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MCID: RST001
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Restless Legs Syndrome malady |
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Sources: 30MedlinePlus, 40NINDS, 59Wikipedia, 29MalaCards See all sources Fully expand this MalaCard Export this MalaCard |
MedlinePlus:30 Restless legs syndrome (rls) causes a powerful urge to move your legs. your legs become uncomfortable when you are lying down or sitting. some people describe it as a creeping, crawling, tingling, or burning sensation. moving makes your legs feel better, but not for long. rls can make it hard to fall asleep and stay asleep.
in most cases, there is no known cause for rls. in other cases, rls is caused by a disease or condition, such as anemia or pregnancy. some medicines can also cause temporary rls. caffeine, tobacco, and alcohol may make symptoms worse.
lifestyle changes, such as regular sleep habits, relaxation techniques, and moderate exercise during the day can help. if those don't work, medicines may reduce the symptoms of rls.
most people with rls also have a condition called periodic limb movement disorder (plmd). plmd is a condition in which a person's legs twitch or jerk uncontrollably, usually during sleep. plmd and rls can also affect the arms.
nih: national heart, lung, and blood institute
MalaCards: Restless Legs Syndrome, also known as restless legs, is related to parkinson's disease and sleep disorder. An important gene associated with Restless Legs Syndrome is BTBD9 (BTB (POZ) domain containing 9), and among its related pathways are iron metabolism in placenta and Dopamine receptors. The drugs carbamazepine and clonazepam and the compounds talipexole and sch 23390 have been mentioned in the context of this disorder. Affiliated tissues include brain, brain and lung, and related mouse phenotype nervous system. NINDS:40 Restless legs syndrome (RLS) is a neurological disorder characterized by unpleasant sensations in the legs and an uncontrollable, and sometimes overwhelming, urge to move them for relief. Individuals affected with the disorder often describe the sensations as throbbing, polling, or creeping. The sensations range in severity from uncomfortable to irritating to painful. Wikipedia:59 Restless Legs Syndrome (RLS), also known as Willis-Ekbom disease (WED), is a neurological disorder... more... |
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Sources: 8Disease Ontology, 40NINDS, 41Novoseek, 56UMLS, 30MedlinePlus, 31MeSH See all sources |
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Sources: 5CenterWatch, 38NIH Clinical Center, 6ClinicalTrials, 56UMLS, 37NDF-RT See all sources |
Approved drugs:Search CenterWatch for restless legs syndrome Drug clinical trials:Search ClinicalTrials for restless legs syndrome Search NIH Clinical Center for restless legs syndrome Search CenterWatch for restless legs syndrome Inferred drug relations via UMLS56/NDF-RT37: |
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Sources: 29MalaCards See all sources |
MalaCards organs/tissues related to restless legs syndrome:29Brain, Lung, Heart
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Sources: 33MGI, 26inGenious Targeting Laboratory See all sources |
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Sources: 47PubMed See all sources |
Articles related to restless legs syndrome:(show all 46)
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Sources: 16GeneCards, 42Novus Biologicals, 26inGenious Targeting Laboratory See all sources |
Genes related to restless legs syndrome:(show all 20)
Products for genes related to restless legs syndrome disease:
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Sources: 1BioGPS See all sources |
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Sources: 34NCBI BioSystems Database, 50Reactome, 46PharmGKB, 48QIAGEN See all sources |
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Sources: 41Novoseek, 55Tocris Bioscience, 11DrugBank, 46PharmGKB, 22HMDB, 2BitterDB See all sources |
Compounds related to restless legs syndrome according to GeneCards/GeneDecks:(show top 50) (show all 102)
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Sources: 15Gene Ontology See all sources |
Cellular components related to restless legs syndrome according to GeneCards/GeneDecks:
Biological processes related to restless legs syndrome according to GeneCards/GeneDecks:(show all 25)
Molecular functions related to restless legs syndrome according to GeneCards/GeneDecks:
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