MCID: RNL022
MIFTS: 35

Renal Vascular Disease malady

Summaries for Renal Vascular Disease

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33MalaCards
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MalaCards: Renal Vascular Disease, also known as vascular disorder of kidney, is related to vascular disease and peripheral vascular disease. An important gene associated with Renal Vascular Disease is MPV17 (MpV17 mitochondrial inner membrane protein), and among its related pathways is A-beta Uptake & Degradation. The compounds oxygen and captopril have been mentioned in the context of this disorder. Related mouse phenotypes are renal/urinary system and growth/size.

Aliases & Classifications for Renal Vascular Disease

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 40NCIt, 27ICD9CM
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Aliases & Descriptions:

renal vascular disease 8 10
vascular disorder of kidney 8
renal vascular disorder 61


External Ids:

Disease Ontology8 DOID:2388
NCIt40 C35338
ICD9CM27 593.81

Related Diseases for Renal Vascular Disease

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Renal Vascular Disease:



Diseases related to renal vascular disease

Clinical Features for Renal Vascular Disease

Drugs & Therapeutics for Renal Vascular Disease

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Renal Vascular Disease

Drug clinical trials:

Search ClinicalTrials for Renal Vascular Disease

Search NIH Clinical Center for Renal Vascular Disease

Search CenterWatch for Renal Vascular Disease

Genetic Tests for Renal Vascular Disease

Anatomical Context for Renal Vascular Disease

Animal Models for Renal Vascular Disease or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Renal Vascular Disease:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053677.5AGER, VEGFA, ACE, ALB, MPV17
2MP:00053787.3ACE, HSPD1, CTGF, FBXL20, MPV17, AGER
3MP:00107686.9FBXL20, CTGF, HSPD1, MPV17, ACE, ALB

Publications for Renal Vascular Disease

Sources:
51PubMed
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Articles related to Renal Vascular Disease:

(show top 50)    (show all 123)
idTitleAuthorsYear
1
Five-year decline in estimated glomerular filtration rate associated with a higher risk of renal disease and atherosclerotic vascular disease clinical events in elderly women. (23407347)
2013
2
Are kidneys not ischemic in human renal vascular disease? (20194299)
2010
3
Vascular calcification and metabolic acidosis in end stage renal disease. (19918300)
2009
4
Two cases of silent superior vena cava syndrome associated with vascular access and end-stage renal disease. (20037893)
2009
5
Comparison of renal and vascular protective effects between telmisartan and amlodipine in hypertensive patients with chronic kidney disease with mild renal insufficiency. (18712038)
2008
6
Interaction of vascular and bone disease in patients with normal renal function and patients undergoing dialysis. (17180147)
2007
7
Asymmetric dimethylarginine (ADMA) in vascular, renal and hepatic disease and the regulatory role of L-arginine on its metabolism. (17560156)
2007
8
Controversial treatment of atherosclerotic renal vascular disease: the cardiovascular outcomes in renal atherosclerotic lesions trial. (16864748)
2006
9
Renal vascular disease in neurofibromatosis type 2: association or coincidence? (16359595)
2006
10
Vascular calcification in patients with end-stage renal disease. (15284362)
2004
11
Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease. (12709399)
2004
12
Bivalirudin as a foundation anticoagulant in peripheral vascular disease: a safe and feasible alternative for renal and iliac interventions. (12777673)
2003
13
The importance of associated extra-renal vascular disease on the outcome of patients with atherosclerotic renovascular disease. (12616031)
2003
14
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 37-2003. A 79-year-old man with coronary artery disease, peripheral vascular disease, end-stage renal disease, and abdominal pain and distention. (14645643)
2003
15
Management of renal vascular disease in neurofibromatosis type 1 and the role of percutaneous transluminal angioplasty. (12105246)
2002
16
Prospective multicentre study of the natural history of atherosclerotic renal artery stenosis in patients with peripheral vascular disease. (12027983)
2002
17
Peripheral vascular disease in end-stage renal disease patients. (12518956)
2002
18
Incidental renal artery stenosis in peripheral vascular disease: a case for treatment? (11260411)
2001
19
Severity of renal vascular disease predicts mortality in patients undergoing coronary angiography. (11576364)
2001
20
Peripheral vascular disease and renal transplant artery stenosis: a reappraisal of transplant renovascular disease. (10485378)
1999
21
The role of hypertension, obesity, and diabetes in causing renal vascular disease. (10100692)
1999
22
Diagnostic testing in vascular medicine: the foundation for successful intervention II--renal and abdominal aortic disease. (10745481)
1999
23
Renal vascular disease in the elderly. (9839288)
1998
24
Different patterns of endothelial cell activation in renal and pulmonary vascular disease in scleroderma. (9893759)
1998
25
Survival in renal vascular disease. (9527401)
1998
26
Prevalence of renal artery stenosis in patients with peripheral vascular disease and hypertension. (8867560)
1996
27
Expression of receptors for advanced glycation end-products in occlusive vascular and renal disease. (9044315)
1996
28
Renal vascular disease as a cause of hypertension. (7743162)
1995
29
Evaluation and management of atherosclerotic renal vascular disease to prevent end-stage renal failure. (8059189)
1994
30
Progression of occlusive renal vascular disease and axillofemoral bypass grafts. (8272243)
1993
31
Vascular adventitial cell expression of collagen I messenger ribonucleic acid in anti-glomerular basement membrane antibody-induced crescentic nephritis in the rabbit. A cellular source for interstitial collagen synthesis in inflammatory renal disease. (8497127)
1993
32
Albuminuria--a marker of renal and generalized vascular disease in insulin-dependent diabetes mellitus. (2060321)
1991
33
Renal vascular disease in African-Americans and other racial minorities. (2013172)
1991
34
Diagnosis and treatment of renal vascular disease. (2300217)
1990
35
Evaluation of mesenteric and renal vascular disease. (2182093)
1990
36
Aortic and renal vascular disease. Factors affecting the value of combined procedures. (6465984)
1984
37
Symposium on renal vascular disease. (6464246)
1984
38
Influence of neonatal thymectomy on blood pressure and hypertensive vascular disease in rats with renal hypertension. (1096529)
1975
39
Hypertension due to unilateral renal vascular disease. (4959458)
1966
40
THE PHONORENOGRAM: TRANSURETERAL PHONOCATHETER RECORDING OF THE RENAL ARTERY PULSE IN THE DIAGNOSIS OF RENAL VASCULAR DISEASE. (14226461)
1964
41
HYPERTENSION DUE TO UNILATERAL RENAL VASCULAR DISEASE. (14228117)
1964
42
THE ROLE OF THE RENIN-ANGIOTENSIN SYSTEM IN THE HYPERTENSION ASSOCIATED WITH RENAL VASCULAR DISEASE. (14111735)
1964
43
RENAL VASCULAR DISEASE. (14328536)
1964
44
Differential excretion studies in the evaluation of unilateral renal vascular disease. (13881077)
1962
45
Renal-vascular disease as a cause of hypertension. Selection of patients for aortographic studies. (14023143)
1962
46
Diagnosis of renal vascular disease and renal tumors by photoscanning. (13905680)
1962
47
Diagnosis of renal vascular disease. (14476244)
1962
48
Urinary excretion of 5-hydroxyindole acetic acid, a serotonin metabolite, in hypertensive renal-vascular disease. (13389505)
1956
49
Renal vascular disease a primary basis of essential hypertension. (13084104)
1953
50
Relief of malignant hypertension by nephrectomy in four patients with unilateral renal vascular disease. (13136259)
1953

Genetic Variations for Renal Vascular Disease

Expression for genes affiliated with Renal Vascular Disease

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Renal Vascular Disease

Search GEO for disease gene expression data for Renal Vascular Disease.

Pathways for genes affiliated with Renal Vascular Disease

Sources:
53R&D Systems
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Pathways related to Renal Vascular Disease according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6ACE, AGER

Compounds for genes affiliated with Renal Vascular Disease

Sources:
45Novoseek, 24HMDB, 29IUPHAR, 50PharmGKB, 60Tocris Bioscience, 11DrugBank
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Compounds related to Renal Vascular Disease according to GeneCards/GeneDecks:

(show all 46)
idCompoundScoreTop Affiliating Genes
1oxygen45 2411.5MPV17
2captopril45 29 50 60 1114.5CTGF
3glucose4510.1CTGF, HSPA8
4alpha tocopherol4510.0HSPA8, CTGF
5kallidin45 2911.0ACE, CTGF
6olmesartan45 29 1112.0AGER, ACE
7cdcl2459.9HSPD1, HSPA8
8n(epsilon)-(carboxymethyl)lysine459.7AGER, ALB
9losartan45 50 29 1112.7ALB, CTGF
10pentosidine459.7AGER, ALB
11mannitol45 1110.6ALB, HSPA8
12nifedipine45 50 29 1112.6ACE, AGER, CTGF
13indapamide45 1110.5ACE, ALB
14fosinopril45 1110.5ACE, ALB
15glyceraldehyde 3-phosphate459.5CTGF, HSPD1, HSPA8
16ramipril45 1110.4ALB, ACE
17Vandetanib119.4ALB, VEGFA
18valsartan45 60 29 1112.4ACE, ALB
19ang ii459.4ACE, VEGFA, CTGF
20simvastatin45 50 60 29 11 2414.4HSPA8, CTGF, VEGFA
21irbesartan45 29 50 1112.3ALB, ACE
22curcumin459.3HSPA8, CTGF, VEGFA
23hydrochlorothiazide45 50 29 11 2413.3ALB, ACE
24gliclazide45 50 1111.3ALB, VEGFA
25enalapril45 50 1111.3ACE, ALB
26arsenite45 2410.3VEGFA, HSPD1, HSPA8
27spironolactone50 45 60 29 1113.2ALB, ACE
28ribonucleic acid459.2CTGF, HSPD1, HSPA8
29carvedilol45 50 29 1112.2VEGFA, ACE
30telmisartan45 29 1111.2AGER, ACE, ALB
31amlodipine45 50 11 2412.2ALB, ACE
32heparin45 29 11 2412.1HSPA8, CTGF, AGER, VEGFA
33radicicol45 60 1111.1VEGFA, HSPA8
34prostacyclin459.0CTGF, AGER, VEGFA, ACE
35lisinopril45 11 2410.9VEGFA, ACE, ALB
36perindopril45 50 1110.9VEGFA, ACE, ALB
37imatinib45 50 1110.9ALB, VEGFA, HSPA8
38nitric oxide45 11 2410.8ACE, AGER, CTGF, HSPA8
39lactate458.8HSPA8, HSPD1, CTGF, ALB
40n acetylcysteine458.7VEGFA, AGER, CTGF, HSPD1, HSPA8
41vegf458.7VEGFA, AGER, CTGF, HSPD1, HSPA8
42candesartan45 29 1110.6ALB, ACE, VEGFA, AGER
43cholesterol45 29 11 2411.3HSPA8, HSPD1, AGER, ACE, ALB
44creatinine458.0HSPA8, HSPD1, CTGF, AGER, ACE, ALB
45lipid458.0HSPA8, HSPD1, CTGF, AGER, ACE, ALB
46calcium45 50 11 2410.8HSPA8, HSPD1, CTGF, AGER, ACE, ALB

GO Terms for genes affiliated with Renal Vascular Disease

Sources:
16Gene Ontology
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Cellular components related to Renal Vascular Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055767.8AGER, VEGFA, ACE, ALB, CTGF
2extracellular spaceGO:0056157.4ALB, ACE, VEGFA, CTGF, HSPD1

Biological processes related to Renal Vascular Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1reactive oxygen species metabolic processGO:0725939.8MPV17, CTGF
2induction of positive chemotaxisGO:0509309.2VEGFA, AGER

Molecular functions related to Renal Vascular Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1fibronectin bindingGO:0019689.5VEGFA, CTGF

Products for genes affiliated with Renal Vascular Disease

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Renal Vascular Disease

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet