MCID: RNL007
MIFTS: 50

Renal Tubular Acidosis malady

Categories: Rare diseases, Nephrological diseases
Genes Tissues Related diseases Publications Pathways Drugs

Aliases & Classifications for Renal Tubular Acidosis

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Aliases & Descriptions for Renal Tubular Acidosis:

Name: Renal Tubular Acidosis 35 11 48 27 13 68
Acidosis, Renal Tubular 39
 
Acidosis Renal Tubular 50

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Nephrological diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology11 DOID:14219
ICD1030 N25.89
SNOMED-CT62 1776003
MeSH39 D000141
NCIt45 C28129

Summaries for Renal Tubular Acidosis

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Disease Ontology:11 A renal tubular transport disease characterized by excess levels of acid in the blood, due to a failure of the kidneys to appropriately acidify the urine.

MalaCards based summary: Renal Tubular Acidosis, also known as acidosis, renal tubular, is related to renal tubular acidosis with deafness and proximal renal tubular acidosis. An important gene associated with Renal Tubular Acidosis is ATP6V1B1 (ATPase H+ Transporting V1 Subunit B1), and among its related pathways are Erythrocytes take up carbon dioxide and release oxygen and Proximal tubule bicarbonate reclamation. The drugs citric acid monohydrate and citrus naringinine have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and thyroid, and related mouse phenotypes are growth/size/body region and mortality/aging.

Wikipedia:71 Renal tubular acidosis (RTA) is a medical condition that involves an accumulation of acid in the body... more...

Related Diseases for Renal Tubular Acidosis

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Diseases related to Renal Tubular Acidosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 149)
idRelated DiseaseScoreTop Affiliating Genes
1renal tubular acidosis with deafness12.6
2proximal renal tubular acidosis12.5
3renal tubular acidosis, distal, ar12.5
4renal tubular acidosis, distal, autosomal recessive12.5
5renal tubular acidosis, distal, ad12.5
6renal tubular acidosis, proximal, with ocular abnormalities12.4
7osteopetrosis, autosomal recessive 3, with renal tubular acidosis12.4
8slc4a1-associated distal renal tubular acidosis12.4
9renal tubular acidosis, distal12.4
10renal tubular acidosis, distal, type 312.1
11neuroaxonal dystrophy renal tubular acidosis12.1
12renal tubular acidosis, distal, type 412.0
13autosomal dominant proximal renal tubular acidosis12.0
14nephrocalcinosis11.5
15lowe syndrome11.1
16osteopetrosis, autosomal recessive 110.9
17dent disease 210.9
18osteopetrosis10.3
19osteomalacia10.3
20diabetes insipidus10.3
21systemic lupus erythematosus10.2
22primary biliary cirrhosis10.2
23sjogren's syndrome10.2
24lupus erythematosus10.2
25meigel disease10.2ATP6V0A4, ATP6V1B1
26sensorineural hearing loss10.2
27fanconi syndrome10.2
28cerebritis10.2
29medullary sponge kidney10.2
30hyperparathyroidism10.2
31hypothyroidism10.2
32cataract 38, autosomal recessive10.1ATP6V0A4, ATP6V1B1, SLC4A1
33nephrolithiasis10.1
34myopathy, lactic acidosis, and sideroblastic anemia 210.1SLC4A4, SLC9A3
35metabolic acidosis10.1
36respiratory failure10.1
37thyroiditis10.1
38mednik syndrome10.1SLC26A6, SLC9A3
39osteoporosis10.0
40hypokalemia10.0
41hyperthyroidism10.0
42hyperammonemia10.0
43retinal cone dystrophy 110.0ATP6V0A4, ATP6V1B1, CA2, SLC4A1
44arthritis10.0
45hemolytic anemia10.0
46hepatitis10.0
47rickets10.0
48cystinosis10.0
49hereditary spherocytosis10.0
50bartter syndrome, type 310.0ATP6V0A4, REN

Graphical network of the top 20 diseases related to Renal Tubular Acidosis:



Diseases related to renal tubular acidosis

Symptoms & Phenotypes for Renal Tubular Acidosis

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MGI Mouse Phenotypes related to Renal Tubular Acidosis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053787.7ATP6V0A4, CA2, NR3C2, OCRL, REN, SLC4A1
2MP:00107687.2ATP6V0A4, CA2, NR3C2, OCRL, REN, SLC4A1
3MP:00053676.1ATP6V0A4, ATP6V1B1, CA2, NR3C2, OCRL, REN
4MP:00053766.0ATP6V0A4, ATP6V1B1, CA2, NR3C2, OCRL, REN

Drugs & Therapeutics for Renal Tubular Acidosis

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Drugs for Renal Tubular Acidosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 36)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Miconazoleapproved, investigational, vet_approvedPhase 4370622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
2
SpironolactoneapprovedPhase 42321952-01-7, 52-01-75833
Synonyms:
4-18-00-01601 (Beilstein Handbook Reference)
4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate
496916-40-6
52-01-7
7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
AB00513806
AC-4214
AC1L1L8Q
Abbolactone
Acelat
Aldace
Aldactazide
Aldactide
Aldactone
Aldactone (TN)
Aldactone A
Alderon
Aldopur
Almatol
Alphapharm Brand of Spironolactone
Alpharma Brand of Spironolactone
Alter Brand of Spironolactone
Altex
Aquareduct
Ashbourne Brand of Spironolactone
Azupharma Brand of Spironolactone
BIDD:PXR0071
BPBio1_000194
BRD-K90027355-001-03-4
BRN 0057767
BSPBio_000176
C07310
C24H32O4S
CHEBI:428201
CHEBI:45692
CHEBI:9241
CHEMBL1393
CID5833
CPD000471892
Cardel Brand of Spironolactone
D00443
D013148
DB00421
Deverol
Dexo Brand of Spironolactone
Diatensec
Dira
Duraspiron
EINECS 200-133-6
Espironolactona
Espironolactona Alter
Espironolactona Mundogen
Espironolactona [INN-Spanish]
Euteberol
Flumach
Frumikal
Generosan Brand of Spironolactone
HMS1568I18
HMS2090N21
HSDB 3184
Hormosan Brand of Spironolactone
I06-1970
Jenapharm Brand of Spironolactone
Jenaspiron
LS-118614
LT00772287
Lacalmin
Lacdene
Laractone
MLS001074672
MLS001333253
MLS001333254
MLS002153245
MLS002207058
Mayoly-Spindler Brand of Spironolactone
Melarcon
Merck dura Brand of Spironolactone
Mundogen Brand of Spironolactone
NCGC00164397-01
 
NCGC00164397-02
NSC 150399
NSC150399
Nefurofan
Novo Spiroton
Novo-Spiroton
NovoSpiroton
Novopharm Brand of Spironolactone
Osyrol
Pfizer Brand of Spironolactone
Pharmafrid Brand of Spironolactone
Practon
Prestwick0_000128
Prestwick1_000128
Prestwick2_000128
Prestwick3_000128
Roche Brand of Spironolactone
S0260
S3378_SIGMA
SAM002264648
SC 9420
SC-9420
SC9420
SMR000471892
SNL
SPBio_002115
Sagisal
Searle Brand of Spironolactone
Sincomen
Spiractin
Spiresis
Spiretic
Spiridon
Spiro L.U.T.
Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan)
Spiro-Tablinen
Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]
Spirobeta
Spiroctan
Spiroctanie
Spiroderm
Spirogamma
Spirolactone
Spirolakton
Spirolang
Spirolone
Spirone
Spirono Isis
Spirono-Isis
Spironocompren
Spironolactone
Spironolactone (JP15/USP/INN)
Spironolactone A
Spironolactone [BAN:INN:JAN]
Spironolactone [INN:BAN:JAN]
Spironolactonum
Spironolactonum [INN-Latin]
Spironolattone
Spironolattone [DCIT]
Spironone
Spirospare
Sprioderm
Supra-puren
Suracton
UNII-27O7W4T232
Uractone
Urusonin
Veroshpiron
Verospiron
Verospirone
Verospirone Opianin
WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ
Worwag Brand of Spironolactone
Xenalon
ZINC03861599
betapharm Brand of Spironolactone
ct Arzneimittel Brand of Spironolactone
ct-Arzneimittel Brand of Spironolactone
spiro von ct
spironolactone
spironolattone
von ct, spiro
3
Amphotericin Bapproved, investigationalPhase 41211397-89-314956, 5280965
Synonyms:
12633-72-6
1397-89-3
30782-62-8
5-18-10-00525 (Beilstein Handbook Reference)
54482-28-9
8055-20-7
AB00513832
ABLC
AC1L1CN2
AC1L24V6
AC1L70KF
AC1L73U6
AC1NQXTD
AC1NTQ32
AC1NUQG4
AC1NY9JC
AC1O7GCZ
AC1O8FQV
AC1O8PFK
AI3-26528
AMPH-B
AMPH-b
Abelcet
Abelecet
AmBisome (TN)
Ambap1397-89-3
Ambisome
Amfotericina B
Amfotericina B [INN-Spanish]
Ampho-Moronal
Amphocin
Amphomoronal
Amphortericin B
Amphotec
Amphotec (TN)
Amphotericin
Amphotericin .BETA.
Amphotericin B
Amphotericin B (JP15/USP/INN)
Amphotericin B Cholesterol Dispersion
Amphotericin B Colloidal Dispersion
Amphotericin B [USAN:INN:JAN]
Amphotericin B, Lipid-based
Amphotericin B, Streptomyces sp.
Amphotericin-B
Amphotericine B
Amphotericine B [INN-French]
Amphotericinum
Amphotericinum B
Amphotericinum B [INN-Latin]
Amphotherizin
Amphotherizin [German]
Amphotéricine B
Amphozone
BIDD:GT0351
BPBio1_000374
BRN 0078342
BSPBio_000340
C-AmB
C06573
C47H73NO17
CCRIS 5963
CHEBI:2682
CHEMBL1200646
CHEMBL267345
CID10533925
CID10629638
CID10677275
CID14956
CID1972
 
CID352546
CID354192
CID5280965
CID5386092
CID5458486
CID5771695
CID6604295
CID6708817
CID6713692
CID9919339
D00203
DB00681
DivK1c_007045
EINECS 215-742-2
Fungilin
Fungisome
Fungisone
Fungizone
Fungizone (TN)
HMS1569A22
HSDB 3008
HSDB 3008 IAB
Halizon
I06-0257
KBio1_001989
KBio2_000551
KBio2_003119
KBio2_005687
KBioGR_002298
KBioSS_000551
LMPK06000002
LNS-AmB
LS-187721
LS-93
Liposomal Amphotericin B
Liposomal amphotericin b
MLS002702966
MolPort-006-392-260
Mysteclin-F
NCGC00014913
NCGC00090808-01
NCGC00098014-01
NCGC00179595-01
NCI527017
NCI60_004288
NCIStruc1_001042
NCIStruc2_000920
NKTR-024
NS 718
NSC 527017
NSC-527017
NSC527017
Prestwick0_000410
Prestwick1_000410
Prestwick2_000410
Prestwick3_000410
Prestwick_721
SMP1_000302
SMR001566780
SPBio_000715
SPBio_002279
ST50999656
SinuNase
SpecPlus_000949
Spectrum2_000818
Spectrum4_001779
Spectrum_000111
UNII-7XU7A7DROE
amophotericin B
amphotericin B liposomal
amphotericin b
4Natriuretic AgentsPhase 41697
5diureticsPhase 41418
6Liposomal amphotericin BPhase 4121
7MineralocorticoidsPhase 4367
8Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 413168
9Mineralocorticoid Receptor AntagonistsPhase 4346
10Hormone AntagonistsPhase 413180
11Anti-Infective AgentsPhase 422062
12Antifungal AgentsPhase 43696
13Anti-Bacterial AgentsPhase 411226
14Antiparasitic AgentsPhase 42199
15Antiprotozoal AgentsPhase 42051
16HormonesPhase 414415
17Diuretics, Potassium SparingPhase 41917
18Calcium, DietaryPhase 2, Phase 35713
19Bone Density Conservation AgentsPhase 2, Phase 33376
20
Acetazolamideapproved, vet_approved8059-66-51986
Synonyms:
1424-27-7 (mono-hydrochloride salt)
1yda
1ydb
1ydd
1zsb
2-acetylamino-1,3,4-thiadiazole-5-sulfonamide
2h4n
3czv
4-Diamox
5-acetamido-1,3,4-thiadiazole-2-sulfonamide
5-acetylamino-1,3,4-thiadiazole-2-sulfonamide
5661-25-6
59-66-5
8017-69-4
A 6011
A6011_SIAL
A6011_SIGMA
AB00051906
AC-12779
AC1L1CO5
AI3-52458
AKOS000715163
Acetadiazol
Acetamidothiadiazolesulfonamide
Acetamox
Acetazolam
Acetazolamid
Acetazolamida
Acetazolamida [INN-Spanish]
Acetazolamide (AAZ)
Acetazolamide (JP15/USP/INN)
Acetazolamide Apotex Brand
Acetazolamide Chiesi Brand
Acetazolamide Dioptic Brand
Acetazolamide Grin Brand
Acetazolamide ICN Brand
Acetazolamide Jumer Brand
Acetazolamide Llorens Brand
Acetazolamide Medphano Brand
Acetazolamide Novopharm Brand
Acetazolamide Orion Brand
Acetazolamide Sodium
Acetazolamide Sodium, (Sterile)
Acetazolamide Wassermann Brand
Acetazolamide [INN:BAN:JAN]
Acetazolamide, Monosodium Salt
Acetazolamidum
Acetazolamidum [INN-Latin]
Acetazolamine
Acetazoleamide
Acetozalamide
Acétazolamide
Ak Zol
Ak-Zol
AkZol
Apo Acetazolamide
Apo-Acetazolamide
ApoAcetazolamide
Apotex Brand of Acetazolamide
Atenezol
BAS 01585728
BIDD:GT0643
BPBio1_000007
BSPBio_000005
BSPBio_001788
C06805
C4H6N4O3S2
CAS-59-66-5
CCRIS 5811
CHEBI:27690
CHEMBL20
CID1986
CPD0-1626
CPD000058394
Carbonic Anhydrase Inhibitor 6063
Carbonic Anhydrase Inhibitor No. 6063
Carbonic anhydrase inhibitor 6063
Chiesi Brand of Acetazolamide
Ciba Vision Brand of Acetazolamide
Cidamex
D000086
D00218
DB00819
Dazamide
Defiltran
Dehydratin
Diacarb
Diakarb
Diamox
Diamox (TN)
Diamox Sequels
Didoc
Diluran
 
Dioptic Brand of Acetazolamide
Diuramid
Diuramide
Diureticum-Holzinger
Diureticum-holzinger
Diuriwas
Diutazol
DivK1c_000017
Donmox
Duiramid
EINECS 200-440-5
EU-0100039
Edemox
Eumicton
Fonurit
Glauconox
Glaumox
Glaupax
Glupax
Grin Brand of Acetazolamide
HMS1568A07
HMS1920A05
HMS2091G05
HMS500A19
HSDB 3002
Huma Zolamide
Huma-Zolamide
HumaZolamide
I09-0425
ICN Brand of Acetazolamide
IDI1_000017
Jumer Brand of Acetazolamide
KBio1_000017
KBio2_000358
KBio2_002926
KBio2_005494
KBio3_001288
KBioGR_000558
KBioSS_000358
LS-10227
Llorens Brand of Acetazolamide
Lopac-A-6011
Lopac0_000039
MLS000028435
MLS001148438
Medphano Brand of Acetazolamide
MolPort-001-783-578
Monosodium Salt Acetazolamide
N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide
N-[5-(aminosulfonyl)-1,3,5-thiadiazol-2-yl]acetamide
NCGC00015074-01
NCGC00015074-02
NCGC00015074-03
NCGC00015074-06
NCGC00015074-11
NCGC00023455-03
NCGC00023455-04
NCGC00023455-05
NCGC00023455-06
NCGC00023455-07
NINDS_000017
NSC 145177
NSC145177
Natrionex
Nephramid
Nephramide
Novopharm Brand of Acetazolamide
Orion Brand of Acetazolamide
Phonurit
Prestwick0_000003
Prestwick1_000003
Prestwick2_000003
Prestwick3_000003
Prestwick_4
SAM002554883
SBB056640
SK-acetazolamide
SMR000058394
SPBio_000004
SPBio_001926
SPECTRUM1500102
Sk-Acetazolamide
Spectrum2_000082
Spectrum3_000284
Spectrum4_000139
Spectrum5_000738
Spectrum_000018
Storz Brand of Acetazolamide Preparation
Storzolamide
UNII-O3FX965V0I
Vetamox
WLN: T5NN DSJ CSZW EMV1
Wassermann Brand of Acetazolamide
Wyeth Brand of Acetazolamide Preparation
acetazolamide
21
Potassium Citrateapproved, vet_approved27
Synonyms:
 
tripotassium citrate
22
Furosemideapproved, vet_approved19354-31-93440
Synonyms:
2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid
4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid
4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid
4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid
4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
41733-55-5 (mono-hydrochloride salt)
5-18-09-00555 (Beilstein Handbook Reference)
54-31-9
AB00052001
AC-11067
AC1L1FXW
AC1Q557O
AKOS000266625
ARONIS24304
Acetic acid potassium salt
Aisemide
Aldalix
Aldic
Aluzine
Anfuramaide
Apo-Frusemide
Apo-Furosemide
Aquarid
Aquasin
Arasemide
BIDD:GT0139
BPBio1_000443
BRD-K78010432-001-05-8
BRN 0840915
BSPBio_000401
BSPBio_002054
Beronald
Bio-0044
Bioretic
Bristab
Bristurin
C12H11ClN2O5S
CAS-54-31-9
CCRIS 1951
CHEBI:47426
CHEMBL35
CID3440
CPD000058202
Cetasix
Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure
Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure [German]
D00331
D005665
DB00695
DB07799
Depix
Desal
Desdemin
Di-Ademil
Dihydroflumethiazide
Dirine
Disal
Discoid
Disemide
Diucardin
Diumide-K
Diural
Diurapid
Diuretic Salt
Diuretic salt
Diurin
Diurolasa
Diusemide
Diusil
Diuzol
DivK1c_000575
Dranex
Dryptal
Durafurid
EINECS 200-203-6
Edemid
Edenol
Eliur
Elodrine
Endural
Errolon
Eutensin
F0182
F4381_SIGMA
FUN
FUROSEMIDE USP
Farsix
Finuret
Fluidrol
Fluss
Franyl
Frumex
Frumide
Frumil
Frusedan
Frusema
Frusemid
Frusemide
Frusemin
Frusenex
Frusetic
Frusid
Fu sid
Fulsix
Fuluvamide
Fuluvamine
Furanthril
Furanthryl
Furantral
Furantril
Furanturil
Furesis
Furetic
Furex
Furfan
Furix
Furmid
Furo-Basan
Furo-Puren
Furo-puren
Furobeta
Furocot
Furodiurol
Furodrix
Furomen
Furomex
Furomide M.D
Furomide M.D.
Furorese
Furosan
Furose
Furosedon
Furosemid
Furosemida
Furosemida [INN-Spanish]
Furosemide
Furosemide "mita"
Furosemide (JP15/USP/INN)
Furosemide Monohydrochloride
Furosemide Monosodium Salt
Furosemide [USAN:INN:JAN]
Furosemidu
Furosemidu [Polish]
Furosemidum
Furosemidum [INN-Latin]
Furosemix
Furoside
Furosifar
Furosix
Furoter
Furovite
Fursemid
Fursemida
Fursemide
Fursol
Fusid
Fusidic acid
 
Golan
HMS1569E03
HMS1920B03
HMS2090K06
HMS2091H05
HMS501M17
HSDB 3086
Hissuflux
Hoe-058A
Hydol
Hydrenox
Hydrex
Hydro
Hydro-Rapid
Hydro-rapid
Hydroled
I04-0179
IDI1_000575
Impugan
Jenafusid
KBio1_000575
KBio2_001580
KBio2_004148
KBio2_006716
KBio3_001274
KBioGR_001259
KBioSS_001580
Katlex
Kofuzon
Kolkin
Kutrix
LB 502
LB-502
LS-204
Lasemid
Lasex
Lasiletten
Lasilix
Lasix
Lasix (TN)
Lasix (tn)
Lasix Retard
Lasix Special
Lasix, Frusemide, Furosemide
Laxur
Lazix
Leodrine
Less Diur
Liside
Logirene
Lowpston
Lowpstron
Luscek
MLS001066374
MLS001306403
Macasirool
Marsemide
Metflorylthiazidine
Methforylthiazidine
Mirfat
Mita
Moilarorin
MolPort-001-641-065
Myrosemide
NCGC00016241-01
NCGC00090893-01
NCGC00090893-02
NCGC00090893-03
NCGC00090893-05
NCGC00090893-06
NCI-C55936
NINDS_000575
NSC 269420
NSC269420
Nadis
Nelsix
Neo-Renal
Neo-renal
Nephron
Nicorol
Novosemide
Octan Draselny
Octan draselny
Odemase
Odemex
Oedemex
Olmagran
Oprea1_667724
Osyrol
Polysquall A
Prefemin
Prestwick0_000341
Prestwick1_000341
Prestwick2_000341
Prestwick3_000341
Prestwick_752
Profemin
Promedes
Promide
Protargen
Puresis
Radisemide
Radonna
Radouna
Retep
Rodiuran
Rontyl
Rosemide
Rosis
Rusyde
S1603_Selleck
SAM002264614
SMP1_000129
SMR000058202
SPBio_001129
SPBio_002322
SPECTRUM1500310
STK177334
Sal Diureticum
Sal diureticum
Salinex
Salix
Salix (brand of furosemide)
Salurex
Salurid
Saluron
Seguril
Selectofur
Sigasalur
Sisuril
Spectrum2_001005
Spectrum3_000437
Spectrum4_000560
Spectrum5_000744
Spectrum_001100
Spirofur
Synephron
TL8003563
Transit
Trofurit
UNII-7LXU5N7ZO5
UPCMLD-DP022
UPCMLD-DP022:001
Uremide
Uresix
Urex
Urex-M
Urian
Uridon
Uritol
Urosemide
Vergonil
Vesix
WLN: T5OJ B1MR CG FVQ DSZW
Yidoli
Zafimida
fulvamide
furosemide
furosemide ''mita''
less Diur
23
Fludrocortisoneapproved27127-31-131378
Synonyms:
(11beta)-9-Fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione
(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
127-31-1
4-08-00-03427 (Beilstein Handbook Reference)
9 .alpha. FF
9 Fluoro 17 Hydroxycortisone
9 Fluorocortisol
9 Fluorohydrocortisone
9 alpha FF
9 alpha Fludrohydrocortisone
9 alpha Fluoro 17 Hydroxycorticosterone
9 alpha Fluorohydrocortisone
9 alpha-Fludrocortisone
9 alpha-Fluoro-17-Hydroxycorticosterone
9 alpha-Fluorocortisol
9 alpha-Fluorohydrocortisone
9-AF
9-AFH
9-Fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione
9-Fluoro-11.beta.,17,21-trihydroxypregn-4-ene-3,20-dione
9-Fluoro-11beta,17,21-trihydroxypregn-4-ene-3,20-dione
9-Fluoro-17-Hydroxycortisone
9-Fluorocortisol
9-Fluorohydrocortisone
9-alpha-Fludrocortisone
9-alpha-Fluoro-17-hydroxycorticosterone
9-alpha-Fluorocortisol
9-alpha-Fluorohydrocortisone
9.alpha.-Fluoro-11.beta.,17.alpha.,21-trihydroxy-4-pregnene-3,20-dione
9.alpha.-Fluoro-17-hydroxycorticosterone
9.alpha.-Fluorocortisol
9.alpha.-Fluorohydrocortisone
9alpha-FLUOROCORTISOL
9alpha-Fludrocortisone
9alpha-Fluoro-11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione
9alpha-Fluoro-17-hydroxycorticosterone
9alpha-Fluoro-hydrocortisone
9alpha-Fluorocortisol
AC1L1LI8
AC1Q5HJH
Alflorone
Astonin
Astonin H
Astonin Merck
Astonin-H
Astonin-H (TN)
BRN 3014278
 
C07004
C21H29FO5
CHEBI:50885
CHEMBL1201388
CID31378
D005438
D07967
DB00687
DB02478
EINECS 204-833-2
F-COL
F-Cortef
FCOL
Florinef
Fludrocortison
Fludrocortisona
Fludrocortisona [INN-Spanish]
Fludrocortisone
Fludrocortisone (INN)
Fludrocortisone [INN:BAN]
Fludrocortisonum
Fludrocortisonum [INN-Latin]
Fludrocortone
Fludrone
Fludronef
Fluodrocortisone
Fluohydrisone
Fluohydrocortisone
Fluorocortisol
Fluorocortisone
HSDB 3332
Hydrocortisone-9alpha-fluoro
LMST02030103
LS-118690
Merck Brand of Fludrocortisone
Merck, Astonin
MolPort-005-943-437
NCGC00181081-01
NSC 11318
NSC11318
Pregn-4-ene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy- (8CI)
Prestwick_648
StC 1400
U 5963
UNII-U0476M545B
WLN: L E5 B666 OV MUTJ A1 BF CQ E1 FV1Q FQ
ZINC04097304
ZK5
fludrocortisone
24Anticoagulants2623
25Anticonvulsants2695
26Expectorants404
27Respiratory System Agents4997
28Chelating Agents1423
29Carbonic Anhydrase Inhibitors186
30Anti-Inflammatory Agents10729
31Sodium Potassium Chloride Symporter Inhibitors181
32Immunoglobulins6394
33calcitonin107
34Antibodies6394
35CitrateNutraceutical1160
36
Citric Acidnutraceutical, vet_approved116077-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid

Interventional clinical trials:

(show all 11)
idNameStatusNCT IDPhase
1Use of Spironolactone for the Prevention of Electrolyte Abnormalities in Patients Treated With Amphotericin BTerminatedNCT01843309Phase 4
2Low Salt Diet in Idiopathic HypercalciuriaCompletedNCT01005082Phase 2, Phase 3
3Renal Tubular Acidosis in Incident Renal Transplant RecipientsUnknown statusNCT01283880
4Renal Tubular Acidosis is Highly Prevalent in Critically Ill PatientsCompletedNCT02392091
5A Study Of Mircera In Patients With Kidney Disease Who Are Not On DialysisCompletedNCT02490514
6Metabolic Consequences of Heterozygous Hereditary Fructose IntoleranceCompletedNCT02979106
7Effects of Potassium Citrate in Urine of Children With Elevated Calcium in Urine and Kidney StonesCompletedNCT00120731
8Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular AcidosisRecruitingNCT01690039
9Genetic and Morphological Analysis of Thyrotoxic Periodic ParalysisActive, not recruitingNCT02287363
10Diabetic Kidney Alarm (DKA) StudyNot yet recruitingNCT03128229
11Genetic Study of Nephrolithiasis in Gouty DiathesisTerminatedNCT00149305

Search NIH Clinical Center for Renal Tubular Acidosis

Inferred drug relations via UMLS68/NDF-RT46:

Show with subtypes


Cochrane evidence based reviews: acidosis, renal tubular

Genetic Tests for Renal Tubular Acidosis

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Genetic tests related to Renal Tubular Acidosis:

id Genetic test Affiliating Genes
1 Renal Tubular Acidosis27

Anatomical Context for Renal Tubular Acidosis

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MalaCards organs/tissues related to Renal Tubular Acidosis:

36
Kidney, Bone, Thyroid, Liver, Testes, Colon, Brain

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Renal Tubular Acidosis:
id TissueAnatomical CompartmentCell Relevance
1 KidneyProximal TubuleProximal Tubule Cells Potential therapeutic candidate, affected by disease

Publications for Renal Tubular Acidosis

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Articles related to Renal Tubular Acidosis:

(show top 50)    (show all 644)
idTitleAuthorsYear
1
Renal tubular acidosis. (28092281)
2017
2
Clinical analysis of hyperkalemic renal tubular acidosis caused by calcineurin inhibitors in solid organ transplant recipients. (27966241)
2017
3
Successful treatment of proximal renal tubular acidosis and Fanconi syndrome with vitamin D replacement. (27424705)
2016
4
Distal Renal Tubular Acidosis Associated with Celiac Disease and Thyroiditis. (27889732)
2016
5
Autosomal dominant osteopetrosis associated with renal tubular acidosis is due to a CLCN7 mutation. (27540713)
2016
6
A case of multiple myeloma presenting as a distal renal tubular acidosis with extensive bilateral nephrolithiasis. (26998308)
2016
7
Complicated pregnancies in inherited distal renal tubular acidosis: importance of acid-base balance. (28005240)
2016
8
Anesthetic Management of a Surgical Patient with Chronic Renal Tubular Acidosis Complicated by Subclinical Hypothyroidism. (27648310)
2016
9
Renal tubular acidosis type 4 in pregnancy. (26989116)
2016
10
A novel mutant Na(+) /HCO3(-) cotransporter NBCe1 in a case of compound-heterozygous inheritance of proximal renal tubular acidosis. (27338124)
2016
11
Selective screening for distal renal tubular acidosis in recurrent kidney stone formers: initial experience and comparison of the simultaneous furosemide and fludrocortisone test with the short ammonium chloride test. (26961999)
2016
12
Bilateral Nephrocalcinosis in Primary Distal Renal Tubular Acidosis. (27090423)
2016
13
Pathophysiology of Renal Tubular Acidosis: Core CurriculumA 2016. (27188519)
2016
14
Mutations in ATP6V1B1 and ATP6V0A4 genes cause recessive distal renal tubular acidosis in Mexican families. (27247958)
2016
15
Successful treatment of renal tubular acidosis and recurrent secondary struvite kidney stones with rituximab in a patient with primary SjAPgren's syndrome. (28031439)
2016
16
Systemic lupus erythematosus and renal tubular acidosis associated with hyperthyroidism. Case Report. (27179580)
2016
17
Hypokalemic Paralysis in Sjogren's Syndrome Secondary to Renal Tubular Acidosis. (27731561)
2016
18
Case report of renal tubular acidosis and misdiagnosed. (26857205)
2016
19
Late Metabolic Acidosis Caused by Renal Tubular Acidosis in Acute Salicylate Poisoning. (27181539)
2016
20
Sodium valproate-induced Fanconi type proximal renal tubular acidosis. (26823359)
2016
21
Primary sclerosing cholangitis: a new cause of distal renal tubular acidosis. (27994859)
2016
22
Distal renal tubular acidosis without renal impairment after use of tenofovir: a case report. (27866471)
2016
23
Review of the Diagnostic Evaluation of Renal Tubular Acidosis. (27999512)
2016
24
A novel heterozygous mutation in the ATP6V0A4 gene encoding the V-ATPase a4 subunit in an adult patient with incomplete distal renal tubular acidosis. (27274828)
2016
25
Failure to thrive and nephrocalcinosis due to distal renal tubular acidosis: A rare presentation of pediatric lupus nephritis. (27900972)
2016
26
Clinical and molecular findings in three Moroccan families with distal renal tubular acidosis and deafness: Report of a novel mutation of ATP6V1B1 gene. (27140593)
2016
27
Erratum: A novel heterozygous mutation in the ATP6V0A4 gene encoding the V-ATPase a4 subunit in an adult patient with incomplete distal renal tubular acidosis. (27994869)
2016
28
Sjogren's syndrome presenting as Hypokalemic paralysis due to distal renal tubular acidosis. (27728182)
2016
29
Bone Mineral Density in SjAPgren Syndrome Patients with and Without Distal Renal Tubular Acidosis. (26873478)
2016
30
A single nucleotide polymorphism in kidney anion exchanger 1 gene is associated with incomplete type 1 renal tubular acidosis. (27767102)
2016
31
The need for genetic study to diagnose some cases of distal renal tubular acidosis. (27493007)
2016
32
Transient distal renal tubular acidosis following hump nosed viper bite: Two cases from Sri Lanka. (27752013)
2016
33
Type 4 renal tubular acidosis in a kidney transplant recipient. (27105603)
2016
34
Band 3 null(VIENNA) , a novel homozygous SLC4A1 p.Ser477X variant causing severe hemolytic anemia, dyserythropoiesis and complete distal renal tubular acidosis. (27718309)
2016
35
Distal Renal Tubular Acidosis Screening by Urinary Acidification Testing in Mexican Children. (26202743)
2015
36
Hypokalemic paralysis as a primary presentation of Fanconi's syndrome and distal renal tubular acidosis in a patient with primary Sjogren's syndrome. (26053828)
2015
37
Renal tubular acidosis type IV as a complication of lupus nephritis. (26345674)
2015
38
Mutations in exons 3 and 7 resulting in truncated expression of human ATP6V1B1 gene showing structural variations contributing to poor substrate binding-causative reason for distal renal tubular acidosis with sensorineural deafness. (25517796)
2015
39
Comprehensive clinical approach to renal tubular acidosis. (25951806)
2015
40
Hypokalemia and suspected renal tubular acidosis associated with topical carbonic anhydrase inhibitor therapy in a cat. (26595765)
2015
41
Renal tubular acidosis complicated with hyponatremia due to cortisol insufficiency. (26609420)
2015
42
Hypokalemia-Induced Rhabdomyolysis as a result of Distal Renal Tubular Acidosis in a Pregnant Woman: A Case Report and Literature Review. (26788388)
2015
43
Distal renal tubular acidosis in primary hyperparathyroidism. (25634859)
2015
44
Hyperammonemia in Distal Renal Tubular Acidosis: A New Case and Review of the Literature. (26138379)
2015
45
Clinical and laboratory approaches in the diagnosis of renal tubular acidosis. (25823989)
2015
46
Renal tubular acidosis is highly prevalent in critically ill patients. (25888397)
2015
47
Whole-exome sequencing as a diagnostic tool for distal renal tubular acidosis. (26208211)
2015
48
A novel mutation pattern of kidney anion exchanger 1 gene in patients with distal renal tubular acidosis in Iran. (25957428)
2015
49
Decreased Renal Expression of H(+)-ATPase and Pendrin in a Patient with Distal Renal Tubular Acidosis Associated with SjAPgren's Syndrome. (26568006)
2015
50
Central diabetes insipidus, central hypothyroidism, renal tubular acidosis and dandy-walker syndrome: new associations. (25861538)
2015

Variations for Renal Tubular Acidosis

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Expression for genes affiliated with Renal Tubular Acidosis

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Search GEO for disease gene expression data for Renal Tubular Acidosis.

Pathways for genes affiliated with Renal Tubular Acidosis

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Pathways related to Renal Tubular Acidosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Erythrocytes take up carbon dioxide and release oxygen60
Show member pathways
9.8CA2, SLC4A1
2
Proximal tubule bicarbonate reclamation34
9.4CA2, SLC4A4, SLC9A3
3
Bile secretion34
9.4CA2, SLC4A4, SLC9A3
4
Phagosome34
9.4ATP6V0A4, ATP6V1B1, TCIRG1
5
Synaptic vesicle cycle34
Show member pathways
9.4ATP6V0A4, ATP6V1B1, TCIRG1
6
Rheumatoid arthritis34
9.4ATP6V0A4, ATP6V1B1, TCIRG1
7
Insulin receptor recycling60
Show member pathways
8.7ATP6V0A4, ATP6V1B1, CA2, SLC4A1, TCIRG1
8
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds60
Show member pathways
7.4ATP6V0A4, ATP6V1B1, SLC26A6, SLC4A1, SLC4A4, SLC4A7

GO Terms for genes affiliated with Renal Tubular Acidosis

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Cellular components related to Renal Tubular Acidosis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1apical part of cellGO:004517710.2ATP6V0A4, CA2, REN
2brush border membraneGO:003152610.0ATP6V0A4, SLC26A6, SLC9A3
3proton-transporting V-type ATPase, V0 domainGO:003317910.0ATP6V0A4, TCIRG1
4phagocytic vesicle membraneGO:00306709.8ATP6V0A4, OCRL, TCIRG1
5vacuolar proton-transporting V-type ATPase, V0 domainGO:00002209.6ATP6V0A4, TCIRG1
6vacuolar proton-transporting V-type ATPase complexGO:00164719.5ATP6V0A4, ATP6V1B1, TCIRG1
7basolateral plasma membraneGO:00163239.2ATP6V1B1, CA2, SLC26A6, SLC4A1, SLC4A4, SLC4A7
8apical plasma membraneGO:00163248.9ATP6V0A4, ATP6V1B1, SLC26A6, SLC4A7, SLC9A3, TCIRG1
9extracellular exosomeGO:00700628.7ATP6V0A4, ATP6V1B1, CA2, OCRL, SLC4A1, SLC4A4
10plasma membraneGO:00058866.7ATP6V0A4, CA2, OCRL, REN, SLC26A6, SLC4A1
11membraneGO:00160206.0ATP6V0A4, ATP6V1B1, CA2, NR3C2, OCRL, REN

Biological processes related to Renal Tubular Acidosis according to GeneCards Suite gene sharing:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1excretionGO:000758810.7ATP6V0A4, ATP6V1B1
2ATP synthesis coupled proton transportGO:001598610.4ATP6V0A4, TCIRG1
3positive regulation of dipeptide transmembrane transportGO:200115010.4CA2, SLC26A6
4inorganic anion transportGO:001569810.3SLC4A1, SLC4A4, SLC4A7
5regulation of pHGO:000688510.2ATP6V0A4, ATP6V1B1, SLC9A3
6ATP hydrolysis coupled proton transportGO:001599110.1ATP6V0A4, ATP6V1B1, TCIRG1
7insulin receptor signaling pathwayGO:000828610.1ATP6V0A4, ATP6V1B1, TCIRG1
8phagosome acidificationGO:009038310.1ATP6V0A4, ATP6V1B1, TCIRG1
9proton transportGO:001599210.1ATP6V0A4, ATP6V1B1, TCIRG1
10transferrin transportGO:003357210.1ATP6V0A4, ATP6V1B1, TCIRG1
11sodium ion transportGO:000681410.1SLC4A4, SLC4A7, SLC9A3
12vacuolar acidificationGO:00070359.9ATP6V0A4, TCIRG1
13anion transmembrane transportGO:00986569.8SLC26A6, SLC4A1, SLC4A4, SLC4A7
14anion transportGO:00068209.8SLC26A6, SLC4A1, SLC4A4, SLC4A7
15vacuolar proton-transporting V-type ATPase complex assemblyGO:00700729.6ATP6V0A4, TCIRG1
16bicarbonate transportGO:00157019.4CA2, SLC26A6, SLC4A1, SLC4A4, SLC4A7
17regulation of intracellular pHGO:00514538.9CA2, SLC26A6, SLC4A1, SLC4A4, SLC4A7, SLC9A3
18ion transportGO:00068118.2ATP6V0A4, ATP6V1B1, SLC26A6, SLC4A1, SLC4A4, SLC4A7
19transportGO:00068107.8ATP6V0A4, ATP6V1B1, SLC26A6, SLC4A1, SLC4A4, SLC4A7

Molecular functions related to Renal Tubular Acidosis according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1anion:anion antiporter activityGO:001530110.2SLC26A6, SLC4A1
2bicarbonate transmembrane transporter activityGO:001510610.2SLC26A6, SLC4A1
3chloride transmembrane transporter activityGO:001510810.2SLC26A6, SLC4A1
4sodium:bicarbonate symporter activityGO:00085109.8SLC4A4, SLC4A7
5hydrogen ion transmembrane transporter activityGO:00150789.8ATP6V0A4, ATP6V1B1, TCIRG1
6proton-transporting ATPase activity, rotational mechanismGO:00469619.7ATP6V0A4, TCIRG1
7anion transmembrane transporter activityGO:00085099.5SLC26A6, SLC4A1, SLC4A4, SLC4A7
8inorganic anion exchanger activityGO:00054529.4SLC26A6, SLC4A1, SLC4A4, SLC4A7

Sources for Renal Tubular Acidosis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z