MCID: RNL017
MIFTS: 36

Renal Oncocytoma malady

Summaries for Renal Oncocytoma

Sources:
64Wikipedia, 47OMIM, 33MalaCards
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Wikipedia:64 A renal oncocytoma is a tumour of the kidney made up of oncocytes, a special kind of cell. more...

MalaCards: Renal Oncocytoma, also known as renal epithelial oncocytic tumor, is related to papillary carcinoma and adenoma. An important gene associated with Renal Oncocytoma is MT-ND3 (mitochondrially encoded NADH dehydrogenase 3), and among its related pathways are Cytoskeleton remodeling Keratin filaments and Cell-cell junction organization. The compounds reticulin and 2-methoxyethanol have been mentioned in the context of this disorder.

Description from OMIM:47 553000

Aliases & Classifications for Renal Oncocytoma

Sources:
8Disease Ontology, 43NIH Rare Diseases, 10DISEASES, 61UMLS, 47OMIM, 57SNOMED-CT, 40NCIt, 35MeSH
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Aliases & Descriptions:

renal oncocytoma 8 43 10
renal epithelial oncocytic tumor 8
oncocytoma of kidney 8
hurthle cell tumor 61
oncocytoma kidney 43
oncocytoma, renal 61
oncocytoma renal 43


External Ids:

Disease Ontology8 DOID:6245
OMIM47 553000
SNOMED-CT57 254922006
NCIt40 C4526
MeSH35 C537750

Related Diseases for Renal Oncocytoma

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Renal Oncocytoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 80)
idRelated DiseaseScoreTop Affiliating Genes
1papillary carcinoma30.5KRT7, KRT14, S100A1
2adenoma30.4KRT7, KRT14, S100A1
3renal clear cell carcinoma30.4VIM, PVALB, S100A1, CDH16, CLDN7, KRT7
4angiomyolipoma30.3VIM, S100A1
5oxyphilic adenoma30.2KRT7, KRT14, CLDN7, CDH16, FLCN, S100A1
6paraganglioma30.1S100A1
7adenocarcinoma30.1VIM, CTAG1B, MAGEA3, MAGEA4, CLDN7, KRT14
8chromophobe renal cell carcinoma10.8
9familial renal oncocytoma10.4
10papillary renal carcinoma10.4
11papillary renal cell carcinoma10.3
12clear cell renal cell carcinoma10.3
13tuberous sclerosis10.2
14thyroid hurthle cell carcinoma10.2
15bullous pemphigoid10.1
16bone carcinoma10.1
17coronary aneurysm10.1
18small cell carcinoma10.1
19bronchogenic carcinoma10.1
20granular cell carcinoma10.1
21chromophobe adenoma10.1
22diffuse large b-cell lymphoma10.1
23n syndrome10.1
24osteoporosis10.1
25amyloidosis10.1
26vasculitis10.1
27pheochromocytoma10.1
28coronary artery aneurysm10.1
29amyloidosis, renal10.1
30lymphoma, diffuse large cell10.1
31erythrocytosis10.1
32polyploidy10.1
33mixed cell type cancer10.0KRT7
34dysgerminoma10.0KRT7
35thymic carcinoma10.0KRT7
36craniopharyngioma10.0KRT14
37papilloma10.0KRT14
38endometrial carcinoma10.0KRT7
39ductal carcinoma in situ10.0KRT14
40lipoma10.0S100A1
41nephrogenic adenoma10.0KRT7, S100A1
42cystadenoma10.0KRT7
43epithelial-myoepithelial carcinoma10.0KRT14
44metanephric adenoma10.0KRT7
45syringoma10.0S100A1, KRT14
46kidney cancer10.0FLCN, CDH16, KRT7
47lung cancer10.0KRT7, MAGEA3
48rhabdomyosarcoma10.0S100A1, VIM
49spindle cell sarcoma10.0KRT7, VIM
50colorectal cancer10.0KRT7, KRT14, MAGEA3

Graphical network of the top 20 diseases related to Renal Oncocytoma:



Diseases related to renal oncocytoma

Clinical Features for Renal Oncocytoma

Sources:
47OMIM
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Clinical features from OMIM:

553000

Drugs & Therapeutics for Renal Oncocytoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Renal Oncocytoma

Drug clinical trials:

Search ClinicalTrials for Renal Oncocytoma

Search NIH Clinical Center for Renal Oncocytoma

Search CenterWatch for Renal Oncocytoma

Genetic Tests for Renal Oncocytoma

Anatomical Context for Renal Oncocytoma

Animal Models for Renal Oncocytoma or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Renal Oncocytoma

Sources:
51PubMed
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Articles related to Renal Oncocytoma:

(show top 50)    (show all 360)
idTitleAuthorsYear
1
Simultaneous renal oncocytoma and lymphoma: interest of lymphadenectomy. (23984175)
2013
2
Immunohistochemical application of S100A1 in renal oncocytoma, oncocytic papillary renal cell carcinoma, and two variants of chromophobe renal cell carcinoma. (21717314)
2011
3
Successful one stage operation for a synchronous, duodenal carcinoma, colonic carcinoma and renal oncocytoma in an adult patient. (21884600)
2011
4
Incidental giant renal oncocytoma: a case report. (21059248)
2010
5
Expression analysis of Wnt-5a in renal epithelial neoplasms: distinguishing renal oncocytoma from a wide spectrum of renal cell carcinomas. (20572590)
2010
6
Giant renal oncocytoma: a case report and review of the literature. (20205900)
2010
7
Editorial comment from Dr Picken to Molecular pathology of renal oncocytoma: a review. (20590946)
2010
8
Gene expression profiling of chromophobe renal cell carcinomas and renal oncocytomas by Affymetrix GeneChip using pooled and individual tumours. (19680475)
2009
9
Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma. (18799195)
2009
10
SDHB-associated renal oncocytoma suggests a broadening of the renal phenotype in hereditary paragangliomatosis. (19184535)
2009
11
Breast carcinoma metastatic to renal oncocytoma detected on F-18-FDG PET/CT. (19387207)
2009
12
Asymptomatic giant renal oncocytoma presenting with hypertension. (18985529)
2008
13
Renal oncocytoma with bilateral synchronous renal cell carcinoma in a patient undergoing long-term hemodialysis. (18184181)
2008
14
Progesterone receptor reactivity in renal oncocytoma and chromophobe renal cell carcinoma. (18081814)
2008
15
Somatic pairing of chromosome 19 in renal oncocytoma is associated with deregulated EGLN2-mediated [corrected] oxygen-sensing response. (18773095)
2008
16
Metastatic renal oncocytoma. (17557872)
2007
17
Claudin-7 is highly expressed in chromophobe renal cell carcinoma and renal oncocytoma. (17449941)
2007
18
Renal oncocytoma associated with necrotizing glomerulonephritis. (16538978)
2006
19
Expression of kidney-specific cadherin in chromophobe renal cell carcinoma and renal oncocytoma. (16753598)
2006
20
Immunophenotypic comparison of salivary gland oncocytoma and metastatic renal cell carcinoma. (15933529)
2005
21
Multifocal renal oncocytoma in a patient with Von Hippel-Lindau mutation. (16360474)
2005
22
Expression of CD3 antigens in renal tubule epithelium and renal oncocytomas. (16308105)
2005
23
A metachronous, atypical, multifocal renal oncocytoma with a concomitant renal cell carcinoma of the contralateral side and bilateral multifocal oncocytomas: two case reports and review of literature. (16075151)
2005
24
Follow-up of renal oncocytoma diagnosed by percutaneous tumor biopsy. (16360437)
2005
25
Renal oncocytoma with loss of chromosomes Y and 1 evolving to papillary carcinoma in connection with gain of chromosome 7. Coincidence or progression? (16271962)
2005
26
Overexpression of KIT (CD117) in chromophobe renal cell carcinoma and renal oncocytoma. (15198361)
2004
27
Small renal oncocytoma with central cystic degeneration. (14706015)
2004
28
Keratin immunohistochemistry in renal cell carcinoma subtypes and renal oncocytomas: a systematic analysis of 233 tumors. (14727107)
2004
29
Bilateral multifocal renal oncocytoma. (14579138)
2003
30
Reversible migratory osteoporosis in renal oncocytoma mimicking renal cell carcinoma with bone metastases. (12607593)
2002
31
Organ sparing surgery for giant bilateral renal oncocytoma. (12441959)
2002
32
Paxillin: application of immunohistochemistry to the diagnosis of chromophobe renal cell carcinoma and oncocytoma. (11759057)
2001
33
Atypical chromosome abnormalities in a renal oncocytoma. (10459358)
1999
34
Coexisting non-functioning pheochromocytoma and renal oncocytoma: a case report and review of the literature. (8886727)
1996
35
Renal adenoma and oncocytoma. (8595549)
1995
36
Bilateral renal oncocytoma: case report and implications in renal tumour management. (7887869)
1995
37
Renal oncocytoma in transplant patients: report of 2 cases. (7838263)
1994
38
Unusual presentation of renal oncocytoma. (1413356)
1992
39
Renal oncocytoma and granular renal cell carcinoma. A comparative clinicopathologic and DNA flow cytometric study. (1462956)
1992
40
Inadequate documentation of apparent renal oncocytoma with metastases. (3347982)
1988
41
Uptake of 99mTc-DTPA by a renal oncocytoma. (3311767)
1987
42
Renal oncocytoma. (3727238)
1986
43
Scar sign of renal oncocytoma: magnetic resonance imaging appearance and lack of specificity. (3523935)
1986
44
Multiple renal oncocytoma and bilateral cystic kidney. (4076258)
1985
45
Renal oncocytoma followed for eighteen years without resection. (3901483)
1985
46
Morphologic features of renal oncocytoma: a light and electron microscopic study. (6490001)
1984
47
Renal oncocytoma. (6517794)
1984
48
Renal oncocytoma: the incidence of 18 surgical and 12 autopsy cases. (6519647)
1984
49
A case of the month No. 55. Renal oncocytoma; focal nodular hyperplasia of the liver. (7103765)
1982
50
Renal oncocytoma. Further diagnostic observations. (7449602)
1980

Genetic Variations for Renal Oncocytoma

Expression for genes affiliated with Renal Oncocytoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Renal Oncocytoma

Search GEO for disease gene expression data for Renal Oncocytoma.

Pathways for genes affiliated with Renal Oncocytoma

Sources:
12EMD Millipore, 54Reactome
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Pathways related to Renal Oncocytoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1KRT7, KRT14, VIM
2
Hide members
10.1KRT14, CLDN7, CLDN8

Compounds for genes affiliated with Renal Oncocytoma

Sources:
45Novoseek, 24HMDB
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Compounds related to Renal Oncocytoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1reticulin4510.3KRT7, VIM
22-methoxyethanol4510.2KRT14, S100A1, VIM
3mucicarmine4510.2VIM, S100A1, KRT14, KRT7
4hematoxylin4510.1VIM, S100A1, KRT14, KRT7
5b 7234510.0KRT7, S100A1, VIM
6toluidine459.9S100A1, VIM
7paraffin459.9VIM, PVALB, S100A1, MAGEA3, KRT14, KRT7
8iron45 2410.8KRT7, KRT14, EGLN2, S100A1, PVALB, VIM

GO Terms for genes affiliated with Renal Oncocytoma

Sources:
16Gene Ontology
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Cellular components related to Renal Oncocytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00588210.1KRT7, KRT14, VIM

Products for genes affiliated with Renal Oncocytoma

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  • Proteins
  • Lysates
  • Antibodies

Sources for Renal Oncocytoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet