 152751-57-0 3085017
50
Liraglutide Approved Phase 4 204656-20-2

Interventional clinical trials:

(show top 50) (show all 1276)
id Name Status NCT ID Phase
1 Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy Unknown status NCT01023373 Phase 4
2 Effect of Aliskiren and Hydrochlorothiazide on Kidney Oxygenation in Patients With Hypertension Unknown status NCT01519635 Phase 4
3 CCB Safety Study in Treatment of Hypertension of ADPKD Unknown status NCT00541853 Phase 4
4 Medical and Endovascular Treatment of Atherosclerotic Renal Artery Stenosis (METRAS Study) Unknown status NCT01208714 Phase 4
5 Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal Disease Unknown status NCT00852787 Phase 4
6 Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease Unknown status NCT01155128 Phase 4
7 Comparison of Stenting Versus Best Medical Therapy for Treatment of Ostial Renal Artery Stenosis: a Trial in Patients With Advanced Atherosclerosis Unknown status NCT00711984 Phase 4
8 A Study Comparing Outcomes of Kidney Transplants in Patients on Steroids Versus Those Who Discontinue Steroids Unknown status NCT00273559 Phase 4
9 Aliskiren and Muscle Sympathetic Nerve Activity Unknown status NCT00719316 Phase 4
10 Investigator Initiated Randomized Open-label Comparative Study of Britomar (Prolonged Release Torasemide) and Diuver (Torasemide) to Assess Effects on Natriuresis and Central Hemodynamics. Unknown status NCT02087332 Phase 4
11 A Prospective Study of the Kidney Protective Effect of Aliskiren in Hypertensive Patients With IgA Nephropathy Unknown status NCT01184599 Phase 4
12 Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients Unknown status NCT01011660 Phase 4
13 Dose Titration of Lisinopril in Children Aged 1 to 18 Years With Primary or Secondary Hypertension Unknown status NCT02184858 Phase 4
14 The INDORSE Study: Inhibition of Dipeptidyl Peptidase IV: Outcomes on Renal Sodium Excretion Unknown status NCT02406443 Phase 4
15 Vitamin K2 and Vessel Calcification in Chronic Kidney Disease Patients Unknown status NCT01101698 Phase 4
16 Nephropathy In Type 2 Diabetes and Cardio-renal Events Unknown status NCT00535925 Phase 4
17 Does Aldosterone Cause Hypertension by a Non-Renal Mechanism? Unknown status NCT00553722 Phase 4
18 Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation Unknown status NCT00903188 Phase 4
19 The Effect of Moxonidine on Blood Pressure and Regression of Early Target Organ Damage in Young Subjects With Abdominal Obesity and Hypertension Unknown status NCT01360710 Phase 4
20 Effects of Spironolactone in Dialysis Unknown status NCT01128101 Phase 4
21 RAAS Inhibitor Drugs in Dialysis Patients Unknown status NCT01635387 Phase 4
22 Acthar as Rescue Therapy for Transplant Glomerulopathy in Kidney Transplant Recipients Unknown status NCT02057523 Phase 4
23 Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathy Unknown status NCT01673204 Phase 4
24 Diabetes Type 1, Treatment Study Atacand/Placebo After Kidney Biopsy Unknown status NCT00328302 Phase 4
25 Intensive Medical Treatment for Nephropathy Caused by Type 2 Diabetes With Hypertension Unknown status NCT00407680 Phase 4
26 Reduction or Discontinuation of CNI's With Conversion to Everolimus-Based Immunosuppresion Unknown status NCT00443508 Phase 4
27 Hemocontrol's Effectiveness on the Reduction of Cardiovascular Long-term EventS Unknown status NCT01515878 Phase 4
28 Study of the Effect of Moxonidine and Diet on Sympathetic Functions in Young Adults With Obesity Unknown status NCT01180231 Phase 4
29 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4
30 Hypertension Control Based on Home Blood Pressure Unknown status NCT00198562 Phase 4
31 Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin. Unknown status NCT00404599 Phase 4
32 More Frequent Dialysis (>3 Treatments Per Week) Unknown status NCT00575497 Phase 4
33 Effects of the Use of "de Novo" Everolimus in Renal Tranplant Population Unknown status NCT01663805 Phase 4
34 A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus Corticosteroids Unknown status NCT00693446 Phase 4
35 The Effect of Enalapril and Losartan on Peritoneal Membrane in Continuous Ambulatory Peritoneal Dialysis Patients Unknown status NCT01041963 Phase 4
36 ACEIs and ARBs Treatment in Diabetic Patients -Drug Interactions and Adverse Drug Effects Unknown status NCT00437775 Phase 4
37 Effects of Antibiotic Prophylaxis on Recurrent UTI in Children Unknown status NCT02357758 Phase 4
38 The ACT-OUT Trial: ACTivity OUTcomes Based on High Carbohydrate or High Fat Diet in Metabolic Syndrome Unknown status NCT01357382 Phase 4
39 Major Depressive Disorder - Understanding The Link Between The Brain And The Heart Unknown status NCT01568307 Phase 4
40 Mycophenolate Mofetil in Pediatric Steroid Dependent Nephrotic Syndrome Unknown status NCT01895894 Phase 4
41 Low Dose Steroids in the Treatment of Nephrotic Syndrome Relapse Unknown status NCT02216747 Phase 4
42 Renal Response to Lower Body Negative Pressure in Pre-hypertensive States Completed NCT01734096 Phase 4
43 Renal Sympathetic Denervation in Mild Refractory Hypertension Completed NCT01656096 Phase 4
44 Indapamide Versus Hydrochlorothiazide in Elderly Hypertensive Patients With Renal Insufficiency Completed NCT01172431 Phase 4
45 Renal and Systemic Vascular Resistance in Chronic Kidney Disease (CKD) Completed NCT01380717 Phase 4
46 A Study to Describe Vascular and Renal Effects and Safety of Valsartan in Patients With High Blood Pressure Completed NCT00171353 Phase 4
47 Effects of Aliskiren in Elderly Hypertensive Chronic Kidney Disease (CKD) Patients Completed NCT01284114 Phase 4
48 Nebivolol Effect on Nitric Oxide Levels, Blood Pressure, and Renal Function in Kidney Transplant Patients Completed NCT01157234 Phase 4
49 Zainidip in Renal Artery Stenosis Completed NCT02594410 Phase 4
50 The Effect of Eprosartan on Hormones and Kidney Function in Patients With Essential Hypertension Completed NCT00438945 Phase 4

Search NIH Clinical Center for Renal Hypertension

Cochrane evidence based reviews: hypertension, renal

Genetic Tests for Renal Hypertension

Anatomical Context for Renal Hypertension

MalaCards organs/tissues related to Renal Hypertension:

39
Kidney, Heart, Brain, Testes, Endothelial, Smooth Muscle, Cortex

Publications for Renal Hypertension

Articles related to Renal Hypertension:

(show top 50) (show all 511)
id Title Authors Year
1
Flax lignan concentrate reverses alterations in blood pressure, left ventricular functions, lipid profile and antioxidant status in DOCA-salt induced renal hypertension in rats. ( 26795298 )
2016
2
Hydroalcoholic extract of Allium eriophyllum leaves attenuates cardiac impairment in rats with simultaneous type 2 diabetes and renal hypertension. ( 26487889 )
2015
3
The effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension: a study of antihypertensive mechanisms. ( 25821295 )
2015
4
The cardioprotective effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension. ( 25920277 )
2015
5
Renal hypertension and cardiovascular disorder in children with chronic kidney disease. ( 24684043 )
2014
6
Effects of oleuropein in rats with simultaneous type 2 diabetes and renal hypertension: a study of antihypertensive mechanisms. ( 24954237 )
2014
7
Curable renal hypertension: renin, marker or cause? Question answered. ( 25103928 )
2014
8
Oleuropein offers cardioprotection in rats with simultaneous type 2 diabetes and renal hypertension. ( 25097277 )
2014
9
Editorial (thematic issue: all roads of renal hypertension lead to or come from CKD). ( 25549836 )
2014
10
Renal denervation for resistant hypertension using an irrigated radiofrequency balloon: 12-month results from the Renal Hypertension Ablation System (RHAS) trial. ( 23685297 )
2013
11
Renal hypertension: an unusual cause for a common problem. ( 23371394 )
2013
12
Simultaneous renal hypertension and type 2 diabetes exacerbate vascular endothelial dysfunction in rats. ( 22458508 )
2012
13
ESPR uroradiology task force and ESUR paediatric working group: imaging recommendations in paediatric uroradiology, part IV: Minutes of the ESPR uroradiology task force mini-symposium on imaging in childhood renal hypertension and imaging of renal trauma in children. ( 21710387 )
2011
14
Effect of age and sex on blood pressure, development of renal hypertension, and concentration of nitric oxide in the blood of albino rats. ( 21113443 )
2010
15
Comprehensive evaluation of patients with suspected renal hypertension using MDCT: from protocol to interpretation. ( 19380531 )
2009
16
Effectiveness of unilateral nephrectomy for renal hypertension in adults. ( 19010760 )
2008
17
Cardiovascular reactivity of patients with essential and renal hypertension in an emotion-triggering interview. ( 17348427 )
2007
18
Total peripheral resistance responsiveness during the development of secondary renal hypertension in dogs. ( 17278982 )
2007
19
Renal capsular PEComa--a rare cause of surgically correctable renal hypertension. ( 17318350 )
2007
20
Cardiovascular reactivity in patients with essential or renal hypertension under standardized mental stress. ( 17653965 )
2007
21
Correction of renal hypertension after kidney transplantation from a donor with Gitelman syndrome. ( 16479187 )
2006
22
Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child. ( 15711357 )
2005
23
Ventricular structure and function in aged dogs with renal hypertension: a model of experimental diastolic heart failure. ( 15723971 )
2005
24
Water intake during the development of renal hypertension (2K-1C) in mice. ( 15992836 )
2005
25
Cardiovascular hypertrophy in one-kidney, one-clip renal hypertension is resistant to heparin. ( 15126919 )
2004
26
Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child. ( 14678186 )
2004
27
[Clinical observation of the therapeutic effect of valsartan for renal hypertension in 64 cases]. ( 13129740 )
2003
28
Mild renal hypertension alters run training effects on the frequency response of rat cardiomyocyte mechanics. ( 12857770 )
2003
29
The role of partial nephrectomy in the treatment of pediatric renal hypertension. ( 12544329 )
2003
30
Sympathetic nervous system function in renal hypertension. ( 12003706 )
2002
31
Mouse model of cerebral aneurysm: experimental induction by renal hypertension and local hemodynamic changes. ( 12105374 )
2002
32
Factors influencing acute ischaemia-induced renal hypertension in rats. ( 12473871 )
2002
33
Neurohormonal influences on maintenance and reversal of two-kidney one-clip renal hypertension. ( 12100364 )
2002
34
Role of angiotensin II and free radicals in blood pressure regulation in a rat model of renal hypertension. ( 11566905 )
2001
35
Altered contractions to endothelin-1, phenylephrine, potassium chloride and relaxations to acetylcholine at various stages of renal hypertension in the rat. ( 11401413 )
2001
36
Renal hypertension prevents run training modification of cardiomyocyte diastolic Ca2+ regulation in male rats. ( 11356766 )
2001
37
[The protection of renal function in the ACEI treatment of renal hypertension]. ( 12206011 )
2000
38
Plasma-levels of endothelin-1 and angiotensin-II and reactivity of arterial blood pressure to exogenous sympathomimetics and vasoactive peptides in rat model of malignant renal hypertension. ( 10870254 )
2000
39
Effects of YM358, an angiotensin II type 1 (AT1) receptor antagonist, and enalapril on blood pressure and vasoconstriction in two renal hypertension models. ( 10706380 )
2000
40
Plasma brain natriuretic peptides and renal hypertension. ( 10955934 )
2000
41
Effect of ramipril on ambulatory blood pressure and albuminuria in renal hypertension. ( 11095026 )
2000
42
Poland's syndrome--complicated with renal hypertension. ( 11273191 )
2000
43
Acute AT1 receptor blockade does not improve the depressed baroreflex in rats with chronic renal hypertension. ( 11105103 )
2000
44
AT(1) receptor inhibition does not reduce arterial wall hypertrophy or PDGF-A expression in renal hypertension. ( 10666094 )
2000
45
Decreased diurnal blood pressure variability and low dehydroepiandrosterone sulfate levels in patients with renal hypertension, and after kidney transplantation. ( 10463206 )
1999
46
How reproducible is diurnal blood pressure rhythm in patients with secondary (renal) hypertension? ( 10756891 )
1999
47
[Study on the relationship between plasma endothelin nitric oxide concentration and renal hypertension and renal function]. ( 12080656 )
1999
48
Serial magnetic resonance imaging of rat brain after induction of renal hypertension. ( 10548682 )
1999
49
Renal hypertension due to giant perirenal haematoma: permanent resolution by percutaneous ultrasound-guided drainage. ( 9561580 )
1998
50
Antagonism of ANG II type 1 receptors protects the endothelium during the early stages of renal hypertension in rats. ( 9843884 )
1998

Variations for Renal Hypertension

Expression for Renal Hypertension

Search GEO for disease gene expression data for Renal Hypertension.

Pathways for Renal Hypertension

Pathways related to Renal Hypertension according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.14 ADM EDN1 EPO
2 10.94 ACE AGTR1 REN
3
Show member pathways
10.83 ACE AGTR1 KNG1 REN
4 10.62 ADM DBH

GO Terms for Renal Hypertension

Cellular components related to Renal Hypertension according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 ACE ADM ALB DBH EDN1 EPO
2 extracellular space GO:0005615 9.32 ACE ADM ALB DBH EDN1 EPO

Biological processes related to Renal Hypertension according to GeneCards Suite gene sharing:

(show all 23)
id Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 9.77 ADM EDN1 EPO
2 response to lipopolysaccharide GO:0032496 9.73 ADM EDN1 EPO REN
3 kidney development GO:0001822 9.7 ACE AGTR1 REN
4 positive regulation of cytosolic calcium ion concentration GO:0007204 9.67 ADM AGTR1 EDN1 KNG1
5 response to testosterone GO:0033574 9.61 EDN1 EPO
6 blood vessel remodeling GO:0001974 9.61 ACE DBH
7 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway GO:0051482 9.6 AGTR1 EDN1
8 positive regulation of heart rate GO:0010460 9.58 ADM EDN1
9 blood coagulation, intrinsic pathway GO:0007597 9.58 KLKB1 KNG1
10 beta-amyloid metabolic process GO:0050435 9.57 ACE REN
11 positive regulation of urine volume GO:0035810 9.56 EDN1 NPPB
12 positive regulation of renal sodium excretion GO:0035815 9.55 EDN1 NPPB
13 negative regulation of blood coagulation GO:0030195 9.54 EDN1 KNG1
14 angiotensin maturation GO:0002003 9.51 ACE REN
15 regulation of vasoconstriction GO:0019229 9.5 ACE AGTR1 EDN1
16 response to dexamethasone GO:0071548 9.49 EDN1 EPO
17 body fluid secretion GO:0007589 9.48 EDN1 NPPB
18 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.46 ACE AGTR1
19 regulation of blood vessel size GO:0050880 9.43 EDN1 KNG1 NPPB
20 renin-angiotensin regulation of aldosterone production GO:0002018 9.4 AGTR1 REN
21 regulation of vasodilation GO:0042312 9.33 ACE AGTR1 NPPB
22 regulation of blood pressure GO:0008217 9.26 ACE EDN1 NPPB REN
23 regulation of blood vessel diameter GO:0097746 8.8 ACE AGTR1 NPPB

Molecular functions related to Renal Hypertension according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.55 ADM EDN1 KNG1 NPPB REN
2 bradykinin receptor binding GO:0031711 8.96 ACE AGTR1
3 hormone activity GO:0005179 8.92 ADM EDN1 EPO NPPB

Sources for Renal Hypertension

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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