Aliases & Classifications for Reticuloendotheliosis

MalaCards integrated aliases for Reticuloendotheliosis:

Name: Reticuloendotheliosis 50 52
Reticuloendotheliosis, X-Linked 50 69

Characteristics:

HPO:

32
reticuloendotheliosis:
Inheritance x-linked inheritance
Onset and clinical course infantile onset


Classifications:



Summaries for Reticuloendotheliosis

MalaCards based summary : Reticuloendotheliosis, also known as reticuloendotheliosis, x-linked, is related to intrapelvic lymph node leukemic reticuloendotheliosis and histoplasmosis, and has symptoms including jaundice, hepatosplenomegaly and anemia. An important gene associated with Reticuloendotheliosis is REL (REL Proto-Oncogene, NF-KB Subunit), and among its related pathways/superpathways are Toll-Like receptor Signaling Pathways and TNFR1 Pathway. Affiliated tissues include lung and spleen, and related phenotypes are liver/biliary system and respiratory system

Wikipedia : 72 Histoplasmosis (also known as \"Cave disease,\" \"Darling\'s disease,\" \"Ohio valley disease,\"... more...

Related Diseases for Reticuloendotheliosis

Diseases related to Reticuloendotheliosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
id Related Disease Score Top Affiliating Genes
1 intrapelvic lymph node leukemic reticuloendotheliosis 11.9
2 histoplasmosis 11.4
3 omenn syndrome 11.0
4 hairy cell leukemia 10.9
5 classic hairy cell leukemia 10.8
6 letterer-siwe disease 10.3
7 eosinophilic granuloma 9.9
8 laryngotracheitis 9.8
9 lymphosarcoma 9.8
10 follicular mucinosis 9.8
11 retinis pigmentosa deafness hypogenitalism 7.9 JARID2 LOC100422456 REL RELA RELB

Graphical network of the top 20 diseases related to Reticuloendotheliosis:



Diseases related to Reticuloendotheliosis

Symptoms & Phenotypes for Reticuloendotheliosis

Human phenotypes related to Reticuloendotheliosis:

32
id Description HPO Frequency HPO Source Accession
1 jaundice 32 HP:0000952
2 hepatosplenomegaly 32 HP:0001433
3 anemia 32 HP:0001903
4 lymphadenopathy 32 HP:0002716

MGI Mouse Phenotypes related to Reticuloendotheliosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 9.26 JARID2 REL RELA RELB
2 respiratory system MP:0005388 8.92 JARID2 REL RELA RELB

Drugs & Therapeutics for Reticuloendotheliosis

Search Clinical Trials , NIH Clinical Center for Reticuloendotheliosis

Genetic Tests for Reticuloendotheliosis

Anatomical Context for Reticuloendotheliosis

MalaCards organs/tissues related to Reticuloendotheliosis:

39
Lung, Spleen

Publications for Reticuloendotheliosis

Articles related to Reticuloendotheliosis:

(show all 36)
id Title Authors Year
1
Wild Birds, a Source of Reticuloendotheliosis Virus Infection for the Endangered Attwater's Prairie-Chicken ( Tympanuchus cupido attwateri)? ( 28192047 )
2017
2
Analysis of microRNA expression profile in specific pathogen-free chickens in response to reticuloendotheliosis virus infection. ( 28032193 )
2017
3
Characterization of a Gallid herpesvirus 2 strain with novel reticuloendotheliosis virus long terminal repeat inserts. ( 28194622 )
2017
4
Co-Infection with Marek's Disease Virus and Reticuloendotheliosis Virus Increases Illness Severity and Reduces Marek's Disease Vaccine Efficacy. ( 28635675 )
2017
5
Activation of gga-miR-155 by reticuloendotheliosis virus T strain and its contribution to transformation. ( 28113043 )
2017
6
Immunoprotection induced by CpG-ODN/Poly(I:C) combined with recombinant gp90 protein in chickens against reticuloendotheliosis virus infection. ( 28465147 )
2017
7
Analysis of the spleen proteome of chickens infected with reticuloendotheliosis virus. ( 28097424 )
2017
8
Bouroncle BA, Wiseman BK, Doan CA. Leukemic reticuloendotheliosis. Blood. 1958;13(7):609-630. ( 27013208 )
2016
9
Genome analysis and pathogenicity of reticuloendotheliosis virus isolated from a contaminated vaccine seed against infectious bursal disease virus: first report in China. ( 27609617 )
2016
10
Protective efficacy of a recombinant bacterial artificial chromosome clone of a very virulent Marek's disease virus containing a reticuloendotheliosis virus long terminal repeat. ( 27258614 )
2016
11
Emergence of reticuloendotheliosis virus in pigeons in Guangdong Province, Southern China. ( 27120185 )
2016
12
A recombinant field strain of Marek's disease (MD) virus with reticuloendotheliosis virus long terminal repeat insert lacking the meq gene as a vaccine against MD. ( 25562789 )
2015
13
Isolation and full-genome sequence of two reticuloendotheliosis virus strains from mixed infections with Marek's disease virus in China. ( 25850423 )
2015
14
Synergistic pathogenic effects of co-infection of subgroup J avian leukosis virus and reticuloendotheliosis virus in broiler chickens. ( 25484188 )
2015
15
Soluble expression and enzymatic activity evaluation of protease from reticuloendotheliosis virus. ( 26102339 )
2015
16
Common occurrence of Gallid herpesvirus-2 with reticuloendotheliosis virus in chickens caused by possible contamination of vaccine stocks. ( 25641090 )
2015
17
Transcriptional Profiling of Host Gene Expression in Chicken Embryo Fibroblasts Infected with Reticuloendotheliosis Virus Strain HA1101. ( 25973612 )
2015
18
Construction and characterization of a recombinant reticuloendotheliosis virus expressing enhanced green fluorescent protein. ( 26112763 )
2015
19
Isolation, identification, and whole genome sequencing of reticuloendotheliosis virus from a vaccine against Marek's disease. ( 25725074 )
2015
20
Synergetic effects of subgroup J avian leukosis virus and reticuloendotheliosis virus co-infection on growth retardation and immunosuppression in SPF chickens. ( 25042879 )
2014
21
Reticuloendotheliosis virus strain T induces miR-155, which targets JARID2 and promotes cell survival. ( 19759154 )
2009
22
Orbital lymphosarcoma associated with reticuloendotheliosis virus in a peafowl. ( 9702227 )
1998
23
Effects of reticuloendotheliosis virus on the response of chickens to infectious laryngotracheitis virus. ( 18770210 )
1982
24
Familial reticuloendotheliosis with eosinophilia and follicular mucinosis. ( 4337378 )
1972
25
Apparent cure of Letterer-Siwe disease. Seventeen-year survival of identical twins with nonlipoid reticuloendotheliosis. ( 5952210 )
1966
26
Congenital Letterer-Siwe disease (reticuloendotheliosis) in a term stillborn infant. ( 13681769 )
1960
27
The course and prognosis of reticuloendotheliosis (eosinophilic granuloma, SchA1ller-Christian disease and Letterer-Siwe disease); a study of forty cases. ( 13410955 )
1957
28
Systemic reticuloendotheliosis (Letterer-Siwe disease) in the adult male. ( 13181289 )
1954
29
Recovery from acute infantile non-lipoid reticuloendotheliosis (Letterer-Siwe disease). ( 13228048 )
1954
30
Malignant reticuloendotheliosis (Letterer-Siwe disease); report of case with normocholesteremic lipid granulomatosis and eosinophilic granuloma. ( 13137595 )
1954
31
Acute reticuloendotheliosis (Letterer-Siwe disease); report of a case in which several unusual features are combined. ( 14902100 )
1952
32
The ameliorative effect of antibiotics on nonlipoid reticuloendotheliosis (Letterer-Siwe disease) in identical twins. ( 14908834 )
1952
33
Familial incidence of non-lipoid reticuloendotheliosis (Letterer-Siwe disease). ( 14904103 )
1951
34
Nonlipid reticuloendotheliosis; Letterer-Siwe disease; report of a case. ( 18149231 )
1949
35
Systemic aleukemic reticuloendotheliosis; Letterer-Siwe disease. ( 18882062 )
1948
36
Reticuloendotheliosis (Letterer-Siwe disease). ( 20251575 )
1947

Variations for Reticuloendotheliosis

Expression for Reticuloendotheliosis

Search GEO for disease gene expression data for Reticuloendotheliosis.

Pathways for Reticuloendotheliosis

Pathways related to Reticuloendotheliosis according to GeneCards Suite gene sharing:

(show all 41)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.69 REL RELA RELB
2
Show member pathways
12.63 REL RELA RELB
3
Show member pathways
12.49 REL RELA RELB
4
Show member pathways
12.46 REL RELA RELB
5
Show member pathways
12.4 REL RELA RELB
6
Show member pathways
12.36 REL RELA RELB
7
Show member pathways
12.36 REL RELA RELB
8 12.32 REL RELA RELB
9
Show member pathways
12.32 REL RELA RELB
10
Show member pathways
12.2 REL RELA RELB
11
Show member pathways
12.19 REL RELA RELB
12
Show member pathways
12.13 REL RELA RELB
13
Show member pathways
12.12 REL RELA RELB
14
Show member pathways
12.01 REL RELA RELB
15
Show member pathways
12 REL RELA RELB
16
Show member pathways
11.98 REL RELA RELB
17
Show member pathways
11.92 REL RELA RELB
18 11.87 REL RELA RELB
19
Show member pathways
11.83 REL RELA RELB
20 11.79 RELA RELB
21
Show member pathways
11.77 REL RELA RELB
22
Show member pathways
11.77 REL RELA RELB
23 11.7 REL RELA RELB
24 11.66 RELA RELB
25
Show member pathways
11.65 REL RELA RELB
26
Show member pathways
11.59 RELA RELB
27
Show member pathways
11.53 REL RELA RELB
28 11.51 REL RELA RELB
29
Show member pathways
11.43 REL RELA RELB
30
Show member pathways
11.41 REL RELA RELB
31 11.38 REL RELA RELB
32
Show member pathways
11.36 REL RELA
33
Show member pathways
11.31 REL RELA RELB
34 11.28 REL RELA RELB
35 11.14 REL RELA RELB
36 11.08 REL RELA RELB
37 10.97 RELA RELB
38 10.94 REL RELA RELB
39 10.74 REL RELA
40 10.65 REL RELA RELB
41 10.55 JARID2 REL RELA RELB

GO Terms for Reticuloendotheliosis

Cellular components related to Reticuloendotheliosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 I-kappaB/NF-kappaB complex GO:0033256 8.8 REL RELA RELB

Biological processes related to Reticuloendotheliosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of transcription, DNA-templated GO:0045892 9.58 JARID2 RELA RELB
2 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.46 RELA RELB
3 negative regulation of transcription from RNA polymerase II promoter GO:0000122 9.46 JARID2 REL RELA RELB
4 liver development GO:0001889 9.43 JARID2 RELA
5 inflammatory response GO:0006954 9.43 REL RELA RELB
6 NIK/NF-kappaB signaling GO:0038061 9.37 REL RELB
7 I-kappaB kinase/NF-kappaB signaling GO:0007249 9.32 REL RELB
8 negative regulation of interferon-beta production GO:0032688 8.96 REL RELB
9 response to cytokine GO:0034097 8.8 REL RELA RELB

Molecular functions related to Reticuloendotheliosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 DNA binding GO:0003677 9.62 JARID2 REL RELA RELB
2 RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 9.26 REL RELA
3 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding GO:0001205 9.16 REL RELA
4 RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 9.13 JARID2 RELA RELB
5 chromatin binding GO:0003682 8.92 JARID2 REL RELA RELB

Sources for Reticuloendotheliosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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