MCID: RNL028
MIFTS: 55

Renal Tubular Dysgenesis malady

Categories: Genetic diseases, Rare diseases, Nephrological diseases, Fetal diseases

Aliases & Classifications for Renal Tubular Dysgenesis

About this section

Aliases & Descriptions for Renal Tubular Dysgenesis:

Name: Renal Tubular Dysgenesis 49 11 45 23 47 51 67
Primitive Renal Tubule Syndrome 45 23 51
Allanson Pantzar Mcleod Syndrome 23 65
 
Rtd 45 67
Renotubular Dysgenesis 51

Characteristics:

HPO:

61
renal tubular dysgenesis:
Inheritance: autosomal recessive inheritance


Classifications:



External Ids:

OMIM49 267430
Orphanet51 3033
ICD10 via Orphanet28 Q63.8
UMLS via Orphanet66 C0266313
UMLS65 C0266313

Summaries for Renal Tubular Dysgenesis

About this section
Genetics Home Reference:23 Renal tubular dysgenesis is a severe kidney disorder characterized by abnormal development of the kidneys before birth. In particular, kidney structures called proximal tubules are absent or underdeveloped. These structures help to reabsorb needed nutrients, water, and other materials into the blood and excrete everything else into the urine. Without functional proximal tubules, the kidneys cannot produce urine (a condition called anuria).

MalaCards based summary: Renal Tubular Dysgenesis, also known as primitive renal tubule syndrome, is related to renal tubular dysgenesis, ace-related and renal tubular dysgenesis, agt-related, and has symptoms including aplasia/hypoplasia of the lungs, premature birth and polyhydramnios. An important gene associated with Renal Tubular Dysgenesis is AGT (Angiotensinogen), and among its related pathways are Thromboxane signalling through TP receptor and Peptide hormone metabolism. Affiliated tissues include kidney, bone and lung, and related mouse phenotypes are adipose tissue and behavior/neurological.

UniProtKB/Swiss-Prot:67 Renal tubular dysgenesis: Autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).

OMIM:49 Autosomal recessive renal tubular dysgenesis is a severe disorder of renal tubular development characterized by... (267430) more...

Related Diseases for Renal Tubular Dysgenesis

About this section

Diseases in the Renal Tubular Dysgenesis family:

Renal Tubular Dysgenesis, Ace-Related Renal Tubular Dysgenesis, Agt-Related
Renal Tubular Dysgenesis, Agtr1-Related Renal Tubular Dysgenesis, Ren-Related
Renal Tubular Dysgenesis Due to Twin-Twin Transfusion

Diseases related to Renal Tubular Dysgenesis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 87)
idRelated DiseaseScoreTop Affiliating Genes
1renal tubular dysgenesis, ace-related12.1
2renal tubular dysgenesis, agt-related12.1
3renal tubular dysgenesis, agtr1-related12.1
4renal tubular dysgenesis, ren-related12.1
5renal tubular dysgenesis due to twin-twin transfusion12.1
6drug-related renal tubular dysgenesis12.1
7renal tubular dysgenesis of genetic origin12.1
8pediatric multiple sclerosis10.2ACE, AGT
9parametritis10.2ACE, AGT
10hemochromatosis10.2
11oligohydramnios10.2
12ceroid lipofuscinosis, neuronal, 610.2ACE, AGT
13subclavian steal syndrome10.2ACE, AGT
14hyposmia nasal hypoplasia hypogonadism10.2ACE, REN
15kidney cortex necrosis10.1ACE, REN
16atrial septal defect 7, with or without av conduction defects10.1ACE, REN
17hypochromic microcytic anemia with iron overload10.1ACE, REN
18malignant hypertension10.1ACE, REN
19hypoaldosteronism, congenital, due to cmo ii deficiency10.1AGT, REN
20multicentric reticulohistiocytosis10.1ACE, REN
21neonatal hemochromatosis10.1
22purpura simplex10.1ACE, REN
23anisomastia10.1AGT, REN
24periampullary adenoma10.0ACE, REN
25obstructive sleep apnea10.0ACE, REN
26heart disease10.0ACE, REN
27organic acidemia10.0ACE, REN
28carbohydrate metabolic disorder10.0ACE, REN
29ischemic optic neuropathy9.9ACE, AGTR1
30meningococcemia9.9AGT, AGTR1
31patau syndrome9.9ACE, AGTR1
32inguinal hernia9.9ACE, REN
33acute myeloblastic leukemia with maturation9.9ACE, AGTR1
34fetal erythroblastosis9.9ACE, AGTR1
35bernard-soulier syndrome, type a29.9ACE, AGTR1
363mc syndrome9.9ACE, AGT
37orofaciodigital syndrome9.9ACE, REN
38microcephaly9.9
39nephrocalcinosis9.9
40nephronophthisis9.9
41intestinal perforation9.9
42ischemia9.9
43kidney disease9.9
44antiphospholipid syndrome9.9ACE, AGTR1
45preeclampsia/eclampsia 19.9AGT, AGTR1
46mitochondrial metabolism disease9.8ACE, REN
47codas syndrome9.8ACE, AGT
48chronic venous insufficiency9.8ACE, AGTR1
49familial hyperthyroidism due to mutations in tsh receptor9.8AGTR1, REN
50sympathetic ophthalmia9.8AGTR1, REN

Graphical network of the top 20 diseases related to Renal Tubular Dysgenesis:



Diseases related to renal tubular dysgenesis

Symptoms for Renal Tubular Dysgenesis

About this section

Symptoms by clinical synopsis from OMIM:

267430

Clinical features from OMIM:

267430

Symptoms:

 51 (show all 14)
  • hypertelorism
  • hypoplastic lungs/pulmonary hypoplasia/agenesis
  • polycystic kidneys
  • renal tubular defect/tubulopathy
  • hyperextensible joints/articular hyperlaxity
  • autosomal recessive inheritance
  • stillbirth/neonatal death
  • polyhydramnios
  • prematurity
  • microcephaly
  • simian crease/transverse/unique palmar crease
  • tetralogy of fallot/trilogy of fallot
  • renal disease/nephropathy
  • oligoamnios

HPO human phenotypes related to Renal Tubular Dysgenesis:

(show all 21)
id Description Frequency HPO Source Accession
1 aplasia/hypoplasia of the lungs hallmark (90%) HP:0006703
2 premature birth hallmark (90%) HP:0001622
3 polyhydramnios hallmark (90%) HP:0001561
4 joint hypermobility hallmark (90%) HP:0001382
5 hypertelorism hallmark (90%) HP:0000316
6 polycystic kidney dysplasia hallmark (90%) HP:0000113
7 abnormality of the renal tubule hallmark (90%) HP:0000091
8 tetralogy of fallot occasional (7.5%) HP:0001636
9 oligohydramnios occasional (7.5%) HP:0001562
10 single transverse palmar crease occasional (7.5%) HP:0000954
11 microcephaly occasional (7.5%) HP:0000252
12 nephropathy occasional (7.5%) HP:0000112
13 anuria HP:0100519
14 renotubular dysgenesis HP:0008660
15 widely patent fontanelles and sutures HP:0004492
16 hypotension HP:0002615
17 respiratory insufficiency HP:0002093
18 pulmonary hypoplasia HP:0002089
19 potter facies HP:0002009
20 oligohydramnios HP:0001562
21 microcephaly HP:0000252

Drugs & Therapeutics for Renal Tubular Dysgenesis

About this section

Drugs for Renal Tubular Dysgenesis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 105)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Efavirenzapproved, investigationalPhase 4398154598-52-464139
Synonyms:
(-)-6-CHLORO-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one
(-)-Efavirenz
(4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(4S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
(4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one
(S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-ben
(S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one
(S)-6-chloro-4-(Cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
(S)-6-chloro-4-Cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[D][1,3]oxazin-2-one
154598-52-4
1ikv
1ikw
2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)- (9
6-chloro-4-(2-Cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[D][1,3]oxazin-2-one
6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one
AC-19049
AC1L20IX
BIDD:GT0383
C08088
C14H9ClF3NO2
CHEBI:119486
CHEMBL223228
CID64139
CPD000466351
D00896
DB00625
DB07709
DMP 266
DMP-266
EFV
 
EFZ
Efavirenz
Efavirenz (JAN/INN)
Efavirenzum
Eravirenz
HMS2051J08
HMS2090N16
HSDB 7163
L 743726
L-741211
L-743,726
L-743725
L-743726
LS-173464
MLS000759465
MLS001424087
Met-SDF-1.beta. & Efavirenz
Met-Stromal Cell-derived Factor-1.beta. (Human) & Efavirenz
MolPort-003-983-924
NSC742403
SAM001246667
SBB066062
SMR000466351
Stocrin
Strocin (TM)
Sustiva
Sustiva (TM)
Sustiva (TN)
UNII-JE6H2O27P8
ZINC02020233
efavirenz
efavirenz, (S)-isomer
zoxazin-2-one
Éfavirenz
2
Emtricitabineapproved, investigationalPhase 4394143491-57-060877
Synonyms:
(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-.beta.-L-FTC
(-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
(-)-2'-Deoxy-5-fluoro-3'-thiacytidine
(-)-FTC
(-)-beta-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
(-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine
(-)-cis-4-amino-5-Fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
(-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
(2R-cis)-4-Amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
(2R-cis)-4-amino-5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
.beta.-L-(-)-(2R,5S)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
1-(2-(Hydroxymethyl)oxathiolan-5-yl)-5-fluorocytosine
143491-54-7
143491-57-0
145213-48-5
2',3',5-FTC
2',3'-Dideoxy-5-fluoro-3'-thiacytidine
2'-Deoxy-5-fluoro-3'-oxa-4'-thiocytidine
2'-Deoxy-5-fluoro-3'-thiacytidine
2-FTC
3'-Thia-2'.3'-dideoxy-5-fluorocytidine
4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one
4-Amino-5-fluoro-1-[(2R,5S)-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
4-amino-5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
5-Fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)[1,3]oxathiolan-5-yl]cytosine
524W91
AC1L1U3I
AC1Q4KUB
BW 1592
 
BW 524W91
BW-524W91
BW524W91
C122114
C12599
C8H10FN3O3S
CHEBI:31536
CHEMBL885
CID60877
Coviracil
Coviracil(TM)
D01199
DB00879
DRG-0208
Emtricitabin
Emtricitabina
Emtricitabine
Emtricitabine (JAN/USAN/INN)
Emtricitabinum
Emtriva
Emtriva (TN)
Emtriva(TM)
FT-0080009
HMS2089I05
HSDB 7337
LS-135838
LS-173184
NCGC00164564-01
RCV
Racivir
SBB066061
TL8000958
UNII-G70B4ETF4S
ZINC03629271
beta-L-2',3'-dideoxy-5-fluoro-3'-thiacytidine
dOTFC
emtricitabine
3
Lamivudineapproved, investigationalPhase 4594134678-17-460825
Synonyms:
(+/-) (Cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(+/-)-3TC
(+/-)-BCH-189
(+/-)-SddC
(-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine
(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
(-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-2'-Deoxy-3'-thiacytidine
(-)-BCH 189
(-)-BCH-189
(-)-SddC
(-)-beta-L-2',3'-Dideoxy-3'-thiacytidine
(-)NGPB-21
(2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
.beta.-L-(-)-2',3'-dideoxy-3'-thiacytidine & Sho-Saiko-To
134678-17-4
2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (+/-) (Cis)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Galanthus Nivalis Agglutinin (GNA)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Hippeastrum hybrid agglutinin( HHA)
3'-Thia-2',3'-dideoxycytidine
3-TC
3TC
3TC & GNA
3TC & SST
3TC (AIDS INITIATIVE) (AIDS INITIATIVE)
3TC and NV-01
3TC, Zeffix, Heptovir, Epivir, Epivir-HBV, Lamivudine
4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
480434-79-5
AC-1416
AC1L1TZZ
AC1Q6C34
BCH 189
BCH-189
BCH-790
BCH189
BIDD:GT0033
Bio-0652
C07065
C8H11N3O3S
CCRIS 9274
CHEBI:133986
CHEMBL141
CID60825
CPD000466319
D00353
D019259
DB00709
 
DRG-0126
DTHC
Epivir
Epivir (TN)
Epivir HBV
Epivir(TM)
Epivir-HBV
Epzicom
FT-0082667
GG-714
GR 109714 X
GR 109714X
GR-109714X
GR109714X
HHA & 3TC
HHA & Lamivudine
HMS2051D21
HSDB 7155
Hepitec
Heptivir
Heptodin
Heptovir
L0217
LMV
LS-2107
Lamivir
Lamivudin
Lamivudina
Lamivudine
Lamivudine & GNA
Lamivudine (JAN/USP/INN)
Lamivudine [USAN:BAN:INN]
Lamivudine [USAN:INN:BAN]
Lamivudine [Usan:Ban:Inn]
Lamivudine, (2S-cis)-Isomer
Lamivudinum
MLS000759424
MLS001424097
MolPort-002-507-347
NCGC00159341-03
NCGC00159341-04
NSC620753
S1706_Selleck
SAM001246582
SAM002589994
SMR000466319
STK801940
UNII-2T8Q726O95
ZINC00012346
Zeffix
Zefix
beta-L-2',3'-Dideoxy-3'-thiacytidine
beta-L-3'-Thia-2',3'-dideoxycytidine
lamivudine
4
Tenofovirapproved, investigationalPhase 4666147127-20-6464205
Synonyms:
(R)-9-(2-Phosphonomethoxypropyl)adenine
(R)-9-(2-Phosphonylmethoxypropyl)adenine
(R)-PMPA
147127-20-6
206184-49-8
AC-760
AC1LA9BO
Anh. tenofovir
Anhydrous tenofovir
Apropovir
CHEBI:45809
CHEMBL483
CID464205
D,L-Tenofovir
DB00300
GNA & Tenofovir
GS 1275
GS 1278
GS1278
HHA & Tenofovir
 
KS-5021
MolPort-003-850-411
NCGC00167535-01
PMPA
PMPA-(R)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Galanthus nivalis agglutinin (GNA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Hippeastrum hybrid agglutinin( HHA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- (9CI)
Phosphonic acid, [[2-(6-amino-9H-purin-9
S1401_Selleck
TDF
TFV
Tenefovir
Tenofovir
Tenofovir (anh.)
Tenofovir Disoproxil Fumarate
Tenofovir disoproxil
Tenofovir disoproxil fumarate
UNII-99YXE507IL
Viread
Viread, Tenofovir
[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
5
Abacavirapproved, investigationalPhase 4203136470-78-565140, 441300
Synonyms:
(+/-)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol
(+/-)-Abacavir
(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol
136470-78-5
1592U89
168146-84-7
ABC
AC1L9AXG
Abacavir
Abacavir (INN)
Abacavir Sulfate
Abacavir [INN]
Bio-0001
C07624
 
CHEBI:421707
CHEMBL1380
CID441300
D07057
DB01048
Epzicom
NCGC00164560-01
NCGC00164560-02
NSC742406
Trizivir
ZINC02015928
Ziagen
Ziagen (TM)(*Succinate salt*)
[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol
abacavir
{(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol
6
Ritonavirapproved, investigationalPhase 4850155213-67-5392622
Synonyms:
1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
155213-67-5
1hxw
1sh9
5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S)-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate
5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate
538, ABT
A-84538
ABBOTT-84538
ABT 538
ABT 84538
ABT-538
ABT538
AC-733
AC1L94GB
AKOS000280930
Abbott 84538
BIDD:GT0387
BIDD:PXR0023
Bio-0093
C07240
C37H48N6O5S2
CHEBI:45409
CHEMBL163
CID392622
CPD000466395
D00427
D019438
 
DB00503
DRG-0244
FT-0082824
HMS2051B08
HSDB 7160
LS-148860
MLS000759541
MLS001424063
MolPort-000-883-877
N-[(2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl]-N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-L-valinamide
NCGC00159462-02
NSC693184
Norvir
Norvir (TM)
Norvir (TN)
Norvir Sec
RIT
RTV
Ritonavir
Ritonavir (JAN/USAN/INN)
Ritonavir [USAN]
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and AIDS.
Ritonavirum
S1185_Selleck
SAM001246783
SMR000466395
STK634209
ZINC03944422
ritonavir
7
GliclazideapprovedPhase 45521187-98-43475
Synonyms:
1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea
1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea
1-(3-Azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulphonylurea
1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea
21187-98-4
AB00053165
AB1004595
AC-12045
AC1L1G0Q
AKOS003237903
BPBio1_000699
BRD-A61154809-001-04-3
BRN 1657836
BSPBio_000635
BSPBio_003304
Bio-0502
C15H21N3O3S
CHEBI:31654
CHEMBL427216
CID3475
D01599
DB01120
Diaikron
Diamicron
Diamicron MR
DivK1c_006966
EINECS 244-260-5
G2167_SIGMA
Gliclazida
Gliclazida [INN-Spanish]
Gliclazide
Gliclazide (JAN/INN)
Gliclazide [BAN:INN:DCF:JAN]
Gliclazidum
Gliclazidum [INN-Latin]
Gliklazid
Glimicron
Glimicron (TN)
Glyclazide
HMS1569P17
HMS1922D15
HMS2090K16
I06-0117
 
KBio1_001910
KBio2_001958
KBio2_004526
KBio2_007094
KBio3_002806
KBioGR_001096
KBioSS_001958
LS-160299
MLS001215197
MLS001304077
MLS001304118
MolPort-002-507-779
Mylan-Gliclazide
N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea
N-(hexahydrocyclopenta[c]pyrrol-2(1H)-ylcarbamoyl)-4-methylbenzenesulfonamide
N-[(hexahydrocyclopenta[c]pyrrol-2(1H)-ylamino)carbonyl]-4-methylbenzenesulfonamide
NCGC00095107-01
NCGC00095107-02
NCGC00095107-03
NCGC00095107-04
NCGC00095107-05
NCGC00095107-06
Nordialex
PMS-Gliclazide
Prestwick0_000558
Prestwick1_000558
Prestwick2_000558
Prestwick3_000558
Prestwick_869
S 1702
S 852
S-1702
S-852
SE 1702
SMR000542971
SPBio_002556
SPECTRUM1504145
SPECTRUM1505013
STK803142
SpecPlus_000870
Spectrum3_001862
Spectrum4_000598
Spectrum5_000753
Spectrum_001478
gliclazide
8
MetforminapprovedPhase 41645657-24-9, 1115-70-414219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMBG
DMGG
Diabefagos
Diabetosan
Diabex
Diaformin
Dianben
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Meguan
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin Hydrochloride
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
Obimet
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
9
Miconazoleapproved, investigationalPhase 4, Phase 1302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
10
SpironolactoneapprovedPhase 41591952-01-7, 52-01-75833
Synonyms:
4-18-00-01601 (Beilstein Handbook Reference)
4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate
496916-40-6
52-01-7
7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
AB00513806
AC-4214
AC1L1L8Q
Abbolactone
Acelat
Aldace
Aldactazide
Aldactide
Aldactone
Aldactone (TN)
Aldactone A
Alderon
Aldopur
Almatol
Alphapharm Brand of Spironolactone
Alpharma Brand of Spironolactone
Alter Brand of Spironolactone
Altex
Aquareduct
Ashbourne Brand of Spironolactone
Azupharma Brand of Spironolactone
BIDD:PXR0071
BPBio1_000194
BRD-K90027355-001-03-4
BRN 0057767
BSPBio_000176
C07310
C24H32O4S
CHEBI:428201
CHEBI:45692
CHEBI:9241
CHEMBL1393
CID5833
CPD000471892
Cardel Brand of Spironolactone
D00443
D013148
DB00421
Deverol
Dexo Brand of Spironolactone
Diatensec
Dira
Duraspiron
EINECS 200-133-6
Espironolactona
Espironolactona Alter
Espironolactona Mundogen
Espironolactona [INN-Spanish]
Euteberol
Flumach
Frumikal
Generosan Brand of Spironolactone
HMS1568I18
HMS2090N21
HSDB 3184
Hormosan Brand of Spironolactone
I06-1970
Jenapharm Brand of Spironolactone
Jenaspiron
LS-118614
LT00772287
Lacalmin
Lacdene
Laractone
MLS001074672
MLS001333253
MLS001333254
MLS002153245
MLS002207058
Mayoly-Spindler Brand of Spironolactone
Melarcon
Merck dura Brand of Spironolactone
Mundogen Brand of Spironolactone
NCGC00164397-01
 
NCGC00164397-02
NSC 150399
NSC150399
Nefurofan
Novo Spiroton
Novo-Spiroton
NovoSpiroton
Novopharm Brand of Spironolactone
Osyrol
Pfizer Brand of Spironolactone
Pharmafrid Brand of Spironolactone
Practon
Prestwick0_000128
Prestwick1_000128
Prestwick2_000128
Prestwick3_000128
Roche Brand of Spironolactone
S0260
S3378_SIGMA
SAM002264648
SC 9420
SC-9420
SC9420
SMR000471892
SNL
SPBio_002115
Sagisal
Searle Brand of Spironolactone
Sincomen
Spiractin
Spiresis
Spiretic
Spiridon
Spiro L.U.T.
Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan)
Spiro-Tablinen
Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]
Spirobeta
Spiroctan
Spiroctanie
Spiroderm
Spirogamma
Spirolactone
Spirolakton
Spirolang
Spirolone
Spirone
Spirono Isis
Spirono-Isis
Spironocompren
Spironolactone
Spironolactone (JP15/USP/INN)
Spironolactone A
Spironolactone [BAN:INN:JAN]
Spironolactone [INN:BAN:JAN]
Spironolactonum
Spironolactonum [INN-Latin]
Spironolattone
Spironolattone [DCIT]
Spironone
Spirospare
Sprioderm
Supra-puren
Suracton
UNII-27O7W4T232
Uractone
Urusonin
Veroshpiron
Verospiron
Verospirone
Verospirone Opianin
WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ
Worwag Brand of Spironolactone
Xenalon
ZINC03861599
betapharm Brand of Spironolactone
ct Arzneimittel Brand of Spironolactone
ct-Arzneimittel Brand of Spironolactone
spiro von ct
spironolactone
spironolattone
von ct, spiro
11
Amphotericin Bapproved, investigationalPhase 41171397-89-314956, 5280965
Synonyms:
12633-72-6
1397-89-3
30782-62-8
5-18-10-00525 (Beilstein Handbook Reference)
54482-28-9
8055-20-7
AB00513832
ABLC
AC1L1CN2
AC1L24V6
AC1L70KF
AC1L73U6
AC1NQXTD
AC1NTQ32
AC1NUQG4
AC1NY9JC
AC1O7GCZ
AC1O8FQV
AC1O8PFK
AI3-26528
AMPH-B
AMPH-b
Abelcet
Abelecet
AmBisome (TN)
Ambap1397-89-3
Ambisome
Amfotericina B
Amfotericina B [INN-Spanish]
Ampho-Moronal
Amphocin
Amphomoronal
Amphortericin B
Amphotec
Amphotec (TN)
Amphotericin
Amphotericin .BETA.
Amphotericin B
Amphotericin B (JP15/USP/INN)
Amphotericin B Cholesterol Dispersion
Amphotericin B Cholesteryl Sulfate Complex
Amphotericin B Colloidal Dispersion
Amphotericin B [USAN:INN:JAN]
Amphotericin B, Lipid-based
Amphotericin B, Streptomyces sp.
Amphotericin-B
Amphotericine B
Amphotericine B [INN-French]
Amphotericinum
Amphotericinum B
Amphotericinum B [INN-Latin]
Amphotherizin
Amphotherizin [German]
Amphotéricine B
Amphozone
BIDD:GT0351
BPBio1_000374
BRN 0078342
BSPBio_000340
C-AmB
C06573
C47H73NO17
CCRIS 5963
CHEBI:2682
CHEMBL1200646
CHEMBL267345
CID10533925
CID10629638
CID10677275
CID14956
 
CID1972
CID352546
CID354192
CID5280965
CID5386092
CID5458486
CID5771695
CID6604295
CID6708817
CID6713692
CID9919339
D00203
DB00681
DivK1c_007045
EINECS 215-742-2
Fungilin
Fungisome
Fungisone
Fungizone
Fungizone (TN)
HMS1569A22
HSDB 3008
HSDB 3008 IAB
Halizon
I06-0257
KBio1_001989
KBio2_000551
KBio2_003119
KBio2_005687
KBioGR_002298
KBioSS_000551
LMPK06000002
LNS-AmB
LS-187721
LS-93
Liposomal Amphotericin B
Liposomal amphotericin b
MLS002702966
MolPort-006-392-260
Mysteclin-F
NCGC00014913
NCGC00090808-01
NCGC00098014-01
NCGC00179595-01
NCI527017
NCI60_004288
NCIStruc1_001042
NCIStruc2_000920
NKTR-024
NS 718
NSC 527017
NSC-527017
NSC527017
Prestwick0_000410
Prestwick1_000410
Prestwick2_000410
Prestwick3_000410
Prestwick_721
SMP1_000302
SMR001566780
SPBio_000715
SPBio_002279
ST50999656
SinuNase
SpecPlus_000949
Spectrum2_000818
Spectrum4_001779
Spectrum_000111
UNII-7XU7A7DROE
amophotericin B
amphotericin B liposomal
amphotericin b
12Anti-Bacterial AgentsPhase 4, Phase 19140
13MineralocorticoidsPhase 4301
14Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 1, Phase 29988
15Hormone AntagonistsPhase 4, Phase 1, Phase 210002
16Reverse Transcriptase InhibitorsPhase 41656
17HormonesPhase 4, Phase 1, Phase 211748
18Protease InhibitorsPhase 44558
19Atazanavir SulfatePhase 4222
20Anti-Retroviral AgentsPhase 42794
21CobicistatPhase 470
22Cytochrome P-450 CYP3A InhibitorsPhase 41421
23Antiviral AgentsPhase 4, Phase 18071
24Cytochrome P-450 Enzyme InhibitorsPhase 43036
25Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationPhase 465
26Nucleic Acid Synthesis InhibitorsPhase 43836
27HIV Protease InhibitorsPhase 44558
28Anti-Infective AgentsPhase 4, Phase 2, Phase 117220
29Emtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationPhase 4130
30Pharmaceutical SolutionsPhase 47004
31Hypoglycemic AgentsPhase 44503
32Antifungal AgentsPhase 4, Phase 13015
33Mineralocorticoid Receptor AntagonistsPhase 4284
34Natriuretic AgentsPhase 41403
35diureticsPhase 41194
36Antiprotozoal AgentsPhase 41730
37Liposomal amphotericin BPhase 4117
38Diuretics, Potassium SparingPhase 41445
39Antiparasitic AgentsPhase 41854
40
SulfamethoxazoleapprovedPhase 2139723-46-65329
Synonyms:
129378-89-8
3-(Para-Aminophenylsulphonamido)-5-methylisoxazole
3-(p-Aminobenzenesulfonamido)-5-methylisoxazole
3-(p-Aminophenylsulfonamido)-5-methylisoxazole
3-(para-Aminophenylsulphonamido)-5-methylisoxazole
3-Sulfanilamido-5-methylisoxazole
3-Sulphanilamido-5-methylisoxazole
4-Amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
4-Amino-N-(5-methyl-3-isoxazolyl)-Benzenesulfonamide
4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide
4-Amino-N-(5-methyl-isoxazol-3-yl)-benzenesulfonamide
4-Amino-N-[5-methyl-3- isoxazolyl]benzenesulfonamide
4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
4-amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide
46850_RIEDEL
5-Methyl-3-sulfanilamidoisoxazole
5-Methyl-3-sulfanylamidoisoxazole
5-Methyl-3-sulfonylamidoisoxazole
5-Methyl-3-sulphanil-amidoisoxazole
723-46-6
A047
AB00052099
AC-11118
AC1L1K42
AC1Q2J5R
AKOS000200952
ALBB-002089
ARONIS018156
Apo-Sulfamethoxazole
Azo Gantanol
Azo-Gantanol
Azo-gantanol
BAS 00836086
BB_SC-1251
BIDD:GT0731
BPBio1_000081
BRD-K28494619-001-05-0
BRN 0226453
BSPBio_000073
BSPBio_002028
Bactrim
Bactrimel
C07315
C10H11N3O3S
CAS-723-46-6
CCRIS 567
CHEBI:9332
CHEMBL443
CID5329
CPD000058223
D00447
D013420
DB01015
DivK1c_000649
EINECS 211-963-3
Gamazole
Gantanol
Gantanol (TN)
Gantanol (tn)
Gantanol-DS
HMS1568D15
HMS1921A21
HMS2092K03
HMS502A11
HMS561O18
HSDB 3186
I01-0154
IDI1_000649
InChI=1/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
KBio1_000649
KBio2_001474
KBio2_004042
KBio2_006610
KBio3_001528
KBioGR_000749
KBioSS_001474
LS-1620
MLS000069732
MLS001055354
MLS001074165
MS 53
Maybridge1_007190
Metoxal
MolPort-000-145-787
N'-(5-Methyl-3-isoxazole)sulfanilamide
 
N'-(5-Methyl-3-isoxazolyl)-Sulfanilamide
N'-(5-Methyl-3-isoxazolyl)sulfanilamide
N'-(5-Methylisoxazol-3-yl)sulphanilamide
N(Sup1)-(5-Methyl-3-isoxazolyl)sulfanilamide
N(sup 1)-(5-Methyl-3-isoxazolyl)sulfanilamide
N(sup 1)-(5-Methyl-3-isoxazolyl)sulphanilamide
N(sup1)-(5-Methyl-3-isoxazolyl)sulfanilamide
N1-(5-Methyl-3-isoxazolyl)sulfanilamide
N1-(5-Methyl-3-isoxazolyl)sulphanilamide
N1-(5-Methylisoxazol-3-yl)sulfanilamide
N1-(5-methyl-3-isoxazolyl)-Sulfanilamide
NCGC00016533-01
NCGC00016533-02
NCGC00021995-03
NCGC00021995-04
NCGC00021995-05
NINDS_000649
NSC 147832
NSC147832
N^1-(5-Methyl-3-isoxazolyl)-Sulfanilamide
Ndimethyl1-(5-methyl-3-isoxazolyl)-Sulfanilamide
Oprea1_114486
Oprea1_285680
Prestwick0_000177
Prestwick1_000177
Prestwick2_000177
Prestwick3_000177
Prestwick_453
Radonil
Ro 4-2130
Ro 6-2580/11
Ro-4-2130
S0361
S1915_Selleck
S7507_FLUKA
S7507_SIGMA
SAM002554930
SIM
SMR000058223
SMX
SPBio_000896
SPBio_001994
SPECTRUM1500550
STK007988
SULFAMETHOXAZOLE (8064-90-2 (TRIMETHOPRIM/SULFAMETHOXAZOLE)
Septran
Simsinomin
Sinomin
Solfametossazolo
Solfametossazolo [DCIT]
Spectrum2_000788
Spectrum3_000584
Spectrum4_000345
Spectrum5_000982
Spectrum_000994
Sulfamethalazole
Sulfamethoxazol
Sulfamethoxazole
Sulfamethoxazole (JP15/USP/INN)
Sulfamethoxazole [USAN:INN:JAN]
Sulfamethoxazole sodium
Sulfamethoxazole(USAN)
Sulfamethoxazolum
Sulfamethoxazolum [INN-Latin]
Sulfamethoxizole
Sulfamethylisoxazole
Sulfametoxazol
Sulfametoxazol [INN-Spanish]
Sulfanilamide, N1-(5-methyl-3-isoxazolyl)- (8CI)
Sulfisomezole
Sulpha-Methoxizole
Sulpha-methoxizole
Sulphamethalazole
Sulphamethoxazol
Sulphamethoxazole
Sulphamethoxazole BP 98
Sulphamethylisoxazole
Sulphisomezole
TL8005058
TMP/SMX (MIXTURE))
Trib
UNII-JE42381TNV
Urobak
WLN: T5NOJ C1 EMSWR DZ
ZINC00089763
nchembio.221-comp24
sulfamethoxazole
41
DanazolapprovedPhase 1, Phase 21517230-88-528417
Synonyms:
(17a)-Pregna-2,4-dien-20-yno[2,3-D]isoxazol-17-ol
(1R,3aS,3bR,10aR,10bS,12aS)-1-ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
(1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4(8),5,9-trien-17-ol
1-Ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
1-Ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-Cyclopenta[7,8]phenanthro[3,2-D]isoxazol-1-ol
17 alpha-Pregna-2,4-dien-20-yno[2,3-D] isoxazol-17 beta-ol
17-alpha-2,4-Pregnadien-20-yno(2,3-d)isoxazol-17-ol
17-alpha-Pregn-4-en-20-yno(2,3-d)isoxazol-17-ol
17-alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol
17.Alpha.-Pregna-2, {4-dien-20-yno[2,3-d]isoxazol-17-ol}
17230-88-5
17a-Pregna-2,4-dien-20-yne-[2,3-D]isoxazole-17b-ol
17a-Pregna-2,4-dien-20-yno[2,3-D]isoxazol-17-ol
17alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol
1H-Cyclopenta[7,8]phenanthro[3,2-D]isoxazole- pregna-2,4-dien-20-yno[2,3-D]isoxazol-17-ol deriv.
AC-6836
AC1L1FAD
AC1Q282K
AC1Q29FD
Alphapharm Brand of Danazol
Antigen Brand of Danazol
BPBio1_000100
BRD-K48970916-001-03-0
BSPBio_000090
Bonzol
CCRIS 6747
CHEBI:4315
CHEMBL1479
CID28417
CPD000058321
Chronogyn
Cyclomen
D00289
D003613
DB01406
Danatrol
Danazant
Danazol
Danazol (JAN/USP/INN)
Danazol [USAN:BAN:INN:JAN]
Danazol-ratiopharm
Danazole
Danazolum
Danazolum [INN-Latin]
 
Danocrine
Danocrine (TN)
Danogen
Danokrin
Danol
Danoval
Danovaol
Danzol
EINECS 241-270-1
HMS1568E12
HMS2090A22
Kendrick Brand of Danazol
LS-118524
Ladogal
MLS001066617
MLS001306473
MolPort-002-513-504
NCGC00164400-01
NCGC00179665-01
NSC 270916
NSC270916
Norciden
Panacrine
Prestwick0_000105
Prestwick1_000105
Prestwick2_000105
Prestwick3_000105
Prestwick_150
SAM002564203
SMR000058321
SPBio_002029
STOCK1N-23495
Sanofi Brand of Danazol
Sanofi Synthelabo Brand of Danazol
Sanofi Winthrop Brand of Danazol
UNII-N29QWW3BUO
WIN 17,757
WIN 17757
WIN-17757
Win 17, 757
Winobanin
ZINC03881958
[1,2]oxazolo[4',5':2,3]-17alpha-pregn-4-en-20-yn-17-ol
anatrol
danazol
ratiopharm Brand of Danazol
42Immunologic FactorsPhase 2, Phase 118483
43Adjuvants, ImmunologicPhase 21783
44lenograstimPhase 21134
45EstrogensPhase 1, Phase 22144
46Estrogen AntagonistsPhase 1, Phase 21155
47
Mycophenolic acidapprovedPhase 189824280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
Melbex
 
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolic Acid
Mycophenolsaeure
Myfortic
48
Mycophenolate mofetilapproved, investigationalPhase 1898128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate Mofetil
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
49
AbataceptapprovedPhase 1139332348-12-610237
Synonyms:
CTLA4-Ig
CTLA4-IgG4m
 
CTLA4Ig
CTLA4IgG4m
Orencia
50
VidarabineapprovedPhase 123824356-66-932326, 21704
Synonyms:
(+)-Cyclaradine
.beta.-Adenosine
.beta.-D-Adenosine
1odi
2-(6-AMINO-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
2946-52-3
2fqy
2gl0
30143-02-3
3080-29-3
3228-71-5
4005-33-8
46946-45-6
46969-16-8
524-69-6
5536-17-4
58-61-7
9-Arabinosyladenine
9-beta-D-Arabinofuranosyl-9H-purin-6-amine
9-beta-D-Arabinofuranosyl-adenine
9-beta-D-Arabinofuranosyladenine
9-beta-D-arabinofuranosyl-adenine
9-β-D-arabinofuranosyl-9H-purin-6-amine
9-β-D-arabinofuranosyladenine
A 9251
A0152
A4036_SIGMA
A4676_SIGMA
A5762_SIGMA
A9251_SIGMA
AC1L18OL
AC1L1U8O
AC1L2IWM
AC1L2SCM
AC1O4WIN
AC1O8PY7
AC1Q1ID3
AC1Q4Y1Z
AC1Q52XU
ADENOSINE, U.S.P.
ADN
AI3-52413
AI3-52821
AR-1H6029
ARA-A NSC 247519
Ade-Rib
Adenine Arabinoside
Adenine arabinoside
Adenine nucleoside
Adenine riboside
Adenine xyloside
Adenocard
Adenocard (TN)
Adenocard, Adenosine
Adenocor
Adenoscan
Adenoscan (TN)
Adenosin
Adenosin [German]
Adenosine (JAN/USP)
Adenosine [USAN:BAN]
Adenosine arabinose
Adenosine-8-14C
Adensoine
Ambap5536-17-4
Ara A
Ara-A
Ara-ATP
Araadenosine
Arabinoside Adenine
Arabinoside adenine
Arabinosyl Adenine
Arabinosyl adenine
Arabinosyl-adenine
Arabinosyladenine
Arasena-A
Armes
Armes (TN)
BB_NC-0565
BPBio1_000898
BRN 0624881
BSPBio_000816
BSPBio_001796
BSPBio_002000
Bio1_000437
Bio1_000926
Bio1_001415
Boniton
C00212
CAS-5536-17-4
CCRIS 2557
CCRIS 3383
CHEBI:136932
CHEBI:16335
CHEBI:45327
CHEMBL1090
CHEMBL20247
CHEMBL477
CI 673
CI-673
CID102198
CID191
CID21704
CID60961
CID6420052
CID6713976
CPD000471872
Caswell No. 010B
D000241
D00045
D06298
DB00640
DivK1c_000191
EINECS 200-389-9
EINECS 217-911-6
EINECS 226-893-9
EU-0100123
FT-0082881
HMS1570I18
HMS1920A13
HMS1921K05
HMS2090F06
HMS2091G13
HMS2092C16
HMS500J13
HSDB 6514
 
I01-1121
IDI1_000191
KBio1_000191
KBio2_002418
KBio2_004986
KBio2_007554
KBio3_001296
KBio3_001500
KBioGR_001224
KBioSS_002424
L000094
LS-15059
LS-15085
Lopac0_000123
MEDR-640
MLS000069638
MLS000699527
MLS001066352
MLS001333133
MLS001333134
MLS002153227
MLS002153992
MolPort-001-785-903
MolPort-001-838-229
MolPort-003-666-308
Myocol
NCGC00016656-01
NCGC00023673-03
NCGC00023673-04
NCGC00023673-05
NCGC00023673-06
NCGC00023673-07
NCGC00094579-01
NCGC00094579-02
NCGC00094579-03
NCGC00094579-04
NCGC00178869-01
NCGC00179417-01
NCI60_003823
NCI60_037192
NCIOpen2_003303
NCIOpen2_005376
NINDS_000191
NSC 247519
NSC 404241
NSC 627048
NSC 7359
NSC 7652
NSC-404241
NSC247519
NSC404241
NSC627048
NSC70422
NSC7359
NSC7652
NSC80832
NSC87676
NSC91041
Nucleocardyl
PDSP1_001036
PDSP2_001020
Pallacor
Polyadenosine
Polyriboadenosine
Prestwick0_000768
Prestwick1_000768
Prestwick2_000768
Prestwick3_000768
Prestwick_983
RAB
S1647_Selleck
S1784_Selleck
SAM002564191
SMP1_000312
SMR000058216
SMR000225041
SMR000471872
SMR001233326
SPBio_001194
SPBio_001491
SPBio_002755
SPECTRUM1500107
SPECTRUM1500609
SR 96225
SR-96225
STK361815
SUN-Y4001
Sandesin
Spectrum2_001257
Spectrum2_001336
Spectrum3_000288
Spectrum3_000580
Spectrum4_000782
Spectrum5_001429
Spectrum_001894
Spongoadenosine
TL8003749
UNII-3XQD2MEW34
UNII-K72T3FS567
USAF CB-10
V0098
VIRDARABINE
Vidarabin
Vidarabina
Vidarabina [DCIT]
Vidarabine
Vidarabine (JAN)
Vidarabine anhydrous
Vidarabinum
Vira ATM
Vira-A
Vira-A, Vidarabine
XA
Xylosyl A
Xylosyladenine
ZINC00970363
ZINC02169830
adenine-D-ribose
adenosine
alpha-Ara A
beta-Adenosine
beta-Ara A
beta-D-Adenosine
bmse000061
nchembio.143-comp9
nchembio.186-comp109
nchembio.64-comp4
nchembio706-5

Interventional clinical trials:

(show all 42)
idNameStatusNCT IDPhase
1Renal Effect of Stribild or Other Tenofovir DF-containing Regimens Compared to Ritonavir-boosted Atazanavir Plus Abacavir/Lamivudine in Antiretroviral Treatment-naive HIV-1 Infected AdultsCompletedNCT02246998Phase 4
2Renoprotective Effects of Dapagliflozin in Type 2 DiabetesRecruitingNCT02682563Phase 4
3Use of Spironolactone for the Prevention of Electrolyte Abnormalities in Patients Treated With Amphotericin BTerminatedNCT01843309Phase 4
4Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure SyndromesCompletedNCT00004787Phase 2
5Sulfamethoxazole for the Treatment of Primary PREPL DeficiencyEnrolling by invitationNCT02640443Phase 2
6A Study of KRN23 in Subjects With Tumor-Induced Osteomalacia or Epidermal Nevus SyndromeNot yet recruitingNCT02722798Phase 2
7Safety and Efficacy Trial of Danazol in Patients With Fanconi Anemia or Dyskeratosis CongenitaTerminatedNCT01001598Phase 1, Phase 2
8Pilot Study of Mycophenolate Mofetil in Congenital UropathiesCompletedNCT00193635Phase 1
9Quercetin in Children With Fanconi Anemia; a Pilot StudyRecruitingNCT01720147Phase 1
10Abatacept Reduced Intensity for Non-Malignant DiseasesRecruitingNCT01917708Phase 1
11Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed by Unrelated Donor Stem Cell Transplant in Treating Patients With Fanconi AnemiaActive, not recruitingNCT00093743Phase 1
12Use of Rft5-Dga to Deplete Alloreactive Cells for Pts With Fanconi Anemia After Haploidentical SCTTerminatedNCT00586274Phase 1
13Dismembered Pyeloplasty With and Without After Coming StentCompletedNCT02138877
14The Efficacy and Safety of Local Anesthetic Infusion With RopivacaineCompletedNCT00930046
15Severe Impairment of Solute-Free Water Clearance in Patients With HIV InfectionCompletedNCT01869010
16Study of the Pathophysiological Mechanisms Involved in Bleeding EventsCompletedNCT01314560
17Assessment and Monitoring of Renal Proximal Tubular Tolerance of Nucleoside and Nucleotide Analogues Using Early Screening Tools in Patients Chronically Mono-infected With Hepatitis B VirusCompletedNCT01500265
18Cardiovascular Evaluation of Adult PHA 1 PatientsCompletedNCT00646828
19Genetic Analysis of Oculocerebrorenal Syndrome of LoweCompletedNCT00359515
20Pilot Study of Etanercept (Enbrel) in Children With Fanconi AnemiaCompletedNCT00965666
21Assessing Immune Function in Young Patients With Cytopenia That Did Not Respond to TreatmentCompletedNCT00499070
22Indwelling Double-J Ureteral Stent Versus Externalized Modified-Salle Stent for PyeloplastyRecruitingNCT02713633
23Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract TumorsRecruitingNCT02276924
24Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent RemovalRecruitingNCT02140970
25The Correlation Between Renal Injury and Biomarkers in Pediatric Ureteropelvic Junction Obstruction PatientsRecruitingNCT01711996
26Clinical and Molecular Investigations Into CiliopathiesRecruitingNCT00068224
27Clinical Observation on Bone Metabolism Induced by Chronic Renal InsufficiencyRecruitingNCT02147782
28Metabolic Screening in Patients With Donnai-Barrow SyndromeRecruitingNCT01509287
29Prospective Research Rare Kidney Stones (ProRKS)RecruitingNCT02780297
30Investigation of the Genetics of Hematologic DiseasesRecruitingNCT02720679
31Long Term Outcome of Congenital Solitary KidneyRecruitingNCT01831141
32Research Network for Neonatal Diseases Induced by Tissular Fetomaternal AlloimmunizationRecruitingNCT00199628
33Amniotic Biomarkers in the Prediction of Postpartum Renal Function.Active, not recruitingNCT02675686
34Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure DisordersActive, not recruitingNCT00856388
35Rare Genetic Disorders of the Breathing AirwaysActive, not recruitingNCT00323167
36Ambulatory Blood Pressure Measurement in Children With Congenital Urine Flow ObstructionAvailableNCT00764543
37Use Massive Parallel Sequencing and Exome Capture Technology to Sequence the Exome of Fanconi Anemia Children and Their PatentsAvailableNCT01995305
38Ureteropelvic Junction Obstruction in Early Childhood: Comparison of Surgical Therapy and Surveillance. A Prospective, Randomized, Controlled Multi-Center StudyNot yet recruitingNCT00444431
39PREPL in Health and DiseaseNot yet recruitingNCT02263781
40Alefacept and Allogeneic Hematopoietic Stem Cell TransplantationSuspendedNCT01319851
41Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic CancerTerminatedNCT00290628
42Tc-99m Renography and Cisplatin-induced NephrotoxicityTerminatedNCT00213642

Search NIH Clinical Center for Renal Tubular Dysgenesis

Genetic Tests for Renal Tubular Dysgenesis

About this section

Anatomical Context for Renal Tubular Dysgenesis

About this section

MalaCards organs/tissues related to Renal Tubular Dysgenesis:

33
Kidney, Bone, Lung, Bone marrow, Liver, Prostate, Ovary

Animal Models for Renal Tubular Dysgenesis or affiliated genes

About this section

MGI Mouse Phenotypes related to Renal Tubular Dysgenesis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.7ACE, AGT, AGTR1
2MP:00053868.2ACE, AGT, AGTR1, REN
3MP:00053678.1ACE, AGT, AGTR1, REN
4MP:00053878.0ACE, AGT, AGTR1, REN
5MP:00053857.7ACE, AGT, AGTR1, REN

Publications for Renal Tubular Dysgenesis

About this section

Articles related to Renal Tubular Dysgenesis:

(show top 50)    (show all 58)
idTitleAuthorsYear
1
Renal function in angiotensinogen gene-mutated renal tubular dysgenesis with glomerular cysts. (25414114)
2015
2
Successful treatment of hemochromatosis with renal tubular dysgenesis in a preterm infant. (26331014)
2015
3
Renal tubular dysgenesis. (23636579)
2014
4
Spectrum of mutations in the renin-angiotensin system genes in autosomal recessive renal tubular dysgenesis. (22095942)
2012
5
Survival over 2 years of autosomal-recessive renal tubular dysgenesis. (26069751)
2012
6
Renal tubular dysgenesis and reversible hypocalvaria after intrauterine exposure to an angiotensin receptor blocker. (25984140)
2011
7
Impaired proteostasis contributes to renal tubular dysgenesis. (21695262)
2011
8
Renal tubular dysgenesis and tubulointerstitial nephritis antigen in juvenile nephronophthisis. (21265929)
2011
9
Renin-angiotensin system in kidney development: renal tubular dysgenesis. (19924102)
2010
10
Non-specific histopathological changes in kidney with renal tubular dysgenesis. (19616900)
2010
11
Inherited renal tubular dysgenesis may not be universally fatal. (20607303)
2010
12
Relationship of proximal renal tubular dysgenesis and fetal liver injury in neonatal hemochromatosis. (19809376)
2010
13
A further case of renal tubular dysgenesis surviving the neonatal period. (18478260)
2009
14
Congenital unilateral renal tubular dysgenesis and severe neonatal hypertension. (18982358)
2009
15
Renal tubular dysgenesis in Israel: pathologist's experience and literature review. (19344005)
2009
16
Inherited renal tubular dysgenesis: the first patients surviving the neonatal period. (17443344)
2008
17
A case surviving for over a year of renal tubular dysgenesis with compound heterozygous angiotensinogen gene mutations. (17036344)
2006
18
Renal tubular dysgenesis with atypical histology and in-utero exposure to naproxen sodium. (16925962)
2006
19
Renal tubular dysgenesis associated with in utero exposure to Nimuselide. (16328538)
2006
20
Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis. (16116425)
2005
21
Renal tubular dysgenesis with hypoplastic calvaria: report of two cases. (15517826)
2004
22
Renal tubular dysgenesis-a case presentation. (15641273)
2004
23
Renal tubular dysgenesis and neonatal hemochromatosis without pulmonary hypoplasia. (14677054)
2004
24
Renal tubular dysgenesis complicated with severe cranium hypoplasia. (15043673)
2004
25
Renal tubular dysgenesis. (12908566)
2003
26
Renal tubular dysgenesis in an hydropic fetus with trisomy 21: a case report with literature review. (15018458)
2003
27
Renal tubular dysgenesis and multiple intestinal perforation. (12447649)
2003
28
Renal tubular dysgenesis in siblings. (12908573)
2003
29
Fibroepithelial bladder polyp and renal tubular dysgenesis: an unusual cause of third-trimester oligohydramnios. (11549150)
2001
30
Lysozyme immunostaining in renal tubular dysgenesis. (10679040)
2000
31
Renal tubular dysgenesis-like lesions and hypocalvaria. Report of two cases involving indomethacin. (11186177)
2000
32
Oxalate nephrocalcinosis in renal tubular dysgenesis. (10671031)
1999
33
Renal tubular dysgenesis in twin-twin transfusion syndrome. (9841703)
1999
34
Renal tubular dysgenesis, absent nipples, and multiple malformations in three brothers: a new, lethal syndrome. (9856560)
1998
35
Renal tubular dysgenesis in twins. (9686962)
1998
36
Renal tubular dysgenesis with calvarial hypoplasia: report of two additional cases and review. (9350819)
1997
37
Renal tubular dysgenesis: a cause of second trimester oligohydramnios. (9321784)
1997
38
Renal tubular dysgenesis with microcephaly. (9260254)
1997
39
Renal tubular dysgenesis: a report of two cases. (8979193)
1996
40
Familial renal tubular dysgenesis: a disorder not isolated to proximal convoluted tubules. (8705201)
1995
41
Renal tubular dysgenesis without pulmonary hypoplasia. (8018503)
1994
42
Labeled lectin studies of renal tubular dysgenesis and renal tubular atrophy of postnatal renal ischemia and end-stage kidney disease. (8159624)
1994
43
Renal tubular dysgenesis: evidence of abnormality in the renin-angiotensin system. (7994002)
1994
44
Renal tubular dysgenesis. (8160762)
1994
45
Renal tubular dysgenesis: a description of early renal maldevelopment in siblings. (8464784)
1993
46
Renal tubular dysgenesis: a not uncommon autosomal recessive syndrome: a review. (1642268)
1992
47
Renal tubular dysgenesis. (1853827)
1991
48
Renal tubular dysgenesis and very large cranial fontanels in a family with acrocephalosyndactyly S.C. type. (1877630)
1991
49
Renal tubular dysgenesis: delayed onset of oligohydramnios. (2650547)
1989
50
Renal tubular dysgenesis. (3211817)
1988

Variations for Renal Tubular Dysgenesis

About this section

UniProtKB/Swiss-Prot genetic disease variations for Renal Tubular Dysgenesis:

67
id Symbol AA change Variation ID SNP ID
1AGTp.Arg375GlnVAR_035433
2AGTR1p.Thr282MetVAR_035086
3RENp.Arg230LysVAR_035087
4RENp.Asp104AsnVAR_035088

Clinvar genetic disease variations for Renal Tubular Dysgenesis:

5 (show all 16)
id Gene Variation Type Significance SNP ID Assembly Location
1RENNM_000537.3(REN): c.145C> T (p.Arg49Ter)single nucleotide variantPathogenicrs121917741GRCh37Chr 1, 204131245: 204131245
2RENNM_000537.3(REN): c.689G> A (p.Arg230Lys)single nucleotide variantPathogenicrs121917742GRCh37Chr 1, 204128527: 204128527
3ACENM_000789.3(ACE): c.798C> G (p.Tyr266Ter)single nucleotide variantPathogenicrs121912704GRCh37Chr 17, 61557840: 61557840
4ACENM_000789.3(ACE): c.1319_1322delTGGA (p.Leu440Profs)deletionPathogenicrs387906576GRCh37Chr 17, 61560027: 61560030
5AGTR1NM_031850.3(AGTR1): c.215dupT (p.Ile73Hisfs)duplicationPathogenicrs387906577GRCh37Chr 3, 148458932: 148458932
6AGTR1NM_031850.3(AGTR1): c.950C> T (p.Thr317Met)single nucleotide variantPathogenicrs104893677GRCh37Chr 3, 148459667: 148459667
7AGTNM_000029.3(AGT): c.1124G> A (p.Arg375Gln)single nucleotide variantPathogenicrs74315283GRCh37Chr 1, 230841679: 230841679
8AGTNM_000029.3(AGT): c.604C> T (p.Gln202Ter)single nucleotide variantPathogenicrs121912702GRCh37Chr 1, 230845993: 230845993
9AGTNM_000029.3(AGT): c.1290delT (p.Phe430Leufs)deletionPathogenicrs387906578GRCh37Chr 1, 230839055: 230839055
10ACENM_000789.3(ACE): c.12_31del20 (p.Ser5Alafs)deletionPathogenicrs797045079GRCh38Chr 17, 63477106: 63477125
11AGTR1NM_031850.3(AGTR1): c.356G> A (p.Trp119Ter)single nucleotide variantPathogenicrs398122935GRCh37Chr 3, 148459073: 148459073
12AGTR1NM_031850.3(AGTR1): c.481C> T (p.Arg161Ter)single nucleotide variantPathogenicrs397514687GRCh37Chr 3, 148459198: 148459198
13ACENM_000789.3(ACE): c.1486C> T (p.Arg496Ter)single nucleotide variantPathogenicrs397514688GRCh37Chr 17, 61560533: 61560533
14ACENM_000789.3(ACE): c.2371C> T (p.Arg791Ter)single nucleotide variantPathogenicrs397514689GRCh37Chr 17, 61566074: 61566074
15RENNM_000537.3(REN): c.127C> T (p.Arg43Ter)single nucleotide variantPathogenicrs397514690GRCh37Chr 1, 204131263: 204131263
16RENNM_000537.3(REN): c.404C> A (p.Ser135Tyr)single nucleotide variantPathogenicrs397514691GRCh37Chr 1, 204129776: 204129776

Expression for genes affiliated with Renal Tubular Dysgenesis

About this section
Search GEO for disease gene expression data for Renal Tubular Dysgenesis.

Pathways for genes affiliated with Renal Tubular Dysgenesis

About this section

GO Terms for genes affiliated with Renal Tubular Dysgenesis

About this section

Biological processes related to Renal Tubular Dysgenesis according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1regulation of renal output by angiotensinGO:000201910.0ACE, AGT
2renin-angiotensin regulation of aldosterone productionGO:00020189.9AGT, REN
3blood vessel remodelingGO:00019749.9ACE, AGT
4regulation of blood volume by renin-angiotensinGO:00020169.8AGT, REN
5regulation of blood vessel size by renin-angiotensinGO:00020349.8AGT, AGTR1
6positive regulation of cholesterol esterificationGO:00108739.7AGT, AGTR1
7positive regulation of cellular protein metabolic processGO:00322709.6AGT, AGTR1
8positive regulation of macrophage derived foam cell differentiationGO:00107449.6AGT, AGTR1
9kidney developmentGO:00018229.5AGT, REN
10positive regulation of reactive oxygen species metabolic processGO:20003799.4AGT, AGTR1
11phospholipase C-activating G-protein coupled receptor signaling pathwayGO:00072009.3AGT, AGTR1
12proteolysisGO:00065089.2ACE, REN
13positive regulation of inflammatory responseGO:00507299.1AGT, AGTR1
14regulation of cell proliferationGO:00421279.1AGT, AGTR1
15regulation of vasoconstrictionGO:00192298.3ACE, AGT, AGTR1

Sources for Renal Tubular Dysgenesis

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet