Renal Oncocytoma malady

Wikipedia: A renal oncocytoma is a tumour of the kidney made up of oncocytes, a special kind of cell.⁴⁴ more...

MalaCards: Renal Oncocytoma, also known as renal epithelial oncocytic tumor, is related to oxyphilic adenoma and renal cell carcinoma. An important gene associated with Renal Oncocytoma is CLDN8 (claudin 8), and among its related pathways are Cytoskeleton remodeling Keratin filaments and Cytoskeleton remodeling_Keratin filaments. The compounds eosin and monochloroacetic acid have been mentioned in the context of this disorder. Affiliated tissues include kidney, and related mouse phenotypes are liver/biliary system and hematopoietic system.

Aliases & Descriptions:

renal oncocytoma 6 30 8 renal epithelial oncocytic tumor 6 oncocytoma of kidney (disorder) 6 hurthle cell tumor 43

oncocytoma, renal 43 oncocytoma kidney 30 oncocytoma renal 30

Diseases related to renal oncocytoma by text searches and GeneDecks gene sharing:

(show top 50)    (show all 372)

id	Related Disease	Score	Top Affiliating Genes
1	oxyphilic adenoma	29.8	CLDN7, CLDN8, S100A1, CDH16, FLCN, PVALB
2	renal cell carcinoma	29.3	KIT, PCNA, VIM, VHL, CLDN7, CLDN8
3	chromophobe renal cell carcinoma	29.3	KIT, PCNA, VIM, VHL, CLDN7, CLDN8
4	mitochondrial complex i deficiency	29.0	MT-ND3, FH, NDUFS4
5	conjunctivitis	27.9	KITLG, VIM, AQP6, CCND1, TP53, KRT20
6	carcinoma	24.8	KIT, KITLG, PCNA, VIM, VHL, CLDN7
7	uterine benign neoplasm	13.7	MAGEA4, CTAG1B
8	ovarian large-cell neuroendocrine carcinoma	13.6	KRT7, KRT20
9	paraurethral gland neoplasm	13.6	KRT7, KRT20
10	dermoid cyst of ovary	13.5	VIM, KRT20
11	papillary adenoma	13.5	VIM, KRT7, PRCC
12	hereditary leiomyomatosis and renal cell cancer	13.5	SDHB, FH
13	pancreatic ductal carcinoma	13.5	KRT8, KRT7, KRT20
14	bladder adenocarcinoma	13.5	KRT7, KRT20
15	mucinous ovarian cystadenoma	13.5	KRT7, KRT20, PSG2
16	indolent systemic mastocytosis	13.4	KIT, KITLG
17	mammary paget's disease	13.4	KRT8, KRT7, KRT14
18	nephrogenic adenoma	13.4	MUC1, CDH16, KRT7
19	horseshoe kidney	13.4	MME, KRT7, KRT20
20	clear cell ependymoma	13.3	VIM, MUC1
21	prostate stromal sarcoma	13.3	VIM, MUC1
22	chondroblastoma	13.3	VIM, S100A1, KRT8, KRT7
23	malignant peripheral nerve sheath tumor	13.3	KIT, VIM, S100A1
24	pancreatic mucinous cystadenoma	13.3	KIT, MME, KRT20
25	chondroma	13.3	KIT, SDHB, S100A1
26	ossifying fibromyxoid tumor	13.3	VIM, S100A1, MME
27	mast-cell sarcoma	13.3	KIT, KITLG, VIM
28	vhl-related pheochromocytoma	13.3	VHL, SDHB
29	pseudomyxoma peritonei	13.3	VIM, KRT7, KRT20, PSG2
30	aggressive systemic mastocytosis	13.3	KIT, KITLG
31	mucinous cystadenocarcinoma	13.3	MUC1, KRT7, KRT20
32	ampulla of vater adenocarcinoma	13.3	MUC1, KRT7, KRT20
33	spindle cell sarcoma	13.3	VIM, MUC1, KRT7
34	metanephric adenoma	13.3	VIM, MUC1, KRT7
35	cutaneous paget's disease	13.3	MUC1, KRT7, KRT20
36	adenoid squamous cell carcinoma	13.3	VIM, MUC1
37	endometrial mucinous adenocarcinoma	13.3	VIM, MUC1
38	breast malignant phyllodes tumor	13.3	KIT, VIM, MME
39	clear cell meningioma	13.3	VIM, MUC1
40	myxopapillary ependymoma	13.3	VIM, MUC1, KRT7
41	chondroid chordoma	13.3	VIM, MUC1, S100A1
42	chordoid glioma	13.3	VIM, MUC1, KRT7
43	endometrial stromal sarcoma	13.3	KIT, VIM, MME
44	biphasic synovial sarcoma	13.3	VIM, MUC1, CTAG1B
45	sex cord-gonadal stromal tumor	13.2	VIM, MUC1, KRT7
46	sarcomatoid mesothelioma	13.2	VIM, MUC1, S100A1
47	familial renal cell carcinoma	13.2	VHL, SDHB, FH
48	mesenchymal chondrosarcoma	13.2	VIM, MUC1
49	hereditary pancreatitis	13.2	MAGEA4, CTAG1B, KRT8, PSG2
50	malignant mixed mullerian tumor	13.2	VIM, TP53, KRT7

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to renal oncocytoma:

²²

MGI Mouse Phenotypes related to renal oncocytoma:

²⁵ (show all 11)

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	liver/biliary system phenotype	MP:0005370	9.1	TP53, VHL, KIT
2	hematopoietic system phenotype	MP:0005397	8.1	EPCAM, EGLN2, KRT8, CCND1, CD3E, MST1R
3	muscle phenotype	MP:0005369	7.8	PVALB, EGLN2, NDUFS4, TP53, CAV1, ANKRD2
4	immune system phenotype	MP:0005387	7.7	NDUFS4, KRT14, KRT8, TP53, CCND1, MME
5	tumorigenesis	MP:0002006	7.5	KRT14, TP53, CAV1, CCND1, FLCN, MUC1
6	cardiovascular system phenotype	MP:0005385	6.8	NDUFS4, KRT8, TP53, CAV1, CCND1, FLCN
7	mortality/aging	MP:0010768	6.8	EPCAM, KRT14, KRT8, TP53, CAV1, CCND1
8	integument phenotype	MP:0010771	6.2	KIT, EGLN2, NDUFS4, KRT14, DLG2, TP53
9	reproductive system phenotype	MP:0005389	6.2	CAV1, TP53, KRT8, KRT14, EGLN2, ROS1
10	homeostasis/metabolism phenotype	MP:0005376	6.0	CCND1, CAV1, TP53, KRT14, NDUFS4, EGLN2
11	cellular phenotype	MP:0005384	5.9	EPCAM, PVALB, EGLN2, NDUFS4, KRT14, TP53

Articles related to renal oncocytoma:

(show all 46)

id	Title	Authors	Year	Affiliating Genes
1	Immunohistochemical expression of tumor antigens MAGE -A3/4 and NY-ESO-1 in renal oncocytoma and chromophobe renal cell carcinoma. (20591578)	DemiroviA8 A.... KruA!lin B.	2010	MAGEA4, MAGEA3, CTAG1B
2	Gene expression profiling of chromophobe renal cell c arcinomas and renal oncocytomas by Affymetrix GeneChip using pooled and individ ual tumours. (19680475)	Yusenko M.V.... Kovacs G.	2009	S100A1, CD82, AQP6
3	Immunohistochemical stain for cytokeratin 7, S100A1 and claudin 8 is valuable in differential diagnosis of chromophobe renal cell carcinoma from renal oncocytoma. (19302533)	Kim S.S.... Choi C.	2009	KRT7, S100A1, CLDN8
4	Does CD10 immunoexpression have a diagnostic utility in the differential diagnosis of renal oncocytomas and eosinophilic variants of chromophobe renal cell carcinomas? (19152193)	Mete O.... Uysal V.	2009	MME
5	Oncocytic renal cell carcinoma with immunohistochemical properties of renal oncocytoma. (18947937)	Mai K.T.... Belanger E.C.	2009	KIT, VIM, KRT7
6	CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differ entiation from chromophobe renal cell carcinoma. (19386349)	Sukov W.R.... Cheville J.C.	2009	CCND1
7	Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma. (18799195)	Osunkoya A.O.... Young A.N.	2009	CLDN7, CLDN8
8	SDHB-associated renal oncocytoma suggests a broadenin g of the renal phenotype in hereditary paragangliomatosis. (19184535)	Henderson A.... Maher E.R.	2009	SDHB
9	Renal oncocytoma with and without intravascular exten sion into the branches of renal vein have the same morphological, immunohistoch emical, and genetic features. (18066590)	Hes O.... Yang X.	2008	PVALB
10	Renal oncocytoma with and without intravascular exten sion into the branches of renal vein have the same morphological, immunohistoch emical and genetic features. (18196270)	Hes O.... Yang X.	2008	PVALB
11	Somatic pairing of chromosome 19 in renal oncocytoma is associated with deregulated ELGN2-mediated oxygen-sensing response. (18773095)	Koeman J.M.... Furge K.A.	2008	EGLN2
12	Vimentin reactivity in renal oncocytoma: immunohistochemical study of 234 cases. (18081436)	Hes O.... Yang X.J.	2007	VIM
13	Claudin-7 is highly expressed in chromophobe renal cell carcinoma and renal oncocytoma. (17449941)	Choi Y.D.... Choi C.	2007	CLDN7, PVALB
14	S100A1: a powerful marker to differentiate chromophobe renal cell carcinoma from renal oncocytoma. (17394501)	Li G.... Tostain J.	2007	S100A1
15	Immunohistochemical analysis of chromophobe renal cell carcinoma, renal oncocytoma, and clear cell carcinoma: an optimal and practical panel for differential diagnosis. (17683191)	Liu L.... Bostwick D.G.	2007	KIT, VIM, KRT7
16	ARPP protein is selectively expressed in renal oncocytoma, but rarely in renal cell carcinomas. (17206105)	Shomori K.... Moriyama M.	2007	ANKRD2
17	Diagnostic value of cytokeratin 7 and parvalbumin in differentiating chromophobe renal cell carcinoma from renal oncocytoma. (16927643)	Adley B.P.... Yang X.J.	2006	KRT7, PVALB
18	Differential expression of a new isoform of DLG2 in renal oncocytoma. (16640776)	Zubakov D.... Kovacs G.	2006	DLG2
19	Expression of kidney-specific cadherin in chromophobe renal cell carcinoma and renal oncocytoma. (16753598)	Adley B.P.... Yang X.J.	2006	CDH16
20	Caveolin-1 immunohistochemical analysis in differentiating chromophobe renal cell carcinoma from renal oncocytoma. (16613342)	Garcia E.... Li M.	2006	CAV1, KRT7
21	Cytokeratin 14 is not a specific marker for renal oncocytomas. (17001169)	Nordling S.	2006	KRT14
22	C-kit expression in renal oncocytomas and chromophobe renal cell carcinomas. (15791570)	Huo L.... Yang X.J.	2005	KIT
23	Insertion (8;11) in a renal oncocytoma with multifocal transformation to chromophobe renal cell carcinoma. (16337860)	Salido M.... SolAc F.	2005	CCND1
24	Expression of CD3 antigens in renal tubule epithelium and renal oncocytomas. (16308105)	Alroy J.... Cheville J.C.	2005	CD3E
25	Expression of KIT (CD117) in renal cell carcinoma and renal oncocytoma. (16015044)	Kruger S.... Horny H.P.	2005	KIT, KITLG
26	Renal oncocytoma with loss of chromosomes Y and 1 evolving to papillary carcinoma in connection with gain of chromosome 7. Coincidence or progression? (16271962)	Al-Saleem T.... Greenberg R.E.	2005	VIM, KRT7
27	Can renal oncocytoma be differentiated from its renal mimics? The utility of anti-mitochondrial, caveolin 1, CD63 and cytokeratin 14 antibodies in the differential diagnosis. (16133362)	Mete O.... Uysal V.	2005	CAV1, KRT14
28	Expression of kidney-specific cadherin distinguishes chromophobe renal cell carcinoma from renal oncocytoma. (15712178)	Mazal P.R.... Susani M.	2005	VIM, KRT7, CDH16
29	Immunohistochemical identification of intracytoplasmic lumens by cytokeratin typing may differentiate renal oncocytomas from chromophobe renal cell carcinomas. (14702167)	Kuroda N.... Enzan H.	2004	KRT7
30	Overexpression of KIT (CD117) in chromophobe renal cell carcinoma and renal oncocytoma. (15198361)	Pan C.C.... Chiang H.	2004	KIT
31	Keratin immunohistochemistry in renal cell carcinoma subtypes and renal oncocytomas: a systematic analysis of 233 tumors. (14727107)	Langner C.... Zigeuner R.	2004	VIM, KRT8, KRT20
32	The diagnostic utility of MOC31, BerEP4, RCC marker and CD10 in the classification of renal cell carcinoma and renal oncocytoma: an immunohistochemical analysis of 328 cases. (15500648)	Pan C.C.... Ho D.M.	2004	VIM, MME, MUC1
33	Lack of mutation of the folliculin gene in sporadic chromophobe renal cell carcinoma and renal oncocytoma. (14961590)	Nagy A.... Kovacs G.	2004	FLCN
34	The Ron proto-oncogene product is a phenotypic marker of renal oncocytoma. (12766581)	Rampino T.... Dal Canton A.	2003	MST1R
35	Mitochondrial complex I is deficient in renal oncocytomas. (12844484)	Simonnet H.... Godinot C.	2003	FH, NDUFS4
36	Cytokeratin 20 immunoreactivity in renal oncocytomas. (11410616)	Stopyra G.A.... Multhaupt H.A.	2001	KRT20
37	Can renal oncocytomas be distinguished from renal cell carcinoma on fine-needle aspiration specimens? A study of conventional smears in conjunction with ancillary studies. (11748579)	Liu J.... Fanning C.V.	2001	VIM
38	Utility of cytokeratin 7 for distinguishing chromophobe renal cell carcinoma from renal oncocytoma. (10765081)	Leroy X.... Gosselin B.	2000	KRT7
39	Pathology and proliferative activity of renal-cell carcinomas (RCCS) and renal oncocytomas in patients with different radiation exposure after the Chernobyl accident in Ukraine. (10956401)	Romanenko A.... Llombart-Bosch A.	2000	PCNA
40	Bilateral multiple renal oncocytomas and cysts associated with a constitutional translocation (8;9)(q24.1;q34.3) and a rare constitutional VHL missense substitution. (9523203)	Teh B.T.... Nicol D.	1998	VHL
41	Biological properties of renal oncocytoma cells in culture. (8659013)	Hawkins N.J.... Ward R.L.	1996	TP53
42	Renal oncocytoma mimicking hemorrhagic renal cyst. (8749955)	Sekido N.... Koiso K.	1995	PSG2
43	Cytokeratin-containing globular filamentous bodies in renal oncocytoma. (1721750)	Bonsib S.M.... Bray C.	1991	VIM
44	Renal cell carcinoma vs. renal oncocytoma. Report of a case with overlap features and review of the literature. (1986475)	Lazzaro B.... Katz S.M.	1991	VIM
45	Renal oncocytoma: diagnostic utility of cytokeratin-containing globular filamentous bodies. (1708500)	Bonsib S.M.... Lager D.J.	1991	VIM
46	Mitochondrial adenosine triphosphatase in the oxyphil cells of a renal oncocytoma. (2138585)	Hunter V.R.... Beckner M.E.	1990	ATP5E

Genes related to renal oncocytoma according to GeneCards:

(show all 40)

id	Symbol	Description	Score	GeneCards Section Context
1	CLDN8	claudin 8	11.1	Publications, Summaries
2	CDH16	cadherin 16, KSP-cadherin	11.0	Publications
3	SYNGR3	synaptogyrin 3	11.0
4	CLDN7	claudin 7	11.0	Publications
5	AQP6	aquaporin 6, kidney specific	11.0	Publications
6	ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	11.0	Publications
7	KRT7	keratin 7	11.0	Publications
8	EGLN2	egl nine homolog 2 (C. elegans)	11.0	Publications
9	FLCN	folliculin	11.0	Publications
10	ATP5E	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit	11.0	Publications
11	MAGEA4	melanoma antigen family A, 4	11.0	Publications
12	PVALB	parvalbumin	11.0	Publications
13	MST1R	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	11.0	Publications
14	S100A1	S100 calcium binding protein A1	11.0	Publications
15	MAGEA3	melanoma antigen family A, 3	11.0	Publications
16	FH	fumarate hydratase	11.0	Publications
17	CD3E	CD3e molecule, epsilon (CD3-TCR complex)	11.0	Publications
18	CTAG1B	cancer/testis antigen 1B	11.0	Publications
19	KRT14	keratin 14	11.0	Publications
20	CD82	CD82 molecule	11.0	Publications
21	VIM	vimentin	11.0	Publications
22	KRT20	keratin 20	11.0	Publications
23	EPCAM	epithelial cell adhesion molecule	11.0	Publications
24	SDHB	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	11.0	Publications
25	PRCC	papillary renal cell carcinoma (translocation-associated)	11.0
26	PSG2	pregnancy specific beta-1-glycoprotein 2	11.0	Publications
27	KRT8	keratin 8	11.0	Publications
28	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	11.0	Publications
29	ROS1	c-ros oncogene 1 , receptor tyrosine kinase	11.0
30	CAV1	caveolin 1, caveolae protein, 22kDa	11.0	Publications
31	KITLG	KIT ligand	11.0	Publications
32	VHL	von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase	11.0	Publications
33	MME	membrane metallo-endopeptidase	11.0	Publications
34	NDUFS4	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	11.0	Publications
35	MUC1	mucin 1, cell surface associated	11.0	Publications
36	CCND1	cyclin D1	11.0	Publications
37	PCNA	proliferating cell nuclear antigen	11.0	Publications
38	MT-ND3	mitochondrially encoded NADH dehydrogenase 3	11.0
39	TP53	tumor protein p53	11.0	Publications
40	DLG2	discs, large homolog 2 (Drosophila)	11.0	Publications

Pathways related to renal oncocytoma according to GeneDecks:

(show all 12)

id	Pathway	Score	Top Affiliating Genes
1	Cytoskeleton remodeling Keratin filaments10	10.0	KRT14, KRT7, KRT8, VIM
2	Cytoskeleton remodeling_Keratin filaments41	10.0	VIM, KRT8, KRT7, KRT14
3	Renal cell carcinoma20	9.9	VHL, FH, EGLN2
4	Cytoskeletal Signaling3	9.4	VIM, CAV1, KRT8, KRT7, EPCAM
5	Hematopoietic cell lineage20	9.4	MME, CD3E, KITLG, KIT
6	Lymphocyte Signaling3	9.4	MME, CD3E, CD82, KITLG, KIT
7	Pathways in cancer20	9.3	FH, CCND1, TP53
8	eNOS Signaling36	9.2	ROS1, CAV1, AQP6, MST1R, KITLG, KIT
9	ILK Signaling36	8.6	KIT, ROS1, CCND1, CDH16, MST1R, MUC1
10	GADD45 Pathway36	8.6	PCNA, CCND1, TP53
11	Pancreatic Adenocarcinoma36	8.4	ROS1, TP53, CCND1, MST1R, KITLG, KIT
12	Breast Cancer Regulation by Stathmin136	7.9	ROS1, TP53, CCND1, MST1R, KITLG, KIT

Compounds related to renal oncocytoma according to GeneDecks:

(show top 50)    (show all 74)

id	Compound	Score	Top Affiliating Genes
1	eosin32	10.1	MUC1, VIM
2	monochloroacetic acid32	10.0	VIM, KITLG, KIT
3	toluidine32	10.0	S100A1, VIM, KITLG, KIT
4	roscovitine32	9.8	PCNA, VIM
5	mucicarmine32	9.7	KRT14, KRT20, KRT7, S100A1, MUC1, VIM
6	2-methoxyethanol32	9.7	VIM, S100A1, KRT14
7	alpha-ketoglutarate32	9.6	EGLN2, NDUFS4, FH, SDHB, VHL
8	reticulin32	9.6	KRT7, MUC1, VIM, PCNA
9	pyruvate32	9.3	NDUFS4, FH, MT-ND3, SDHB
10	glucose32	9.2	PSG2, KRT7, KRT8, FH, MME, VHL
11	estrogen32	9.2	PVALB, KRT14, KRT20, KRT8, S100A1, VHL
12	retinoic acid32 42 18	11.2	KRT7, KRT8, CCND1, MME, KITLG, KIT
13	oxygen32 18	10.2	NDUFS4, CAV1, FH, SDHB, KITLG
14	biotin32 9 18 9	12.1	S100A1, MUC1, VIM, PCNA, KITLG
15	gold32	9.1	PSG2, KRT8, CAV1, MUC1, KITLG, KIT
16	methotrexate32 34 42 9 9	12.9	KRT7, MUC1, VIM, PCNA, KITLG, KIT
17	b 72332	8.9	PSG2, KRT20, KRT7, KRT8, S100A1, MUC1
18	matrigel32	8.7	KRT7, KRT8, CAV1, CCND1, MME, MUC1
19	agar32	8.7	KRT8, CAV1, CCND1, MUC1, VIM, KITLG
20	crcs32	8.7	TP53, CCND1, MME, MUC1
21	bromodeoxyuridine32	8.6	KRT14, KRT8, CCND1, MME, VIM, PCNA
22	2-methoxyestradiol32 18	9.5	TP53, CAV1, CCND1, PCNA
23	hematoxylin32	8.5	PSG2, KIT, PCNA, VIM, MUC1, S100A1
24	cysteine32	8.4	NDUFS4, KRT14, KRT8, CAV1, S100A1, MUC1
25	formaldehyde32 18	9.4	PSG2, PVALB, KRT20, KRT7, CCND1, MUC1
26	retinoid32	8.4	KRT14, KRT7, KRT8, TP53, CCND1, VIM
27	glycogen32 18	9.3	CCND1, KRT8, KRT7, PSG2, S100A1, MUC1
28	creatinine32	8.2	PSG2, KRT8, FH, MME, MUC1, SDHB
29	adriamycin32	8.2	PSG2, KRT8, TP53, CCND1, MME, MUC1
30	5-aza-2deoxycytidine32	8.2	KRT7, CTAG1B, TP53, CAV1, VHL, VIM
31	iron32 18	9.1	PVALB, EGLN2, NDUFS4, KRT14, KRT20, KRT7
32	5fluorouracil32	8.1	EPCAM, PSG2, TP53, MUC1, PCNA, KITLG
33	cytarabine32 34 9 9	11.0	TP53, MME, MUC1, VIM, PCNA, KITLG
34	nitric oxide32 9 18 9	11.0	PSG2, PVALB, NDUFS4, CAV1, MME, S100A1
35	lactate32	8.0	PSG2, NDUFS4, KRT8, FH, MME, ATP5E
36	actinomycin d32	7.9	KRT8, TP53, MME, MUC1, VHL, VIM
37	paclitaxel32 34 9 9	10.8	KRT8, TP53, CAV1, CCND1, VIM, PCNA
38	tamoxifen32 34 9 9	10.8	KRT14, KRT8, TP53, CAV1, CCND1, MUC1
39	butyrate32	7.8	KRT14, KRT8, TP53, CCND1, MUC1, VIM
40	cycloheximide32	7.7	KRT8, TP53, CAV1, CCND1, MME, VIM
41	cisplatin32 34 9 9	10.5	KRT14, KRT8, TP53, CAV1, CCND1, MUC1
42	oligonucleotide32	7.5	KRT8, TP53, CAV1, CCND1, MAGEA3, CLDN7
43	testosterone32 9 18 9	10.4	CCND1, CAV1, KRT8, KRT7, KRT20, MME
44	thymidine32 18	8.3	EPCAM, PSG2, TP53, CCND1, MME, MUC1
45	doxorubicin32 34 9 9	10.2	PSG2, NDUFS4, KRT20, KRT8, TP53, CAV1
46	progesterone32 42 9 18 9	10.8	TP53, KRT8, KRT7, KRT20, KRT14, CAV1
47	tyrosine32	6.6	CCND1, CAV1, KRT8, KRT7, KRT20, KRT14
48	vegf32	5.9	CAV1, TP53, KRT8, KRT7, KRT20, EGLN2
49	serine32	5.8	CAV1, TP53, KRT8, KRT14, NDUFS4, PVALB
50	paraffin32	5.6	PVALB, PSG2, EPCAM, KRT14, KRT20, KRT7

Cellular components related to renal oncocytoma according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	intermediate filament	GO:005882	9.6	VIM, KRT8, KRT7, KRT20, KRT14

Biological processes related to renal oncocytoma according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	germ cell programmed cell death	GO:035234	9.9	KIT, KITLG

Molecular functions related to renal oncocytoma according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	structural molecule activity	GO:005198	9.3	KRT7, KRT8, CAV1, CLDN8, CLDN7
2	identical protein binding	GO:042802	8.5	TP53, S100A1, CLDN8, CLDN7, VIM, PCNA
3	enzyme binding	GO:019899	8.5	VHL, MST1R, CCND1, CAV1, TP53
4	protein binding	GO:005515	3.6	EPCAM, MAGEA4, CCND1, CAV1, TP53, DLG2