MCID: RSP006
MIFTS: 63

Respiratory System Disease

Categories: Respiratory diseases

Aliases & Classifications for Respiratory System Disease

MalaCards integrated aliases for Respiratory System Disease:

Name: Respiratory System Disease 12 14
Abnormality of the Respiratory System 28
Respiratory Tract Diseases 69
Respiration Disorders 69

Classifications:



External Ids:

Disease Ontology 12 DOID:1579
ICD10 32 J96-J99 J98 10
ICD9CM 34 510-519.99 519

Summaries for Respiratory System Disease

Disease Ontology : 12 A disease of anatomical entity that located in the respiratory system which extends from the nasal sinuses to the diaphragm.

MalaCards based summary : Respiratory System Disease, also known as abnormality of the respiratory system, is related to upper respiratory tract disease and helicobacter pylori infection, and has symptoms including rhinorrhea, inspiratory stridor and labored breathing. An important gene associated with Respiratory System Disease is TLR9 (Toll Like Receptor 9), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Methylprednisolone and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include the respiratory system which extends from the nasal sinuses to the diaphragm, lung and testes, and related phenotypes are hematopoietic system and homeostasis/metabolism

Related Diseases for Respiratory System Disease

Diseases related to Respiratory System Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 399)
# Related Disease Score Top Affiliating Genes
1 upper respiratory tract disease 31.2 CCL11 CD79A CXCL8 IL10 IL13 IL4
2 helicobacter pylori infection 30.3 CXCL8 IL10 IL1B TNF
3 nut allergy 10.8 IL13 IL5 TLR9
4 paragonimiasis 10.8 IL13 IL5 RNASE3
5 atopic keratoconjunctivitis 10.8 IL4 IL5 RNASE3
6 scleritis 10.8 IL4 IL5 TNF
7 intrinsic asthma 10.8 IL4 IL5 RNASE3
8 blepharoconjunctivitis 10.8 CCL11 IL4 RNASE3
9 intestinal schistosomiasis 10.8 IL13 IL4 IL5
10 tropical endomyocardial fibrosis 10.8 IL10 IL4 TNF
11 streptococcal toxic-shock syndrome 10.8 CXCL8 IL6 TNF
12 chronic tic disorder 10.8 IL13 IL4 IL5
13 giant papillary conjunctivitis 10.8 CCL11 CXCL8 IL4
14 chronic meningitis 10.8 CCL11 CRP IL5
15 status asthmaticus 10.8 CXCL8 IL5 RNASE3
16 recurrent corneal erosion 10.8 CXCL8 IL1B IL6
17 eye lymphoma 10.8 IL10 IL6 TLR9
18 endomyocardial fibrosis 10.8 IL10 IL4 TNF
19 cercarial dermatitis 10.8 IL1B IL4 IL5
20 cough variant asthma 10.8 IL4 IL5 RNASE3 TRPV1
21 necatoriasis 10.8 CXCL8 IL10 IL5
22 actinic prurigo 10.8 IL13 IL1B TNF
23 folliculitis 10.8 CCL11 IL4 IL5
24 opisthorchiasis 10.8 CXCL8 IL1B IL4
25 beta-lactam allergy 10.8 IL10 IL13 IL4
26 ascaris lumbricoides infection 10.8 IL1B IL5 IL6
27 haemophilus influenzae 10.8 CXCL8 IL1B TNF
28 cytokine deficiency 10.8 IL13 IL5
29 inflammatory bowel disease 4 10.8 IL13 IL4 IL5 RNASE3
30 sinusitis 10.8 CXCL8 IL5 RNASE3
31 viral pneumonia 10.8 CRP IL6 TLR9
32 punctate inner choroidopathy 10.8 IL10 TNF
33 scabies 10.8 CCL11 CXCL8 IL10
34 laryngitis 10.8 IL1B IL6 TNF
35 latex allergy 10.8 IL13 IL4 IL5 RNASE3
36 urinary schistosomiasis 10.8 IL13 IL4 IL5 RNASE3
37 meconium aspiration syndrome 10.8 CXCL8 IL6 TNF
38 acute transverse myelitis 10.8 CXCL8 IL10 IL6
39 vulvovaginitis 10.8 CCL11 CXCL8 IL10
40 crohn's colitis 10.8 CXCL8 IL1B TNF
41 angiostrongyliasis 10.8 CCL11 IL13 IL4 IL5
42 night blindness, congenital stationary, type 1a 10.8 ALB IL13 IL5
43 angioimmunoblastic lymphadenopathy with dysproteinemia 10.8 IL13 IL5 IL6 TNF
44 enterobiasis 10.8 IL13 IL4 IL5
45 esophageal disease 10.8 IL13 IL5 TRPV1
46 acute vascular insufficiency of intestine 10.8 IL1B IL6 TNF
47 poems syndrome 10.8 IL1B IL6 TNF
48 eosinophilic meningitis 10.8 CCL11 IL13 IL4 IL5
49 eosinophilic gastritis 10.8 CCL11 IL13 IL4 IL5
50 burns 10.8 ALB IL1B TNF

Comorbidity relations with Respiratory System Disease via Phenotypic Disease Network (PDN):


Acute Cystitis Bronchitis
Heart Disease Hypertension, Essential
Ischemic Heart Disease Respiratory Failure

Graphical network of the top 20 diseases related to Respiratory System Disease:



Diseases related to Respiratory System Disease

Symptoms & Phenotypes for Respiratory System Disease

UMLS symptoms related to Respiratory System Disease:


rhinorrhea, inspiratory stridor, labored breathing, larynx pain, neck tightness, respiratory distress, sore throat, nasal irritation, wheezing, pathological conditions, signs and symptoms, nasal congestion (finding), hemoptysis, edema, dyspnea, pleuritic pain, anoxemia, choking sensation, symptoms involving respiratory system and other chest symptoms, gasping for breath, neonatal cyanosis, bronchorrhea, expiratory wheeze, inspiratory wheeze, signs and symptoms of ill-defined conditions, other symptoms involving respiratory system and chest, sinus congestion, stridor, hoarseness, cyanosis, coughing, cheyne-stokes respiration, apnea

MGI Mouse Phenotypes related to Respiratory System Disease:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.18 AREG CCL11 CD79A IL10 IL13 IL1B
2 homeostasis/metabolism MP:0005376 10.17 ALB AREG CD79A CRP IL10 TLR9
3 immune system MP:0005387 10.13 TLR9 TNF TRPV1 AREG CCL11 CD79A
4 digestive/alimentary MP:0005381 10.06 ALB AREG IL10 IL13 IL4 IL5
5 liver/biliary system MP:0005370 9.76 ALB CD79A IL10 IL4 IL5 IL6
6 neoplasm MP:0002006 9.56 IL5 IL6 TNF TRPV1 ALB CD79A
7 respiratory system MP:0005388 9.23 CCL11 IL10 IL13 IL4 IL5 IL6

Drugs & Therapeutics for Respiratory System Disease

Drugs for Respiratory System Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1214)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 83-43-2 6741
2
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-24-8 5755
3
Oseltamivir Approved Phase 4,Phase 3,Phase 2,Phase 1 196618-13-0, 204255-11-8 65028
4
Caspofungin Approved Phase 4,Phase 3 162808-62-0, 179463-17-3 2826718 468682
5
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 22916-47-8 4189
6
Ropivacaine Approved Phase 4 84057-95-4 175805 71273
7
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
8
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 51-43-4 5816
9 Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1 329-65-7
10
Azithromycin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 83905-01-5 53477736 447043 55185
11
Cefuroxime Approved Phase 4,Phase 3,Phase 2 55268-75-2 5479529 5361202
12
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 85721-33-1 2764
13
Clarithromycin Approved Phase 4,Phase 3,Phase 2,Early Phase 1 81103-11-9 84029
14
Moxifloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 151096-09-2, 354812-41-2 152946
15
Penicillin G Approved, Vet_approved Phase 4,Phase 3,Phase 1 61-33-6 5904
16
Piperacillin Approved Phase 4,Phase 2,Phase 3 66258-76-2 43672
17
Salmon Calcitonin Approved, Investigational Phase 4,Phase 3,Phase 2 47931-85-1 16129616
18
Tazobactam Approved Phase 4,Phase 2,Phase 3,Phase 1 89786-04-9 123630
19
Adenosine Approved, Investigational Phase 4,Phase 2,Phase 1 58-61-7 60961
20
Budesonide Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 51333-22-3 5281004 63006
21
Bambuterol Approved, Investigational Phase 4,Phase 1 81732-65-2, 81732-46-9 54766
22
Terbutaline Approved Phase 4,Phase 3,Phase 1 23031-25-6 5403
23
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 299-42-3 9294
24
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 93-14-1 3516
25
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 90-82-4 7028
26
Montelukast Approved Phase 4,Phase 3,Phase 2,Phase 1 158966-92-8 5281040
27
Ipratropium Approved Phase 4,Phase 3,Phase 2,Phase 1 22254-24-6, 60205-81-4 43232
28
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
29
Metoprolol Approved, Investigational Phase 4,Phase 3 51384-51-1, 37350-58-6 4171
30
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 10102-43-9 145068
31
Sulbactam Approved Phase 4,Phase 3,Phase 2,Phase 1 68373-14-8
32
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 564-25-0 54671203
33
Tobramycin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 32986-56-4 36294 5496
34
Simvastatin Approved Phase 4,Phase 3,Phase 1,Phase 2 79902-63-9 54454
35
Cefotaxime Approved Phase 4 63527-52-6 5742673 456256
36
Cefoxitin Approved Phase 4 35607-66-0 441199
37
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 100986-85-4 149096
38
Ofloxacin Approved Phase 4,Phase 3,Phase 2,Phase 1 82419-36-1 4583
39
Linezolid Approved, Investigational Phase 4,Phase 3,Phase 2 165800-03-3 441401
40
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1 64-17-5 702
41
Amikacin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 37517-28-5 37768
42
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-28-2 5757
43
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2,Phase 1 57-63-6 5991
44
Metronidazole Approved Phase 4,Phase 3 443-48-1 4173
45
Norgestimate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 35189-28-7 6540478
46
Iloprost Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 78919-13-8 6443959
47
Mannitol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 69-65-8 6251 453
48
Isoniazid Approved, Investigational Phase 4,Phase 3 54-85-3 3767
49
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 76631-46-4, 113775-47-6 5311068 56032 68602
50
Omalizumab Approved, Investigational Phase 4,Phase 2 242138-07-4

Interventional clinical trials:

(show top 50) (show all 10000)

# Name Status NCT ID Phase Drugs
1 Exacerbation Prevention GOLD IV COPD With Non Invasive Mechanical Ventilation Unknown status NCT01481727 Phase 4
2 Extra-fine Formoterol/Beclomethasone in Asthmatic Crisis Unknown status NCT02345993 Phase 4 Extra fine Formoterol/Beclomethasone
3 Evaluation and Reconditioning of Marginal Lung Donors to Transplantation by ex Vivo Lung Perfusion Unknown status NCT01353105 Phase 4
4 Banlangen Granules Anti-seasonal Influenza Study Unknown status NCT02232945 Phase 4 placebo of oseltamivir phosphate;oseltamivir phosphate;Banlangen (Radix Isatidis) granules;placebo of Banlangen(Radix Isatidis) granules
5 Effect of Vitamin D as Adjunctive Therapy in Patients With Pulmonary Evolution Tuberculosis Unknown status NCT02464683 Phase 4
6 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease Unknown status NCT01595750 Phase 4 Roflumilast 500;Placebo
7 Efficacy and Safety of Caspofungin for Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease Unknown status NCT01499433 Phase 4 caspofungin
8 Cpap at Delivery Room for Preterm Infants Unknown status NCT01024361 Phase 4
9 Determining the Minimal Effective Volume (MEAV95) for Interscalene Brachial Plexus Block for Surgical Anesthesia Unknown status NCT01703130 Phase 4
10 Normal Oxygenation Versus Hyperoxia in the Intensive Care Unit (ICU) Unknown status NCT01319643 Phase 4 Oxygen
11 Bronchiolitis All-study, SE-Norway Unknown status NCT00817466 Phase 4 Racemic adrenaline;Isotonic saline
12 Procalcitonin as a Marker of Antibiotic Therapy in Patients With Lower Respiratory Tract Infections Unknown status NCT02171338 Phase 4
13 Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype Unknown status NCT01431625 Phase 4
14 Assessment of Airway Responsiveness and Treatment Efficacy in Asthmatics Unknown status NCT02574975 Phase 4 methacholine;adenosine monophosphate;leukotriene D4;budesonide /formoterol
15 The Effect of Bronchodilator on Eosinophilic Bronchitis and Cough Variant Asthma Unknown status NCT02002754 Phase 4 Bambuterol Hydrochloride tablets
16 Therapeutic Effect of Different Treatment Course With Inhaled Corticosteroids in Eosinophilic Bronchitis Patients Unknown status NCT02002715 Phase 4 Inhaled budesonide
17 Effects of Nutritional Supplementation in Malnourished Patients in Stable COPD Unknown status NCT02197871 Phase 4
18 Effects of Su-Huang Antitussive Capsule on Cough Variant Asthma Unknown status NCT01584804 Phase 4 Su-Huang antitussive capsule;Sugar pill
19 Effects of Leukotriene Modulator Montelukast on Cough Variant Asthma Unknown status NCT01404013 Phase 4 ICS/LABA;Montelukast;ICS/LABA and Montelukast
20 Efficacy and Safety of add-on Montelukast to Inhaled Budesonide in the Treatment of Nonasthmatic Eosinophilic Bronchitis Unknown status NCT01121016 Phase 4 Montelukast
21 The Efficacy and Safety of Salmeterol/Fluticasone Propionate vs Atropium/Albuterol in Patients COPD Unknown status NCT01243788 Phase 4 Salmeterol/Fluticasone Propionate
22 Seasonal Influenza Vaccine, Quadrivalent Versus Trivalent in Patients With Advanced Chronic Obstructive Pulmonary Disease Unknown status NCT02563184 Phase 4
23 Pulmonary Gas Exchange Response to Indacaterol in COPD Unknown status NCT02547558 Phase 4 Indacaterol
24 A Post-marketing Research on Jinyebaidu Granule in Treating Patients With Acute Upper Respiratory Infection Unknown status NCT02539277 Phase 4 Jinyebaidu granule;Fufangshuanghua granule;Jinyebaidu granule placebo;Fufangshuanghua granule placebo
25 Ambulatory Oxygen in Fibrotic Lung Disease (FLD) (AmbOx) Unknown status NCT02286063 Phase 4 Ambulatory Oxygen
26 An Efficacy Study of BCS Clearing the Oral Colonized Bacterium in Hospitalized Patients With COPD Unknown status NCT02269800 Phase 4 Benzalkonium chloride solution;Normal saline
27 Strategy to Improve Adherence of Roflumilast Unknown status NCT02018432 Phase 4 Roflumilast escalation dosage;Roflumilast conventional dosage
28 Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT01721291 Phase 4 SALBUTAMOL
29 Efficacy and Safety of Tulobuterol Patch Combined With Tiotropium Bromide for Relieving Dyspnea Symptom of Chronic Obstructive Pulmonary Disease Unknown status NCT01465906 Phase 4 tulobuterol;Tiotropium Bromide;tiotropium bromide
30 Comparing Treatment Efficacy With HD/MD Flu Plus Sal in Chronic Obstructive Pulmonary Disease (COPD) Patients Unknown status NCT01131806 Phase 4 fluticasone/ salmeterol 125/25 mcg/puff;fluticasone/ salmeterol 250/25 mcg/puff
31 The Role of Opinion Leaders in Enhancing Evidence-based Care After Chronic Obstructive Pulmonary Disease (COPD) Emergency Department (ED) Visits Unknown status NCT01107613 Phase 4
32 Metoprolol and Formoterol in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT00288548 Phase 4 Metoprolol
33 Can Advair and Flovent Reduce Systemic Inflammation Related to Chronic Obstructive Pulmonary Disease (COPD)? A Multi-Center Randomized Controlled Trial Unknown status NCT00120978 Phase 4 Advair;Flovent
34 Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure Unknown status NCT01873521 Phase 4
35 Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy Patients Unknown status NCT01382368 Phase 4 Sildenafil
36 Exhaled NO Based Treatment of Chronic Obstructive Pulmonary Disease (COPD), ICS/LABA Versus LAMA Unknown status NCT02546349 Phase 4 fluticasone/salmeterol, tiotropium
37 Vitamin D as an Adjunctive Treatment in Patients With Non-Cystic Fibrosis Bronchiectasis Unknown status NCT02507843 Phase 4 Cholecalciferol;Placebo
38 FRC Guided Therapy in Acute Respiratory Failure Unknown status NCT01280019 Phase 4
39 Piperacillin Sodium and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01897831 Phase 4 xin te mie
40 Doxycycline and Airway Inflammation in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT00857038 Phase 4 Doxycycline;Placebo
41 Piperacillin Sodium and Sulbactam Sodium for Injection(2:1) for Treatment of Respiratory and Urinary System Infection Unknown status NCT01760109 Phase 4 Piperacillin Sodium and Sulbactam Sodium
42 EUROPT Clinical Trial to Study the Efficacy of One-Way Valve Implantation (New Treatment Algorithm) in Patients With Heterogeneous Emphysema Unknown status NCT00730301 Phase 4
43 A Study to Access Safety and Efficacy of Nebulized Tobramycin in Patients With Bronchiectasis Unknown status NCT01677403 Phase 4 Tobramycin;Saline
44 Simvastatin in Chronic Obstructive Pulmonary Disease (COPD) Unknown status NCT00680641 Phase 4 Simvastatin;Placebo
45 Improving Primary Spontaneous Pneumothorax (PSP) Treatment Techniques in VATS Unknown status NCT01463553 Phase 4
46 Study on Cefotaxime and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01426191 Phase 4 xinzhijun
47 Inflammatory Response to Anti Inflammatory Therapy in Children With Sleep Disordered Breathing Unknown status NCT00299910 Phase 4 Montelukast
48 Clinical Pathway Based on Procalcitonin Levels for the Management of Community-acquired Pneumonia in Outpatients Unknown status NCT02600806 Phase 4 Azithromycin;Levofloxacin
49 Corticosteroid Therapy for Severe Community-Acquired Pneumonia Unknown status NCT02552342 Phase 4 methylprednisolone;Normal saline
50 Pharmacokinetic and Pharmacodynamic Evaluation of Linezolid Administered Intravenously in MRSA-positive, Morbidly Obese Patients With Pneumonia Unknown status NCT01805284 Phase 4 Linezolid

Search NIH Clinical Center for Respiratory System Disease

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Genetic Tests for Respiratory System Disease

Genetic tests related to Respiratory System Disease:

# Genetic test Affiliating Genes
1 Abnormality of the Respiratory System 28

Anatomical Context for Respiratory System Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Respiratory System Disease:

18
The Respiratory System Which Extends From The Nasal Sinuses To The Diaphragm

MalaCards organs/tissues related to Respiratory System Disease:

38
Lung, Testes, Heart, Endothelial, Liver, Brain, Bone

Publications for Respiratory System Disease

Articles related to Respiratory System Disease:

# Title Authors Year
1
Respiratory System Disease. ( 27469180 )
2016
2
Helicobacter pylori infection as a possible risk factor for respiratory system disease: a review of the literature. ( 16759841 )
2007
3
Alpha 1-antitrypsin gene polymorphism related to respiratory system disease. ( 2887693 )
1987
4
Death from respiratory system disease among Seventh-Day Adventist men. ( 5953042 )
1966

Variations for Respiratory System Disease

Expression for Respiratory System Disease

Search GEO for disease gene expression data for Respiratory System Disease.

Pathways for Respiratory System Disease

Pathways related to Respiratory System Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.08 CCL11 CD79A CRP CXCL8 IL10 IL13
2
Show member pathways
13.88 AREG CCL11 CXCL8 IL10 IL13 IL1B
3
Show member pathways
13.71 CCL11 CXCL8 IL10 IL13 IL1B IL4
4
Show member pathways
13.64 AREG CCL11 CXCL8 IL10 IL13 IL1B
5
Show member pathways
13.48 AREG CCL11 CXCL8 IL10 IL13 IL1B
6
Show member pathways
13.46 CCL11 CXCL8 IL10 IL13 IL1B IL4
7
Show member pathways
13.4 AREG CCL11 CXCL8 IL10 IL13 IL1B
8
Show member pathways
13.02 CXCL8 IL1B IL6 MUC5B TLR9 TNF
9
Show member pathways
12.91 CXCL8 IL13 IL1B IL4 IL6 TLR9
10
Show member pathways
12.91 CCL11 CXCL8 IL10 IL13 IL1B IL4
11
Show member pathways
12.75 AREG IL1B IL6 TLR9 TNF
12
Show member pathways
12.71 IL10 IL13 IL1B IL4 IL5 IL6
13
Show member pathways
12.7 CD79A IL13 IL4 IL5 MS4A2 TNF
14
Show member pathways
12.68 CD79A IL10 IL4 MS4A2 TNF
15 12.67 CD79A IL10 IL1B IL4 TLR9 TNF
16
Show member pathways
12.64 CXCL8 IL10 IL1B IL6 TLR9 TNF
17
Show member pathways
12.55 IL10 IL1B IL4 IL5 IL6 TNF
18
Show member pathways
12.47 IL10 IL13 IL4 IL5 IL6
19
Show member pathways
12.46 ALB CRP IL1B IL4 IL6 TNF
20
Show member pathways
12.39 CCL11 CXCL8 IL13 IL1B IL4 IL5
21 12.34 IL10 IL1B IL6 TLR9 TNF
22
Show member pathways
12.32 CXCL8 IL1B IL6 TNF
23
Show member pathways
12.32 CCL11 CXCL8 IL1B IL4 IL6 TLR9
24
Show member pathways
12.31 CXCL8 IL6 TLR9 TNF
25
Show member pathways
12.3 IL10 IL1B IL4 TNF
26 12.29 CXCL8 IL10 IL13 IL1B IL6 TNF
27
Show member pathways
12.27 CXCL8 IL10 IL13 IL1B IL4 IL5
28 12.14 CXCL8 IL1B IL4 IL6 TNF
29 12.12 CD79A IL10 IL4 IL5 IL6 TNF
30
Show member pathways
12.11 IL13 IL1B IL5 TLR9
31
Show member pathways
12.07 IL10 IL1B IL6 TLR9 TNF
32 12.03 IL1B IL4 IL5 IL6 TNF
33 12.03 CCL11 CXCL8 IL10 IL13 IL1B IL4
34 12.02 CXCL8 IL10 IL1B IL6 TNF
35 12 CXCL8 IL1B IL6 TNF
36
Show member pathways
11.97 IL1B IL4 IL6 TLR9
37 11.96 CXCL8 IL1B IL6 TNF
38 11.94 CXCL8 IL13 IL4 IL5 IL6
39 11.93 IL10 IL13 IL1B IL4 IL5 TNF
40 11.9 CXCL8 IL10 IL1B IL6 TNF
41
Show member pathways
11.88 CXCL8 IL4 IL5 TNF
42 11.88 IL10 IL1B IL6 TLR9 TNF
43 11.83 IL10 IL4 IL5 IL6 TLR9 TNF
44 11.79 CCL11 IL10 IL4 IL5
45
Show member pathways
11.78 CXCL8 IL1B IL6 TNF
46 11.71 CXCL8 IL1B IL6 TNF
47 11.68 CXCL8 IL10 IL1B IL6 TLR9 TNF
48 11.63 AREG CCL11 IL10 IL13 IL4 IL5
49 11.58 IL1B IL5 IL6
50 11.54 IL1B IL6 TNF

GO Terms for Respiratory System Disease

Cellular components related to Respiratory System Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.83 ALB CCL11 CRP CXCL8 IL10 IL13
2 external side of plasma membrane GO:0009897 9.55 CD79A IL13 MS4A2 TNF TRPV1
3 extracellular space GO:0005615 9.53 ALB AREG CCL11 CRP CXCL8 IL10

Biological processes related to Respiratory System Disease according to GeneCards Suite gene sharing:

(show all 45)
# Name GO ID