MCID: RTN017
MIFTS: 53

Retinal Detachment malady

Eye category

Summaries for Retinal Detachment

Sources:
34MedlinePlus, 64Wikipedia, 47OMIM, 33MalaCards
See all sources

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MedlinePlus:34 The retina is a layer of tissue in the back of your eye that senses light and sends images to your brain. it provides the sharp, central vision needed for reading, driving, and seeing fine detail. a retinal detachment lifts or pulls the retina from its normal position. it can occur at any age, but it is more common in people over age 40. it affects men more than women and whites more than african americans. a retinal detachment is also more likely to occur in people who are extremely nearsighted have had a retinal detachment in the other eye have a family history of retinal detachment have had cataract surgery have other eye diseases or disorders have had an eye injury symptoms include an increase in the number of floaters, which are little "cobwebs" or specks that float about in your field of vision, and/or light flashes in the eye. it may also seem like there is a "curtain" over your field of vision. a retinal detachment is a medical emergency. if not promptly treated, it can cause permanent vision loss. if you have any symptoms, see an eye care professional immediately. treatment includes different types of surgery. nih: national eye institute

MalaCards: Retinal Detachment is related to proliferative vitreoretinopathy and macular holes. An important gene associated with Retinal Detachment is COL2A1 (collagen, type II, alpha 1), and among its related pathways are Endochondral Ossification and p70S6K Signaling. The compounds estrogen and matrigel have been mentioned in the context of this disorder. Related mouse phenotypes are respiratory system and pigmentation.

Wikipedia:64 Retinal detachment is a disorder of the eye in which the retina peels away from its underlying layer of... more...

Description from OMIM:47 312530

Aliases & Classifications for Retinal Detachment

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 34MedlinePlus, 61UMLS, 57SNOMED-CT, 35MeSH, 27ICD9CM, 40NCIt, 47OMIM, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye


Aliases & Descriptions:

retinal detachment 8 10 45 34 61


External Ids:

Disease Ontology8 DOID:5327
MeSH35 D012163
ICD9CM27 361.9
NCIt40 C26874
OMIM47 312530
ICD1025 H33.0

Related Diseases for Retinal Detachment

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Retinal Detachment via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 300)
idRelated DiseaseScoreTop Affiliating Genes
1proliferative vitreoretinopathy31.4TGFB2, GFAP, GLUL, TIMP1, TIMP2
2macular holes31.1HPRT1, SERPINF1, TGFB2
3proliferative diabetic retinopathy30.9TIMP2, TIMP1, VEGFA, GFAP, SERPINF1, TGFB2
4uveitis30.6TGFB2, SERPINF1
5neovascular glaucoma30.4VEGFA, TGFB2
6blindness30.3RS1, SERPINF1, VEGFA, COL2A1
7vasculitis30.2PRG2
8adenocarcinoma30.2TIMP2, TIMP1, PDGFA, PDGFB, VEGFA, SRF
9arthritis30.2COL2A1, TIMP2, TIMP1, HPRT1, MMP3, SRF
10tuberculosis30.0PDGFB, GLUL, SRF
11retinopathy of prematurity30.0VEGFA, FZD4
12squamous cell carcinoma30.0SRF, MMP3, HPRT1, VEGFA, PDGFB, PDGFA
13vitreous detachment10.8
14coloboma10.7
15cytomegalovirus retinitis10.6
16coats disease10.5
17central serous chorioretinopathy10.5
18cystoid macular edema10.5
19retinal melanoma10.5
20hellp syndrome10.4
21exudative vitreoretinopathy10.4
22choroiditis10.4
23stickler syndrome10.4
24n syndrome10.4
25thrombotic thrombocytopenic purpura10.4
26central retinal vein occlusion10.4
27sympathetic ophthalmia10.4
28eclampsia10.3
29strabismus10.3
30sturge-weber syndrome10.3
31weber syndrome10.3
32aniridia10.3
33vogt-koyanagi-harada disease10.3
34acute retinal necrosis syndrome10.3
35diabetic macular edema10.3
36retina lymphoma10.3
37multifocal choroiditis10.3
38vitreoretinal degeneration10.3
39neuroretinitis10.2
40posterior scleritis10.2
41retinal perforation10.2
42spondyloepiphyseal dysplasia congenita10.2
43retinal lattice degeneration10.2
44rubeosis iridis10.2
45equatorial staphyloma10.2
46acute leukemia10.2
47stickler syndrome type 110.2
48wagner syndrome10.2
49knobloch syndrome10.2
50knobloch syndrome type i10.2

Graphical network of the top 20 diseases related to Retinal Detachment:



Diseases related to retinal detachment

Clinical Features for Retinal Detachment

Sources:
47OMIM
See all sources

Clinical features from OMIM:

312530

Drugs & Therapeutics for Retinal Detachment

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Retinal Detachment

Drug clinical trials:

Search ClinicalTrials for Retinal Detachment

Search NIH Clinical Center for Retinal Detachment

Search CenterWatch for Retinal Detachment

Genetic Tests for Retinal Detachment

Anatomical Context for Retinal Detachment

Animal Models for Retinal Detachment or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Retinal Detachment:

37 (show all 18)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000538810.7COL2A1, PRG2, VEGFA, TGFB2
2MP:000118610.6RS1
3MP:000539110.5TGFB2, COL2A1, PDGFB, FZD4, GAP43, VEGFA
4MP:000537610.5PDGFA, PDGFB, FZD4, CBS, HPRT1, GFAP
5MP:000536910.5PDGFA, PDGFB, FZD4, CBS, HPRT1, GFAP
6MP:000538510.5COL2A1, TIMP1, PDGFA, PDGFB, FZD4, CBS
7MP:000536710.5COL2A1, PDGFA, PDGFB, FZD4, VEGFA, CBS
8MP:000363110.4GAP43, FZD4, PDGFB, PDGFA, TIMP2, COL2A1
9MP:000538010.4COL2A1, PDGFA, PDGFB, FZD4, VEGFA, CBS
10MP:000537810.4FZD4, PDGFB, PDGFA, TIMP1, COL2A1, GAP43
11MP:000538710.4COL2A1, TIMP2, TIMP1, PDGFB, GAP43, PRG2
12MP:000538910.4TIMP1, PDGFA, PDGFB, FZD4, VEGFA, CBS
13MP:000538110.4COL2A1, FZD4, VEGFA, HPRT1, GFAP, SERPINF1
14MP:001076810.4FZD4, PDGFB, PDGFA, TIMP1, COL2A1, GAP43
15MP:000537910.3CBS, HPRT1, SERPINF1
16MP:000538610.2COL2A1, TIMP2, FZD4, VEGFA, CBS, GLUL
17MP:000539710.2TIMP1, PDGFB, PRG2, VEGFA, CBS, HPRT1
18MP:000538210.0COL2A1, PDGFA, VEGFA, CBS, HPRT1, TGFB2

Publications for Retinal Detachment

Sources:
51PubMed
See all sources

Articles related to Retinal Detachment:

(show top 50)    (show all 942)
idTitleAuthorsYear
1
Efficacy of Short-term Postoperative Perfluoro-n-octane Tamponade for Pediatric Complex Retinal Detachment. (24332376)
2014
2
Characteristics of rhegmatogenous retinal detachment and their relationship to visual outcome. (23788207)
2013
3
Bullous hemorrhagic retinal detachment because of massive subretinal hemorrhage in patients with age-related macular degeneration. (23518899)
2013
4
25-gauge pars plana vitrectomy with medium-term postoperative perfluoro-n-octane tamponade for inferior retinal detachment. (23418732)
2013
5
Short-term external buckling with pneumatic retinopexy for retinal detachment with inferior retinal breaks. (23953155)
2013
6
The outcomes of pars plana vitrectomy without endotamponade for tractional retinal detachment secondary to proliferative diabetic retinopathy. (24195047)
2013
7
Functional and anatomical remodeling in human retinal detachment. (22406310)
2012
8
Intravitreal injection of soluble erythropoietin receptor exacerbates photoreceptor cell apoptosis in a rat model of retinal detachment. (22906152)
2012
9
Non-buckled vitrectomy for retinal detachment with inferior breaks and proliferative vitreoretinophathy. (23166870)
2012
10
Bilateral exudative retinal detachment due to retinal pigment epithelial tears successfully treated by vitrectomy and scleral window surgery. (21951865)
2012
11
A novel experimental mouse model of retinal detachment: complete functional and histologic recovery of the retina. (22323470)
2012
12
Localized foveal detachment in a patient with central retinal artery occlusion with cilioretinal sparing. (21786272)
2012
13
Heavy internal tamponade for cases with complicated retinal detachment. (21484628)
2011
14
Comparison of 20-, 23-, and 25-gauge pars plana vitrectomy in pseudophakic rhegmatogenous retinal detachment repair. (21210580)
2011
15
Tumor necrosis factor-alpha mediates photoreceptor death in a rodent model of retinal detachment. (21402953)
2011
16
Twenty-three-gauge pars plana vitrectomy, Densiron-68, and 360A^ endolaser versus combined 20-gauge pars plana vitrectomy, scleral buckle, and SF6 for pseudophakic retinal detachment with inferior retinal breaks. (21386767)
2011
17
Intraoperative spectral-domain optical coherence tomography during complex retinal detachment repair. (21830748)
2011
18
The effect of scleral exoplant removal on strabismus following retinal detachment repair. (21907112)
2011
19
Resolution of total retinal detachment in Coats' disease with intravitreal injection of bevacizumab. (21080196)
2011
20
Efficacy of primary silicone oil tamponade for the treatment of retinal detachment caused by macular hole in high myopia. (21130979)
2011
21
Retinal detachment in morning glory syndrome with large hole in the excavated disc. (21607925)
2011
22
The predisposing pathology and clinical characteristics in the Scottish retinal detachment study. (21561662)
2011
23
Retinal detachment after bevacizumab. (22047908)
2011
24
Retinal detachment as a presenting feature of metastatic esophageal adenocarcinoma. (20139887)
2010
25
Serous retinal detachment associated with retinal vein occlusion. (20103055)
2010
26
Exudative retinal detachment following photodynamic therapy for retinal capillary hemangioma. (20436538)
2010
27
Treatment of retinal pigment epithelial detachment with antiangiogenic therapy. (20463807)
2010
28
Elevated erythropoietin in vitreous of patients with rhegmatogenous retinal detachment and proliferative vitreoretinopathy. (19602911)
2009
29
Results of surgery on macular holes that develop after rhegmatogenous retinal detachment. (18227202)
2008
30
Retinal detachment with macular hole following intravitreal bevacizumab in patient with severe proliferative diabetic retinopathy. (18441183)
2008
31
En bloc perfluorodissection for tractional retinal detachment in proliferative diabetic retinopathy. (18423870)
2008
32
Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis. (17284607)
2007
33
Expression of matrix metalloproteinases in the subretinal fluid correlates with the extent of rhegmatogenous retinal detachment. (16941143)
2007
34
Serous macular detachment in central retinal vein occlusion. (16077350)
2005
35
Outcomes of surgery for retinal detachment associated with proliferative vitreoretinopathy using perfluoro-n-octane: a multicenter study. (12967798)
2003
36
Surgical management of retinal detachment with choroidal coloboma. (12220000)
2002
37
Bilateral retinal detachments at birth: the osteoporosis pseudoglioma syndrome. (11561553)
2001
38
Elevation of vitreous leptin in diabetic retinopathy and retinal detachment. (11006255)
2000
39
Pneumatic retinopexy in a progressive rhegmatogenous retinoschisis retinal detachment. (10815170)
2000
40
Effect of highly active antiretroviral therapy on the incidence of HIV-related cytomegalovirus retinitis and retinal detachment. (10935050)
2000
41
Silicone assisted, argon laser confinement of recurrent proliferative vitreoretinopathy related retinal detachment: a technique to allow silicone oil removal in problem eyes. (9422930)
1997
42
Retinal detachment in Ehlers-Danlos syndrome. Treatment by pars plana vitrectomy]. (9410229)
1997
43
Use of perfluorocarbon liquid in the repair of retinoschisis retinal detachments. (9204829)
1997
44
Retinal detachment and giant retinal tears in aniridia. (7556730)
1995
45
New and previously unidentified retinal breaks in eyes with recurrent retinal detachment with proliferative vitreoretinopathy. (2757545)
1989
46
Regular silicone and fluorosilicone oil in the prevention of retinal detachment caused by experimental proliferative vitreoretinopathy. (3417389)
1988
47
Retinal telangiectasia, retinoschisis and retinal detachment. (6508099)
1984
48
Retinal detachment due to macular holes. (7260014)
1981
49
Wagner's hereditary vitreoretinal degeneration and retinal detachment. (4691317)
1973
50
Sympathetic ophthalmia following an operation for retinal detachment. (13115609)
1953

Genetic Variations for Retinal Detachment

Expression for genes affiliated with Retinal Detachment

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Retinal Detachment

Search GEO for disease gene expression data for Retinal Detachment.

Pathways for genes affiliated with Retinal Detachment

Sources:
38NCBI BioSystems Database, 52QIAGEN, 4Cell Signaling Technology, 54Reactome, 12EMD Millipore, 30KEGG
See all sources

Pathways related to Retinal Detachment according to GeneCards/GeneDecks:

(show all 29)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.5COL2A1
2
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10.5PDGFB
3
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10.4FZD4, PDGFA
4
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10.4PDGFA, PDGFB
510.4FZD4, PDGFB, PDGFA
610.4TIMP2, TIMP1, TGFB2
710.4VEGFA, PDGFB, TIMP2
8
Hide members
10.4TIMP2, TIMP1, MMP3
9
Hide members
10.4TIMP1, PDGFA, VEGFA
10
Cell adhesion ECM remodeling
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10.4COL2A1, TIMP2, TIMP1, MMP3
11
Hide members
10.4COL2A1, TIMP2, TIMP1, MMP3
12
Hide members
10.4COL2A1, PDGFA, PDGFB, VEGFA
1310.4PDGFA, PDGFB, VEGFA, TGFB2
14
Hide members
10.4TIMP2, TIMP1, PDGFA, PDGFB
15
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10.4TIMP2, TIMP1, PDGFA, PDGFB
16
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10.4PDGFB, PDGFA, TIMP1, TIMP2
17
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10.4TGFB2, SRF, PDGFB, PDGFA
18
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10.3SRF, VEGFA, PDGFB, PDGFA
1910.3TGFB2, VEGFA, FZD4, PDGFB, PDGFA
2010.3TGFB2, SRF, FZD4, PDGFB, PDGFA
21
Hide members
10.3TIMP2, TIMP1, PDGFA, PDGFB, TGFB2
22
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10.3TIMP2, TIMP1, PDGFA, PDGFB, TGFB2
23
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10.3TIMP1, PDGFA, PDGFB, TGFB2, TIMP2
24
Hide members
10.3TIMP2, TIMP1, PDGFA, PDGFB, FZD4, TGFB2
25
Hide members
10.3TIMP1, PDGFA, PDGFB, VEGFA, SRF, SERPINF1
26
Hide members
10.3TIMP2, TIMP1, PDGFA, PDGFB, MMP3, SRF
27
Hide members
10.3COL2A1, TIMP2, TIMP1, PDGFA, PDGFB, PRG2
28
Hide members
10.3MMP3, KLK11, COL2A1, TIMP2, TIMP1, PDGFA
29
Hide members
10.2COL2A1, TIMP2, TIMP1, PDGFA, PDGFB, FZD4

Compounds for genes affiliated with Retinal Detachment

Sources:
45Novoseek, 24HMDB, 11DrugBank, 50PharmGKB, 29IUPHAR, 60Tocris Bioscience, 2BitterDB
See all sources

Compounds related to Retinal Detachment according to GeneCards/GeneDecks:

(show top 50)    (show all 114)
idCompoundScoreTop Affiliating Genes
1estrogen4510.9GFAP, GLUL
2matrigel4510.8TGFB2, MMP3
3cycloheximide4510.8COL2A1, GAP43, PDGFB, PDGFA
4procollagen4510.8COL2A1
5alginate4510.8COL2A1
6glutamate4510.8SRF, GFAP, HPRT1, GLUL, FZD4, KLK11
7glycosaminoglycan4510.7TGFB2, SRF, MMP3, TIMP1, TIMP2, COL2A1
8oxygen45 2411.7COL2A1, GFAP, TIMP2, GLUL, PDGFA, PRG2
9nitric oxide45 11 2412.7SRF, SERPINF1, GLUL, GAP43, FZD4, PDGFB
10propionate4510.7TIMP2, GFAP, MMP3, TIMP1
11ribonucleic acid4510.7TGFB2, PDGFB, MMP3, GAP43, PDGFA, TIMP1
12glucose4510.7GFAP, TIMP2, SERPINF1, TGFB2, SRF
13ascorbic acid45 2411.7COL2A1, TIMP2, PDGFA, HPRT1, GLUL, MMP3
14glyceraldehyde 3-phosphate4510.7TIMP2, TIMP1, GFAP, MMP3, HPRT1, GLUL
15paraffin4510.7PDGFB, TGFB2, MMP3, PDGFA, TIMP1, TIMP2
1612-o-tetradecanoylphorbol 13-acetate4510.7SRF, MMP3, TIMP1, PDGFA, GAP43, GLUL
17methotrexate45 50 1112.6CBS, MMP3, SRF, HPRT1, TIMP2, TIMP1
18dexamethasone45 50 29 1113.6PDGFA, SERPINF1, PDGFB, SRF, GFAP, GLUL
19n acetylcysteine4510.6VEGFA, TGFB2, SERPINF1, MMP3, GLUL, TIMP1
20heparin45 29 11 2413.6SRF, SERPINF1, TIMP2, GAP43, TIMP1, PDGFA
21genistein45 29 60 2 11 2415.6SRF, GFAP, TGFB2, VEGFA, PRG2, TIMP1
22progesterone45 60 29 11 2414.6MMP3, PDGFB, GFAP, SRF, TIMP2, TIMP1
23methionine4510.6GAP43, GLUL, CBS, MMP3, GFAP, SERPINF1
24thymidine45 2411.6TIMP2, GLUL, HPRT1, SRF, TGFB2, PDGFB
25nmda45 2911.6GFAP, MMP3, CBS, GAP43, SRF
26oligonucleotide4510.6COL2A1, TGFB2, SRF, CBS, PRG2, TIMP2
27serine4510.6MMP3, GFAP, SRF, HPRT1, GLUL, COL2A1
28cholesterol45 29 11 2413.6MMP3, GLUL, CBS, SRF, TIMP1, GFAP
29arginine4510.6SRF, GFAP, FZD4, PRG2, CBS, GLUL
30vegf4510.6MMP3, GFAP, SRF, SERPINF1, TIMP1, TIMP2
31creatinine4510.6MMP3, GFAP, HPRT1, TGFB2, GLUL, TIMP2
32tyrosine4510.6PDGFB, FZD4, TIMP1, PRG2, VEGFA, GLUL
33zinc45 2411.6TIMP2, COL2A1, GFAP, SRF, PDGFA, PDGFB
34retinoic acid45 2411.6SRF, GAP43, TGFB2, SERPINF1, TIMP2, COL2A1
35tgf beta14510.6TGFB2, MMP3, PDGFB, PDGFA, TIMP1
36lipid4510.6PDGFB, GAP43, TIMP2, COL2A1, SRF, PRG2
37adenylate4510.6TIMP2, TIMP1, GLUL, FZD4, GAP43, HPRT1
38cysteine4510.6PRG2, GAP43, SERPINF1, TGFB2, GFAP, MMP3
39latanoprost45 1111.6TIMP2, TIMP1, MMP3
40hyaluronic acid45 2411.6MMP3, VEGFA, TIMP1, TIMP2, TGFB2
41(4-aminophenyl)mercuric acetate4510.5MMP3, TIMP1
42alanine4510.5GFAP, MMP3, GLUL, GAP43, TIMP1, TIMP2
43pd 98,0594510.5TIMP2, GFAP, MMP3, PDGFB, TIMP1, PDGFA
44h2o24510.5SERPINF1, TIMP2, GAP43, GLUL, HPRT1
45calcium45 50 11 2413.5SRF, TGFB2, SERPINF1, GFAP, COL2A1, KLK11
46cyclosporin a45 29 6012.4TIMP2, TGFB2, PDGFB, SRF
47vitamin a45 11 2412.3TGFB2, SRF, HPRT1, GAP43, TIMP1
48lactate4510.3TIMP2, TIMP1, MMP3, GLUL, GFAP, SRF
49glutamine4510.2TIMP1, GFAP, MMP3, HPRT1, GLUL, TGFB2
50pge24510.1VEGFA

GO Terms for genes affiliated with Retinal Detachment

Sources:
16Gene Ontology
See all sources

Cellular components related to Retinal Detachment according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:00560410.4COL2A1, TIMP2, TIMP1
2platelet alpha granule lumenGO:03109310.4TIMP1, PDGFA, PDGFB, VEGFA, TGFB2
3extracellular regionGO:00557610.2TGFB2, KLK11, COL2A1, TIMP2, TIMP1, PDGFB
4extracellular spaceGO:00561510.1COL2A1, TIMP2, PDGFA, PDGFB, VEGFA, TGFB2
5cell surfaceGO:00998610.0VEGFA, TIMP2, PDGFB, FZD4, PDGFA

Biological processes related to Retinal Detachment according to GeneCards/GeneDecks:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of phosphatidylinositol biosynthetic processGO:01051210.7PDGFB, PDGFA
2positive regulation of protein autophosphorylationGO:03195410.7VEGFA, PDGFB, PDGFA
3response to woundingGO:00961110.7PDGFA, PDGFB, GAP43, GFAP, TGFB2
4activation of protein kinase activityGO:03214710.7PDGFB, VEGFA, TGFB2
5positive regulation of cell divisionGO:05178110.7TGFB2, VEGFA, PDGFB, PDGFA
6platelet degranulationGO:00257610.7TIMP1, PDGFA, PDGFB, VEGFA, TGFB2
7positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathwayGO:03579310.7PDGFB, PDGFA
8extracellular matrix disassemblyGO:02261710.7COL2A1, TIMP2, TIMP1, MMP3
9heart morphogenesisGO:00300710.7TGFB2, VEGFA, COL2A1
10response to hypoxiaGO:00166610.6PDGFA, PDGFB, VEGFA, SRF, TGFB2
11platelet activationGO:03016810.6TIMP1, PDGFA, PDGFB, VEGFA, SRF, TGFB2
12positive regulation of MAP kinase activityGO:04340610.6PDGFA, PDGFB, VEGFA
13positive regulation of phosphatidylinositol 3-kinase cascadeGO:01406810.6TGFB2, PDGFB, PDGFA
14extracellular matrix organizationGO:03019810.6TGFB2, COL2A1, TIMP2, TIMP1, PDGFA, PDGFB
15response to cytokine stimulusGO:03409710.6SRF, TIMP1, TIMP2
16positive regulation of MAPK cascadeGO:04341010.5PDGFB, PDGFA, TIMP2
17positive regulation of cell proliferationGO:00828410.5TIMP1, PDGFA, PDGFB, VEGFA, TGFB2
18cartilage development involved in endochondral bone morphogenesisGO:06035110.5COL2A1, CBS
19blood coagulationGO:00759610.4TIMP1, PDGFA, PDGFB, VEGFA, TGFB2
20cell projection assemblyGO:03003110.4PDGFA, PDGFB
21cell migration involved in sprouting angiogenesisGO:00204210.4SRF, VEGFA
22negative regulation of platelet activationGO:01054410.3PDGFB, PDGFA
23response to drugGO:04249310.1TIMP2, PDGFA, PDGFB, TGFB2

Molecular functions related to Retinal Detachment according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet-derived growth factor bindingGO:04840710.5COL2A1, PDGFB, PDGFA
2metalloendopeptidase inhibitor activityGO:00819110.4TIMP1, TIMP2
3platelet-derived growth factor receptor bindingGO:00516110.4VEGFA, PDGFB, PDGFA
4protein homodimerization activityGO:04280310.4CBS, TGFB2, HPRT1, VEGFA, FZD4, PDGFB
5protein heterodimerization activityGO:04698210.2PDGFA, PDGFB, FZD4, VEGFA, TGFB2
6growth factor activityGO:00808310.1TGFB2, VEGFA, PDGFB, PDGFA

Products for genes affiliated with Retinal Detachment

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Retinal Detachment

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet