Aliases & Classifications for Retinal Detachment

Aliases & Descriptions for Retinal Detachment:

Name: Retinal Detachment 12 29 52 41 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:5327
ICD10 33 H33.2 H33.0
ICD9CM 35 361.9
MeSH 42 D012163
NCIt 47 C26874
UMLS 69 C0035305

Summaries for Retinal Detachment

MedlinePlus : 41 the retina is a layer of tissue in the back of your eye that senses light and sends images to your brain. it provides the sharp, central vision needed for reading, driving, and seeing fine detail. a retinal detachment lifts or pulls the retina from its normal position. it can occur at any age, but it is more common in people over age 40. it affects men more than women and whites more than african americans. a retinal detachment is also more likely to occur in people who are extremely nearsighted have had a retinal detachment in the other eye have a family history of retinal detachment have had cataract surgery have other eye diseases or disorders have had an eye injury symptoms include an increase in the number of floaters, which are little "cobwebs" or specks that float about in your field of vision, and/or light flashes in the eye. it may also seem like there is a "curtain" over your field of vision. a retinal detachment is a medical emergency. if not promptly treated, it can cause permanent vision loss. if you have any symptoms, see an eye care professional immediately. treatment includes different types of surgery. nih: national eye institute

MalaCards based summary : Retinal Detachment is related to diverticulosis of bowel, hernia, and retinal detachment and stickler sydrome, type i, nonsyndromic ocular. An important gene associated with Retinal Detachment is COL2A1 (Collagen Type II Alpha 1 Chain), and among its related pathways/superpathways are ERK Signaling and Phospholipase-C Pathway. The drugs Prednisolone and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and brain, and related phenotypes are cardiovascular system and behavior/neurological

Wikipedia : 71 Retinal detachment is a disorder of the eye in which the retina separates from the layer underneath.... more...

Related Diseases for Retinal Detachment

Diseases related to Retinal Detachment via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 258)
id Related Disease Score Top Affiliating Genes
1 diverticulosis of bowel, hernia, and retinal detachment 11.9
2 stickler sydrome, type i, nonsyndromic ocular 11.9
3 knobloch syndrome, type 1 11.7
4 knobloch syndrome 11.6
5 persistent hyperplastic primary vitreous, autosomal recessive 11.5
6 retinoschisis 11.4
7 persistent hyperplastic primary vitreous 11.2
8 myopia 11.2
9 coats disease 11.2
10 exudative vitreoretinopathy 11.2
11 pars planitis 11.1
12 retinal disease 11.1
13 kniest dysplasia 11.1
14 retinochoroidal coloboma 11.1
15 wagner syndrome 11.1
16 retinitis 11.1
17 ectopia lentis et pupillae 10.9
18 papillorenal syndrome 10.9
19 exudative vitreoretinopathy 4 10.9
20 vitreoretinopathy, neovascular inflammatory 10.9
21 exudative vitreoretinopathy 1 10.9
22 stickler syndrome, type i 10.9
23 exudative vitreoretinopathy 2, x-linked 10.9
24 stickler syndrome, type v 10.8
25 stickler syndrome, type ii 10.8
26 donnai-barrow syndrome 10.8
27 myopia, high, with cataract and vitreoretinal degeneration 10.8
28 stickler syndrome, type iv 10.8
29 exudative vitreoretinopathy 5 10.8
30 microcephaly with or without chorioretinopathy, lymphedema, or mental retardation 10.8
31 coloboma of optic nerve 10.8
32 exudative vitreoretinopathy 3 10.8
33 exudative vitreoretinopathy 6 10.8
34 cavitary optic disc anomalies 10.8
35 microcephaly and chorioretinopathy, autosomal recessive, 3 10.8
36 spondyloocular syndrome 10.8
37 snowflake vitreoretinal degeneration 10.8
38 wagner syndrome 1 10.8
39 sed congenita 10.8
40 alezzandrini syndrome 10.8
41 isolated ectopia lentis 10.8
42 macular holes 10.5
43 choroiditis 10.4
44 marshall syndrome 10.3 COL11A1 COL2A1
45 cataract 10.2
46 fibrochondrogenesis 1 10.2 COL11A1 COL2A1
47 cytomegalovirus retinitis 10.2
48 athabaskan brainstem dysgenesis syndrome 10.2 CAPN5 RS1 VEGFA
49 bipolar i disorder 10.1 FGF2 IL6 VEGFA
50 vitreous detachment 10.1

Comorbidity relations with Retinal Detachment via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Retinal Detachment:



Diseases related to Retinal Detachment

Symptoms & Phenotypes for Retinal Detachment

Human phenotypes related to Retinal Detachment:

32
id Description HPO Frequency HPO Source Accession
1 retinal detachment 32 HP:0000541

MGI Mouse Phenotypes related to Retinal Detachment:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.23 VEGFA COL18A1 COL2A1 FGF2 FZD4 GFAP
2 behavior/neurological MP:0005386 10.18 VEGFA COL2A1 FGF2 FZD4 GFAP GLUL
3 growth/size/body region MP:0005378 10.14 FZD4 GFAP GLUL IL6 KCNJ13 LRP5
4 mortality/aging MP:0010768 10.1 CAPN5 COL11A1 COL2A1 FGF2 FZD4 GFAP
5 nervous system MP:0003631 10.1 FZD4 GFAP GLUL IL6 LRP5 NDP
6 digestive/alimentary MP:0005381 10.03 COL11A1 COL2A1 FZD4 GFAP IL6 KCNJ13
7 hearing/vestibular/ear MP:0005377 9.85 COL11A1 COL2A1 FGF2 FZD4 NDP TSPAN12
8 pigmentation MP:0001186 9.7 COL18A1 FZD4 LRP5 NDP PDGFB RS1
9 skeleton MP:0005390 9.65 COL11A1 COL18A1 COL2A1 FGF2 IL6 KCNJ13
10 vision/eye MP:0005391 9.44 COL18A1 COL2A1 FGF2 FZD4 GFAP IL6

Drugs & Therapeutics for Retinal Detachment

Drugs for Retinal Detachment (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 222)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
2
Lidocaine Approved, Vet_approved Phase 4,Phase 3 137-58-6 3676
3
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
4
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 124-94-7 31307
5
Ranibizumab Approved Phase 4,Phase 3,Phase 2,Phase 1 347396-82-1 459903
6
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
7
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 216974-75-3
8
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2 50-02-2 5743
9
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
10
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
11
Isotretinoin Approved Phase 4 4759-48-2 5538 5282379
12
Verteporfin Approved, Investigational Phase 4,Phase 2,Phase 1 129497-78-5
13
Ofloxacin Approved Phase 4 82419-36-1 4583
14
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
15
Norfloxacin Approved Phase 4 70458-96-7 4539
16
Gatifloxacin Approved, Investigational Phase 4 112811-59-3 5379
17
Gemifloxacin Approved, Investigational Phase 4 175463-14-6 5464436 9571107
18
Temazepam Approved Phase 4,Phase 3,Phase 2 846-50-4 5391
19
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
20
Rasagiline Approved Phase 4 136236-51-6 3052776
21 triamcinolone acetonide Phase 4,Phase 3,Phase 2
22 Prednisolone acetate Phase 4
23 Analgesics Phase 4,Phase 2
24 glucocorticoids Phase 4,Phase 3,Phase 2,Early Phase 1
25 Mitogens Phase 4,Phase 2,Phase 3,Phase 1
26 Gastrointestinal Agents Phase 4,Phase 2,Phase 1
27 Sodium Channel Blockers Phase 4
28 Neuroprotective Agents Phase 4,Phase 2
29 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
30 Cyclooxygenase Inhibitors Phase 4
31 Tetrahydrozoline Phase 4,Phase 2,Phase 3,Phase 1
32 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 2
33 Analgesics, Non-Narcotic Phase 4,Phase 2
34 Dermatologic Agents Phase 4,Phase 2,Phase 1
35 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
36 Ophthalmic Solutions Phase 4,Phase 2,Phase 3,Phase 1
37 Anesthetics Phase 4,Phase 2,Phase 3
38 Triamcinolone diacetate Phase 4,Phase 3,Phase 2
39 Triamcinolone hexacetonide Phase 4,Phase 3,Phase 2
40 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
41 Diuretics, Potassium Sparing Phase 4,Phase 2,Phase 3,Phase 1
42 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 1
43 Anesthetics, Local Phase 4
44 Angiogenesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
45 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
46 Angiogenesis Modulating Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Endothelial Growth Factors Phase 4,Phase 2,Phase 3,Phase 1
48 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
49 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 3
50 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 247)
id Name Status NCT ID Phase
1 Adjunctive Local Application of Lidocaine During Scleral Buckling Under General Anesthesia Unknown status NCT01417572 Phase 4
2 Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity Unknown status NCT00634972 Phase 4
3 IntraVitreal Triamcinolone Acetonide: Preventing Raised Eye-pressure by Tracking Elevations After Topical Steroids Unknown status NCT00744666 Phase 4
4 On-label tReatment With Intravitreal Aflibercept injectiOn for Patients With Persistent Pigment epitheliaL Detachments in Neovascular Age Related Macular Degeneration (AMD) Unknown status NCT01670162 Phase 4
5 Ranibizumab in Diabetic Vitrectomy Unknown status NCT01306981 Phase 4
6 An Observational Study of Oral Fluoroquinolones and the Risk of Retinal Detachment Completed NCT01881438 Phase 4
7 Isotretinoin for Proliferative Vitreoretinopathy Completed NCT01445028 Phase 4
8 Postoperative Pain Control Following Vitreoretinal Surgery Completed NCT01995045 Phase 4
9 Prospective Randomized Controlled Study of Intravitreal Injection of Bevacizumab for Proliferative Diabetic Retinopathy Completed NCT01854593 Phase 4
10 Preoperative Ketorolac for Pain Control in Scleral Buckle Surgery Completed NCT02729285 Phase 4
11 Open Label to Study to Evaluate Effect of Alfilbercept on Patients With (FVPED) Fibrovascular Pigment Epithelial Detachment Completed NCT01495208 Phase 4
12 Intravitreal Ranibizumab in Retinal Pigment Epithelial Detachments Completed NCT00976222 Phase 4
13 Intravitreal Aflibercept Injection for the Treatment of Submacular Vascularized Pigment Epithelial Detachment Completed NCT01722656 Phase 4
14 Eylea to Treat Retinal Pigment Epithelial Detachment (RPED) Secondary to Wet Age-Related Macular Degeneration (wAMD) Completed NCT02142296 Phase 4
15 Study to Investigate the Safety and Efficacy of Ranibizumab in Patients With Choroidal Neovascularisation Due to Causes Other Than Age Related Macular Degeneration Completed NCT01628354 Phase 4
16 Aurolab Hydrophobic Foldable Intraocular Lens Study Completed NCT00449267 Phase 4
17 Assessment of Early Changes in SD-OCT After Initiation of a Treatment by Intravitreal Aflibercept (EYLEA®)START Completed NCT02246829 Phase 4
18 Combined Therapy in Age-Related Macular Degeneration (ARMD) Completed NCT00805649 Phase 4
19 Rasagiline (Azilect) - Neuroprotection for Macula-off Retinal Detachment Recruiting NCT02068625 Phase 4
20 Influence of Diabetes Control on Treatment of Diabetic Macular Edema With Ranibizumab Recruiting NCT02665689 Phase 4
21 CPAP Effect on the Progression of Diabetic Retinopathy in Patients With Sleep Apnea Recruiting NCT02874313 Phase 4
22 Efficacy of Fixed Monthly Dosing of Ranibizumab in Neovascular Age-related Macular Degeneration Recruiting NCT02944227 Phase 4
23 Safety and Efficacy of Switching From Aflibercept to Ranibizumab in Patients With nAMD Recruiting NCT02161575 Phase 4
24 The Efficacy Assessment of Intravitreal Injection of Conbercept in Patients With Polypoidal Choroidal Vasculopathy (PCV) Recruiting NCT03159884 Phase 4
25 TTT Versus TTT and Triamcinolone to Decrease Exudation in Choroidal Melanoma After Proton Beam Therapy Active, not recruiting NCT02379000 Phase 4
26 Treatment of AMD With Rheohemapheresis /RHF/ Active, not recruiting NCT01943396 Phase 4
27 PRedictive Factors and Changes From Treatment in Idiopathic Polypoidal Choroidal Vasuclopathy Versus Central Serous Chorioretinopathy Versus Neovascular Age Related Macular Degeneration With afLibercept Not yet recruiting NCT02681783 Phase 4
28 A Study Comparing Efficacy and Safety of "Treat-and-Extend" Regimen Versus PRN of Conbercept in AMD Not yet recruiting NCT02802657 Phase 4
29 Study Trial of Dexamethasone Use for Alleviation of Symptoms After Scleral Buckle Eye Surgery Withdrawn NCT01326585 Phase 4
30 Triple Treatment for Detachment of Retinal Pigment Epithelium Secondary to Polypoidal Choroidal Vasculopathy Withdrawn NCT01666236 Phase 4
31 CANadian Study in Patients With Wet AMD, Evaluating the Efficacy and Safety of Switching From Intravitreal Aflibercept to RanIbizumab Withdrawn NCT02634970 Phase 4
32 Pressurized PPV 23GA Vitrectomy in Complicated Diabetic Tractional Retinal Detachment Unknown status NCT00404209 Phase 3
33 Comparison High-Density Silicone Oils in Retinal Detachment Unknown status NCT00403702 Phase 2, Phase 3
34 Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment Unknown status NCT00370201 Phase 3
35 Surgical Management of Pseudophakic and Aphakic Retinal Detachment; a Randomized Clinical Trial Unknown status NCT00370279 Phase 3
36 Evaluation of Ranibizumab in Proliferative Diabetic Retinopathy (PDR) Requiring Vitrectomy Unknown status NCT00516464 Phase 3
37 Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis Unknown status NCT01768078 Phase 3
38 Perfluorocarbon Perfused Vitrectomy and 3D Vitrectomy System in Advanced Diabetic Retinopathy Unknown status NCT00407108 Phase 3
39 Intravitreal Bevacizumab for Management of Active Progressive Proliferative Diabetic Retinopathy (PDR) Unknown status NCT00370721 Phase 3
40 Intravitreal Bevacizumab for the Treatment of Central Serous Chorioretinopathy Unknown status NCT00418431 Phase 2, Phase 3
41 A Safety and Efficacy Study of Vitreosolve® for Non-Proliferative Diabetic Retinopathy Subjects Unknown status NCT00908778 Phase 3
42 Comparison of Air and Expansile Gas in Pneumatic Retinopexy Completed NCT00120445 Phase 3
43 Clinical Trial of Cryotherapy Versus Postoperative Laser Photocoagulation Completed NCT01068379 Phase 3
44 The Silicone Study Completed NCT00000140 Phase 3
45 Diabetic Retinopathy Vitrectomy Study (DRVS) Completed NCT00000154 Phase 3
46 Safety and Efficacy of Propranolol in Newborns With Retinopathy of Prematurity Completed NCT01079715 Phase 2, Phase 3
47 Comparison of AC and PC Lenses After Vitreous Loss During ECCE Completed NCT00453011 Phase 3
48 Bevacizumab and Long Acting Gas in Diabetic Vitrectomy Completed NCT00656435 Phase 3
49 Bevacizumab Versus Ranibizumab for Diabetic Retinopathy Completed NCT00545870 Phase 3
50 Green Laser Photocoagulation Study in Proliferative Diabetic Retinopathy Completed NCT00355680 Phase 3

Search NIH Clinical Center for Retinal Detachment

Cochrane evidence based reviews: retinal detachment

Genetic Tests for Retinal Detachment

Genetic tests related to Retinal Detachment:

id Genetic test Affiliating Genes
1 Retinal Detachment 29

Anatomical Context for Retinal Detachment

MalaCards organs/tissues related to Retinal Detachment:

39
Eye, Retina, Brain, Endothelial, Liver, T Cells, Cortex

Publications for Retinal Detachment

Articles related to Retinal Detachment:

(show top 50) (show all 1070)
id Title Authors Year
1
Primary Retinal Detachment Surgery: Changes in Treatment and Outcome in an Austrian Tertiary Eye Center. ( 28068654 )
2017
2
Correlation between miR-148 Expression in Vitreous and Severity of Rhegmatogenous Retinal Detachment. ( 28261609 )
2017
3
RETINAL DETACHMENT ASSOCIATED WITH PERIPAPILLARY STAPHYLOMA IMAGED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY. ( 28072615 )
2017
4
SURGICAL MANAGEMENT OF RETINAL DETACHMENT IN OSTEOGENESIS IMPERFECTA: CASE REPORT AND REVIEW OF THE LITERATURE. ( 28085759 )
2017
5
Comparison of outcomes: scleral buckling and pars plana vitrectomy versus vitrectomy alone for primary repair of rhegmatogenous retinal detachment. ( 28053500 )
2017
6
OUTER RETINAL TUBULATIONS IN CHRONIC RHEGMATOGENOUS RETINAL DETACHMENT. ( 28085760 )
2017
7
UNUSUAL SEROUS RETINAL DETACHMENT IN A PATIENT WITH WALDENSTROM MACROGLOBULINEMIA: A CASE REPORT. ( 28106626 )
2017
8
SURGICAL OUTCOMES AND COMPLICATIONS OF RHEGMATOGENOUS RETINAL DETACHMENT IN EYES WITH CHORIORETINAL COLOBOMA: The Results of the KKESH International Collaborative Retina Study Group. ( 28067725 )
2017
9
Results of Peripheral Vitrectomy Under Air in Rhegmatogenous Retinal Detachment. ( 28060394 )
2017
10
Exome sequencing identifies a de novo mutation of CTNNB1 gene in a patient mainly presented with retinal detachment, lens and vitreous opacities, microcephaly, and developmental delay: Case report and literature review. ( 28514307 )
2017
11
Retinal Detachment in a Combined Case of Stickler Syndrome and X-Linked Retinoschisis. ( 28060400 )
2017
12
Monitoring retinoschisis and non-acute retinal detachment by optical coherence tomography: morphologic aspects and clinical impact. ( 28321986 )
2017
13
Preoperative aqueous humour flare values do not predict proliferative vitreoretinopathy in patients with rhegmatogenous retinal detachment. ( 28077370 )
2017
14
Repair of Total Tractional Retinal Detachment in Norrie Disease: Report of Technique and Successful Surgical Outcome. ( 28297040 )
2017
15
Retinal changes in fellow eye detected by ultra-widefield imaging and slit-lamp biomicroscopy in patients with primary rhegmatogenous retinal detachment. ( 27595666 )
2016
16
Retinal Detachment and Proliferative Vitreoretinopathy. ( 26501375 )
2016
17
Retinal Detachment in Down Syndrome: Characteristics and Surgical Outcomes. ( 27123341 )
2016
18
Management of postvitrectomy retinal detachment due to multiple laser-induced retinal holes. ( 27664228 )
2016
19
Timing and Outcomes of Vitreoretinal Surgery after Traumatic Retinal Detachment. ( 27999681 )
2016
20
Missed retinal breaks in rhegmatogenous retinal detachment. ( 27990367 )
2016
21
Bilateral choroidal detachment with exudative retinal detachment in a patient with septicaemia. ( 27999127 )
2016
22
Inverted Internal Limiting Membrane Insertion for Macular Hole-Associated Retinal Detachment in High Myopia. ( 27174666 )
2016
23
SUBFOVEAL CHOROIDAL THICKNESS CHANGE AFTER PARS PLANA VITRECTOMY IN RECENT ONSET RHEGMATOGENOUS RETINAL DETACHMENT. ( 27579730 )
2016
24
Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia. ( 26730175 )
2016
25
Pars Plana Vitrectomy Alone for the Management of Pseudophakic Rhegmatogenous Retinal Detachment with Only Inferior Breaks. ( 27126928 )
2016
26
Short stature, platyspondyly, hip dysplasia, and retinal detachment: an atypical type II collagenopathy caused by a novel mutation in the C-propeptide region of COL2A1: a case report. ( 27955642 )
2016
27
Integrating Scleral Buckling, Transscleral Drainage of Subretinal Fluid, Intravitreal Anti-Vascular Endothelial Growth Factor, and Laser Photocoagulation in Stage 3B Coats' Total Retinal Detachment. ( 27631484 )
2016
28
Cataract Surgery after Retinal Detachment Surgery with Arruga's Sutures: Case Report. ( 28050328 )
2016
29
INCIDENCE AND RELATION WITH ANATOMICAL AND FUNCTIONAL VARIABLES OF POSTOPERATIVE MACULAR DISPLACEMENT IN RHEGMATOGENOUS RETINAL DETACHMENT. ( 27115857 )
2016
30
Scleral resection in chronic central serous chorioretinopathy complicated by exudative retinal detachment. ( 27617266 )
2016
31
Topical difluprednate for treatment of serous retinal detachment and panuveitis associated with Vogt-Koyanagi-Harada disease. ( 27582676 )
2016
32
Surgical challenges and outcomes of rhegmatogenous retinal detachment in albinism. ( 26611845 )
2016
33
Point-of-Care Ultrasound Diagnosis of Bilateral Retinal Detachment Associated With Vogt-Koyanagi-Harada Disease in the Pediatric Emergency Department. ( 26890299 )
2016
34
EXUDATIVE RETINAL DETACHMENT CAUSED BY A CHOROIDAL NEOVASCULAR MEMBRANE IN HALLERMANN-STREIFF SYNDROME. ( 27648586 )
2016
35
Pneumatic Retinopexy for Rhegmatogenous Retinal Detachment in Pseudophakia. ( 27599596 )
2016
36
Vitrectomy with and without encircling band for pseudophakic retinal detachment: VIPER Study Report No 2-main results. ( 27609785 )
2016
37
Etiologies and surgical outcomes of pediatric retinal detachment in Hong Kong. ( 27628429 )
2016
38
Anatomical and Gene Expression Changes in the Retinal Pigmented Epithelium Atrophy 1 (rpea1) Mouse: A Potential Model of Serous Retinal Detachment. ( 27603725 )
2016
39
Comments on temporary resolution of foveal schisis following vitrectomy with silicon oil tamponade in X-linked retinoschisis with retinal detachment. ( 27146945 )
2016
40
CONCENTRATIONS OF VITREAL CYTOKINES IN RHEGMATOGENOUS RETINAL DETACHMENT. ( 27125084 )
2016
41
Decreased hyaluronan concentration during primary rhegmatogenous retinal detachment. ( 27198637 )
2016
42
Pioneering surgery for retinal detachment in Australasia: a review. ( 27187199 )
2016
43
Scleral Buckling for Rhegmatogenous Retinal Detachment Associated with Pars Planitis. ( 27688907 )
2016
44
WIDE-FIELD INFRARED IMAGING: A Descriptive Review of Characteristics of Retinoschisis, Retinal Detachment, and Schisis Detachments. ( 26807632 )
2016
45
Risk of Tractional Retinal Detachment Following Intravitreal Bevacizumab Along with Subretinal Fluid Drainage and Cryotherapy for Stage 3B Coats' Disease. ( 27162454 )
2016
46
RAPID MACULAR HOLE FORMATION, SPONTANEOUS CLOSURE, AND REOPENING AFTER PARS PLANA VITRECTOMY FOR MACULA-SPARING RETINAL DETACHMENT. ( 27145172 )
2016
47
An Unusual Case of Extensive Lattice Degeneration and Retinal Detachment. ( 27630875 )
2016
48
ACUTE SEROUS RETINAL DETACHMENT IN IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION. ( 27203562 )
2016
49
Profiles of Inflammatory Cytokines in the Vitreous Fluid from Patients with Rhegmatogenous Retinal Detachment and Their Correlations with Clinical Features. ( 28074184 )
2016
50
Long-term surgical outcomes of retinal detachment in patients with Stickler syndrome. ( 27574392 )
2016

Variations for Retinal Detachment

Expression for Retinal Detachment

Search GEO for disease gene expression data for Retinal Detachment.

Pathways for Retinal Detachment

Pathways related to Retinal Detachment according to GeneCards Suite gene sharing:

(show all 17)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.58 CAPN5 COL11A1 COL18A1 COL2A1 FGF2 FZD4
2
Show member pathways
12.9 COL11A1 COL18A1 COL2A1 FGF2 IL6 PDGFB
3
Show member pathways
12.83 FGF2 FZD4 IL6 LRP5 PDGFB VEGFA
4
Show member pathways
12.72 CAPN5 COL11A1 COL2A1 PDGFB VEGFA
5 12.47 FGF2 FZD4 IL6 PDGFB VEGFA
6
Show member pathways
12.45 CAPN5 COL11A1 COL18A1 COL2A1 FGF2 PDGFB
7 12.36 COL2A1 FGF2 IL6 PDGFB VEGFA
8 11.98 FZD4 IL6 LRP5 VEGFA
9 11.83 FGF2 IL6 PDGFB VEGFA
10 11.8 FGF2 IL6 VEGFA
11 11.73 COL2A1 FGF2 GFAP
12 11.54 COL2A1 FGF2 IL6 PDGFB
13 11.51 COL2A1 FGF2 VEGFA
14 11.49 FGF2 IL6 PDGFB
15 11.16 FGF2 GFAP PDGFB VEGFA
16 10.71 FGF2 PDGFB VEGFA
17 10.61 FGF2 IL6 PDGFB VEGFA

GO Terms for Retinal Detachment

Cellular components related to Retinal Detachment according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.83 CAPN5 FZD4 NDP PDGFB VEGFA
2 proteinaceous extracellular matrix GO:0005578 9.72 ADAMTSL4 COL11A1 COL18A1 COL2A1 VEGFA
3 endoplasmic reticulum lumen GO:0005788 9.63 ADAMTSL4 COL11A1 COL18A1 COL2A1 IL6 PDGFB
4 collagen trimer GO:0005581 9.58 COL11A1 COL18A1 COL2A1
5 basement membrane GO:0005604 9.54 COL18A1 COL2A1 SERPINF1
6 extracellular matrix GO:0031012 9.5 ADAMTSL4 COL11A1 COL18A1 COL2A1 NDP PDGFB
7 extracellular space GO:0005615 9.36 ADAMTSL4 COL11A1 COL18A1 COL2A1 FGF2 IL6
8 extracellular region GO:0005576 10 ADAMTSL4 COL11A1 COL18A1 COL2A1 FGF2 IL6

Biological processes related to Retinal Detachment according to GeneCards Suite gene sharing:

(show all 26)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.99 FGF2 FZD4 IL6 LRP5 NDP PDGFB
2 angiogenesis GO:0001525 9.91 COL18A1 FGF2 TSPAN12 VEGFA
3 positive regulation of cell proliferation GO:0008284 9.88 COL18A1 FGF2 IL6 LRP5 PDGFB VEGFA
4 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.8 IL6 PDGFB VEGFA
5 canonical Wnt signaling pathway GO:0060070 9.79 FZD4 LRP5 NDP
6 sensory perception of sound GO:0007605 9.78 COL11A1 COL2A1 FZD4 NDP
7 positive regulation of endothelial cell proliferation GO:0001938 9.77 FGF2 PDGFB VEGFA
8 somatic stem cell population maintenance GO:0035019 9.77 FGF2 LDB2 LRP5
9 collagen catabolic process GO:0030574 9.76 COL11A1 COL18A1 COL2A1
10 positive regulation of epithelial cell proliferation GO:0050679 9.74 GLUL IL6 VEGFA
11 positive regulation of MAP kinase activity GO:0043406 9.72 FGF2 PDGFB VEGFA
12 heart morphogenesis GO:0003007 9.71 COL11A1 COL2A1 VEGFA
13 positive regulation of cell division GO:0051781 9.7 FGF2 PDGFB VEGFA
14 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.67 FZD4 IL6 LRP5 NDP
15 visual perception GO:0007601 9.65 COL11A1 COL18A1 COL2A1 NDP RS1
16 cell migration involved in sprouting angiogenesis GO:0002042 9.63 FGF2 VEGFA
17 positive chemotaxis GO:0050918 9.63 FGF2 PDGFB VEGFA
18 bone remodeling GO:0046849 9.62 IL6 LRP5
19 regulation of angiogenesis GO:0045765 9.61 FGF2 IL6 TSPAN12
20 proteoglycan metabolic process GO:0006029 9.58 COL11A1 COL2A1
21 positive regulation of blood vessel endothelial cell migration GO:0043536 9.5 FGF2 PDGFB VEGFA
22 retinal blood vessel morphogenesis GO:0061304 9.49 FZD4 LRP5
23 extracellular matrix organization GO:0030198 9.43 ADAMTSL4 COL11A1 COL18A1 COL2A1 FGF2 PDGFB
24 retina vasculature morphogenesis in camera-type eye GO:0061299 9.33 FZD4 LRP5 NDP
25 extracellular matrix-cell signaling GO:0035426 8.8 FZD4 LRP5 NDP
26 multicellular organism development GO:0007275 10.1 FGF2 FZD4 LRP5 PDGFB RS1 SERPINF1

Molecular functions related to Retinal Detachment according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.56 FGF2 IL6 NDP VEGFA
2 platelet-derived growth factor receptor binding GO:0005161 9.37 PDGFB VEGFA
3 chemoattractant activity GO:0042056 9.33 FGF2 PDGFB VEGFA
4 platelet-derived growth factor binding GO:0048407 9.32 COL2A1 PDGFB
5 Wnt-activated receptor activity GO:0042813 9.13 FZD4 LRP5 TSPAN12
6 growth factor activity GO:0008083 9.02 FGF2 IL6 NDP PDGFB VEGFA

Sources for Retinal Detachment

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
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44 MGI
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48 NDF-RT
51 NINDS
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54 OMIM
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59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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