MCID: RPR002
MIFTS: 43

Reproductive System Disease

Categories: Reproductive diseases

Aliases & Classifications for Reproductive System Disease

MalaCards integrated aliases for Reproductive System Disease:

Name: Reproductive System Disease 12 14
Abnormality of the Genital System 29
Reproductive System Disorder 69
Genital System Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:15
NCIt 47 C27613
UMLS 69 C1335037

Summaries for Reproductive System Disease

Disease Ontology : 12 A disease of anatomical entity that is located in reproductive system organs.

MalaCards based summary : Reproductive System Disease, also known as abnormality of the genital system, is related to endometriosis and male reproductive system disease. An important gene associated with Reproductive System Disease is AMH (Anti-Mullerian Hormone), and among its related pathways/superpathways are Ovarian steroidogenesis and Follicle Stimulating Hormone (FSH) signaling pathway. The drugs Aripiprazole and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include prostate, ovary and bone, and related phenotypes are endocrine/exocrine gland and reproductive system

Wikipedia : 72 A reproductive system disease is any disease of the reproductive... more...

Related Diseases for Reproductive System Disease

Diseases related to Reproductive System Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
id Related Disease Score Top Affiliating Genes
1 endometriosis 32.3 KLK3 PRL SHBG
2 male reproductive system disease 12.2
3 female reproductive system disease 12.2
4 10q22.3q23 microdeletion syndrome 11.1 DAZ1 DAZL
5 passos-bueno syndrome 11.0 DAZ1 DAZ4
6 african histoplasmosis 11.0 GNRH1 PRL
7 retinitis pigmentosa, y-linked 11.0 DAZ1 DAZ4
8 thymus mucoepidermoid carcinoma 11.0 AMH BMP15 GNRH1
9 prostate leiomyoma 10.9 GNRH1 PRL
10 polyneuropathy 10.9 CYP19A1 SHBG
11 gastrointestinal tularemia 10.9 DAZ1 DAZ4 PRL
12 precocious puberty, male 10.9 CYP19A1 FSHR
13 uterine corpus adenocarcinofibroma 10.9 GNRH1 PRL SHBG
14 adenomatoid tumor 10.9 GNRH1 PRL
15 mitochondrial complex iii deficiency, nuclear type 9 10.9 BMP15 CYP19A1
16 haverhill fever 10.9 CYP19A1 GNRH1 PRL
17 acute thyroiditis 10.9 CYP19A1 FSHR SHBG
18 munchausen by proxy 10.9 KLK3 PRL SHBG
19 retroperitoneal sarcoma 10.9 AMH GNRH1 PRL SHBG
20 capillary lymphangioma 10.9 AMH FSHR GNRH1 SHBG
21 osteopathia striata with cranial sclerosis 10.9 CYP19A1 SHBG
22 ovarian hyperstimulation syndrome 10.8 AMH CYP19A1 FSHR GNRH1
23 intermittent squint 10.8 GNRH1 PRL
24 spermatogenic failure, y-linked, 1 10.8 BMP15 FSHR
25 viral hepatitis 10.8 KLK3 PRL SHBG
26 46 xx gonadal dysgenesis 10.8 AMH BMP15 FSHR GDF9
27 survival motor neuron spinal muscular atrophy 10.8 PRL SHBG TRPV1
28 plague 10.8 KLK3 PRL SHBG
29 lymphoepithelioma-like carcinoma 10.8 GNRH1 PRL
30 pelvic muscle wasting 10.8 CYP19A1 GNRH1 PRL SHBG
31 diabetes mellitus, insulin-resistant, with acanthosis nigricans 10.8 AMH DAZ1 DAZ4 GNRH1 SHBG
32 brown-vialetto-van laere syndrome 10.8 AREG KLK3 TRPV1
33 glioblastoma proneural subtype 10.8 CYP19A1 KLK3 PRL SHBG
34 capillary disease 10.8 CYP19A1 KLK3 PRL SHBG
35 sphingolipidosis 10.7 AMH CYP19A1 GNRH1 PRL SHBG
36 spondylosis 10.7 PRL SHBG TRPV1
37 hole retinal cyst 10.7 GNRH1 KLK3
38 acute gonococcal salpingitis 10.7 BMP15 FSHR GNRH1 PRL SHBG
39 vertebral artery occlusion 10.7 GNRH1 PRL
40 uterine disease 10.7
41 aromatase excess syndrome 10.7
42 ectopic pregnancy 10.7
43 medullomyoblastoma 10.7 AREG GNRH1 KLK3 SHBG TRPV1
44 lactic acidosis 10.7 GNRH1 PRL
45 perinatal jaundice due to hepatocellular damage 10.6 AMH CYP19A1
46 mannosidosis 10.6 DAZ1 DAZ4 DAZL FSHR PRM1 PRM2
47 porokeratosis 10.6 BMP15 CYP19A1 FSHR GNRH1 PRL SHBG
48 precursor b lymphoblastic lymphoma/leukemia 10.6 CYP19A1 FSHR GDF9 GNRH1 PRL SHBG
49 internal hemorrhoid 10.6 DPY19L2 GNRH1 PRL PRM1 PRM2 SHBG
50 epilepsy, idiopathic generalized 11 10.5 CYP19A1 SHBG

Graphical network of the top 20 diseases related to Reproductive System Disease:



Diseases related to Reproductive System Disease

Symptoms & Phenotypes for Reproductive System Disease

MGI Mouse Phenotypes related to Reproductive System Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.65 CYP19A1 DPY19L2 FSHR GDF9 GNRH1 PRL
2 reproductive system MP:0005389 9.32 AMH AREG BMP15 CYP19A1 DPY19L2 FSHR

Drugs & Therapeutics for Reproductive System Disease

Drugs for Reproductive System Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1500)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
2
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-61-6, 62-31-7 681
3
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
4
Povidone Approved Phase 4,Phase 3 9003-39-8
5 Povidone-iodine Approved Phase 4,Phase 3 25655-41-8
6
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-84-3 187
7
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 657-24-9 14219 4091
8
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 18323-44-9 29029
9
Selenium Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 7782-49-2
10
Methyltestosterone Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-18-4 6010
11
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-22-0 6013
12
Ritonavir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 155213-67-5 392622
13
Acetylcysteine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 616-91-1 12035
14
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 443-48-1 4173
15
Desogestrel Approved Phase 4,Phase 3,Phase 2 54024-22-5 40973
16
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-28-2 5757
17
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 57-63-6 5991
18
Etonogestrel Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 54048-10-1 40976 6917715
19
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-02-2 5743
20
Diazepam Approved, Illicit, Vet_approved Phase 4,Phase 3 439-14-5 3016
21
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 437-38-7 3345
22
Meperidine Approved Phase 4,Phase 1 57-42-1 4058
23
Midazolam Approved, Illicit Phase 4,Phase 2,Phase 3,Phase 1 59467-70-8 4192
24
Ganirelix Approved Phase 4,Phase 3,Phase 2,Early Phase 1 123246-29-7, 124904-93-4 25081094
25
Cetrorelix Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 120287-85-6 16129715 25074887
26
Letrozole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 112809-51-5 3902
27
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 57-83-0 5994
28
Leuprolide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 53714-56-0 3911 657181
29
Calcium Carbonate Approved Phase 4,Phase 3,Phase 1 471-34-1
30
Goserelin Approved Phase 4,Phase 3,Phase 2,Phase 1 65807-02-5 47725 5311128
31
Tibolone Approved Phase 4 5630-53-5
32
Cyproterone Acetate Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 427-51-0
33
Tamsulosin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 106133-20-4 129211
34
Tadalafil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 171596-29-5 110635
35
Azithromycin Approved Phase 4,Phase 3,Phase 2,Phase 1 83905-01-5 55185 53477736 447043
36
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 564-25-0 54671203
37
Lymecycline Approved Phase 4 992-21-2 5280963
38
Tetracycline Approved, Vet_approved Phase 4,Phase 3,Early Phase 1 60-54-8 5353990
39
Bupivacaine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 2180-92-9, 38396-39-3 2474
40
Dutasteride Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 164656-23-9 152945 6918296
41
Finasteride Approved Phase 4,Phase 3,Phase 2,Phase 1 98319-26-7 57363
42
Levonorgestrel Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 797-63-7, 17489-40-6 13109
43
Medroxyprogesterone acetate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 71-58-9
44
Terbutaline Approved Phase 4,Phase 3,Phase 2,Phase 1 23031-25-6 5403
45
Nebivolol Approved, Investigational Phase 4,Phase 1 152520-56-4, 99200-09-6, 118457-14-0 71301
46
Clonidine Approved Phase 4,Phase 3,Phase 2,Phase 1 4205-90-7 2803
47
Norethindrone Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 68-22-4 6230
48
Drospirenone Approved Phase 4,Phase 3,Phase 1,Early Phase 1 67392-87-4 68873
49
Hydroxychloroquine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 118-42-3 3652
50
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1 170277-31-3

Interventional clinical trials:

(show top 50) (show all 9380)

id Name Status NCT ID Phase Drugs
1 A Multicenter Study to Evaluate the Effects of Switching to Aripiprazole 12 Weeks on the Sexual Dysfunction From Risperidone or Paliperidone in Patients With Schizophrenia Spectrum Disorders or Bipolar Spectrum Disorders Unknown status NCT01742390 Phase 4 Aripiprazole;risperidone or paliperidone
2 National,Multicentric Randomised Study of the Correction of Genital Prolapse With Fascial Repair or Mesh-Prolift Unknown status NCT00771225 Phase 4
3 Effect of Fluticasone Proprionate 0.05% on Narrow Band UV-B in Active Vitiligo Unknown status NCT01246921 Phase 4 Fluticasone proprionate 0.05% cream
4 Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism Unknown status NCT02140515 Phase 4 Lutropin alfa;Follitropin alfa and Lutropin alfa
5 Functional Outcome After Groin Hernia Mesh Repair: Open Versus Laparoscopy Unknown status NCT00625534 Phase 4
6 A Prospective Trial of Povidone-iodine Suppository Before Transrectal Ultrasound Guided Prostate Biopsy Unknown status NCT02245334 Phase 4 Povidone-Iodine
7 Botox on Vulvar Vestibulitis Unknown status NCT00119886 Phase 4 Botulinum toxin
8 Myoinositol for the Treatment of Ovarian and Psychiatric Disorder in Polycystic Ovary Syndrome (PCOS) Patients Unknown status NCT01246310 Phase 4
9 Metformin for the Treatment of Unexplained Oligozspermia Unknown status NCT01529177 Phase 4 Metformin / clomid / hCG;Clomiphene citrate / hCG
10 Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China Unknown status NCT01021904 Phase 4
11 Compare Sacrospinous Fixation Versus High Uterosacral Ligament Fixation for Uterus Vaginal Prolapse III/IV Unknown status NCT01347021 Phase 4
12 Probiotic Versus Placebo as Adjuvant for Bacterial Vaginosis Treatment During Pregnancy Unknown status NCT01558388 Phase 4 Lactobacillus acidophilus;Placebo
13 Selenium Supplementation in Pregnancy Unknown status NCT01465867 Phase 4
14 Assessment of the Effectiveness of a Program of Preparation to Pregnancy and Delivery Unknown status NCT01155804 Phase 4
15 Testosterone Patch's Effects on the Cardiovascular System and Libido Unknown status NCT01208038 Phase 4 Intrinsa Transdermal testosterone patch
16 Efficacy and Safety of Pulsatile Gonadotropin Releasing Hormone Pump Treatment in Patients With Idiopathic Hypogonadotropic Hypogonadism Unknown status NCT02310074 Phase 4 Pulsatile Gonadotropin Releasing Hormone;Human chorionic gonadotropin;Urinary Follicle-Stimulating Hormone
17 Protease Inhibitor Monotherapy Versus Ongoing Triple-therapy in the Long Term Management of HIV Infection (PIVOT) Unknown status NCT01230580 Phase 4 Protease Inhibitor;Standard-of-care Antiretroviral therapy
18 Treatment of Infertility by Collagen Scaffold Loaded With Autologous Bone Marrow Stem Cells Unknown status NCT02204358 Phase 4
19 Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis Unknown status NCT01841411 Phase 4 N-Acetyl cysteine;Metronidazole + N-Acetyl cysteine;metronidazole
20 Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers Unknown status NCT01448291 Phase 4 Etonogestrel /Ethinyl Estradiol Contraceptive Vaginal Ring
21 Probiotics Capsule as Supplemental Therapy for Group B Streptococci Infection and Vaginitis During Pregnancy Unknown status NCT01779193 Phase 4
22 Continuous Postoperative Use of Low-Dose Combined Oral Contraceptivesfor for Endometriosis-Related Chronic Pelvic Pain Unknown status NCT00844012 Phase 4 Continuous OC (clormadinone acetate plus ethinil-estradiol - Belara®, Grunenthal, Milan, Italy);Cyclic OC (clormadinone acetate plus ethinil-estradiol)
23 Ovarian Stimulation: Inositol and Melatonin Unknown status NCT01267604 Phase 4 Recombinant FSH (rFSH)
24 Ovulation Induction With Clomiphene Citrate and Dexamethasone Unknown status NCT01856062 Phase 4 Placebo;Dexamethasone
25 Biosimilar Versus Urinary Gonadotropins Unknown status NCT02503605 Phase 4 Biosimilar recombinant FSH;Urinary FSH
26 A Non-inferiority Trial on Pain Relief During Oocyte Retrieval Unknown status NCT02494180 Phase 4 fentanyl;pethidine;Diazepam;Midazolam
27 Corifollitropin Alfa Versus Follitropin Beta in High Responders Unknown status NCT02471677 Phase 4 Elonva;Puregon
28 Type of Gonadotropin and Embryo Kinetics of Development Unknown status NCT02402192 Phase 4 Corifollitropin alfa
29 Intrauterine Injection of Human Chorionic Gonadotropin Before Embryo Transfer in Women With Previous IVF Failure Unknown status NCT02329197 Phase 4 Human Chorionic Gonadotropin (HCG)
30 Use of Corifolitropin Alfa in Oocyte Donors Unknown status NCT02213627 Phase 4 Corifollitropin alfa;Recombinant FSH;HP-hMG
31 Long Acting FSH Plus Antagonist Versus Daily FSH Plus Antagonist Versus Short Agonist Protocol in Poor Responders Undergoing IVF Unknown status NCT02070198 Phase 4 Long acting FSH and GnRH antagonist;Daily FSH and GnRH antagonist;Triptorelin and recombinant FSH
32 IUI vs. IVF/ICSI in Women Aged 38-42 Years: a Prospective Randomized Controlled Trial. Unknown status NCT01992731 Phase 4
33 Comparison of Ovarian Mild Stimulation and Controlled Ovarian Stimulation in Poor Ovarian Responders Unknown status NCT01926210 Phase 4
34 Physical Activity and ARTs Unknown status NCT01892111 Phase 4
35 Intrauterine Insemination and Luteal Fase Support Unknown status NCT01826747 Phase 4 crinone (progesterone 8%, vaginal application)
36 Study of Dual Trigger Ovulation in Oocyte Donors Unknown status NCT01443546 Phase 4 HCG;Lupron Trigger;Dual Trigger
37 Metformin in Step-down Regimen Versus Conventional Low Dose Step-up Protocol in Patients With PCOS Undergoing IVF Unknown status NCT01438190 Phase 4 Metformin, gonadotropins in step-down regimen;Placebo, gonadotropins in step-up regimen
38 Comparison Between Natural and Artificial Cycle in Recipient Oocyte Patients Unknown status NCT01353846 Phase 4 Agonist GnRH; estradiol Valerate; progesterone
39 Luteal Phase Support With Progesterone Versus Estrogen and Progesterone on Pregnancy Rates Unknown status NCT01237535 Phase 4 Luteal support with progesterone only;Luteal support with estrogen + progesterone
40 Comparison of the Long GnRH Agonist Protocol and the Flexible GnRH Antagonist Protocol of Ovarian Stimulation Unknown status NCT00417183 Phase 4 Arvekap 0.1 mg (Triptorelin, Ipsen, France);Ganirelix 0.25 (Orgalutran, Organon, The Netherlands)
41 Comparison Between hCG and GnRH Agonist for Ovulation Induction in Patients With High Response to IVF Drugs Unknown status NCT00415792 Phase 4 Arvekap, Pregnyl
42 The Effect of LH-Priming During Early Follicular Phase in IVF Treatment. Unknown status NCT00334425 Phase 4 MENOPUR; GONAL-F
43 Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls? Unknown status NCT01101750 Phase 4
44 Randomized Study of Gonadotropin-releasing-hormone Agonist (GnRH-a) or Expectant Management for Endometriosis Unknown status NCT00654524 Phase 4 gonadotropin-releasing-hormone agonist (GnRHa) - Goserelin
45 the Effect of Diane-35 Pretreatment on In-vitro Fertilization Outcome for Patients With Polycystic Ovary Syndrome Unknown status NCT01752270 Phase 4 Diane-35 pretreatment;Diane-35 pretreatment
46 Correlation Among Sperm DNA Fragmentation, Genitourinary Infection by Mycoplasma in Male and the Pregnancy Outcomes After IUI in Their Partner Unknown status NCT01555047 Phase 4
47 Open-label, Follow-up Study of Oral Testosterone Undecanoate in Hypogonadal Men Unknown status NCT01699178 Phase 4 Oral testosterone undecanoate;Transdermal testosterone gel (AndroGel)
48 Treatment of Phimosis With Topical Steroid Cream -Double-blind, Randomized, Placebo-controlled Study Unknown status NCT01108198 Phase 4 Mometasone furoate cream;moisturizing cream
49 Efficacy and Safety of Naftopidil in Patient With Neurogenic Lower Urinary Tract Dysfunction Not Caused by Benign Prostatic Hyperplasia Unknown status NCT02034604 Phase 4 Naftofidil;Tamsulosin
50 Evaluation of Safety and Effectiveness of 2 Lower Dose Combined PDE5i's Versus Single Maximal Dose PDE5i Treatment Unknown status NCT01364701 Phase 4 Sildenafil 100 mg;Tadalafil 20 mg;Combination half of maximal dose for sildenafil & tadalafil

Search NIH Clinical Center for Reproductive System Disease

Genetic Tests for Reproductive System Disease

Genetic tests related to Reproductive System Disease:

id Genetic test Affiliating Genes
1 Abnormality of the Genital System 29

Anatomical Context for Reproductive System Disease

MalaCards organs/tissues related to Reproductive System Disease:

39
Prostate, Ovary, Bone, Testes, T Cells, Bone Marrow, Lymph Node

Publications for Reproductive System Disease

Variations for Reproductive System Disease

Expression for Reproductive System Disease

Search GEO for disease gene expression data for Reproductive System Disease.

Pathways for Reproductive System Disease

Pathways related to Reproductive System Disease according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.96 BMP15 CYP19A1 FSHR GDF9
2 10.76 AREG CYP19A1 FSHR
3 10.58 GNRH1 SHBG
4 10.53 CYP19A1 DAZL FSHR GDF9 ZP3
5 10.37 FSHR GNRH1

GO Terms for Reproductive System Disease

Cellular components related to Reproductive System Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.23 AMH AREG BMP15 GDF9 GNRH1 KLK3

Biological processes related to Reproductive System Disease according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 multicellular organism development GO:0007275 9.98 DAZ1 DAZ4 DAZL DPY19L2 GNRH1 PRM1
2 response to organic cyclic compound GO:0014070 9.72 AMH AREG GNRH1
3 BMP signaling pathway GO:0030509 9.67 AMH BMP15 GDF9
4 spermatid development GO:0007286 9.63 DPY19L2 FSHR PRM2
5 response to peptide hormone GO:0043434 9.58 AREG GNRH1 TRPV1
6 cell differentiation GO:0030154 9.56 AMH DAZ1 DAZ4 DAZL DPY19L2 PRM1
7 female gonad development GO:0008585 9.54 CYP19A1 FSHR
8 chromosome condensation GO:0030261 9.52 PRM1 PRM2
9 uterus development GO:0060065 9.51 CYP19A1 FSHR
10 regulation of MAPK cascade GO:0043408 9.5 BMP15 FSHR GDF9
11 gonad development GO:0008406 9.48 AMH FSHR
12 female gamete generation GO:0007292 9.43 BMP15 FSHR GDF9
13 DNA packaging GO:0006323 9.37 PRM1 PRM2
14 spermatogenesis GO:0007283 9.23 DAZ1 DAZ4 DAZL DPY19L2 FSHR PRM1
15 positive regulation of translational initiation GO:0045948 9.16 DAZ1 DAZL

Molecular functions related to Reproductive System Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.5 AMH GNRH1 PRL
2 growth factor activity GO:0008083 9.46 AMH AREG BMP15 GDF9
3 transforming growth factor beta receptor binding GO:0005160 9.13 AMH BMP15 GDF9
4 mRNA 3-UTR binding GO:0003730 8.96 DAZL
5 translation activator activity GO:0008494 8.62 DAZ1 DAZL

Sources for Reproductive System Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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