Aliases & Classifications for Retinal Detachment

MalaCards integrated aliases for Retinal Detachment:

Name: Retinal Detachment 53 12 28 51 40 41 14 69

Characteristics:

OMIM:

53
Inheritance:
autosomal dominant


HPO:

31
retinal detachment:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 53 180050
Disease Ontology 12 DOID:5327
ICD10 32 H33.2 H33.0
ICD9CM 34 361.9
MeSH 41 D012163
NCIt 46 C26874
MedGen 39 C0035305
SNOMED-CT via HPO 65 263681008
UMLS 69 C0035305

Summaries for Retinal Detachment

MedlinePlus : 40 The retina is a layer of tissue in the back of your eye that senses light and sends images to your brain. It provides the sharp, central vision needed for reading, driving, and seeing fine detail. A retinal detachment lifts or pulls the retina from its normal position. It can occur at any age, but it is more common in people over age 40. It affects men more than women and whites more than African Americans. A retinal detachment is also more likely to occur in people who Are extremely nearsighted Have had a retinal detachment in the other eye Have a family history of retinal detachment Have had cataract surgery Have other eye diseases or disorders Have had an eye injury Symptoms include an increase in the number of floaters, which are little "cobwebs" or specks that float about in your field of vision, and/or light flashes in the eye. It may also seem like there is a "curtain" over your field of vision. A retinal detachment is a medical emergency. If not promptly treated, it can cause permanent vision loss. If you have any symptoms, see an eye care professional immediately. Treatment includes different types of surgery. NIH: National Eye Institute

MalaCards based summary : Retinal Detachment is related to persistent hyperplastic primary vitreous, autosomal recessive and persistent hyperplastic primary vitreous. An important gene associated with Retinal Detachment is COL2A1 (Collagen Type II Alpha 1 Chain), and among its related pathways/superpathways are ERK Signaling and Pathways in cancer. The drugs Lidocaine and Ketorolac have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and brain, and related phenotypes are cardiovascular system and behavior/neurological

OMIM : 53 Primary or spontaneous detachment of the retina occurs due to underlying ocular disease and often involves the vitreous as well as the retina. The precipitating event is formation of a retinal tear or hole, which permits fluid to accumulate under the sensory layers of the retina and creates an intraretinal cleavage that destroys the neurosensory process of visual reception. Vitreoretinal degeneration and tear formation are painless phenomena, and in most cases, significant vitreoretinal pathology is found only after detachment of the retina starts to cause loss of vision or visual field. Without surgical intervention, retinal detachment will almost inevitably lead to total blindness (summary by McNiel and McPherson, 1971). (180050)

Wikipedia : 72 Retinal detachment is a disorder of the eye in which the retina separates from the layer underneath.... more...

Related Diseases for Retinal Detachment

Diseases related to Retinal Detachment via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 288)
# Related Disease Score Top Affiliating Genes
1 persistent hyperplastic primary vitreous, autosomal recessive 33.2 ATOH7 TSPAN12
2 persistent hyperplastic primary vitreous 32.3 ATOH7 FZD4 NDP
3 coats disease 31.6 FZD4 NDP RS1 TSPAN12 VEGFA
4 myopia 31.6 COL11A1 COL18A1 COL2A1 VEGFA
5 exudative vitreoretinopathy 1 31.4 CTNNB1 FZD4 LRP5 NDP TSPAN12 VEGFA
6 exudative vitreoretinopathy 31.3 ATOH7 CTNNB1 FZD4 LRP5 NDP TSPAN12
7 retinal perforation 30.5 COL11A1 COL2A1 KCNJ13
8 retinal telangiectasia 30.1 FZD4 NDP TSPAN12
9 vitreoretinal degeneration 29.8 COL11A1 COL18A1 COL2A1 KCNJ13
10 osteoporosis-pseudoglioma syndrome 29.8 CTNNB1 FZD4 LRP5 NDP
11 macular retinal edema 29.8 CAPN5 SERPINF1 VEGFA
12 norrie disease 29.7 FZD4 LRP5 NDP TSPAN12
13 stickler syndrome, type i, nonsyndromic ocular 12.1
14 lattice degeneration of retina leading to retinal detachment 12.0
15 diverticulosis of bowel, hernia, and retinal detachment 12.0
16 knobloch syndrome 1 12.0
17 knobloch syndrome 11.9
18 retinoschisis 1, x-linked, juvenile 11.5
19 vitreoretinopathy, neovascular inflammatory 11.5
20 morning glory syndrome 11.2
21 pars planitis 11.2
22 retinal disease 11.2
23 kniest dysplasia 11.2
24 spondyloepiphyseal dysplasia congenita 11.2
25 spondyloepimetaphyseal dysplasia, strudwick type 11.2
26 retinochoroidal coloboma 11.2
27 wagner syndrome 11.2
28 retinitis 11.2
29 stickler syndrome, type i 11.0
30 papillorenal syndrome 11.0
31 ectopia lentis et pupillae 11.0
32 exudative vitreoretinopathy 2, x-linked 11.0
33 exudative vitreoretinopathy 4 11.0
34 coloboma of optic nerve 10.9
35 wagner vitreoretinopathy 10.9
36 microcephaly with or without chorioretinopathy, lymphedema, or mental retardation 10.9
37 vitreoretinal degeneration, snowflake type 10.9
38 donnai-barrow syndrome 10.9
39 stickler syndrome, type ii 10.9
40 exudative vitreoretinopathy 3 10.9
41 spondyloocular syndrome 10.9
42 cavitary optic disc anomalies 10.9
43 exudative vitreoretinopathy 5 10.9
44 stickler syndrome, type iv 10.9
45 stickler syndrome, type v 10.9
46 myopia, high, with cataract and vitreoretinal degeneration 10.9
47 microcephaly and chorioretinopathy, autosomal recessive, 3 10.9
48 exudative vitreoretinopathy 6 10.9
49 exudative vitreoretinopathy 7 10.9
50 joint laxity, short stature, and myopia 10.9

Comorbidity relations with Retinal Detachment via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Retinal Detachment:



Diseases related to Retinal Detachment

Symptoms & Phenotypes for Retinal Detachment

Symptoms via clinical synopsis from OMIM:

53
Eyes:
retinal detachment
no myopia


Clinical features from OMIM:

180050

Human phenotypes related to Retinal Detachment:

31
# Description HPO Frequency HPO Source Accession
1 retinal detachment 31 HP:0000541

MGI Mouse Phenotypes related to Retinal Detachment:

43 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.26 CTNNB1 FZD4 COL18A1 COL2A1 GFAP ATOH7
2 behavior/neurological MP:0005386 10.24 ATOH7 CTNNB1 COL18A1 FZD4 COL2A1 KCNJ13
3 nervous system MP:0003631 10.17 CTNNB1 COL11A1 FZD4 COL18A1 COL2A1 GFAP
4 growth/size/body region MP:0005378 10.14 CAPN5 CTNNB1 COL11A1 FZD4 COL2A1 GLUL
5 digestive/alimentary MP:0005381 10.03 CTNNB1 COL11A1 FZD4 COL2A1 GFAP KCNJ13
6 craniofacial MP:0005382 10 CTNNB1 COL11A1 COL18A1 COL2A1 KCNJ13 LRP5
7 normal MP:0002873 9.91 ATOH7 CTNNB1 FZD4 COL2A1 GFAP LDB2
8 hearing/vestibular/ear MP:0005377 9.85 CTNNB1 COL11A1 FZD4 COL2A1 TSPAN12 NDP
9 pigmentation MP:0001186 9.81 FZD4 COL18A1 ADAMTSL4 CTNNB1 RS1 SERPINF1
10 skeleton MP:0005390 9.61 CTNNB1 COL11A1 COL18A1 COL2A1 KCNJ13 SERPINF1
11 vision/eye MP:0005391 9.47 FZD4 COL18A1 COL2A1 GFAP ADAMTSL4 ATOH7

Drugs & Therapeutics for Retinal Detachment

Drugs for Retinal Detachment (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 188)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Phase 3 137-58-6 3676
2
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
3
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
4
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
5
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 124-94-7 31307
6
Ranibizumab Approved Phase 4,Phase 3,Phase 2,Phase 1 347396-82-1 459903
7
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 216974-75-3
8
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
9
Gatifloxacin Approved, Investigational Phase 4 112811-59-3 5379
10
Gemifloxacin Approved, Investigational Phase 4 175463-14-6 9571107 5464436
11
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
12
Moxifloxacin Approved, Investigational Phase 4 151096-09-2, 354812-41-2 152946
13
Norfloxacin Approved Phase 4 70458-96-7 4539
14
Ofloxacin Approved Phase 4 82419-36-1 4583
15
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 5311068 56032 68602
16
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
17
Isotretinoin Approved Phase 4 4759-48-2 5282379 5538
18
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
19
Verteporfin Approved, Investigational Phase 4,Phase 2 129497-78-5
20
Rasagiline Approved Phase 4 136236-51-6 3052776
21
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2 50-02-2 5743
22 Anesthetics Phase 4,Phase 2,Phase 3
23 Anesthetics, Local Phase 4
24 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 3
25 Central Nervous System Depressants Phase 4,Phase 3,Phase 2
26 Diuretics, Potassium Sparing Phase 4
27 Peripheral Nervous System Agents Phase 4,Phase 2
28 Sodium Channel Blockers Phase 4
29 Analgesics Phase 4
30 Analgesics, Non-Narcotic Phase 4
31 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Early Phase 1
32 Anti-Inflammatory Agents, Non-Steroidal Phase 4
33 Antirheumatic Agents Phase 4,Phase 3
34 Cyclooxygenase Inhibitors Phase 4
35 Ketorolac Tromethamine Phase 4
36 Antiemetics Phase 4,Phase 2
37 Antineoplastic Agents, Hormonal Phase 4,Phase 2
38 Autonomic Agents Phase 4,Phase 2
39 Gastrointestinal Agents Phase 4,Phase 2,Phase 1
40 glucocorticoids Phase 4,Phase 3,Phase 2,Early Phase 1
41 Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
42 Hormones Phase 4,Phase 3,Phase 2,Early Phase 1
43 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
44 Immunosuppressive Agents Phase 4,Phase 3,Phase 2
45 Methylprednisolone acetate Phase 4
46 Methylprednisolone Hemisuccinate Phase 4
47 Neuroprotective Agents Phase 4,Phase 2
48 Ophthalmic Solutions Phase 4,Phase 2,Phase 1
49 Prednisolone acetate Phase 4
50 Prednisolone hemisuccinate Phase 4

Interventional clinical trials:

(show top 50) (show all 184)

# Name Status NCT ID Phase Drugs
1 Adjunctive Local Application of Lidocaine During Scleral Buckling Under General Anesthesia Unknown status NCT01417572 Phase 4 lidocaine
2 Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity Unknown status NCT00634972 Phase 4 ACULAR;REFRESH TEARS;placebo
3 IntraVitreal Triamcinolone Acetonide: Preventing Raised Eye-pressure by Tracking Elevations After Topical Steroids Unknown status NCT00744666 Phase 4 Prednisolone 1% topical eye drops
4 On-label tReatment With Intravitreal Aflibercept injectiOn for Patients With Persistent Pigment epitheliaL Detachments in Neovascular Age Related Macular Degeneration (AMD) Unknown status NCT01670162 Phase 4 Aflibercept
5 Ranibizumab in Diabetic Vitrectomy Unknown status NCT01306981 Phase 4 Ranibizumab;Saline
6 An Observational Study of Oral Fluoroquinolones and the Risk of Retinal Detachment Completed NCT01881438 Phase 4
7 Dexmedetomidine Versus Propofol in Vitreoretinal Surgery Completed NCT01001429 Phase 4 Dexmedetomidine infusion;propofol
8 Isotretinoin for Proliferative Vitreoretinopathy Completed NCT01445028 Phase 4 Isotretinoin
9 Postoperative Pain Control Following Vitreoretinal Surgery Completed NCT01995045 Phase 4 Triamcinolone;Bupivicaine Hydrochloride
10 Prospective Randomized Controlled Study of Intravitreal Injection of Bevacizumab for Proliferative Diabetic Retinopathy Completed NCT01854593 Phase 4 Bevacizumab
11 Preoperative Ketorolac for Pain Control in Scleral Buckle Surgery Completed NCT02729285 Phase 4 Ketorolac Tromethamine;placebo
12 Open Label to Study to Evaluate Effect of Alfilbercept on Patients With (FVPED) Fibrovascular Pigment Epithelial Detachment Completed NCT01495208 Phase 4 Aflibercept
13 Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule Opacification Completed NCT03321253 Phase 4
14 Intravitreal Aflibercept Injection for the Treatment of Submacular Vascularized Pigment Epithelial Detachment Completed NCT01722656 Phase 4 Aflibercept
15 Intravitreal Ranibizumab in Retinal Pigment Epithelial Detachments Completed NCT00976222 Phase 4 intravitreal injection with ranibizumab
16 Eylea to Treat Retinal Pigment Epithelial Detachment (RPED) Secondary to Wet Age-Related Macular Degeneration (wAMD) Completed NCT02142296 Phase 4 Eylea
17 Study to Investigate the Safety and Efficacy of Ranibizumab in Patients With Choroidal Neovascularisation Due to Causes Other Than Age Related Macular Degeneration Completed NCT01628354 Phase 4 Ranibizumab
18 Aurolab Hydrophobic Foldable Intraocular Lens Study Completed NCT00449267 Phase 4
19 Rasagiline (Azilect) - Neuroprotection for Macula-off Retinal Detachment Recruiting NCT02068625 Phase 4 Rasagiline;Placebo
20 Evaluation of the Effect of Intravitreal Injections of Anti-VEGF on Macular Perfusion in Diabetic Patients Using OCTA Recruiting NCT03246152 Phase 4 Bevacizumab
21 Influence of Diabetes Control on Treatment of Diabetic Macular Edema With Ranibizumab Recruiting NCT02665689 Phase 4 ranibizumab
22 TTT Versus TTT and Triamcinolone to Decrease Exudation in Choroidal Melanoma After Proton Beam Therapy Active, not recruiting NCT02379000 Phase 4 Triamcinolone Acetonide
23 Study Trial of Dexamethasone Use for Alleviation of Symptoms After Scleral Buckle Eye Surgery Withdrawn NCT01326585 Phase 4 Dexamethasone Sodium Phosphate Injection;Saline Injection
24 Triple Treatment for Detachment of Retinal Pigment Epithelium Secondary to Polypoidal Choroidal Vasculopathy Withdrawn NCT01666236 Phase 4
25 Pressurized PPV 23GA Vitrectomy in Complicated Diabetic Tractional Retinal Detachment Unknown status NCT00404209 Phase 3
26 Comparison High-Density Silicone Oils in Retinal Detachment Unknown status NCT00403702 Phase 2, Phase 3 Oxane HD [oil-RMN3-mixture];Densiron [(F6H8)
27 Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment Unknown status NCT00370201 Phase 3 colchicine
28 Surgical Management of Pseudophakic and Aphakic Retinal Detachment; a Randomized Clinical Trial Unknown status NCT00370279 Phase 3
29 Evaluation of Ranibizumab in Proliferative Diabetic Retinopathy (PDR) Requiring Vitrectomy Unknown status NCT00516464 Phase 3 Lucentis (ranibizumab)
30 Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis Unknown status NCT01768078 Phase 3
31 Perfluorocarbon Perfused Vitrectomy and 3D Vitrectomy System in Advanced Diabetic Retinopathy Unknown status NCT00407108 Phase 3
32 Intravitreal Bevacizumab for Management of Active Progressive Proliferative Diabetic Retinopathy (PDR) Unknown status NCT00370721 Phase 3 bevacizumab
33 Comparison of Air and Expansile Gas in Pneumatic Retinopexy Completed NCT00120445 Phase 3
34 Clinical Trial of Cryotherapy Versus Postoperative Laser Photocoagulation Completed NCT01068379 Phase 3
35 The Silicone Study Completed NCT00000140 Phase 3 Perfluoropropane;Sulfur Hexafluoride;Silicone Oil
36 Diabetic Retinopathy Vitrectomy Study (DRVS) Completed NCT00000154 Phase 3
37 Safety and Efficacy of Propranolol in Newborns With Retinopathy of Prematurity Completed NCT01079715 Phase 2, Phase 3 Propranolol
38 Comparison of AC and PC Lenses After Vitreous Loss During ECCE Completed NCT00453011 Phase 3
39 Bevacizumab and Long Acting Gas in Diabetic Vitrectomy Completed NCT00656435 Phase 3 Bevacizumab
40 Bevacizumab Versus Ranibizumab for Diabetic Retinopathy Completed NCT00545870 Phase 3 bevacizumab;Ranibizumab
41 Green Laser Photocoagulation Study in Proliferative Diabetic Retinopathy Completed NCT00355680 Phase 3
42 Triamcinolone Acetonide in Silicone-Filled Eyes as Adjunctive Treatment for Proliferative Vitreoretinopathy Completed NCT00373282 Phase 3 Triamcinolone acetonide
43 A Single Centre Study to Compare the Efficacy and Safety of Femtosecond Laser-Assisted Versus Manual Cataract Surgery Completed NCT01373853 Phase 3
44 Lucentis for Age-related Macular Degeneration Pigment Epithelial Detachments Completed NCT00590694 Phase 2, Phase 3 ranibizumab
45 Prophylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients With Retinal Detachment. Recruiting NCT02834559 Phase 3 5-fluorouracil and low molecular weight heparin;Placebo
46 25-Gauge Vitrectomy With Ranibizumab or Triamcinolone Acetonide on Proliferative Diabetic Retinopathy in China Recruiting NCT02328118 Phase 2, Phase 3 Ranibizumab;Triamcinolone Acetonide
47 25-G Vitrectomy With Ranibizumab or Triamcinolone Acetonide on PDR in China-Randomized Clinical Trial Recruiting NCT02447185 Phase 3 Ranibizumab;Triamcinolone Acetonide
48 Pre-Operative Intravitreal Bevacizumab for Tractional Retinal Detachment Secondary to Proliferative Diabetic Retinopathy Active, not recruiting NCT01976923 Phase 3 Intravitreal bevacizumab
49 Prospective, Randomized, Multicentre, Open-label, Phase II / III Study to Assess Efficacy and Safety of Ranibizumab 0.5 mg Intravitreal Injections Plus Panretinal Photocoagulation (PRP) Versus PRP in Monotherapy in the Treatment of Subjects With High Risk Active, not recruiting NCT01941329 Phase 2, Phase 3 Intravitreous injection of ranibizumab
50 A Study of the Safety, Tolerability, and Efficacy of IVT Pre-op 0.3mg Pegaptanib Sodium Versus Sham, for Management of Tractional Retinal Detachment and Vitreous Hemorrhage With Proliferative Diabetic Retinopathy Withdrawn NCT01589718 Phase 3 Macugen;Sham

Search NIH Clinical Center for Retinal Detachment

Cochrane evidence based reviews: retinal detachment

Genetic Tests for Retinal Detachment

Genetic tests related to Retinal Detachment:

# Genetic test Affiliating Genes
1 Retinal Detachment 28

Anatomical Context for Retinal Detachment

MalaCards organs/tissues related to Retinal Detachment:

38
Eye, Retina, Brain, Endothelial, Liver, Testes, T Cells

Publications for Retinal Detachment

Articles related to Retinal Detachment:

(show top 50) (show all 1128)
# Title Authors Year
1
Nonaccidental injury presenting as unilateral Retinal Detachment in two infants. ( 29410140 )
2018
2
Jules Gonin and the Nobel Prize: pioneer of retinal detachment surgery who almost received a Nobel Prize in medicine. ( 29372074 )
2018
3
Acute retinal detachment induced by the Valsalva manoeuvre in morning glory disc anomaly. ( 29374647 )
2018
4
Long-Term Outcomes of Total Exudative Retinal Detachments in Stage 3B Coats Disease. ( 29361355 )
2018
5
Segmental Analysis of Macular Layers in Patients With Rhegmatogenous Retinal Detachment Treated With Perfluoropropane or Silicon Oil. ( 29304265 )
2018
6
Solitary Retinal Capillary Hemangioma with Nonlipid Exudative Retinal Detachment. ( 29389404 )
2018
7
Coats disease with exudative retinal detachment simulating cysticercus cyst: misleading ultrasonography! ( 29321199 )
2018
8
Final anatomic and visual outcomes appear independent of duration of silicone oil intraocular tamponade in complex retinal detachment surgery. ( 29375996 )
2018
9
Intraocular currents, Bernoulli's principle and non-drainage scleral buckling for rhegmatogenous retinal detachment. ( 29350687 )
2018
10
Risk Factors for Development of Rhegmatogenous Retinal Detachment in Patients with Uveitis. ( 29420113 )
2018
11
Development of Surgical Management in Primary Rhegmatogenous Retinal Detachment Treatment from 2009 to 2015. ( 29364728 )
2018
12
Bilateral total retinal detachment at birth: a case report of Walker-Warburg syndrome. ( 29386918 )
2018
13
IMPACT OF INNER LIMITING MEMBRANE PEELING ON VISUAL RECOVERY AFTER VITRECTOMY FOR PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT INVOLVING THE FOVEA. ( 29394235 )
2018
14
The use of ocular ultrasound to diagnose retinal detachment: a case demonstrating the sonographic findings. ( 29404803 )
2018
15
RECURRENT OPENING AND CLOSURE OF MACULAR HOLE AFTER PARS PLANA VITRECTOMY FOR RHEGMATOGENOUS RETINAL DETACHMENT. ( 29315126 )
2018
16
Foveal Avascular Zone Area Changes Analyzed Using OCT Angiography after Successful Rhegmatogenous Retinal Detachment Repair. ( 29451996 )
2018
17
Proteome and Metabolome of Subretinal Fluid in Central Serous Chorioretinopathy and Rhegmatogenous Retinal Detachment: A Pilot Case Study. ( 29359109 )
2018
18
Pseudophakic retinal detachment in young-aged patients. ( 28859157 )
2017
19
Failed Pneumatic Retinopexy for Rhegmatogenous Retinal Detachment Repair in Ocular Albinism: Clues to the Role of Melanin in Retinal Pigment Epithelium Pump Function. ( 29253306 )
2017
20
Posteriorly dislocated capsular tension ring leading to rhegmatogenous retinal detachment. ( 28939620 )
2017
21
Cost-Utility of Evaluation for Posterior Vitreous Detachment and Prophylaxis of Retinal Detachment. ( 28732590 )
2017
22
Late presentation of retinal detachment in India: A comparison between developing nations. ( 28816226 )
2017
23
Comparison of outcomes: scleral buckling and pars plana vitrectomy versus vitrectomy alone for primary repair of rhegmatogenous retinal detachment. ( 28053500 )
2017
24
Correlation between miR-148 Expression in Vitreous and Severity of Rhegmatogenous Retinal Detachment. ( 28261609 )
2017
25
Exome sequencing identifies a de novo mutation of CTNNB1 gene in a patient mainly presented with retinal detachment, lens and vitreous opacities, microcephaly, and developmental delay: Case report and literature review. ( 28514307 )
2017
26
Results of Peripheral Vitrectomy Under Air in Rhegmatogenous Retinal Detachment. ( 28060394 )
2017
27
Serous retinal detachment after panretinal photocoagulation for proliferative diabetic retinopathy: a case report. ( 28923115 )
2017
28
Accuracy of deep learning, a machine-learning technology, using ultra-wide-field fundus ophthalmoscopy for detecting rhegmatogenous retinal detachment. ( 28842613 )
2017
29
Retinal detachment and microangiopathy in mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes syndrome. ( 29217043 )
2017
30
Primary Retinal Detachment Surgery: Changes in Treatment and Outcome in an Austrian Tertiary Eye Center. ( 28068654 )
2017
31
Can emergency physicians accurately distinguish retinal detachment from posterior vitreous detachment with point-of-care ocular ultrasound? ( 29042095 )
2017
32
OUTER RETINAL TUBULATIONS IN CHRONIC RHEGMATOGENOUS RETINAL DETACHMENT. ( 28085760 )
2017
33
Surgical Management of a Patient with Anterior Megalophthalmos, Lens Subluxation, and a High Risk of Retinal Detachment. ( 28203198 )
2017
34
Craniofacial linear scleroderma associated with retinal telangiectasia and exudative retinal detachment. ( 28528991 )
2017
35
Extramedullary Relapse of Acute Myelogenous Leukemia Presenting as a Large Serous Retinal Detachment. ( 28868277 )
2017
36
BAX and BCL2 Gene Polymorphisms in Rhegmatogenous Retinal Detachment. ( 28877516 )
2017
37
Pneumatic retinopexy combined with scleral buckling in the management of relatively complicated cases of rhegmatogenous retinal detachment: A multicenter, retrospective, observational consecutive case series(). ( 28840752 )
2017
38
Revesz syndrome masquerading as traumatic retinal detachment. ( 28866069 )
2017
39
RHEGMATOGENOUS RETINAL DETACHMENT: A RARE OCULAR MANIFESTATION OF PROTEUS SYNDROME. ( 27285287 )
2017
40
Outcomes of 23-gauge pars plana vitrectomy combined with phacoemulsification and capsulotomy without intraocular lens implantation in rhegmatogenous retinal detachment associated with choroidal detachment. ( 28834901 )
2017
41
Double Internal Limiting Membrane Insertion for Macular Hole-Associated Retinal Detachment. ( 28845304 )
2017
42
Bilateral Exudative Retinal Detachment in Septo-Optic Dysplasia. ( 29317570 )
2017
43
The Genetic Causes of Nonsyndromic Congenital Retinal Detachment: A Genetic and Phenotypic Study of Pakistani Families. ( 28192794 )
2017
44
EFFICACY OF THE INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE WITH VITRECTOMY FOR RETINAL DETACHMENT ASSOCIATED WITH MYOPIC MACULAR HOLES. ( 28225722 )
2017
45
A Modified Technique for the Transconjunctival and Sutureless External Drainage of Subretinal Fluid in Bullous Exudative Retinal Detachment Using a 24-G i.v. Catheter. ( 28866667 )
2017
46
SURGICAL MANAGEMENT OF RETINAL DETACHMENT IN OSTEOGENESIS IMPERFECTA: CASE REPORT AND REVIEW OF THE LITERATURE. ( 28085759 )
2017
47
Repair of Total Tractional Retinal Detachment in Norrie Disease: Report of Technique and Successful Surgical Outcome. ( 28297040 )
2017
48
Intraoperative optical coherence tomography assisted analysis of pars Plana vitrectomy for retinal detachment in morning glory syndrome: a case report. ( 28764684 )
2017
49
Perioperative factors that are significantly correlated with final visual acuity in eyes after successful rhegmatogenous retinal detachment surgery. ( 28902881 )
2017
50
RETINAL DETACHMENT ASSOCIATED WITH PERIPAPILLARY STAPHYLOMA IMAGED WITH SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY. ( 28072615 )
2017

Variations for Retinal Detachment

Expression for Retinal Detachment

Search GEO for disease gene expression data for Retinal Detachment.

Pathways for Retinal Detachment

GO Terms for Retinal Detachment

Cellular components related to Retinal Detachment according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.88 CAPN5 FZD4 NDP PDGFB VEGFA
2 extracellular space GO:0005615 9.81 ADAMTSL4 COL11A1 COL18A1 COL2A1 NDP PDGFB
3 proteinaceous extracellular matrix GO:0005578 9.65 ADAMTSL4 COL11A1 COL18A1 COL2A1 VEGFA
4 collagen trimer GO:0005581 9.63 COL11A1 COL18A1 COL2A1
5 basement membrane GO:0005604 9.61 COL18A1 COL2A1 SERPINF1
6 Wnt signalosome GO:1990909 9.37 CTNNB1 LRP5
7 endoplasmic reticulum lumen GO:0005788 9.35 ADAMTSL4 COL11A1 COL18A1 COL2A1 PDGFB
8 glial cell projection GO:0097386 9.32 GFAP GLUL
9 extracellular matrix GO:0031012 9.1 COL11A1 COL18A1 COL2A1 NDP PDGFB SERPINF1
10 extracellular region GO:0005576 10.06 ADAMTSL4 COL11A1 COL18A1 COL2A1 NDP PDGFB

Biological processes related to Retinal Detachment according to GeneCards Suite gene sharing:

(show all 22)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.99 CTNNB1 FZD4 LRP5 NDP PDGFB
2 positive regulation of cell proliferation GO:0008284 9.97 COL18A1 CTNNB1 LRP5 PDGFB VEGFA
3 negative regulation of gene expression GO:0010629 9.86 CTNNB1 PDGFB SERPINF1 VEGFA
4 Wnt signaling pathway GO:0016055 9.85 CTNNB1 FZD4 LRP5 NDP
5 kidney development GO:0001822 9.75 CTNNB1 SERPINF1 VEGFA
6 sensory perception of sound GO:0007605 9.73 COL11A1 COL2A1 FZD4 NDP
7 positive regulation of DNA binding transcription factor activity GO:0051091 9.71 CTNNB1 FZD4 LRP5 NDP
8 collagen catabolic process GO:0030574 9.7 COL11A1 COL18A1 COL2A1
9 vasculogenesis GO:0001570 9.67 CTNNB1 FZD4 VEGFA
10 heart morphogenesis GO:0003007 9.65 COL11A1 COL2A1 VEGFA
11 visual perception GO:0007601 9.65 COL11A1 COL18A1 COL2A1 NDP RS1
12 canonical Wnt signaling pathway GO:0060070 9.62 CTNNB1 FZD4 LRP5 NDP
13 positive regulation of neuroblast proliferation GO:0002052 9.61 CTNNB1 VEGFA
14 cartilage condensation GO:0001502 9.6 COL11A1 COL2A1
15 gastrulation with mouth forming second GO:0001702 9.58 CTNNB1 LRP5
16 proteoglycan metabolic process GO:0006029 9.54 COL11A1 COL2A1
17 positive regulation of mesenchymal cell proliferation GO:0002053 9.54 CTNNB1 LRP5 VEGFA
18 retinal blood vessel morphogenesis GO:0061304 9.46 FZD4 LRP5
19 extracellular matrix organization GO:0030198 9.43 ADAMTSL4 COL11A1 COL18A1 COL2A1 GFAP PDGFB
20 retina vasculature morphogenesis in camera-type eye GO:0061299 9.33 FZD4 LRP5 NDP
21 extracellular matrix-cell signaling GO:0035426 8.8 FZD4 LRP5 NDP
22 multicellular organism development GO:0007275 10.05 ATOH7 FZD4 LRP5 PDGFB RS1 SERPINF1

Molecular functions related to Retinal Detachment according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet-derived growth factor receptor binding GO:0005161 9.16 PDGFB VEGFA
2 platelet-derived growth factor binding GO:0048407 8.96 COL2A1 PDGFB
3 Wnt-activated receptor activity GO:0042813 8.8 FZD4 LRP5 TSPAN12

Sources for Retinal Detachment

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
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35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
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43 MGI
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51 Novoseek
53 OMIM
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58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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