MCID: RNL015
MIFTS: 47

Renal Hypertension

Categories: Cardiovascular diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Renal Hypertension

MalaCards integrated aliases for Renal Hypertension:

Name: Renal Hypertension 12 14 69
Hypertension, Renal 42
Hypertension Renal 52

Classifications:



External Ids:

Disease Ontology 12 DOID:1073
MeSH 42 D006977
NCIt 47 C3121
SNOMED-CT 64 194775007 28119000
UMLS 69 C0020544

Summaries for Renal Hypertension

MalaCards based summary : Renal Hypertension, also known as hypertension, renal, is related to hyperuricemia, pulmonary hypertension, renal failure, and alkalosis and malignant hypertensive renal disease. An important gene associated with Renal Hypertension is EDN1 (Endothelin 1), and among its related pathways/superpathways are HIF-1-alpha transcription factor network and Renin secretion. The drugs Hydrochlorothiazide and Adenosine have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and endothelial, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Renal Hypertension

Diseases in the Renal Hypertension family:

Renal Failure, Progressive, with Hypertension

Diseases related to Renal Hypertension via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 165)
id Related Disease Score Top Affiliating Genes
1 hyperuricemia, pulmonary hypertension, renal failure, and alkalosis 12.2
2 malignant hypertensive renal disease 12.0
3 benign hypertensive renal disease 11.9
4 renovascular hypertension 11.0
5 renal failure, progressive, with hypertension 10.8
6 ciliary discoordination, due to random ciliary orientation 10.7 EDN1 NPPB
7 uterine inflammatory disease 10.7 EDN1 REN
8 idiopathic peripheral autonomic neuropathy 10.7 ALB NPPB
9 polycystic kidney disease 4, with or without hepatic disease 10.7
10 polycystic kidney disease 3 10.7
11 chronic inflammatory demyelinating polyneuritis 10.7 ALB EPO
12 wernicke-korsakoff syndrome 10.7 ALB REN
13 antiphospholipid syndrome 10.7 EDN1 REN
14 iga glomerulonephritis 10.7 ALB REN
15 congenital nonspherocytic hemolytic anemia 10.7 ALB NPPB
16 chronic granulomatous disease 10.7 NPPB REN
17 cerebral sarcoidosis 10.6 ALB EPO
18 testicular germ cell tumor non-seminomatous 10.6 ALB NPPB
19 conjunctival vascular disease 10.6 ALB EPO
20 cervical mullerian papilloma 10.6 ACE EPO
21 childhood brain stem glioma 10.6 ALB EPO
22 retinitis pigmentosa 70 10.6 ACE ALB
23 marden-walker syndrome 10.6 REN SLC12A3
24 hypothyroidism due to iodide transport defect 10.6 ACE REN
25 eustachian tube disease 10.6 EDN1 REN
26 articulation disorder 10.6 ALB EPO
27 autonomic neuropathy 10.6 NPPB REN
28 primary hyperoxaluria 10.5 ACE REN
29 atrial septal defect 7, with or without av conduction defects 10.5 ACE REN
30 mody, type ii 10.5 ACE REN
31 hypodontia of incisors and premolars 10.5 ACE REN
32 microcephaly 8, primary, autosomal recessive 10.5 ALB EPO
33 listeriosis 10.5 ACE REN
34 dementia pugilistica 10.5 ADM NPPB
35 indeterminate leprosy 10.5 EDN1 KNG1
36 lethal congenital contractural syndrome 2 10.5 EDN1 EPO NPPB
37 rheumatic fever 10.5 EDN1 KNG1
38 pleomorphic liposarcoma 10.5 ACE NPPB
39 munchausen by proxy 10.5 ACE EDN1
40 islet cell tumor 10.5 ACE NPPB
41 capillary hemangioma 10.4 ALB EDN1 REN
42 placental abruption 10.4 ACE NPPB
43 paranasal sinus sarcoma 10.4 ALB EDN1 REN
44 pes anserinus tendinitis or bursitis 10.4 ALB EPO
45 cystic fibrosis and congenital absence of the vas deferens 10.4 AGTR1 REN
46 female breast upper-outer quadrant cancer 10.4 AGTR1 EDN1
47 suppurative otitis media 10.4 ACE NPPB
48 synovial chondromatosis 10.4 ACE ALB NPPB
49 anogenital venereal wart 10.4 ACE ALB EDN1
50 rhinitis 10.4 REN SLC12A3

Graphical network of the top 20 diseases related to Renal Hypertension:



Diseases related to Renal Hypertension

Symptoms & Phenotypes for Renal Hypertension

MGI Mouse Phenotypes related to Renal Hypertension:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.81 ACE ADM AGTR1 DBH EDN1 EPO
2 homeostasis/metabolism MP:0005376 9.65 ALB DBH EDN1 EPO KLKB1 REN
3 renal/urinary system MP:0005367 9.17 ACE ADM AGTR1 ALB EDN1 REN

Drugs & Therapeutics for Renal Hypertension

Drugs for Renal Hypertension (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 560)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-93-5 3639
2
Adenosine Approved, Investigational Phase 4 58-61-7 60961
3
Candesartan Approved Phase 4,Phase 3,Phase 2 139481-59-7 2541
4
Cilnidipine Approved Phase 4,Phase 2 132203-70-4 5282138
5
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
6
Ticlopidine Approved Phase 4 55142-85-3 5472
7
Digoxin Approved Phase 4 20830-75-5 30322 2724385
8
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 1 53-03-2 5865
9
Amiloride Approved Phase 4,Phase 2,Phase 1 2016-88-8, 2609-46-3 16231
10
Amlodipine Approved Phase 4,Phase 3,Phase 1,Early Phase 1 88150-42-9 2162
11
Simvastatin Approved Phase 4,Phase 3 79902-63-9 54454
12
Telmisartan Approved, Investigational Phase 4,Phase 3,Phase 2 144701-48-4 65999
13
Lisinopril Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 83915-83-7, 76547-98-3 5362119
14
Atenolol Approved Phase 4,Phase 3,Early Phase 1 29122-68-7 2249
15
Clonidine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 4205-90-7 2803
16
Doxazosin Approved Phase 4 74191-85-8 3157
17
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 54-31-9 3440
18
Irbesartan Approved, Investigational Phase 4,Phase 3,Phase 2 138402-11-6 3749
19
Ramipril Approved Phase 4,Phase 3,Phase 2,Phase 1 87333-19-5 5362129
20
Eplerenone Approved Phase 4,Phase 3,Phase 1,Phase 2 107724-20-9 150310 443872
21
Spironolactone Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1952-01-7, 52-01-7 5833
22
Basiliximab Approved, Investigational Phase 4,Phase 3,Phase 2 152923-56-3, 179045-86-4
23
Benzocaine Approved Phase 4,Phase 3,Phase 2 1994-09-7, 94-09-7 2337
24
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
25
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
26
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
27
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
28
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
29
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
30
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
31
Moxonidine Approved Phase 4 75438-57-2 4810
32
Fluvastatin Approved Phase 4,Phase 3,Phase 2 93957-54-1 1548972
33
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137862-53-4 60846
34
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
35
Losartan Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 114798-26-4 3961
36
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
37
Pancrelipase Approved Phase 4 53608-75-6
38
Enalapril Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 75847-73-3 5362032 40466924
39
Enalaprilat Approved Phase 4,Phase 2,Phase 3,Phase 1 76420-72-9 6917719
40
Hydralazine Approved Phase 4,Phase 2,Phase 3,Early Phase 1 86-54-4 3637
41
Nitrofurantoin Approved, Vet_approved Phase 4,Phase 3 67-20-9 5353830
42
Trimethoprim Approved, Vet_approved Phase 4,Phase 3,Phase 2 738-70-5 5578
43
Metoprolol Approved, Investigational Phase 4,Phase 3,Phase 2 37350-58-6, 51384-51-1 4171
44
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1 10102-43-9 145068
45
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1 657-24-9 14219 4091
46
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
47
Olmesartan Approved, Investigational Phase 4,Phase 3 144689-24-7, 144689-63-4 158781 130881
48
Menthol Approved Phase 4,Phase 3,Phase 2 2216-51-5 16666
49
Fenofibrate Approved Phase 4 49562-28-9 3339
50
Nifedipine Approved Phase 4,Phase 2,Phase 1 21829-25-4 4485

Interventional clinical trials:

(show top 50) (show all 1083)

id Name Status NCT ID Phase Drugs
1 Effect of Aliskiren and Hydrochlorothiazide on Kidney Oxygenation in Patients With Hypertension Unknown status NCT01519635 Phase 4 Aliskiren;Hydrochlorothiazide
2 Effects of REnal Denervation for Resistant Hypertension on Exercise Diastolic Function and Regression of Atherosclerosis and the Evaluation of NEW Methods Predicting A successfuL Renal Sympathetic Denervation (RENEWAL-EXERCISE, -REGRESS, and -PREDICT Tria Unknown status NCT01918111 Phase 4 adenosine infusion treatment
3 CCB Safety Study in Treatment of Hypertension of ADPKD Unknown status NCT00541853 Phase 4 Candesartan;Candesartan and Cilnidipine;Candesartan plus non-CCB agents
4 Medical and Endovascular Treatment of Atherosclerotic Renal Artery Stenosis (METRAS Study) Unknown status NCT01208714 Phase 4 Optimal medical therapy
5 Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy Unknown status NCT01023373 Phase 4 Medical treatment
6 Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal Disease Unknown status NCT00852787 Phase 4 Digoxin immune fab;Placebo
7 Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease Unknown status NCT01155128 Phase 4
8 Comparison of Stenting Versus Best Medical Therapy for Treatment of Ostial Renal Artery Stenosis: a Trial in Patients With Advanced Atherosclerosis Unknown status NCT00711984 Phase 4
9 A Study Comparing Outcomes of Kidney Transplants in Patients on Steroids Versus Those Who Discontinue Steroids Unknown status NCT00273559 Phase 4 prednisone
10 Aliskiren and Muscle Sympathetic Nerve Activity Unknown status NCT00719316 Phase 4 Aliskiren
11 Investigator Initiated Randomized Open-label Comparative Study of Britomar (Prolonged Release Torasemide) and Diuver (Torasemide) to Assess Effects on Natriuresis and Central Hemodynamics. Unknown status NCT02087332 Phase 4 Prolonged release Torasemide (Britomar);Torasemide (Diuver)
12 A Prospective Study of the Kidney Protective Effect of Aliskiren in Hypertensive Patients With IgA Nephropathy Unknown status NCT01184599 Phase 4 aliskiren
13 Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients Unknown status NCT01011660 Phase 4 Amlodipine, Telmisartan, Amiloride Compound , Simvastatin
14 Dose Titration of Lisinopril in Children Aged 1 to 18 Years With Primary or Secondary Hypertension Unknown status NCT02184858 Phase 4 lisinopril, ACE-inhibitor
15 The INDORSE Study: Inhibition of Dipeptidyl Peptidase IV: Outcomes on Renal Sodium Excretion Unknown status NCT02406443 Phase 4 Sitaglitpin
16 Vitamin K2 and Vessel Calcification in Chronic Kidney Disease Patients Unknown status NCT01101698 Phase 4 Vitamin K2+10μg cholecalciferol;Vitamin D
17 Nephropathy In Type 2 Diabetes and Cardio-renal Events Unknown status NCT00535925 Phase 4 current therapy;irbesartan;ramipril;hydrochlorothiazide;furosemide;amlodipine;atenolol;doxazosin;clonidine;insulin;simvastatin;fibrate;erythropoietin;aspirin
18 Does Aldosterone Cause Hypertension by a Non-Renal Mechanism? Unknown status NCT00553722 Phase 4 Eplerenone;Placebo
19 Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation Unknown status NCT00903188 Phase 4 cyclosporine;Everolimus
20 The Effect of Moxonidine on Blood Pressure and Regression of Early Target Organ Damage in Young Subjects With Abdominal Obesity and Hypertension Unknown status NCT01360710 Phase 4 Moxonidine;Irbesartan
21 Effects of Spironolactone in Dialysis Unknown status NCT01128101 Phase 4 Spironolactone
22 RAAS Inhibitor Drugs in Dialysis Patients Unknown status NCT01635387 Phase 4 aliskiren
23 Acthar as Rescue Therapy for Transplant Glomerulopathy in Kidney Transplant Recipients Unknown status NCT02057523 Phase 4 Acthar
24 Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathy Unknown status NCT01673204 Phase 4 Calcitriol;Placebo
25 Diabetes Type 1, Treatment Study Atacand/Placebo After Kidney Biopsy Unknown status NCT00328302 Phase 4 Candesartan;Placebo
26 Intensive Medical Treatment for Nephropathy Caused by Type 2 Diabetes With Hypertension Unknown status NCT00407680 Phase 4 Intensive therapy Valsartan,Fluvastatin
27 Reduction or Discontinuation of CNI's With Conversion to Everolimus-Based Immunosuppresion Unknown status NCT00443508 Phase 4 adding Certican to therapy;reducing Tacrolimus
28 Hemocontrol's Effectiveness on the Reduction of Cardiovascular Long-term EventS Unknown status NCT01515878 Phase 4
29 Study of the Effect of Moxonidine and Diet on Sympathetic Functions in Young Adults With Obesity Unknown status NCT01180231 Phase 4 Moxonidine (Physiotens)
30 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4 valsartan
31 Hypertension Control Based on Home Blood Pressure Unknown status NCT00198562 Phase 4 Amlodipine, Losartan
32 Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin. Unknown status NCT00404599 Phase 4 atrorvastatin 10mg;simvastatin 40mg
33 More Frequent Dialysis (>3 Treatments Per Week) Unknown status NCT00575497 Phase 4
34 Effects of the Use of "de Novo" Everolimus in Renal Tranplant Population Unknown status NCT01663805 Phase 4 Everolimus
35 Treatment of Intracranial Hypertension of Severe Tramatic Brain Injured Patients. Physiopathologic Effects of Neuromuscular Blocking Agents Unknown status NCT02404779 Phase 4 cisatracurium besilate
36 A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus Corticosteroids Unknown status NCT00693446 Phase 4 Sirolimus;Tacrolimus
37 The Effect of Enalapril and Losartan on Peritoneal Membrane in Continuous Ambulatory Peritoneal Dialysis Patients Unknown status NCT01041963 Phase 4 Enalapril;Enalapril plus Losartan;Placebo
38 ACEIs and ARBs Treatment in Diabetic Patients -Drug Interactions and Adverse Drug Effects Unknown status NCT00437775 Phase 4
39 Effects of Antibiotic Prophylaxis on Recurrent UTI in Children Unknown status NCT02357758 Phase 4 Antibiotic Prophylaxis
40 The ACT-OUT Trial: ACTivity OUTcomes Based on High Carbohydrate or High Fat Diet in Metabolic Syndrome Unknown status NCT01357382 Phase 4
41 Renal Sympathetic Denervation in Mild Refractory Hypertension Completed NCT01656096 Phase 4
42 Indapamide Versus Hydrochlorothiazide in Elderly Hypertensive Patients With Renal Insufficiency Completed NCT01172431 Phase 4 Indapamide;Hydrochlorothiazide
43 Renal Response to Lower Body Negative Pressure in Pre-hypertensive States Completed NCT01734096 Phase 4 Candesartan cilexetil
44 Renal and Systemic Vascular Resistance in Chronic Kidney Disease (CKD) Completed NCT01380717 Phase 4 Beta-blocker, ACE-inhibitor;Calcium Channel Blockers, ACE-Inhibitor
45 A Study to Describe Vascular and Renal Effects and Safety of Valsartan in Patients With High Blood Pressure Completed NCT00171353 Phase 4 valsartan
46 Effects of Aliskiren in Elderly Hypertensive Chronic Kidney Disease (CKD) Patients Completed NCT01284114 Phase 4 Aliskiren
47 Nebivolol Effect on Nitric Oxide Levels, Blood Pressure, and Renal Function in Kidney Transplant Patients Completed NCT01157234 Phase 4 Nebivolol;Metoprolol
48 Zainidip in Renal Artery Stenosis Completed NCT02594410 Phase 4 Aspirine;Clopidogrel;Lercanidipine
49 The Effect of Eprosartan on Hormones and Kidney Function in Patients With Essential Hypertension Completed NCT00438945 Phase 4 Eprosartan
50 A Pilot Study of Chlorthalidone Among Patients With Poorly Controlled Hypertension and CKD Completed NCT01750294 Phase 4 Chlorthalidone

Search NIH Clinical Center for Renal Hypertension

Cochrane evidence based reviews: hypertension, renal

Genetic Tests for Renal Hypertension

Anatomical Context for Renal Hypertension

MalaCards organs/tissues related to Renal Hypertension:

39
Kidney, Heart, Endothelial, Liver, Testes, Lung, Bone

Publications for Renal Hypertension

Articles related to Renal Hypertension:

(show top 50) (show all 512)
id Title Authors Year
1
Flax lignan concentrate reverses alterations in blood pressure, left ventricular functions, lipid profile and antioxidant status in DOCA-salt induced renal hypertension in rats. ( 26795298 )
2016
2
Hydroalcoholic extract of Allium eriophyllum leaves attenuates cardiac impairment in rats with simultaneous type 2 diabetes and renal hypertension. ( 26487889 )
2015
3
The cardioprotective effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension. ( 25920277 )
2015
4
The effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension: a study of antihypertensive mechanisms. ( 25821295 )
2015
5
Editorial (thematic issue: all roads of renal hypertension lead to or come from CKD). ( 25549836 )
2014
6
Renal hypertension and cardiovascular disorder in children with chronic kidney disease. ( 24684043 )
2014
7
Oleuropein offers cardioprotection in rats with simultaneous type 2 diabetes and renal hypertension. ( 25097277 )
2014
8
Curable renal hypertension: renin, marker or cause? Question answered. ( 25103928 )
2014
9
Effects of oleuropein in rats with simultaneous type 2 diabetes and renal hypertension: a study of antihypertensive mechanisms. ( 24954237 )
2014
10
Renal denervation for resistant hypertension using an irrigated radiofrequency balloon: 12-month results from the Renal Hypertension Ablation System (RHAS) trial. ( 23685297 )
2013
11
Renal hypertension: an unusual cause for a common problem. ( 23371394 )
2013
12
Simultaneous renal hypertension and type 2 diabetes exacerbate vascular endothelial dysfunction in rats. ( 22458508 )
2012
13
ESPR uroradiology task force and ESUR paediatric working group: imaging recommendations in paediatric uroradiology, part IV: Minutes of the ESPR uroradiology task force mini-symposium on imaging in childhood renal hypertension and imaging of renal trauma in children. ( 21710387 )
2011
14
Effect of age and sex on blood pressure, development of renal hypertension, and concentration of nitric oxide in the blood of albino rats. ( 21113443 )
2010
15
Comprehensive evaluation of patients with suspected renal hypertension using MDCT: from protocol to interpretation. ( 19380531 )
2009
16
Effectiveness of unilateral nephrectomy for renal hypertension in adults. ( 19010760 )
2008
17
Cardiovascular reactivity in patients with essential or renal hypertension under standardized mental stress. ( 17653965 )
2007
18
Renal capsular PEComa--a rare cause of surgically correctable renal hypertension. ( 17318350 )
2007
19
Cardiovascular reactivity of patients with essential and renal hypertension in an emotion-triggering interview. ( 17348427 )
2007
20
Total peripheral resistance responsiveness during the development of secondary renal hypertension in dogs. ( 17278982 )
2007
21
Correction of renal hypertension after kidney transplantation from a donor with Gitelman syndrome. ( 16479187 )
2006
22
Ventricular structure and function in aged dogs with renal hypertension: a model of experimental diastolic heart failure. ( 15723971 )
2005
23
Water intake during the development of renal hypertension (2K-1C) in mice. ( 15992836 )
2005
24
Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child. ( 15711357 )
2005
25
Cardiovascular hypertrophy in one-kidney, one-clip renal hypertension is resistant to heparin. ( 15126919 )
2004
26
Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child. ( 14678186 )
2004
27
[Clinical observation of the therapeutic effect of valsartan for renal hypertension in 64 cases]. ( 13129740 )
2003
28
Mild renal hypertension alters run training effects on the frequency response of rat cardiomyocyte mechanics. ( 12857770 )
2003
29
The role of partial nephrectomy in the treatment of pediatric renal hypertension. ( 12544329 )
2003
30
Mouse model of cerebral aneurysm: experimental induction by renal hypertension and local hemodynamic changes. ( 12105374 )
2002
31
Neurohormonal influences on maintenance and reversal of two-kidney one-clip renal hypertension. ( 12100364 )
2002
32
Sympathetic nervous system function in renal hypertension. ( 12003706 )
2002
33
Neurogenic factors in renal hypertension. ( 12003710 )
2002
34
Factors influencing acute ischaemia-induced renal hypertension in rats. ( 12473871 )
2002
35
Renal hypertension prevents run training modification of cardiomyocyte diastolic Ca2+ regulation in male rats. ( 11356766 )
2001
36
Altered contractions to endothelin-1, phenylephrine, potassium chloride and relaxations to acetylcholine at various stages of renal hypertension in the rat. ( 11401413 )
2001
37
Role of angiotensin II and free radicals in blood pressure regulation in a rat model of renal hypertension. ( 11566905 )
2001
38
Effects of YM358, an angiotensin II type 1 (AT1) receptor antagonist, and enalapril on blood pressure and vasoconstriction in two renal hypertension models. ( 10706380 )
2000
39
Acute AT1 receptor blockade does not improve the depressed baroreflex in rats with chronic renal hypertension. ( 11105103 )
2000
40
Plasma-levels of endothelin-1 and angiotensin-II and reactivity of arterial blood pressure to exogenous sympathomimetics and vasoactive peptides in rat model of malignant renal hypertension. ( 10870254 )
2000
41
Poland's syndrome--complicated with renal hypertension. ( 11273191 )
2000
42
Effect of ramipril on ambulatory blood pressure and albuminuria in renal hypertension. ( 11095026 )
2000
43
AT(1) receptor inhibition does not reduce arterial wall hypertrophy or PDGF-A expression in renal hypertension. ( 10666094 )
2000
44
Plasma brain natriuretic peptides and renal hypertension. ( 10955934 )
2000
45
[The protection of renal function in the ACEI treatment of renal hypertension]. ( 12206011 )
2000
46
Serial magnetic resonance imaging of rat brain after induction of renal hypertension. ( 10548682 )
1999
47
[Study on the relationship between plasma endothelin nitric oxide concentration and renal hypertension and renal function]. ( 12080656 )
1999
48
Decreased diurnal blood pressure variability and low dehydroepiandrosterone sulfate levels in patients with renal hypertension, and after kidney transplantation. ( 10463206 )
1999
49
How reproducible is diurnal blood pressure rhythm in patients with secondary (renal) hypertension? ( 10756891 )
1999
50
Comparison of tumour necrosis factor and endothelin-1 between essential and renal hypertensive patients. ( 9705035 )
1998

Variations for Renal Hypertension

Expression for Renal Hypertension

Search GEO for disease gene expression data for Renal Hypertension.

Pathways for Renal Hypertension

Pathways related to Renal Hypertension according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.94 ADM EDN1 EPO
2 10.61 ACE AGTR1 REN
3 10.52 ADM DBH

GO Terms for Renal Hypertension

Cellular components related to Renal Hypertension according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 ACE ADM ALB DBH EDN1 EPO
2 extracellular space GO:0005615 9.32 ACE ADM ALB DBH EDN1 EPO

Biological processes related to Renal Hypertension according to GeneCards Suite gene sharing:

(show all 21)
id Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.73 ACE AGTR1 REN
2 positive regulation of cytosolic calcium ion concentration GO:0007204 9.67 ADM AGTR1 EDN1 KNG1
3 blood vessel remodeling GO:0001974 9.6 ACE DBH
4 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway GO:0051482 9.59 AGTR1 EDN1
5 positive regulation of heart rate GO:0010460 9.58 ADM EDN1
6 blood coagulation, intrinsic pathway GO:0007597 9.58 KLKB1 KNG1
7 response to hypoxia GO:0001666 9.58 ADM EDN1 EPO
8 beta-amyloid metabolic process GO:0050435 9.57 ACE REN
9 negative regulation of blood coagulation GO:0030195 9.55 EDN1 KNG1
10 positive regulation of renal sodium excretion GO:0035815 9.54 EDN1 NPPB
11 positive regulation of urine volume GO:0035810 9.52 EDN1 NPPB
12 response to dexamethasone GO:0071548 9.51 EDN1 EPO
13 regulation of vasoconstriction GO:0019229 9.5 ACE AGTR1 EDN1
14 angiotensin maturation GO:0002003 9.49 ACE REN
15 body fluid secretion GO:0007589 9.48 EDN1 NPPB
16 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.46 ACE AGTR1
17 renin-angiotensin regulation of aldosterone production GO:0002018 9.43 AGTR1 REN
18 regulation of blood vessel size GO:0050880 9.43 EDN1 KNG1 NPPB
19 regulation of blood vessel diameter GO:0097746 9.33 ACE AGTR1 NPPB
20 regulation of blood pressure GO:0008217 9.26 ACE EDN1 NPPB REN
21 response to lipopolysaccharide GO:0032496 8.92 ADM EDN1 EPO REN

Molecular functions related to Renal Hypertension according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.55 ADM EDN1 KNG1 NPPB REN
2 bradykinin receptor binding GO:0031711 8.96 ACE AGTR1
3 hormone activity GO:0005179 8.92 ADM EDN1 EPO NPPB

Sources for Renal Hypertension

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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